PRINCETON, N.J., March 05, 2020 (GLOBE NEWSWIRE) -- PDS Biotechnology Corporation(Nasdaq: PDSB), a clinical-stage immuno-oncology company developing multiple therapies based on the Companys proprietary Versamune T-cell activating technology, today announced that it has been granted U.S. Patent No. 15/702,063 titled Stimulation of an Immune Response by Enantiomers of Cationic Lipids by the United States Patent and Trademark Office (USPTO).
The expansion of our international patent portfolio furthers protects our novel Versamune platform and the development of our robust pipeline, commented Dr. Frank Bedu-Addo, CEO of PDS Biotech. "As we advance our lead program, PDS0101 towards three Phase 2 studies this year with leaders in the field of immuno-oncology, we believe that our Versamune platform holds the potential to significantly improve clinical outcomes for patients.
The U.S. Patent No. 15/702,063 titled Stimulation of an Immune Response by Enantiomers of Cationic Lipids provides protection for compositions of matter for the Versamune platform including its chemical design and methods of delivery including oral, injectable and topical. The patent covers immune activating compositions containing the immunologically active enantiomer of the cationic lipid 1,2-dioleoyl-3-trimethyl-ammonium-propane (R-DOTAP) and a specific antigen. This patent has also been issued in several other countries including the European Union, Japan, Canada and Australia. The PDS Versamune patent portfolio also includes broader cationic lipid compositions that activate the immune system. The combination of Versamune with various antigens forms the basis for PDS Biotechs broad immuno-oncology pipeline, including its lead candidate PDS0101 for the treatment of advanced human papillomavirus (HPV) related cancers.
About PDS Biotechnology
PDS Biotech is a clinical-stage immuno-oncology company developing multiple therapies based on the Companys proprietary Versamune T-cell activating technology platform. The Versamune platform effectively delivers tumor-specific antigens for in vivo uptake and processing, while also activating a critical immunological pathway, the type 1 interferon pathway, thus resulting in the production of potent tumor-specific killer T-cells. Using Versamune, PDS Biotech is engineering therapies designed to better recognize cancer cells and break down their defense systems to effectively attack and destroy tumors. PDS Biotechs pipeline combines the Versamune technology with tumor-specific antigens across several cancer types. To learn more, please visit http://www.pdsbiotech.com or follow us on Twitter at @PDSBiotech.
About PDS0101
PDS Biotechs lead candidate, PDS0101, combines the utility of the Versamune platform with targeted antigens in HPV-expressing cancers. In partnership with Merck, PDS Biotech is advancing a combination of PDS0101 and KEYTRUDA to a Phase 2 study in first line treatment of recurrent or metastatic head and neck cancer. In partnership with the National Cancer Institute (NCI), PDS Biotech is also advancing a combination of PDS0101 and two clinical stage immunotherapies to a Phase 2 study in advanced HPV-associated cancers. A third phase 2 study is to be performed in advanced localized cervical cancer combining PDS0101 with the chemoradiotherapy, which is the standard of care.
Forward Looking Statements
This communication contains forward-looking statements (including within the meaning of Section 21E of the United States Securities Exchange Act of 1934, as amended, and Section 27A of the United States Securities Act of 1933, as amended) concerning PDS Biotechnology Corporation (the Company) and other matters. These statements may discuss goals, intentions and expectations as to future plans, trends, events, results of operations or financial condition, or otherwise, based on current beliefs of the Companys management, as well as assumptions made by, and information currently available to, management. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as may, will, should, would, expect, anticipate, plan, likely,believe,estimate,project,intend,and other similar expressions among others. Statements that are not historical facts are forward-looking statements. Forward-looking statements are based on current beliefs and assumptions that are subject to risks and uncertainties and are not guarantees of future performance. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors, including, without limitation: the Companys ability to protect its intellectual property rights;the Companys anticipated capital requirements, including the Companys anticipated cash runway and the Companys current expectations regarding its plans for future equity financings; the timing for the Company or its partners to initiate the planned clinical trials for its lead asset, PDS0101; the Companys interpretation of the results of its Phase 1 trial for PDS0101 and whether such results are sufficient to support additional trials or the future success of such trials;the successful implementation of the Companys research and development programs and collaborations, including any collaboration studies concerning PDS0101 and the Companys interpretation of the results and findings of such programs and collaborations and whether such results are sufficient to support the future success of the Companys product candidates; the acceptance by the market of the Companys product candidates, if approved;the timing of and the Companys ability to obtain and maintainU.S. Food and Drug Administrationor other regulatory authority approval of, or other action with respect to, the Companys product candidates;and other factors, including legislative, regulatory, political and economic developmentsnot within the Companys control. The foregoing review of important factors that could cause actual events to differ from expectations should not be construed as exhaustive and should be read in conjunction with statements that are included herein and elsewhere, including the risk factors included in the Companys annual and periodic reports filed with the SEC. The forward-looking statements are made only as of the date of this press release and, except as required by applicable law, the Company undertakes no obligation to revise or update any forward-looking statement, or to make any other forward-looking statements, whether as a result of new information, future events or otherwise.
Media & Investor Relations Contact:
Deanne RandolphPDS BiotechPhone: +1 (908) 517-3613Email: drandolph@pdsbiotech.com
Tram Bui / Alexander LoboThe Ruth GroupPhone: +1 (646) 536-7035 / +1 (646) 536-7037Email: tbui@theruthgroup.com / alobo@theruthgroup.com
Read the original:
PDS Biotechnology Expands Patent Portfolio for its Novel Versamune PlatformGranted Composition of Matter Patent for Versamune Platform by the United...
- Angel Biotechnology (ABH) - Video [Last Updated On: November 28th, 2011] [Originally Added On: November 28th, 2011]
- Curing the entire world through biotechnology [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Biotechnological innovation on Farming Skill [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Growth and development of Biotechnology [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Biotechnology: Boon to Human being [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Philippines banks on biotechnology to deal with enviromentally friendly issues, food security considerations [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Philippines banks on biotechnology to deal with enviromentally friendly issues, food security considerations [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Biotechnology: Boon to Human being [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Growth and development of Biotechnology [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Biotechnological innovation on Farming Skill [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Curing the entire world through biotechnology [Last Updated On: December 18th, 2011] [Originally Added On: December 18th, 2011]
- Scientists make ethical stem cells from skin of a rat [Last Updated On: January 22nd, 2012] [Originally Added On: January 22nd, 2012]
- India emerging as a global hub for stem cell research [Last Updated On: January 22nd, 2012] [Originally Added On: January 22nd, 2012]
- India emerging as a global hub for stem cell research [Last Updated On: January 22nd, 2012] [Originally Added On: January 22nd, 2012]
- Scientists make ethical stem cells from skin of a rat [Last Updated On: January 22nd, 2012] [Originally Added On: January 22nd, 2012]
- Alzheimer Disease - New Drugs, Markets and Companies [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Amazing Stem Cell Therapy Results | Before [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Stemcell therapy for pets - Mi Mascota - Video [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Stem cells for dogs? New pain management therapy works for pets - Video [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Riot's Lameness Moving Exam Pre Stem Cell Therapy - Video [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Riot's Lameness Palpation Exam Pre Stem Cell Therapy - Video [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- Ariel's Stem Cell Miracle! - Video [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- South Korea again gives a go ahead to use of human eggs in cloning research [Last Updated On: February 5th, 2012] [Originally Added On: February 5th, 2012]
- South Korea again gives a go ahead to use of human eggs in cloning research [Last Updated On: February 5th, 2012] [Originally Added On: February 5th, 2012]
- Angel Biotechnology - Contracts with Materia Medica [Last Updated On: February 7th, 2012] [Originally Added On: February 7th, 2012]
- Cellerant Therapeutics Appoints Lowell E. Sears to Board of Directors [Last Updated On: February 21st, 2012] [Originally Added On: February 21st, 2012]
- Angel Biotechnology - Grant of Share Options [Last Updated On: February 27th, 2012] [Originally Added On: February 27th, 2012]
- RBCC Closes Deal with Game Changing Biotech Firm [Last Updated On: March 16th, 2012] [Originally Added On: March 16th, 2012]
- The year of the dragon looks auspicious for Australian Biotechnology [Last Updated On: March 25th, 2012] [Originally Added On: March 25th, 2012]
- The year of the dragon looks auspicious for Australian Biotechnology [Last Updated On: March 25th, 2012] [Originally Added On: March 25th, 2012]
- David Allan Lauded for Leadership – Biotechnology Leader Named to Industry Award [Last Updated On: May 9th, 2012] [Originally Added On: May 9th, 2012]
- Angel Biotechnology - Angel signs new contract with ReNeuron [Last Updated On: May 17th, 2012] [Originally Added On: May 17th, 2012]
- MYOS Names Veteran Biotechnology Executive Dr. Sol J. Barer to Chair Scientific Advisory Board [Last Updated On: June 27th, 2012] [Originally Added On: June 27th, 2012]
- StemCells and Keryx Biopharmaceuticals Showing Strong Gains as Biotechnology Industry Soars in 2012 [Last Updated On: July 24th, 2012] [Originally Added On: July 24th, 2012]
- Osiris Therapeutics and Pluristem Therapeutics Showing Impressive Growth as Biotech Industry Thrives in 2012 [Last Updated On: August 4th, 2012] [Originally Added On: August 4th, 2012]
- Allele Biotechnology Announces New Advance in Production of Human Stem Cells [Last Updated On: September 14th, 2012] [Originally Added On: September 14th, 2012]
- BIO Announces Therapeutic Workshops for 11th Annual BIO Investor Forum [Last Updated On: September 25th, 2012] [Originally Added On: September 25th, 2012]
- Biotech Industry Applauds Introduction of the High Technology Small Business Research Incentives Act [Last Updated On: October 2nd, 2012] [Originally Added On: October 2nd, 2012]
- Biotech Industry Look to Benefit From New Act Designed to Promote R&D Joint Ventures [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- David Lichtenstein: Biotechnology is Rich Area for Investment [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- Donna Dickenson introduces Bioethics - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- Coare Biotechnology and ChemDiv Establish Co-Marketing and Service Collaboration [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- blood banks | Umbilical Cord Blood Banking Could Be an Investment in Our Future Health - Video [Last Updated On: November 12th, 2012] [Originally Added On: November 12th, 2012]
- Research and Markets: Research Report on the Biotechnology Market in India 2012 [Last Updated On: November 18th, 2012] [Originally Added On: November 18th, 2012]
- Life Un(Ltd), Charis Thompson, Three Times a Woman- A Gendered Economy of Stem Cell Innovation Pt. 2 - Video [Last Updated On: November 30th, 2012] [Originally Added On: November 30th, 2012]
- Life UnLtd, Charis Thompson, Three Times a Woman A Gendered Economy of Stem Cell Innovation Pt 1 - Video [Last Updated On: November 30th, 2012] [Originally Added On: November 30th, 2012]
- Biotechnology: Things you should know about Gene Therapy [Last Updated On: December 2nd, 2012] [Originally Added On: December 2nd, 2012]
- Biotechnology: Things you should know about Gene Therapy [Last Updated On: December 2nd, 2012] [Originally Added On: December 2nd, 2012]
- Top trends for Biotechnology [Last Updated On: December 9th, 2012] [Originally Added On: December 9th, 2012]
- Top trends for Biotechnology [Last Updated On: December 9th, 2012] [Originally Added On: December 9th, 2012]
- Angel Biotechnology losses widen [Last Updated On: December 10th, 2012] [Originally Added On: December 10th, 2012]
- Why Biotech ETFs are a Top Sector in 2012 [Last Updated On: December 19th, 2012] [Originally Added On: December 19th, 2012]
- Things to know about the real fountain of youth [Last Updated On: January 11th, 2013] [Originally Added On: January 11th, 2013]
- Things to know about the real fountain of youth [Last Updated On: January 20th, 2013] [Originally Added On: January 20th, 2013]
- DNA testing is Good or Bad: Let’s Discuss [Last Updated On: March 2nd, 2013] [Originally Added On: March 2nd, 2013]
- Computer Review Announces New Tools to Deal with the Flood of Information from the Biotechnology Sector [Last Updated On: March 7th, 2013] [Originally Added On: March 7th, 2013]
- DNA testing is Good or Bad: Let’s Discuss [Last Updated On: March 10th, 2013] [Originally Added On: March 10th, 2013]
- The Mystery about Cyanide Taste [Last Updated On: March 31st, 2013] [Originally Added On: March 31st, 2013]
- The Mystery about Cyanide Taste [Last Updated On: April 14th, 2013] [Originally Added On: April 14th, 2013]
- Are Biodegradable Heart Stents Safe? [Last Updated On: April 17th, 2013] [Originally Added On: April 17th, 2013]
- Piper Jaffray Biotechnology Analyst Participates in Historical Medical Event at the Vatican [Last Updated On: April 17th, 2013] [Originally Added On: April 17th, 2013]
- Are Biodegradable Heart Stents Safe? [Last Updated On: April 21st, 2013] [Originally Added On: April 21st, 2013]
- TaiGen Biotechnology Announces Submission of New Drug Application for Nemonoxacin in Taiwan and Mainland China [Last Updated On: May 17th, 2013] [Originally Added On: May 17th, 2013]
- How good to use home pregnancy tests [Last Updated On: June 1st, 2013] [Originally Added On: June 1st, 2013]
- How good to use home pregnancy tests [Last Updated On: June 2nd, 2013] [Originally Added On: June 2nd, 2013]
- Questions you should ask to doctor for Alzheimer disease [Last Updated On: July 6th, 2013] [Originally Added On: July 6th, 2013]
- Questions you should ask to doctor for Alzheimer disease [Last Updated On: July 7th, 2013] [Originally Added On: July 7th, 2013]
- BetaStem Therapeutics Retains Conditas Biotechnology Group for Business Development and Corporate Strategy [Last Updated On: July 18th, 2013] [Originally Added On: July 18th, 2013]
- Sanguine BioSciences Announces Distribution Partnership with AMS Biotechnology [Last Updated On: August 8th, 2013] [Originally Added On: August 8th, 2013]
- Matric Revision: Life Sciences: Genetics: Biotechnology (5/9): Cloning (1/4) - Video [Last Updated On: October 27th, 2013] [Originally Added On: October 27th, 2013]
- Matric Revision: Life Sciences: Genetics: Biotechnology (6/9): Cloning (2/4) - Video [Last Updated On: October 29th, 2013] [Originally Added On: October 29th, 2013]
- History of biotechnology - Wikipedia, the free encyclopedia [Last Updated On: December 16th, 2013] [Originally Added On: December 16th, 2013]
- Exciting business ideas in biotechnology and healthcare - Video [Last Updated On: February 19th, 2014] [Originally Added On: February 19th, 2014]
- Crippled canines get new leash on life [Last Updated On: March 27th, 2014] [Originally Added On: March 27th, 2014]
- Stem Cell Treatment for Dogs - pet insurance [Last Updated On: March 27th, 2014] [Originally Added On: March 27th, 2014]
- New patenting guidelines needed for biotechnology, experts argue [Last Updated On: April 24th, 2014] [Originally Added On: April 24th, 2014]
- New tumor-targeting agent images and treats wide variety of cancers [Last Updated On: June 24th, 2014] [Originally Added On: June 24th, 2014]
- San Diego Hosts World's Largest Biotechnology Convention - Video [Last Updated On: June 28th, 2014] [Originally Added On: June 28th, 2014]
- Shot in the arm for research on disease biology [Last Updated On: July 13th, 2014] [Originally Added On: July 13th, 2014]
- biotechnology -- Encyclopedia Britannica [Last Updated On: August 28th, 2014] [Originally Added On: August 28th, 2014]