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Category Archives: Cell Therapy

Cell therapy trial offers new hope to liver disease patients

Posted: November 25, 2014 at 8:44 am

PUBLIC RELEASE DATE:

24-Nov-2014

Contact: Jen Middleton jen.middleton@ed.ac.uk 44-131-650-6514 University of Edinburgh @uniofedinburgh

Liver disease patients could be helped by a new cell therapy to treat the condition.

Researchers from the University of Edinburgh have received funding to start testing the therapy in patients within the next year.

It will be the world's first clinical trial of a new type of cell therapy to treat liver cirrhosis, a common disease where scar tissue forms in the organ as a result of long-term damage.

The Edinburgh team has received funding from the Medical Research Council and Innovate UK to investigate the disease, which claims 4000 lives in the UK each year.

The only successful treatment for end-stage liver cirrhosis at present is an organ transplant. The new therapy is based on a type of white blood cell called a macrophage, which is key to normal repair processes in the liver.

Macrophages reduce scar tissue and stimulate the liver's own stem cells to expand and form into healthy new liver cells.

Scientists will take cells from the blood of patients with liver cirrhosis and turn them into macrophages in the lab using chemical signals.

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Cell therapy trial offers new hope to liver disease patients

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American Spine Launches Plasma Rich Platelet Therapy and Stem Cell Therapy Treatments

Posted: November 25, 2014 at 8:42 am

Frederick, Maryland (PRWEB) November 25, 2014

American Spine is a practice on the cutting edge, committed to providing the latest, most effective, and innovative treatments for its patients. As part of this philosophy, American Spine joins the excitement surrounding Regenerative Medicine, a modern and progressive field of orthopedics and sports medicine. Regenerative Medicine involves the application of biological therapy treatments that enhance the body's ability to heal itself.

Dr. Sandeep Sherlekar, M.D., an owner and physician at American Spine, comments: "PRP and Stem Cell Treatments are revolutionary regeneration options for now and the future."

The major benefit of PRP and Stem Cell Therapy Treatments is the use of the patient's own whole blood, bone marrow stem cells and adipose stem cells, thus eliminating the risk of rejection or infection from other donors. These treatments are increasing in popularity as an alternative to other more invasive techniques in treating ailments such as: Muscle Tears, Meniscus and ACL Injuries, Tennis and Golf Elbow, Patellofemoral Pain Syndrome, various types of Tendonitis, Plantar Fasciitis, Spine Disease with either Degenerative Disks or Annular Tearing, Osteoarthritis in the joints and many more. They are used as a way to speed healing after other methods of treatment or to aid in the healing of resistant, long lasting injuries.

The blood and/or stem cells are harvested from the patient and are then prepared using state-of-the-art technologies. The preparation of PRP allows for a platelet sample that is 5 times more concentrated with platelets than normal blood. Similarly, the preparation of the patient's stem cells produces a much higher concentration of stem cells, both of which are essential in the healing process. The PRP and/or stem cells are then injected back into the patient's injured or degenerated tissues under guided imaging. The potential complications of such treatments are similar to those associated with regular joint injections.

American Spine stringently follows the FDA guidelines for the clinical use of blood and stem cells. We do not expand, reproduce or grow anything within a culture.

If you are interested in learning more about these treatments as a method to your own healing process or that of your patients, please visit the following link: http://www.americanspinemd.com/blog/platelet-rich-plasma-prp-and-autologous-stem-cell-treatment or call our offices to request additional information about these revolutionary therapies. We are offering a free consultation for new patients who are considering these treatments. The individual patient's treatment protocol will be formulated and discussed during the consultation.

At American Spine, our multidisciplinary team of physicians treat each patient's individual needs. Using the latest techniques and state-of-the-art equipment to diagnose pain, our practitioners determine a plan to meet each patient's unique diagnosis. We have assembled the very best team of healthcare professionals who can most effectively help our patients with a compassionate and personalized approach. We have 10 Maryland locations and one location in Gettysburg, PA to service your individual needs.

Contact Information: American Spine 1050 Key Parkway, Suite 104, Frederick, MD 21702 ph: 240-629-3939 http://www.americanspinemd.com

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American Spine Launches Plasma Rich Platelet Therapy and Stem Cell Therapy Treatments

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Leah Still to undergo stem cell therapy

Posted: November 25, 2014 at 8:42 am

CINCINNATI -- The daughter of a Cincinnati Bengal who has already been through so much has another big day ahead of her.

Leah Still -- Devon Stills daughter -- will undergo a stem cell transplant procedure on Tuesday. The stem cell treatment is an effort to regenerate her bone marrow and stem cells.

Still flew to Philadelphia Monday to be with Leah. They went shopping at a mall.

The smile you have after shutting down the mall, literally. This girl had security and the... http://t.co/HHWtLhf4pf pic.twitter.com/QFRMJsdlCX

Leah was diagnosed with stage 4 neuroblastoma in June. She had surgery to remove a tumor from her abdomen in September, followed by chemotherapy to try to remove the cancer from her bone marrow.

She has already been treated with a round of chemotherapy and radiation.

Devon Still said the family hopes that will be her only round of chemo and radiation but that it depends on how her results come back. He said it will take four to six weeks to determine if more treatments are necessary.

Follow Devon Still's updates on Twitter at @Dev_Still71

See a photo gallery from Leah's visit to Cincinnati.

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Leah Still to undergo stem cell therapy

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UCLA Researchers Unlock Protein Key to Harnessing Regenerative Power of Blood Stem Cells

Posted: November 25, 2014 at 8:42 am

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Newswise In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member, Dr. John Chute, UCLA scientists have for the first time identified a unique protein that plays a key role in regulating blood stem cell replication in humans.

This discovery lays the groundwork for a better understanding of how this protein controls blood stem cell growth and regeneration, and could lead to the development of more effective therapies for a wide range of blood diseases and cancers.

The study was published online November 21, 2014 ahead of print in the Journal of Clinical Investigation.

Hematopoietic stem cells (HSCs) are the blood-forming cells that have the remarkable capacity to both self-renew and give rise to all of the differentiated cells (fully developed cells) of the blood system. HSC transplantation provides curative therapy for thousands of patients annually. However, little is known about the process through which transplanted HSCs replicate following their arrival in human bone marrow. In this study, the authors showed that a cell surface protein called protein tyrosine phosphatase-sigma (PTP-sigma) regulates the critical process called engraftment, meaning how HSCs start to grow and make health blood cells after transplantation.

Mamle Quarmyne, a graduate student the lab of Dr. Chute and first author of the study, demonstrated that PTP-sigma is produced (expressed) on a high percentage of mouse and human HSCs. She showed further that genetic deletion of PTP-sigma in mice markedly increased the ability of HSCs to engraft in transplanted mice.

In a complementary study, she demonstrated that selection of human blood HSCs which did not express PTP-sigma led to a 15-fold increase in HSC engraftment in transplanted immune-deficient mice. Taken together, these studies showed that PTP-sigma suppresses normal HSC engraftment capacity and targeted blockade of PTP-sigma can substantially improve mouse and human HSC engraftment after transplantation.

Chute and colleagues showed further that PTP-sigma regulates HSC function by suppressing a protein, RAC1, which is known to promote HSC engraftment after transplantation.

These findings have tremendous therapeutic potential since we have identified a new receptor on HSCs, PTP-sigma, which can be specifically targeted as a means to potently increase the engraftment of transplanted HSCs in patients, said Chute, senior author of the study and UCLA Professor of Hematology/Oncology and Radiation Oncology. This approach can also potentially accelerate hematologic recovery in cancer patients receiving chemotherapy and/or radiation, which also suppress the blood and immune systems.

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UCLA Researchers Unlock Protein Key to Harnessing Regenerative Power of Blood Stem Cells

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genucel – Intensive New Stem Cell Eye Therapy Treatment …

Posted: November 24, 2014 at 8:45 am

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genucel - Intensive New Stem Cell Eye Therapy Treatment ...

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New Stem Cell Treatment Found To Cure 'Bubble Baby' Disease

Posted: November 24, 2014 at 8:43 am

Chuck Bednar for redOrbit.com Your Universe Online

A new stem cell gene therapy developed by researchers at UCLA is set to begin clinical trials early next year after the technique reportedly cured 18 children who were born without working immune systems due to a condition known as ADA-deficient Severe Combined Immunodeficiency (SCID) or Bubble Baby disease.

The treatment was developed by Dr. Donald Kohn, a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and his colleagues, and according to the university, it is able to identify and correct faulty genes by using the DNA of the youngsters born with this life-threatening condition.

Left untreated, ADA-deficient SCID is often fatal within the first year of a childs life, reports Peter M. Bracke for UCLA. However, after more than three decades of research, Dr. Kohns team managed to develop a gene therapy that can safely restore the immune systems of children with the disease by using their own cells and with no noticeable side effects.

All of the children with SCID that I have treated in these stem cell clinical trials would have died in a year or less without this gene therapy, instead they are all thriving with fully functioning immune systems, Dr. Kohn, who is also a professor of pediatrics and of microbiology, immunology and molecular genetics, said in a recent statement.

Children born with SCID have to be isolated in a controlled environment for their own safety, because without an immune system, they are extremely vulnerable to illnesses and infections that could be deadly. While there are other treatments for ADA-deficient SCID, Dr. Kohn noted that they are not always optimal or feasible for many children. The new technique, however, provides them with a cure, and the chance to live a full healthy life.

SCID is an inherited immunodeficiency that is typically diagnosed about six months after birth, the researchers said, and children with the condition are so vulnerable to infectious diseases that even the common cold could prove fatal to them. This particular form of the condition causes cells to not create ADA, an enzyme essential for the production of the white blood cells which are a vital component of a healthy, normally-functioning immune system.

Approximately 15 percent of all SCID patients are ADA-deficient, according to the university, and these youngsters are typically treated by being injected twice per week with the required enzyme. This is a process that must continue throughout a patients entire life, and even then it doesnt always work to bring their immune systems to optimal levels. Alternately, they could undergo bone marrow transplants from matched siblings, but those matches are rare and the transplanted cells themselves are often rejected by the childs body.

Dr. Kohn and his colleagues tested two therapy regimens on 18 ADA-deficient SCID over the course of two multi-year clinical trials starting in 2009. During the trials, the blood stem cells of the patients were removed from their bone marrow and genetically modified in order to correct the defect. All 18 of the patients were cured.

The technique used a virus delivery system first developed in Dr. Kohns laboratory in the 1990s a technique which inserts the corrected gene that produces the ADA into the blood forming stem cells in the bone marrow. The genetically corrected blood-forming stem cells will they produce the T-cells required to combat infections.

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New Stem Cell Treatment Found To Cure 'Bubble Baby' Disease

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Stem Cell Therapy: Dr. Roberta Shapiro – A NY Physician's Path to Panama – Video

Posted: November 22, 2014 at 3:46 pm


Stem Cell Therapy: Dr. Roberta Shapiro - A NY Physician #39;s Path to Panama
Special Guest Speaker, Roberta F. Shapiro DO, FAAPM R speaks about: A New York Doctor #39;s Path to Panama at the Stem Cell Institute #39;s Stem Cell Therapy Publi...

By: http://www.cellmedicine.com

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Stem Cell Therapy: Dr. Roberta Shapiro - A NY Physician's Path to Panama - Video

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NeoStem (NBS) Stock Plummets Today on Disappointing Cardiac Stem-Cell Therapy Data

Posted: November 18, 2014 at 2:47 pm

NEW YORK (TheStreet) -- Shares ofNeoStem (NBS) plummeted 25.52% to $5.05 in late morning trading Tuesdayafter the biotech company announced poor results from a trial of its proprietary cardiac stem-cell therapy NBS10.

NBS10, which used to be called AMR-001, missed two primary endpoints in the study to test the therapy's efficacy.The stem-cell therapy comesfrom a patient's own bone marrow and is injected into patients after a heart attack. The stem cells are then supposed to help blood flow and build cardiac muscle.

NeoStem's trial used non-invasive imaging to monitor blood flow through the heart six months after a one dose of NBS10 or a placebo. The study showed no difference between NBS and placebo, NeoStem said.

Must Read:NeoStem's Stem Cell Therapy Fails Mid-Stage Heart Attack Study

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NeoStem (NBS) Stock Plummets Today on Disappointing Cardiac Stem-Cell Therapy Data

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Stem Cell Therapy for Labrador Retriever with Ruptured Tendon – Video

Posted: November 17, 2014 at 7:46 pm


Stem Cell Therapy for Labrador Retriever with Ruptured Tendon
Marc Smith DVM of Natchez Trace Veterinary Services and Pet-Tao Pet Foods explains how he utilizes VetraGenics Stem Cell Therapy to regenerate tissue and heal the tendon.

By: Marc Smith

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Stem Cell Therapy for Labrador Retriever with Ruptured Tendon - Video

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Authorized MFIII (MF3) – Cell Placenta Therapy For Anti-Aging

Posted: November 16, 2014 at 2:42 pm

You no longer have to be Rich and famous to experience the Profound Healing effects and Intense Revitalizing and Anti-Aging benefits of MFIII (MF3) Live Cell Therapy - the best anti-aging product available in the world! Thanks to Swiss innovation and Technology, this amazing anti-aging product is now available for the first time in 70 years, and some refer to this scientific breakthrough in anti-aging and looking young as the Stem Cell in a Capsule.

Whether you are sick or experiencing chronic fatigue or just seeking the best Anti-aging and Skin Beauty supplement, everyone will benefit from the rejuvenation and regeneration of MFIII of Switzerland Live Cell Therapy. Best of all, it's acompletely Natural and Safe anti-aging solution, facilitatating and enhancing the body's ability to heal itself naturally, free from any side effects.

At last, you can feel younger, reduce cellular aging and feel full of vitality, energy, and dynamism in around 3-6 weeks with MFIII Switzerland hi-tech oral supplement formulation. MF III ( MF3) Sheep and Vegetal Placenta helps to awaken dormant cells inside the body, thereby enhancing the expression and function of existing cells, revitalizing and regenerating old and malfunctioning cells. This amazing anti-aging supplement offers what vitamins, minerals, hormones, chemicals and other typical treatments can't to worn out cells. It facilitates the processes and actual requirements for cellular functioning, mandatory for aged, hurt or sick organs and tissues to fix and regenerate, therefore providing amazing age-defying, health beauty benefits at the very same time.

Cell Treatment (or Live Cell Therapy) was first invented in an injectible form by Swiss surgeon Dr Paul Niehans in 1931. As you'll soon learn: Cell Therapy is essentially the forerunner of the better-known Human Stem Cell Therapy, which was invented in the 1960s based mostly on the principle of Cell Therapy.

Due to their intense health and beauty benefits but exceedingly high cost, Cell Therapy injections have for a while been a celebrity secret in protecting a young appearance and supporting critical health problems. Pope Pius XII was so happy with the treatment that he inducted Dr Paul Niehans, the deviser of Cell Therapy, into the Papal Academy of Science, making him the successor to the late Sir Alexander Fleming, the discoverer of penicillin.

Many celebrities, presidents and members of the Swiss Soccer World Cup team have benefited from Cell Therapy. President Eisenhower, Prime Minister Winston Churchill, and French General De Gaulle received it to maintain their powers of concentration and their physical endurance. Adenauer credited live cell therapy with giving him the energy to guide the Republic of Germany though he was more than ninety years old.

Charlie Chaplin claimed it enabled him to marry again and father kids after age seventy. Exclusive hospitals for the wealthy & famous in Switzerland have administered the Anti-Aging Cell Therapy to both western and oriental celebs, improving and lengthening their vigor and conserving their young appearance and capabilities.

Actress of "Law & Order"

"There is NO compromise for quality and effectivenes. I won't settle for anything else"

European Model

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Authorized MFIII (MF3) - Cell Placenta Therapy For Anti-Aging

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