Category Archives: Cell Therapy

Beverly Hills, California (PRWEB) October 13, 2014

Top Beverly Hills and LA orthopedic doctor, Dr. Raj, is now offering platelet rich plasma therapy for sports injuries and all types of degenerative arthritis. The treatment option has recently been added to Dr. Raj's regenerative medicine therapies such as bone marrow derived stem cell procedures and amniotic derived stem cell therapies. Call (310) 247-0466 for more information and scheduling.

Platelet Rich Plasma Therapy, known as PRP for short, has been increasing in popularity due to the success shown in several research studies. There was a recent study out of HSS showing amazing outcomes for degenerative knee arthritis, with preservation of cartilage and significant pain relief. Results with rotator cuff tendonitis, tennis elbow, plantar fasciitis and knee/achilles tendonitis have also been excellent as well.

Athletes in all types of sports have benefited from PRP therapy including golf, tennis, basketball, football, baseball and more. Whether or not an athlete is professional or amateur, the PRP treatment can be instrumental in helping patients avoid surgery and get back on the field quickly.

PRP therapy at Beverly Hills Orthopedic Institute involves an outpatient procedure that begins with a simple blood draw from the patient's arm of approximately 30 to 60 millileters. The blood is placed into a centrifuge and spun rapidly for 15-20 minutes. The platelets become concentrated in the middle layer, and this is what is utilized for the platelet rich plasma therapy in Beverly Hills.

The PRP therapy is injected under sterile conditions into the painful area. Results are typically seen over the ensuing weeks. Along with the PRP treatment, Dr. Raj also offers bone marrow and amniotic stem cell therapy. Typically, the best regenerative medicine therapy option is decided upon in conjunction with the patient.

Dr. Raj is a Double Board Certified Beverly Hills and Los Angeles orthopedic surgeon, who is also an ABC News Medical Correspondent along with a WebMD expert. For those interested in PRP and stem cell therapy Beverly Hills trusts, call (310) 247-0466.

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Top Beverly Hills Orthopedic Doctor, Dr. Raj, Now Offering Platelet Rich Plasma Therapy for All Sports Injuries and ...

About cell therapy

Cell therapy is a new official direction in medicine, based on the use of regenerative potential of the adult stem cells, aimed at the treatment of a variety of serious diseases, rehabilitation of patients after injuries and fighting with the premature signs of aging. Stem cells are also considered to be the promising biological material for the creation of the prosthetic heart valves, blood vessels, trachea, they are also used as the unique biofiller for the reconstitution of bone defects and other purposes of the plastic and reconstructive surgery.

The scientists explain the regenerative mechanism of action of stem cells both by their ability to transform into the cells of blood, liver, myocardium, bone, cartilage or nervous tissue and thus restore damaged organs and also by the reovery of the functional activity of the other cells (through the so-called paracrine type) by means of the production of a variety of growth factors.

For clinical purposes, in most cases stem cells are obtained from the bone marrow and cord blood, it is also known that the amount of stem cells, sufficient for treatment, can be isolated from the peripheral blood of an adult person, but after pre-stimulation of hematopoiesis. In recent years there is an increasing number of reports worldwide on the clinical application of stem cells, derived from the placenta, adipose tissue, umbilical cord tissue, amniotic fluid, and even pulp of the milk teeth. Depending on the disease, age and condition of the patient, one or another source of stem cells may be preferred. Hematopoietic (blood-forming) stem cells are used for more than 50 years in the treatment of leukemia and lymphomas, and this treatment is commonly known as the bone marrow transplantation, but today hematopoietic stem cells, derived from umbilical cord blood and peripheral blood are more often used in the hematologic clinics of the world. At the same time, for the treatment of traumatic brain and spinal cord injuries, the stimulation of fractures and chronic wounds healing the mesenchymal stem cells are more preferred, being the precursors of the connective tissue. Mesenchymal stem cells are found in big quantity in fatty tissue, placenta, umbilical cord blood, amniotic fluid. Due to the immunosuppressive effects of mesenchymal stem cells, they are also used in the treatment of a variety of autoimmune diseases (multiple sclerosis, ulcerative colitis, Crohns disease, etc.), as well as post-transplantation complications (to prevent the rejection of the transplanted donor organ). For the treatment of cardiovascular diseases, including lower limbs ischemia, the umbilical cord blood is considered to be the most promising, as it contains a special kind of the endothelial progenitor stem cells, which can not be found in any other human tissue.

Cell therapy may be autologous (own cells are used) and allogeneic (donor cells are used). However, it is known that every nucleated cell in the human body has certain immunological characteristics (HLA-phenotype or immune passport), that is why the use of donor stem cells requires immunological compatibility. This fact determines the appropriateness of the banking of the own stem cells, frozen until the person is still young and healthy. In this aspect the human umbilical cord blood has undisputed medical and biological value as the source of several unique lines of stem cells. Collected in the first minutes of life, umbilical cord blood stem cells have the highest potential for proliferation (growth) and directed differentiation.

Stem cell therapy can be applied both intravenously like a drug, and directly into the damaged tissue. In recent years the method of intraosseous transplantation of cord blood stem cells is more widely used, contributing to the more rapid engraftment. Also a method of introducing stem cells directly into the coronary arteries (coronary heart disease, myocardial infarction) was introduced and it is called cellular cardiomyoplasty.

Cell therapy can be carried out both in monotherapy and complementary to the surgical or drug treatment.

Currently stem cells are successfully used in the treatment of about 100 serious diseases, and in some cases this is the only effective treatment.

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Cell therapy - Institute of Cell Therapy - ...

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Newswise Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health (NIH) Director's New Innovator Award that will forward revolutionary stem cell and neuro-science in medicine. The four UCLA researchers were among only 50 scientists nationwide to receive the New Innovator Award, the most of any institution represented.

Each recipient received a $2.3M award for their respective projects. These included Dr. Reza Ardehali, assistant professor of cardiology, for his research investigating novel ways to use stem cells to regenerate heart tissue; Dr. Elissa Hallem, assistant professor of microbiology, immunology and molecular genetics, for her work studying interactions between animal parasites and their hosts to foster the further understanding of human parasitic diseases; Dr. Sririam Kosuri, assistant professor of chemistry and biochemistry, for his project developing new biological system technologies to solve outstanding problems in gene regulation; and Dr. Lili Yang, assistant professor of microbiology, immunology and molecular genetics, for her work developing a new method to track special immune cells for use in new cellular therapies.

"These New Innovator Award grants are an important acknowledgement of our cutting-edge research and will help our faculty drive the revolutionary advances we are seeing in stem cell and neuro-science," said Dr. Owen Witte, professor and director of the Broad Stem Cell Research Center. "Every cellular therapy that reaches patients must begin in the laboratory with novel ideas and experiments that will lead us in new directions in medicine and ultimately improve human life. That makes these awards invaluable to our research effort."

The NIH Director'sNew Innovator Award is designed specifically to support unusually creative investigators with highly innovative research ideas at an early stage of their career. The award seeks to support exceptionally creative new scientists whose research complements ongoing efforts by NIH.

Dr. Reza Ardehali: Unlocking the Secrets to Regenerating Heart Tissue

Dr. Ardehali's cutting-edge work focuses on both human embryonic stem cells and induced pluripotent stem cells, known as human pluripotent stem cells (hPSC), to provide insights into the mechanisms involved in the differentiation and specification of heart cells. hPSC have the unique ability to become any cell type in the body. His lab recently identified several novel surface markers that can highly enrich early cardiovascular progenitor cells. When delivered into functioning human hearts that are transplanted in laboratory conditions, the progenitor cells integrate structurally and functionally into the host myocardium. These studies established the basis for future hPSC-based cardiac therapy.

Dr. Ardehali and his colleagues were also the first to directly measure limited division in the cells that make up heart muscle (cardiomyocytes), proving that cardiomyocytes divide and that such cell division is rare. This discovery resolves an important controversy over whether the heart muscle has the power to regenerate and is critical for future research that may lead to regenerating heart tissue to repair damage caused by disease or heart attack.

His 2013, California Institute for Regenerative Medicine (CIRM), the state's stem cell research agency, New Faculty Physician Scientist Translational Research Award allowed Dr. Ardehali to initiate the preclinical studies on stem cell based therapies for heart disease that were pivotal for his success in the 2014 New Innovator Award competition. The NIH grant affirms the critical success of the project-to-date, and emphasizes the creativity of Dr. Ardehali's research and its potential to have a significant impact on the creation of novel regenerative approaches to treat heart disease.

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Four UCLA Scientists Receive Prestigious Innovator Award for Pioneering Research Using Stem Cells

Michael Scott, a ViaCyte vice president, holds the VC-01 device that holds progenitor cells that will mature to make insulin and other hormones.

More than ever before, stem cell therapies appear poised to transform medicine potentially curing heart disease, diabetes and paralyzing injuries, among other ailments.

But its also clear that such innovations will be very expensive.

How the government, insurers and patients will pay for what could be a flood of these new treatments drew the attention of more than 700 biomedical and health-care executives Tuesday at the 2014 Stem Cell Meeting on the Mesa.

The annual conference, held on La Jolla's Torrey Pines Mesa, will run through Thursday. It brings together the business and academic worlds of cell therapy, including but not limited to stem cell treatments.

In California alone, 131 clinical trials are taking place with stem cells, according to Clinicaltrials.gov, a government website that tracks clinical trials. Patients are being treated for conditions such as blindness from retinal diseases, HIV, leukemia, sickle cell disease, stroke and aging of skin.

The recent proliferation of clinical trials marks great progress toward the ultimate goal of getting new treatments to patients, said stem cell researcher Jeanne Loring, who directs the Center for Regenerative Medicine at The Scripps Research Institute in La Jolla.

Its been a sea change from last year, said Loring, who is working with some colleagues in planning their own stem cell trial to treat Parkinsons disease.

Theyre developing replacement neurons grown from artificial embryonic stem cells called induced pluripotent stem cells. The process begins with cells derived from the skin of patients to be treated.

Home-grown milestone

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Stem cell treatments surging into clinic

Arthritis of shoulder; results four years after stem cell therapy by Harry Adelson, N.D.
Heavy discusses his outcome four years out from his first bone marrow stem cell treatment for his arthritic shoulders and torn rotator cuffs by Harry Adelson, N.D. http://www.docereclinics.com.

By: Harry Adelson, N.D.

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Arthritis of shoulder; results four years after stem cell therapy by Harry Adelson, N.D. - Video

Willamette Valley, Oregon and Southwest Washington (PRWEB) October 09, 2014

Local veterinary surgeon Dr. Scott Gustafson is seeking candidates to participate in an investigational study of donor stem cells for dogs with osteoarthritis. Dr. Gustafson has lectured nationally on stem cell therapy and has performed clinical stem cell therapy for seven years. The ultimate goal of this study is to determine if a single injection of donor stem cells into one or two arthritically affected joints can help reduce pain and inflammation in the treated joints.

Candidates for the current investigational study must be older than nine months, weigh more than five and a half pounds, have osteoarthritis of only one or two leg joints, have had pain or lameness for at least three months, and must not have cancer. Joints that will be included in the study and injected under anesthesia include hips, stifles, shoulders, and elbows. Dogs that may be considered must be in good health and undergo a diagnostic work up before qualifying for the study.

Dr. Gustafson and his team coordinate directly with your veterinarian to provide the most advanced veterinary care available. Surgery 4 Pets mobile surgery provides the highest level of care and surgical expertise to your pet, in the hospital of your primary care veterinarian.

In 2007 Dr. Gustafson was credentialed with Vet-Stem, Inc. in the use of Regenerative Veterinary Medicine for arthritis, ligament and tendon injuries, and joint. To date he has provided about 100 stem cell treatments for dogs.

For information about the study, please contact Michael Stewman at mwstew(at)gmail(dot)com

About Vet-Stem, Inc. Since its formation in 2002, Vet-Stem, Inc. has endeavored to improve the lives of animals through regenerative medicine. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem pioneered the use of regenerative stem cells for horses, dogs, and cats. In 2004 the first horse was treated with Vet-Stem Regenerative Cell Therapy. Ten years later Vet-Stem celebrated its 10,000th animal treated. As animal advocates, veterinarians, veterinary technicians, and cell biologists, the team at Vet-Stem tasks themselves with the responsibility of discovering, refining, and bringing to market innovative medical therapies that utilize the bodys own healing and regenerative cells.

Contact: Sue Harman Senior Manager, Clinical Trials Vet-Stem, Inc. 12860 Danielson Court, Suite B Poway, CA 92064 858-748-2004

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Surgery 4 Pets Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis

(PRWEB UK) 7 October 2014

Stem cell treatments take place in countries all around the world every day. Thousands of lives have already been saved, and advancements in this area of medicine means that future healthcare treatments look set to further prolong and improve life.

But specialist stem cell bank BioEden warn that there is a risk of thinking of stem cell therapy in terms of the future alone. 'The need to have a stem cell match is vital', says Group CEO Mr Tony Veverka. 'Without access to a stem cell match, the work of stem cell scientists could be at risk. That is the reason why BioEden was set up, to ensure that anyone could bank and have access to their own stem cells. We also wanted to ensure that the brilliant work being carried out by stem cell scientists and medical professionals could continue unhindered'.

BioEden's services are being promoted by Health Care Professionals including specialist insurance intermediaries, and dentists. This week to highlight Stem Cell Awareness week, members of their specialist teams will be on the road visiting dentists, schools and healthcare insurance companies.

'Let's make everyone aware of the opportunities they have to store their own cells during stem cell awareness week. Perhaps we need to re name it Stem Cell Self-Awareness week'.

For more information visit http://www.bioeden.com

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BioEden the specialist tooth stem cell bank plan to shake up public perception as Stem Cell Awareness week takes hold.

Stem cell therapy of a dog in the Netherlands.
One a half years later he is juming and playing after first almost not being able not walk anymore. info@fat-stem.com.

By: Fat Stem NV

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Stem cell therapy of a dog in the Netherlands. - Video

Dr. Raj Live - Stem Cell Therapy
Dr. Raj discusses benefits of stem cell therapy.

By: SPORTSDOC RAJ

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Dr. Raj Live - Stem Cell Therapy - Video