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Category Archives: Cell Therapy

Global Stem Cell Therapy Industry Pipeline Analysis 2020 – Video

Posted: June 19, 2014 at 1:45 am


Global Stem Cell Therapy Industry Pipeline Analysis 2020
Stem Cell Therapy Industry @ http://bit.ly/1qkbHjQ.

By: Ashley Harvey

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Stem cell therapy | stem cells laboratory chip osteoarthritis – Video

Posted: June 19, 2014 at 1:45 am


Stem cell therapy | stem cells laboratory chip osteoarthritis
http://www.arthritistreatmentcenter.com A 3 D lab chip for osteoarthritis... learn more next... Living human cartilage grown on lab chip In Business Standard, scientists have created the...

By: Nathan Wei

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ReNeuron well set after 'transformational' year

Posted: June 19, 2014 at 1:45 am

ReNeuron Group Quote more

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Chg: 0.12

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Date: 16:52

Stem cell treatment developer ReNeuron lost an increased 7.1m in a "transformational" year to end-March but still had plenty of cash in the bank as it moves into new cell manufacturing facility and files an investigational new drug (IND) application in the US early next year.

The AIM-listed company held cash outflow from operating activities roughly flat at 6m over the period, leaving cash, cash equivalents and bank deposits at period end of 20.92m, thanks to the 23.44m net fundraising in August 2013.

Chairman Bryan Morton said it was a transformational year for the business, both operationally and financially, as its lead stem cell therapy candidate for stroke entered Phase II clinical trials and the company began clinical development of a candidate for critical limb ischaemia.

He also noted that in both cases, and earlier-than-planned, ReNeuron gained regulatory approval to use a cryopreserved variant of its lead 'CTX' stem cell product line, which gives the treatments the potential to have "significant commercial and competitive advantages".

He confirmed the move to new cell manufacturing facility in South Wales early next year was on track, "which we believe will become a major element of ReNeurons overall value proposition".

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ReNeuron well set after 'transformational' year

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Jordans stem-cell law can guide the Middle East

Posted: June 15, 2014 at 10:50 am

In January, Jordan passed a law to control research and therapy using human stem cells derived from embryos the first such regulation in the Arab and Islamic region. I was part of the group headed by Abdalla Awidi Abbadi, director of the Cell Therapy Center at the University of Jordan in Amman, that initiated the call for the law and later drafted it. Stem-cell research is a hot topic for Jordan because of the kingdoms status as a health-care hub that draws patients from abroad. It is already one of few countries in the Middle East with regulations for protecting people who participate in clinical trials. This latest law should serve as an example to other countries in the region.

The new rules ban private companies from using human embryonic stem (ES) cells in research or therapies. Such work will be allowed only in government organizations or publicly funded academic institutions in Jordan, which have higher levels of transparency than private firms and are supervised by the health ministry and a specialized committee. The law also bans payment for donations of stem cells and eggs, and says that modified and manipulated cells are not to be used for human reproduction. There is no current research on human ES cells in Jordan; this is a pre-emptive step.

Much of the controversy and disagreement over work on stem cells worldwide arises from the different views of the major religions on the earliest stages of life. Although the use of human ES cells is opposed by the Roman Catholic Church and some Protestant denominations, it is generally supported by the Jewish community and accepted in many Muslim countries. There is no consensus on when human embryonic life begins, but the majority of Muslim scholars consider it to start 40120 days after conception and therefore hold the view that a fertilized egg up to 5days old has no soul it is not human life but biological life. So for many, there is no ethical problem in the Islamic faith with using an early embryo to produce stem cells.

All our discussions in Jordan have concluded that stem-cell research is permissible in Islam.

Such conclusions are not easy to reach. Many Muslim countries consider legislation and bioethics principles to be based on three pillars of Islamic law. The first is the Quran. The second is Sunnah, or the legislative decisions of the Prophet Muhammad. The third is ijmaa the consensus of Muslim scholars and ijtihad, the concept that every adequately qualified scholar has the right to independently solve problems. On the basis of these pillars, Iran, Saudi Arabia and Tunisia have drawn up guidelines on stem-cell research, but they are not legally binding.

Jordans stem-cell law is the product of years of discussions by committees comprising scientists, physicians, Arabic-language experts, lawyers and Muslim and Christian theologians. The issues that arose confusion between stem cells and embryonic stem cells, for instance were discussed and resolved. We consulted with both the National Committee for Science and Technology Ethics and the education ministry. The final law was approved by the council of Muslim scholars, the Majlis Al-Iftaa.

The council agreed with a 2003 decision (fatwa) by Muslim scholars that allows the use of human ES cells from permissible sources including legally produced excess fertilized eggs from invitro fertilization. The decision to ban private companies from using these cells was driven by concerns that the work would encourage termination of pregnancies, which is illegal in Jordan unless the mothers life or health is at risk. The council was clear that the new law must forbid human reproductive cloning and should not allow embryos to be created from the sperm and eggs of unmarried couples.

The distinction drawn between the various sources of stem cells earlier in the discussion process allowed the Majlis Al-Iftaa to take a more permissive approach to techniques using stem cells that are not derived from human embryos. For example, somatic-cell nuclear transfer (in which a patients DNA is transplanted into an unfertilized human egg that has no nucleus) and induced pluripotent stem cells, which are made from adult cells, can be worked on by the private sector under the new rules.

The therapeutic use of bone-marrow transplantation including transplants of blood-forming stem cells is well established in Jordan. Such procedures are already regulated by existing laws on medical practice, so the new law makes a clear distinction between these techniques and human ES-cell therapy.

The legislation not only covers all current aspects of stem-cell research and use, but also leaves room for later modification. It mandates the creation of a national committee that, among other things, will take responsibility for laying out specific regulations for stem-cell banking in accordance with international standards.

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New Stem Cell Based Treatment for COPD; Nebulized Pure PRP System Uses Blood Growth Factors That Can Trigger Healing …

Posted: June 15, 2014 at 10:48 am

Sarasota, FL (PRWEB) June 12, 2014

Nebulized Pure PRP may offer COPD sufferers a less expensive and an effective alternative to stem cell therapy. When normal injury occurs, platelets are stimulated to release growth factors, cytokines and other immune system components in what is called the inflammatory phase of healing. In the lungs, platelets can adhere to injured or inflamed endothelial cells where they start the healing process. It is believed that by increasing the number of platelets in the lungs through this method, it is possible to decrease inflammation and accelerate the healing process in the lungs. Platelets are vehicles for the delivery of growth factors (PDGF, TGF-, IGF, EGF, VEGF) that induce proliferation of fibroblasts, osteoblasts and endothelial cells, promoting and accelerating healing of hard and soft tissues.

Autologous Platelet Rich Plasma also contains fibrin, fibronectin and vitronectin that act as cell adhesion molecules for lung epithelial migration. Autologous Platelet Rich Plasma treatment has been evaluated in various medical disciplines including orthopaedics, wound healing, neurosurgery, dentistry as well as cosmetic, plastic and cardiothoracic surgery. Nebulized Pure PRP treatment holds much promise and is being researched for its applications.

This new medical advance can bring effective and affordable healthcare to many patients with COPD. It is also attractive because the patients own blood is used thus, limiting the potential for disease transmission.

Our key product differentiation is to enable the Pure PRP treatment to be applied to patients who are suffering from COPD. COPD is the most dangerous disease in the elderly, affecting more than 200 million people across the globe. COPD is considered to be the cause of about 3 million deaths annually. This is a life-threatening disease caused by many reasons such as smoking, pollution, dust, irritants, genetic disorders, etc. It is associated with the excess production of sputum and an inflammation which obstructs the airways and results in breathing problems.

Though there is no cure for COPD, the condition can be controlled with the help of treatments. Stem cell therapy which has proved to be one of the most successful treatments for many chronic health conditions like heart disease, stroke, osteoporosis, etc., has given a ray of hope in favor of COPD. Stem cells are known for their regenerative properties which help in the development of the tissues and blood cells. These cells are of two types: embryonic stem cells and adult stem cells. Embryonic stem cells can be derived from blastocyst which is a type of embryo; whereas adult stem cells are found in the bone marrow, skin, umbilical cord, placenta and many other tissues. Embryonic stem cells are derived and are grown in cell culture for research and development. But adult stem cells, once removed from the body, divide with great difficulty which makes the treatment difficult to perform. The stem cells are either from the person itself who needs it which is known as autologous stem cell or they can be received from a donor which is known as allogeneic stem cell.

Cells donated by the donor may or may not be accepted by the bodys immune system. Hence, using ones own stem cells reduces the chances of rejection. In COPD, the tissues and cells of the lungs are destroyed, which causes various types of complications. Hence, with the help of stem cell therapy, the destroyed or damaged cells can be regenerated and new lung tissues can be formed. According to the procedure followed by the International Stem Cell Institute (ISCI); San Diego, California, adipose tissue is removed from the patient and is processed with a combination of platelet rich plasma which contains growth factors that help in the process of cell multiplication and development. This helps in COPD treatment as whenever the lungs need repair, about 80% of the stem cells reach the repairing site through the circulatory system. When the blood passes through the lungs, stem cells get trapped in the space where there is damage. The stem cells then start multiplying and repairing the tissue. The recovery does not take place immediately, but improvement can be noticed in 3 to 6 months. It helps in the suppression of inflammation, improves breathing and cures many pulmonary complications. Our Nebulized Pure PRP System aims to support this proposition to treat COPD patients. Treatments run about $1,000 and insurance does not currently pay for this treatment.

Contact our office at (941) 330-8553 to find out more about how Nebulized Pure PRP can offer you relief from symptoms of COPD. Also we are at http://advancedwellness.us/blog2/nebulized-platelet-rich-plasma-prp-for-asthma-copd-and-systemic-growth-effects-in-athletics/

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Cell Therapy for Parkinson's 2 – Video

Posted: June 12, 2014 at 11:48 am


Cell Therapy for Parkinson #39;s 2
An introduction to the cell therapy research underway with eight Parkinson #39;s Disease patients at the Scripps Clinic and Scripps Research Institute in San Diego.

By: Summit4StemCell

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Cell Therapy for Parkinson's 2 - Video

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Beverly Hills Orthopedic Institute Now Offering Revolutionary Stem Cell Procedures for Hip Arthritis to Avoid Joint …

Posted: June 12, 2014 at 11:43 am

Beverly HIlls, California (PRWEB) June 09, 2014

The top stem cell doctor in Beverly Hills and Los Angeles at Beverly Hills Orthopedic Institute are now offering stem cell procedures for hip arthritis. The stem cell therapy typically provides pain relief along with being able to delay or avoid the need for joint replacement. Call (310) 438-5343 for more information and scheduling.

Dr. Raj, Medical Director at Beverly Hills Orthopedic Institute, is a Double Board Certified orthopedic doctor who has been a pioneer in stem cell therapy for musculoskeletal conditions. Several types of stem cell procedures are offered including bone marrow derived along with amniotic derived procedures.

For the bone marrow stem cell procedures, a short outpatient procedure involves harvesting bone marrow from the patient's iliac crest. The stem cells are immediately processed to concentrate the growth factors and cells, and then they are injected into the hip for pain relief and tissue regeneration.

For the amniotic derived procedures, the fluid is obtained from consenting donors after a scheduled c-section procedure. There is no fetal tissue utilized, and the fluid is processed at an FDA regulated laboratory. An immense amount of stem cells, growth factors and hyaluronic acid are present in the amniotic material.

Dr. Raj has performed a significant amount of stem cell procedures utilizing both methods for hip arthritis, with the results being stellar to date. Being Double Board Certified and a sports medicine expert, Dr. Raj also offers stem cell procedures for sports injuries such as tendonitis and ligament injuries. This includes rotator cuff tendonitis, knee injuries, elbow tendonitis and more.

Beverly Hills Orthopedic Institute is the premier stem cell clinic in Los Angeles and Beverly Hills. Dr. Raj is an ABC News Medical Correspondent and a WebMD Medical Expert. For information on how stem cell therapy can help, call Beverly Hills Orthopedic Institute at (310) 438-5343.

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Cord blood donations a rarity in fertile, charitable Utah

Posted: June 10, 2014 at 1:47 am

(Rick Egan | The Salt Lake Tribune) Doug Schmid in the lab at Utah Cord Bank, Thursday, May 1, 2014. Utah Cord Bank is pushing to expand operations, giving parents more options for banking their babies' cord blood

In 2007, the University of Utah began collecting umbilical cord blood donations for the National Cord Blood Stem Cell bank.

Two years later, it expanded, adding Utahs major labor wards to its public banking effort giving more women in this most fertile of states the opportunity to save a life or contribute to research.

Treating disease with stem cells

Cell therapy

Cell therapies involve transplanting human cells to replace or repair damaged or diseased blood, tissue or organs. Bone marrow transplants of hematopoietic (blood-forming) stem cells are the most common.

How does it work?

Hematopoietic stem cells can form mature blood cells, such as red blood cells (which carry oxygen), platelets (to stop bleeding) and white blood cells (to fight infection). In addition to treating cancer and other blood diseases, they are being tested for use with autoimmune, genetic and a host of other disorders.

Why cord blood?

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BrainStorm launches efficacy study of stem cell therapy for ALS

Posted: June 10, 2014 at 1:47 am

US BrainStorm Cell Therapeutics (OTCBB:BCLI), a developer of adult stem cell technologies for neurodegenerative diseases, said Friday that the first participants had been recruited in a Phase II study of NurOwn in amyotrophic lateral sclerosis (ALS).

The randomised, double-blind, placebo-controlled, multi-centre trial aims to examine the safety and efficacy of transplantation of Autologous Mesenchymal Stem Cells Secreting Neurotrophic Factors (MSC-NTF or NurOwn) in 48 patients with ALS. The study is being carried out at Massachusetts General Hospital (MGH) in Boston, the University of Massachusetts Memorial (UMass) Hospital in Worcester and the Mayo Clinic in Rochester.

NurOwn is BrainStorm's autologous, adult stem cell therapy technology that differentiates bone marrow-derived mesenchymal stem cells (MSC) into MSC-NTF cells, which secrete neurotrophic, or nerve- growth, factors for protection of existing motor neurons, motor neuron growth promotion, and re-establishment of nerve-muscle interaction. BrainStorm holds the rights to develop and commercialise the technology through an exclusive, worldwide licensing deal with Israeli Tel Aviv University's technology transfer company Ramot.

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What is "Stem cell therapy" for hair loss ? | Steps in PRP Treatment : TV5 News – Video

Posted: June 7, 2014 at 7:47 pm


What is "Stem cell therapy" for hair loss ? | Steps in PRP Treatment : TV5 News
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