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Category Archives: Cell Therapy

A/Professor Dr Chin on Stem Cell Therapy – Video

Posted: March 25, 2014 at 10:48 pm


A/Professor Dr Chin on Stem Cell Therapy
Interview on Bernama TV - Dr Chin Sze Piaw, Consultant Physician Cardiologist SUBSCRIBE: http://www.youtube.com/BeverlyWilshir... FACEBOOK: http://face...

By: Beverly Wilshire

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A/Professor Dr Chin on Stem Cell Therapy - Video

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Stem cell trials on tackling osteoarthritis may lead to treatment in five years

Posted: March 25, 2014 at 10:48 pm

The trials involve injecting adult stem cells derived from adipose tissue or fat into cartilage to stimulate its regeneration

Researchers in Galway predict that stem cells could be used to treat osteoarthritis within five years, following successful initial clinical trials.

The trials involve injecting adult stem cells derived from adipose tissue or fat into cartilage to stimulate its regeneration.

Osteoarthritis affects some 70 million people across the EU, and current treatment is limited to surgery or pain management.

Some 400,000 people in Ireland are affected by this most common form of human arthritis, which is characterised by the often very painful degeneration of cartilage in joints.

Successful trial NUI Galway (NUIG) scientists, who are part of a 9 million EU-funded project, have just finished the successful phase one clinical trial.

Prof Frank Barry, scientific director of NUIGs Regenerative Medicine Institute (Remedi), yesterday said the positive early results indicate a treatment was in sight.

From the clinical trials conducted so far, we have seen the first signs of finding a cure for this truly incapacitating disease which affects so many, Prof Barry said. Using the patients own stem cells we have been able to treat their diseased joints, and relieve their suffering and burden of pain.

Whilst we are still in the early stages of clinical trials, the results so far are extremely positive such that the use of stem cell therapy for osteoarthritis could become a reality for patients within the next five years, he said.

Adipose stem cells Stem cells can be harvested in large quantities from adipose tissue or fat, with minimally invasive surgery. These cells have emerged in recent years as a good alternative to stem cells derived from bone marrow, Prof Barry notes.

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Stem Cell-Derived Beta Cells Under Skin Replace Insulin

Posted: March 25, 2014 at 10:48 pm

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Newswise Scientists at University of California, San Diego School of Medicine and Sanford-Burnham Medical Research Institute have shown that by encapsulating immature pancreatic cells derived from human embryonic stem cells (hESC), and implanting them under the skin of diabetic mouse models, sufficient insulin is produced to maintain glucose levels without unwanted potential trade-offs of the technology.

The research, published online in Stem Cell Research, suggests that encapsulated hESC-derived insulin-producing cells may be an effective and safe cell replacement therapy for insulin dependent-diabetes.

Our study critically evaluates some of the potential pitfalls of using stem cells to treat insulin dependent-diabetes, said Pamela Itkin-Ansari, PhD, assistant project scientist in the UC San Diego Department of Pediatrics and adjunct assistant professor in Development, Aging and Regenerative program at Sanford-Burnham.

We have shown that encapsulated hESC-derived insulin-producing cells are able to produce insulin in response to elevated glucose without an increase in the mass or their escape from the capsule, said Itkin-Ansari. These results are important because it means that the encapsulated cells are both fully functional and retrievable.

Previous attempts to replace insulin producing cells, called beta cells, have met with significant challenges. For example, researchers have tried treating diabetics with mature beta cells, but because these cells are fragile and scarce, the method is fraught with problems. Moreover, since the cells come from organ donors, they may be recognized as foreign by the recipients immune system requiring patients to take immunosuppressive drugs to prevent their immune system from attacking the donors cells, ultimately leaving patients vulnerable to infections, tumors and other adverse events.

Encapsulation technology was developed to protect donor cells from exposure to the immune system and has proven extremely successful in preclinical studies.

Itkin-Ansari and her research team previously made an important contribution to the encapsulation approach by showing that pancreatic islet progenitor cells are an optimal cell type for encapsulation. They found that progenitor cells were more robust than mature beta cells to encapsulate, and while encapsulated, they matured into insulin-producing cells that secreted insulin only when needed.

In the study, Itkin-Ansari and her team used bioluminescent imaging to determine if encapsulated cells stay in the capsule after implantation.

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Stem Cell-Derived Beta Cells Under Skin Replace Insulin

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Replacing insulin through stem cell-derived pancreatic cells under the skin

Posted: March 25, 2014 at 10:47 pm

PUBLIC RELEASE DATE:

24-Mar-2014

Contact: Susan Gammon Ph.D. sgammon@sanfordburnham.org 858-795-5012 Sanford-Burnham Medical Research Institute

LA JOLLA, Calif., March 25, 2014 Sanford-Burnham Medical Research Institute (Sanford-Burnham) and UC San Diego School of Medicine scientists have shown that by encapsulating immature pancreatic cells derived from human embryonic stem cells (hESC), and implanting them under the skin in animal models of diabetes, sufficient insulin is produced to maintain glucose levels without unwanted potential trade-offs of the technology. The research suggests that encapsulated hESC-derived insulin-producing cells hold great promise as an effective and safe cell-replacement therapy for insulin-dependent diabetes.

"Our study critically evaluates some of the potential pitfalls of using stem cells to treat insulin-dependent diabetes," said Pamela Itkin-Ansari, Ph.D., adjunct assistant professor in the Development, Aging, and Regenerative Program at Sanford-Burnham, with a joint appointment at UC San Diego.

"We have shown that encapsulated hESC-derived pancreatic cells are able to produce insulin in response to elevated glucose without an increase in the mass or their escape from the capsule. These results are important because it means that the encapsulated cells are both fully functional and retrievable," said Itkin-Ansari.

In the study, published online in Stem Cell Research, Itkin-Ansari and her team used bioluminescent imaging to see if encapsulated cells stay in the capsule after implantation.

Previous attempts to replace insulin-producing cells, called beta cells, have met with significant challenges. For example, researchers have tried treating diabetics with mature beta cells, but because mature cells are fragile and scarce, the method is fraught with problems. Moreover, since the cells come from organ donors, they may be recognized as foreign by the recipient's immune systemrequiring patients to take immunosuppressive drugs to prevent their immune system from attacking the donor's cells, ultimately leaving patients vulnerable to infections, tumors, and other adverse events.

Encapsulation technology was developed to protect donor cells from exposure to the immune systemand has proven extremely successful in preclinical studies.

Itkin-Ansari and her research team previously made an important contribution to the encapsulation approach by showing that pancreatic islet progenitor cells are an optimal cell type for encapsulation. They found that progenitor cells were more robust than mature beta cells to encapsulate, and while encapsulated, they matured into insulin-producing cells, which secreted insulin only when needed.

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Replacing insulin through stem cell-derived pancreatic cells under the skin

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Heart Stem cell therapy – Video

Posted: March 24, 2014 at 10:41 am


Heart Stem cell therapy
Clara answers some questions regarding the stem-cell therapy she received for congenital heart disease. For more info visit: http://www.stemaid.com.

By: stemaid

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Heart Stem cell therapy - Video

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Wounded Pa. soldier seeks Chinese stem cell cure

Posted: March 24, 2014 at 10:41 am

YORK, Pa. (AP) - A York County soldier left partially paralyzed when he was shot in Afghanistan nearly two years ago is banking on stem cells to help him regain movement.

Matthew Hanes, 22, of Manchester Township will head to China in April to undergo surgery to repair part of his damaged spinal cord.

Doctors essentially will use minor surgery and stem cell therapy to build a bridge over two vertebrae that were shattered when Hanes was shot.

At the minimum Ill get at least some feeling back where I dont have it in certain places, but I could get everything back if it goes well, Hanes said.

U.S. Army Cpl. Hanes was shot while on patrol in Afghanistan in June 2012. He was left with limited use of his upper body and no use of his lower extremities.

RESEARCH: Soon after he returned to the U.S., Hanes began researching stem cell therapy as possible treatment.

Thats how he found Puhua International Hospital in Beijing, where he will fly on April 1 for the treatment. Hes slated to return stateside later that month.

Its coming up slowly now that I know its on, Hanes said.

During his research, Hanes said he found the U.S. is so far behind on stem cell research compared to some countries in Asia, such as China, and Europe.

For years, the federal government imposed tight restrictions on stem cell research until it was loosened in 2009 by President Barrack Obama.

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Wounded Pa. soldier seeks Chinese stem cell cure

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Should stem cell therapy be used in DLBCL? – Video

Posted: March 23, 2014 at 8:44 am


Should stem cell therapy be used in DLBCL?

By: Lymphoma Hub

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Should stem cell therapy be used in DLBCL? - Video

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The furor over fresh-cell therapy (which is NOT stem cell therapy)

Posted: March 23, 2014 at 8:44 am

The Philippines is the biggest market for the popular, if highly controversial, alternative treatment in Germany called fresh-cell therapy (FCT). Fresh cells derived from the fetus of an unborn lamb are injected into patients, and are said to cure a large number of illnesses.

Despite the high cost of the treatment, wealthy Filipinos are undeterred, and typically arrive in droves in a sleepy town outside Frankfurt, their hopes of being cured or rejuvenated pinned on the life of every donor sheep.

Given its renown, its no surprise that questions about the efficacy and safety of FCT has been the subject of discussions among health professionals. There have also been rumors of deaths after FCT.

The proponents of FCT in Germany, however, claim that all talk about patient deaths and questionable safety standards are unfounded, and an uncouth effort to discredit FCT so that the same medical professionals here could promote stem-cell therapy, which is allowed in the country. They deny the rumors of deaths and challenge their accusers to show proof. They also maintain that FCT is a decades-old, legitimate and safe naturopathic treatment.

Theres also a rivalry in Edenkoben between the famous clinic Villa Medica and the breakaway practice of Dr. Robert Janson-Mller, who used to work at the same clinic.

Dr. Mller now administers FCT in a hotel, which doubles as his clinic. This gave rise to talks questioning the standards of a practice that is done in a hotel, not a hospital. Some accounts also say that there have been Filipino patients fooled into believing they were bound for Villa Medica, only to find themselves in Dr. Mullers hotel.

Inquirer Lifestyle visits the two rival clinics in Germany, and we experience firsthand what FCT is all about.

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Tags: Dr. Robert Janson-Mller , Frankfurt , fresh cell therapy , Stem Cell Therapy , Villa Medica

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The furor over fresh-cell therapy (which is NOT stem cell therapy)

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Should stem cell therapy be used in DLCBL? – Video

Posted: March 22, 2014 at 12:43 am


Should stem cell therapy be used in DLCBL?
Response based on the findings of the case study presented by Prof. Marek Trnn Transcript: The question to consider is whether a stem cell transplant is su...

By: Emmet Dunne

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Should stem cell therapy be used in DLCBL? - Video

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Embryonic Stem Cell Therapy – Video

Posted: March 20, 2014 at 3:50 pm


Embryonic Stem Cell Therapy
Short fun video about Stemaid #39;s Embryonic Stem Cells Visit http://www.stemaid.com.

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