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Category Archives: Cell Therapy
California’s Stem-Cell Quest Races Time as Money Dwindles
Posted: December 12, 2013 at 11:42 pm
Californias government-run stem-cell research agency, on course to spend $3 billion in taxpayer money to find treatments for some of the worlds most intractable diseases, is pushing to accelerate human testing before its financing runs out.
For the California Institute for Regenerative Medicine, time is growing short to fund research that demonstrates the potential of stem cells to help treat everything from cancer to heart disease to spinal cord injuries.
The agency, created by voters in 2004, has given out more than half of its $3 billion from state bonds and must spend the rest by 2017. The largest U.S. funding source for stem-cell research outside the federal government, its under pressure to show results to attract new money from pharmaceutical companies, venture capitalists or even more municipal bonds.
We need to figure out how to keep them going, said Jonathan Thomas, a founding partner of Saybrook Capital LLC in Los Angeles, and chairman of the institutes board, which meets today. We could do public-private partnerships, venture philanthropy, a ballot box.
Embryonic stem cells have the potential to change into any type of cell in the body. They are among the first cells created in embryos after conception. Scientists hope they may replace damaged or missing tissue in the brain, heart and immune system.
California voters approved the bonds after President George W. Bush banned the use of federal funds for research on embryonic stem cells. Since then, other types of stem cells have been shown to act like embryonic cells, relieving some of the debate over the ethics of destroying human embryos to use the cells.
The agencys funding decisions have included a grant of $20 million to a team led by Irv Weissman at the Stanford University School of Medicine, seeking a cure for cancer.
Weissmans team is working on an antibody manufactured with stem cells that allows a cancer patients own immune system to destroy a tumor, instead of relying on toxic radiation or chemotherapy. The antibody counteracts a protein called CD47, which creates what scientists call a dont eat me shield around the cancer. Once that cloak is removed, the patients immune system recognizes the cancer and attacks the tumor, shrinking or eliminating it.
Tests on humans are to begin early next year. The antibody has already worked in mice against breast, colon, ovarian, prostate, brain, bladder and liver cancer.
Two other research projects funded by the California agency are in human trials now -- one targeting HIV, the virus that causes AIDS, and another that regrows cardiac tissue in heart-attack victims.
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UCLA Scientists Taking Stem Cell Research to Patients
Posted: December 12, 2013 at 11:40 pm
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Newswise Scientists from UCLAs Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are bringing stem cell science funded by the California Institute of Regenerative Medicine (CIRM), the state stem cell agency, directly to patients in two exciting new clinical trials scheduled to begin in early 2014. The recipients of the Disease Team Therapy Development III awards were Dr. Dennis Slamon and Dr. Zev Wainberg, whose phase I clinical trial will test a new drug that targets cancer stem cells and has been approved to begin enrolling patients in the US and Canada, and Dr. Donald Kohn, whose first-in-human trial is on stem cell gene therapy for sickle cell disease (SCD).
The announcement of the new awards came on December 12, 2013 at the meeting of the CIRM Independent Citizens Oversight Committee (ICOC) at the Luxe Hotel in Los Angeles. Dr. Owen Witte, Director of the UCLA Broad Stem Cell Research Center, highlighted that the The CIRM support demonstrates that our multidisciplinary Center is at the forefront of translating basic scientific research to new drug and cellular therapies that will revolutionize medicine.
Targeting solid tumor stem cells The Disease Team III grant to Dr. Dennis Slamon and Dr. Zev Wainberg and their US-Canadian collaborative team will support the first in human clinical trial scheduled to open in early 2014. The project builds on Dr. Slamons previous work partially funded by CIRM to develop a drug that targets tumor initiating cells with UCLAs Dr. Zev Wainberg, assistant professor of hematology/oncology and Dr. Tak Mak, director, Campbell Family Institute of the University Health Network in Toronto, Canada. Dr. Slamon, renowned for his research that led to the development of Herceptin, the first FDA-approved targeted therapy for breast cancer, is the director of clinical and translational research at the UCLA Jonsson Comprehensive Cancer Center, and professor, chief and executive vice chair for research in the division of hematology/oncology.
With investigational new drug approval from the Food and Drug Administration (FDA) and Health Canada, the Canadian governments therapeutic regulatory agency, this trial is an international effort to bring leading-edge stem cell science to patients.
We are delighted to receive this CIRM grant that will drive our translational research from the laboratory to the clinic, Slamon said, and allow us to test our targeted drug in a phase I clinical trial.
The trial is based on the evidence built over the last decade for what has become known as the cancer stem cell hypothesis. According to this hypothesis, cancer stem cells are the main drivers of tumor growth and are also resistant to standard cancer treatments. One view is that cancer stem cells inhabit a niche that prevents cancer drugs from reaching them. Another view is that tumors can become resistant to therapy by a process called cell fate decision, by which some tumor cells are killed by therapy and others become cancer stem cells. These cancer stem cells are believed to be capable of self-renewal and repopulation of tumor cells, resulting in the recurrence of cancer.
The target of the new drug is an enzyme in cancer stem cells and tumor cells called Polo-like kinase 4, which was selected because blocking it negatively affects cell fate decisions associated with cancer stem cell renewal and tumor cell growth, thus stopping tumor growth.
This potential anti-cancer drug is now ready to be tested in humans for the first time. Our goal is to test this novel agent in patients in order to establish safety and then to proceed quickly to rapid clinical development. We are excited to continue this academic collaboration with our Canadian colleagues to test this drug in humans for the first time, said Wainberg. Drs. Slamon, Wainberg, Mak and colleagues will also look for biological indications, called biomarkers, that researchers can use to tell if and how the drug is working.
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UCLA Scientists Taking Stem Cell Research to Patients
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Stem Cell Treatment and Stem Cell Therapy | Vista Stem Cell
Posted: December 9, 2013 at 12:41 pm
Stem Cell Treatment at Your Fingertips Stem cell therapy has come a long way over the last ten years, despite repeated interventions by some western governments to restrict its research. One place which has not suffered from these setbacks is China.
At our facilities in Beijing, we have been administering treatments using fetal stem cells for nearly ten years with ever improving results. Our sophisticated stem cell treatment techniques and experience ensure patients receive the highest quality therapy in the world and an alternative to existing treatments that they cannot find in their own country.
We use the strictest protocols to ensure that all our stem cells are disease-free and healthy. Most of our doctors were educated in the West and have a strong understanding of the demands of western patients.
We believe people should not have to put up with their illness when an alternative already exists. Our mission is to improve the quality of life of all our patients and enable you to gain control over your life.
View our Current Treatments section to find out more about the stem cell treatment and therapy we can provide you with.
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Stem Cell Treatment and Stem Cell Therapy | Vista Stem Cell
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Adult Stem Cell Therapy – Regenocyte
Posted: December 7, 2013 at 12:40 pm
Adult stem cells circulate throughout our bodies and act as natural healers. These cells have vast potential and limitless capabilities. For more than 40 years, adult stem cells have been used to treat cancer patients. Recent advancements in stem cell therapy have been astounding. Cells from an ill patient are being used as part of the treatment. There is no possibility of the body rejecting the new tissue formed, making stem cell treatment safe and effective in achieving positive medical outcomes. It is important to note that adult stem cell therapy is not controversial because it involves the use of a patients owntissues and NOT derived from embryos. Clinical results from cardiac, pulmonary, neurological and vascular procedures have shown that the adult stem cell procedures are as safe as traditional procedures and are complimentary to current medical practice.
Adult stem cells are extracted from the patientsbone marrow and fat(adipose). At Intercellular Sciences, the naturally occurring stem cells in the blood are cultivated into millions of RegenocyteAdult Stem Cells. The Regenocyte Stem Cells areproduced inour international treatment center and are administered into the area of need for the patient. Once injected, they stimulate tissue re-growth and greater blood flow to the affected areas. The goal of the treatment is to replace damaged cells and to promote the growth of new blood vessels and tissues in order to help the target organ function at a greater capacity. There is no risk of rejection since the Adult Stem Cells received are directly from the patient.
Regenocyte Adult Stem Cell Therapy is safe, highly effective and presents minimal risk.
To find out more today, click here or call us at (866) 216-5710
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stem cell therapy makes senile spot disappear. – Video
Posted: December 6, 2013 at 12:43 am
stem cell therapy makes senile spot disappear.
"ReLife" was founded by Professor Zhang, a well respected doctor with decades of experience in the medical field. Over the decades, "ReLife" pioneering, country leading experts have been dedicated...
By: IMC ReLife
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stem cell therapy makes senile spot disappear. - Video
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Stem Cell Therapy for Arthritis and Injuries | Regenexx Procedures
Posted: December 6, 2013 at 12:43 am
The Regenexx Procedures are a family of non-surgical stem cell and blood platelet treatments for common injuries and degenerative joint conditions, such as osteoarthritis and avascular necrosis. These stem cell procedures utilize a patients own stem cells or blood platelets to help heal damaged tissues, tendons, ligaments, cartilage, spinal disc, or bone.
Regenexx Stem Cell and Blood Platelet Procedures offer a viable alternative for individuals who are suffering from joint pain, or who may be considering elective surgery or joint replacement due to injury or arthritis. Patients avoid the lengthy periods of downtime, and painful rehabilitation that typically follow invasive surgeries.
The list below represents the most commonly treated conditions using Regenexx stem cell or platelet procedures. It is not a complete list, so please contact us or complete the Regenexx Candidate Form if you have questions about whether you or your condition can be treated with these non-surgical procedures. The type of procedure used (stem cell or blood platelet) to treat these conditions is largely dependent upon the severity of the injury or condition.
The Centeno-Schultz Clinic is theoriginalstem cell based musculoskeletal practice in the U.S., with more stem cell orthopedics experience than any other clinic. We are also physician leaders in stem cell treatments for arthritis and injuries in terms of research presentations, publications, and academic achievements.
The episode features Dr. Centeno and Dr. Hanson, along with patient Barbee James, who required stem cell treatment after a failed micro fracture and continued problems following traditional knee surgery. The episode provided a nice overview of a Regenexx-SD (same-day) stem cell procedure for Barbees knee cartilage damage.
On February 28, 2013 Seattle King TV featured Regenexx patient Paul Lyon, who underwent a Regenexx-SD knee procedure in our Broomfield clinic. The story looks at his results and includes an interview with Dr. Christopher Centeno, along with footage in our advanced lab where stem cells are processed as part of the procedure.
Regenexx Network Physician Dr. Mayo Friedlis (Washington D.C. area) is featured in this recent news story about stem cell therapy, which explores the Regenexx-SD stem cell procedure and a very active seniors outcome following his knee stem cell injection.
Our Pittsburgh, PA. Regenexx Network Provider, Rehabilitation and Pain Specialists, was recently featured in a news story about treating a patients knee pain with stem cells. The patient returned to their clinic for this procedure after experiencing success with the stem cell treatment he received on his other knee.
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Stem Cell Therapy for Arthritis and Injuries | Regenexx Procedures
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"VAMPIRE FACELIFT STEM CELL and PRP THERAPY" www.CLINICell.com – Video
Posted: December 4, 2013 at 4:42 pm
"VAMPIRE FACELIFT STEM CELL and PRP THERAPY" http://www.CLINICell.com
By: ClinicellTech
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"VAMPIRE FACELIFT STEM CELL and PRP THERAPY" http://www.CLINICell.com - Video
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Aegean Process (Stem Cell Therapy with PRP) – Video
Posted: December 4, 2013 at 4:42 pm
Aegean Process (Stem Cell Therapy with PRP)
By: sapardue
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Aegean Process (Stem Cell Therapy with PRP) - Video
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Stem Cell Therapy Injections – Video
Posted: November 30, 2013 at 1:44 am
Stem Cell Therapy Injections
Stem Cell therapy, is one form of Comprehensive Prolotherapy available for arthritis treatment, and other chronic pain conditions at Caring Medical and Rehab...
By: Rob C
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Stem Cell Therapy Injections - Video
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Cell Therapy – American Cancer Society
Posted: November 29, 2013 at 7:47 am
Other common name(s): cellular therapy, fresh cell therapy, live cell therapy, glandular therapy, xenotransplant therapy
Scientific/medical name(s): none
In cell therapy, processed tissue from the organs, embryos, or fetuses of animals such as sheep or cows is injected into patients. Cell therapy is promoted as an alternative form of cancer treatment.
Available scientific evidence does not support claims that cell therapy is effective in treating cancer or any other disease. Serious side effects can result from cell therapy. It may in fact be lethalseveral deaths have been reported. It is important to distinguish between this alternative method involving animal cells and mainstream cancer treatments that use human cells, such as bone marrow transplantation.
In cell therapy, live or freeze-dried cells or pieces of cells from the healthy organs, fetuses, or embryos of animals such as sheep or cows are injected into patients. This is supposed to repair cellular damage and heal sick or failing organs. Cell therapy is promoted as an alternative therapy for cancer, arthritis, heart disease, Down syndrome, and Parkinson disease.
Cell therapy is also marketed to counter the effects of aging, reverse degenerative diseases, improve general health, increase vitality and stamina, and enhance sexual function. Some practitioners have proposed using cell therapy to treat AIDS patients.
The theory behind cell therapy is that the healthy animal cells injected into the body can find their way to weak or damaged organs of the same type and stimulate the body's own healing process. The choice of the type of cells to use depends on which organ is having the problem. For instance, a patient with a diseased liver may receive injections of animal liver cells. Most cell therapists today use cells taken from taken from the tissue of animal embryos.
Supporters assert that after the cells are injected into the body, they are transported directly to where they are most needed. They claim that embryonic and fetal animal tissue contains therapeutic agents that can repair damage and stimulate the immune system, thereby helping cells in the body heal.
The alternative treatment cell therapy is very different from some forms of proven therapy that use live human cells. Bone marrow transplants infuse blood stem cellsfrom the patient or a carefully matched donorafter the patients own bone marrow cells have been destroyed. Studies have shown that bone marrow transplants are effective in helping to treat several types of cancer. In another accepted procedure, damaged knee cartilage can be repaired by taking cartilage cells from the patient's knee, carefully growing them in the laboratory, and then injecting them back into the joint. Approaches involving transplants of other types of human stem cells are being studied as a possible way to replace damaged nerve or heart muscle cells, but these approaches are still experimental.
First, healthy live cells are harvested from the organs of juvenile or adult live animals, animal embryos, or animal fetuses. These cells may be taken from the brain, pituitary gland, thyroid gland, thymus gland, liver, kidney, pancreas, spleen, heart, ovaries, testicles, or even from whole embryos. Patients might receive one or several types of animal cells. Some cell therapists inject fresh cells into their patients. Others freeze them first, which kills the cells, and they may filter out some of the cell components. Frozen cell extracts have a longer "shelf life" and can be screened for disease. Fresh cells cannot be screened. A course of cell therapy to address a specific disease might require several injections over a short period of time, whereas cell therapy designed to treat the effects of aging and "increase vitality" may involve injections received over many months.
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Cell Therapy - American Cancer Society
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