Category Archives: Diabetes

LONDON, April 27, 2017 /PRNewswire/ -- Diabetes management is on the verge of being disrupted by innovative technologies such as artificial pancreas, non-invasive glucose monitoring sensors, wearables, apps, and inhalable insulin. This research study captures all the innovative developments across the segments of wellness, diagnosis, monitoring, and therapy of the diabetes care continuum, covering the global market.

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Diabetes remains one of the top causes of mortality, and health expenditure on the disorder and its complications is set to rise 19% annually until 2040, to reach $802 billion. Beyond the traditional focus and high-interest areas of monitoring and therapy, rising diabetes prevalence and costs are resulting in the focus gradually shifting to preventing diabetes, and on the overall wellbeing of diabetics and pre-diabetics, resulting in the highest double-digit growth of the wellness segment. Diagnosis, however, remains a neglected aspect of diabetes and novel approaches may be necessary to improve screening and diagnosing patients earlier to save on long-term costs. Monitoring developments that help improve the quality of life of diabetics include blood glucose monitoring tech advances (traditional glucometers and also semi-invasive, implants, and non-invasive continuous glucose monitoring systems), data analytics support, care delivery support, and overall diabetes management support in the form of apps, telehealth, and insulin dosing calculation support. Therapy, the largest segment, is also seeing several improvements in terms of better drugs, combination drugs, better insulin forms, and better delivery mechanisms. Of course, the main development in this segment is that of artificial pancreasthere is one commercially available system and several being developed with varying approaches and features. The other notable "permanent cure" approach is cell therapy involving regenerative medicine techniques with variations in the approaches for transplantation.

The study provides an exhaustive coverage of the overall diabetes ecosystem, with strong focus on startups, apart from the existing stakeholders. It also analyzes the role that technology giants such as Alphabet (ne Google) and IBM are playing in the diabetes space. An overview of several innovative diabetes care delivery models from across the world is also included. The study would be valuable for diabetes stakeholders to chart out their strategies for future collaborations and partnerships, while keeping a watchful eye on the competition.

Key questions this study will answer: How is the diabetes burden evolving across the globe? How are market forces and trends shaping the diabetes market and the segments of wellness, diagnosis, monitoring, and therapy? What gaps in diabetic care need to be filled to address the unmet needs of diabetics? What are the technological developments in the industry that attempt to address such unmet needs? How have some care models perfected diabetes management, catering to local needs? What are some future perspectives for the industry? Download the full report: https://www.reportbuyer.com/product/4842301/

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Future of Diabetes Care Paradigms, Forecast to 2022 - Yahoo Finance - Yahoo Finance

(WJBK) - In just over two weeks, Miss Michigan Krista Ferguson will be traveling to Las Vegas to compete for the title of Miss USA.

While she has the spotlight, she's using the attention to raise awareness about diabetes. She was diagnosed with Type 1 diabetes two years ago.

Type 1 diabetes, also known as juvenile-onset, is where the body's immune system destroys the cells that release insulin, versus Type 2 diabetes in which your body can't use insulin the right way. Type 2 typically develops in adulthood.

Krista is giving herself about four shots every day, as well as pricking her finger multiple times to check her blood sugar. She also keeps a patch on her leg that continuously checks her blood sugar, and she gets alerts on her phone if her levels are changing too quickly.

Krista wants others to know that your illness doesn't define you.

"It may be a part of you but it will never stop you from conquering your dreams and achieveing your goals," she says.

You can watch Krista compete in the Miss USA competition right here on FOX 2 on May 14, 2017 at 7 p.m.

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Miss Michigan raising awareness about diabetes - Fox 2 Detroit

COLUMBIA Verna Laboy's paternal grandmother lost both legs to diabetes complications. Very recently, one of her cousins lost a leg also to diabetes. Yet another cousin is on dialysis, a complication of the same disease.

"This is personal for me," she says.

She doesn't pretend to be an expert that's not where the passion comes from. She, herself, was "on the fast track" to diabetes and has found it hard to stick with an exercise or diet.

All of that has made Laboy a passionate force behind Live Well By Faith, a wellness program launched one year ago through the Columbia/Boone County Health and Human Services Department for black churches in Boone County.

Data from a county-wide survey in 2013 showed that of the 9,300 people living with diabetes in Boone County, black people were four times more likely to die from complications related to the disease than their white counterparts. Nationally, black women are just under two times more likely than white women to die from diabetes complications, while black men are about one and a half times more likely than white men to die from diabetes complications, according to the Centers for Disease Control and Prevention.

Type 2 diabetes the more common form of the chronic disease occurs when the level of blood glucose (sugar) in a person's body is higher than normal because insulin ceases to be produced properly, according to theAmerican Diabetes Association. As a result, the body's cells are starved for energy and the eyes, kidneys, nerves and heart can be effected. Factors associated with diabetes include obesity, a family history of the disease and race and ethnicity.

Verna Laboy saves leftover food April 2 after the Live Well By Faith cooking class. Laboy runs the Live Well By Faith wellness program through St. Luke United Methodist Church in Columbia, which aims to address health disparities in minority communities through church programs.

Laboy, a self-proclaimed "health evangelist" and community activist, has been working with black churchgoers since April 2016 to educate people about the consequences of unhealthy lifestyles, to encourage healthy eating and to provide programsfor long-term success in health management.

"Food is important to this culture, and it's cooked the wrong way. It's a lethal digestion," Laboy said. "It's an addiction that needs to be addressed, a very unhealthy addiction. We need to increase our health literacy."

Laboy uses the word "bulldozer" to describe how she's paving the way towards bringing down the rates of diabetes and heart disease among blacks in Boone County.

"I don't have a health background. I'm not a personal trainer. I'm not a nutritionist," she said.

Her own struggle to change her lifestyle has been a source of insight.

"But I've been on this journey for years, unable to stay consistent," she said.

She and other "health ministers" at the Live Well By Faith-accredited churches are "looking for people that are dealing with the challenges themselves to adopt (healthy) behaviors and see the changes and take people on the journey with them," she said.

Laboy enthusiastically and passionately evangelizes on a healthy lifestyle.

"Verna's not doing the work," she said, slipping into third person, as she often does. "You have to do the work. This is your church. This is your congregation. This is your family. This is your life."

Diabetes can lead to high blood pressure, heart disease, amputations and death if not managed well, according to the American Diabetes Association.

Lifestyle factors and genetics are the primary influences of type 2 diabetes, according to a study published in 2012. Type 2 diabetes involves insulin resistance and declining insulin production and components of the disease include physical inactivity, sedentary lifestyle, cigarette smoking and a generous consumption of alcohol.

Maintaining a healthy diet for the prevention or treatment of diabetes combined with physical activity is associated with lowered risks of diabetes, according toa study published by the Journal of Education and Health Promotion. Eating smaller serving sizes and cutting calories improves insulin sensitivity, and regular physical activity helps with weight loss and may also decrease blood pressure.

Increasinghealth literacy entails learning about what types of foods are recommended for healthful living, what types of food to avoid and fitness.Focusing meal planning around nutrient dense foods such as vegetables, beans, whole grains, fruit, non-fat dairy, fish and lean meats is one way to decrease the risk of diabetes, according to theAmerican Diabetes Association.

But the church is an especially important institution for many black Americans.

From left, Frances Logan, Shae Brown and Mary B. Warren wash their hands during the Live Well By Faith cooking class April 2 in Columbia. Each attendee washed their hands for 20 seconds, which was a technique they reviewed at the start of the workshop.

Annabelle Simmons, a health minister at St. Luke United Methodist Church, joined the Live Well By Faith team . After she took a healthy lifestyle class through the program, she said her eyes were opened about health.

But she wasn't sure exactly which of the possible Life Well by Faith courses she would teach.

There it was: "Cooking Matters." She thought to herself, "I know how to cook," but had to become certified to teach it. That entailed learning about how to hold a knife properly, how to slice correctly, among other kitchen skills.

The healthy cooking and eating topics changed her habits: learning how to read food labels, how much food is in a serving, the calorie count, the protein count, etc. "And now, every time I go shopping, I'm looking at the labels, so I know it works," she said.

The class also teaches people how to cook healthy food on a budget, Laboy said: "They can see how cheap they can cook good food, healthy food."

In addition to what she learned in "Cooking Matters," Simmons also learned how to take a blood pressure reading, which she does on Sundays free if church members ask her to do so. The health ministers at St. Luke also signed off on a water policy, requiring that water be offered with every meal offered at a church event.

"People were going, 'But I want punch, I want coffee,'" Simmons said.

A "no fried foods" policy is also in place.

And yet, people still gather around the table.

"We get to fellowship with one another around food, preparing the food together," Simmons said.

Dee Campbell-Carter, a lifestyle coach for the health ministry at Friendship Missionary Baptist Church, said the church will start a "Cooking Matters" class later this year. The health ministry at Friendship Baptist offers blood pressure checks every second and fourth Sunday before and after service lets out as well as "SweatSuit Sundays," when the congregation stops in the middle of service to do high- and low-impact exercises to gospel music.

"The thing we're doing is building a faith community that's cross-pollinating," Laboy said. This means that if a class is offered at one church, all the other churches are invited to send participants.

Dee Campbell-Carter, left, and Dorothy Slaughter tend to a garden plot April 17 at Friendship Baptist's community garden. Campbell-Carter is in charge of the garden, which came to fruition in January.

As the sun set last week, Campell-Carter strolled between garden plots behind Friendship Missionary Baptist filled with budding greens, tomatoes and peppers while bees hovered over dandelion-covered grass. Campbell-Carter and community member Dorothy Slaughter tilled the soil, pulling weeds and watering mustard and collard greens and kale.

The garden is called "Friendship Gardens," and the food harvested in the plots will be used in the "Cooking Matters" class when it begins.

Half-built garden beds lay ready for the next stage: being raised on stilts for planting. They will be waist high to accommodate children or those who are wheelchair bound, Cambell-Carter said.

The garden is a placewhere church memberscan grow healthy produce to take home and cook.

Cambell-Carter described Slaughter as the go-to gardener. She taught the community how to dig weeds out from their root with a simple tools like a plastic knife, and that coffee grounds are a good fertilizer and deterrent for some pests.

Calvin Miles, another member of Friendship Baptist Church, is the handy man on site. He put the finishing touches on the community garden sign his son painted that will stand over their "harvest trailer." He also built the raised flats for youth or those with disabilities.

Healthy food fits with his spiritual life, Miles said: "Body, mind and spirit. They all come together."

Calvin Miles paints Friendship Missionary Baptist's Friendship Garden sign on April 17. Miles' son painted the majority of the sign, while Miles added the finishing touches.

"When I see things like (Friendship Gardens) take offit's just everything," Laboy said.

But not every health ministry takes root as easily nor does every program.

Paula Williams chaired the board for the Boone County Minority Health Network until it disbanded last year. The network began in 2005 with the purpose of addressing health disparities. It ultimately died due to lack of funding.

"There was no full-time, dedicated staff to keep up with the grant writing," Williams said.

Live Well By Faith is on a two-year grant from the Boone County Commission, and Laboy is optimistic about getting it renewed. "I'm letting anyone out there that's doing this kind of work know that Verna is available to take this to the next level," she said.

There's one year left on the grant. Then, the Columbia/Boone County Department of Public Health and Human Services will re-apply. "We are just getting started," Laboy said.

She recognizes that it takes time to change a culture.

"We have to make different choices," she said. "We're living longer. Do you want to live in a nursing home? Do you want illness to take you out in such a way where someone who doesn't want to take care of you is forced to take care of you? It's a tough conversation to have, but someone has to put it out there."

Churches around Boone County are having that conversation. Laboy hopes "Cooking Matters" will be offered in 15 African-American churches in the upcoming year. Urban Empowerment Ministries has a Weight Watchers program with 22 members representing five different church communities.

Five other churches are interested in the upcoming "Eat Healthy, Be Active" program, Laboy said. She and six trained lifestyle coaches from those health ministries will be meeting to talk about bringing the curriculum to those five churches. The Columbia/Boone County Department of Public Health and Human Services has a "Shazzy Fitness" program that brings community members together to work out to gospel music.

"These are small ways we're chipping away at the health literacy and health consciousness of people," Laboy said.

Dorothy Slaughter removes weeds from her garden plot on the evening of April 17. The garden, a part of the Live Well By Faith program at Friendship Missionary Baptist Church, is open to community members to grow healthy produce to use in their meals.

"This is the hardest work I've ever done," Laboy said. "And it's taking care of myself. Why is that so hard to do? Because we're going against the grain; it's going against the culture," she said. "Great-grandma made the biscuits this way. Grandma made the greens this way. Mom makes the cobbler this way. So our tastes have adjusted, but it's killing us."

There are healthier ways of doing things, Simmons said. "You start developing a habit of being healthy rather than choosing the cake. It's been a long time since I've had cake, now. I want cake; I love cake! But it's an unhealthy choice."

Laboy shared similar sentiments. "You've got to be able to tell yourself no," she said.

"This is a lifestyle transformation change for me and I have to do it. If no one else does it, Verna has to show up for Verna."

Laboy shares her experiences on the Live Well By Faith Facebook page regularly, reminding those who are on the journey with her that they can succeed even if some days are hard. "Victory I make it to the gym this morning and boy was it a struggle. I wanted to quit!" she shared in a recent post.

"Setbacks are set-ups for a come back!" she wrote in an earlier post.

Campbell-Carter faced a setback as well. "I had to creatively regroup my workout plan when my (Activity and Recreation Center) membership expired last December," she said. Her insurance stopped reimbursing her for the membership, but she said she knew she wanted to stay active.

Campbell-Carter ultimately chose to start budgeting for weekend classes, and during the week she does yoga, gardening or goes on a "PRAYER walk," which is the term used in the Friendship Baptist health ministry to describe a neighborhood walk a group or individual can participate in. "It's great to feel increases in my muscle strength and tone. Also, I sleep so good at night," she said.

Laboy sees the proof at the gym, not just in herself but in others.

"When I'm at the gym working out and I see some of my diabetes self-management folks walking around on the track or working out on the equipment, my heart just smiles," she said.

But there's so much more to do."I can't just plant the seed and leave," Laboy said. "I have to keep coming back and watering it, and when I come, I'm coming with a tank of water and fertilizer."

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Overcoming diabetes through churches in Columbia's African-American community - Columbia Missourian

DUBLIN--(BUSINESS WIRE)--

Research and Markets has announced the addition of the "Type 1 Diabetes Mellitus Forecast in 12 Major Markets 2017-2027" report to their offering.

Type 1 Diabetes Mellitus (T1DM) is a multisystem disease that progressively destroys the pancreas' ability to produce insulin. This leads to a chronic condition of defective metabolism of fat, carbohydrates and proteins due to the lack of insulin. It occurs mainly in childhood and adolescents, however a rising number of latent autoimmune diabetes of adulthood (LADA) cases have been reported mainly due to a better understanding and diagnosis of the disease.

This report provides the current prevalent population for Type 1 Diabetes Mellitus across 12 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Brazil, Japan, India, China and Russia) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.

Providing a value-added level of insight from the analysis team, several of the main symptoms and co-morbidities of Type 1 Diabetes Mellitus have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.

Reasons to Buy:

- Able to quantify patient populations in global Type 1 Diabetes Mellitus market to target the development of future products, pricing strategies and launch plans.

- Gain further insight into the prevalence of the subdivided types of Type 1 Diabetes Mellitus and identify patient segments with high potential.

- Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries.

- Provide a level of understanding on the impact from specific co-morbid conditions on Type 1 Diabetes Mellitus prevalent population.

- Identify sub-populations within Type 1 Diabetes Mellitus which require treatment.

- Gain an understanding of the specific markets that have the largest number of Type 1 Diabetes Mellitus patients.

Key Topics Covered:

1. Introduction

2. Cause of the Disease

3. Risk Factors & Prevention

4. Diagnosis of the Disease

5. Variation by Geography/Ethnicity

6. Disease Prognosis & Clinical Course

7. Key Comorbid Conditions/Features associated with the disease

8. Methodology for quantification of patient numbers

9. Top-line Prevalence for Type 1 Diabetes Mellitus

10. Features of Type 1 Diabetes Mellitus Patients

10.1 Comorbidities and Sequelae in T1DM Patients

10.2 T1DM patients with Retinopathy

10.3 Prevalence of T1DM defining antibodies

11. Abbreviations used in the report

12. Patient-Based Offering

13. Online Pricing Data and Platforms

14. References

15. Appendix

For more information about this report visit http://www.researchandmarkets.com/research/j3bqpv/type_1_diabetes

View source version on businesswire.com: http://www.businesswire.com/news/home/20170427005670/en/

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Type 1 Diabetes Mellitus Forecast in 12 Major Markets 2017-2027 ... - Yahoo Finance

Smartphones can already control homes and cars, anddiagnosediseases. Chinese and Swiss researchers now show that a smartphone can command engineered cells implanted in diabetic mice to produce insulin.

The researchers demonstrated a clever closed-loop system in which a digital glucometer transmits data on the rodents blood glucose levelsto a smartphone, which processes the data and then signals the implanted cells to deliver insulin.This is a step towards a new era of personalized, digitalized precision medicine, says Haifeng Ye of East China Normal University,who led the work reported in Science.

Cell-based therapies are a radical new medical treatment option being investigated by researchers. The idea is to turn cells into disease-fighting weapons by engineering them to produce therapeutic chemicals and proteins that they would churn out once implanted in the body. Living white blood cells, for instance, have been designed to fight cancer, HIV, and other diseases.Hundreds of cell therapies are undergoing clinical trials. But none can be controlled from outside the body.

Ye and his colleagues have come up with an innovative way to add smarts to cell-based therapy. They chose diabetes as the target disease.

They initially inserted light-sensitive bacterial proteins into mammalian cells. When exposed to far-red light (wavelength of about 730 nanometers), the protein activateda genetic pathway that causedthe cells to produce insulin.

After that success, they team made dime-sizedevices in which circular power-receiving coils surround a hydrogel that is embedded with the engineered cells and far-red LEDs. These devices were implanted under the skin of diabetic mice. When an external transmitting coil wirelessly switches on the LEDs via electromagnetic induction, their light triggers the cells to produce insulin in the animals.

The team made three things to remotely control the engineered cells: a custom-engineered Bluetooth-active glucometer,an Android-based smartphone app,and an intelligent control box that controls the power-transmitting coil.

When the researchers placemice blood samples on the glucometer, it sends measurements to the smartphone via Bluetooth. The phone app compares these levels to a pre-set threshold, then signals the control box to turn on the power-transmitter coil, which switches on the LEDs long enough for the cell implant to deliver the right amount of insulin.

The animals blood glucose typically went down to nondiabetic levels within two hours of irradiation. The system maintained the blood glucose concentration in mice for 15 days without any side effects. After that it could be replaced, Ye says, but a much longer performance or replacement frequency of the implant needs to be further investigated in humans.

One big limitation of the system is that it needs manual blood draws. Another is that the animals need to be close to the transmitting coil and be exposed to EM radiation to switch on the LEDs.

But a bit more engineering could yielda diabetesmonitoring-and-treatment system that isfully automatic and portable. A continuous glucose monitorcould send blood sugar measurements to the users phone. The phone would trigger a battery-powered LED wristband to shine light on the implanted insulin-producing cells.

IEEE Spectrums biomedical engineering blog, featuring the wearable sensors, big data analytics, and implanted devices that enable new ventures in personalized medicine.

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Smartphone-Controlled Cells Keep Diabetes In Check - IEEE ... - IEEE Spectrum

As the diabetes wars have raged, Eli Lilly's (NYSE:LLY) balanced portfolio has helped insulate it from the share price losses dealt to competitor Novo Nordisk (OTCPK:NONOF). But even Lilly can have an off quarter.

Trulicity's growth was more than offset by below-consensus sales for Basaglar and Jardiance - the underperformance of the last of these was surprising given that it has begun marketing on its cardiovascular benefit. When combined with last week's US rejection of rheumatoid arthritis entry Olumiant, these disappointments forced Lilly executives to reassure investors that the company's medium-term guidance of 5% growth could still be met.

Lilly shares fell 3% today following the release of first-quarter results, removing $2.7bn in market valuation. Since the Olumiant complete response letter was announced, shares have fallen 6% (Olumiant setback opens the door to rivals, April 18, 2017).

Bernstein analyst Tim Anderson chalked up some of the losses to profit-taking - before the Olumiant news, shares were up 16% on the year - but acknowledged the effect of Olumiant and diabetes revenue on investor sentiment.

Topline good

In the long view, the Indiana-based group had a positive quarter, with revenue of $5.2bn and earnings per share of $0.98 in line with investor expectations. However, having just got over the news of Olumiant - rejected because of questions over the most efficacious dose and safety characterization - news that diabetes was not necessarily firing on all cylinders was not taken well.

Expectations for Jardiance remain high since it is the first of the SGLT2 class to be allowed to market on the basis of averting cardiovascular death in diabetics, although it could very well be chased by competitors Invokana, from Johnson & Johnson, and Farxiga, from Astrazeneca (NYSE:AZN) (ACC - Jardiance heart benefit looks like a class effect, March 20, 2017).

Lilly diabetes chief Enrique Conterno characterized the SGLT2 class as having flat growth before the cardiovascular data was included on the Jardiance label, but said that since marketing on that claim has begun new patient starts have risen 70% - the miss on Jardiance sales may simply reflect a mismatch between investor expectations and market realities.

Olumiant's bigger setback has investors questioning the 5% revenue growth forecast given that the drug is one of four new products that will post annual sales growth of $1bn or more to counteract losses due to patent expiries. Finance chief Derica Rice offered some comfort: "We've factored in that we won't have 100% success on every molecule" when preparing that forecast, he said.

Olumiant's failure to add US revenue does, however, increase the pressure on the rest of the portfolio to meet sales expectations. And Lilly's exposure to the volatile diabetes space raises the risk that that will not happen.

Editor's Note: This article discusses one or more securities that do not trade on a major U.S. exchange. Please be aware of the risks associated with these stocks.

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Lilly Assures Market As Diabetes Stumbles - Seeking Alpha

The incidence of cardiovascular diseases in Sweden has decreased sharply since the late 1990s. These are the findings of a study from Sahlgrenska Academy which included almost three million adult Swedes. In relative terms, the biggest winners are persons with type 1 and type 2 diabetes.

"This is a huge improvement and a testament to the improvements in diabetes and cardiovascular care throughout Sweden," says Aidin Rawshani, medical doctor and doctoral student in molecular and clinical medicine.

The study, which was published in The New England Journal of Medicine, shows that the incidence of cardiovascular diseases and deaths among individuals with diabetes in Sweden dropped significantly between 1998 and 2014. The population in general exhibited the same trend, albeit to a smaller extent.

Among persons with type 1 diabetes, with an average age of 35 years, the incidence pf cardiovascular disease was reduced by 40 per cent during the period in question. In the control group of persons of similar age but without diabetes, the decrease was 10 per cent.

Among individuals with type 2 diabetes, with an average age of 65 years, the incidence of cardiovascular disease decreased by 50 per cent. Among control persons of similar age without diabetes, the decrease was 30 per cent.

Surprising results

"We were surprised by the results, specially for persons with diabetes. Some smaller studies in the past have indicated that numbers were improving, but nothing of this magnitude," says Aidin Rawshani.

In total, approximately 2.96 million individuals were studied, of which 37,000 had type 1 diabetes and 460,000 had type 2 diabetes. The results of the study are based on linked processing of data from the National Diabetes Register, the Cause of Death Register and the part of the Patient register that concerns inpatient care.

In addition to matching by age and gender, the groups that were compared were also matched geographically using register data from LISA (the longitudinal integration database for health insurance and labour market studies).

The deaths that took place in the groups during the study period were almost exclusively related to cardiovascular disease. Individuals with diabetes have previously shown to suffer a risk of cardiovascular disease and early death that was between two and five times as high as in the general population.

Better risk control

"One of the main findings of the study is that both deaths and the incidence of cardiovascular disease is decreasing in the population, both in matching control groups and among persons with type 1 and type 2 diabetes. One paradoxical finding is that individuals with type 2 diabetes have seen a smaller improvement over time regarding deaths compared to the controls, while persons with type 1 diabetes have made an equal improvement to the controls," notes Aidin Rawshani.

The positive trends that have been observed in the study are most likely due to an increased use of preventative cardiovascular medicines, advances in the revascularisation of atherosclerotic disease and improved use of instruments for continual blood sugar monitoring, and the fact that Swedish diabetes care has generally worked well with good treatment guidelines and quality assurance efforts.

"Out study and analysis does not include explanations of these trends, but we believe that it is a matter of better control of risk factors, better education patients, better integrated treatment systems for individuals with chronic illnesses and individual care for persons with diabetes. There is often an entire team working with a patient, ensuring that their needs are met," says Aidin Rawshani.

Story Source:

Materials provided by University of Gothenburg. Note: Content may be edited for style and length.

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Decrease in cardiovascular diseases benefits persons with diabetes ... - Science Daily

CHICAGO Edwin Velarde is tackling his Type 1 diabetes with what he's calling an "epic" bike challenge that begins in Chicago next month.

Velarde, a former Chicago resident who now lives in Oak Park, Calif., will pedal his bike from the Adler Planetarium to Atlanta a journey of about 800 miles from May 30-June 8. He's raising money for the American Diabetes Association.

"I will do all I can during this ride to promote healthy lifestyles and inspire others to take control of their wellness," said Velarde.

He said he's excited to meet "people along the way and able to talk about diabetes, and how I manage my condition.

"Thats exciting as I hope there are possibilities of inspiring others," he said. "I change one life, it makes it worth the effort through all this."

Edwin Velarde

Velarde was diagnosed with diabetes when he was 29. He said he struggled with high blood glucose until a friend gave him a bike a few years ago. Since then, he's avoided thousands of insulin injections and kept his blood glucose levels stable.

His route will take him through Terre Haute, Ind., Evansville, Ind., Nashville and Chattanooga, Tenn. before arriving in Atlanta. He also posted information about his ride to The Chainlink site hoping for guidance on the safest routes from Chicago.

The Centers for Disease Control and Prevention considers the area the "Diabetes Belt" of America because 11.7 percent of the people within it have diagnosed diabetes, compared to 8.5 percent outside the belt.

Velarde will arrive in Chicago a few days early to train on the Lakefront Trail and near his former home in North Park.

"I am doing this ride to give back by raising awareness about diabetes and modest funds for the American Diabetes Association," he said. "I am hoping to meet other cyclists around the places I pass through. Theres this bond I think among cyclists and would like to expand my circle. Maybe they can spread the word also about what Im trying to do, maybe even ride with me parts of my epic journey."

For more information on Velarde's challenge, click here.

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800-Mile Ride Through 'Diabetes Belt' Takes Cyclist From Chicago To Atlanta - DNAinfo

Diabetes continues to be a growing problem among our nations children. Did you know that every year there are more than 25,000 children diagnosed with diabetes?

To begin with there are two different types of childhood diabetes, type 1 and type 2; and while both cause an elevated blood sugar, they also differ in many ways.

Type 1 diabetes was formerly called juvenile onset diabetes and is typically diagnosed in children and adolescents. Only 5 percent of those with diabetes have type 1. Many parents worry that their child may develop diabetes because they eat too much sugar. While eating sugar is not good for you, it does not directly cause type 1 diabetes.

Type 1 diabetes is an autoimmune disease in which the immune system attacks and destroys the beta cells (insulin producing cells) of the pancreas. Scientists are not exactly sure why this occurs, but it seems to be a combination of genetic and environmental factors, and actually has nothing to do with diet.

Type 1 diabetes comes on suddenly and causes dependence on insulin for the rest of the childs life. The symptoms of type 1 diabetes usually include extreme thirst, frequent urination (day and night), increased appetite and sudden weight loss. Children who develop type 1 diabetes appear tired, thin and sick. To many parents who worry that their child is diabetic, I tell them that they really cannot miss the symptoms and that just drinking a lot of water will not be the only symptom.

Fortunately, the ways in which insulin is given continues to improve and most children now use an insulin pump, which delivers insulin in a more consistent manner than in previous years. But, even with new insulin delivery systems and the hopes for pancreas transplants, type 1diabetes is challenging for a family to manage.

Type 2 diabetes, which was previously called non-insulin dependent diabetes, differs in that it was previously typically diagnosed in adults, but it is now rising in children. In type 2 diabetes, the body isnt able to use insulin in the right way and the glucose in the blood stream is less able to enter the cells. This is called insulin resistance. So, the pancreas tries to produce even more insulin to keep blood sugar levels normal. Over many years the pancreas may wear out completely. Type 2 diabetes is sometimes controlled with an oral medication rather than insulin.

Type 2 diabetes seems to develop more frequently in those children who are overweight, less active and often have a parent with diabetes. As more children in this country have developed obesity, the number of cases of type 2 diabetes has also continued to rise. In many cases, if a child changes their lifestyle, eating a healthy diet, losing weight and exercising, the body may be able to restore normal insulin balance. In this way, type 2 diabetes differs from type 1 diabetes.

If you are concerned that your child is showing any signs of diabetes, make sure to consult your doctor. Continue to promote healthy eating habits and daily exercise.

Sue Hubbard, M.D. /The Kids Doctor; the kidsdr.com

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The Kid's Doctor: Why is childhood diabetes on the rise? - Chicago Sun-Times

(Sen. Yvanna Cancela speaks with Majority Leader Aaron Ford and diabetes patients.Courtesy Yvanna Cancela) The state of Nevada is taking a new approach to tackling the rising price of prescription drugs with a new bill.

The bill, introduced in March by state Senator Yvanna Cancela, has already faced opposition from lobbyists and nonprofit patient groups that disagree with the bill's approach to reining in prescription drug spending.

Nevada is one of 23 states with proposed legislation to take on the rising cost of prescription drugs. But unlike others that focus on drug prices in a general sense, Cancela's bill focuseson two specificgroups of drugs that are used to treat diabetes: insulin and biguanides.

It's the latest milestone in government actions at the local, state, and national levels that attempt to change the way wespend money on prescription drugs.

Diabetes is a group of conditions in which the body can't properly regulate blood sugar that affects roughly 30 million people in the US. And for many people living with diabetes including the1.25 million people in the US who have Type-1 diabetes injecting insulin is part of the daily routine.

insulin prices humalog novolog V2

(The list price of Humalog and Novolog, two short-acting insulins, over 20 years. The list prices don't factor in any rebates or discounts the drugmaker pays out.Andy Kiersz/Business Insider) Insulin, a hormone thathealthy bodies produce, has been used to treat diabetes for almost a century, though it's gone through some modifications. In the past few years, the list price of insulin has increased routinely.

The list price of the most commonly used insulins have increased roughly 300% over the last decade. Technically, there's no "generic" insulin, though a cheaper version of a long-acting insulin did come on the market in 2016. There are cheaper medications forbiguanides, such as metformin, which are used to treat Type-2 diabetes.

Before becoming a state senator, Cancela workedas a director for the Culinary Workers Union in Las Vegas, which represents about 60,000 workers. The union pays for its members health insurance through a self-funded trust, which Cancela told Business Insider gave the organization a lot of access to details about how its health funds were being spent. One of the drugs she noticed was becoming a problem for members was insulin.

There are roughly 281,000 adultsliving in Nevada, or 12% of the total population, that have one of the two types of diabetes, with another 39% in the prediabetes stage, in which blood glucose levels are elevated but not to the point of type-2 diabetes. Because diabetes is one of the biggest medical problems in Nevada, Cancela said, it made for a perfect starting point to introduce legislation.

The Nevada bill, known as SB265, takes four mainapproaches to confronting the drugmakers that make insulin and biguanides to treat diabetes.

Like most legislation that tries to rein in prescription drug spending, SB265 is facing its fair share of pushback and criticism.

Cancela said there's been around 70 lobbyists who have come in for the session to oppose the bill, which is more than double the number present for Nevada's 2015 session,according to The Nevada Independent. There's also been a number of patient groups that have spoken out as well, including those representing people with lupus and epilepsy.

"Proposed legislation in the Nevada State Senate unfairly targets people with diabetes, would be a major windfall for health insurance companies, and leaves patients wondering whos next," Lupus of Nevada said in a Facebook post. "Were specifically worried that Nevadans with Lupus could be singled out."

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(A Type 1 diabetes patient holds up bottles of insulin.Reuters/Lucy Nicholson) Nine pharmaceutical companies submitted lettersin opposition to the bill, as well as pharma's lobbying group PhRMA and biotech's lobbying group BIO. Many brought up their opposition to disclosingmore information about how they set their prices.

A letter from Novo Nordisk a company that manufactures insulin and other diabetes medications argued that the bill doesn't take into account the rebates drug companies pay out to middlemen. That issue was raised in a number of the letters opposing the bill.

"This proposal would impose significant new, complex and punitive requirements on drug manufacturers when manufacturers already provide competitive discounts to payers and represent only a single component of the enormously complex US drug pricing and distribution system," the company said in the letter. "This complexity, which the proposed legislation fails to address, has resulted in confusion around what patients pay for medicines."

To be sure, there's more to the story than just the list price a manufacturer sets. Along the way, there are as many as five companies that have a stake in the price of a medication. But there's a lack of transparency about the portion each player gets. To counter that, some drug companies have started disclosing their net prices, or the amount it actually receives in return for the drug after factoring in any rebates or discounts paid out to middlemen.

Sanofi noted in its opposition letter that its net price for Lantus, a long-acting form of insulin, fell over five years.

Sanofi said in a statement to Business Insider:

"Sanofi believes this legislation will fail to achieve its intended purpose and may actually restrict patients access to important medications. As a company founded on and committed to science and improving health, we understand that affordability and access to our products is critical for patients and society, and we are committed to working with all stakeholders to ensure patients have affordable access to the treatments they need in a system that is sustainable and continues to promote ongoing investments in science and innovation."

Others, like Ken Thorpe, the chairman of the Partnership to Fight Chronic Disease (a group that partners witha number of healthcare companies and patient organizations) and a health policy professor at Emory University, criticizedthe idea that the bill is a way to help those living with diabetes. He argued in a piece in the Nevada Appeal that the price capswon't keep people from getting diabetes.

"If they're really trying to get the cost of healthcare to grow at a slower rate, this is not the way," he told the Appeal. Instead, he said, there should be more of a focus on preventing diabetes.

Cancela said that's something she's working on as well, calling SB265 "one piece of the puzzle." She has another piece of legislation that would promote urban agriculture to increase access to healthy foods in low income communities.

The bill is still with the Health and Human Services committee, meaning it needs to clear the Assembly and Senate before it makes its way to the governor.

But of course, drug price bills have failed in the past. In November 2016, Californians voted against a proposition that would've capped prescription drug prices at what the Department ofVeterans Affairs pays for them.

Cancela understands that it's not going to be an easy ride.

"We're trying to do something that's never been done before," Cancela said.

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One in 7 people in Nevada are living with diabetes, and the state is now pushing a new approach to tackle the cost ... - Yahoo Finance