Category Archives: Diabetes

The Zimbabwe Daily

New potential cause of type 1 diabetes Science Daily T1D, previously known as juvenile diabetes, affects an estimated 1.5 million Americans and is the result of the loss of insulin-producing cells in the pancreas. The prevailing belief was that the root cause of T1D was the immune system mistakenly ... Curing Diabetes Natural Home Remedies Offer Type 2 Diabetes CureMilitary Technologies Is the cure for Diabetes here?The Zimbabwe Daily all 5 news articles »

See the original post:
New potential cause of type 1 diabetes - Science Daily

Science Daily

Collaborative diabetes clinic lowers health care costs Science Daily Diabetes cost the U.S. an estimated $245 billion in 2012, in direct medical costs and reduced productivity. Health care providers are facing increasing pressure to achieve better patient outcomes at a lower cost. To help address these issues ...

See the original post here:
Collaborative diabetes clinic lowers health care costs - Science Daily

Q. A friend of mine just had an LVAD inserted. What's that?

A. LVAD stands for left ventricular assist device. The left ventricle is the pumping chamber of the heart. When it is damaged, its pumping ability is reduced, and the patient may develop heart failure, often manifested by shortness of breath, ankle swelling, cough, fatigue and exercise intolerance. The damaged left ventricle can be helped by medication, but in extreme cases, sometimes the only option is a new heart a heart transplant. But some people (because of age or other medical conditions) may not be transplant candidates. And others are candidates but are so sick that in the past they used to die while waiting for a donor heart to become available. That's where an LVAD can come into play. It is a mechanical pump that is surgically implanted, and it works with the patient's own heart to improve circulation and blood flow. Symptoms often are improved, and LVADs have been a lifesaver for many patients. The devices have become better, more reliable, smaller and safer over the years. And while they certainly have important complications associated with their use, LVADs have enabled very sick patients to live better and longer lives.

Wynne is vice president for health affairs at UND, dean of the School of Medicine and Health Sciences, and a professor of medicine. He is a cardiologist by training.

Submit a question to Health Matters at healthmatters@med.und.edu or Health Matters, 501 North Columbia Road, Stop 9037, Grand Forks, ND 58202-9037. Remember, no personal details, please.

The content of this column is for informational purposes only and does not substitute for professional medical advice or care. The information provided herein should not be used for diagnosing or treating a health problem or disease. If you have or suspect you may have a health problem, you should consult your health care provider. Never disregard professional medical advice or delay in seeking it because of something you have read in this column.

See original here:
New devices help diabetes patients - Grand Forks Herald

Researchers at Columbia University have retracted a 2013 paper in The Journal of Clinical Investigation, after uncovering abnormalities in the stem cell lines that undermined the conclusions in the paper.

Last year, corresponding author Dieter Eglidiscoveredhe could notreproduce key data in the 2013 paper because almost all the cell lines first author Haiqing Hua used contained abnormalities, casting doubt on the overall findings. When Egli reached out to Hua foranswers, Hua could not explain the abnormalities. As a result, Hua and Egli agreed the paper should be retracted.

Since some of the details of how the paper ended up relying on abnormal cells remain unclear, the university confirmed to us that it is investigating the matter.

Heres the retraction notice for iPSC-derived cells model diabetes due to glucokinase deficiency, cited 42 times:

The corresponding authors were made aware of karyotype abnormalities through a routine quality control test of pluripotent stem cells used in the studies reported in this paper. After extensive internal review and genetic analysis, they found that the karyotypes of some of the cells used for the experiments reported were abnormal and that the normal karyotypes shown in Figure 1 and Supplemental Figure 2 were not from cell lines used in the study. They also cannot confirm the endonuclease-mediated correction of the mutant GCK G299R allele. H. Hua takes responsibility for the characterization and presentation of cell line karyotypes and the genetic manipulations. Because of these discrepancies, the authors wish to retract the article. They apologize for these errors and for any inconvenience caused to others.

In the fall of 2009, Hua joined Rudolph Leibels diabetes and nutrition lab at Columbia University, under the co-supervision ofEgli, who brought an expertise in stem cell biology. Hua told us:

The aim of my research project was to leverage the expertise of both Dr. Egli (on stem cell biology) and Dr. Leibel (on diabetes) and to demonstrate the concept that the islet cells generated in the lab from diabetic patients through stem cell technology would present comparable dysfunction as the islet cells in the patients body. Because we chose patients with genetic mutations that cause diabetes, we were hoping to demonstrate that correction of the mutations would restore the normal function of the islet cells.

But, Hua noted, he wasnt and still isnt an expert in stem cell biology, so he had to learn on the job:

When I began the project, I never worked with cells before and had no experience or understanding of cell line karyotype.

Hua started by generating several cell lines from a diabetic patient. To check that the genetic makeup of these cell lines were the same, he sent several for analysis to a contracted service, which examines 20 cells per cell line and generates a report:

I did karyotype analysis for the cell lines right after I derived them, probably in 2011, before I started to do any experiments on them. The reports came back with some cells being normal and some being abnormal. To be fair, I thought what I learned from Dr. Egli was that it is a normal phenomenon that some cells are abnormal as long as the number is not high.

Indeed, Egli, an assistant professor of stem cell biology at Columbia University Medical Center, confirmed that pluripotent stem cells are often prone to undergo abnormalities:

Karyotypic abnormalities are common, and occur in many cells upon extended cultures, so this is not in and of itself a concern. Often one can go back to earlier cultures that are normal.

Hua published the work in 2013, along with a relatedpaper in Diabetes in 2014, -Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome. Hua believes, at a conceptual level, both papers achieved the goal of demonstrating that the correction of the mutations would restore the normal function of the islet cells.

In 2014, Hua told usthat he moved back to China for family reasons.

Last year, other investigators asked Egli to share the cells lines from the 2013 study. To ensure he was providing high quality material, Egli sent what he believed to be normal cell lines from the study for quality control testing. Egli said thats when he learned many of the cell lines contained abnormalities.

To suss out the problem, Egli went back to the cell lines stored in the lab to look for normal cells:

Dr. Hua had already left the University at that time and so I personally started to look for karyotypically normal cells. There were no normal cells to be found.

Egli explained what the abnormalities meant for the study results:

You could best describe the abnormalities of the [cell] lines [Hua] used as mumbo-jumbo. There were multiple rearrangements in the chromosomes in the cell lines and thus you wouldnt know if the effects you saw were due to gene modifications or simply due to those rearrangements. Essentially, the abnormal cell lines question the entire paper, and its very unlikely the paper would have been accepted at the journal.

When Egli failed to reproduce the data from the 2013 paper, he contacted Hua to find out where the normal cell lines were. But Hua was not sure in fact, he told us it was a surprise to learn that most of the cell lines he had used contained abnormalities, adding:

another layer of complication is that when cells became karyotype abnormal, they could behave like cancer cells, namely they could start as minor portion in the culture but later on took over and became majority. So another mistake we made was that we didnt perform karyotype analysis at the end of the study to make sure that after all the experiments we did, the cells were still normal.

A spokesperson at Columbia University verified that the university is conducting an investigation into the issues:

I could confirm that there is an ongoing investigation.

When Hua was informed of these issues, he suggested the study be retracted:

Immediately, I proposed to Dr. Egli and Dr. Leibel that we should retract the publication because we were not certain about the conclusion any more.

Hua takes responsibility for what happened, adding:

So this was done at very early phase of my research, and I was busy with a lot of parallel projects since I was the first post-doc of Dr. EgliBecause I wasnt understanding the problem correctly, I put up the figures with normal karyotype as first figure for the publication and continued my research with one particular cell line.

Egli also talked about the experience of retracting a paper:

Retracting a paper is not a rewarding process, and often reports stay in the literature even if they should not. Retracting the paper exposes us to the possibility of damage. I took proactive steps to investigate and retract because I wanted to correct the record. This would not have happened without my initiative involving 2-3 months of benchwork.

Hua described this as a truly unfortunate and painful chapter, which he hopes others can learn from:

The health of academic world and advance of science really depends on correction of previous mistakes and clearance of uncertainties. [A]voiding overwhelming multitasking is important. At the first year of my research, I was setting the lab together with Dr. Egli and meanwhile performed more than 100 experiments. Each of them would took more than 10 days and I was really stacking all the experiments. This particular project was about one fourth of my effort at that time. My biggest recommendation or reflection would be that it is very very very important to quality control and characterize starting materials of a project. Many people, including myself, are more focused on rushing the project forward and do not realized that if the starting materials are flawed, anything built on them has no solid foundation.

Hat tip: Rolf Degen

Like Retraction Watch? Consider making a tax-deductible contribution to support our growth. You can also follow us on Twitter, like us on Facebook, add us to your RSS reader, sign up on our homepage for an email every time theres a new post, or subscribe to our daily digest. Click here to review our Comments Policy. For a sneak peek at what were working on, click here.

Read the original here:
Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper - Retraction Watch (blog)

A diet that mimics fasting temporarily put mice in a starvation state, reversing diabetes in the animals, according to a new study. The diet was also shown to reduce the risk factors in people with pre-diabetes

Research by investigators at the University of Southern California showed the special, fasting-mimicking diet triggers the development of insulin-producing cells in mice with diabetes. The study was published in the journal Cell.

In humans, an earlier study of the diet reduced the risk factors of diabetes, such as elevated blood sugar, in people who were headed toward development of the disease. An article on the diet in humans appeared in Science Translational Medicine.

In both Type 1 diabetes and in the later stages of Type 2 diabetes, the beta cells of the pancreas are destroyed. But the authors said the diet appears to "reboot" the body, switching on genes that trigger the release of stem cells, master cells responsible for organ development.

More than fasting required

However, fasting alone is not the key to restoring insulin levels. Scientists said refeeding after the brief starvation diet, with specially calibrated nutrients, is critical to kickstarting the production of new beta cells.

FILE - A woman fills a syringe as she prepares to give herself an injection of insulin.

The process of stem cell activation is the same as seen in embryos to stimulate organ growth, according to gerontology professor Valter Longo, the director of USC's Longevity Institute and senior author of both studies. He said the fasting-mimicking diet can be used to reprogram cells without any genetic alterations.

"So basically the system is using some of the same program that we use during embryonic and fetal development to regenerate the pancreas once the food comes back around," he said. "And that's the trick. It's not so much the starvation. It's really the combination of the starvation and the refeeding." And, he stressed, "the refeeding's got to be a high-nourishment one."

Study participants put on the high-fat, low-calorie, low-protein diet consumed between 800 and 1,100 calories daily for five days in a row each month for three months. After each fast, they were refed with nutrient-rich foods.

Researchers found fasting triggered the production of a protein called Ngn3, which generated new, healthy beta cells that secreted insulin. They saw production of insulin in a dish in pancreatic cells extracted from mice and from healthy human donors and patients with both types of diabetes.

Scientists found the diet replaced damaged insulin-producing cells with new functioning ones in mice placed on the diet for four days.

Heart disease, cancer risks

The investigators have also amassed evidence that the fasting-mimicking diet reduces the risk of age-related diseases, including heart disease and cancer. It may also hold benefits for people with multiple sclerosis, said researchers.

FILE - A woman who suffers from diabetes is seen walking on a treadmill as part of an exercise program to help control the disease.

But Longo said people with diabetes should not try the diet at home yet because it can drop blood sugar to perilously low levels if they don't know what they are doing. "We warn people that, particularly [for people with] Type 1 or patients that inject themselves with insulin, it can be very risky or even lethal," Longo cautioned.

He said investigators were poised to begin larger human clinical trials of the fasting-mimicking diet in the next six months.

Continue reading here:
Fasting Diet Reverses Diabetes in Mice - Voice of America

BENGALURU:There is growing burden of diabetes in India. The Indian Council of Medical Research (ICMR) estimated that the country already had around 65.1 million diabetes patients.

As per a survey by National Center for Biotechnology Information in Bangalore, the prevalence of diabetes was 12.33 per cent and of pre-diabetes was 11.57 per cent of the total population.

Increasing age, being overweight and obese, sedentary lifestyle, unhealthy and untimely dietary habits have well proven association with prevalence of diabetesPre-diabetes is a condition that predates diabetes mellitus. In pre-diabetes stage the levels of blood glucose are higher than normal but, remain below diabetic range.

The condition is very common among Asians, especially Indians and data from different sources across the countries showed that nearly 20 per cent of urban Indians are prone to it. Certain lifestyle changes taken in pre-diabetes stage can prevent diabetes.

Symptoms

Diabetic patients with uncontrolled sugars usually suffer from increased frequency of urination, weight loss and extreme fatigue, but in pre-diabetes stage, the patient normally does not have any symptoms. A regular monitoring referred to as screening test would be the only way to diagnose the condition.

Causes and Risk factors

Insulin is an essential element to transport glucose that the body produces to convert into energy. In pre-diabetes, the body is not able to produce enough insulin or is not able to function efficiently, also called insulin resistance leading to a higher-than-normal blood sugar level and possibly pre-diabetes. Prevention and treatment

Pre-diabetes is the warning sign before it progresses to become type 2 diabetes. It is complex, multi-factorial, hugely influenced by genetic predisposition, lifestyle factors and excessive calorie intake. Eating well, eating healthy and regular exercise helps prevent progression of pre-diabetic patients to Type 2 diabetes. It is observed that consumption of vegetables had a significant connection with diabetes.

People who consumed more than two servings of vegetable had lesser prevalence of diabetes. Many studies have shown that use of consuming high water soluble fibers present in vegetable and fruits and polyunsaturated fat in fish, help in preventing diabetes.

Similarly, people at risk of and also those identified with pre-diabetes would benefit from lifestyle a change that includes weight loss and exercise for at least 30 minutes every day. This can improve insulin resistance and can lower elevated blood sugar levels diabetes.

The author is a Consultant Diabetologist & Endocrinologist, Fortis Hospital, Bannerghatta Road

See the rest here:
Before diabetes strikes - The New Indian Express

March 1, 2017 Patients with fatty liver disease may need a more intense dose of exercise. Credit: University of Queensland

Short bursts of high-intensity exercise could help people with non-alcoholic fatty liver disease reduce their risk of type 2 diabetes.

A trial led by University of Queensland School of Human Movement and Nutrition Sciences researcher Dr Shelley Keating will investigate if high intensity interval training (HIIT) can improve insulin sensitivity, fitness and other cardiovascular disease risk factors.

"Other than weight loss, there is no accepted therapy for improving non-alcoholic steatohepatitis (NASH) a type of fatty liver disease which is strongly linked to type 2 diabetes and cardiovascular disease," Dr Keating said.

"We have recently demonstrated that exercise therapy reduces liver fat in adults with obesity, but patients with NASH may need a more intense 'dose' of exercise.

"We hope to establish that high-intensity exercise is a safe, feasible and effective therapy for improving insulin resistance and other cardio-metabolic risk factors.

"Given that up to one-third of Australians have non-alcoholic fatty liver disease, and the subsequent rate of progression to NASH is around 30 per cent, the impact on the community is significant."

Study participants will complete 12 weeks of HIIT supervised by an accredited exercise physiologist at UQ's St Lucia campus in Brisbane, followed by 12 weeks of HIIT at home.

"The sessions will involve short, intense bursts of exercise around four minutes on a treadmill or exercise bike at near maximum capacity - interspersed with more moderate exercise," Dr Keating said.

"Health measures including insulin sensitivity, body composition, vascular function, and fitness will be assessed before and after the supervised and home-based phases.

"It is very important that individuals can continue on with HIIT in the long-term so that the health benefits can be sustained," Dr Keating said.

People with biopsy-proven NASH, or their clinicians, should contact Dr Keating (see below) for details on how to take part in the trial.

Explore further: Diet and exercise can improve kidney function in patients with fatty liver disease

Non-alcoholic steatohepatitis (NASH) is a potentially serious liver condition characterized by excess fat in the liver associated with inflammation and scarring. NASH may progress to cirrhosis of the liver and liver cancer, ...

(Medical Xpress)High-intensity interval training (HIIT) is touted as the fastest way to get lean, but according to ground-breaking new research from the University of Sydney's Charles Perkins Centre, only endurance exercise ...

A University of Queensland researcher is trialling a 12-minute exercise plan that aims to fight type 2 diabetes in a flash.

Listening to music may make it easier for people to adopt short duration exercise regimens that could help them stay in shape, according to researchers at UBC's Okanagan campus.

Understanding how exercise affects language learning could help patients with brain conditions such as stroke, Alzheimer's and Parkinson's disease.

Time-poor people who do fewer repetitions during high-intensity interval training (HIIT) workouts may get better fitness benefits than those who complete more, according to a University of Stirling analysis.

Short bursts of high-intensity exercise could help people with non-alcoholic fatty liver disease reduce their risk of type 2 diabetes.

A diet designed to imitate the effects of fasting appears to reverse diabetes by reprogramming cells, a new USC-led study shows.

(Medical Xpress)A team of researchers with members from several institutions in Germany and one in the U.K. has discovered what might be a way to tell if a newborn child is likely to develop type 1 diabetes as they grow ...

People with diabetes are at high risk of developing heart disease. Despite knowing this, scientists have struggled to trace the specific biology behind that risk or find ways to intervene. Now, UNC School of Medicine researchers ...

A long-term study by Monash University researchers - the first of its kind - has found that gastric band surgery has significant benefits for moderately overweight people with type 2 diabetes. Previous studies have focused ...

Blood sugar triggers the secretion of insulin from cells in the pancreas, a process that is impaired in diabetes. A team of Yale researchers have identified a mechanism at the membranes of these pancreatic cells that controls ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Original post:
Can fast and furious exercise prevent diabetes? - Medical Xpress

DUBLIN--(BUSINESS WIRE)--

Research and Markets has announced the addition of the "China Diabetes Market Report: Patients, Prevalence, Oral Antidiabetics, Insulin and Diagnostics" report to their offering.

China currently has the highest number of diabetics in the world. The disease has presently reached epidemic proportions in the adult population. Around three decades ago, less than one percent of the Chinese adult population had diabetes. These levels, however, have increased to around 12 percent - making it the diabetes capital of the world.

The rise of diabetes in China can be attributed to a number of factors. Driven by a strong economic growth over the past few decades, the Chinese population has become richer, fatter and less mobile. Apart from urbanisation and sedentary lifestyles, Chinese people are also genetically more vulnerable to diabetes compared to Europeans and many other population groups. Other factors such as poor awareness of health issues, high consumption of white rice, poor healthcare infrastructure, etc. have also driven the prevalence of the disease.

China's diabetes statistics may ring alarm bells for the government and healthcare authorities, for drug and diagnostic manufacturers, however, it represents a goldmine. Fuelled by a continuous increase in healthcare expenditures, the market for diabetes drugs and diagnostics is expanding robustly in the country. This is creating lucrative opportunities for global healthcare companies at a time when growth rates in the more developed markets have declined.

The report provides both current and future trends in the prevalence, demographical breakup, diagnosis and treatment of diabetes in China. The research study serves as an exceptional tool to understand the epidemiology, market trends, therapeutic structure, competitive structure and the outlook of the Chinese diabetes market. This report can serve as an excellent guide for investors, researchers, consultants, marketing strategists and all those who are planning to foray into the China diabetes market in any form.

Key Topics Covered:

1 Preface

2 Research Methodology

3 Executive Summary

4 Introduction

5 Diabetes Disease Overview

6 China Diabetes Epidemiology

7 China Diabetes Market

For more information about this report visit http://www.researchandmarkets.com/research/9h3kbw/china_diabetes

View source version on businesswire.com: http://www.businesswire.com/news/home/20170228006026/en/

Read the original post:
China Diabetes Market Report 2017: Patients, Prevalence, Oral Antidiabetics, Insulin and Diagnostics - Research and ... - Yahoo Finance

When the Kansas Senate comes back after this weeks midsession break, it may consider legislation to form a comprehensive state plan to fight diabetes.

House Bill 2219 would instruct the Kansas Department of Health and Environment to conduct an analysis of state costs from diabetes, identify best practices to prevent and control the condition, and develop a budget to implement those practices.

It also would require the agency to report on the plans progress every two years.

Just before the break the House voted 117-7 to pass the bill, which is one of the main legislative priorities for the American Diabetes Association. Four other states passed similar plans in 2016, according to the organization.

According to the American Diabetes Association, diabetes affects almost 13 percent of the adult population in Kansas and leads to about $2 billion in health care costs annually.

The associations numbers include an estimated 69,000 Kansans who have undiagnosed diabetes. Numbers from the federal Centers for Disease Control and Prevention that include only those with diagnosed diabetes ranked Kansas at 21st highest in the country, at 9.5 percent.

People with diabetes are unable to produce or properly use insulin, a hormone that turns food into energy. There are two main forms:Type 1 diabetes, previously known as juvenile diabetes, andType 2 diabetes, the most common kind. Common complications of diabetes include heart and blood vessel disease, kidney damage, blindness and nerve damage.

Larry Smith is president of the National Diabetes Volunteer Leadership Council, a Kentucky-based nonprofit that testified for the Kansas bill. He said Kentucky was the first state to enact a diabetes action plan and about one-third of states have them now.

It has opened the eyes of the Legislature and the government that there is a problem and its a big drain on their budget, said Smith, whose daughter has Type 1 diabetes.

Smith said the push to fight diabetes in Kentucky began with Gov. Ernie Fletcher, a Republican physician who led the state from 2003 to 2007.

He realized the cost that diabetes put on the state budget was substantial and held them back on a number of things they wanted to do in terms of education or infrastructure and so forth, Smith said.

A similar bill died in the Kansas House in 2015. But Rep. Susan Concannon, a Republican from Beloit who brought this years bill, said the current version was voted through in part due to testimony from Rep. Blaine Finch, a Republican from Ottawa, and from his teenage daughter who has diabetes.

It was a little more meaningful for us this year to have one of our colleagues make it more personal, Concannon said.

Andy Marso is a reporter for KCURs Kansas News Service, a collaboration of KCUR, Kansas Public Radio and KMUW covering health, education and politics in Kansas. You can reach him on Twitter@andymarso. Kansas News Service stories and photos may be republished at no cost with proper attribution and a link back to kcur.org.

Read the original here:
Anti-Diabetes Plan Progressing In Kansas Legislature - KCUR

Ever since he was diagnosed with Type 1 diabetes as a fifth-grader at Claremont Elementary School, Alex Simmons has been committed to raising funds for the Juvenile Diabetes Research Foundation (JDRF).

Now a Washington-Lee High School sophomore, he moves closer to his goal of raising $100,000 for diabetes research during a Feb. 25 event that drew more than 130 neighbors and friends to the Lyon Park Community Center.

The party, which included a silent auction, was hosted by five Arlington families who have supported Simmons since his diagnosis. The event raised more than $15,000, with all proceeds going directly to the JDRF, and boosted Alex Simmonss fund-raising totals so far to $75,500 in donations.

Ever since our son Alex was diagnosed with diabetes five years ago, the JDRF has been a big part of our lives, said Anita Simmons, a new member of the board of directors of the Juvenile Diabetes Research Foundation Greater Chesapeake and Potomac Chapter. They provide hope and guidance for so many families as we learn to cope with this diagnosis and protect our childrens health.

At the celebration, guests enjoyed a fully catered dinner by the Hard Times Caf, beverages from Dogfish Alehouse, a silent auction and the musical sounds of the Roger Taylor Quartet as they connected over a common cause.

Many Arlington businesses made donations, including local artist Sabrina Cabada, independent bookstore One More Page and SPARK Business Academy.

Previous fund-raisers have included local basketball tournaments, small parties with a purpose and a bingo night hosted by Simmons grandmother, Alease Brooks, a resident of Arlingtons The Carlin.

Bill Parsons, executive director of the Greater Chesapeake and Potomac Chapter, said the Feb. 25 event was one of the largest peer-to-peer fund-raising events his organization has seen in this area.

The commitment this family has made to bringing awareness to juvenile-diabetes issues and raising money for research has been incredible, he added. We all love the Simmons family Anita Simmons is a force of nature.

Complications of juvenile diabetes can be disabling and life-threatening. Each day, Alex Simmons who over the winter played on the varsity boys basketball team at Washington-Lee must monitor his blood sugar levels and give himself six to eight insulin shots, yet he remains focused on the positive.

I am not on this journey alone, and my close friends, family and relatives make this process much easier for me, he said. I encourage everyone who can to please donate money to the Juvenile Diabetes Research Foundation, not only for me, but for all of the children throughout the country who dont have it as easy as I do.

Alex Simmons is now a youth ambassador for the organization, and also leads a team that takes part in the annual OneWalk event on the National Mall.

Anita Simmons said their family is especially grateful to Rich Kelly and Cindy MacIntyre of the Hard Times Caf for providing all of the food for the fund-raising event, as well as for the help they extended to Alex and his family when he was first diagnosed with the disease. The Kellys daughter also has Type 1 diabetes, and they are strong supporters of Juvenile Diabetes Research Foundation.

For information on Alex Simmons fund-raising efforts, see the Web site at http://bit.ly/2mmGi5g.

Read more:
Washington-Lee student working to raise $100000 for diabetes research - Inside NoVA