Page 100«..1020..99100101102..110..»

Category Archives: Gene therapy

The Science of the Next 150 Years

Posted: January 13, 2013 at 8:02 am

What scientific and technological milestones can we envision 50, 100 and 150 years hence?

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article


Source:
http://rss.sciam.com/click.phdo?i=bb22bbe61dfa476fb230c7787f0d7954

Posted in Gene therapy | Comments Off on The Science of the Next 150 Years

Gene Therapies Will Cure Many a Disease (preview)

Posted: January 6, 2013 at 7:04 pm

The Science Of The Next 150 Years: 50 Years in the Future [More]



Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article



Source:
http://rss.sciam.com/click.phdo?i=72f945621480bfc5969f6a7a29254aaf

Posted in Gene therapy | Comments Off on Gene Therapies Will Cure Many a Disease (preview)

Mucopolysacccharidoses: from understanding to treatment, a century of discoveries

Posted: December 23, 2012 at 8:00 am

After the first description of a patient recognized as a MPS case was made in 1917, several similar cases were described and identified. Observations reported in the middle of the twentieth century concerning the presence of acid mucopolysaccharides (later called glycosaminoglycans, or GAGs) in tissues and especially in urine of patients were instrumental in providing an identity for these diseases, which became referred as "mucopolysaccharidoses" (MPS). In the late 1960's it was demonstrated that MPS were caused by defects in the breakdown of GAGs, and the specific enzyme deficiencies for the 11 types and subtypes of MPS were identified thereafter. Genes involved in the MPS were subsequently identified, and a large number of disease-causing mutations were identified in each one. Although ...

MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Source:
http://www.medworm.com/index.php?rid=6870800&cid=c_449_50_f&fid=37480&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS1415-47572012000600006%26lng%3Den%26nrm%3Diso%26tlng%3Den

Posted in Gene therapy | Comments Off on Mucopolysacccharidoses: from understanding to treatment, a century of discoveries

Mucopolysacccharidoses: from understanding to treatment, a century of discoveries

Posted: December 22, 2012 at 5:47 am

After the first description of a patient recognized as a MPS case was made in 1917, several similar cases were described and identified. Observations reported in the middle of the twentieth century concerning the presence of acid mucopolysaccharides (later called glycosaminoglycans, or GAGs) in tissues and especially in urine of patients were instrumental in providing an identity for these diseases, which became referred as "mucopolysaccharidoses" (MPS). In the late 1960's it was demonstrated that MPS were caused by defects in the breakdown of GAGs, and the specific enzyme deficiencies for the 11 types and subtypes of MPS were identified thereafter. Genes involved in the MPS were subsequently identified, and a large number of disease-causing mutations were identified in each one. Although ...

MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Source:
http://www.medworm.com/index.php?rid=6870800&cid=c_449_50_f&fid=37480&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS1415-47572012000600006%26lng%3Den%26nrm%3Diso%26tlng%3Den

Posted in Gene therapy | Comments Off on Mucopolysacccharidoses: from understanding to treatment, a century of discoveries

Global Transfection (Gene Delivery, DNA Delivery, Protein Delivery, SiRNA Delivery) Technologies (Lipofection, Calcium …

Posted: December 19, 2012 at 3:41 pm

NEW YORK, Dec. 19, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

http://www.reportlinker.com/p01057834/Global-Transfection-Gene-Delivery-DNA-Delivery-Protein-Delivery-SiRNA-Delivery-Technologies-Lipofection-Calcium-Phosphate-Electroporation-Nucleofection-Magnetofection-Gene-Gun-Viral-Market-2012--2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Genetically_Modified_Organism,_GMO

Transfection is an enabler technology used for many cell based research activities with applications spanning production of recombinant proteins and recombinant cell lines, gene therapy, delivery of therapeutics and also drug discovery. This research report provides a brief description on transfection technologies, its evolution, comparative analysis, market landscape analysis, competitive scenario and emerging technology and application trends. Global research and development Network, Innovation and Spin offs have been discussed. The report tracks regional adoption and development trends, providing strategic recommendation to stay active and compete in the market space. An impact analysis of major drivers and restraints influencing the growth of the market is mapped for five year period.

Cell research is a major driving factor for transfection market, as more than 60% of the users are of academic institutions and researchers. Research in gene transfer is being performed in in vivo conditions for different therapeutic applications; there is a growing demand for new transfection technologies to address unmet needs for therapeutic delivery which is driving the transfection market.

Key Restraint:

Home brewReagents restricts sale of commercial kits

Home brew reagents are still the preferred choice of reagents for transfection by researchers all over the world. Most of the researchers prepare their own reagents from their laboratory to conduct their research. This is true for most of the reagent based transfection reactions. This allows them to reduce cost involved in purchasing commercial kits.

Transfection is an enabler technology which is used in many cell research activities, however only few cell lines are majorly used in these experiments restricting the scope of the study. Transfection in hard to transfect cells is the need of hour and it is a major challenge. There are few upcoming transfection technologies like nucleofection and magnetofection which are an off-shoot of electroporation, which have the potential to address these challenges but are currently cost prohibitive due to which the technologies may have a much slower uptake in the developing world.

The report also discusses new opportunities for investment in the upcoming areas like Gene therapy, Stem cell research and Electro-chemotherapy.

Different transfection technologies are analyzed through a multi-criteria based decision making process which provides competitive benchmarking. Further, the report analyses technology management strategies and technology road mapping for the forecast period. Profiles of over 20 Key companies in the area of Transfection technology sector have been provided. Key players include Life Technologies, Sigma Aldrich, Lonza, Promega, Qiagen, Bio-Rad, Roche, Polyplus Transfection, Mirius Bio, Maxcyte, etc.

More here:
Global Transfection (Gene Delivery, DNA Delivery, Protein Delivery, SiRNA Delivery) Technologies (Lipofection, Calcium ...

Posted in Gene therapy | Comments Off on Global Transfection (Gene Delivery, DNA Delivery, Protein Delivery, SiRNA Delivery) Technologies (Lipofection, Calcium …

The Science of the Next 150 Years

Posted: December 19, 2012 at 12:32 pm

What scientific and technological milestones can we envision 50, 100 and 150 years hence?

[More]



Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article



Source:
http://rss.sciam.com/click.phdo?i=bb22bbe61dfa476fb230c7787f0d7954

Posted in Gene therapy | Comments Off on The Science of the Next 150 Years

World Changing Ideas 2012 (preview)

Posted: December 2, 2012 at 7:59 am

Scientists and engineers dream about big advances that could change the world, and then they try to create them. On the following pages, Scientific American reveals 10 innovations that could be game changers: an artificial alternative to DNA, oil that cleans water, pacemakers powered by our blood, and more. These are not pie-in-the-sky notions but practical breakthroughs that have been proved or prototyped and are poised to scale up greatly. Each has the potential to make what may now seem impossible possible. -- The Editors

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article


Source:
http://rss.sciam.com/click.phdo?i=b2ba3706ed26d9143fea77a07b425555

Posted in Gene therapy | Comments Off on World Changing Ideas 2012 (preview)

World Changing Ideas 2012 (preview)

Posted: December 2, 2012 at 7:58 am

Scientists and engineers dream about big advances that could change the world, and then they try to create them. On the following pages, Scientific American reveals 10 innovations that could be game changers: an artificial alternative to DNA, oil that cleans water, pacemakers powered by our blood, and more. These are not pie-in-the-sky notions but practical breakthroughs that have been proved or prototyped and are poised to scale up greatly. Each has the potential to make what may now seem impossible possible. -- The Editors

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article


Source:
http://rss.sciam.com/click.phdo?i=b2ba3706ed26d9143fea77a07b425555

Posted in Gene therapy | Comments Off on World Changing Ideas 2012 (preview)

Cultivator of Brain Parts

Posted: November 18, 2012 at 8:00 am

Yoshiki Sasai is not just an ordinary tissue engineer who tries to coax stem cells to grow into fully formed bodily structures. It is true that Sasai has made his mark by taking on big projects like using stem cells to whip up a retina, cortical tissue and the cerebellum, involved with balance and movement. But his research has gone deeper by delving into the way stem cells organize themselves into complex structures under the influence of genes and the prenatal environment. Read a profile of Sasai here to accompany “ Grow Your Own Eye ,” Sasai’s own account of growing a retina in the November Scientific American .

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article


Source:
http://rss.sciam.com/click.phdo?i=7291cadd43ac0cf30e9687431d559702

Posted in Gene therapy | Comments Off on Cultivator of Brain Parts

How to Grow a Retina from Stem Cells (preview)

Posted: November 18, 2012 at 8:00 am

In the womb, a ball of identical cells gives rise to varied cell types that ultimately form highly ordered structures and then the full panoply of organs in the human body. The process advances according to an internal biological script that directs each fold and crease of tissue to assume exactly the proper shape and dimension.

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article


Source:
http://rss.sciam.com/click.phdo?i=1e6abdd024c3b29c15070219c99ad16a

Posted in Gene therapy | Comments Off on How to Grow a Retina from Stem Cells (preview)

Page 100«..1020..99100101102..110..»