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Category Archives: Genetic medicine

Medication adherence improves, When Patients Share Their Stories

Posted: March 13, 2011 at 4:03 pm

Dr. Pauline Chen in the NY Times reports that “When Patients Share Their Stories, Health May Improve”. HC Catalyst uses the same methodology to increase patient adherence to prescription medicines.

hcCatalyst Adherence Driver uses patients to motivate other patients to stay adherent. And, we do this without remunerating, scripting or training. It’s genuine and without the liability issues associated with paid or trained spokespersons.

Details on http://www.hccatalyst.com/solutions.html

 

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Clinical Research Sites Struggle With Increasing Trial Complexity yet most depend on, Google (or other search sites) as the primary information tool

Posted: March 13, 2011 at 4:02 pm

A new survey of 500+ clinical research site professionals outlines the  impact of complex, clinical trials in clinical trial sites. The survey focused on 3-year trial trends and found key challenges in subject recruitment/retention and tracking and reporting data. Increased complexity also impacted trial financials– especially negotiating contracts and managing profitability.

The December, 2010 survey was conducted among investigators, study coordinators and other clinical site professionals from large organizations, such as Mayo Clinic and Johns Hopkins, hospitals like Rush Presbyterian and the Hospital for Sick Children, as well as multi-specialty and private practices. Clinical Research Site Training (CRST), conducted the survey.

Analysis of the survey findings shows that

  • 66% of large organizations report an increase in trials conducted
  • 60% of trial sites report increasing difficulty in managing trial profitability
  • 40% report increasing difficulty in recruiting and retaining subjects
  • Training remains a major issue, even though over 50% report an increase in training
  • 80%+ of nurses want more QA training
  • 60%+ of all respondents want more FDA Audits training

The survey also explored sites’ Web use for work information. In spite of increased specialized Web content about the clinical research site “world”, awareness and usage were both relatively low.

  • Google (or other search sites) was the primary information tool
  • Only the NIH and Clinical Trial Network sites have over 50% awareness among all site professionals
  • Usage of major specialized sites averaged less than 40% for nurses and less than 20% for doctors

CRST suggest that clinical research sites should:

  • Increase training on financial management, site QA, subject recruitment/retention and FDA inspections;
  • Manage the convergence of increased and more complex trials by improving both new staff recruitment and experienced staff retention;
  • Reach out on the Web for new/improved ways of working from both formal information sites and clinical research site communities.”

Full results of the survey are available on the CRST website http://www.crstnet.com

Contacts

CRST
Lester Levine, 484-798-7503
President
Fax: 215-477-2522
lester.levine@crstnet.com

 

 

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Questions for the CRO

Posted: March 13, 2011 at 4:02 pm

Posted in Genetic medicine | Comments Off on Questions for the CRO

Medication adherence improves, When Patients Share Their Stories

Posted: March 13, 2011 at 4:02 pm

Dr. Pauline Chen in the NY Times reports that “When Patients Share Their Stories, Health May Improve”. HC Catalyst uses the same methodology to increase patient adherence to prescription medicines.

hcCatalyst Adherence Driver uses patients to motivate other patients to stay adherent. And, we do this without remunerating, scripting or training. It’s genuine and without the liability issues associated with paid or trained spokespersons.

Details on http://www.hccatalyst.com/solutions.html

 

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AstraZeneca Announce Real-World Evidence Data Collaboration

Posted: February 14, 2011 at 2:19 pm

AstraZeneca Pharmaceuticals LP (NYSE: AZN) and HealthCore, Inc., the health outcomes research subsidiary of WellPoint, Inc. (NYSE: WLP), announced a collaborative agreement to conduct real-world studies designed to determine how to most effectively and economically treat disease

Unlike controlled clinical trials, real-world evidence studies use observational data such as electronic medical records, claims information and patient surveys. By examining data associated with the delivery of care, real-world analyses can assess treatment impact on hospital length of stay, readmissions, overall health status, cost of care and other key evidence-based outcomes.

A leader in health outcomes research, HealthCore maintains the largest data environment in the nation. HealthCore’s near real-time, fully-integrated data environment combines medical, pharmacy, laboratory results and other information drawn from 36 million enrollees in local Blue Cross and/or Blue Shield plans with concentrated populations in 16 states.

 

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How to improve R&D productivity: the pharmaceutical industry’s grand challenge

Posted: February 14, 2011 at 2:19 pm

 

 

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AstraZeneca Announce Real-World Evidence Data Collaboration

Posted: February 14, 2011 at 2:16 pm

AstraZeneca Pharmaceuticals LP (NYSE: AZN) and HealthCore, Inc., the health outcomes research subsidiary of WellPoint, Inc. (NYSE: WLP), announced a collaborative agreement to conduct real-world studies designed to determine how to most effectively and economically treat disease

Unlike controlled clinical trials, real-world evidence studies use observational data such as electronic medical records, claims information and patient surveys. By examining data associated with the delivery of care, real-world analyses can assess treatment impact on hospital length of stay, readmissions, overall health status, cost of care and other key evidence-based outcomes.

A leader in health outcomes research, HealthCore maintains the largest data environment in the nation. HealthCore’s near real-time, fully-integrated data environment combines medical, pharmacy, laboratory results and other information drawn from 36 million enrollees in local Blue Cross and/or Blue Shield plans with concentrated populations in 16 states.

 

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How to improve R&D productivity: the pharmaceutical industry’s grand challenge

Posted: February 14, 2011 at 2:16 pm

 

 

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IBM Files Application to Patent The Patent

Posted: January 4, 2011 at 7:38 am

Ever heard of people getting obnoxious amount of money to conduct research or get a PhD for pointless research. Thats what came to my mind when I first came across this news from IBM.

Just remind these were some of the winning ideas that funded by Government in US for Research papers and PhDs

1. the National Science Foundation once gave $100K grant to research why American players go to greater lengths to mod the popular MMO than do Chinese WoW players.

2.  Pressures Produced When Penguins Pooh — Calculations on Avian Defaecation”, Polar Biology, 2004

3. Suicide rates are linked to the amount of country music played on the radio, , Medicine, 2005

4. Rats can’t always tell the difference between Japanese spoken backwards and Dutch spoken backwards, winner, Linguistics, 2007

 As much as I stand to loose a chance to get a job at IBM by this post, its  so hard not to think loud, and ask IBM what the heck was wrong with your brains, when you made the decision to patent the patent.

 The Original Post Pasted from http://www.tomshardware.com/news/ibm-patents-the-patent,11868.html

IBM Files Application to Patent The Patent Process

6:40 PM – January 3, 2011 by Douglas Perry – source: ConceivablyTech

   Reading through IT patents these days requires patience and tolerance. When you can patent common sense, there is clearly something wrong with the system. But as long as no changes are being made, you are inviting people to exploit what is available and IBM has just demonstrated what may be possible, if one of their most recent patent applications is accepted by the USPTO.

The company felt it would be beneficial to patent the patent strategy process all the way from training inventors, to competitor monitoring and protecting (i.e. suing someone) a patent from infringement. This patent does not describe anything new, but a strategy that is being pursued by anyone who owns a patent and especially patent trolls or people like Paul Allen, who is just taking another shot at suing Google for patent infringement.

The patent application could mean that IBM in fact is working on a software that automates patent management or the company simply felt it was necessary to patent the idea of filing a patent and treating it in the way it could be considered common sense. It is especially revealing how much focus the inventor put on a “defend” module that implies a lawsuit strategy. It would take a genius to figure that out.   

Reading through this patent is a good lecture how a patent these days should not look like. IBM is the natural place for this idea as there is no other company that files for as many patents (and receives as many patents) as IBM does. But if the patent idea gets approved

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Adverse Events in Hospitals- United States Department of Health Report slams current measures in US hospitals

Posted: December 21, 2010 at 9:34 am

OFFICE OF , INSPECTOR GENERAL of US Department of Health and Human Services, released a report on the national incidence of adverse events for hospitalized Medicare beneficiaries, the preventability of such events, and associated costs to Medicare.

The report released last month month found that one in seven of the patients experienced an adverse event such as excessive bleeding, a hospital-acquired infection or aspiration pneumonia. Those events, both preventable and not preventable, led to about 180,000 deaths a year.

The complete report available at

http://oig.hhs.gov/oei/reports/oei-06-09-00090.pdf


 

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