Category Archives: Hawaii Stem Cells

Stem cell treatments of various kinds are now widely available in America at more than 100 stem cell clinics offering non-FDA approved interventions for dozens of conditions.

American patients are often recruited on the Internet to travel around the US or to Mexico and other countries.

How much do these stem cell treatments cost?

American clinics charge approximately $10,000 per treatment. Notably, many patients gets more than one of these non-FDA approved treatments and must pay each time of course.

Some clinics have reduced prices to the $7,000-$8,000 range. Interestingly, costs for treatments outside of the US are usuallyfar higher than in the US,charging anywhere from $20,000 all the way up to $100,000. These clinics still generally have Americans as clientele. Whether inside or outside the US, insurance does not cover the costs of these potentially dangerous, unproven treatments.

Clinic profits are difficult to estimate and vary depending on the type of stem cells and other factors such as malpractice insurance cost. However, I have heard estimates of the clinics own costs being around $1,000-$2,000 per treatment, yielding a very high profit margin.

Part of the way that clinics cut corners to boost their profitsis by not following FDA regulations, putting patients in danger. Clinics typically do not do pre-clinical studies to get evidence of safety and efficacy before starting to sell their offerings to patients. Clinics also do not include sufficient follow up in the cost of the treatments. They do not publish their data to get peer review and feedback. They often do not have GMP compliant facilities or devices.

Patients themselves are frequently unable to afford these expensive, unproven stem cell treatments, and so they turn to their communities including churches, friends, and family to do fundraisers. For example, a coach reportedlyrecently raised $70,000 for a stem cell intervention fromhis community. Update: The non-FDA approved Stemedica stem cell intervention sold in Tijuana via partner Novastem reportedly costs $32,000-$40,000 a pop.

With the rapidly increasing number of clinics right here in the US, in theory one might imagine costs would go down due to competition. Its not clear if that is driving some clinics to lower prices.

Of course othercosts to patients going to dubious clinics, sometimes not considered, include the price of false hope, potential injury due to dangerous stem cell treatments, possibly being excluded from a real clinical trial in the future, and injury from deferring other arguably more real treatments.

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How Much Do Stem Cell Treatments Really Cost? | Knoepfler ...

THURSDAY, July 30, 2015 (HealthDay News) -- A new method for delivering stem cells to damaged heart muscle has shown early promise in treating severe heart failure, researchers report.

In a preliminary study, they found the tactic was safe and feasible for the 48 heart failure patients they treated. And after a year, the patients showed a modest improvement in the heart's pumping ability, on average.

It's not clear yet whether those improvements could be meaningful, said lead researcher Dr. Amit Patel, director of cardiovascular regenerative medicine at the University of Utah.

He said larger clinical trials are underway to see whether the approach could be an option for advanced heart failure.

Other experts stressed the bigger picture: Researchers have long studied stem cells as a potential therapy for heart failure -- with limited success so far.

"There's been a lot of promise, but not much of a clinical benefit yet," said Dr. Lee Goldberg, who specializes in treating heart failure at the University of Pennsylvania.

Researchers are still sorting through complicated questions, including how to best get stem cells to damaged heart muscle, said Goldberg, who was not involved in the new study.

What's "novel" in this research, he said, is the technique Patel's team used to deliver stem cells to the heart. They took stem cells from patients' bone marrow and infused them into the heart through a large vein called the coronary sinus.

Patel agreed that the technique is the advance.

"Most other techniques have infused stem cells through the arteries," Patel explained. One obstacle, he said, is that people with heart failure generally have hardened, narrowed coronary arteries, and the infused stem cells "don't always go to where they should."

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New Stem Cell Tactic Shows Promise for Heart Failure

Global Stem Cells Group has announced plans to participate in the 15th International Congress of Aesthetic Medicine in Boca Del Rio, Veracruz July 9-12, 2015. Charles Mahl, M.D. and David B. Audley will represent GSCG as keynote speakers

MIAMI (PRWEB) June 16, 2015

Charles Mahl, M.D. and David B. Audley will represent Global Stem Cells Group, Inc. as keynote speakers at the 15th International Congress of Aesthetic Surgery in Boca del Rio in Veracruz, Mexico July 9-12, 2015. Mahl, a member of the Global Stem Cells Group Scientific Advisory Board, and Audley, the chairman and general secretary of the Regentech Alliance (RTA), will join more than 1,500 aesthetic surgeons and specialists in the fields of anti-aging and regenerative medicine from around the globe for the four day event.

Hosted by the Instituto de Estudios Superiores en Medicina (Institute of Advanced Studies in Medicine) in Veracruz, conference attendees will include an international lineup of physicians and medical practitioners in a variety of disciplines who will gather to discuss the newest therapies, protocols and innovative procedures available in aesthetic medicine.

Mahl, who maintains an active practice in regenerative medicine, preventive aging and pain therapies, will bring his expertise in prolotherapy, platelet rich plasma injections and stem cell therapies to the conference. Audley is a pioneer in the field of regenerative medicine and the founding executive director of the International Cellular Medicine Society (ICMS), the first professional medical association dedicated to the development of standards and accreditation for medical facilities engaged in cell-based therapies.

The conference will feature workshops in botulinum toxin applications for beginners and advanced students, and peeling treatments for stretch marks. Some of the topics to be addressed at the event include updates in aesthetic surgery, regenerative medicine therapies, platelet rich plasma applications, clinical and therapeutic stem cell applications, facial fillings, COFEPRIS guidelines, legal issues associated with aesthetic surgery and more.

The conference will take place at the Hotel Galerias Plaza Veracruz, Blvd. Adolfo Ruiz Cortines #3495, Costa Verde, Boca Del Ro, Veracruz. For more information on the 15th International Congress of Aesthetic Surgery, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com or call 305-224-1858.

About Global Stem Cell Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.

About Charles Mahl, M.D.:

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CALGARY, AB / ACCESSWIRE / June 10, 2015 / Avagenesis Corp. (Avagenesis or the Company) (TSX VENTURE: VVA), is pleased to announce the completion of a third party performance validation study of its automated bioprocessing and stem cell isolation system (Avagenesis System). The results confirm that the Avagenesis System significantly outperforms competing systems in all metrics: high stem cell recovery, excellent reproducibility and rapid processing time. The study was conducted by a team of leading stem cell experts at the Industrial Technology Research Institute (ITRI), the national research organization of Taiwan and a world leader in research, technology and high tech product development.

In the study conducted by ITRI (ITRI Study), the Avagenesis System was evaluated and validated using seven fresh human lipoaspirate samples. Viable nucleated cell recovery and stem cell recovery performances were measured using an ADAM-MC Automated Cell Counter (NanoEnTek Inc.) and colony forming assays and then compared to a study entitled Adipose Stromal Vascular Fraction Isolation: a Head-to-Head Comparison of Four Commercial Cell Separation Systems by Aronowitz JA, Ellenhorn JD, December 2013, Plastic Reconstructive Surgery. 2013;132:932e939e (Aronowitz Study). The Aronowitz Study reviewed the following systems: Celution 800/CRS System (Cytori Therapeutics Inc., USA NASDAQ:CYTX), Multi Station (PNC International, South Korea), Cha-Station (CHA Biotech Inc., South Korea KOSDAQ: 085660.KQ), and Lipokit with MaxStem (Medi-Khan International Inc., South Korea).

Cell recovery yields are key performance metrics representing the ability of a system to extract cells from adipose tissue without damaging the cells. The ITRI Study found that the Avagenesis System yielded a mean of 801,000 167,000 viable nucleated cells (8.01 1.67 x 105) from each gram of human lipoaspirate tissue (mean SD, n=7, median: 786,000 viable nucleated cells/g (7.86 x 105)), with a range of 570,000 1,060,000 viable nucleated cells/g (5.70 x 105 1.06 x 106), representing 2X, 7.5X, and over 20X more viable nucleated cells recovered than the comparable numbers reported for Celution, Multi Station, and Lipokit respectively, in the Aronowitz Study. The viability of cells recovered by the Avagenesis System is 84.8% 3.8% (mean SD, n=7), similar to Celutions 84.7% viability reported in a study entitled The Celution System: Automated Processing of Adipose-Derived Regenerative Cells in a Functionally Closed System (Fraser et al., Adv Wound Care (New Rochelle) 2014 Jan;3(1):38-45)(Fraser Study).

The ITRI Study also found that 7.2% 2.4% of the viable nucleated cells in the output of the Avagenesis System are mesenchymal stem cells (MSCs) as characterized by colony-forming unit-fibroblasts (CFU-F), compared to the reported 0.6% 1.7% achieved by Celution (Aronowitz and Fraser Study), 0.35% achieved by Multi Station and 0.20% achieved by Lipokit. Because of the significantly higher viable cell recovery and stem cell colony counts, the Avagenesis System extracted approximately 14X, 76X, and 640X more mesenchymal stem cells than Celution, Multi Station, and Lipokit did, respectively, from each gram of human lipoaspirate processed. Specifically, the Avagenesis System extracted on average 57,700 MSCs/g of human lipoaspirate processed, whereas Celution, Multi Station, and Lipokit only extracted approximately 1920 3950 MSCs/g (Aronowitz and Fraser Study), 750 MSCs/g and 90 MSCs/g, respectively. A 50 ml sample of lipoaspirate generated on average 2,600,000 MSCs (2.6 x 106) using the Avagenesis System. To obtain the same number of MSCs, approximately 0.7 1.5 liters, 3.8 liters and 32 liters of human lipoaspirate would be needed using Celution, Multi Station, and Lipokit, respectively. Volumes of this size are not attainable clinically due to the limited processing capacities of the systems in the Aronowitz Study and the inherent limitations of liposuction once patient-specific considerations and overall safety are taken into account.

Three Avagenesis Systems were also tested side-by-side by ITRI using four fresh human donor lipoaspirate samples to evaluate machine-to-machine variability, a critical metric bearing on performance reproducibility. The resulting measure of machine-to-machine variability was 2.4%, suggesting that the systems can perform stem cell extraction with exceptional consistency and reproducibility.

The mean processing time in the Aronowitz Study ranged from 88 to 115 minutes. The Avagenesis System had a mean processing time of 65 minutes making it the fastest automated adipose processing system ever developed and manufactured for autologous point of care applications.

With the Avagenesis System, there is now an instrument available to all researchers and clinics that is proven to consistently provide premium stem cells of the highest quality. This cost effective breakthrough in standardization and reproducibility provides the highest quantity and quality of stem cells recovered at the point of care, accelerating the revolution in stem cell research, autologous stem cell therapies and cosmetic surgery, said Dr. Richard Cook, Chief Medical Officer of Avagenesis.

About the Industrial Technology Research Institute

Founded in 1973, Industrial Technology Research Institute is a Taiwan non-profit R&D organization engaging in applied technology research and technical services, aiming to innovate a better future for society. Since its inception, ITRI has incubated more than 260 startups and spinoffs, including well-known global semiconductor leaders such as Taiwan Semiconductor Mfg. Co. Ltd. or TMSC (TWSE: 2330; NYSE: TSM) and United Microelectronics Corp. or UMC (TWSE: 2303; NYSE: UMC). ITRI is one of only seven entities recognized globally as a United States FDA Premarket Notification 510(k)s Third Party Review Accredited Persons under FDA Modernization Act 1997.

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Global Stem Cells Group and Marina Medical, Inc. announce plans to conduct joint stem cell training courses worldwide. GSCG subsidiary Adimarket will distribute stem cell products to Latin America in conjunction with the joint training program.

MIAMI (PRWEB) June 04, 2015

MIAMI, June 4, 2015Global Stem Cells Group and Marina Medical, Inc. have announced plans to conduct joint stem cell training courses for physicians and qualified medical professionals worldwide. Sunrise, Florida-based Marina Medical is an established leader in design, manufacture and distribution of medical devices for OBGYN, plastic and aesthetic surgery, regenerative medicine and urogynecology.

Marina Medicals recently launched Koume Cannalus division manufactures instruments for regenerative medicine procedures. Teaming with GSCG for the stem cell training courses will help to further stem cell education among those medical professionals who use Marina Medical instruments.

Global Stem Cells Group subsidiary Adimarket will provide regenerative medicine equipment and supplies for the joint training session held in Latin America.

The Adipose and Bone Marrow Stem Cell Training Course was developed for physicians and high-level practitioners to learn the process of isolating and re-integrating adipose- and bone marrow-derived stem cells through an intensive, hands-on training session. The objective is to arm participating physicians with clinical protocols and state-of-the-art techniques so that they can bring regenerative medicine therapies to their patients in-office.

Global Stem Cells Groups Stem Cell Training, Inc. courses have been extended to approximately 35 countries, allowing a global community of physicians to learn how to apply these new stem cell technologies. For more information, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com, or call 305-224-1858.

About Global Stem Cells Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.

With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine. Global Stem Cells Groups corporate mission is to make the promise of stem cell medicine a reality for patients around the world. Each of GSCGs six operating companies focus on a separate research-based mission; the result is a global network of state-of-the-art stem cell treatments and facilities.

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Global Stem Cells Group and Marina Medical Announce ...

Skin Regeneration Medical Facials Heather Sullivan, RN, Specializes in Dermapen Treatments that Provide a More Natural, Holistic Facial Rejuvenation Procedure

The award-winning Dermapen is the worlds most advanced skin micro-needling device. The new and innovative design of the Dermapen has proven to answer the needs for the successful treatment of wrinkles, fine lines, acne scarring, stretch marks, wound healing stimulation, skin tightening, lifting, and rejuvenation. The Dermapen enhances results through a more controlled and safer method of treatment than other micro-needling devices, all while causing less epidermal damage.

The Bliss Lift by Heather Sullivan includes Dermapen treatments enhanced by a unique topical skin serum of hyaluronic acid and platelet rich plasma (PRP), available in Maui only at Maui Regenerative Medicine. The micro-needling movement of the Dermapen gently pushes this skin serum into your dermal layer to assist in the skin rejuvenation process. Specially created for each client at Maui Regenerative Medicine, the hyaluronic acid is a viscous hydrator naturally made in our bodies that lubricates cells and plumps them up, and adding the individuals PRP introduces ones own growth factors to assist the body in an efficient and effective healing process. At Maui Regenerative Medicine we have been using PRP for collagen regeneration since 2008.

The Dermapen gently punctures into the dermal layer of the skin with a unique spring-loaded disposable needle tip that uses an automated, vibrating stamp-like motion. This causes an injury to the skin resulting in an inflammatory healing response that has a superior effect on collagen turnover and elastin rejuvenation.

The Dermapen offers exceptional results, is easy to use, and has better precision and control than leading alternatives, all at a fraction of the cost. Dermapen is safer and more effective in piercing the skin than traditional skin micro needling rollers due to its unique vertical micro needling technology. The automated needling motion minimizes pain and discomfort, while increasing the effectiveness of treatments by promoting an even absorption of topicals into the skin (such as platelet rich plasma, hyaluronic acid, and peptides).

Dermapen is as effective as Fractional Laser Therapy and IPL, but has a significantly shorter recovery period and does not expose the skin to excess heat and light. The Dermapens needle depth can be adjusted during the course of the procedure to accommodate different treatment areas. Unlike laser treatments, it can easily maneuver around facial contours and treat delicate features like the eyes, nose, and mouth.

Dermapen Micro Needling 3D Animation Video

Heather Sullivan has been a licensed nurse for over fifteen years and has a passion for dermatology, skin health, and wellness. For ten years, she worked extensively in critical care, servicing high adventure areas as a traveling nurse. This led her to the island of Maui, where she serviced the community through work at Maui Memorial Hospital and outpatient care at Kaiser Permanente. Her work in dermatology exposed her to many different mediums, which led her to exploring alternative cosmetic and preventative skincare treatments. She joined Maui Regenerative Medicine in 2012, implementing skin aesthetic and natural rejuvenation procedures and assisting with stem cell injection procedures. Heather holds a Bachelors of Science in Nursing.

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Maui Regenerative Medicine

Global Stem Cells Group and its subsidiary Stem Cell Training announce the companys first European symposium on cellular and regenerative medicine, to be held in Barcelona, Spain Oct. 9-10, 2015. The symposium will be hosted at the Official Medical College Of Barcelona by J. Victor Garcia Gimenez, M.D., of Therapeutic Confrontations.

Miami, FL (PRWEB) May 26, 2015

Global Stem Cells Group and Stem Cell training, Inc. have announced plans for the companys first cellular and regenerative medicine symposium in Barcelona Spain Oct. 9, 2015, followed by a full day, hands-on stem cell training class Oct. 10. The event will be hosted by J. Victor Garcia Gimenez, M.D., President of Therapeutic Confrontations (CONFTERA) in Barcelona.

In response to the medical communitys increasing interest in regenerative medicine and recent advances in cellular therapies, Global Stem Cells Group, CONFTERA, and their faculties have put together a program designed to include cellular communication pathways, influence of the niche in stem cell behavior, and recent studies and supporting investigational protocols for clinical applications. Theory portions of the symposium will be dictated by relevant members of both faculties.

The symposium will be followed by a full day, hands-on training session on Oct. 10 to provide participating physicians with state-of-the-art techniques for isolating and re-integrating adipose- and bone marrow-derived stem cells, along with clinical protocols.

The symposium will be held in the auditorium of the Official Medical College Of Barcelona.

For more information, visit the Global Stem Cells Group website or the Stem Cell Training, Inc. website, email bnovas(at)stemcellsgroup(dot)com, or call 305-224-1858,

About Global Stem Cells Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.

With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.

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Stem Cell Training, Inc. Announces First European ...

Important Questions:

The Catholic Church is concerned with the protection of all innocent human life. Scientific research is important, but it can never come at the expense of the weakest among us.

What Are Stem Cells?:

Stem cells are a special type of cell that can easily divide to create new cells; pluripotent stem cells, which are the subject of most research, can create new cells of various types. Over the last several years, scientists have been optimistic about the possibility of using stem cells to treat a wide range of diseases and other health problems, because stem cells could potentially regenerate damaged tissues and organs.

Types of Stem-Cell Research:

While news reports and political debates often use the term stem-cell research to discuss all scientific research involving stem cells, the truth is that there are a number of different types of stem cells that are being studied. For example, adult stem cells are often drawn from bone marrow, while umbilical-cord stem cells are taken from the blood that remains in the umbilical cord after birth. Most recently, stem cells have been found in the amniotic fluid that surrounds a baby in the womb.

Support for Non-Embryonic Stem-Cell Research:

There is no controversy about research involving all of these types of stem cells. In fact, the Catholic Church has publicly supported adult and umbilical-cord stem-cell research, and Church leaders were among the first to applaud the discovery of amniotic stem cells and to call for further research.

Opposition to Embryonic Stem-Cell Research:

The Church has consistently opposed research on embryonic stem cells, however. For several years now, many scientists have called for greater research on embryonic stem cells, because they believe that embryonic stem cells exhibit greater pluripotency (the ability to divide into different types of cells) than, say, adult stem cells.

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A Catholic View on Stem-Cell Research - Catholicism and ...

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Types of Stem Cells Stem cells can be categorized into five types based on their ability to differentiate or their potency. The stem cell types are as follows: Totipotent Stem Cells These stem cells have the ability to differentiate into any type of cell in the body. Totipotent stem cells develop during sexual reproduction when male and female gametes fuse during fertilization to form a zygote. The zygote is totipotent because its cells can become any type of cell and they have limitless replicative abilities. As the zygote continues to divide and mature, its cells develop into more specialized cells called pluripotent stem cells. Pluripotent Stem Cells These stem cells have the ability to differentiate into several different types of cells. Specialization in pluripotent stem cells is minimal and therefore they can develop into almost any type of cell. Embryonic stem cells and fetal stem cells are two types of pluripotent cells.

- Induced pluripotent stem cells (iPS cells) are genetically altered adult stem cells that are induced or prompted in a laboratory to take on the characteristics of embryonic stem cells. Although iPS cells behave like and express some of the same genes that are expressed normally in embryonic stem cells, they are not exact duplicates of embryonic stem cells.

- Mesenchymal stem cells are multipotent cells of bone marrow that have the ability to differentiate into several types of specialized cells related to, but not including blood cells. These stem cells give rise to cells that form specialized connective tissues, as well as cells that support the formation of blood.

Sources:

Photo Credit: Image: Nissim Benvenisty (PLoS Biol 3(7): e234. doi:10.1371/journal.pbio.0030234)

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