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Category Archives: Hormone Replacement Therapy
Global Hormone Replacement Therapy Market Technology Prospectus to 2027 Pfizer, BioSante Pharmaceuticals and Amgen, Noven Pharmaceuticals, Bayer AG …
Posted: July 21, 2021 at 2:44 am
Global Hormone Replacement Therapy Market Technology Prospectus to 2027 Pfizer, BioSante Pharmaceuticals and Amgen, Noven Pharmaceuticals, Bayer AG The latest report published by Zion Market Research provides the present and future growth prospects for the globalHormone Replacement Therapy Marketby a thorough understanding of the factors that are shaping the trends that are further driving the growth of the market in terms of region & segment, untapped market places, and revenue potential with the consumption pattern and demand of the product. Every section of the report is scoped with an in-depth analysis of the market and represented in a systematic data analysis framework for the forecast period of 2020-2026 for a better understanding of the market. The report on the global Hormone Replacement Therapy Market also incorporates the impact of the Covid-19 pandemic including the factors that have affected the market growth that will allow the investor to invest wisely as per the current trends to stay ahead in the market.
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The global Hormone Replacement Therapy Market is anticipated to reach the market size of xx million USD in 2026 from xx million USD in 2020 by registering a CAGR value of xx %.
The global data in the report on the global Hormone Replacement Therapy Market is categorized by key players [Pfizer, BioSante Pharmaceuticals and Amgen, Noven Pharmaceuticals, Bayer AG, Merck & co., and QuatRx Pharmaceuticals.], segments and its sub-segments and regionsEurope, Asia Pacific, Latin America, North America, and the Middle East & Africa. It also encompasses the future trends, market share, growth rate, and market status for the forecast period of 2020-2026. Porters Five, SWOT Analysis, and supply chain analysis are the analytical tools used to represent the market data in the report. Accurate calculations and estimations are provided in the report in terms of volume and value for the segment and regional growth.
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The report focuses on a detailed analysis of major market players that are functioning in the market to study the market sales, value, and share. Top revenue-generating key manufacturers are involved in the report. Further, a systemic evaluation of drivers, restraints, and opportunities are framed in the report that will allow the user to make effective business strategies to streamline the business and hold the topmost position in the market.
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The chapter of regional analysis in the report highlights the key factors contributing to the market growth. This involves business expansions, presence of major players in the region, favorable government policies & initiatives taken by the regional government for the market growth, and many more. It also involves the challenges faced due to import-export rules and other supply & distribution chain regulations.
To provide an all-inclusive picture of the global Hormone Replacement Therapy Market, the research analyst has obtained insights with the use of primary as well as secondary research. Primary research conducted for the research study includes interviews with industry experts through online & telephone surveys. Whereas, secondary research is conducted to get insights through company annual reports, publications, journals, articles, podcast, and webinars. All the data generated through secondary research is backed by extensive primary research.
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Tips to Manage when You’re in Menopause with ADHD – PsychCentral.com
Posted: July 21, 2021 at 2:44 am
Living with ADHD while going through menopause can be challenging, but there are ways to manage both.
What do ADHD and menopause have in common other than mood changes and inattention?
Though some symptoms are observable on the outside, folks around you may not understand even half of what youre handling internally, let alone that youre managing both at the same time.
Living with attention deficit hyperactivity disorder (ADHD) comes with its own challenges. And if youre going through perimenopause or menopause, you may face more difficulties.
ADHD is a neurocognitive disorder that has three presentations:
People can receive a diagnosis early in childhood as well as late in life.
Dr. Ellen Littman, a clinical psychologist in New York state, explains that estrogen has powerful effects on brain chemistry throughout your lifetime.
Menopause is among the top biggest events to change estrogen in your body, among starting your period and becoming pregnant.
Estrogen is considered neuroprotective, in that high levels increase the availability of neurotransmitters (brain messengers) like dopamine and serotonin, which enhance cognition, mood, sleep, verbal memory, and even ADHD symptoms, Littman says, who is publishing an upcoming review article about the female hormonal effects on ADHD.
However, your levels of estrogen decline beginning in perimenopause and are spent during menopause.
While people face some symptoms off and on during menopause, Littman says those who also have ADHD experience intensified symptoms.
By understanding the relationship between menopause and increased ADHD symptoms, they are less likely to be ambushed by the amplified difficulties they experience, she says.
Both ADHD and menopause are known for patternless shifts in brain activity and hormone changes.
So, you might begin to see how overlapping symptoms happening concurrently or one after the other can worsen the experience of both conditions and make them difficult to manage.
A 2016 study even looks at the effectiveness of using ADHD medication to treat people experiencing executive function issues during menopause.
While going through menopause when you have ADHD can feel overwhelming, there are ways you can manage both conditions.
Finding a psychiatrist whos well versed and experienced in treating ADHD in people going through menopause can help you get the care you deserve.
While it might not be easy to find a psychiatrist with experience in this area, start by asking your current mental health professional or gynecologist for recommendations.
If you cant find a psychiatrist whos familiar with research demonstrating hormone involvement in ADHD symptoms, Littman suggests sharing information or articles (like this one) with them.
If you feel that your credibility is being questioned, its important to feel entitled to finding the clinician who best fits your needs, she says.
Littman suggests finding a gynecologist whos experienced in treating people going through menopause, and who will also work with the doctor who treats your ADHD.
Since women now spend about a third of their lives in menopause, it is critical to find a treatment regimen tailored to your specific needs, she says.
According to a 2019 survey of postgraduate resident trainees in family medicine, internal medicine, and obstetrics and gynecology in U.S. residency programs, only 6.8% of them reported feeling just adequately prepared to manage women experiencing menopause.
No one clinician is knowledgeable about all aspects of each individual experience, but Littman says finding doctors who will collaborate and communicate with your gynecologist can help tailor treatment.
For instance, if your ADHD medications need adjusting, as well as your decreasing estrogen levels, having both your gynecologist and doctor who treats your ADHD collaborate could help.
While pharmacologists often adjust the dosage to meet the new challenges, increased estrogen could address both menopausal and ADHD symptoms. Bioidentical hormone replacement therapy (HRT) is one route to increased estrogen for many women, Littman says.
Although your doctors may be hesitant to communicate with each other, being assertive and informing them of your conditions, as well as bringing information from each doctor to your appointments, can help ensure theyre in tune with whats going on with your body.
While theres a wide range of menopausal symptoms that occur on a continuum, Littman points out that ADHD can worsen symptoms like impaired cognition and mood.
In fact, a 2019 research paper suggests that ADHD symptoms, and even concurrent symptoms from other conditions, are also vulnerable to the hormonal changes experienced during menopause, says Littman.
Both conditions can muddle with your executive functions, a clinical term for your:
If you find that these areas of your life are becoming more difficult to manage, coming up with a plan to help navigate them can make your days easier.
For instance, if keeping and organizing appointments and commitments is difficult, setting an email calendar reminder so you get notifications on your phone, tablet, and desktop can help you stay on track.
If self-monitoring is a blind spot as of late, you could try leaning on your inner circle to gently give you a signal if agitation or strong emotions are coming off more than intended.
You might also look into present moment awareness to reconnect with mindfulness and strengthen your self-awareness.
In addition to seeing a professional, Littman suggests pursuing your own psychoeducation. Consider bookmarking the following resources:
The more you can understand about the relationship between your [brains response to ADHD] and your body in menopause, the more you can be an active participant in your treatment. And the more your support network understands about your challenges, the more supportive and compassionate they can be, Littman says.
While managing your ADHD while going through menopause can be challenging at times, there are ways to make the process easier.
Littman says that on the clinical front, new research brings hope for better treatments ahead.
Were on the brink of an exciting new understanding of the experience of women with ADHD, she says. As new studies continue to implicate the powerful role of hormones in womens experience of ADHD, the potential for more comprehensive and successful treatments may be on the horizon.
You can stay tuned for Littman and teams upcoming study on ADHD and estrogen, titled: ADHD in Females Across the Lifespan and the Role of Estrogen. It publishes August 2021 in The ADHD Report.
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No Shame In Wanting To Look Younger – It Is Natural And You Might As Well Live Longer – Forbes
Posted: July 21, 2021 at 2:44 am
The desire to look younger is natural
Like many other living organisms, humans are born, survive, compete for resources, reach maturity, reproduce, take care of their young, sometimes the young of their young, continuously decline, and die. Evolution needs us for just two purposes adapt and reproduce. But, unlike other species, humans are very conscious of their fate. Humans are very much aware that after reaching peak performance they will eventually grow old and die. We arevery conscious of our fate after reaching peak performance loss off function, frailty, and eventual loss of everything we worked so hard to earn.
We observe our parents, and other elderly around them, attend funerals, and understand that eventually we will get into this state. We are also very contempt with that fate as evolution made sure that. The more ambitious of us are trying to advance science, the rest seek refuge in religion, some in philosophy, some in accumulation of wealth, and some see the continuation of ourselves in our children. But despite the many technological advances transpiring in the laboratories all over the world, there is nothing we can do at this point to escape aging. There are diets, exercises, sleep, and supplements, but these provide very marginal benefits. We do not see 120+ old yoga and diet practitioners or marathon runners around. But these simple habits do help look younger longer. And many people that have very harmful habits like smoking but still diet and exercise to look younger.
Nature is also very unfair and sexist. The females lose reproductive capacity much faster then males. Most females enter menopause between 40 and 60. The average age of menopause in the US is 51. And it is very common to see the couples where the males are significantly older. And for this reason nature found its way to signal the reproductively active people that the older person is not someone they would like to copulate with. And there are many signals: graying hair, wrinkles, body composition, etc. There are few beauty contests for people over 25, and most fashion models become popular in their teenage years. Males can reproduce longer and often remain more attractive to younger females but the level of attractiveness is usually lower and often augmented by social and economic status. It also does seem like the younger women prefer older men more often then the other way around.
So looking younger is a natural desire just like it is natural to seek a younger spouse after a certain age. It is a desire to maintain reproductive viability.
And even though there are not that many aging processes that we can have any control of, the desire to look younger spurred a giant industry. Now it is technologically possible to shave a decade or even two off the way we look via cosmetic interventions, makeup, and surgery.
But whenever we see media images of older celebrities, particularly those who seem much younger than their actual age, the inevitable questions concerning whether "he/she had work done"" or snide remarks about too much botox/liposuction" are rarely far behind.
But why is there such a stigma about wanting to look younger?Despite all these often vicious remarks about cosmetic surgery and other attempts at looking young and attractive, it's not just celebrities who are doing this.While cosmetic surgery used to be reserved solely for the very rich, it is becoming much more affordable, and, not surprisingly, more people than ever are taking advantage.According to the 2019 Plastic Surgery Statistics report released by the American Society of Plastic Surgeons, more than eleven million surgical and nearly fourteen million non-surgical procedures took place worldwide last year, almost four million of those procedures in the United States alone.
Healthcare and medicine
While most cosmetic surgery patients are women,male patients are also becoming more common, and the demand for such services has steadily risen over the past decade.The primary market for women is routine procedures such as breast augmentation, rhinoplasty (nose reshaping), "tummy tucks," and dermabrasion.On the other hand,male patients are getting hair transplantation, breast reductions (or augmentation), calf and pectoral implants,penile extensions (where available), and various other improvements to make them look more masculine as well as attractive.Older clients are also getting procedures specifically intended to make them look younger and thinner, including facelifts, eyelid surgery, botox, and liposuction, to name a few highly demanded anti-aging procedures.
Cosmetic surgery has become such a growth industry that even a cursory Google search can direct would-be users to local clinics.Suppose the desired service is not available locally or cheaply. In that case, would-be customers can look into "medical tourism" involving other countries where they can get surgery and enjoy other travel perks, often in the form of all-expense-paid travel packages. Such medical tourism junkets have become a significant economic boost to otherwise economically disadvantaged countries, and the demand will undoubtedly rise as baby boomers grow older.
In many ways, though,this demand for cosmetic surgery is just the tip of the iceberg.While not everyone can afford (or are interested in) cosmetic surgery,the desire to look younger and healthier has sparked a vast anti-aging industry worldwide.Along with an astonishing number of books, videos, and courses available online offering advice on fighting the signs of age, more people than ever are seeking out various services offering the promise of looking younger and more desirable.That includes weight loss clinics, nutrition counselors, personal trainers, yoga instructors, and a host of other purveyors of youth and beauty.Many older adults seeking out these services seem to be driven by their fears about aging, not to mention unrealistic media representations about the human body (particularly the female body).
But other fears seem to be driving this need to look younger.Though laws banning age discrimination continue to pass in countries worldwide, many older adults feel compelled to hide visible signs of aging to avoid being thought of as "old." The need to look younger has sparked an entire movement surrounding the concept of "agelessness," particularly for women who are far more likely than men to be judged for their appearance.Not surprisingly, many celebrities, male and female alike, have lent their name to various anti-aging products of doubtful validity, all of which promise users the same "agelessness" they enjoy themselves (actress Suzanne Somers and her endorsement of bioidentical hormone replacement therapy, for example).
However, almost inevitably, we are now facing a backlash in the form of a "body positive" movement encouraging men, especially women, to reject what feminist researchers describe as the objectifying of physical appearance favoring a more "genuine" look.It also highlights the double standard that exists between older men and women. While older men can be considered competent regardless of their gray hair and wrinkles, recent research suggests that many women find themselves required to look younger to be accepted.Even those women who refrain from dying their hair to appear more authentic often use other beauty practices to look more youthful. Ironically, for women who choose to make themselves look younger, the most likely backlash they experience usually comes from other women rather than men, a finding recently supported by evolutionary psychology research.
But is there anything wrong with wanting to look younger and more desirable?Numerous studies show the link between perceived attractiveness, self-esteem, and subjective wellbeing.According to one study recently published in the Journal of Women and Aging, the same body dissatisfaction often seen in adolescent girls can also occur in many women as they grow older.An online survey of over three hundred women between the ages of forty-five and sixty-five found that women who were dissatisfied with their appearance and were afraid of growing older were especially prone to depression.They were also far more likely to resort to anti-aging regimens to make themselves look younger.
In another study published last year, researchers found a strong link between perceived self-attractiveness and life satisfaction in women from different age groups (825, 3045, and over 60).The study showed similar results for both overall perceived attractiveness and attractiveness of specific body parts.And people who look younger also feel younger, something that has enormous health benefits, particularly in helping people handle stress (including financial stress), cope with depression and loneliness, and greater sexual satisfaction.
Our recent work on psychological and subjective aging clocks developed using AI also provided a clue that looking younger and thinking more positively about the future correlated with lower mortality. So by looking younger you may actually live longer.
Despite the ongoing political battle over body positivity and "authenticity," wanting to look younger is very natural and certainly no cause for being stigmatized.Ultimately though, simply looking younger is not enough.we still need to invest more efforts into aging and longevity biotechnology.Helping people to live longer and more productive lives remains one of the most significant medical challenges imaginable.Also, eliminating the risk of deadly age-related conditions such as Alzheimer's disease makes research into aging an investment that will repay itself many times over.
Cosmetic procedures coupled with aging clocks may help improve the outlook on life, provide more ... [+] optimistic view on the future, extend reproductive age, and decrease mortality.
To learn more about the exciting and complex field of anti-aging research, consider attending the largest conference on aging research and drug discovery organized every year by the University of Copenhagen and Columbia University 8th Aging Research and Drug Discovery.
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No Shame In Wanting To Look Younger - It Is Natural And You Might As Well Live Longer - Forbes
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Linda Robson says struggle with menopause turned her into a monster – Metro
Posted: July 21, 2021 at 2:44 am
Linda Robson said the menopause turned her into a madwoman (Picture: ITV)
Linda Robson spoke honestly about her experiences with the menopause admitting it made her unbearable to live with.
The actress, 63, said on Thursdays Loose Women that she ended up with a low libido and began to shout at her children.
The menopause is when a woman stops having periods and is no longer able to get pregnant naturally. Symptoms can include hot flushes, vaginal dryness, difficulty sleeping or low mood.
According to the NHS, the severity of the symptoms people going through menopause will experience will vary, and symptoms often begin months or years before the menstruation stops altogether. This is known as perimenopause.
Lindas life was transformed for the better when she was on hormone replacement therapy (HRT) to help relieve the symptoms, but stopped when her sister was battling cancer, which led to her feeling even worse.
She told panelists Charlene White, Brenda Edwards and Nadia Sawalha: I knew I was going through the menopause because my sister went through it at 38 and I started getting all the symptoms, hot sweats, and no one can understand what a hot sweat is until youve had one.
You think its like a flash but its not. It actually goes through your whole body. It goes up through your back, over your head, all your make-ups gone.
She went on: Ive always had quite a high libido and all of a sudden I had no libido and I turned into a mad woman. I was shouting at the kids all the time, at my husband and everything.
So I decided to try the HRT and it just changed my life. But then my sister got breast cancer so me and my other sister came off of HRT. Its the worst Ive ever been.
Nadia interjected: I think that was the beginning of you going downhill.
Linda agreed: I was always quite happy, breezy, and all of a sudden I was a monster. The kids were going to me, Mum youve gotta go back on HRT and as soon as I went back on it my life changed again. My libidos through the roof!
Typically menopause comes on between the ages of 45 and 55, with the average age being 51.
Nadia urged people to speak to someone if any of their discussion resonated with them.
Loose Women airs weekdays from 12.30pm on ITV.
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If youve got a celebrity story, video or pictures get in touch with the Metro.co.uk entertainment team by emailing us celebtips@metro.co.uk, calling 020 3615 2145 or by visiting our Submit Stuff page wed love to hear from you.
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Beasley Allen’s Navan Ward Installed as the American Association of Justice 75th President – Montgomery Independent
Posted: July 21, 2021 at 2:44 am
Navan plans to focus on enhancing diversity and inclusion within the AAJ.
ATLANTA (July 14, 2021) Beasley Allens Navan Ward was installed as the 75th president of the American Association for Justice today during the groups annual meeting. He is the second minority to hold the position, with the first being more than two decades ago. It is this area of representation that Ward and other AAJ leaders are working to improve on in the future and is central to Wards goals for his administration.
I am thankful for my experience at Beasley Allen, where our leadership fosters a culture of inclusion and values the unique backgrounds, experiences and personal achievements of minority lawyers, Ward said. The firm has been recognized for its focus on diversity among its lawyers, including by Law360 as one of the 10 Best Law Firms for Black Attorneys in the U.S and previously recognized as the #1 law firm with African American partners. It is an approach we want to nurture in firms nationwide, Ward said.
The AAJ leadership understands that leaders from diverse backgrounds can strengthen and empower each other and those they lead. Navan has worked with AAJ leadership to recruit, train, and encourage members from different backgrounds (including race, gender, age, geography, and level of career) to become active leaders.
On many different levels and across various landscapes, our country is rebuilding, so it is the perfect time to do the same within the American Association for Justice. The AAJ is an organization that advocates for access to justice and works to preserve the rights given by the 7th Amendment of the U.S. Constitution. It is important that the organization genuinely reflects the diversity that makes it great. I look forward to implementing strategies that will build on the work of the past presidents and strengthen our leadership moving forward, Ward said.
Ward launched what has become the cornerstone of these efforts in 2012 called the American Association for Justice Diversity and Inclusion Leadership Academy. The Leadership Academy trains highly qualified and talented AAJ members, particularly those underrepresented within the association, to help them become more effective leaders. Graduates are encouraged to participate in leadership opportunities throughout AAJ, including the six-to-seven-year national officer track. The Leadership Academy provides leadership and benefits from continued training and leadership development. It is one way the organization guarantees the retention of minority leaders who can ensure underrepresented member groups have a voice in the future of the AAJ.
Ward is the firms lead attorney on the metal-on-metal hip implant litigation and proton pump inhibitor (PPI) litigation and practices from the Atlanta office. Currently, he serves on the Plaintiffs Steering Committee (PSC) for the DePuy ASR Hip Implant Recall Multi-District Litigation (MDL), DePuy Pinnacle Hip Implant MDL and was appointed as co-lead counsel for the Plaintiffs Executive Committee (PEC) in the Biomet M2a Magnum Hip Implant Products Liability MDL. Ward has been instrumental in assisting with the verdicts and global settlements against major hip implant manufacturers, including Johnson & Johnson / DePuy for $4.057 billion, Howmedica Osteonics Corporation / Stryker for over $1 billion, and Biomet Corporation for more than $250 million, and additional confidential settlements involving other metal-on-metal or modular-neck hip components. Ward has also been appointed to the PEC for the PPI MDL.
Before his work on PPI and hip implant litigation, Ward was heavily involved with the hormone replacement therapy litigation, representing hundreds of women diagnosed with breast cancer due to ingesting these combination hormone medications. His trial team was responsible for obtaining a $72.6 million verdict for three hormone therapy clients that went to trial. Ward was also responsible for overseeing the Meridia pharmaceutical drug litigation. This medication caused heart attacks and strokes and was heavily involved with the Cox-2 (Vioxx, Celebrex and Bextra) pharmaceutical drug litigation. His practice has also handled personal injury and wrongful death cases, including those involving nursing home abuse and neglect and trucking crashes. Overall, Ward has obtained more than $360 million for the specific clients that he has represented in the various areas he has practiced.
For his efforts in representing clients, Beasley Allen awarded him as the firms Litigator of the Year in 2013 and Mass Torts Litigator of the Year in 2011 and 2014.
In 2017, Ward received the AAJ Minority Caucus Stalwart Award for his dedicated years of service to the Minority Caucus and the organization overall. It also awarded him the AAJ Distinguished Service Award in 2012 and 2015 and its Wiedemann & Wysocki Award in 2014. Ward has been regularly selected to the Best Lawyers in America list, the Super Lawyers list, and named to the LawDragon 500 Leading Plaintiff Consumer Lawyers, the 500 best attorneys across the nation in this category.
Ward previously served in other AAJ leadership positions, including a past chairman of the Minority Caucus, past chairman of the Diversity Committee, and a member of the Board of Governors. He is a former Alabama State Bar delegate for the American Bar Association, past president of the Alabama Lawyers Association, the Alabama State Bars Young Lawyers Section, and the Montgomery County Association for Justice. Ward was a member of Leadership Montgomerys Class XXI, a former chairman of the Father Walters Charity Golf Tournament, and a member of the Alabama Law Foundation Grant Committee.
About Beasley Allen Law Firm
Founded in 1979, Beasley Allen Law Firm is a leader in complex plaintiff litigation nationwide. We work with attorneys and clients nationwide and have offices located in Atlanta, Georgia, Montgomery, Alabama, and Mobile, Alabama.Our award-winning attorneys live by our creed of helping those who need it most. For more information about our firm, please visit us online at http://www.beasleyallen.com.
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In Conversation: What everyone should know about menopause – Medical News Today
Posted: July 6, 2021 at 2:06 am
Menopause specialist Dr. Louise Newson and broadcaster Rachel New talk about what everyone should know about perimenopause and menopause.
Hot flashes, sleep problems, and mood swings these are the symptoms that many people may be familiar with when it comes to menopause.
Yet there is so much more to this biological transition that anyone who has periods goes through. When a person has stopped having periods for 12 months, they have officially gone through menopause.
The time leading up to this point is called perimenopause, and many experience a range of symptoms during this time. How long people will spend in perimenopause varies greatly from person to person.
To find out what everyone should know about menopause and why, as a society, we find conversations around womens health so difficult, I spoke to broadcaster Rachel New, who recently wrote a Through My Eyes piece about her experience of menopause for Medical News Today.
Joining us in conversation was Dr. Louise Newson, a general practitioner (GP) in the United Kingdom and menopause specialist. Louise is the founder of the free balance app, which allows users to track symptoms and changes in their periods. The app also provides information about menopause.
To hear more about menopause, including the latest on hormone replacement therapy (HRT), listen to the accompanying podcast:
This podcast is also available on Spotify, Apple Podcasts, and other platforms.
We started our conversation with Louise taking us through what happens during menopause.
Most of us go through the menopause as a natural process. Our hormones deplete because our eggs run out in our ovaries. And when they run out, [the] hormones associated with them go down, she explained.
Some women have their menopause forced on them, Louise continued.
For some, menopause happens as a result of a medical procedure, such as the surgical removal of the ovaries, or certain drugs or treatments.
The average age in the U.K. is 51, but around 1 in 100 women under the age of 40 have an early menopause. My youngest patient is 14, [and] my oldest is 92, so it can affect all women [of] all ages, Louise said.
And what about perimenopause? Louise told us that perimenopause can last several years, a decade, or even more.
[The] symptoms can start sometimes just for a few days before each period, and then it can be a week or 2 weeks, and then all the time. Its quite a transient process that often worsens with time, she said.
She listed the range of symptoms that a person can experience:
The list can go on and on and on, actually, and symptoms can vary between women and actually sometimes vary between the days and months.
Dr. Louise Newson
For some people, menopause means the end of their symptoms. But this is not the case for all.
Once a person has gone through menopause, their hormone levels will be low for the rest of their life. In some, this is accompanied by ongoing symptoms.
The average length of time for symptoms is about 7 years, but I certainly have seen and spoken to many women who have symptoms for decades, Louise explained. But symptoms change.
A lot of women find that their hot flashes and sweats improve. And then when you talk to them, theyll say, Now Ive gone through my menopause, I dont have any symptoms. But then they will say, Oh yes, but my sleeps rubbish or I have some joint pains, and I cant exercise the same way or Im just a bit more irritable, so these symptoms often do linger, she continued.
Rachel told us that she can trace back the beginning of her menopause to when she was 51. But prior to that, she had experienced problems with her sleep throughout her 40s.
I was having vaginal problems, but I kept thinking I had thrush. I was getting urinary tract infections. But it was only when I was 51 that those problems started to really bother me. I kept going to the doctor [and] being put on antibiotics for urinary tract infections, Rachel said.
Sex was becoming painful at the same time. My periods were getting closer together and heavier. Id always had quite heavy periods, but now, I wake up [and] Id flood the bed [] But I didnt know this was the perimenopause. Id never heard of perimenopause.
Rachel New
Other symptoms that Rachel experienced included itchy skin all over her body. Her GP did not mention menopause or perimenopause to her at the time.
It was only when I went and had a Mirena coil fitted for my really heavy periods [that] the gynecologists talked to me about perimenopause, Rachel told us.
Her experiences led her to set up her own podcast about menopause, called On My Last Eggs. Rachel told us that she feels her experience mirrors that of many others. Faced with perimenopause, she sought out Louises YouTube videos.
I [thought], Oh my gosh, this is whats wrong with me. I felt like I had finally found someone that I could trust the advice of, Rachel explained.
I asked Rachel why it is so challenging for women to find information about menopause. Women of menopausal age are very different from women of menopausal age in the past, she said.
Often, a woman may be in her perimenopause, [and] she may only have a 5-year-old child. She doesnt equate herself with a menopausal woman she may be at the peak of her career. She doesnt look like our menopausal mothers or grandmothers looked like, and so I think often we just dont understand, Rachel continued.
Few women are equipped with the knowledge about the breadth of symptoms that can accompany perimenopause. Add busy lives to the mix, and it can be easy to miss the fact that these symptoms must have a cause.
Louise added that there is a gap in menopause education among doctors.
I feel very embarrassed that I have probably missed thousands of women whove come to see me as a GP, telling me they have headaches, or they feel low, or theyre tearful, or theyve had palpitations, and Ive never thought about their hormones, because I didnt really know, she shared with us.
Louise missed the signs of her own perimenopause. I was busy developing and writing the content for Menopause Doctor, and I was also lecturing other healthcare professionals, saying, You must not miss the other symptoms of the menopause, she told us.
Yet I had them all but thought it was because I was working hard trying to split my time with three children, being a GP, being a medical writer, and now developing a website and trying to get a job as a menopause specialist in the [National Health Service (NHS)].
Dr. Louise Newson
So I had a lot of reason to be tired, irritable, and low mood, poor sleep, back-to-back migraines, etc. Not once did I think about my own hormones, Louise explained.
We need to be so much more open about womens health, Rachel advocated. She called for conversations about reproductive health, including periods, fertility, and endometriosis.
Louise pointed to the lack of menopause research and suggested a change in narrative.
If were not going to listen to women talking about symptoms, then we need to think about the health risks, and we need to think about the risks to the economy, she said.
Louise explained that around 20% of women either consider leaving their job or do so due to menopause. In addition, poor memory, anxiety, and fatigue are very common symptoms and can impact workplace productivity.
Its affecting the health economy, because 1 in 3 women will have an osteoporotic hip fracture, which costs the NHS 3 billion a year, she added.
Rachel encouraged everyone to arm themselves with information about menopause. She was also keen to bring vaginal health into the spotlight.
I would say to women, You deserve to have a healthy, happy, comfortable vagina [] and dont take any kind of fob off for an answer. Everyone deserves to have a lovely, happy, useful vagina that they can carry on having sex with and enjoying, and so dont be battered away from that.
Rachel New
To Louise, menopause should be on everyones radar. A lot of the work that needs to be done about awareness is [that] not just middle-aged women need to be aware, she said.
We all need to be aware: men, women, children, adults, everyone. Because we all know women, [and] recognizing [menopause] within our friends or family or work colleagues can be really important, she added.
Were new to audio on MNT and want to make sure were doing it right. Let us know what you thought of our In Conversation podcast by emailing us at mnt_editors@medicalnewstoday.com.
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Premenstrual dysphoric disorder is associated with the longer length from clitoris to urethra – BMC Blogs Network
Posted: July 6, 2021 at 2:06 am
The PMDD is triggered at times of hormonal fluctuations, in particular exposure to progesterone [1], and does not occur in the women during pregnancy and after menopause (without hormone replacement). The suppression of ovulation and suppression of the cyclical hormonal changes by the hormone therapy is the most effective treatment for PMDD [1, 18]. These evidences highlight that the direct activating effect of hormones plays an essential role in the pathogenesis of PMDD, at least sexual steroid hormones, such as progesterone, may precipitate the presentation of PMDD. Moreover, the very early organizational effect of prenatal sex hormones that may contribute to the PMDD has recently got attentions. The previous work using the 2D:4D ratios as a marker of prenatal sex hormones exposure, indicated that the prenatal sex hormones exposure might influence individual differences in the severity of premenstrual symptoms [9], and could be a factor in the development of PMDD. A recent preclinical animal study clearly showed that prenatal androgenization induced anxiety-like behavior in adult female rats, implying that prenatal exposure to high concentration of testosterone might influence the development of neural networks and impose the risk of anxiety-like behavior later in life [19]. We measured the 2D:4D ratios, AGD-AC, AGD-AF, and CUMD of the subjects, and found that the left/right 2D:4D ratios, AGD-AC and AGD-AF did not show any difference between PMDD patients and controls, but a significant longer CUMD was seen in the patients with PMDD. The CUMD, as well as the 2D:4D ratios, AGD-AC and AGD-AF, is supposed to be positive association with prenatal androgen levels, therefore, our results supported that atypical high prenatal androgen exposure might predispose individuals to be susceptible to PMDD.
We did not detect the current level of androgens in the patients with PMDD. An early research reported that serum levels of androgens were higher in women with premenstrual irritability and dysphoria than in controls [20], but other studies had shown that plasma testosterone in women with premenstrual symptoms was not different from that in non-symptomatic controls [21, 22]. A recent study which carefully investigated the level of androgens in women with cyclical mood changes and premenstrual syndrome demonstrated that plasma testosterone was significantly lower in women with luteal phase symptoms compared with those with additional follicular phase symptoms [23]. The PCOS is a hyperandrogenic, oligomenorrhea/amenorrhea, fertility problems and metabolic disorder found in 67% of reproductive-aged women [24]. Therefore, the clinical features and pathophysiological processes of the PMDD should be totally different from ones of the PCOS. Recently, several studies demonstrated that AGD in adult patients with PCOS was longer than that in control, implying that extreme prenatal androgen exposure might contribute to PCOS [16, 25, 26]. Whereas, our PMDD patients showed elongated CUMD, rather than extended AGD. It seems that both of PMDD and PCOS are probably involved in the higher prenatal androgen exposures. But, why did PMDD patients have a longer CUMD and PCOS patents have a longer AGD? Future studies are awaited to help delineate the difference. At present, it can be inferred that there are other factors led to discrepant perineum appearances, in addition to prenatal androgen hormones.
Several reports demonstrated that the presence of premenstrual symptoms correlated negatively with sexual satisfaction [23, 27,28,29]. Sexual pleasure and orgasm during copulation in women depends on many factors, such as past experience, stimulation of one or all of these triggering zones, autonomic arousal, and partner- and contextual-related cues, etc. [30]. The clitoral complex in relation to the urethra, vulva, and vagina is the essential sensory triggering zone [29]. A longer CUMD in a woman decrease her likelihood of experiencing orgasm in sexual intercourse, as the longer CUMD may decrease penile-clitoral contact during sexual intercourse or decrease penile stimulation of internal aspects of the clitoris [12]. Therefore, the longer CUMD might contribute to the sexual difficulties of women with premenstrual symptoms, according to our results.
There are some major defects in the present studies. This is a preliminary study with limited samples that were not chosen randomly, the way of collecting cases could lead the bias to some extent. Moreover, we did not study the association of individual differences in the severity of premenstrual symptoms with the left/right 2D:4D ratios, AGD-AC, AGD-AF and CUMD, and did not collect data about the sexual function/satisfaction of subjects, at same time.
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People come together to fund hair removal of Gaurang aka Prakriti, so that she feels complete in her identified gender – OpIndia
Posted: July 6, 2021 at 2:06 am
Fundraising platforms in India have helped people in need of medical treatment or other financial needs, and now this spectrum of public help appears to be widening. One particular call for public help caught the attention of many on social media earlier today was where a person started a fundraiser for hair removal.
The fundraiser was started by a Bangalore based person Prakriti Soni, who needed funds for hair removal as the financial condition of the family was not stable.
While hair removal might sound too mundane a thing for which a fundraiser should be started, Prakriti explained that it was nothing less than a life altering procedure for her, who is 21-years-old and identifies as trans-woman.
She explained that she must get rid of the hair on her body to remove the mismatch between her biological sex and her gender identity. This mismatch was majorly affecting the mental health of Prakriti, giving her distress and discomfort something that is known as gender dysphoria as Prakriti explained in her fundraising page.
She said that the Covid-19 induced lockdowns were making her gender dysphoria worse and thus she has decided to completely remove the body hair via laser treatment. Since her own or her familys financial condition is not stable, she decided to seek public help, and it appears to have worked for Prakriti Soni, who was earlier Gaurang Soni.
To support her claims, Prakriti uploaded a doctors letter from Ramaiah Memorial Hospital of Bangalore. The letter stated that the client refers to themselves in the feminine gender and to respect their feelings I will be using female pronouns throughout this report.
Doctors letter identifies Prakriti as a male to female transgender person who had described a desire to be and to be treated like a member of the opposite sex since early childhood. It also states that her family is supportive of this and so is her social network, which reflected in the fact that Prakriti was able to raise more than half of her targeted fundraise.
An anonymous person who helped with 5000 rupees, the maximum individual contribution at the time of this report being published, left a message that read Hi Prakriti! Wish you all the very best. I wish you are able to meet your target and get your hair treatment done and feel better!! You are an amazing person and deserve the best!!
Another contributor, who identified himself as Adil, said, I am a friend of Nikita whose friends with mridula. And I cant tell you how happy I am for you and hope that everything works out fine (sic.)
The doctors letter dated 28 October 2020 report said that Prakriti reported gender congruent experience of living like a woman for the past two years. It further revealed that Gaurang alias Prakriti liked being with and playing with girls in the school, and also acted like them.
She wants to get rid of both primary and secondary sexual characteristics because of the marked incongruence she experiences. She seeks hormone replacement therapy to feminize her body to suit her gender identity, the doctors letter declared.
It is not clear if Prakriti has already undertaken hormone replacement therapy or she might need another fundraiser for that. However, the hair removal fundraiser was on track.
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People come together to fund hair removal of Gaurang aka Prakriti, so that she feels complete in her identified gender - OpIndia
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You could be going through the menopause for YEARS without getting help these are the signs… – The Sun
Posted: July 6, 2021 at 2:06 am
WOMEN are going through the menopause for years before receiving the help they need, a shocking survey has revealed.
Symptoms of hot flushes, fatigue and depression can be managed. But many women are not getting access to drugs.
3
Some women said they had visited their GP several times without any progress.
The menopause is when a woman stops having periods and is no longer able to get pregnant naturally due to depleting levels of oestrogen.
But the hormone rollercoaster that comes with it leaves women with debilitating symptoms for up to several years.
These can start years before periods stop, known as the perimenopause, meaning some women may not even realise it's due to the menopause.
On top of this, campaigners say GPs are not trained sufficiently to spot the signs or treat women appropriately.
Menopause is a natural part of ageing, which usually happens when a woman is between the age of 45 and 55.
In the UK, the average age for a woman to go through menopause is 51, but it can start as early as the 30s.
The severity of menopausal symptoms can vary depending on the individual.
They can range from mild to significantly interrupting your daily routine.
Menopausal symptoms can start months or years before your periods stop, and can last until four years or longer after your last period.
Symptoms include:
The new survey, carried out for menopause medic Dr Louise Newson, who runs the not-for-profit Newson Health Research And Education, highlights the delays women face.
Of the 5,187 women surveyed, the majority (74 per cent) had been experiencing menopausal symptoms for more than a year, while 15 per cent said this had been the case for more than six years.
Some 79 per cent of women had visited a GP with their symptoms.
A shocking seven per cent attended more than 10 times before receiving adequate help or advice.
Some 27 per cent of women said they had also seen more than three doctors in hospital about their symptoms, even though in most cases, they can be managed by a GP.
Of those who did undergo treatment (33 per cent of all the women surveyed), 44 per cent had waited at least one year, and 12 per cent had waited more than five years.
3
Of those given treatment, 37 per cent of women received hormone replacement therapy (HRT) and 23 per cent were given antidepressants.
Guidance from the National Institute for Health and Care Excellence (Nice) saying women should not be prescribed antidepressants for symptoms such as hot flushes and night sweats.
Dr Newson said: This is a huge waste of NHS resources, including increasing the strain and workload to primary care not to mention womens time.
Since May of this year, we are seeing a greater appetite from medical professionals, especially in primary care, to learn more about managing the menopause. This cant come soon enough for women who are struggling.
A separate survey of 1,096 women by Mumsnet and Gransnet found that 14 per cent have found it difficult to get their GP to prescribe HRT.
Dr Edward Morris, president of the Royal College of Obstetricians and Gynaecologists (RCOG), said: It is saddening to see the ongoing challenges that women are experiencing in the diagnosis and treatment of the menopause.
There is no one size that fits all when it comes to the menopause. This is why it is crucial that women have access to reliable, accurate education and information so they are made aware of the options available and can make informed choices about their health.
While access may vary, we want to reassure women that most GPs are very experienced in offering menopause care, and can refer women to specialist menopause services where necessary.
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Judith Cummins MP: ‘Patchy recognition, support, and treatment for menopause is unacceptable’ – Bradford Telegraph and Argus
Posted: July 6, 2021 at 2:06 am
MUCH of the work of Parliament is done through All-Party Parliamentary Groups (APPGs).
I chair a number of these groups including the Rugby League APPG.Telegraph & Argus readers may have seen that as the Chair of this group I spoke to the Rugby Football League and helped overturn their decision on ceasing to fund the Bradford Bulls Elite academy.
In this article I will share some other work that I am doing through APPGs.
I am a member of the newly-formed menopause APPG. Menopause is a health issue that affects almost one fifth of the population and that half of us will directly experience at some stage in our lives.
Often misunderstood, misdiagnosed and something of a taboo subject, approximately 13 million women in the UK are either perimenopausal or postmenopausal.
The menopause is a natural part of ageing that usually occurs between the ages of 45 and 55, as a womans oestrogen levels decline.
While some women barely notice any changes, for others the effects on their health and wellbeing can be devastating affecting their careers and ending relationships. And yet, recognition, support, and treatment are patchy at best.
This is unacceptable for a health condition that is set to impact half the population. I am co-sponsoring a Bill in parliament on menopause support services and to exempt hormone replacement therapy (HRT) from NHS prescription charges.
Too many women are suffering unnecessarily, trying to cope with extreme symptoms without the correct treatment and support.
Even when it is correctly diagnosed, women still face barriers to relief.Treatment, often in the form of multiple medications and HRT, has a hefty price tag.
The Bill aims to resolve this so that women get better health guidance, improved recognition from their doctors, fully funded HRT treatments and changes in the workplace.
In a related move I am co-chairing a newly formed APPG on osteoporosis and bone health with the support of the Royal Osteoporosis Society (ROS).
This is to raise awareness, influence legislation and improve the lives of people living with the condition.
There are 3.5 million people living with osteoporosis in the UK and it results in over half a million broken bones every year, this is also a condition that is rarely talked about and often goes undiagnosed.
Everyone loses bone density and strength as they get older, but women lose it more rapidly in the years following the menopause.
With that comes a greater risk of breaking bones.
According to the ROS, a fifth of women who have broken a bone, break three or more before their osteoporosis is diagnosed.
Through the APPG I will be pushing for earlier diagnoses to help prevent that first fracture as well as the important preventative work and treatments for bone health.Beauty and wellbeing businesses are the lifeblood of our high streets.
It is an industry predominantly run by women, for women, employing women.These small business owners, local entrepreneurs, are part of an industry that contributed up to 30 billion a year to the national economy.
The APPG on Beauty Aesthetics and Wellbeing, which I co-chair, has been leading an enquiry into non-surgical cosmetic procedures.
Worryingly, it has found massive growth in short courses for advanced procedures such as injectables including fillers and Botox. These are complex aesthetic procedures that cant be taught in a day.
A lack of national regulation around this ever-growing list of treatments available means that consumers cant have the confidence that their treatment is being administered by someone properly trained.
Alongside Laura Trott MP I have been working hard on outlawing injectables to those under 18.
To make sure that standards are lifted across the beauty industry, a certificate on the wall isnt good enough.
Thats why in Parliament I have called for the government to strengthen regulation and training for non-surgical treatment.Its what the public expects and what the government needs to deliver.
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