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Category Archives: Louisiana Stem Cells

Penn Oral and Maxillofacial Surgeon Driven by Desire to ‘Make Someone Whole Again’ – Penn Current

Posted: August 31, 2017 at 11:44 pm

In his office at the University of Pennsylvania, oral and maxillofacial surgeon Rabie Shanti sits at his computer, clicking through photos of patients hes operated on.

He pulls up an image of a mouth open wide, tongue extended.

This is a recent case, he says, pointing to one side of the tongue that looks slightly different from the other. This is forearm skin with an artery and vein taken from the arm. That surgery was done the same day the patient had their tongue cancer resected. We used those tissues and vessels to reconstruct the tongue to allow this patient to maintain their ability to eat and speak after having almost half of their tongue removed.

Those familiar with grafting surgery may understand that, after a burn, for example, surgeons can take portions of skin from one part of the body to replace skin lost from another area. But what Shanti is describing is something even more mind-bending. He reconstructs tongues, as well as other portions of the oral cavity, using tissues and bone harvested from other parts of the patients own body.

The work is remarkable, but taxing for the patient. So when hes not busy in the clinic, Shanti, who joined Penns School of Dental Medicine as an assistant professor last year, is devoting energy in the lab to better understand what drives oral cancers and to design new structures that will more effectively replace the tissues his patients lose during surgery, whether due to cancerous or benign tumors, trauma or inflammatory conditions.

I think that I was always fascinated with the idea of putting something back together, says Shanti, who also holds an appointment as assistant professor in Penns Perelman School of Medicine. Most of what is done in dentistry is really reconstructive, whether its rebuilding the tooth surface or part of the jaw.

When Shanti was a college student at Florida Atlantic University, he became interested in pursuing dental medicine as a career, though being a surgeon was not on his radar.

At that time, aside from having braces, I had no deep experience with dentistry, he says. I thought I wanted to be an orthodontist. I didnt know what an oral and maxillofacial surgeon was until I was in dental school.

He attended dental school at Harvard University, pausing his studies to spend two years as a Howard Hughes Medical Institute research scholar working in an orthopedics laboratory at the National Institutes of Healths National Institute for Arthritis and Musculoskeletal and Skin Diseases. The lab was headed by Rocky Tuan, who is now at the University of Pittsburgh. At the NIAMS, Shanti delved into tissue engineering, focusing on designing new materials to help regrow muscle and bone.

I quickly noticed that my research interests were fueled by my clinical interests, and one area that really interested me was reconstructive surgery of the jaw and tongue, particularly reconstruction for pathology, he says. Seeing someone who had a benign tumor or cancer that involved their upper or lower jaw bone, and now theyve lost that part of their body, but being able to make someone whole again, that really drew me in.

After completing his dental degree, Shanti went on to pursue his residency in oral and maxillofacial surgery at Rutgers University, an experience he likens to being a kid in a candy store, enticed by all the possible areas in which to focus. He earned his M.D. at Rutgers along the way. He then went on to Louisiana State University for a two-year fellowship, pursuing research and bolstering his experience in reconstructive microsurgery, which involves taking tissues and blood vessels from one part of the body and connecting them to another part of the body to make it a living tissue. Shanti left LSU for Penn in 2016.

Through much of his training and still today, Shanti has pursued research in an area that sparked his interest early on in dental school: ameloblastoma, a rare tumor of the jaw, affecting 1 in 2 million people. This tumor type is resistant to most forms of treatment, leaving patients with surgery as the only viable option. These procedures often result in the loss of large portions of the lower or upper jaw.

Shantis investigations have examined the role of mesenchymal stem cells, which dwell in the bone marrow, in supporting ameloblastoma tumors. Working with his research mentor, Anh Le, the Norman Vine Endowed Professor of Oral Rehabilitation and chair of the Department of Oral and Maxillofacial Surgery/Pharmacology at Penn Dental Medicine, Shanti has looked for ways to disrupt the communication between these stem cells and tumor cells as a way of possible preventing their aggressive growth.

A second research interest for Shanti is tissue engineering, specifically to improve tongue reconstructions. The tongue can be affected by invasive squamous cell carcinoma, and to treat it can involve removing large portions of tissue. Shanti works closely with Le in her lab at Penn Dental Medicine towardengineering constructs that could help a patient regrow tissue rather than using tissue taken from another body part.

I think were on the cusp with tissue engineering and using engineered stem-cell-based constructs to reconstruct tissues of the head and neck, says Shanti. I think thats going to be a really significant advancement in reconstructive surgery that I hope to be a part of during my career and lifetime.

In the clinic, Shanti alternates time seeing patients at the Hospital of the University Pennsylvania and Pennsylvania Hospital, working with colleagues to address the diverse needs of his patients. He notes that the comprehensive and collaborative care offered by Penn was part of the appeal of joining the faculty here.

For patients with head and neck cancer, the part of the body that is affected, our face and head, is not only part of our identity, but it has significant functions, Shanti says. Penns Abramson Cancer Center, of which the faculty of Penn Dentals Department of Oral and Maxillofacial Surgery are part, brings all the specialists together to get these patients back to their day-to-day. Our team includes surgeons, radiation oncologists, medical oncologists, nurse navigators, speech language pathologists, nutritionists, social workers, oral-medicine specialists, prosthodontists, and we all go over each case together. Its patient-centered rather than practitioner-centered.

Shanti has seen a lot of progress in his field. Today, hes able to plan out surgeries thoroughly in advance using digital tools.

I can get on a computer with images of the patient, design the surgery, simulate it and identify where Im going to make the cuts in bone, how the tumor is going to come out and how Im going to rebuild it, he says. Then Im provided with customized materials, cutting guides and plates designed specifically for the patient. It not only helps increase the precision and accuracy of the surgery, but it also minimizes the time we spend in the operating room because were not doing that guess work thats already done.

Still he feels there is a long way to go.

Describing another case, Shanti this time shows a photo of a bright, healthy-looking smile.

This is from a patient I saw Monday, he says. She had an ameloblastoma and we did a computer planned and customized free-flap reconstruction using bone and skin from her lower leg. She has a dental prosthesis and is doing well.

Shanti hopes it wont be long before many more patients will be able to arrive at this stage, with fewer invasive procedures.

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Penn Oral and Maxillofacial Surgeon Driven by Desire to 'Make Someone Whole Again' - Penn Current

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BACK IN ACTION: Stem Cell Knee Procedure Gets Middle Aged Athlete Back On Slopes, Court – SpaceCoastDaily.com

Posted: August 28, 2017 at 10:44 pm

REGENERATIVE MEDICINE STEM CELL THERAPY

DR. JOHN HERMANDORFER, above left, harvested cells from Giles Malones left tibia, and injected these into Malones left knee. As Giles Malone, above on the ski slopes of Utah in January, sprinted into his 50s, he began noticing that his knees were getting sore with his active lifestyle. Unfortunately, the years finally decided it was payback time for all that stress on his knees.

BREVARD COUNTY, FLORIDA As Giles Malone sprinted into his 50s, he began noticing that his knees werent keeping up with his active lifestyle.

Malone, a partner/owner with Maverick Multimedia and Brevard Productions, is an avid weekend make it weekday warrior who cant get enough of skiing, tennis and golf and working out at the gym.

The avid athlete played soccer for Bristol City youth in England and at the University of Louisiana.

He was an intergral part of the coaching staff with Florida Techs soccer team, which won two NCAA championships. Unfortunately, the years finally decided it was payback time for all that soccer on his knees.

My left knee would be sore after working out several days in a row, said Malone. I have lots of mileage on that knee.

Giles Malone, (#8) was an avid athlete playing soccer for Bristol City youth in England, Cocoa Beach High School and at the NCAA Div. 1 University of Louisiana. He helped coach Florida Techs soccer team to two NCAA championships. Unfortunately, the years finally decided it was payback time for all that stress on his knees.

His 85-year-old father has had both knees replaced, and his 61-year-old brother has gone through the procedure once. Malone wanted to stave off, or possibly nix altogether, the possibility of a knee replacement, so he turned to treatment that is less invasive and much more holistic.

Being familiar with the success stories from the many people who have received treatment from Dr. Hermansdorfer, I opted to go the route of stem cell therapy, said Malone. This could save my knees later in life.

Malone was also impressed that Dr. John Hermansdorfer, who has a well-deserved reputation of excellence in traditional orthopedic procedures, would be handling his case.

The fact that these physicians with stellar reputations believe in stem cell therapy, tells me that this is a really viable option, said Malone.

Hermansdorfer has done extensive research on regenerative medicine.

Hermansdorfer, a 1982 graduate of the University of Kentucky Medical School, completed his residency in orthopedic surgery at the University of Florida and received fellowship training in hand surgery at the Indiana Center for Surgery and Rehabilitation of the Hand in Indianapolis.

DR. JOHN HERMANSDORFERs treatment was performed in conjunction with a knee arthroscopy, a surgical procedure that allows doctors to treat the joint without the need for a large incision. Hermansdorfer debrided damaged cartilage from the patients knee using miniature surgical instruments, at left, inserted through an arthroscope, an instrument about the diameter of a soda straw and fitted with a miniature camera, a light source and precision instruments at the end of flexible tubes.

HIGH OCTANE AMNION CELLS

Recently, Malone underwent the elective procedure, which harvested cells from his tibia, and injected these into his knee.

The treatment was performed in conjunction with a knee arthroscopy, a surgical procedure that allows doctors to treat the joint without the need for a large incision.

Hermansdorfer debrided damaged cartilage from Malones knee using miniature surgical instruments inserted through an arthroscope, an instrument about the diameter of a soda straw and fitted with a miniature camera, a light source and precision instruments at the end of flexible tubes.

It was not just one procedure, but a combination of procedures to obtain optimal results, said Hermansdorfer.

Malone was the perfect candidate for the stem cell procedure in strong physical condition, with the knee in solid shape just lots of mileage.

He is the typical middle-aged athlete, said Hermansdorfer. When they get older, these individuals start to pay the price.

Before the advent of stem cell therapy, options for Malone would have been minimal.

This is a much better option than pills or cortisone shots, which can have a damaging effect over time, said Hermansdorfer.

Malone is not alone in his pain. Joint and spinal pain are a common complaint, and invasive surgery for these issues requires significant downtime with true success often elusive.

BioCellular Therapies regenerative cell treatment, on the other hand, is a kinder, gentler and definitely viable alternative for individuals suffering from osteoarthritis, degenerative disc disease or sports injuries.

Regenerative cells repair muscle, tendon, ligament and cartilage and they do it quickly.

There is no question it works, said Hermansdorfer. Research shows good results. It enhances cartilage growth, which allows us to move our joints without pain.

Interest in this type of treatment is so high that individuals from outside the United States have scheduled treatment with BioCellular Therapies, located in Melbourne.

We have had patients from their teens to their 80s, said Hermansdorfer. Its so simple, its so safe.

However, not everyone is an appropriate a candidate as Malone was.

Age of the patient is not an issue, but rather the severity of the problem, said

Hermansdorfer, recounting an 80-plus-year-old patient who was also a perfect candidate because the cartilage in her knee had not yet been worn down beyond repair.

We have to have a reasonable amount of cartilage left.

SPACE COAST DAILY TV MEDICAL SEMINAR SERIES:Dr. Mark Pinsky and Jim Eaker,experts at BioCellular Therapies in Melbourne, Florida, talk with Giles Malone about the revolution in contouring and tightening your face, neck and body; and body rejuvenation, including the Vampire Facelift and Breastlift, and the O-Shot.The pursuit of youth and beauty has become an easier journey along the Space Coast with the introduction recentlyby BioCellular Therapies of the Vivace RF microneedling system, used in conjunction with amnion-based gels and creams for optimum performance in promoting the development of collagen for easing fine lines, wrinkles and uneven skin.

RAPID RECOVERY, LITTLE PAIN

For the arthroscopy and stem cell therapy, Malone arrived at Atlantic Orthopedic Surgery at 9 a.m. By noon, he was home. Afterwards, he needed no pain killers other than Tylenol. Although he used a cane for a couple of days, he soon ditched it.

There was little down time, he said.

Because of the arthroscopy component, Malone opted for general anesthesia, but stem cell treatments can be performed in an office setting under a local block.

Six weeks after the procedure, Malone should be back to participating in the sports he loves. The two small incisions required for the arthroscopy already are now invisible. Another of Hermansdorfers patients, a marathon runner, returned to marathons six weeks after receiving the stem cells.

Compare Malones experience with that of a patient undergoing knee replacement surgery. The individual is expected to be on crutches for six weeks. Pain can be significant, too.

Not only is downtime for stem cell therapy almost non-existent, but it is also a quick and painless endeavor. Harvesting and mixing the cells requires minimal time.

It just takes five minutes, said Hermansdorfer.

The cells are reinserted into the patients body through micro-fracturing.

They do tiny holes in the bone so it better accepts the stem cells, explained Malone. I compare it to turning up the soil to better grow plants.

Using the super cells found in the patients own bone marrow optimizes healing and reduces risk.This is so much more natural medicine, said Hermansdorfer.

BioCellular Therapies is at 2290 W. Eau Gallie Blvd., Suite 210, Melbourne. For more information on the practices hair restoration services, call 321-435-1505 or visit BiocellularTherapies.com

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BACK IN ACTION: Stem Cell Knee Procedure Gets Middle Aged Athlete Back On Slopes, Court - SpaceCoastDaily.com

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Flash Flooding Begins – WWL First News

Posted: August 28, 2017 at 10:44 pm

And welcome back to our show how we had just a few minutes ago some really heavy rain in downtown New Orleans there's a lot of heavy rain to how this part of the country as you know. If you really be careful eye she won over on and you can safely do it semi Texan let me know if you see some flooding we're getting floating. Our reports from all over the area so far system minor a street flooding but you gotta be careful I wanna mention that if any time during the show this afternoon. I you catch me going there. Is because I pulled. Apple the muscle my back. During during during sleep last time and mostly to. And I remembered the dream I just didn't remember that it caused my muscle to report in my back anyway columns so I'm. Went to golden year on the air on the saints looked good Saturday night especially the defense Ted Ted Ginn junior looked really good. Our camp Jordan. Our rankings Latimer Williams on defense looked good I was impressed with secretaries of Victor. So you know there's reason to be very optimistic about. About the saints and also this was a really last minute thing mine Andy's celebrated her thirtieth birthday in New Orleans over the weekend. I believe me it was an entire weekend's worth of of celebrating. She lives in LA now and she was in town with her boyfriend. And her boyfriend's parents. And so was really interesting and being in in New Orleans and and going out and doing things. With a couple from LA a very well travels couple from Los Angeles. They were so enamored with our city. The husband had been here once on business but never really got into the culture. And that's what I kept hearing all weekend long house special New Orleans is we've got our problems. We know what those problems are gonna do a better job of of Hanley. But there is something so special. About displace. And and southern hospitality. Is three. It's sometimes hard to put into words. But you experience it you sensed it you feel it and I was really proud of the city this weekend here this this couple from LA and just talking about how wonderful the Avant around the city is so anyway so my brother and this whole group of people like there's like eight or nine of them. They they're leaving the saints game they wanna go some remarks to McGregor Mayweather fight. And they can't find a suitable place to go watch it so they symbol if we come to your apartment downtown will pay forty if you if you get the fight so again. A Tomasson I've got no snacks for companies so you better pick up some things on the way over here but I watched the fight and it was entertaining went into the that the tenth round and it was pretty obvious that McGregor was just going to. Burnout at some point and he just kind of got to be a little punch drunk some people were critical about when the officials when the referee stopped the fight but I thought at that point. It was time to Politico. So as the floodwaters rise in Houston and alarm goes off in us. It's at sites alarmed that terror alerts us to our own humanity. You were greatly divided society. But we tend to put politics aside at a time like this. And one help each other. And people are helping other people not caring if they're Republicans or Democrats or white or black her. Christian Jew or Muslim. They're helping them because they're human beings. And since we're so divided I think we need to celebrate moments like this it and and recognized these moments when we do come together. And to cajun navy is I headed over to Houston a big can groove protecting may be on the road right now. The cajun navy guy appoint 1 o'clock pulls on the Costco in Baton Rouge and there were other members as the cajun navy already in the Houston area. These scenes that we're seeing from Houston are. Are haunting. Because soon so many of you have gone through that kind of horrific flooding risks Katrina. And sometimes we've had bad flooding when it's just an afternoon. Thunderstorm last rumors it was August 5 so flooding is something that is common to the area. Here's the problem with mayor land for. He says the pumps I think the last word I got to win for his was 93%. Capacity. Really. Here's the problem with lying to people. Do you believe him. Mean is it really 93% meet first remember all the pumps were were working and now the mayor did say at but the city said it. Sewage water board to the city said all the sponsor were to all the known no wait a minute now there's sudden six or seven out and we will find out what they were sixteen. Something like that pumps around. This is the problem with not being honest with the public. If it in vector telling the truth. We don't know if we can believe it. And that's when it comes to the little stuff I'm gonna bring this up not to resurrect this topic but to just point out how the little things are important. When you say you're going to treat the monuments a certain way and you don't. And there's a visual evidence that you're not doing it. The city loses faith citizens lose faith in you. And so you know what honestly when the mayor says so I I hope he's telling the truth. But when he says something now we don't know because there has been a long history of covering up reality. At eEye I don't mean to. Getting to know at this point but I mean that's that's why it is so important to tell the truth and be honest about even the little stuff. Stop trying to protect your political image. And I'm just talking about America not all. Stop trying to protect your political image and be honest witness. Because if you don't whenever their belief. If you would like to join us with comet this afternoon about flooding that you have done to prepare yourself for anything that's going on with. This. Is this the storm. Where he is associated with party. And some of these bands we do we knew they were coming. Moving toward the east and were expecting some heavy rain. Right now in it and we had I mean. Blinding rain. Under and you need the unit. But he stopped him town which is good. It's wait continues extended period of time. We have some problems. Telus. It's obvious it's not to full capacity. That's a reason for concern. Were things in certain ways like. With the statement is about 93% capacity. They might be capable of doing 93% does that mean 93%. And that somebody else a chance to pay attention to when politicians speak. If you don't like to join us with your comment this afternoon our numbers 2601. Saturday. Perry coach final four to six so 170. Tex Amber's age 7070 Texas senators Ted Cruz and John Cornyn in a January of 2013. They voted against. An aid bill following super storm sandy. Now they won eight for Texas. Yeah it's really easy to say you're not gonna give aid to somebody else the thing you want it and that happened here in New Orleans. A lot of people in the area affected by sandy. Had them don't even give New Orleans money to rebuild. Its a waste of time don't just fought again. But what happen to them. Now than they want a date and also to some Texas senators say they wanna get a after super storms sandy but now they want aid. Deal love the hypocrisy of politics today. Our numbers 2601 A somebody text based Seve seventy. I've skirts and we'll be back I don't have Euro. That is just amazing to see those scenes from from Houston. And we can so relate to them we've also this afternoon the talking about tell the LSU BYU game. Obviously the game cannot be played in Houston this weekend. Should be New Orleans. Will it be enough going on here that we should not to encourage people to come to. The city. Of the weather supposed to be better by the weekend but is it still going to be. Sketchy enough to where we should know to gain this weekend would you run of the game be played. In Utah. And BYU tiered LSU fan cannot be played or all of our our postponed. I know everybody's ready for the season beat to get started I mean you talk obviously would give the placed at passing game. Now this is not up to L issue it's not up to BYU apparently this is up to ESPN. And as far as I know no decision has been made. I am getting a number of text about flooding. In late Q and there are some areas of Florida again the rain downtown has has so lighten up a lot. How bite do you might be some heavy rain right now so we'll continue to work just update you is desperate channel everything was going on this afternoon. From Chantilly Jack DC any flooding in your neighborhood. Yeah I'm standing here looking at to catch basins that are reported on March 3 at this year. As 1521. In 1520. Minutes or street. And nothing has happened nobody's been out in the war as competent. Stay. Aren't they aren't they on they are they've they've broken destroyed or just covered with the stuff. I don't know what they're covered with but the water's just sitting here. Now as his attorney your house. One social. Terry have you gone out to look at him. OK so you don't see any debris. I'm not gonna stick my hand down and. I thought nobody you don't usually see any any I heard before they before they they think flooded you didn't see debris I mean there was nothing for you to clean up. The types that you feed into the and Serbia gets stakes. But I mean it's ridiculous made these boat that these catch basins were reported. And nobody's standing at six. I wish I had better news for you other than to say welcome to New Orleans. Oh we've been just 1850s so when that going and. All know it's it's it's true doesn't mean we're not gonna endure some he continues his jagr appreciate I mean I just I don't even know what to say about it. Terry this this city is. For too long. The city's paid attention to the cosmetics. For the terrorists. Everything for the tourist. And less concerns about the citizens that put the people in office. It's tragic. For Blake do you Brian do you see any flooding. 3%. In trouble. Which is a gang is going to what you lot. It didn't mean to it. And street. You know that. Twenties in the thirties and lastly you. Therefore especially on the and if flooded and in the during you know I'm responsible. Well. So the question. You wouldn't. And an outlook now streak right now in the thirties. It all the way off. 200 yards. Across should be. When I have been to gain. One mystery 34 inches of rain a street like a couple. Straight up straight now. Not totally in trade across the street out there bulk to orient to vote now in on the on the on the north side that I'm. I'll call on the right see on the miles wants to. He's lines it is and it isn't it before. And I don't. Vote. Yeah I don't worry I don't know where at a Hillary gets to figure and and that the problem is because of the history of what we have been told there's no reason. To believe him which is really the tragedy of lying to the public. Well here in the bank. So if there's power came an average do when tropical storm now is being manned heritage or over to. If I. Can't. By the close. This is truly a ruling like that in the long balls on the wall and brain you're seeing. Now. And the return and it does it's kind of street and what can you own. Not an somebody somebody from a guy coming in and take this'll on this clown. That we elected. I'll vote orange be the first person as a the point is they'd go from there it looked into it because these little political. And understand. Is that not all it's April. You gotta be in jail people who are trying to make things. I'll lay. Oh well you know. Money via play a tax money that somebody come out here and tell of people are true. If range story edges you're gonna fly I'd probably it. Listen Brian I I hear your passion and listen good good luck and good luck if you're in one of those areas that is really prone to to flooding in their look there are areas around the city like that. A from Hammond doctor Dan welcome Debbie WL. Yeah you don't care who I'm good. I do I do or man. Well you know sometimes rain is is good we don't need too much of it. Good or Derek Lowe and appliance. Yeah all of your. Good lord is good for there is good for the corn and the corn is used to make was susceptible to find something good about that. Yeah well I think there I'll let you BYU game should be played in the superdome and at all. Yeah that is so that has come object doctor Dan. I guess the issue is what's it going to be like here. And as those who would come to the game here from say Baton Rouge what's it going to be like in Baton Rouge. What's going to be like in areas of Louisiana don't draw a big crowd here should we ask. That group of people to leave their home look. We don't know what's gonna happen yet there's a better chance of rain tomorrow and Wednesday. And there is today. And right now radar is discovered we showers throughout the Syria is some of its heavier and others. Got to Texas says son elm wood Joseph what's flooded pretty bad side streets are still flooded. And other text says clear view and Elmore and I was flooded you know that that's an area that is is prone to flooding. I mean there's some areas that start to Florida soon radiator. You know over. Overheated skills and her into the street so when you get a good rained any there's going to be some some flooding. But we've obviously got some pretty serious problems that have not been attended to. And that's a problem. I even think we would get into politics this afternoon but when. You know the problem with lying is in deceiving the public is that when you say something we don't know whether to believe you. That's the danger effect. Crimes coach if you wanna join us 260 when he separate text they 7870. Now announce at a three say don't. I'm we'll see where it goes from there parent is due process. Price of the little more. Are right now let's go to to. The communications director for the governor's office of homeland security and emergency preparedness. It's my XTO joining us and every of your own my good afternoon. Good afternoon I'm normally Johnny Cash for him but I don't know that well. Well today it is a little bit of a realism much of that song. Like I tell us about it in particular resident of the city of New Orleans and no but you know. Well we're seeing you know some. Lotto ball street what information coming in obviously work. Kind of moving into the bowl done now is this system continues to move on east we still haven't really received any call me initial court. I'll from the city at this point so what we're taking their kind of as a good sign by. We have step there are new pima has stamp the year party reacted in Ecuador steps need to be dark. By right now which is kind of you know Wilma triple Wi fi would be worst impacted areas are gonna be is these storms. Speedo wearing pairing and continue to come Peru. Are you in just you were to adjust to whatever. You are what are you know about southwest Louisiana and they've been getting pounded for Lisa last day. Right that's absolutely right worse in this situation now where are coming impacted arms. Some of that kind of going away is wearing. Slacks all for a little while these words become better. The fear that their kind of primary concern now because of BP. Just some beer potential and that area. But we've gotta be repaid reacting anywhere in the state you know not just what you want Spain or late trolls. Disparate gonna grew up in the central Louisiana and even north Louisiana. They're seeing some of these wing it could lapse between old next. True you know this is going to be in the very extended. Disaster to deal with the you know we forties and resources are detection and help him now. As the ball their great support for Austria over the years. But you know we got them manage all these things and small weight we don't we cells vulnerable crops such. Well what do you know about pumping capacity in New Orleans. All the odd. I don't have the exact asking is for like what they're percentages or. You know the should be has been supplying information. Routinely too much. With I don't know what all included in this information directly. Aren't there in place to use a mother's decision be made local mobile phone with the arsonist. Would. I mean are we can't speak to them. You know Udell. And there's been a lot of communication going all our staff is down there you know ready to help that we just seventeen this situation yet. Where any actions name were quark for state resources that our rule. And giving them to reduce process that it and it doesn't matter what the reason there's so that's important for people to understand we have to be party. Just what state resources no matter what the situation as what type of emergency he has been being wiest in liberty to do. But you feel totally confident that the information do you have about because. Ultimately he Europe you're part of the state door was as part of the state so was part of the homeland security and emergency preparedness. You have a vested interest in what's going on in New Orleans. On the capacity that the mayor has given you and you have every reason to believe that that's realistic and not politically driven. I haven't heard any reasons for our suit to examine reasons not to trust the information coming out soon. At all in Iraq and speak. Out and hurting these discussions about being in a problem. With the trust. What do you want people in Louisiana to do over the next couple of days. Well the main thing there's there's areas were growing public focused on their role in this situation it's do we talk readings or squad. He bought in the end we talk about everything from crude walker to option medication to a lot of other. What the public needs to understand with this particular. As a clash for abnormal numbers shorten the start of their. If emergency sheltering is needed it's it's not seeing them massive shelter. Efforts may be when you have a Contra flow situation other than score. This may be just giving somebody out of the neighborhood that's certainly good wonder what that reason. And then getting them to police the city so they may need some resources to take with them to show because it could be. Dear to him in some cases depending on what the weather's like. For a lot of resources get to those people so we you know sort of talks about the first 72 zone you. So we growing need people to take that approach when their when their chicken look at their. The second situations the world conditions because most of our penalties from the start them as people were drug. On for the world of barricades mean I'll always be be available. If it's a massive flow. And so watcher were captured two welts wisely you know take a look at 511 LE or YouTube where. And picture you know what you get in June and the final thing she has maintained awareness wasn't cheap media listen to the National Weather Service. Listen to your local officials and make sure you keep that information. In any available in anything be done about the low IQ individuals or drive a fast as the water. I wish picker advocate you know being in living bears out what questions they saw on support to more people laugh. Hurt baucus troubled situations that were born all groups in Rhode while. I Mikey say that it gives you the website is so 511 dot Louisiana dot org. Yes and got a series of sorrow sorrow. We also have been activated our emergency dot LA go web site. Emergency doubt Ellie don't go that kind of a central. Well point people who give to all the media eager to begin or it's some of the state agencies involved in the process. In one other thing his ball and here Louisiana. Got Doug go that's another sore if your beat these groups or anyone else won't get the ball. In helping with the volunteer. Element show on the city's a couple of times or during the showed moderate thanks for your time. You. Might see a communications director for the governor's office of homeland security and emergency preparedness. As web sites are on an emergency. Dot LA dot gov. Volunteer. LA dot gov or let's see how high the water is now. Ties behind Obama now and I like you know I see those scenes stuff from Houston and I think I feel the same way you do it's just it's gut wrenching. And so heartbreaking to seize a fan please send kids into pets. It's heartbreaking to think what they're going through because so and so many of you know exactly. How they feel because of what we have been through from the West Bank showing your on WW or good afternoon. To be shown. It. Is an important on. Right out there and you use it to. Be right. There. I. Right in front of City Hall their clogged. I. You're out and out. Yeah I know exactly where you're talking about. It right right. That. You. About it and didn't. It is you know. We. Eat. Yeah I'm sure there's a shot I appreciate the information look I don't doubt that there's a lot of work being done. But the problem is is politicians just hung out and act like politicians. Instead of serving the people. And that's the main reason we're in the situation room. But heavy rain is heavy rain. But it's gonna always be worse. If people who were in. The government do not do their job. And do not demand that those underneath him due to air jobs. It's a simple. And Larry we could even get into how all. People who work for the government are not as afraid of being fired juvenile hour. And maybe that's one of the reasons why some people. Who worked for the government here and around the country. Don't do as good as job as they could competence is not always encouraged. In a bureaucracy. Tennis and saying I'm getting text here Doctor King boulevard fluttered heading toward the east. So Vern and whoever set to so Vern and I guess it was causeway support osu burning and west esplanade. Is a flooded and I'm getting by text about a number of C canals. And I Jefferson Parish are very very high so hopefully the water stays down again we've got a break in the rain downtown but there's a lot of rain in this area. And this is generally associated with a tropical storm Harvey if you wanna join us from the comet are numbers 260. When he Saturday. Text Amber's age 7871. Thing really describes what we've seen Houston. OMG. We'll be back a definite URL. Well you can look for higher ground for your car because due to the heavy rain the city of New Orleans says it is now illegal to park on a neutral ground. And the sidewalk. However you know there are some. Evildoers. Who would try and sometimes steal cars. If you see anybody mess in our car. Please call nine went on to New Orleans Tom you're under the W well. You know we're just giving you called to note I just tried going down now boulevard or where they are a notepad and it's not passable with a cough. Because well. So but came down Marconi unit still clear although city park is starting to hold a future models wore so when we get the rain and market's gonna come over. And it's not a number I appreciate that very much. So you know we're have a couple of days has this effected the chance of rain tomorrow is even greater than the chance of rain today. Have a chance of rain. Wednesday. Is as good as chance of rain tomorrow which again both Lucy's benefited the Denny gets better toward the weekend. The question is how much are we get. Because we can't take very much. A flash flood watch is in effect for the entire. New Orleans and south Louisiana area. Until Thursday. And the saints play Thursday night. So what's gonna happen this year and the again so. So much going on so much to talk about they will do the best we can't hear WW don't always bring you up to date on the weather. The news and the traffic. If you wanna join us with comic this afternoon you know the number it's 2601. A seventy. Every coach 5042601878. Tex ember is 87870. Here's a Texas says so water gushing out of several drains along Hammond highway between four or delete. And pudge tree boulevard gushing water pushing manhole covers off and filling the streets. You think about how heavy those manhole covers are and Mandel water Jewish hurl stem often the air is just. Unbelievable and a reminder how dangerous and how powerful water can be I'm Scrooge and are coming back.

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Flash Flooding Begins - WWL First News

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Stem Cell Conferences | Cell and Stem Cell Congress | Stem …

Posted: August 26, 2016 at 1:46 pm

On behalf of the organizing committee, it is my distinct pleasure to invite you to attend the Stem Cell Congress-2017. After the success of the Cell Science-2011, 2012, 2013, 2014, 2015, Conference series.LLC is proud to announce the 6th World Congress and expo on Cell & Stem Cell Research (Stem Cell Congress-2017) which is going to be held during March 20-22, 2017, Orlando, Florida, USA. The theme of Stem Cell Congress-2017 is Explore and Exploit the Novel Techniques in Cell and Stem Cell Research.

This annual Cell Science conference brings together domain experts, researchers, clinicians, industry representatives, postdoctoral fellows and students from around the world, providing them with the opportunity to report, share, and discuss scientific questions, achievements, and challenges in the field.

Examples of the diverse cell science and stem cell topics that will be covered in this comprehensive conference include Cell differentiation and development, Cell metabolism, Tissue engineering and regenerative medicine, Stem cell therapy, Cell and gene therapy, Novel stem cell technologies, Stem cell and cancer biology, Stem cell treatment, Tendency in cell biology of aging and Apoptosis and cancer disease, Drugs and clinical developments. The meeting will focus on basic cell mechanism studies, clinical research advances, and recent breakthroughs in cell and stem cell research. With the support of many emerging technologies, dramatic progress has been made in these areas. In Stem Cell Congress-2017, you will be able to share experiences and research results, discuss challenges encountered and solutions adopted and have opportunities to establish productive new academic and industry research collaborations.

In association with the Stem Cell Congress-2017 conference, we will invite those selected to present at the meeting to publish a manuscript from their talk in the journal Cell Science with a significantly discounted publication charge. Please join us in Philadelphia for an exciting all-encompassing annual Stem Cell get together with the theme of better understanding from basic cell mechanisms to latest Stem Cell breakthroughs!

Haval Shirwan, Ph.D. Executive Editor, Journal of Clinical & Cellular Immunology Dr. Michael and Joan Hamilton Endowed Chair in Autoimmune Disease Professor, Department of Microbiology and Immunology Director, Molecular Immunomodulation Program, Institute for Cellular Therapeutics, University of Louisville, Louisville, KY

Track01:Stem Cells

The most well-established and widely used stem cell treatment is thetransplantationof blood stem cells to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers. Since the 1970s,skin stem cellshave been used to grow skin grafts for patients with severe burns on very large areas of the body. Only a few clinical centers are able to carry out this treatment and it is usually reserved for patients with life-threatening burns. It is also not a perfect solution: the new skin has no hair follicles or sweat glands. Research aimed at improving the technique is ongoing.

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7thAnnual Conference on Stem Cell and Regenerative MedicineAug 4-5, 2016, Manchester, UK;2nd InternationalConference on AntibodiesJuly 14-15, 2016 Philadelphia, USA; 2nd InternationalConference on Innate ImmunityJuly 21-22, 2016 Berlin, Germany; 2ndInternational Congress on Neuroimmunology March 31-April 02, 2016 Atlanta, USA; InternationalConference on Cancer Immunology July 28-30, 2016 Melbourne, Australia; 5th InternationalConference on ImmunologyOctober 24-26, 2016 Chicago, USA;Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, Mar 610 2016, Whistler, Canada;Systems Immunology: From Molecular Networks to Human Biology, Jan 1014 2016, Big Sky, USA;Novel Immunotherapeutics Summit, Jan 2526 2016, San Diego, USA;Stromal Cells in Immunity, Feb 711 2016, Keystone, USA; 26th European Congress ofClinical Microbiology, April 912 2016, Istanbul, Turkey

Track 02: Stem Cell Banking:

Stem Cell Banking is a facility that preserves stem cells derived from amniotic fluid for future use. Stem cell samples in private or family banks are preserved precisely for use by the individual person from whom such cells have been collected and the banking costs are paid by such person. The sample can later be retrieved only by that individual and for the use by such individual or, in many cases, by his or her first-degree blood relatives.

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8thWorld Congress on Stem Cell ResearchMarch 20-22, 2017 Orlando, USAInternationalConference on Cancer ImmunologyJuly 28-30, 2016 Melbourne, Australia; 5th InternationalConference on ImmunologyOctober 24-26, 2016 Chicago, USA;Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, Mar 610 2016, Whistler, Canada;Systems Immunology: From Molecular Networks to Human Biology, Jan 1014 2016, Big Sky, USA;Novel Immunotherapeutics Summit, Jan 2526 2016, San Diego, USA;Stromal Cells in Immunity, Feb 711 2016, Keystone, USA; 26th European Congress ofClinical Microbiology, April 912 2016, Istanbul, Turkey

Track 03: Stem Cell Therapy:

Autologous cells are obtained from one's own body, just as one may bank his or her own blood for elective surgical procedures. Adult stem cells are frequently used in medical therapies, for example in bone marrow transplantation. Human embryonic stem cells may be grown in vivo and stimulated to produce pancreatic -cells and later transplanted to the patient. Its success depends on response of the patients immune system and ability of the transplanted cells to proliferate, differentiate and integrate with the target tissue.

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4th InternationalConference on Plant GenomicsJuly 14-15, 2016 Brisbane, Australia; 8thWorld Congress on Stem Cell ResearchMarch 20-22, 2017 Orlando, USA; 7thAnnual Conference on Stem Cell and Regenerative MedicineAug 4-5, 2016, Manchester, UK; 2nd InternationalConference on Tissue preservation and BiobankingSeptember 12-13, 2016 Philadelphia, USA, USA;World Congress on Human GeneticsOctober 31- November 02, 2016 Valencia, Spain; 12thEuro Biotechnology CongressNovember 7-9, 2016 Alicante, Spain; 2nd InternationalConference on Germplasm of Ornamentals, Aug 8-12, 2016, Atlanta, USA; 7th Internationalconference on Crop Science, Aug 1419 2016, Beijing, China;Plant Epigenetics: From Genotype to Phenotype, Feb 1519 2016, Taos, USA;Germline Stem Cells Conference, June 1921 2016, San Francisco, USA;Conference on Water Stressin Plants, 29 May 3 June 2016, Ormont-Dessus, Switzerland

Track 04: Novel Stem Cell Technologies:

Stem cell technology is a rapidly developing field that combines the efforts of cell biologists, geneticists, and clinicians and offers hope of effective treatment for a variety of malignant and non-malignant diseases. Stem cells are defined as totipotent progenitor cells capable of self-renewal and multilineage differentiation. Stem cells survive well and show stable division in culture, making them ideal targets for in vitro manipulation. Although early research has focused on haematopoietic stem cells, stem cells have also been recognised in other sites. Research into solid tissue stem cells has not made the same progress as that on haematopoietic stem cells.

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InternationalConference on Next Generation SequencingJuly 21-22, 2016 Berlin, Germany; 5th InternationalConference on Computational Systems BiologyAugust 22-23, 2016 Philadelphia, USA; 7th InternationalConference on BioinformaticsOctober 27-28, 2016 Chicago, USA; InternationalConference on Synthetic BiologySeptember 28-30, 2015 Houston, USA; 4th InternationalConference on Integrative BiologyJuly 18-20, 2016 Berlin, Germany; 1st InternationalConference on Pharmaceutical BioinformaticsJan 2426 2016, Pattaya, Thailand; EMBL Conference: TheEpitranscriptome, Apr 2022 2016, Heidelberg, Germany; 2016Whole-Cell ModelingSummer School, Apr 38 2016, Barcelona, Spain; 3rd InternationalMolecular Pathological Epidemiology, May 1213 2016, Boston, USA; 5thDrug FormulationSummit, Jan 2527 2016, Philadelphia, USA

Track 05: Stem Cell Treatment:

Bone marrow transplant is the most extensively used stem-cell treatment, but some treatment derived from umbilical cord blood are also in use. Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions, diabetes, heart disease, and other conditions.

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7th InternationalConference on BioinformaticsOctober 27-28, 2016 Chicago, USA; InternationalConference on Synthetic BiologySeptember 28-30, 2015 Houston, USA; 7thAnnual Conference on Stem Cell and Regenerative MedicineAug 4-5, 2016, Manchester, UK; 4th InternationalConference on Integrative BiologyJuly 18-20, 2016 Berlin, Germany; 1st InternationalConference on Pharmaceutical BioinformaticsJan 2426 2016, Pattaya, Thailand; EMBL Conference: TheEpitranscriptome, Apr 2022 2016, Heidelberg, Germany; 2016Whole-Cell ModelingSummer School, Apr 38 2016, Barcelona, Spain; 3rd InternationalMolecular Pathological Epidemiology, May 1213 2016, Boston, USA; 5thDrug FormulationSummit, Jan 2527 2016, Philadelphia, USA

Track 06: Stem cell apoptosis and signal transduction:

Apoptosis is the process of programmed cell death (PCD) that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Most cytotoxic anticancer agents induce apoptosis, raising the intriguing possibility that defects in apoptotic programs contribute to treatment failure. Because the same mutations that suppress apoptosis during tumor development also reduce treatment sensitivity, apoptosis provides a conceptual framework to link cancer genetics with cancer therapy.

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InternationalConference on Restorative MedicineOctober 24-26, 2016 Chicago, USA;; 3rdWorld Congress onHepatitis and Liver Diseases October 17-19, 2016 Dubai, UAE; InternationalConference on Molecular BiologyOctober 13-15, 2016 Dubai, UAE; 2nd InternationalConference on Tissue preservation and Biobanking September12-13, 2016 Philadelphia USA; 26thEuropean Congress ofClinical Microbiology, April 912 2016, Istanbul, Turkey;Conference onCell Growth and Regeneration, Jan 1014 2016, Breckenridge, USA ;

Track 07: Stem Cell Biomarkers:

Molecular biomarkers serve as valuable tools to classify and isolate embryonic stem cells (ESCs) and to monitor their differentiation state by antibody-based techniques. ESCs can give rise to any adult cell type and thus offer enormous potential for regenerative medicine and drug discovery. A number of biomarkers, such as certain cell surface antigens, are used to assign pluripotent ESCs; however, accumulating evidence suggests that ESCs are heterogeneous in morphology, phenotype and function, thereby classified into subpopulations characterized by multiple sets of molecular biomarkers.

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8thWorld Congress on Stem Cell ResearchMarch 20-22, 2017 Orlando, USA; 5th International Conference onCell and Gene TherapyMay 19-21, 2016 San Antonio, USA; 7thAnnual Conference on Stem Cell and Regenerative MedicineAug 4-5, 2016, Manchester, UK; InternationalConference on Restorative MedicineOctober 24-26, 2016 Chicago, USA; InternationalConference on Molecular BiologyOctober 13-15, 2016 Dubai, UAE; 2nd InternationalConference on Tissue preservation and Biobanking September12-13, 2016 Philadelphia USA;Conference on Cardiac Development, Regeneration and RepairApril 3 7, 2016 Snowbird, Utah, USA; Stem Cell DevelopmentMay 22-26, 2016 Hillerd, Denmark; Conference onHematopoietic Stem Cells, June 3-5, 2016 Heidelberg, Germany; ISSCR Pluripotency - March 22-24, 2016 Kyoto, Japan

Track 08: Cellular therapies:

Cellular therapy also called Cell therapy is therapy in which cellular material is injected into a patient, this generally means intact, living cells. For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy.

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InternationalConference on Genetic Counseling and Genomic MedicineAugust 11-12, 2016 Birmingham, UK;World Congress on Human GeneticsOctober 31- November 02, 2016 Valencia, Spain; InternationalConference on Molecular BiologyOctober 13-15, 2016 Dubai, UAE; 3rd InternationalConference on Genomics & PharmacogenomicsSeptember 21-23, 2015 San Antonio, USA; EuropeanConference on Genomics and Personalized MedicineApril 25-27, 2016 Valencia, Spain;Genomics and Personalized Medicine, Feb 711 2016, Banff, Canada; Drug Discovery for Parasitic Diseases, Jan 2428 2016, Tahoe City, USA; Heart Failure: Genetics,Genomics and Epigenetics, April 37 2016, Snowbird, USA; Understanding the Function ofHuman Genome Variation, May 31 June 4 2016, Uppsala, Sweden; 5thDrug Formulation SummitJan2527,2016,Philadelphia, USA

Track 09: Stem cells and cancer:

Cancer can be defined as a disease in which a group of abnormal cells grow uncontrollably by disregarding the normal rules of cell division. Normal cells are constantly subject to signals that dictate whether the cells should divide, differentiate into another cell or die. Cancer cells develop a degree of anatomy from these signals, resulting in uncontrolled growth and proliferation. If this proliferation is allowed to continue and spread, it can be fatal.

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2ndWorld Congress on Applied MicrobiologyOctober 31-November 02, 2016 Istanbul, Turkey; InternationalConference on Infectious Diseases & Diagnostic MicrobiologyOct 3-5, 2016 Vancouver, Canada;18th International conference on Neuroscience, April 26 2016, Sweden, Austria; 6th Annual Traumatic Brain Injury Conference, May 1112 2016, Washington, D.C., USA; Common Mechanisms of Neurodegeneration, June 1216 2016, Keystone, USA; Neurology Caribbean Cruise, Aug 2128 2016, Fort Lauderdale, USA; Annual Meeting of the German Society ofNeurosurgery(DGNC), June 1215 2016, Frankfurt am Main, Germany

Track 10: Embryonic stem cells:

Embryonic stem cells have a major potential for studying early steps of development and for use in cell therapy. In many situations, however, it will be necessary to genetically engineer these cells. A novel generation of lentivectors which permit easy genetic engineering of mouse and human embryonic stem cells.

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4thCongress on Bacteriology and Infectious DiseasesMay 16-18, 2016 San Antonio, USA; 2ndWorld Congress on Applied MicrobiologyOctober 31-November 02, 2016 Istanbul, Turkey; InternationalConference on Infectious Diseases & Diagnostic MicrobiologyOct 3-5, 2016 Vancouver, Canada; InternationalConference on Water MicrobiologyJuly 18-20, 2016 Chicago, USA; 5th InternationalConference on Clinical MicrobiologyOctober 24-26, 2016 Rome, Italy; Axons: FromCell Biologyto Pathology Conference, 2427 January 2016, Santa Fe, USA; 26th EuropeanCongress of Clinical MicrobiologyApril 912 2016, Istanbul, Turkey;Conference on Gut Microbiota, Metabolic Disorders and Beyond, April 1721 2016, Newport, USA; 7th EuropeanSpores Conference, April 1820 2016, Egham, UK; New Approaches to Vaccines forHuman and Veterinary Tropical Diseases, May 2226 2016, Cape Town, South Africa

Track 11: Cell differentiation and disease modeling:

Cellular differentiation is the progression, whereas a cell changes from one cell type to another. Variation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiationalmost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.

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4thCongress on Bacteriology and Infectious DiseasesMay 16-18, 2016 San Antonio, USA; 2ndWorld Congress on Applied MicrobiologyOctober 31-November 02, 2016 Istanbul, Turkey; InternationalConference on Infectious Diseases & Diagnostic MicrobiologyOct 3-5, 2016 Vancouver, Canada; InternationalConference on Water MicrobiologyJuly 18-20, 2016 Chicago, USA; 5thInternationalConference on Clinical MicrobiologyOctober 24-26, 2016 Rome, Italy; Axons: FromCell Biologyto Pathology Conference, 2427 January 2016, Santa Fe, USA; 26thEuropeanCongress of Clinical MicrobiologyApril 912 2016, Istanbul, Turkey;Conference on Gut Microbiota, Metabolic Disorders and Beyond, April 1721 2016, Newport, USA; 7thEuropeanSpores Conference, April 1820 2016, Egham, UK; New Approaches toVaccines forHuman and Veterinary Tropical Diseases, May 2226 2016, Cape Town, South Africa

Track 12: Tissue engineering:

Tissue Engineering is the study of the growth of new connective tissues, or organs, from cells and a collagenous scaffold to produce a fully functional organ for implantation back into the donor host. Powerful developments in the multidisciplinary field of tissue engineering have produced a novel set of tissue replacement parts and implementation approaches. Scientific advances in biomaterials, stem cells, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabricate tissues in the laboratory from combinations of engineered extracellular matrices cells, and biologically active molecules.

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4thCongress on Bacteriology and Infectious DiseasesMay 16-18, 2016 San Antonio, USA; 2ndWorld Congress on Applied MicrobiologyOctober 31-November 02, 2016 Istanbul, Turkey; InternationalConference on Infectious Diseases & Diagnostic MicrobiologyOct 3-5, 2016 Vancouver, Canada; InternationalConference on Water MicrobiologyJuly 18-20, 2016 Chicago, USA; 5thInternationalConference on Clinical MicrobiologyOctober 24-26, 2016 Rome, Italy; Axons: FromCell Biologyto Pathology Conference, 2427 January 2016, Santa Fe, USA; 26thEuropeanCongress of Clinical MicrobiologyApril 912 2016, Istanbul, Turkey;Conference on Gut Microbiota, Metabolic Disorders and Beyond, April 1721 2016, Newport, USA; 7thEuropeanSpores Conference, April 1820 2016, Egham, UK; New Approaches toVaccines forHuman and Veterinary Tropical Diseases, May 2226 2016, Cape Town, South Africa

Track 13: Stem cell plasticity and reprogramming:

Stem cell plasticity denotes to the potential of stem cells to give rise to cell types, previously considered outside their normal repertoire of differentiation for the location where they are found. Included under this umbrella title is often the process of transdifferentiation the conversion of one differentiated cell type into another, and metaplasia the conversion of one tissue type into another. From the point of view of this entry, some metaplasias have a clinical significance because they predispose individuals to the development of cancer.

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InternationalConference on Case ReportsMarch 31-April 02, 2016 Valencia, Spain; 2nd International Meeting onClinical Case ReportsApril 18-20, 2016 Dubai, UAE; 3rd Experts Meeting onMedical Case ReportsMay 09-11, 2016 New Orleans, Louisiana, USA; 12thEuro BiotechnologyCongress November 7-9, 2016 Alicante, Spain; 2nd International Conference onTissue preservation and BiobankingSeptember 12-13, 2016 Philadelphia, USA; 11thWorld Conference BioethicsOctober 20-22, 2015 Naples, Italy;Annual Conference Health Law and Bioethics, May 6-7 2016 Cambridge, MA, USA; 27th Maclean Conference on Clinical Medical Ethics, Nov 13-14, 2015, Chicago, USA; CFP: Global Forum on Bioethics in Research, Nov 3-4, 2015, Annecy, France

Track 14: Gene therapy and stem cells

Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.

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Track 15: Tumour cell science:

An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant. Tomour usually reflect the kind of tissue they arise in. Treatment is also specific to the location and type of the tumor. Benign tumors can sometimes simply be ignored, cancerous tumors; options include chemotherapy, radiation, and surgery.

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Track 16: Reprogramming stem cells: computational biology

Computational Biology, sometimes referred to as bioinformatics, is the science of using biological data to develop algorithms and relations among various biological systems. Bioinformatics groups use computational methods to explore the molecular mechanisms underpinning stem cells. To accomplish this bioinformaticsdevelop and apply advanced analysis techniques that make it possible to dissect complex collections of data from a wide range of technologies and sources.

Related Stem Cell Conferences|Stem Cell Congress|Cell and Stem Cell Conferences|Conference Series LLC

The fields of stem cell biology and regenerative medicine research are fundamentally about understanding dynamic cellular processes such as development, reprogramming, repair, differentiation and the loss, acquisition or maintenance of pluripotency. In order to precisely decipher these processes at a molecular level, it is critical to identify and study key regulatory genes and transcriptional circuits. Modern high-throughput molecular profiling technologies provide a powerful approach to addressing these questions as they allow the profiling of tens of thousands of gene products in a single experiment. Whereas bioinformatics is used to interpret the information produced by such technologies.

Related Stem Cell Conferences|Stem Cell Congress|Cell and Stem Cell Conferences|Conference Series LLC

8th World Congress on Cell & Stem Cell Research

The success of the 7 Cell Science conferences series has given us the prospect to bring the gathering one more time for our 8thWorld Congress 2017 meet in Orlando, USA. Since its commencement in 2011 cell science series has perceived around 750 researchers of great potentials and outstanding research presentations around the globe. The awareness of stem cells and its application is increasing among the general population that also in parallel offers hope and add woes to the researchers of cell science due to the potential limitations experienced in the real-time.

Stem Cell Research-2017has the goal to fill the prevailing gaps in the transformation of this science of hope to promptly serve solutions to all in the need.World Congress 2017 will have an anticipated participation of 100-120 delegates from around the world to discuss the conference goal.

History of Stem cells Research

Stem cells have an interesting history, in the mid-1800s it was revealed that cells were basically the building blocks of life and that some cells had the ability to produce other cells. Efforts were made to fertilize mammalian eggs outside of the human body and in the early 1900s, it was discovered that some cells had the capacity to generate blood cells. In 1968, the first bone marrow transplant was achieved successfully to treat two siblings with severe combined immunodeficiency. Other significant events in stem cell research include:

1978: Stem cells were discovered in human cord blood 1981: First in vitro stem cell line developed from mice 1988: Embryonic stem cell lines created from a hamster 1995: First embryonic stem cell line derived from a primate 1997: Cloned lamb from stem cells 1997: Leukaemia origin found as haematopoietic stem cell, indicating possible proof of cancer stem cells

Funding in USA:

No federal law forever did embargo stem cell research in the United States, but only placed restrictions on funding and use, under Congress's power to spend. By executive order on March 9, 2009, President Barack Obama removed certain restrictions on federal funding for research involving new lines of humanembryonic stem cells. Prior to President Obama's executive order, federal funding was limited to non-embryonic stem cell research and embryonic stem cell research based uponembryonic stem celllines in existence prior to August 9, 2001. In 2011, a United States District Court "threw out a lawsuit that challenged the use of federal funds for embryonic stem cell research.

Members Associated with Stem Cell Research:

Discussion on Development, Regeneration, and Stem Cell Biology takes an interdisciplinary approach to understanding the fundamental question of how a single cell, the fertilized egg, ultimately produces a complex fully patterned adult organism, as well as the intimately related question of how adult structures regenerate. Stem cells play critical roles both during embryonic development and in later renewal and repair. More than 65 faculties in Philadelphia from both basic science and clinical departments in the Division of Biological Sciences belong to Development, Regeneration, and Stem Cell Biology. Their research uses traditional model species including nematode worms, fruit-flies, Arabidopsis, zebrafish, amphibians, chick and mouse as well as non-traditional model systems such as lampreys and cephalopods. Areas of research focus include stem cell biology, regeneration, developmental genetics, and cellular basis of development, developmental neurobiology, and evo-devo (Evolutionary developmental biology).

Stem Cell Market Value:

Worldwide many companies are developing and marketing specialized cell culture media, cell separation products, instruments and other reagents for life sciences research. We are providing a unique platform for the discussions between academia and business.

Global Tissue Engineering & Cell Therapy Market, By Region, 2009 2018

$Million

Why to attend???

Stem Cell Research-2017 could be an outstanding event that brings along a novel and International mixture of researchers, doctors, leading universities and stem cell analysis establishments creating the conference an ideal platform to share knowledge, adoptive collaborations across trade and world, and assess rising technologies across the world. World-renowned speakers, the most recent techniques, tactics, and the newest updates in cell science fields are assurances of this conference.

A Unique Opportunity for Advertisers and Sponsors at this International event:

http://stemcell.omicsgroup.com/sponsors.php

UAS Major Universities which deals with Stem Cell Research

University of Washington/Hutchinson Cancer Center

Oregon Stem Cell Center

University of California Davis

University of California San Francisco

University of California Berkeley

Stanford University

Mayo Clinic

Major Stem Cell Organization Worldwide:

Norwegian Center for Stem Cell Research

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Stem Cell Conferences | Cell and Stem Cell Congress | Stem ...

Posted in Louisiana Stem Cells | Comments Off on Stem Cell Conferences | Cell and Stem Cell Congress | Stem …

Louisiana (Stem Cell) – what-when-how

Posted: August 23, 2016 at 8:43 pm

The state of Louisiana encourages the biotechnology industry, including adult stem cell research for economic development and scientific innovation. Growth in biotechnology and biomedicine for translating basic research into medical therapies is possible through appropriate legislation and funding, as well as strong collaborative networks for scientific research for industrial, academic, and clinical institutions throughout the state.

The Louisiana Alliance for Biotechnology provides networking opportunities between academic and commercial researchers to encourage economic growth and the transfer of basic research into commercially viable products. The Biomedi-cal Research Foundation of Northwest Louisiana promotes regional scientific growth and development in coordination with Louisiana State University Medical Center in Shreveport.

The foundation operates the Biomedical Research Institute and a Positron Emission Tomography Imaging Center for diagnosis and research in various fields, including immunology, neurological and cardiovascular cellular communication, signal transduction, and neu-rosciences. The foundations clinical application is performed by the Center for Biotechnology Innovation with a focus on research in energy, photonics, biogenetics, orthopedics, and medical informatics. The foundation is also developing a research and technology park called the International Technology Center to focus on biomedical healthcare delivery and biotechnology. This effort brings together nine of the academic institutions in north Louisiana

Louisiana is the only U.S. state to specifically prohibit research on human embryos.

The Louisiana Gene Therapy Research Consortium was established in 2000 with funds given by the state of Louisiana for enhancing economic growth and innovation by attracting researchers, building research laboratories, and producing gene and cell therapies to be used in human clinical trials.

At present, no federal legislation in the United States is in place to regulate stem cell research (except by executive order to not allow federal funding for generation of new embryonic stem cell lines and limiting research on embryonic stem cell lines); this leaves each state responsible for determining policy and funding for stem cell research. Louisiana is the only state to specifically prohibit research on human embryos and restricts human embryonic stem cell research.

For expansion of the biotech industry in Louisiana, the division of economic development has set up three centers within the state, in Baton Rouge, New Orleans, and Davenport, to provide financial assistance with a small business investment company fund, business development services, and wet laboratory incubator space. Their financial support has allowed the creation of a Good Manufacturing Practice Laboratory for stem cell research and funding for the Louisiana Cancer Research Centers of New Orleans and for the Gene Therapy Research Consortium. They also work with start-up companies to bring to the marketplace the application of research from Louisiana universities.

Pennington Biomedical Research Center at Louisiana State University in Baton Rouge provides research laboratories and inpatient and outpatient medical clinics. The center opened in 1988 with funds provided by a philanthropic gift from C. B. Doc Pennington in 1980. The center is home to eight basic research laboratories, three clinical research units, 19 core service laboratories, and conference space.

The centers researchers specialize in a variety of disciplines including molecular biology, genom-ics and proteomics, and biochemistry. Though dedicated to nutrition and its related health issues, the centers research foci include tissue and organ regeneration postinjury/damage, characterization and biological mechanisms including formation of adult stem cells and adipose tissue, and the epigen-etic basis for human diseases of obesity, hypertension, and adult-onset diabetes.

Tulane University, in addition to providing education, is also a research university with active studies in biotechnology including vaccine and drug development, pain-control therapies, and gene therapy. Basic research is translated into clinical therapy and commercial products by the Office of Technology Development. In 2000 the university formed the Tulane Center for Gene Therapy with the goal of developing therapeutic treatment for a variety of human diseases, using adult stem cells through autologous donation and then turning them into therapy for osteoporosis, osteoarthritis, Parkinsons disease, spinal cord injury, stroke, and Alzheimers disease. The center also provides career development and community education, encouraging dialogue on social, legal, and ethical issues related to gene therapy. Funding for the center is provided through grant funding from national, state, and private sources, including the National Institutes of Health, the Louisiana Gene Therapy Research Consortium, Tulane University Health Sciences Center, Healthcare Company, and private foundations.

In addition to research, the center is a stem cell provider of human adult stem cells, rat stem cells, and mouse stem cells for researchers internationally, with a signed Tulane University Materials Transfer Agreement and handling fee. The center isolates, expands, and characterizes the stem cells in the laboratory and provides protocols for expansion as well as information on the cells.

The Louisiana State University is a public institution of higher learning, with majors in the physical sciences and with schools of medicine in New Orleans and Shreveport. The main campus of the university system is located in Baton Rouge, with campuses throughout the state. Research on stem cells includes survival of stem cells after freezing and their capability to proliferate and differentiate, developing technology in engineering stem cells in sheets or three-dimensional structures for transplant, and working with the Pennington Center to develop protocols for the cryopreser-vation of human adipose adult stem cells. Clinical research through the Gene Therapy Program at the Health Sciences Center at the School of Medicine in New Orleans includes translating the basic science of genetic involvement in disease into clinical therapy to prevent or treat some cancers or to restore function to diseased tissues or organs.

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Stem Cell Assays – Promoting Rigorous Reproducible …

Posted: October 19, 2015 at 5:47 pm

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Erectile function restored with stem cells | New Scientist

Posted: October 6, 2015 at 6:51 am

Damage to parts of the penis vital for proper erections has been repaired for the first time with the help of stem cells. In rats, the treatment restored full erections, improved blood flow and accelerated healing.

Ultimately, the researchers hope to treat the 3 to 9 per cent of men who have Peyronies disease, which damages the membrane surrounding the chambers within the penis that swell with blood during arousal. This makes it difficult to achieve a straight erection.

Wayne Hellstrom of Tulane University in New Orleans, Louisiana, and colleagues, extracted stem cells from fat and placed them onto layers of tissue taken from the lining of pig intestine. This material, called small intestinal submucosa (SIS), is already used to replace damaged membrane in men with Peyronies disease, but Hellstrom wanted to see whether adding stem cells would improve healing.

Two months after therapy, tissue analysis showed less scarring and higher levels of regenerative agents such as fibroblast growth factor which accelerate healing in rats treated with SIS plus stem cells compared with those treated with SIS alone. The stem cells induced factors that enhanced blood supply, tissue restoration and erectile function, says Hellstrom.

Production of enzymes that make a blood vessel relaxant vital for erections was also higher in rats given the stem cells. Hellstrom hopes to be able to offer a similar treatment to men.

The apparent mechanisms of action are consistent with other clinical studies showing that fat-derived stem cells are particularly good at improving blood supply and reducing scarring, says Marc Hedrick of regenerative medicine firm Cytori in San Diego, California.

Read more: Stem cells turn into breast implants

Journal reference: Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.1113810109

By Andy Coghlan

Magazine issue 2849 published 28 January 2012

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The Miami Stem Cell Treatment Center Announces an Adult …

Posted: August 1, 2015 at 3:49 pm

Upcoming Adult Stem Cell Lecture on Thursday, August 6, 2015, in Orlando at 4:00 pm

Orlando, Florida (PRWEB) July 30, 2015

The Miami Stem Cell Treatment Center announces a free public seminar on the use of adult stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief, and Dr. Nia Smyrniotis, Medical Director.

The seminar will be held on Thursday, August 6, 2015, at 4:00 pm at our Orlando office, 100 North Dean Road, 2nd Floor, Orlando, FL 32825. Please RSVP at (561) 331-2999, all events are by reservation only.

The Miami Stem Cell Treatment Center (Miami; Boca Raton; Orlando; The Villages; Sarasota, Florida), along with sister affiliates, the Irvine Stem Cell Treatment Center (Irvine; Westlake Village; Sacramento, California) and the Manhattan Regenerative Medicine Medical Group (Manhattan, New York), abide by approved investigational protocols using adult adipose derived stem cells (ADSCs) which can be deployed to improve patients quality of life for a number of chronic, degenerative and inflammatory conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (found within a cellular mixture called stromal vascular fraction (SVF)). ADSCs are exceptionally abundant in adipose tissue. The adipose tissue is obtained from the patient during a 15 minute mini-liposuction performed under local anesthesia in the doctors office. SVF is a protein-rich solution containing mononuclear cell lines (predominantly adult autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important Growth Factors that facilitate the stem cell process and promote their activity.

ADSCs are the bodys natural healing cells - they are recruited by chemical signals emitted by damaged tissues to repair and regenerate the bodys injured cells. The Miami Stem Cell Treatment Center only uses Adult Autologous Stem Cells from a persons own fat No embryonic stem cells are used; and No bone marrow stem cells are used. Current areas of study include: Emphysema, COPD, Asthma, Heart Failure, Heart Attack, Parkinsons Disease, Stroke, Traumatic Brain Injury, Lou Gehrigs Disease, Multiple Sclerosis, Lupus, Rheumatoid Arthritis, Crohns Disease, Muscular Dystrophy, Inflammatory Myopathies, and degenerative orthopedic joint conditions (Knee, Shoulder, Hip, Spine). For more information, or if someone thinks they may be a candidate for one of the adult stem cell protocols offered by the Miami Stem Cell Treatment Center, they may contact Dr. Gionis or Dr. Smyrniotis directly at (561) 331-2999, or see a complete list of the Centers study areas at: MiamiStemCellsUSA.com.

Also, you can listen and call into our radio show, The Stem Cell Show, hosted by Dr. Gionis worldwide on KABC.com ("Listen Live" at 7pm EST) or the KABC app available on the App Store or Google Play.

About the Miami Stem Cell Treatment Center: The Miami Stem Cell Treatment Center, along with sister affiliates, the Irvine Stem Cell Treatment Center and the Manhattan Regenerative Medicine Medical Group, is an affiliate of the California Stem Cell Treatment Center / Cell Surgical Network (CSN); we are located in Miami, Boca Raton, Orlando, The Villages, and Sarasota, Florida. We provide care for people suffering from diseases that may be alleviated by access to adult stem cell based regenerative treatment. We utilize a fat transfer surgical technology to isolate and implant the patients own stem cells from a small quantity of fat harvested by a mini-liposuction on the same day. The investigational protocols utilized by the Miami Stem Cell Treatment Center have been reviewed and approved by an IRB (Institutional Review Board) which is registered with the U.S. Department of Health, Office of Human Research Protection (OHRP); and our studies are registered with Clinicaltrials.gov, a service of the U.S. National Institutes of Health (NIH). For more information, visit our websites: MiamiStemCellsUSA.com, IrvineStemCellsUSA.com, NYStemCellsUSA.com, or TheStemCellShow.com.

For the original version on PRWeb visit: http://www.prweb.com/releases/2015/07/prweb12861292.htm

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Stem Cell Banking Market in India 2015-2019 – KPLC 7 News …

Posted: June 13, 2015 at 1:48 am

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NEW YORK, June 9, 2015 /PRNewswire/ -- About Stem Cell Banking Stem cells are the building blocks of the human body. They originate in the earliest stage of human development and can be found in the various stages of growth from birth till adulthood. When these undifferentiated biological cells divide, they can differentiate into specialized cells. A stem cell bank is a facility that stores stem cells for future use. Stem cell banking, one of the most promising markets in the field of life sciences, is the process of preserving stem cells at temperatures much below the freezing point. This technique is termed as cryopreservation. These cells can be used in the treatment of Parkinson's disease, diabetes, cancer, heart diseases, and others. Technavio's analysts forecast the stem cell banking market in India to grow at a CAGR of 37.85% over the period 2014-2019.

Covered in this Report This report covers the present scenario and the growth prospects of the stem cell banking market in India for the period 2015-2019. To calculate the market size, the report considers revenue generated by stem cell banking service providers. It presents the vendor landscape and corresponding detailed analysis of the top six vendors in the market. The report provides the segmentation of the market based on type of products, applications, and type of banks. Technavio's report, Stem Cell Banking Market in India 2015-2019, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects in the coming years.

Key Vendors - CordLife Sciences India - Cryobanks International India - LifeCell International - Reliance Life Sciences - Stempeutics Research - Tran-Scell Biologics

Other Prominent Vendors - CordCare - Cryo Save India - Cryo Stemcell - International Stem Cell - Jeevan Blood Bank Research Centre - NovaCord - Reelabs - RMS Regrow - Stemade Biotech - StemCyte India Therapeutics - StemOne Biologicals - StemRx BioScience Solutions Key

Market Driver - Growing Potential for Umbilical Cord Cell Banks - For a full, detailed list, view our report Key

Market Challenge - Lack of Awareness - For a full, detailed list, view our report Key

Market Trend - Introduction of New Marketing Concepts - For a full, detailed list, view our report

Key Questions Answered in this Report - What will the market size be in 2019 and what will the growth rate be? - What are the key market trends? - What is driving this market? - What are the challenges to market growth? - Who are the key vendors in this market space? - What are the market opportunities and threats faced by the key vendors? - What are the strengths and weaknesses of the key vendors?

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Adimarket Named Latin American Distributor for Bioquark …

Posted: June 4, 2015 at 10:45 pm

Adimarket, a Global Stem Cells Group subsidiary, has been named distributor in Latin America for Bioquark Biologic regenerative medicine products, developed for tissue and organ repair and regeneration.

MIAMI (PRWEB) June 02, 2015

Global Stem Cells Group subsidiary Adimarket has been named the Latin America distributor for Bioquark, Inc.s biologic products for the regeneration and repair of human organs and tissues. The announcement is the latest in Global Stem Cells Groups ambitious expansion plans in Latin America, a commitment made to meet the regions growing demand for access to regenerative medicine and stem cell therapies.

Bioquark Inc. is focused on the development of biologics that have the ability to alter the regulatory state of human tissues and organs, with the goal of curing a range of chronic diseases, as well as affecting complex tissue regeneration. The biologic regulatory states of human cells, tissues and organs represent the central control processes behind disease, degeneration and aging.

Bioquarks core program focuses on developing a singular class of substances, termed combinatorial biologics, which take a different approach to reversing underlying disease, degeneration or aging processes, as opposed to only effecting only the symptoms of these conditions.

Combinatorial biologics work at the level of the regulatory genome and are modeled off of biochemical dynamics found in various species that can naturally modify biologic regulatory states to achieve beneficial outcomes, such as complex tissue and organ regeneration, disease reversion, and even biological age reversal.

The revolutionary work that Bioquark is performing is a perfect fit for Global Stem Cells Groups vision of the potential that stem cell therapies hold, now and in the future, says Ricardo DeCubas, Global Stem Cells Group co-founder and Regenestem CEO.

The collaboration between Global Stem Cells Group, Adimarket and Bioquark is another step toward GSCGs commitment to expanding its presence in communities that need and deserve access to cutting-edge regenerative medicine, not only in Latin America but also worldwide.

For more information visit the Global Stem Cells Group website, email bnovas@stemcellsgroup.com, or call 305-224-1858.

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