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Category Archives: Regenerative Medicine
Active phase III or II/III cell therapy trials
Posted: December 11, 2011 at 5:05 pm
I know that the moment I publish anything that purports to be comprehensive there will be errors and omissions. At the very least it will almost imminently be out-of-date in a fast-moving sector like cell therapy.
Nonetheless, because there is no other reliable repository of this information, I am daring to put this out there and hope you will feel obligated to assist me in ensuring its accuracy rather than critical of the effort.
What follows is what I currently believe to an current and relatively comprehensive list of phase III or II/III cell therapy trials around the world. I am more confident of the industry list than the academic one. More confident of its completeness and accuracy for North American and Europe than of Asia (particularly China).
There is a spreadsheet behind this that includes more data fields like therapeutic category, cell/tissue source, cell type, expansion, indication, expected completion date, clinical trial site locations, etc. If you want a copy of it, just email me (I'm not hard to find) or comment below.
INDUSTRY PHASE III or II/III (active or expected to be active in 1H 2012)
Aastrom Ixmyelocel-T
Baxter ACT34-CMI
Bioheart Myocell
Cardio3 Biosciences C-CURE
Cardio3 Biosciences C-CURE
Cell Medica adoptive cellular therapy
Cook Myosite AMDC
Cytori ADRCs
GamidaCell - Teva StemEx
Genzyme MACI
Harvest Technologies SmartPReP 2 BMAC
Innovaell IES13 (Urocell?)
Kiaidis Pharma ATIR
Miltenyi CliniMACS CD34 Selection System
Medipost Cartistem
MolMed TK
Newlink Genetics HyperAcute Pancreas
NovaRx Lucanix
Osiris Prochymal
Osiris Prochymal
Pervasis Vasugel
The 21 active or imminently active cell therapy industry-sponsored trials listed above break down as follows:
- 52% (12) are autologous
- 33% (7) are allogeneic
- Two are gene-modified allogeneic
- One involves autologous and allogeneic cells
- 24% (5) are for cardiac-related indications
- 33% (7) are for oncology or related indications
- Two are for cartilage repair
* ACADEMIC PHASE III or II/III
- Assistance Publique - Hôpitaux de Paris (France)
- Association of Dutch Burn Centres (Netherlands)
- Barts and The London NHS Trust (UK)
- Erasmus Medical Center (Netherlands)
- European Group for Blood and Marrow Transplantation (Europe)
- Leiden University Medical Center (Netherlands)
- Meshalkin Research Institute of Pathology of Circulation (Russia)
- Meshalkin Research Institute of Pathology of Circulation (Russia)
- Ministry of Health (Malaysia)
- Royan Institute (Iran)
- Rush University Medical Center, University of Sao Paulo, Uppsala University (US, Brazil, Sweden)
- Third Military Medical University (Chia)
- University of Minnesota, Masonic Cancer Center (US)
- University of Minnesota, Masonic Cancer Center (US)
- University Hospital of North Norway (Norway)
- University of Utah (US)
* Active trials only - excludes trials which appear inactive, abandoned, and/or are stem cell transplant in oncology. Primary source is CinicalTrials.gov.
___________________________________
I will try to keep this list updated at least once-per-quarter and indicate the date of the last update at the top of the post.
I eagerly encourage all readers to comment below or email direct with any errors and/or omissions.
Posted in Regenerative Medicine
Comments Off on Active phase III or II/III cell therapy trials
Active phase III or II/III cell therapy trials
Posted: December 11, 2011 at 5:02 pm
I know that the moment I publish anything that purports to be comprehensive there will be errors and omissions. At the very least it will almost imminently be out-of-date in a fast-moving sector like cell therapy.
Nonetheless, because there is no other reliable repository of this information, I am daring to put this out there and hope you will feel obligated to assist me in ensuring its accuracy rather than critical of the effort.
What follows is what I currently believe to an current and relatively comprehensive list of phase III or II/III cell therapy trials around the world. I am more confident of the industry list than the academic one. More confident of its completeness and accuracy for North American and Europe than of Asia (particularly China).
There is a spreadsheet behind this that includes more data fields like therapeutic category, cell/tissue source, cell type, expansion, indication, expected completion date, clinical trial site locations, etc. If you want a copy of it, just email me (I'm not hard to find) or comment below.
INDUSTRY PHASE III or II/III (active or expected to be active in 1H 2012)
Aastrom Ixmyelocel-T
Baxter ACT34-CMI
Bioheart Myocell
Cardio3 Biosciences C-CURE
Cardio3 Biosciences C-CURE
Cell Medica adoptive cellular therapy
Cook Myosite AMDC
Cytori ADRCs
GamidaCell - Teva StemEx
Genzyme MACI
Harvest Technologies SmartPReP 2 BMAC
Innovaell IES13 (Urocell?)
Kiaidis Pharma ATIR
Miltenyi CliniMACS CD34 Selection System
Medipost Cartistem
MolMed TK
Newlink Genetics HyperAcute Pancreas
NovaRx Lucanix
Osiris Prochymal
Osiris Prochymal
Pervasis Vasugel
The 21 active or imminently active cell therapy industry-sponsored trials listed above break down as follows:
- 52% (12) are autologous
- 33% (7) are allogeneic
- Two are gene-modified allogeneic
- One involves autologous and allogeneic cells
- 24% (5) are for cardiac-related indications
- 33% (7) are for oncology or related indications
- Two are for cartilage repair
* ACADEMIC PHASE III or II/III
- Assistance Publique - Hôpitaux de Paris (France)
- Association of Dutch Burn Centres (Netherlands)
- Barts and The London NHS Trust (UK)
- Erasmus Medical Center (Netherlands)
- European Group for Blood and Marrow Transplantation (Europe)
- Leiden University Medical Center (Netherlands)
- Meshalkin Research Institute of Pathology of Circulation (Russia)
- Meshalkin Research Institute of Pathology of Circulation (Russia)
- Ministry of Health (Malaysia)
- Royan Institute (Iran)
- Rush University Medical Center, University of Sao Paulo, Uppsala University (US, Brazil, Sweden)
- Third Military Medical University (Chia)
- University of Minnesota, Masonic Cancer Center (US)
- University of Minnesota, Masonic Cancer Center (US)
- University Hospital of North Norway (Norway)
- University of Utah (US)
* Active trials only - excludes trials which appear inactive, abandoned, and/or are stem cell transplant in oncology. Primary source is CinicalTrials.gov.
___________________________________
I will try to keep this list updated at least once-per-quarter and indicate the date of the last update at the top of the post.
I eagerly encourage all readers to comment below or email direct with any errors and/or omissions.
Posted in Regenerative Medicine
Comments Off on Active phase III or II/III cell therapy trials
StemCellTV Talks to Morrie Ruffin of Alliance for Regenerative Medicine at Meeting on the Mesa – Video
Posted: December 10, 2011 at 11:27 am
William Bruyea, host of StemCellTV talks to Morrie Ruffin, co-founder and managing director of Alliance for Regenerative Medicine at the Meeting on the Mesa partnering forum at Sanford Consortium in La Jolla, CA. Morrie discusses regenerative medicine, stem cells and development.
Original post:
StemCellTV Talks to Morrie Ruffin of Alliance for Regenerative Medicine at Meeting on the Mesa - Video
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StemCellTV Talks to Elona Baum of the California Institute of Regenerative Medicine – Video
Posted: December 10, 2011 at 11:27 am
William Bruyea, host of StemCellTV talks to Elona Baum of the California Institute for Regenerative Medicine (CIRM) about the Meeting on the Mesa Partnering Event at Sanford Consortium and co-sponsoring with Alliance for Regenerative Medicine (ARM).
See the article here:
StemCellTV Talks to Elona Baum of the California Institute of Regenerative Medicine - Video
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StemCellTV Talks to Morrie Ruffin of Alliance for Regenerative Medicine at Meeting on the Mesa – Video
Posted: December 10, 2011 at 10:19 am
William Bruyea, host of StemCellTV talks to Morrie Ruffin, co-founder and managing director of Alliance for Regenerative Medicine at the Meeting on the Mesa partnering forum at Sanford Consortium in La Jolla, CA. Morrie discusses regenerative medicine, stem cells and development.
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StemCellTV Talks to Morrie Ruffin of Alliance for Regenerative Medicine at Meeting on the Mesa - Video
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StemCellTV Talks to Elona Baum of the California Institute of Regenerative Medicine – Video
Posted: December 10, 2011 at 2:23 am
William Bruyea, host of StemCellTV talks to Elona Baum of the California Institute for Regenerative Medicine (CIRM) about the Meeting on the Mesa Partnering Event at Sanford Consortium and co-sponsoring with Alliance for Regenerative Medicine (ARM).
Continue reading here:
StemCellTV Talks to Elona Baum of the California Institute of Regenerative Medicine - Video
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4th International Symposium on Regenerative Medicine, Tissue and Genetic Engineering – Video
Posted: December 8, 2011 at 12:55 pm
TV Avala, private network, morning program, Vuk Devrnja, MD, MSc. describes the upcoming 4th International Symposium on Regenerative Medicine, Tissue and Genetic Engineering, in Belgrade, Serbia. Additionally, explains stem cell application in clinical therapy and possibilities in the future.
Follow this link:
4th International Symposium on Regenerative Medicine, Tissue and Genetic Engineering - Video
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Mayo Clinic Regenerative Medicine Consult Service – Video
Posted: December 3, 2011 at 10:00 am
Learn more about Mayo Clinic's new Regenerative Medicine Consult service from a Mayo Clinic expert on stem cell therapies.
View original post here:
Posted in Regenerative Medicine
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McEwen Centre for Regenerative Medicine – Video
Posted: December 2, 2011 at 3:36 pm
The McEwen Centre for Regenerative Medicine was established at University Health Network in 2003 with a generous donation from Rob and Cheryl McEwen, which they matched in 2006 with a second donation. The McEwen Centres vision is to be a world-renowned centre for stem cell biology and regenerative medicine. To achieve this ambitious goal, the team of McEwen Investigators is working together to accelerate the development of more effective treatments for conditions such as heart disease, diabetes, respiratory disease and spinal cord injury.
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Retroviruses, Reproduction, and Regenerative Medicine: The Influence of Federal Funding – Video
Posted: December 2, 2011 at 3:36 pm
Ann Anderson Kiessling, Ph.D. (Harvard Medical School and the Bedford Stem Cell Research Foundation, Bedford Massachusetts) was introduced by Dorrie Fontaine, Ph.D., RN, FAAN (Sadie Health Cabaniss Professor and Dean, School of Nursing, University of Virginia) who also described a newly established award by the School of Nursing, called the "Alumni Achievement Award," which is awarded to a nursing graduate who has contributed beyond the field of nursing
See the rest here:
Retroviruses, Reproduction, and Regenerative Medicine: The Influence of Federal Funding - Video
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