Category Archives: Regenerative Medicine

Contributed Commentary by Per Hammer, Cytiva

July 15, 2022 | Historically, the heavily regulated biopharma industry has been slow to adopt new technologies. However, a shift toward automation is vital to ensure that next-generation solutionssuch as cell and gene therapiesare produced at scale.

Less than one in five senior pharma executives strongly believe that frontier technologies, such as artificial intelligence, are widely adopted to support automation and increase the speed of specific processes. With cell therapies approved by global regulatory bodies, it is time to accelerate smart technologies and cell and gene therapy manufacturing.

Todays cell therapy treatments are often made on a small-scale, include manual preparation steps, and are produced for a clinical trial setting. Researchers spend days processing cellular material, monitoring its growth during the expansion phase, and preparing for re-administration to the patient. This process is demonstrated in administering autologous treatments so that every patient receives a unique living drug.

Though the current process is complex, it offers inspiring outcomes. For example, on April 1, 2022, the Food and Drug Administration (FDA) approved Kite Pharmas Yescarta, a chimeric antigen receptor (CAR) T-cell therapy for adult patients with large B-cell lymphoma. This kind of cancer is usually resistant to initial treatment and relapses within one year. With FDA approval, Yescarta (axicabtagene ciloleucel) is now the second-line treatment, a first for an autologous CAR T-cell therapy.

Cell Therapy Enters Mainstream

The exceptional results emerging from cell therapy clinical trials suggest we are entering a new phase of medical treatmentone where we can expect far more from our healthcare interventions than we ever imagined. Following the regulatory approval of autologous CAR T-cell therapies, the global cancer treatment landscape is changing, and the future is bright.

The success of COVID-19 vaccines signaled the arrival of the genomic medicines ageone where we hope to see cell and gene therapies deliver long-term remission and even cures for patients with some of the most complex diseases. According to the Alliance for Regenerative Medicine 2021 Annual Report, nearly 60% of the ongoing regenerative medicine clinical trials studied prevalent diseases by the end of the calendar year. But to get these powerful treatments to those who need them, we must have an automated manufacturing infrastructure that can generate cell therapies to meet increased demand in the coming years.

Saving Time Through Automation

Time is of the utmost importance, as biopharma manufacturing involves patient cells that have limited viability. Manual approaches to cell therapy production are time-consuming, and tasks such as checking cells at regular intervals during expansion are laborious. Another time-draining factor is the workflow and cleaning routines involved in maintaining a safe lab environment.

Automated solutions reduce or remove many of these challenges. After setting up a process, an operator can focus on other things while critical parameters such as temperature, pH level, gas transfer, and flow rates are monitored and controlled without human intervention.

Reducing Risks for Better Results

Manual cell processing solutions are complex, with many checkpoints across isolation, expansion, harvesting, and preservation stages. Unfortunately, each of these steps increases the risk potential. Despite the research teams expertise, there is still a chance that materials could be inadvertently contaminated during numerous open stages.

Additionally, limited process control can lead to difficulties in achieving high reproducibility. An automated modular solution minimizes these risks by bringing multiple steps within a closed, highly regulated, and controlled system.

Improving Manufacturing Efficiency

Changing a manufacturing process requires multiple manual routines and adjustments that must be checked and documented. However, documentation and protocols are less helpful when a customized process is used because they only apply to that specific setup.

Standardization would effectively improve manufacturing efficiency. This approach would ensure that what is learned in one project can be referenced in future work, with data and documentation applicable across different technology applications. A modular chain of connected systems allows for process variation with instruments running in customized configurations. Additionally, having control of an individual instrument leads to the straightforward use of built-in software and sensors.

Automated Manufacturing: The Way Forward for Cell and Gene Therapy

By using automated manufacturing to minimize human interaction, time, and resource requirements, it is possible to increase production speed and lower some risks and costs associated with commercialization.

The industry is ever-changing and adjusting its complex, yet exciting challenges will take some time. However, automation can create a significant advantage over competitors, providing the tools needed to produce cell therapies with the highest levels of safety and efficacy for patients.

Per Hammer has two decades of experience in the biopharma industry, mainly supporting customers in academics through process development and manufacturing. Per joined Cytiva in 2001, taking on several distinct roles in the company. Most recently, he progressed from Product Manager Leader for the Bioprocess Automation and Digital Team to Senior Global Product Manager for the Cell & Gene Therapy Automation and Digital Solutions. He can be reached at per.hammer@cytiva.com.

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Automating the Genomic Medicines of the Future - Bio-IT World

Wilmington, Delaware, United States, July 18, 2022 (GLOBE NEWSWIRE) -- Transparency Market Research Inc.: The market value of the global cell separation technologies market is estimated to be over US$ 20.3 Bn by 2031, according to a research report by Transparency Market Research (TMR). Hence, the market is expected expand at a CAGR of 11.9% during the forecast period, from 2022 to 2031.

According to the TMR insights on the cell separation technologies market, the prevalence of chronic disorders including obesity, diabetes, cardiac diseases, cancer, and arthritis is being increasing around the world. Some of the key reasons for this situation include the sedentary lifestyle of people, increase in the older population, and rise in cigarette smoking and alcohol consumption across many developed and developing nations. These factors are expected to help in the expansion of the cell separation technologies market during the forecast period.

Players in the global cell separation technologies market are increasing focus on the launch of next-gen products. Hence, they are seen increasing investments in R&Ds. Moreover, companies are focusing on different strategies including acquisitions and strengthening their distribution networks in order to stay ahead of the competition.

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As per the Imperial College London, chronic diseases are expected to account for approximately 41 million deaths per year, which seven out of 10 demises worldwide. Of these deaths, approximately 17 million are considered to be premature. Hence, surge in cases of chronic diseases globally is resulting into increased need for cellular therapies in order to treat such disease conditions, which, in turn, is boosting the investments toward R&Ds, creating sales opportunities in the cell separation technologies market.

Cell Separation Technologies Market: Key Findings

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Cell Separation Technologies Market: Growth Boosters

Cell Separation Technologies Market: Regional Analysis

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Cell Separation Technologies Market: Key Players

Some of the key players profiled in the report are:

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Cell Separation Technologies Market Segmentation

Modernization of healthcare in terms of both infrastructure and services have pushed the healthcare industry to new heights, Stay Updated with Latest Healthcare Research Reports by Transparency Market Research:

Cell Culture Market: Rise in outsourcing activities and expansion of biopharmaceutical manufacturers are expected to drive the cell culture market during the forecast period

Cell Culture Media, Sera, and Reagents Market: The global cell culture media, sera, and reagents market is majorly driven by growth and expansion of biotechnology & pharmaceutical companies and academic & research institutes.

Stem Cells Market: The global stem cells market is majorly driven by rising applications of stem cells in regenerative medicines. Increase in the number of chronic diseases such as cardiac diseases, diabetes, cancer, etc.

Cell Line Authentication and Characterization Tests Market: Increase in the geriatric population and surge in incidence of chronic diseases are projected to drive the global cell line authentication and characterization tests market.

CAR T-cell Therapy Market: The CAR T-cell therapy market is expected to clock a CAGR of 30.6% during the assessment period. The CAR T-cell therapy is known as a revolutionary treatment option for cancer, owing to its remarkably effective and durable clinical responses.

Cell & Tissue Preservation Market: Rise in investments in the field of regenerative medicine research is estimated to propel the market. Human blood, tissues, cells, and organs own the capability to heal damaged tissues and organs with long-term advantages.

Placental Stem Cell Therapy Market: Placental stem cell therapy market is driven by prominence in treatment of age-related disorders/diseases and increase in awareness about stem cell therapies are projected to drive the global market in the near future.

Biotherapeutics Cell Line Development Market: The market growth will be largely driven by research and development activities due to which, new solutions and technologies have gradually entered the market.

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Cell Separation Technologies Market Expands with Rise in Prevalence of Chronic Diseases, States TMR Study - GlobeNewswire

Wilmington, Delaware, United States, Transparency Market Research Inc.: Medical nonwoven disposables are highly essential products in the healthcare field. Increase in popularity of these products has been observed as they provide better hygiene condition and reduce the contamination. Nonwoven products have many advantages over woven products.

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Nonwoven products include surgical gowns, face masks, drapes, surgeon caps, bandages, and others. Medical nonwoven disposables are made up from materials such as polypropylene, polyethylene, polyamides & polyesters, and others.

Medical nonwoven disposables products consist of high-quality fabrics for complete safety and immunity of healthcare professionals

The global medical nonwoven disposables market is driven by technological advancements in healthcare, increase in demand for advancements in wound dressing techniques, and rise in government initiatives for manufacturing nonwoven medical fabric. Moreover, demand for polyethylene is high due to low cost.

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Increase in prevalence of hospital-acquired infections among the geriatric population is expected to propel the medical nonwoven disposables market. According to the U.S. Department of Health & Human Product estimates, the U.S. is expected to have about 72.1 million geriatric population by 2030, which is more than twice the number in 2000.

As per a research paper published in the Current Opinion in Microbiology in 2018, lower respiratory tract infections which also include pneumonia, are the sixth leading cause of deaths due to hospitalizations in the U.S. and more than 90% of deaths occur in individuals who are 65 years old or more

Nonwoven medical disposables provide increased levels of protection against infectious diseases. In the past few years, nonwoven materials have shown significant reduction in post-operative infection rate compared to woven materials.

The risk of developing infection is nearly 2.5 times higher with woven products than nonwovens. Such factors help drive the medical nonwoven disposables market.

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Market Segmentation: Medical Nonwoven Disposables Market

Based on product, the global medical nonwoven disposables market has been divided into surgical products (drapes, gowns, caps, masks, and others), wound dressings (bandages, tapes, post-operative wound dressings, operative wound dressings, and dressing pads), and incontinence products (under pads and diapers)

In terms of material, the global medical nonwoven disposables market has been classified into polypropylene, polyethylene, acetate, rayon, polyamides & polyesters, acrylic, and others

In terms of end user, the global medical nonwoven disposables market has been categorized into hospitals, nursing homes, consumer & home healthcare, clinics, and ambulatory surgical centers

Each of the segments has been analyzed in detail for market trends, recent trends and developments, drivers, restraints, opportunities, and useful insights. The report provides current and future revenue (US$ Mn) for each of these segments from 2018 to 2028, considering 2019 as the base year. The compound annual growth rate (% CAGR) has been provided for each segment and market from 2020 to 2028 along with market size estimations.

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Regional Overview: Medical Nonwoven Disposables Market

In terms of region, the global medical nonwoven disposables market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The regions have been divided into major countries and sub-regions.

The current and future market value in terms of revenue (US$ Mn) of these regional markets and their major countries have been provided in the report from 2018 to 2028, with their CAGRs from 2020 to 2028.

The study also offers a list of recommendations, highlights, and useful insights of the market which would help new companies willing to enter the market and existing companies to increase market shares and help in the decision-making process.

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Major Players

The report concludes with the company profiles section that includes key information about the major players in the market

Leading players analyzed in the medical nonwoven disposables market include

Each of these players has been profiled in the report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments.

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Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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Medical Nonwoven Disposables Market: Increase in Demand for Advancements in Wound Dressing Techniques to Drive the Market - BioSpace

DUBLIN, July 15, 2022 /PRNewswire/ --The "Veterinary Medicine Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.

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The global veterinary medicine market reached a value of US$ 31.06 Billion in 2021. Looking forward, the publisher expects the market to reach a value of US$ 48.58 Billion by 2027, exhibiting a CAGR of 7.74% during 2021-2027. Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.

Veterinary medicine is a branch of science that deals in the prevention, control, diagnosis, and treatment of diseases that affect the health of domestic and wild animals. It helps maintain the health of food-producing animals, inhibit the transmission of zoonotic diseases from animal species to humans, and ensure a safe supply of food worldwide. At present, the escalating consumption of animal-derived products is increasing the adoption of veterinary medicines to monitor the health of agricultural animals and prevent human exposure to diseases.

The growing trend of nuclear families and inflating income levels have increased the overall spending of individuals on pets globally. This, in confluence with the rising concerns among pet parents about the well-being of their pets, represents one of the major factors supporting the demand for veterinary medicines.

The increasing penetration of pet insurance is further influencing the market growth. Apart from this, the expanding animal husbandry activities, along with the escalating cases of zoonotic and chronic diseases among animals, are increasing the concerns about food safety. This, along with the increasing number of commercial animal-production programs, is promoting the adoption of veterinary medicines for better diagnosis and treatment for livestock.

Moreover, the easy availability of advanced diagnostic imaging, novel therapies, nuclear and regenerative medicines, laser diagnostics, and specialized surgeries in numerous vet hospitals and clinics is bolstering the market growth. Furthermore, biomedical researchers are developing safe and effective vaccines to prevent pet diseases, which is anticipated to strengthen the market growth.

Competitive Landscape:

The competitive landscape of the industry has also been examined along with the profiles of the key players being Archer-Daniels-Midland Company, Boehringer Ingelheim GmbH, Cargill Incorporated, Ceva Sante Animale, Dechra Pharmaceuticals PLC, Elanco Animal Health Incorporated, Evonik Industries AG, Merck & Co. Inc., Neogen Corporation, Vetoquinol S.A., Virbac and Zoetis Inc.

Key Questions Answered in This Report:

How has the global veterinary medicine market performed so far and how will it perform in the coming years?

What has been the impact of COVID-19 on the global veterinary medicine market?

What are the key regional markets?

What is the breakup of the market based on the product?

What is the breakup of the market based on the animal type?

What is the breakup of the market based on the route of administration?

What is the breakup of the market based on the distribution channel?

What are the various stages in the value chain of the industry?

What are the key driving factors and challenges in the industry?

What is the structure of the global veterinary medicine market and who are the key players?

What is the degree of competition in the industry?

Key Topics Covered:

1 Preface

2 Scope and Methodology

3 Executive Summary

4 Introduction4.1 Overview4.2 Key Industry Trends

5 Global Veterinary Medicine Market5.1 Market Overview5.2 Market Performance5.3 Impact of COVID-195.4 Market Forecast

6 Market Breakup by Product6.1 Drugs6.1.1 Market Trends6.1.2 Key Segments6.1.2.1 Anti-infective6.1.2.2 Anti-inflammatory6.1.2.3 Parasiticide6.1.3 Market Forecast6.2 Vaccines6.2.1 Market Trends6.2.2 Key Segments6.2.2.1 Inactivated Vaccines6.2.2.2 Attenuated Vaccines6.2.2.3 Recombinant Vaccines6.2.3 Market Forecast6.3 Medicated Feed Additives6.3.1 Market Trends6.3.2 Key Segments6.3.2.1 Amino Acids6.3.2.2 Antibiotics6.3.3 Market Forecast

7 Market Breakup by Animal Type7.1 Production7.1.1 Market Trends7.1.2 Market Forecast7.2 Companion7.2.1 Market Trends7.2.2 Market Forecast

8 Market Breakup by Route of Administration8.1 Oral8.1.1 Market Trends8.1.2 Market Forecast8.2 Parenteral8.2.1 Market Trends8.2.2 Market Forecast8.3 Topical8.3.1 Market Trends8.3.2 Market Forecast

9 Market Breakup by Distribution Channel9.1 Veterinary Hospitals and Clinics9.1.1 Market Trends9.1.2 Market Forecast9.2 Point-of-Care Testing/In-house Testing9.2.1 Market Trends9.2.2 Market Forecast9.3 Others9.3.1 Market Trends9.3.2 Market Forecast

10 Market Breakup by Region

11 SWOT Analysis

12 Value Chain Analysis

13 Porters Five Forces Analysis

14 Price Analysis

15 Competitive Landscape15.1 Market Structure15.2 Key Players15.3 Profiles of Key Players15.3.1 Archer-Daniels-Midland Company15.3.1.1 Company Overview15.3.1.2 Product Portfolio15.3.1.3 Financials15.3.1.4 SWOT Analysis15.3.2 Boehringer Ingelheim GmbH15.3.2.1 Company Overview15.3.2.2 Product Portfolio15.3.3 Cargill Incorporated15.3.3.1 Company Overview15.3.3.2 Product Portfolio15.3.3.3 SWOT Analysis15.3.4 Ceva Sante Animale15.3.4.1 Company Overview15.3.4.2 Product Portfolio15.3.5 Dechra Pharmaceuticals PLC15.3.5.1 Company Overview15.3.5.2 Product Portfolio15.3.5.3 Financials15.3.6 Elanco Animal Health Incorporated15.3.6.1 Company Overview15.3.6.2 Product Portfolio15.3.6.3 Financials15.3.7 Evonik Industries AG15.3.7.1 Company Overview15.3.7.2 Product Portfolio15.3.7.3 Financials15.3.8 Merck & Co. Inc. 15.3.8.1 Company Overview15.3.8.2 Product Portfolio15.3.8.3 Financials15.3.9 Neogen Corporation15.3.9.1 Company Overview15.3.9.2 Product Portfolio15.3.9.3 Financials15.3.9.4 SWOT Analysis15.3.10 Vetoquinol S.A.15.3.10.1 Company Overview15.3.10.2 Product Portfolio15.3.10.3 Financials15.3.11 Virbac15.3.11.1 Company Overview15.3.11.2 Product Portfolio15.3.11.3 Financials15.3.11.4 SWOT Analysis15.3.12 Zoetis Inc.15.3.12.1 Company Overview15.3.12.2 Product Portfolio15.3.12.3 Financials15.3.12.4 SWOT Analysis

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Insights on the Veterinary Medicine Global Market to 2027 - by Product, Animal Type, Route of Administration, Distribution Channel and Region - Yahoo...

Competitors in the Market, 3M, Novartis AG, Aspect Biosystems, Kite Pharma, Misonix, Takeda Pharmaceutical Company Limited, Tego Science, Vericel Corporation, Smith & Nephew plc, Androgen Co., Ltd, Bluebird bio, Other Prominent Players

The global regenerative medicine market size was 18.1 billion in 2021. The global regenerative medicine market is forecast to grow to US$ 128.1 billion by 2030 by registering a compound annual growth rate (CAGR) of 21.1% during the forecast period from 2022 to 2030.

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The goal of the biomedical discipline of regenerative medicine is to repair damaged tissues and organs by renewing their structure and functionality. It involves the safe transplantation of stem cells made in the laboratory into the body to repair damaged bones, cartilage, blood vessels, and organs. Clinical therapeutic modalities include cell, immunomodulation, and tissue engineering frequently employ cellular and acellular regeneration drugs. They have the ability to treat a number of chronic conditions, including osteoporosis, Parkinsons disease, Alzheimers disease, and spinal cord injuries.

Factors Influencing the MarketThe growing geriatric population and rising cases of osteoporosis, Parkinsons disease, Alzheimers disease, and spinal cord injuries will fuel the demand for regenerative medicine during the study period. Apart from that, genetic disorders and cancer cases are also growing steeply, which will be opportunistic for the regenerative medicine market.

The rising healthcare sector all across the globe and favourable investments by government bodies will benefit the regenerative medicine market during the forecast period. Apart from that, rising investments in Research and Development aimed at enhancing the potential of regenerative medicine will also contribute to the growth of the regenerative medicine market during the forecast period. On the flip side, the high cost associated with regenerative medicine may act as a major restraint in the market growth during the forecast period.

COVID-19 Impact AnalysisThe demand for regenerative medicine is forecast to witness potential growth due to the COVID-19 pandemic. The pandemic highlighted the need to work on healthcare infrastructure. As a result of this, governments and private bodies started investing highly in the sector. Thus, it has been opportunistic for the regenerative medicine market during the forecast period.

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Regional AnalysisNorth America is expected to hold the highest share in the regenerative medicine market during the study period. The projected growth of this regional market will be due to the factors like high healthcare expenditure and increasing focus on stem cell banking, tissue engineering, and drug discovery in the region. Furthermore, the growing prevalence of disease and rising demand for stem cell therapy and cell immunotherapies will drive the growth of the regenerative medicine market. In addition, growing investments in the sector, combined with the early adoption of advanced technologies, will benefit this regional market during the study period.

Market SegmentationThe global regenerative medicine market segmentation focuses on Product, Application, End-User, and Region.By Product Type? Stem cell therapy? Biomaterial? Tissue Engineering? OthersBy Application? Bone Graft substitutes? Osteoarticular Diseases? Dermatology? Cardiovascular? Central Nervous System? OthersBy End-User? Hospitals? Special Clinics? Others

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By Region? North Americao The U.S.o Canadao Mexico? EuropeWestern Europeo The UKo Germanyo Franceo Italyo Spaino Rest of Western EuropeEastern Europeo Polando Russiao Rest of Eastern Europe? Asia Pacifico Chinao Indiao Japano Australia & New Zealando ASEANo Rest of Asia Pacific? Middle East & Africa (MEA)o UAEo Saudi Arabiao South Africao Rest of MEA? South Americao Brazilo Argentinao Rest of South America

What are the key findings of the report?

This report provides comprehensive information on factors expected to influence the market growth and market share in the future.

The report offers the current state of the market and future prospects for various geographical regions.

This report provides both qualitative and quantitative information about the competitive landscape of the market.

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Regenerative Medicine Market Latest, Segments Analysis and Opportunities 2022-2030 - Taiwan News

CHARLOTTE, NC, July 08, 2022 /24-7PressRelease/ An estimated 30 million Americans suffer from osteoarthritis. Osteoarthritis or degenerative arthritis is the most common type of arthritis. Its a painful, often debilitating, a condition caused when the cartilage or cushion between our joints breaks down, leaving bone to rub on bone. Osteoarthritis is a leading cause of hospitalization, resulting in over 600,000 joint replacement surgeries annually.

Baby boomers want to stay active, but there is an added factor to developing osteoarthritis from prior injuries. You have an increased risk of developing arthritis from injuries, such as a cartilage tear in the knee, even minor ones, in your 20s or 30s.

Once osteoarthritis sets in, common treatments include over-the-counter pain relievers, prescription medications, physical therapy, or chiropractic adjustmentsnone help improve the joints quality. When the pain gets too great, the last option is joint replacement.

For years, orthopedic surgeons have used regenerative medicine, such as Platelet-Rich Plasma (PRP), to help patients recover faster. As the field of regenerative medicine has grown, experienced physicians are emerging.

Dr. James Altizer, MD, is a board-certified medical doctor who has performed thousands of stem cell and PRP procedures since January 2016, making him the most experienced doctor in the Carolinas.

Osteoarthritis and Regenerative Medicine Treatment

Typically, traditional osteoarthritis treatment aims to control the symptoms and cover up the pain until its too late to save the joint. Dr. Altizer treats underlying arthritis by stimulating the bodys natural healing process using regenerative medicine.

Regenerative medicine deals with the process of replacing or regenerating human cells or tissues to restore normal function naturally. This new therapeutic strategy helps prevent osteoarthritis from advancing by stimulating tissue regeneration in the joints and reducing inflammation, which leads to a significant reduction in pain and improved physical activity levels.

At Neogenix, a leading regenerative medicine provider, we treat the patient, not just the pain. Our team provides a personalized treatment plan to improve the lives of those suffering from osteoarthritis using natural regenerative therapies. The first step is where we get to know the patient and give a thorough assessment to determine the root cause of their pain.

We are at a tipping point in medicine when it comes to using our bodies to heal ourselves, says Dr. Altizer. Our patients see a significant reduction in their arthritis pain level and improvement in overall function, which can prolong their active lifestyle for many years.

If you are suffering from arthritis pain and want to put off future joint replacement surgery, schedule a consultation with Dr. Altizer. Find out now if regenerative medicine can help repair tissue damage in your joints.

ABOUT NEOGENIXNeogenix has been a leading regenerative medicine provider in the Carolinas since 2020. Dr. James Altizer, MD, is a board-certified medical doctor who has performed thousands of stem cell and growth factor procedures since January 2016, making him the most experienced doctor in the Carolinas. These powerful, all-natural treatments regenerate and heal damaged tissues to get you back to living the life you deserve. They offer realistic assessments, not false hope or high-pressure sales tactics. Patients experience little to no downtime, and these all-natural, non-surgical treatments carry none of the potentially life-threatening risks of surgery.

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Regenerative Medicine is an Early Treatment for Osteoarthritis - Digital Journal

Privately-held UK-based company Mogrify and Japanese drugmaker Astellas (TYO: 4503) have signed a collaborative research agreement on in vivo regenerative medicine approaches to address sensorineural hearing loss.

Using Mogrifys proprietary direct cellular reprogramming platform, the collaboration will seek to identify novel combinations of transcription factors involved in cell differentiation to generate new cochlear hair cells.

As part of the

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Mogrify and Astellas link up on regenerative medicine approaches in sensorineural hearing loss - The Pharma Letter

Dublin, July 06, 2022 (GLOBE NEWSWIRE) -- The "Stem Cell Assays Market by Type (Viability, Proliferation, Differentiation, Apoptosis), Cell Type (Mesenchymal, iPSCs, HSCs, hESCs), Product & Service (Instrument), Application (Regenerative Medicine, Clinical Research), End User - Global Forecast to 2027" report has been added to ResearchAndMarkets.com's offering.

The stem cell assay market is projected to reach USD 4.5 Billion by 2027 from USD 1.9 Billion in 2022, at a CAGR of 17.7% during the forecast period.

The growth of the market is projected to be driven by collaborations and agreements among market players for stem cell assay products & services, the launch of new stem cell analysis systems such as flow cytometers, and increase in R&D expenditure by biopharmaceutical and biotechnology companies.The viability/cytotoxicity assays accounted for the largest share of the type segment in the stem cell assays market in 2021Cell viability assays help to determine the number of live and dead cells in a culture medium. The viability/cytotoxicity assays include various types such as tetrazolium reduction assays, resazurin cell viability assays, calcein-AM cell viability assays, and other viability/cytotoxicity assays. The cell viability/cytotoxicity market is likely to be driven by rising R&D spending on stem cell research, an increase in demand for stem cell assays in drug discovery, and development of new stem cell therapies..The adult stem cells segment accounted for the largest share of the cell type segment in the stem cell assays market in 2021.Adult stem cells account for the largest share of the stem cell assay market. The adult stem cells include mesenchymal stem cells, induced pluripotent stem cells, hematopoietic stem cells, umbilical cord stem cells, and neural stem cells. The growth of the adult stems cells segment is driven by the increasing usage of adult stem cells in regenerative medicine and the development of advanced therapies.Asia Pacific: The fastest-growing region in the stem cell assays marketThe Asia Pacific is estimated to be the fastest-growing segment of the market, owing to the rising prevalence of cancer & other diseases, increasing R&D spending on biopharmaceutical projects, and focus on developing stem cell-based therapies. In this region, China and Japan are the largest markets.

Key Topics Covered:

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights4.1 Stem Cell Assays Market Overview4.2 North America: Stem Cell Assays Market, by Product & Service and Country (2021)4.3 Stem Cell Assays Market Share, by Type, 2022 Vs. 20274.4 Stem Cell Assays Market Share, by Application, 20214.5 Stem Cell Assays Market: Geographic Growth Opportunities

5 Market Overview5.1 Introduction5.2 Market Dynamics5.2.1 Drivers5.2.1.1 Increasing Awareness About Therapeutic Potency of Stem Cells5.2.1.2 Increasing Funding for Stem Cell Research5.2.1.3 Rising Demand for Cell-Based Assays in Drug Discovery5.2.1.4 Collaborations and Agreements Among Market Players for Stem Cell Assay Products & Services5.2.1.5 Rising Incidence of Cancer5.2.2 Restraints5.2.2.1 Issues in Embryonic Stem Cell Research5.2.2.2 High Cost of Stem Cell Analysis Instruments5.2.3 Opportunities5.2.3.1 Emerging Economies5.2.3.2 Government Initiatives to Boost Stem Cell Research5.2.4 Challenges5.2.4.1 Lack of Infrastructure for Stem Cell Research in Emerging Economies5.2.4.2 Dearth of Trained and Skilled Professionals5.3 Ranges/Scenarios5.4 Impact of COVID-19 on Stem Cell Assays Market5.5 Trends/Disruptions Impacting Customers' Business5.6 Pricing Analysis5.6.1 Average Selling Prices of Products Offered by Key Players5.6.2 Average Selling Price Trend5.7 Technology Analysis

6 Stem Cell Assays Market, by Type6.1 Introduction6.2 Viability/Cytotoxicity Assays6.3 Isolation & Purification Assays6.4 Cell Identification Assays6.5 Proliferation Assays6.6 Differentiation Assays6.7 Function Assays6.8 Apoptosis Assays

7 Stem Cell Assays Market, by Cell Type7.1 Introduction7.2 Adult Stem Cells7.3 Human Embryonic Stem Cells

8 Stem Cell Assays Market, by Product & Service8.1 Introduction8.2 Instruments8.3 Kits8.4 Services

9 Stem Cell Assays Market, by Application9.1 Introduction9.2 Regenerative Medicine & Therapy Development9.3 Drug Discovery & Development9.4 Clinical Research

10 Stem Cell Assays Market, by End-User

11 Stem Cell Assays Market, by Region

12 Competitive Landscape

13 Company Profiles

Companies Mentioned

For more information about this report visit https://www.researchandmarkets.com/r/2i79h7

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Global Stem Cell Assays Market Projected to Reach $4.5 Billion by 2027 - GlobeNewswire

The Global Orthopedic Regenerative Medicine Marketreport provides an in-depth analysis of emerging trends, market drivers, development opportunities and market constraints that may affect the industrys market dynamics. Each market sector is examined in depth in Reports Globe, including products, applications and competition analysis.

The report was created using three different recognition systems. The first step requires in-depth primary and secondary research on a wide range of topics. Approvals, ratings and results based on accurate data obtained by industry specialists are the next step. The research derives an overall estimate of the market size using top-down methods. Finally, the research evaluates the market for a series of sections and subsections using information triangulation and market separation techniques.

Key Drivers & Barriers:

High-impact factors and rendering engines have been studied in the Orthopedic Regenerative Medicine market report to help readers understand the overall development. In addition, the report contains restrictions and challenges that may stand in the way of players. This will help users pay attention and make informed business-related decisions. The specialists also looked at the next business outlook.

In its latest report, ReportsGlobe offers a comprehensive overview of the Orthopedic Regenerative Medicine market with an emphasis on keyword dynamics including driving forces, constraints, opportunities, trends and detailed information on Orthopedic Regenerative Medicine market structure. Orthopedic Regenerative Medicine s market sales in the global market will increase as activities and advanced technology increase. With the outbreak of covid-19, companies have become very dependent on digital platforms to survive.

Orthopedic Regenerative Medicine Market Segmentation:

Orthopedic Regenerative Medicine Market, By Treatment Type (2017-2028)

Orthopedic Regenerative Medicine Market, By Disease Indication (2017-2028)

Orthopedic Regenerative Medicine Market, By End User (2017-2028)

Major Players Operating in the Orthopedic Regenerative Medicine Market:

Orthopedic Regenerative Medicine Market Segment Analysis

The market research explores new data in the Orthopedic Regenerative Medicine market report. It examines the market size in terms of the value of each segment, as well as how market dynamics are likely to change over time. The report then divides this information into types and proposed applications, with a breakdown by geography (North America, Asia, Europe, and the Rest of the World). In addition, the report examines the structure of the industry, offers growth, forecast period, revenue value and volume estimates in industrial applications, and provides clarity regarding industry competition.

Orthopedic Regenerative Medicine Market Report Scope

ATTRIBUTES

Description

ESTIMATED YEAR

2022

BASE YEAR

2021

FORECAST YEAR

2022 to 2028

HISTORICAL YEAR

2020

SEGMENTS COVERED

Types, Applications, End-Users, and more.

REPORT COVERAGE

Revenue Forecast, Company Ranking, Competitive Landscape, Growth Factors, and Trends

BY REGION

North America, Europe, Asia Pacific, Latin America, Middle East and Africa

Regional Analysis of the Orthopedic Regenerative Medicine Market:

The Orthopedic Regenerative Medicine Market research report details the ongoing market trends, development outlines, and several research methodologies. It illustrates the key factors that directly manipulate the Market, for instance, production strategies, development platforms, and product portfolio. According to our researchers, even minor changes within the product profiles could result in huge disruptions to the above-mentioned factors.

Goals and objectives of the Orthopedic Regenerative Medicine Market Study

The study thoroughly examines the profiles of major market players and their major financial aspects. This comprehensive business analysis report is useful for all new and existing participants when designing their business strategies. This report covers Orthopedic Regenerative Medicine s market output, revenue, market shares and growth rates for each key company and covers breakdown data (production, consumption, revenue and market shares) by regions, type and applications. Orthopedic Regenerative Medicine historical breakdown data from 2017 to 2021 and forecast for 2022-2028.

Global Orthopedic Regenerative Medicine Market Research Report 2022 2028

Chapter 1 Orthopedic Regenerative Medicine Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Global Orthopedic Regenerative Medicine Market Forecast

How Reports Globe is different than other Market Research Providers:

The inception of Reports Globe has been backed by providing clients with a holistic view of market conditions and future possibilities/opportunities to reap maximum profits out of their businesses and assist in decision making. Our team of in-house analysts and consultants works tirelessly to understand your needs and suggest the best possible solutions to fulfill your research requirements.

Our team at Reports Globe follows a rigorous process of data validation, which allows us to publish reports from publishers with minimum or no deviations. Reports Globe collects, segregates, and publishes more than 500 reports annually that cater to products and services across numerous domains.

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Orthopedic Regenerative Medicine Market Global Industry Research Analysis & Forecast 2022 to 2028 | Ortho Regenerative Technologies Inc.,...

Wilmington, Delaware, United States, Transparency Market Research Inc.: The global cranial implants market is expanding due to an increase in the number of brain cancer and trauma cases and rapid technological advancements for establishing effective and efficient treatment platforms for cranial reconstruction. The global cranial implants market was valued at more than US$ 792.0 Mn in 2017. It is projected to reach a value of US$ 1.4 Bn by 2026, expanding at a CAGR of more than 6.5% from 2018 to 2026. The global market is expanding at a relatively higher growth rate due to an increase in the geriatric population, rise in the prevalence of cancer and trauma cases, increase in the number of cranial surgeries, research and developmental activities in the health care sector in both developed and developing countries

The human head can be subjected to several impactful loadings, such as those taking place due to falls, injuries, road accidents, etc.. These loadings may result in skull fracture, and in some cases, part of the skull may need to be replaced by a biomedical implant. Accidents may also lead to brain swelling, which can be treated by decompressive craniectomy.

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Cranioplasty is a neurosurgical procedure that is used to repair cranial defects resulting due to traumatic brain injury (TBI), brain tumors, and hemorrhagic diseases. This procedure is conducted with the aid of cranial implants. Earlier, several different types of materials were used for cranioplasty. With technological advancements, new materials and technological interventions are available, providing specificity for the patient population according to the treatment and surgeon.

Increase in technological advancements, such as implant computer-aided design, 3-D printing, and regenerative medicine has resulted in the advent of 3-D-print patient-specific implants that can be made from a variety of materials, including polymer, ceramic, or metal. They are more effective and accurate for treatment and help surgeons achieve increased success rates. Also, factors such as a rise in the geriatric population, increase in demand for customized cranial implants, and rise in the number of injuries and road accidents are boosting the growth of the cranial implants market. Furthermore, an increase in research and development activities and studies and rise in awareness are also anticipated to boost the cranial implants market.

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The global cranial implants market has been segmented based on product, material, end-user, and region. In terms of product, the market has been classified into customized cranial implants and non-customized cranial implants. The non-customized cranial implants segment is expected to hold a significant share of the market, while the customized cranial implants segment is expected to expand at a significant CAGR of 7.1% during the forecast period. Customized cranial implants are considered to be specific and well-fitted according to the cranial defects, save operating room procedure time and aid surgeons, may render the procedure less invasive, and reduce the risk of infection and complications. Generally, non-customized implants comprise traditional methods for cranial implantation. The number of non-customized implant products available in the market is higher.

In terms of material, the global cranial implants market has been classified into polymer, ceramic, and metal. The metal segment is projected to hold a prominent share of the market, while the polymer segment is anticipated to expand at a significant CAGR during the forecast period. The metal segment is estimated to expand at a CAGR of 6.8% during the forecast period. The most commonly used metal is grade 5 surgical titanium (i.e., Ti-6Al-4V), usually referred to as titanium or Ti-6-4. Metal is used in the cranium for fixation devices (e.g., plates and screws), solid plates, or mesh, or in combination with other materials such as ceramic components or inert plastic. The availability and long-term success rates of metals such as titanium, specifically related to resistance to infections, have contributed to their leading position in the cranial implants market.

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In terms of end-user, the global cranial implants market has been classified into hospitals and neurosurgery specialty centers. The hospitals segment is expected to dominate the market and expand at a CAGR of 6.9% during the forecast period. This is due to a rise in the number of hospitals, high surgery volume, and rise in the number of medical professionals.

Based on region, the global cranial implants market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to dominate the global market and account for a prominent share in the coming years. The market in North America is primarily driven by a rapid increase in the geriatric population; rise in the patient population; high prevalence of trauma, injuries, road accidents, and brain cancer cases; and increase in the acceptance of technologically advanced cranial implants.

Moreover, increase in awareness among people, rise in the number of players and products, and substantial focus on research and development are anticipated to fuel the global cranial implants market in North America during the forecast period. According to The American Association for the Surgery of Trauma (AAST), in the U.S., traumatic brain Injury (TBI) is the single largest cause of death from injury. The market in Asia Pacific is anticipated to expand at a rapid pace during the forecast period. The market in the region is estimated to be augmented by the presence of a large base of geriatric population, government initiatives in the health care field, expansion in research and development activities, and improving health care infrastructure.

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Companies such as Zimmer Biomet, Stryker, Kelyniam Global Inc., accounted for a major share of the global market in 2017. Increase in the number of technological advancements, rise in approvals from government bodies, acquisitions and mergers, and research and development are the key factors strengthening the position of these players in the market. In October, 2018, OssDsign AB, a distributor and manufacturer of regenerative implants for facial and cranial reconstruction, received 510(k) clearance by the U.S. FDA for the marketing and sale of its latest product, OSSDSIGN Cranioplug. Its implant is used during neurosurgical procedures, and it is made from an osteoconductive calcium phosphate ceramic composition reinforced with a titanium mesh plate. In October 2018, Kelyniam Global Inc., , submitted its third 510(k) application to the FDA for expanding its line of custom implants. Companies are adopting the strategies of acquisitions and collaborations with parallel companies in order to improve and strengthen their presence in the global market.

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Cranial Implants Market: Increase in the Number of Brain Cancer and Trauma Cases to Drive the Market - BioSpace