Category Archives: Regenerative Medicine

MIAMI (PRWEB) November 11, 2014

GlobalStemCellsGroup, Inc. has announced plans to host a minimum of four international symposiums on stem cell research in 2015. The symposiums will be held in three Latin American countriesChile, Mexico and Colombiain which Global Stem Cells has established state-of-the-art stem cell clinics staffed with expert medical personnel trained in regenerative medicine, through the Regenestem Network.

The fourth symposium will be held in Miami.

The decision follows the success of the Global Stem Cells Groups first International Symposium on Stem Cells and Regenerative Medicine, held Oct. 2, 3 and 4 in Buenos Aires, Argentina. Global Stem Cells Group CEO Benito Novas says the Buenos Aires event, combined with its steady growth of new clinics throughout Latin America, has provided additional motivation to schedule more stem cell symposiums in an effort to further educate the medical community on the latest advancements in stem cell therapies.

Thanks to Global Stem Cells Groups growing network of world-class stem cell researchers, treatment practitioners and investors committed to advancing stem cell medicine, the company is rapidly moving closer to its goal of helping physicians to bring treatments into their offices for the benefit of patients.

More than 900 physicians, researchers and regenerative medicine experts from around the world attended the Buenos Aires symposium, and Novas expects that number to grow with upcoming conferences.

We will continue to bring together a variety of committed stem cell advocates from the U.S., Mexico, Greece, Hong Kong and other regions around the globe, to be joined by a team of knowledgeable speakers, each one presenting the future of regenerative medicine in their field of specialty, Novas says.

Regenerative medicine as a field is still in its infancy, according to Global Stem Cell Group President and CEO Benito Novas.

Our objective is to [open a dialogue among the worlds medical and scientific communities in order to advance stem cell technologies and translate them into point of care medicine to the best of out abilities, Novas says. Our mission is to bring the benefits of stem cell therapies to the physicians office safely, efficacy and compliance with the highest standards of care with safety, efficacy and complying with the highest standard of care the world has to offer.

The purpose of each symposium is to bring top stem cell scientists together to share their knowledge and expertise in regenerative medicine, and begin the process of separating myths from facts when it comes to stem cell science and technology.

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Global Stem Cells Group Announces Plans to Hold Four International Symposiums on Stem Cells and Regenerative Medicine ...

Epigenetics Stem Cells in Development Regenerative Medicine - Michael Boland, Scripps Institute
Speaker: Michael Boland, Ph.D., Research Associate, The Scripps Research Institute.

By: Alliance for Regenerative Medicine

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Epigenetics & Stem Cells in Development & Regenerative Medicine - Michael Boland, Scripps Institute - Video

Epigenetics Stem Cells in Development Regenerative Medicine - Allyson Moutri, UC San Diego
Speaker: Alysson Muotri, Ph.D., Assistant Professor, Department of Pediatrics/Cellular Molecular Medicine, UC San Diego.

By: Alliance for Regenerative Medicine

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Epigenetics & Stem Cells in Development & Regenerative Medicine - Allyson Moutri, UC San Diego - Video

Epigenetics Stem Cells in Development Regenerative Medicine - Pier Lorenzo, Sanford-Burnham
Speaker: Pier Lorenzo Puri, M.D., Ph.D., Associate Professor, Development, Aging Regeneration Program, Sanford-Burnham Medical Research Institute.

By: Alliance for Regenerative Medicine

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Epigenetics & Stem Cells in Development & Regenerative Medicine - Pier Lorenzo, Sanford-Burnham - Video

Epigenetics Stem Cells in Development Regenerative Medicine - Allen Wang, UC San Diego
Speaker: Allen Wang, Ph.D., Postdoctoral Fellow, Department of Pediatrics, UC San Diego.

By: Alliance for Regenerative Medicine

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Epigenetics & Stem Cells in Development & Regenerative Medicine - Allen Wang, UC San Diego - Video

Keynote: Molecular Regulation of Stem Cell Quiescence Activation
Keynote Speaker: Thomas Rando, M.D., Ph.D., Director, Glenn Center for the Biology of Aging, Stanford University School of Medicine.

By: Alliance for Regenerative Medicine

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Keynote: Molecular Regulation of Stem Cell Quiescence & Activation - Video

PUBLIC RELEASE DATE:

6-Nov-2014

Contact: Kirsty Doole kirsty.doole@oup.com 01-865-355-439 Oxford University Press

Oxford University Press (OUP) is pleased to announce the launch of Regenerative Biomaterials (RB), published in association with the Chinese Society for Biomaterials (CSBM).

Prof. Xingdong Zhang, President of CSBM and Editor-in-Chief of RB, said: "We are very delighted that the Chinese Society for Biomaterials finally has an official, international journal, through the joint efforts of the Society and Oxford University Press. Biomaterials, the rapid-growing high-tech materials, are necessities to safeguard people's health as pharmaceuticals do. While regenerative medicine has become a major component of modern medicine, biomaterials used for the regeneration and repair of tissues or organs have become a main direction for the development of the current biomaterials. Regenerative biomaterials, which could be interpreted as the biomaterials able to regenerate a living tissue or organ and thus permanently heal the damaged tissue or organ, are leading to a revolutionary change to contemporary biomaterials science and engineering and will promote the progress of modern medicine".

Regenerative Biomaterials aims to provide a leading international forum for the publication of original research papers, reviews, clinical case reports, and commentaries on the topics relevant to the development of advanced regenerative biomaterials. The journal will cover novel regenerative technologies and therapeutic approaches for the regeneration and repair of damaged tissues and organs.

Kimi Zeng, Assistant Consultant, Oxford University Press, commented: "Oxford University Press aims to work with the highest quality China-based English journals, to help Chinese authors publish in international journals, and to disseminate the best scholarship to the widest possible audience. We are excited about this promising new journal and this partnership will continue to strengthen the excellent science publishing programme at OUP".

RB gives preference to articles addressing biomaterials for communications among various disciplines involved with biomaterials, nanotechnologies, stem cell biology, regenerative medicine, and clinical medicine.

The journal will be officially launched in November 2014 and it will be open access online. Visit the website for more information, submission guidelines, and sign up to receive tables of contents by email or RSS: http://rb.oxfordjournals.org

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Oxford University Press launches new journal Regenerative Biomaterials

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Newswise In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez-Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection. This discovery lays the groundwork for a better understanding of the role progenitor cells can play in immune system response and could lead to the development of more effective therapies for a wide range of diseases.

The two-year study was published online October 30, 2014 ahead of print in the journal Current Biology.

Progenitor cells are the link between stem cells and fully differentiated cells of the blood system, tissues and organs. This maturation process, known as differentiation, is determined in part by the original environment that the progenitor cell came from, called the niche. Many of these progenitors are maintained in a quiescent state or "standby mode" and are ready to differentiate in response to immune challenges (such as stress, infection or disease).

Dr. Gabriel Ferguson, a postdoctoral fellow in the lab of Dr. Martinez-Agosto and first author of the study, built upon the lab's previous research that utilized the blood system of the fruit fly species Drosophila, showing that a specific set of signals must be received by progenitor cells to activate their differentiation into cells that can work to fight infection after injury. Dr. Ferguson focused on two genes previously identified in stem cells but not in the blood system, named Yorkie and Scalloped, and discovered that they are required in a newly characterized cell type called a lineage specifying cell. These cells then essentially work as a switch, sending the required signal to progenitor cells.

The researchers further discovered that when the progenitor cells did not receive the required signal, the fly would not make the mature cells required to fight infection. This indicates that the ability of the blood system to fight outside infection and other pathogens is directly related to the signals sent by this new cell type.

"The beauty of this study is that we now have a system in which we can investigate how a signaling cell uses these two genes Yorkie and Scalloped, which have never before been shown in blood, to direct specific cells to be made," said Dr. Martinez-Agosto, associate professor of human genetics. "It can help us to eventually answer the question of how our body knows how to make specific cell types that can fight infection."

Drs. Martinez-Agosto and Ferguson and colleagues next hope that future studies will examine these genes beyond Drosophila and extend to mammalian models, and that the system will be used by the research community to study the role of the genes Yorkie and Scalloped in different niche environments.

"At a biochemical level, there is a lot of commonality between the molecular machinery in Drosophila and that in mice and humans," said Dr. Ferguson. "This study can further our shared understanding of how the microenvironment can regulate the differentiation and fate of a progenitor or stem cell."

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UCLA Gene Discovery Shows How Stem Cells Can Be Activated to Help Immune System Respond to Infection

JACKSON, Tenn. (PRWEB) October 30, 2014

Dr. Roy Schmidt and the staff of the Pain Specialist Center will host a free seminar and question-and-answer session about regenerative medicine on Tuesday, Nov. 11 at 6 p.m. Held at the clinic at 15 Stonebridge Blvd. in Jackson, the hour-long event will allow attendees to ask questions about stem cell therapy and platelet rich plasma therapy in a relaxed atmosphere. Guests also will have the chance to talk to individuals who have received regenerative medicine treatments, which focus on helping patients relieve pain by supporting the healing process.

Stem cell therapy focuses on delivering the patients own stem cells to parts of the body that are in need. After adipose tissue (comprised of fat cells) is taken from the patients body, it is made into a stem cell concentrate. That concentrate is injected at the focal point of pain or area that needs healing. Schmidt, who is certified to administer stem cell therapy, was trained by Bioheart Chief Scientific Officer Kristin Comella. Comella has been recognized as a national leader in stem cell therapy.

Platelet rich plasma (PRP) or platelet concentrates have been studied extensively since the 1990s. While similar products previously used in medicine (fibrin glue) were very expensive, PRP provides a cost-effective alternative. Plasma concentrates seek to help the body continue the healing process and strengthen the weakened tissue. It is often used for tendon problems, in addition to issues with ligaments, muscles, meniscus, cartilage, bone, wound and intervertebral discs. The supplemental role of hyperbaric oxygen therapy will be discussed at the event, also.

A board certified anesthesiologist, Schmidt has practiced pain management in the Jackson area for two decades. The Pain Specialist Center provides consultation and pain management services to patients suffering from chronic pain syndromes and terminal cancer pain. Individuals can learn more by going online to http://beyondpills.com, http://nopainmd.com and http://hyperbaricoxygentherapies.com, calling 731-660-2056 or e-mailing info(at)beyondpills(dot)com. Event information is on Facebook at http://www.facebook.com/PainSpecialistCenter.

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Seminar on Regenerative Medicine Open to Public

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Newswise WASHINGTON, D.C., October 30, 2014 Researchers at the University of Washington have developed a way to use sound to create cellular scaffolding for tissue engineering, a unique approach that could help overcome one of regenerative medicines significant obstacles. The researchers will present their technique at the 168th meeting of the Acoustical Society of America (ASA), held October 27-31, 2014, at the Indianapolis Marriott Downtown Hotel.

The development of the new technique started with somewhat of a serendipitous discovery. The University of Washington team had been studying boiling histotripsy - a technique that uses millisecond-long bursts of high-intensity ultrasound waves to break apart tissue - as a method to eliminate cancerous tumors by liquefying them with ultrasound waves. After the sound waves destroy the tumors, the body should eliminate them as cellular waste. When the researchers examined these decellularized tissues, however, they were surprised by what the boiling left intact.

In some of our experiments, we discovered that some of the stromal tissue and vasculature was being left behind, said Yak-Nam Wang, a senior engineer at the University of Washingtons Applied Physics Laboratory. So we had the idea about using this to decellularize tissues for tissue engineering and regenerative medicine.

The structure that remains after decellularizing tissues is known as the extracellular matrix, a fibrous network that provides a scaffold for cells to grow upon. Most other methods for decellularizing tissues and organs involve chemical and enzymatic treatments that can cause damage to the tissues and fibers and takes multiple days. Histrostipsy, on the other hand, offers the possibility of fast decellularization of tissue with minimal damage to the matrix.

In tissue engineering, one of the holy grails is to develop biomimetic structures so that you can replace tissues with native tissue, Wang said. Stripping away cells from already developed tissue could provide a good candidate for these structures, since the extracellular matrix already acts as the cellular framework for tissue systems, Wang said.

Due to its bare composition, the matrix also induces only a relatively weak immune response from the host. The matrix could then theoretically be fed with stem cells or cells from the same person to effectively re-grow an organ.

The other thought is that maybe you could just implant the extracellular matrix and then the body itself would self-seed the tissues, if its just a small patch of tissue that youre replacing, Wang said. You wont have any immune issues, and because you have this biomimetic scaffold thats closer to the native tissue, healing would be better, and the body would recognize it as normal tissue.

Wang is currently investigating decellularization of kidney and liver tissue from large animals. Future work involves increasing the size of the decellularized tissues and assessing their in-vivo regenerative efficacy.

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High-Intensity Sound Waves May Aid Regenerative Medicine