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Category Archives: Regenerative Medicine

The Veterinary Cooperative (TVC) and Vet-Stem, Inc. Announce an Exclusive Partnership to Offer Regenerative Medicine …

Posted: August 6, 2013 at 11:50 am

Poway, California (PRWEB) August 06, 2013

The worlds leading Regenerative Veterinary Medicine company out of San Diego California, Vet-Stem, Inc., has entered into an exclusive partnership with The Veterinary Cooperative (TVC) that will allow over 300 member hospitals to immediately start offering Vet-Stems stem cell therapy and other Regenerative Veterinary Medicine services. Vet-Stems services have been used to treat over 10,000 animals in the last 10 years ranging from horses and dogs, to exotic cats and dolphins. Veterinarians using Vet-Stem cell therapy treat and conduct studies on traumatic and degenerative diseases, including bowed tendons, ligament injuries, osteoarthritis, and osteochondral defects.

We are incredibly excited and appreciative to have become a long term exclusive provider to one of the countrys premier veterinary cooperatives. TVC is an excellent organization with tremendous leadership and members. Together we will help implement, train and grow the regenerative medicine business in each of the Hospitals associated with TVC. We very much admire the vision of TVC and all of its members in engaging in the future of regenerative medicine as true advanced medicine, Robert Harman, DVM, CEO of Vet-Stem, Inc.

After carefully reviewing all regenerative medicine possibilities over the last year we have proudly chosen to incorporate Vet-Stem, Inc. and their regenerative services as our exclusive partner to carry us through the coming years. We believe regenerative medicine is a large part of the future of veterinary medicine. We chose Vet-Stem because they have 10 years in business, 11 peer reviewed papers and have done over 10,000 procedures to date. We feel the quality they can offer is simply unmatched, as well as the fact there is no upfront cost associated with using their industry leading services. We also had a chance to work hand-in-hand with their field services veterinarian who offers excellent in-clinic training, marketing ideas and customer service. We are very excited to now offer Vet-Stems services through all of our TVC member hospitals, Rich Morris, CEO of TVC.

Based in Evanston, Illinois, The Veterinary Cooperative is a member-owned cooperative serving independent veterinarians and animal hospitals nationwide. TVC is managed by professional cooperative personnel and guided by a board of directors elected by and comprised of member/owners. All profits will be returned to TVC member veterinarians in the form of rebate distributions.

About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine visit http://www.vet-stem.com or call 858-748-2004.

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The Veterinary Cooperative (TVC) and Vet-Stem, Inc. Announce an Exclusive Partnership to Offer Regenerative Medicine ...

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Advance in regenerative medicine could make reprogrammed cells safer while improving their function

Posted: August 2, 2013 at 6:46 pm

Aug. 1, 2013 The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

The researchers' study, published in today's issue of the journal Nature, found that an enzyme, activation-induced cytidine deaminase (AID), helps in the process that changes an adult human cell into an induced pluripotent stem cell (iPS cell). These iPS cells can then be developed into any kind of cell needed to therapeutically restore tissues and organs.

The finding settles an ongoing controversy regarding use of AID to reprogram cells, says the study's senior investigator, Dr. Todd Evans, vice chair for research and professor of cell and developmental biology in the Department of Surgery at Weill Cornell Medical College.

"The dispute was whether AID is required to make iPS cells, and we found that the enzyme does make reprogramming very efficient, although it is not absolutely necessary," says Dr. Evans, an internationally-recognized authority on regenerative medicine. "In fact, we plan to test if reprogramming iPS cells without AID may even be helpful."

One reason is that AID can cause genetic mutations that can lead to cancer. AID is best known as a master regulator of antibody diversity in B cells, and in order to create varied types of beneficial antibodies, it routinely mutates antibody genes. But sometimes the process goes awry, resulting in development of B cell lymphoma, Dr. Evans says. "That leads us to believe that if you can reprogram cells without AID, it could reduce risk of potential mutations, and thus be safer."

iPS Cells Without AID Remember What They Once Were

In order to push a cell, such as a fibroblast, to revert to an iPS cell, the epigenetic "markers" that define an adult cell must be removed. "All cells of the body have the same genes, but they are used differently in different tissues," Dr. Evans explains. "If an undifferentiated cell becomes a heart cell, somehow it has to lock in and stabilize that particular adult phenotype and not forget what it is."

One way that function is accomplished is by placing a methylation group on top of certain genes that activate other cell destinations -- such as to become a liver cell -- usually switching those genes off. "We have known how these marks are put on genes, but we didn't know how they were taken off in the process of pushing an adult cell to revert back to a stem-cell-like state," Dr. Evans says.

Dr. Evans and his colleagues found that the AID enzyme removed those epigenetic markers.

They then created a mouse that did not produce AID to see if the animal's adult fibroblast cells could be pushed back to iPS cells. "If you need AID to reprogram the cells, you shouldn't be able to do it, or do it well."

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Advance in regenerative medicine could make reprogrammed cells safer while improving their function

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StemCells, Inc. Launches Alzheimer’s Disease Program Supported by California Institute for Regenerative Medicine

Posted: July 31, 2013 at 2:46 am

NEWARK, Calif., July 30, 2013 (GLOBE NEWSWIRE) -- StemCells, Inc. (STEM) today announced that it has formally launched its Alzheimer's disease program, which is being supported by the California Institute for Regenerative Medicine (CIRM). The goal of the project is to file, within four years, an Investigational New Drug (IND) application with the U.S. Food and Drug Administration to evaluate the Company's proprietary HuCNS-SC(R) product candidate (purified human neural stem cells) as a potential therapeutic in the treatment of Alzheimer's disease. CIRM has agreed to provide approximately $19.3 million to the Company in the form of a forgivable loan to help fund preclinical development and IND-enabling activities, and the Company recently received an initial disbursement of $3.8 million from CIRM. The funding was awarded under CIRM's Disease Team Therapy Development Award program (RFA 10-05) in September 2012.

"With CIRM's support, we have taken the first steps towards the development of a novel cell-based therapeutic for use in the treatment of Alzheimer's disease," commented Eliseo Salinas, MD, Executive Vice President and Head of Research & Development at StemCells, Inc. "Today, there are no good treatment options for Alzheimer's disease; in particular, there are no approved drugs which alter the progression of the disease. Furthermore, in the past few years, several drugs have failed in late-stage clinical trials. These drugs, like most of the treatments currently in development, target a single modality in a complex disease believed to result from a biological cascade probably triggered by multiple genetic and environmental factors. Cell-based therapies have the potential to provide a therapeutic benefit by acting on several relevant biological targets under the regulation of the host."

"We know from the preclinical work that our proprietary HuCNS-SC cells survive in the toxic environment of the Alzheimer's disease brain and restore memory under the regulation of the host. So rather than targeting a single mechanism in this cascade, our strategy is to provide healthy, self-renewing cells that can halt or slow disease progression and therefore preserve or restore cognitive function. Even a modest slowing of disease progression could translate into substantial improvements in quality of life for patients and families, as well as significant economic savings for society."

StemCells, Inc. will evaluate its HuCNS-SC cells as a potential therapeutic in Alzheimer's disease in collaboration with researchers at the University of California, Irvine (UCI) led by Frank LaFerla, Ph.D., a world-renowned researcher in the field, and Matthew Blurton-Jones, Ph.D. In July 2012, Dr. Blurton-Jones presented data at the Alzheimer's Association Annual Meeting demonstrating that the Company's neural stem cells restored memory and significantly enhanced synaptic function in two animal models relevant to Alzheimer's disease. Importantly, these results were observed in the presence of amyloid deposition and increased tau, two toxic hallmarks of the disease, and provide the basis for a fundamentally different and novel approach to the treatment of Alzheimer's disease.

About Alzheimer's Disease

Alzheimer's disease is a progressive, fatal neurodegenerative disorder that results in loss of memory and cognitive function. Today there is no cure or effective treatment option for patients afflicted by Alzheimer's disease. According to the Alzheimer's Association, approximately 5.4 million Americans have Alzheimer's disease, including nearly half of people aged 85 and older, and the prevalence of the disease is expected to increase rapidly as a result of the country's aging population. Moreover, the costs of the disease to society are significant - recent estimates range from $150 to $200 billion per year in the United States, with approximately three-quarters of those costs resulting from daily care either at home or in nursing facilities.

About CIRM

CIRM was established in November 2004 with the passage of Proposition 71, the California Stem Cell Research and Cures Act. The statewide ballot measure, which provided $3 billion in funding for stem cell research at California universities and research institutions, was overwhelmingly approved by voters, and called for the establishment of an entity to make grants and provide loans for stem cell research, research facilities, and other vital research opportunities. A list of grants and loans awarded to date may be seen here: http://www.cirm.ca.gov/for-researchers/researchfunding.

About StemCells, Inc.

StemCells, Inc. is engaged in the research, development, and commercialization of cell-based therapeutics and tools for use in stem cell-based research and drug discovery. The Company's lead therapeutic product candidate, HuCNS-SC(R) cells (purified human neural stem cells), is currently in development as a potential treatment for a broad range of central nervous system disorders. In a Phase I clinical trial in Pelizaeus-Merzbacher disease (PMD), a fatal myelination disorder in children, the Company has shown preliminary evidence of progressive and durable donor-derived myelination in all four patients transplanted with HuCNS-SC cells. The Company is also conducting a Phase I/II clinical trial in chronic spinal cord injury in Switzerland and Canada and has reported positive interim data for the first three patients. The Company is also conducting a Phase I/II clinical trial in dry age-related macular degeneration (AMD), and is pursuing preclinical studies in Alzheimer's disease. StemCells also markets stem cell research products, including media and reagents, under the SC Proven(R) brand. Further information about StemCells is available at http://www.stemcellsinc.com.

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StemCells, Inc. Launches Alzheimer's Disease Program Supported by California Institute for Regenerative Medicine

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BCC Research Predicts Regenerative Medicines Market for Bone and Joint Applications to Reach $3.9 Billion by 2018

Posted: July 25, 2013 at 4:46 pm

Wellesley, MA (PRWEB) July 25, 2013

In the new report, Regenerative Medicines: Bone and Joint Applications (Report Code: PHM032C), from BCC Research (http://www.bccresearch.com), the regenerative medicines market for bone and joint applications was valued at $2.72 billion in 2012 and is expected to reach $2.72 billion in 2013. The report forecasts total market value to reach $3.9 billion in 2018, after increasing at a five-year compound annual growth rate (CAGR) of 7.3%.

In this report, BCC Research has identified bone replacement and grafting as the largest market within these applications, accounting for nearly 90% of market share in some niches. The two other main markets within this area of regenerative medicines are the electrical and ultrasound bone growth stimulators market and the cell therapy and tissue-engineered cartilage market.

Regenerative medicine is an area of research and development that includes stem cell research and its applications. The uses include treating and curing diseases with limited and no treatment options. For example, the successful differentiation of embryonic stem cells into specific cell types is widely sought as a means to treat traumatic spinal-cord injury, as well as diseases such as diabetes, Duchenne muscular dystrophy, heart disease, and vision and hearing loss. This new report from BCC Research shows how regenerative therapies have the potential to improve medical outcomes, enhance quality of life, and reduce overall healthcare costs.

A key objective identified by BCC Research in this report is the utilization of living cells to repair or replace body tissue damaged by injury, disease or the aging process. The most successful products have drawn upon multidisciplinary fields such as biology, medicine, engineering, and biomedical engineering. Other regenerative applications such as dental, neurologic, organ regeneration, cardiovascular, urologic, and diabetes are also potential targets for therapeutic applications.

BCC Research has identified a number of drivers impacting the growth in the bone and joint applications of regenerative medicines. The main growth drivers include greater familiarity with regenerative medicine products, an expanding technology base, more clinical trials, increased academic research at top academic and government research institutions, and a growing patient base.

The report predicts that regenerative medicine will dramatically alter the U.S. healthcare industry. There are enormous potential benefits from regenerative medicine in terms of both improved healthcare and economic savings. One area where this will occur is in organ replacement. The costs associated with direct organ replacement total $350 billion or roughly 8% of global healthcare spending. A $350 billion global industry already built on the base of first-generation tissue and organ therapy products and substitutes, regenerative medicine has the technical potential to exceed $500 billion in the next 20 years.

The information and analysis presented in this report will prove crucial in decision making for managers involved in business development, marketing, market research, product development, mergers and acquisitions, licensing, business management, investment banking, and deal creation. The report is also advantageous for consultants involved in pharmaceutical and biotechnology industries.

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BCC Research Predicts Regenerative Medicines Market for Bone and Joint Applications to Reach $3.9 Billion by 2018

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BioTime CEO Dr. Michael West to Present at the Case Western Reserve University 6th Annual Regenerative Medicine …

Posted: July 16, 2013 at 12:49 pm

ALAMEDA, Calif.--(BUSINESS WIRE)--

BioTime, Inc. (NYSE MKT: BTX), a biotechnology company that develops and markets products in the field of regenerative medicine, announced that Chief Executive Officer Michael D. West, PhD will present today at the Case Western Reserve University in the meeting The Business of Regenerative Medicine: From Stem Cells to the Market Place in Cleveland, Ohio. Dr. Wests presentation titled Embryomics: Commercial Opportunities in the Increasing Complex Biology of Pluripotency is scheduled for 11:00 a.m. EDT. Dr. West will describe new data relating the company's PureStem technology and cell lines potentially useful in the treatment of Alzheimer's disease and for Alzheimer's disease research and will soon be made available for sale to the research community.

The presentation is available on BioTimes website at http://www.biotimeinc.com/scientific-presentations. A discussion of the results presented in todays meeting is also discussed by Dr. West in his weekly video update available for viewing at http://www.biotimeinc.com/video-series/.

About BioTime, Inc.

BioTime, headquartered in Alameda, California, is a biotechnology company focused on regenerative medicine and blood plasma volume expanders. Its broad platform of stem cell technologies is enhanced through subsidiaries focused on specific fields of application. BioTime develops and markets research products in the fields of stem cells and regenerative medicine, including a wide array of proprietary PureStem cell lines, HyStem hydrogels, culture media, and differentiation kits. BioTime is developing Renevia (formerly known as HyStem-Rx), a biocompatible, implantable hyaluronan and collagen-based matrix for cell delivery in human clinical applications. BioTime's therapeutic product development strategy is pursued through subsidiaries that focus on specific organ systems and related diseases for which there is a high unmet medical need. BioTime's majority owned subsidiary Cell Cure Neurosciences Ltd. is developing therapeutic products derived from stem cells for the treatment of retinal and neural degenerative diseases. BioTime's subsidiary OrthoCyte Corporation is developing therapeutic applications of stem cells to treat orthopedic diseases and injuries. Another subsidiary, OncoCyte Corporation, focuses on the diagnostic and therapeutic applications of stem cell technology in cancer, including the diagnostic product PanC-Dx currently being developed for the detection of cancer in blood samples. ReCyte Therapeutics, Inc. is developing applications of BioTime's proprietary induced pluripotent stem cell technology to reverse the developmental aging of human cells to treat cardiovascular and blood cell diseases. BioTime's subsidiary LifeMap Sciences, Inc. markets GeneCards, the leading human gene database, as part of an integrated database suite that also includes the LifeMap Discovery database of embryonic development, stem cell research and regenerative medicine, and MalaCards, the human disease database. LifeMap Sciences also markets BioTime research products and PanDaTox, an innovative, recently developed, searchable database that can aid in the discovery of new antibiotics and biotechnologically beneficial products. Asterias Biotherapeutics, Inc. is a new subsidiary being used to acquire the stem cell assets of Geron Corporation, including patents and other intellectual property, biological materials, reagents and equipment for the development of new therapeutic products for regenerative medicine. BioTime's lead product, Hextend, is a blood plasma volume expander manufactured and distributed in the U.S. by Hospira, Inc. and in South Korea by CJ CheilJedang Corporation under exclusive licensing agreements. Additional information about BioTime can be found on the web at http://www.biotimeinc.com.

Forward-Looking Statements

Statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development, and potential opportunities for BioTime and its subsidiaries, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, and maintenance of intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the business of BioTime and its subsidiaries, particularly those mentioned in the cautionary statements found in BioTime's Securities and Exchange Commission filings. BioTime disclaims any intent or obligation to update these forward-looking statements.

To receive ongoing BioTime corporate communications, please click on the following link to join our email alert list: http://news.biotimeinc.com

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BioTime CEO Dr. Michael West to Present at the Case Western Reserve University 6th Annual Regenerative Medicine ...

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The Alliance for Regenerative Medicine Holds Third Annual Stem Cell Meeting on the Mesa Regen Med Partnering Forum

Posted: July 16, 2013 at 12:49 pm

WASHINGTON, DC--(Marketwired - Jul 16, 2013) - The Alliance for Regenerative Medicine (ARM), the international organization representing the interests of the regenerative medicine community, today announced that the third annual Regen Med Partnering Forum will take place October 14 and 15, 2013 as part of the Stem Cell Meeting on the Mesa. This forum is the only partnering meeting organized specifically for the regenerative medicine field, and has become the premier gathering place for more than 300 senior level executives seeking opportunities to collaborate and learn more about recent advances in the space. Life Technologies Corporation (NASDAQ: LIFE) is the meeting's founding and platinum-level sponsor.

The Regen Med Partnering Forum will take place at the Estancia La Jolla Hotel & Spa, La Jolla, California. The Stem Cell Meeting on the Mesa's eighth Annual Scientific Symposium will immediately follow the Regen Med Partnering Forum on October 16, 2013 at the Salk Institute for Biological Studies. The Scientific Symposium, organized by the Sanford Consortium for Regenerative Medicine, is attended by leading scientists and researchers in the field, as well as participants from the business and patient advocacy communities. Combined, these meetings will attract over 800 attendees from around the globe, highlighting the promise and progress of this rapidly evolving, interdisciplinary field.

"Stem Cell Meeting on the Mesa is the premier annual meeting for anyone involved in regenerative medicine, cell therapy and stem cell research," said Geoff MacKay, President & Chief Executive Officer of Organogenesis Inc. and Chairman of ARM. "The quality of speakers -- both industry and academic -- combined with high-level partnering opportunities, makes attending this meeting every year a top priority."

In addition to presentations by 40 cutting-edge companies seeking partners and investors, the Regen Med Partnering Forum will include interactive panels addressing critical commercial, scientific, regulatory and reimbursement issues. One-on-one meetings will also be scheduled with a state-of-the-art partnering system to connect participants. The Regen Med Partnering Forum was developed by the Alliance for Regenerative Medicine (ARM) and the California Institute for Regenerative Medicine (CIRM) in 2011 and has grown 35% over the past three years.

"Life Technologies has sponsored this meeting since its inception in 2006, and helped it grow into a leading, annual conference for the regenerative medicine community," said Alaine Maxwell, Associate Director, Americas Marketing, Stem Cells and Translational Research, Life Technologies. "Whether your goal is to gain exposure to researchers or put your name out in front of C-level executives, attending this meeting has incredible value."

To learn more or to register for the 2013 Stem Cell Meeting on the Mesa please visit http://www.stemcellmeetingonthemesa.com. Registration is complimentary for investors and credentialed members of the media.

About The Alliance for Regenerative MedicineThe Alliance for Regenerative Medicine (ARM) is a Washington, DC-based multi-stakeholder advocacy organization that promotes legislative, regulatory and reimbursement initiatives necessary to facilitate access to life-giving advances in regenerative medicine. ARM also works to increase public understanding of the field and its potential to transform human healthcare, providing business development and investor outreach services to support the growth of its member companies and research organizations. Prior to the formation of ARM in 2009, there was no advocacy organization operating in Washington, DC to specifically represent the interests of the companies, research institutions, investors and patient groups that comprise the entire regenerative medicine community. Today ARM has more than 140 members and is the leading global advocacy organization in this field. To learn more about ARM or to become a member, visit http://www.alliancerm.org.

About Life Technologies Life Technologies Corporation (NASDAQ: LIFE) is a global biotechnology company that is committed to providing the most innovative products and services to leading customers in the fields of scientific research, genetic analysis and applied sciences. With a presence in more than 180 countries, the company's portfolio of 50,000 end-to-end solutions is secured by more than 5,000 patents and licenses that span the entire biological spectrum -- scientific exploration, molecular diagnostics, 21st century forensics, regenerative medicine and agricultural research. Life Technologies has approximately 10,000 employees and had sales of $3.8 billion in 2012.

Life Technologies' Safe Harbor Statement This press release includes forward-looking statements about our anticipated results that involve risks and uncertainties. Some of the information contained in this press release, including, but not limited to, statements as to industry trends and Life Technologies' plans, objectives, expectations and strategy for its business, contains forward-looking statements that are subject to risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by such forward-looking statements. Any statements that are not statements of historical fact are forward-looking statements. When used, the words "believe," "plan," "intend," "anticipate," "target," "estimate," "expect" and the like, and/or future tense or conditional constructions ("will," "may," "could," "should," etc.), or similar expressions, identify certain of these forward-looking statements. Important factors which could cause actual results to differ materially from those in the forward-looking statements are detailed in filings made by Life Technologies with the Securities and Exchange Commission. Life Technologies undertakes no obligation to update or revise any such forward-looking statements to reflect subsequent events or circumstances.

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The Alliance for Regenerative Medicine Holds Third Annual Stem Cell Meeting on the Mesa Regen Med Partnering Forum

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Regenerative Medicines: Bone and Joint Applications

Posted: July 3, 2013 at 1:47 am

NEW YORK, July 2, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Regenerative Medicines: Bone and Joint Applications http://www.reportlinker.com/p0157460/Regenerative-Medicines-Bone-and-Joint-Applications.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Blood_Supply,_Tissue_Banking_and_Transplantation

INTRODUCTION

Regenerative medicine in orthopedic applications is a $2.7 billion per year niche sector in America's $2.6 trillion per year healthcare system. However, it is a sector of immense interest in terms of technical and medical possibilities. The best analogy to the current state of regenerative therapies in the bone and joint healing sector is the nascency of the microprocessors business back in 1971. At that time, microprocessors (namely Intel's 4004), and related innovations, were just an infinitesimal segment of electronic component sales, but this innovation came to dominate the economy. The regenerative therapies sector, particularly areas such as cell therapy and stem cell derived products is in a comparable position today.

The regenerative medicine industry has been in existence for nearly 25 years. Actual product sales, along with research and development (R&D) expenditures, are projected to amount to approximately $2.7 billion in economic activity in 2013, of which venture capital and R&D funding accounts for about $145 million. The rapid evolution of this business is evidenced by the industry consolidation that has occurred since the first edition of this BCC Research report was published in 2003 and even since the most recent edition in 2009. Innumerable buyouts, consolidations, product abandonments, new firms and a few bankruptcies, too, have occurred in just the last several years. These changes are reflected in the Company Profiles section of this report. In addition, intensive R&D efforts at universities, the National Institutes of Health, the National Science Foundation and at FDA centers that focus on cuttingedge technology underscore the importance of this industry.

Regenerative therapies have the potential to improve medical outcomes, enhance quality of life, and reduce overall healthcare costs. A key objective is the utilization of living cells to repair or replace body tissue damaged by injury, disease, or the aging process. The most successful products have drawn upon multidisciplinary fields such as biology, medicine, engineering, and, particularly, biomedical engineering.

The principal focus in this report is on bone and joint applications; however, other regenerative applications such as dental, neurologic, organ regeneration, cardiovascular, urologic, diabetes, and wound care are important and are briefly covered to underscore the larger importance of regenerative therapies. Stemcell research is an important component of the sector as well. For example, the successful differentiation of embryonic stem cells into specific cell types is widely sought as a means to treat traumatic spinalcord injury, as well as diseases such as diabetes, Duchenne muscular dystrophy, heart disease, and vision and hearing loss.

OBJECTIVES AND GOALS OF STUDY

This report focuses on the bone and jointrelated applications of and markets for the various categories of regenerative medicine products currently available and projected to be introduced during the fiveyear forecast period from 2013 through 2018. Market drivers discussed include the status of R&D and what is likely to issue from R&D in the way of actual products and therapies. Other market drivers include the incidence, and rate of growth, of diseases and disorders that will benefit from these products, primarily arthritis, osteoporosis, and various types of bone and joint trauma (e.g., hip fractures, knee injuries); increasing use of nonautograft products by physicians; and innovative devices that incorporate bone and cartilagegrowthstimulating agents in a regenerative appliance. Products discussed include bone and cartilage grafting and regenerative products derived from autologous, allogeneic, and synthetic sources, as well as electrical stimulators for bone growth and regenerative cartilage products.

Profiles are provided of leading and emerging companies in the bone and joint regenerative medicine markets, along with analyses of the current and future positioning of their products and businesses in this active and rapidly changing market. Developmental and clinical stage companies are well covered.

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Regenerative Medicines: Bone and Joint Applications

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Terumo BCT – World Stem Cells Regenerative Medicine Congress 2013 – Video

Posted: June 28, 2013 at 12:50 pm


Terumo BCT - World Stem Cells Regenerative Medicine Congress 2013
We spoke with some of the sponsors at Europe #39;s largest stem cells and regenerative medicine industry conference. This is a three day congress that stages a s...

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Terumo BCT - World Stem Cells Regenerative Medicine Congress 2013 - Video

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Savsu Technologies – World Stem Cells Regenerative Medicine Congress 2013 – Video

Posted: June 27, 2013 at 12:47 pm


Savsu Technologies - World Stem Cells Regenerative Medicine Congress 2013
We spoke with some of the sponsors at Europe #39;s largest stem cells and regenerative medicine industry conference. This is a three day congress that stages a s...

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Savsu Technologies - World Stem Cells Regenerative Medicine Congress 2013 - Video

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Keynote address – Lord John Krebs – World Stem Cells Regenerative Medicine Congress – Video

Posted: June 25, 2013 at 1:52 pm


Keynote address - Lord John Krebs - World Stem Cells Regenerative Medicine Congress
Lord John Krebs, chairman of the House of Lords Science and Technology Committee gives his presentation on #39;Mapping a route for the commercialisation of cell...

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Keynote address - Lord John Krebs - World Stem Cells Regenerative Medicine Congress - Video

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