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Category Archives: Regenerative Medicine

454: A Documentary About Stem Cell Research – Video

Posted: November 9, 2012 at 2:50 am


454: A Documentary About Stem Cell Research
In 2004 Alex Goldberg, then a 20 year old local filmmaker began a documentary on stem cell research at the University of Washington. On June 16 2011, he died before the film was finished. This film highlights the need for this research to continue in order to save thousands of lives. In this unsettling political climate, the film resonates. It was made during the Bush era when stem cell lines were limited, thus stunting the research and in turn a cure for so many diseases. Many thanks to Dr Charles Murry and his staff for their tireless efforts to create therapies in regenerative medicine. Dr Murry may be reached through the University of Washington research labs. If you would like to make donations to help fund this research and the researchers who work without appropriate compensation please click the following link: depts.washington.eduFrom:Leta GoldbergViews:94 3ratingsTime:15:03More inEducation

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umbilical cord stem cells | Cord Blood Storage and Why – Video

Posted: November 9, 2012 at 2:50 am


umbilical cord stem cells | Cord Blood Storage and Why
http://www.cordbloodrecommendation.com By preserving this cord blood through cord blood banking, your baby will be ensured a perfect source of cells in the event of some unfortunate accident, disease or other life threatening illness. Safety is a concern in the public banks because of the high cost of maintaining the storage unit. Besides this, children without siblings and people belonging to certain races or ethnicities, who don #39;t have access to other people of their race in their area, also face problems. Sources of stem cells, such as blood, fats, bone, or umbilical cords were simply named as sources, not as natural resources. By preserving your baby #39;s cord blood, you are actually saving your child from the dangers of waiting for matching donors during emergencies. ""Regenerative medicine is the next evolution of medical treatments. Stromal cells are a kind of cells that form bone, cartilage, fat, and fibrous connective tissue. There are people who are against this practice as well and there are many opinions supporting it too therefore it is best to consult your doctor regarding this issue and get the right advice. For this, the patient needs a donor whose tissues and cells match his own. In case the cord blood is collected before the removal of placenta, the umbilical cord is clamped and detached as usual. - Stem groups can be certainly obtained from cord blood- flex blood stem groups are a 100% reach for the patron, 50% reach for biological parents and 25% reach for blood ...From:Alexander santafeViews:1 0ratingsTime:01:13More inScience Technology

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Keynote Speaker: Daniel Kraft • Presented by SPEAK Inc. – Video

Posted: November 9, 2012 at 2:50 am


Keynote Speaker: Daniel Kraft bull; Presented by SPEAK Inc.
Stanford and Harvard Trained Physician-Scientist, Inventor, Entrepreneur and Innovator Dr. Daniel Kraft has over 20 years of experience in clinical practice, biomedical research and healthcare innovation. Daniel chairs the Medicine track for Singularity University and is Executive Director for FutureMed, a program which explores convergent, exponentially developing technologies and their potential in biomedicine and healthcare. Following undergraduate degrees at Brown and medical school at Stanford, Dr. Kraft was board certified in the Harvard combined Internal Medicine and Pediatrics residency program at the Massachusetts General Hospital and Boston Children`s Hospital. He went on to complete Stanford fellowships in hematology/oncology bone marrow transplantation, and extensive research in stem cell biology and regenerative medicine. He has multiple scientific publications (including in Nature and Science), medical device, immunology and stem cell related patents through faculty positions with Stanford University School of Medicine and as clinical faculty for the pediatric bone marrow transplantation service at UCSF. Dr. Kraft recently founded IntelliMedicine, focused on enabling connected, data driven, and integrated personalized medicine. He is also the inventor of the MarrowMiner, an FDA approved device for the minimally invasive harvest of bone marrow, and founded RegenMed Systems, a company developing technologies to enable adult stem cell based regenerative ...From:speakincViews:0 0ratingsTime:14:53More inPeople Blogs

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Texas Can Become Center for Regenerative Medicine

Posted: November 9, 2012 at 2:50 am

Gov. Rick Perry today highlighted Texas leading role in the advancement of regenerative medicine to produce safe, effective and ethical adult stem cell therapies. The governor spoke at the inaugural Houston Stem Cell Summit, which focuses on adult stem cell research and its potential to tackle life-threatening diseases.

Im proud Texas is playing a key role in the advancement of adult stem cell research and therapies, both of which are promising for patients and our economy, Gov. Perry said. This conference represents another step in the growth of this industry that I hope and expect will be centered right here in the Lone Star State.

Texas has taken clear steps to advance research in ethical regenerative medicine as quickly and safely as possible, while protecting patients receiving these treatments in the state. Earlier this year, the Texas Legislature, Texas Medical Board and Texas Department of Health and Human Services set up a regulatory framework to guide companies, institutions and physicians collaborating to produce effective stem cell research.

Additionally, Texas continues to attract top researchers in biotechnology and regenerative medicine thanks to our commitment to investing in the technologies of the future through the Cancer Prevention Research Institute of Texas (CPRIT) and Texas Emerging Technology Fund (TETF). CPRIT has funded 427 awards totaling more than $756 million for cancer research, commercialization and prevention in academic institutions, non-profit organizations and private companies. The TETF has invested more than $180 million in grant-matching and research superiority funds in Texas universities, and more than $194 million in 137 early-stage companies, with more than $103 million of that going directly to biotechnology and life science companies.

Texas researchers have also received more than $52 million in National Institute of Health (NIH) funding in 2009 for adult stem cell studies. These grants have resulted in the Austin Heart Hospital successfully treating heart attack patients with adult stem cells, and success in treating spinal cord injuries and a variety of heart conditions.

The Houston Stem Cell Summit highlights the latest research and breakthroughs regarding the use of adult stem and progenitor cell therapies. The summit covers all aspects of emerging stem cell therapies including the latest in peer reviewed academic stem cell research, breakthroughs in adult stem cell therapies, patient experiences, the business of stem cell therapies and the evolving regulatory environment for stem cell therapies. For more information, please visit http://www.stemcellsummit.com/houston/. To view the governors full remarks, please visit http://governor.state.tx.us/news/speech/17803/

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Fat-derived Stem Cells Hold Potential for Regenerative Medicine

Posted: November 9, 2012 at 2:50 am

PHILADELPHIA As researchers work on reconfiguring cells to take on new regenerative properties, a new review from Penn Medicine plastic surgeons sheds additional light on the potential power of adipose-derived stem cells - or adult stem cells harvested from fatty tissue - in reconstructive and regenerative medicine.

Reconstructive plastic surgeons have clinically integrated "fat grafting" into different surgeries for years, for breast, facial, and other reconstructive and restorative surgeries, with good success. Now, researchers are beginning to understand the power that fatty tissue holds. This new paper, published in the Aesthetic Surgery Journal, enforces that adipose-derived stem cells can be routinely isolated from patients and, once molecular methods are worked out, may be useful for a multitude of regenerative medicine applications.

"The opportunities for regenerative medicine interventions based on adult stem cells are tremendous. It is critically important for us to better understand the biology of these cells so that we can develop novel, safe and effective treatments for our patients using their own cells." said the paper's senior author, Ivona Percec, MD, PhD, assistant professor in the division of Plastic Surgery in the Perelman School of Medicine at the University of Pennsylvania.

Many groups are looking into different modes of isolating and modifying these cells for their regenerative properties, including experts at Penn's Institute for Regenerative Medicine and around Penn Medicine. For example, Dr. Percec's team is conducting translational research into the mechanisms controlling adipose-derived stem cells, and how they contribute to the normal human aging process.

Stem cells can undergo multiple divisions without differentiation, making them useful tools for cell-replacement therapy. Embryonic stem cells can convert to any cell type, whereas adult stem cells, like the stem cells derived from fat, can differentiate into many, but not all, cell types. A person's own fat tissue could then potentially be converted into cells specially designed to repair damage to the heart, cartilage, blood vessels, brain, muscle, or bone.

As regenerative medicine techniques are refined, experts will continue to explore the utility and benefits of stem cells derived from adipose tissue.

The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.

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Midwest regenerative medicine symposium to be held in Cincinnati

Posted: November 9, 2012 at 2:50 am

Public release date: 5-Nov-2012 [ | E-mail | Share ]

Contact: Katie Pence katie.pence@uc.edu 513-558-4561 University of Cincinnati Academic Health Center

CINCINNATIHoxworth Blood Center, the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center will host the Midwest Symposium on New Concepts For Tissue-Specific Regenerative Medicine, Nov 16-17, 2012, in Rieveschl Auditorium of the Vontz Center for Molecular Studies.

The symposium, also being co-sponsored and co-funded by UC's Center for Clinical and Translational Science and Training (CCTST), will focus on research and collaboration regarding regenerative medicinethe process of regenerating human cells, tissues or organs to restore or establish normal function.

The field holds the promise of repairing damaged tissues and organs in the body by stimulating the body's own repair mechanisms or by growing replacement tissues in labs.

Jose Cancelas, MD, PhD, professor of pediatrics at the UC College of Medicine and director of the research division at Hoxworth Blood Center, is a co-organizer of the symposium and says regenerative medicine expertise is very strong in the region.

"The purpose of the symposium will be to create a forum where investigators and their groups can meet and share ideas and data," he says. "In addition, it will serve as an excellent platform for regional scientific interactions for investigators, postdocs and students that have interest in regenerative medicine and stem cell biology. Hopefully, this meeting will spark collaborations locally and regionally."

Specifically, the meeting will focus on research using stem cells in the body, or those manipulated in a petri dish, to study disease, generate therapeutic tissues and create genetic therapies.

Keynote speakers will deliver addresses followed by short oral presentations with extended discussions to allow interaction among attendees.

"Research presentations will span from how scientists are looking at the use of stem cells to assist with gastrointestinal, pancreas, lung, corneal, skeletal muscle, vascular and cardiac regeneration to genetic therapies and how this research could and is translating to treatment," Cancelas says. "There's a wealth of scientific and clinical stem cell work being done right here in Cincinnati.

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Midwest regenerative medicine symposium to be held in Cincinnati

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Keynote Speaker: Daniel Kraft • Presented by SPEAK Inc. – Video

Posted: November 8, 2012 at 4:42 pm


Keynote Speaker: Daniel Kraft bull; Presented by SPEAK Inc.
Stanford and Harvard Trained Physician-Scientist, Inventor, Entrepreneur and Innovator Dr. Daniel Kraft has over 20 years of experience in clinical practice, biomedical research and healthcare innovation. Daniel chairs the Medicine track for Singularity University and is Executive Director for FutureMed, a program which explores convergent, exponentially developing technologies and their potential in biomedicine and healthcare. Following undergraduate degrees at Brown and medical school at Stanford, Dr. Kraft was board certified in the Harvard combined Internal Medicine and Pediatrics residency program at the Massachusetts General Hospital and Boston Children`s Hospital. He went on to complete Stanford fellowships in hematology/oncology bone marrow transplantation, and extensive research in stem cell biology and regenerative medicine. He has multiple scientific publications (including in Nature and Science), medical device, immunology and stem cell related patents through faculty positions with Stanford University School of Medicine and as clinical faculty for the pediatric bone marrow transplantation service at UCSF. Dr. Kraft recently founded IntelliMedicine, focused on enabling connected, data driven, and integrated personalized medicine. He is also the inventor of the MarrowMiner, an FDA approved device for the minimally invasive harvest of bone marrow, and founded RegenMed Systems, a company developing technologies to enable adult stem cell based regenerative ...From:speakincViews:0 0ratingsTime:14:53More inPeople Blogs

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Fat-derived Stem Cells Hold Potential for Regenerative Medicine

Posted: November 8, 2012 at 4:42 pm

PHILADELPHIA As researchers work on reconfiguring cells to take on new regenerative properties, a new review from Penn Medicine plastic surgeons sheds additional light on the potential power of adipose-derived stem cells - or adult stem cells harvested from fatty tissue - in reconstructive and regenerative medicine.

Reconstructive plastic surgeons have clinically integrated "fat grafting" into different surgeries for years, for breast, facial, and other reconstructive and restorative surgeries, with good success. Now, researchers are beginning to understand the power that fatty tissue holds. This new paper, published in the Aesthetic Surgery Journal, enforces that adipose-derived stem cells can be routinely isolated from patients and, once molecular methods are worked out, may be useful for a multitude of regenerative medicine applications.

"The opportunities for regenerative medicine interventions based on adult stem cells are tremendous. It is critically important for us to better understand the biology of these cells so that we can develop novel, safe and effective treatments for our patients using their own cells." said the paper's senior author, Ivona Percec, MD, PhD, assistant professor in the division of Plastic Surgery in the Perelman School of Medicine at the University of Pennsylvania.

Many groups are looking into different modes of isolating and modifying these cells for their regenerative properties, including experts at Penn's Institute for Regenerative Medicine and around Penn Medicine. For example, Dr. Percec's team is conducting translational research into the mechanisms controlling adipose-derived stem cells, and how they contribute to the normal human aging process.

Stem cells can undergo multiple divisions without differentiation, making them useful tools for cell-replacement therapy. Embryonic stem cells can convert to any cell type, whereas adult stem cells, like the stem cells derived from fat, can differentiate into many, but not all, cell types. A person's own fat tissue could then potentially be converted into cells specially designed to repair damage to the heart, cartilage, blood vessels, brain, muscle, or bone.

As regenerative medicine techniques are refined, experts will continue to explore the utility and benefits of stem cells derived from adipose tissue.

The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.

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Texas Can Become Center for Regenerative Medicine

Posted: November 6, 2012 at 8:42 pm

Gov. Rick Perry today highlighted Texas leading role in the advancement of regenerative medicine to produce safe, effective and ethical adult stem cell therapies. The governor spoke at the inaugural Houston Stem Cell Summit, which focuses on adult stem cell research and its potential to tackle life-threatening diseases.

Im proud Texas is playing a key role in the advancement of adult stem cell research and therapies, both of which are promising for patients and our economy, Gov. Perry said. This conference represents another step in the growth of this industry that I hope and expect will be centered right here in the Lone Star State.

Texas has taken clear steps to advance research in ethical regenerative medicine as quickly and safely as possible, while protecting patients receiving these treatments in the state. Earlier this year, the Texas Legislature, Texas Medical Board and Texas Department of Health and Human Services set up a regulatory framework to guide companies, institutions and physicians collaborating to produce effective stem cell research.

Additionally, Texas continues to attract top researchers in biotechnology and regenerative medicine thanks to our commitment to investing in the technologies of the future through the Cancer Prevention Research Institute of Texas (CPRIT) and Texas Emerging Technology Fund (TETF). CPRIT has funded 427 awards totaling more than $756 million for cancer research, commercialization and prevention in academic institutions, non-profit organizations and private companies. The TETF has invested more than $180 million in grant-matching and research superiority funds in Texas universities, and more than $194 million in 137 early-stage companies, with more than $103 million of that going directly to biotechnology and life science companies.

Texas researchers have also received more than $52 million in National Institute of Health (NIH) funding in 2009 for adult stem cell studies. These grants have resulted in the Austin Heart Hospital successfully treating heart attack patients with adult stem cells, and success in treating spinal cord injuries and a variety of heart conditions.

The Houston Stem Cell Summit highlights the latest research and breakthroughs regarding the use of adult stem and progenitor cell therapies. The summit covers all aspects of emerging stem cell therapies including the latest in peer reviewed academic stem cell research, breakthroughs in adult stem cell therapies, patient experiences, the business of stem cell therapies and the evolving regulatory environment for stem cell therapies. For more information, please visit http://www.stemcellsummit.com/houston/. To view the governors full remarks, please visit http://governor.state.tx.us/news/speech/17803/

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GEN’s “Cellular Therapy Wave Finally Cresting”. An overview and data set.

Posted: November 4, 2012 at 8:01 am


We first provided a listing (with very few details) of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials on this blog late last year (see the posting here).

We are now pleased to we have worked with Genetic Engineering and Biotechnology News and Enal Razvi of Select Biosciences to provide an updated (as of June 2012) and more detailed listing of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials (excluding cell-based immunotherapies which we intend to cover in a follow-up article).

A link to the listing can be found in an article published today entitled "Cellular Therapy Wave Finally Cresting" found in the November 1, 2012 issue of GEN.  

While not my favorite title, the article is a brief - but we hope useful - overview of the sector and its pipeline.  It also provides a snapshot of the cell therapy products already in commercial distribution. 
Some will quibble about the numbers. Certainly others have published larger revenue numbers, for instance, but in our view these have almost always included revenue from cord blood banking which we have excluded.
We encourage you to read the article but for convenience here is a direct link to the spreadsheet.  Of course it's already out-dated but we'll do an update again soon here on this blog.


Hope this is useful.
--Lee


Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ctijFXeY01M/gens-cellular-therapy-wave-finally.html

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