Category Archives: Stem Cell Research

Park Ki-Young stepped down as the head of a newly-created science centre, which is responsible for allocating $18 billion in government subsidies and budgets for research projects, a blow to President Moon Jae-In

A top South Korean technology official accused of covering up a notorious stem cell research fraud resigned Friday, a blow to new President Moon Jae-In.

Park Ki-Young stepped down as the head of a newly-created science centre, which is responsible for allocating $18 billion in government subsidies and budgets for research projects.

"I sincerely apologize for causing such disappointment and controversy," Park said in a statement.

"I hope my resignation will serve as an opportunity for the country's science sector to pull together again for development", she added.

Park, a former biology professor seen as a key figure in a scandal involving the fabrication of research by prominent stem cell scientist Hwang Woo-Suk, had been under heavy pressure to step down after hundreds of South Korean scientists protested her appointment by Moon this week.

Hwang was lauded as the "pride of Korea" after claiming to have derived stem cell lines from cloned human embryosa world firstin two articles published in the journal Science in 2004 and 2005.

But his research was later found to be fraudulent and riddled with ethical lapses.

Park played a key role in supporting Hwang and his research projects with generous government subsidies when she served as a presidential aide for science and technology from 2004 to 2006.

She was also one of 15 co-authors of one of Hwang's Science papers.

She resigned from her role as a presidential aide at that time after being accused of covering up crucial flaws in Hwang's stem cell study and sweeping under the carpet ethical lapses involved in his projects that used many human eggs.

Explore further: Outrage over S.Korean stem cell scandal official's new post

2017 AFP

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S. Korea stem cell scandal official resigns - Phys.Org

Im often asked about the safety of treatments that purport to inject stem cells into painful body parts. The reputation of stem cells seems to exceed the reach, with companies touting treatments that arent FDA approved or even being tested.

Back in March, an alarming article in the New England Journal of Medicinedescribed three women blinded by stem cell treatments two of the patients reported seeing a reference on the company website to registration at the National Institutes of Healths well-respected ClinicalTrials.gov, and assuming it applied to their treatment. It didnt.

In what is perhaps a modern version of hawking snake oil, companies can indeed register certain clinical trials without breaking any rules but desperate patients might not know that.

There is no doubt that some patients have misinterpreted a studys listing on ClinicalTrials.gov as a stamp of legitimacy, federal review, and compliance. In this way, treatments with no safety or efficacy data, no prior clinical study, and no ongoing clinical trials under FDA review, appear to have federal approval. Such a misunderstanding can lead to disastrous outcomes for patients, said Thomas Albini, MD, of the Bascom Palmer Eye Institute of the University of Miami, who treated the blinded women.

When I wrote about the disaster here at DNA Scienceand atMedscape Medical News, my Medscape editor asked me to take a closer look at criteria for listing investigations at ClinicalTrials.gov. It proved an interesting exercise, but I declined to write an article, fearing lawsuits if I named companies.

ClinicalTrials.gov is where research groups, in academia and pharma/biotech, describe protocols to evaluate the safety and efficacy of new drugs, biologics, and devices, which FDA regulates, typically in randomized, controlled trials. But for an observational study that just follows what happens after a treatment, no such thumbs-up is required; no investigational new drug (IND) designation or investigational device exemption (IDE) need be filed. And that creates a loophole that companies are happily jumping through and luring patients in pain, who may know little about clinical trial design, and perhaps trust too much the companies and the doctors offering these services.

Its easy to see how people are fooled. One company claims that By providing access to registered clinical studies through the NIH, we are providing patients with the ability to choose a stem cell treatment center with the highest standard of care. If the treatment is experimental, how can there even be a standard of care?

MOST STUDIES LEGIT

I love ClinicalTrials.gov its packed with information about all manner of conditions, with contacts and references. I started my investigation by searching for studies that sounded bogus.

I began with a treatment that epitomizes pseudoscience: magnets. But I was fooled. Other than legit uses in medical devices, my magnet search called up as an acronym of sorts for theMothers and Girls Dancing Together Trial, a well-designed study on preventing childhood obesity, with a decent sample size and controls.

I also thought the randomised crossover trial of the acute effects of a deep-fried Mars bar or porridge on the cerebral vasculature was fake, but it turned out to be a medical students project, well done, and published in the Scottish Medical Journal.

But trial NCT02833532, sponsored by a Korean pharmaceutical company, was likely a joke, with the stated purpose of temporary penile enhancement and one of the investigators first name being Dong. Participants must answer the question How do you rate your penile size? Very small/small/normal/big/very big to enroll. Those accepted get to try something made of hyaluronic acid, which is found, coincidentally, in cocks combs.

Searching ClinicalTrials.gov for stem cells returns more than 4,000 entries, so I gave up. Fortunately, Leigh Turner, PhD, associate professor at the Center for Bioethics at the University of Minnesota, wasnt afraid of lawyers and took a more measured, scholarly approach. He recently published the intriguing findings in Regenerative Medicine, where you can find nice tables naming the stem cell companies that use and possibly abuse ClinicalTrials.gov.

AN ACADEMIC INVESTIGATION

Dr. Turner searched ClinicalTrials.gov for stem cells along with patient-sponsored, patient-funded, and self-funded because expecting patients to pay is a red flag. Only a very few real clinical trials charge patients, and those that do must have FDA approval to do so.

He found 7 such pay-as-you-go clinical trials, each enrolling more than 100 people, at the government website, and another 11 in a database of companies that provide direct-to-consumer stem-cell-based treatments. The DTC label indicates that the treatments arent part of a real experimental protocol. One of themhad signed up more than 3,000 gullible people.

The companies that charge patients yet proclaim a ClinicalTrials.gov listing are having their proverbial cake and eating it too borrowing the governmental veneer of a sanctioned clinical trial, while collecting fees. And many health care consumers arent even aware theyre being bamboozled.

Another red flag in a stem cell pitch is an everything-but-the-kitchen-sink list of targets. Stem Cell Network, for example, claims to be able to treat, using stem cells grown from a patients fat, some 28 conditions, including the vague knee problems, and also muscular dystrophy, ankle problems, neuropathy, asthma, and alopecia areata. Also be wary of stem cells derived from one body part like butt fat being injected into another body part such as eyeballs.

Wed like people to protect themselves by going to a reliable website, like ClinicalTrials.gov, to distinguish legitimate from bogus claims of stem cell clinics. But the findings of this paper challenge that advice because this valuable resource, which is designed to promote transparency and to help people find clinical trials, lists unlicensed and unproven stem cell interventions that companies turn into personal marketing platforms. So if you have ALS, MS, Parkinsons disease, a ClinicalTrials.gov listing looks like any other study on the NIH website. Many people think a listing is credible, Dr. Turner told me.

There is an urgent need for careful screening of clinical studies before they are registered with ClinicalTrials.gov, Dr. Turners paper concludes. But in the current climate of a nuclear threat, a health care system in disarray, and possible cuts to the CDC, FDA, and NIH, ramping up scrutiny at ClinicalTrials.gov is unlikely to have priority, if the President even has a clue what it is.

Its not possible to slash, burn, defund, and deregulate at every turn and think that federal agencies are going to improve how they function. But no administration is forever, no budget is forever, deregulatory moments dont last forever, and perhaps problems that are ignored or neglected now will be addressed in the future, with collateral damage along the way while nothing is done, warns Dr. Turner, who lives in Canada. I wonder if he has a spare room.

Those seeking stem cell treatments should check out the International Society for Stem Cell Research (ISSCR) Patient Handbook on Stem Cell Therapiesand stemcells.nih.gov. Alas, much of the media is still somewhat unfamiliar with the biology of stem cells, that they are not cells that can turn into any cell typebut that they self-renew and jettison a new stem cell at every division. Thats what makes them stem cells, not the ability to spawn specialized cells.

So I tell people who ask me if they should have stem cells shot into their aching knees or backs to do so only if they wouldnt object to an abnormal growth cancer forming there.

When it comes to stem cell therapies, its caveat emptor buyer beware!

Original post:
Are Stem Cell Companies Abusing ClinicalTrials.gov? - PLoS Blogs (blog)

Even though Richard Lopez is still in high school, he can already tell you a thing or two about the ureteric bud, the metanephric mesenchyme and the developing kidney.

More impressively, he was familiar with these terms before starting his summer internship in the lab of Andy McMahon, kidney researcher and director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC.

I knew I was going to come here, Lopez said. So from December on, I was just reading papers that were written by Dr. McMahons lab. And so I read about the development of the kidney, kidney organoids, experimental methods like in situ hybridization, immunohistochemistry, all that stuff. Im really glad I did all of that because now that Im here, I understand whats going on.

Lopez undertook this intense preparation as part of the Science Research Program at his Connecticut boarding school, Choate Rosemary Hall. In addition to familiarizing him with the McMahon labs research, the program provided experience with useful molecular biology techniques, ranging from gel electrophoresis to polymerase chain reaction.

Lopez didnt start his high school career at Choate. Growing up in Lennox near the Los Angeles International Airport, he attended local public schools until his sophomore year in high school. At that point, his exceptional scores on the California Standardized Test attracted the attention of the Young Eisner Scholar program, which empowers underserved students to fulfill their potential.

As an Eisner Scholar, he earned both admission and a full scholarship to attend Choate. But the decision to leave home wasnt easy.

I was terrified at first, leaving everything behind, he said. I talked to my mom about it, and at first she was hesitant because I was born and raised here, and Im the only child. But then she realized that this is an amazing opportunity, and I cant let it go by.

Lopez recalls that Choate was initially in a huge culture shock from the occasional Maserati to the international student body to the exceptional academic opportunities such as the Science Research Program that brought him to USC.

In the McMahon lab, Lopez has learned about the molecular signals that drive the branching development of the kidney, and he has practiced a wide range of lab techniques.

Im really excited about science because I know its potential.

Richard Lopez

Im really excited and passionate about science because I know its potential, he said. If you pair that with math, you have no boundaries. If you look at the lab where Im working right now creating kidney organoids, learning about kidney development, these kinds of things can solve really burdensome illnesses that are fatal to some people, like end-stage renal disease and polycystic kidney disease.

To get to the lab every day, Lopez bike commutes a total of 32 miles from his home in Lennox to USCs Health Sciences Campus. Hes run the Los Angeles Marathon once and the San Francisco Marathon twice. In November, hes planning to travel to Florida to celebrate his 18th birthday with his first Ironman Triathlon a 2.4-mile swim, 112-mile bike ride and 26.2-mile run.

Hes participating in these events not only for fun and fitness, but also as a way to give back. Hes currently raising sponsorship money for the Partnership Scholars Program, which provides underserved junior high and high school students with educational and cultural experiences, ranging from theatergoing to restaurant outings to college tours. His goal is to raise $54,000 to fund three new scholars.

I was very lucky, he said. So I want to raise money for the scholarships that have helped me out along the way.

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High school student gets an early start in stem cell research at USC - USC News

Irvine, Calif., July 26, 2017 A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

Weian Zhao, associate professor of pharmaceutical sciences, and colleagues have programmed human bone marrow stem cells to identify the unique physical properties of cancerous tissue. They added a piece of code to their engineered cells so that they can detect distinctively stiff cancerous tissue, lock into it and activate therapeutics.

Our new type of treatment only targets metastatic tissue, which enables us to avoid some of conventional chemotherapys unwanted side effects, Weian Zhao said. Steve Zylius / UCI

In a study appearing in Science Translational Medicine, the researchers report they have effectively and safely employed this stem cell-targeting system in mice to treat metastatic breast cancer that had spread to the lung. They first transplanted the engineered stem cells to let them find and settle into the tumor site where they secreted enzymes called cytosine deaminase. The mice were then administered an inactive chemotherapy called prodrug 5-flurocytosine, which was triggered into action by the tumor site enzymes.

Zhao said his team specifically focused on metastatic cancer, which comes when the disease spreads to other parts of the body. Metastatic tumors are particularly deadly and the cause of 90 percent of cancer deaths.

This is a new paradigm for cancer therapy, Zhao said. We are going in a direction that few have explored before, and we hope to offer an alternative and potentially more effective cancer treatment.

Zhao added that this stem cell-targeting approach can provide an alternative to many forms of chemotherapy, which has a number of bad side effects. While this widely used method is powerful enough to kill rapidly growing cancer cells, it also can harm healthy ones.

Our new type of treatment only targets metastatic tissue, which enables us to avoid some of conventional chemotherapys unwanted side effects, said Zhao, who is a member of the Chao Family Comprehensive Cancer Center and the Sue & Bill Gross Stem Cell Research Center at UCI.

This published work is focused on breast cancer metastases in the lungs, he added. However, the technology will be applicable to other metastases as well, because many solid tumors have the hallmark of being stiffer than normal tissue. This is why our system is innovative and powerful, as we dont have to spend the time to identify and develop a new genetic or protein marker for every kind of cancer.

So far, the Zhao team has done preclinical animal studies to demonstrate that the treatment works and is safe, and they hope to transition to human studies in the near future. They are currently expanding to include other type of cells, including cancer tissue-sensing, engineered immune-system T cells (called CAR-T) to treat metastasizing breast and colon cancers. They also plan to transform the technology for other diseases such as fibrosis and diabetes, which result in stiffening of otherwise healthy tissue.

Along with Zhao, UCI doctoral students Linan Liu and Shirley Zhang, are co-leading authors of the study. The National Institutes of Health, the Department of Defense, the American Cancer Society and the California Institute for Regenerative Medicine provided support.

About the University of California, Irvine: Founded in 1965, UCI is the youngest member of the prestigious Association of American Universities. The campus has produced three Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UCI has more than 30,000 students and offers 192 degree programs. Its located in one of the worlds safest and most economically vibrant communities and is Orange Countys second-largest employer, contributing $5 billion annually to the local economy. For more on UCI, visit http://www.uci.edu.

Media access: Radio programs/stations may, for a fee, use an on-campus ISDN line to interview UCI faculty and experts, subject to availability and university approval. For more UCI news, visit news.uci.edu. Additional resources for journalists may be found at communications.uci.edu/for-journalists.

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UCI stem cell therapy attacks cancer by targeting unique tissue stiffness - UCI News

About Edheads

Edheads is an online educational resource that provides science and math games and activities that promote critical thinking. Choose from Simple Machines, Virtual Knee Surgery or Stem Cell Heart Repair, among others. All activities meet state and national standards.

We partner with corporations, universities, and school systems throughout the United States, which help us research, design, and test our activities every step of the way. Not only do teachers and students appreciate our free activities, Edheads has been recognized by almost every major award on the Web for our excellent educational content.

So search under the "Games" menu at the top of the page to dive into an activity and let the fun and learning begin!

There are still free games on Edheads! Look at the menu bar above, click 'Games' and look for the 'free games' section. You can still play Virtual Hip Resurfacing, Sickle Cell DNA, Trauma and other games without logging on and without a membership!

If you are a teacher purchasing a membership, please remember to set up your sub-accounts, so students can log in!

Important news!To ensure that Edheads can continue to create dynamic, minds-on STEM learning experiences, we are now a membership site. Membership levels and costs can be found here.

Register as a member now!Join the Edheads Community to play all the games you love and help create new ones!

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Posted by admin on November 25, 2014 Leave a Comment

Texans for Stem Cell Research (TSCR), proudly announces its participation in the World Stem Cell Summit, 2014 in San Antonio November 25th, 2014 | Texans for Stem Cell Research (TSCR), proudly announces its participation in the World Stem Cell Summit, 2014 in San Antonio, Texas, December 2-5th, 2014. TSCR will co- host a Welcoming Party for the Genetics Policy Institute, the organizer of the Summit, along with the City of San Antonio and the San Antonio Economic Development Foundation. This event will be held at the San Antonio Convention Center LDR Room, 200 E. Market St. The event will be from 7:30-10:30 pm on December 2, 2014. Featured speakers include Dr. Doris Taylor of the

Posted by admin on February 10, 2014 Leave a Comment

February 9, 2014, 7:00 PM|What 60 Minutes Lesley Stahl learned while reporting on the surprising medical differences between males and females Watch 60 Minutes Overtime Recommend on FacebookTell a friend

Posted by admin on January 23, 2014 Leave a Comment

Scientists have known for years that stem cells in male and female sexual organs are regulated differently by their respective hormones. In a surprising discovery, researchers at the Childrens Medical Center Research Institute at UT Southwestern (CRI) and Baylor College of Medicine have found that stem cells in the blood-forming system which is similar in both sexes also are regulated differently by hormones, with estrogen proving to be an especially prolific promoter of stem cell self-renewal. The research, published in Nature, raises several intriguing possibilities for further investigation that might lead to improved treatments for blood cancers and increased safety and effectiveness of chemotherapy. Before the finding, blood-forming stem cells were thought to

Category Blood, Children, Headlines, Pediatric, Stem Cells, Texas, Texas Research Tags Baylor College of Medicine, blood-forming stem cells, Daisuke Nakada, estrogen, Hideyuki Ogur, hildrens Medical Center Research Institute, hormones, Mary McDermott, pediatric genetics, Sean Morrison, stem cells, UT Southwestern Medical Center

Posted by admin on January 7, 2014 Leave a Comment

Bold New Alliance Among Houstons Leading Health Care Providers to Transform Care Delivery in the Region Clinical Services, Research and Education Greatly Enhanced by New Collaborations for CHI, St. Lukes, Baylor College of Medicine and Texas Heart Institute HOUSTON (Jan. 7, 2014) Three of the regions leading medical institutions Baylor College of Medicine, CHI St. Lukes Health and the Texas Heart Institute have significantly expanded and enhanced their long-standing educational, clinical and research affiliations in conjunction with Englewood, Colo.-based Catholic Health Initiatives, which sponsors and operates the newly named CHI St. Lukes Health. Catholic Health Initiatives, one of the nations largest health systems, announced today that CHI St. Lukes has partnered with Baylor

Posted by admin on November 26, 2013 Leave a Comment

The city of San Antonio will invest $200,000 in a biotech startup founded to develop new advances in stem-cell technology. City Council voted Thursday to invest in StemBioSys, Inc. through a grant to the San Antonio Economic Development Corporation. The money will be used for stem-cell research, development and manufacturing. StemBioSys, founded in 2010, holds two patents and has three others pending. The company has four employees and will hire at least two more in the next year. The company was formed by Dr. Xiao-Dong Chen, a professor at University of Texas Health Science Center at San Antonio, and Dr. Steven Davis, a San Antonio dermatologist, using licensed stem-cell technology Chen created at the university.

Posted by admin on November 19, 2013 Leave a Comment

Research with mice may someday help people recovering from heart attacks, scientists say New insight into the hearts ability to repair itself could help scientists develop ways to improve recovery after a heart attack, a new study of mice suggests. Researchers found that a signaling pathway called the Hippo pathway normally blocks heart repair in adult mice. When certain signals were removed, the animals hearts were able to regenerate after being damaged. This was because specialized heart cells called cardiomyocytes were able to multiply much better after the signals were removed, an ability that is normally lost in damaged hearts, according to the researchers from the Baylor College of Medicine and the Texas

Posted by admin on October 16, 2013 Leave a Comment

Daria O Brians Science Club Adventures in Time Not currently available on BBC iPlayer Series 2 Episode 2 of 6 Dara O Briain and the team go on a journey through time to discover what it is and how to get more of it. Watch Video Recommend on FacebookTell a friend

Category Body Parts, For the Kids!, Organs, Stem Cells, Texas, Texas Research, Videos Tags BBC, Daria O Brian's Science Club, Doris Taylor, For the Kids!, Helen Czerski, organs, Texas Heart Institute

Posted by admin on September 13, 2013 Leave a Comment

HOUSTON Gov. Rick Perry today announced a $3 million investment through the Texas Emerging Technology Fund (TETF) to create the Center for Cell and Organ Biotechnology in collaboration with the Texas Heart Institute (THI) and Texas A&M University College of Veterinary Medicine & Biomedical Sciences. This center represents another step toward making Texas the forefront of biotechnology for generations to come, Gov. Perry said. The investment is all a part of the culture of creation weve nurtured in Texas, built upon the concept that if you give bright and visionary people the freedom to innovate and pursue their dreams, good things will happen. I could not be prouder that this life-affirming research will be

Posted by admin on June 20, 2013 Leave a Comment

Its a pioneering procedure. Doctors at Austins Heart Hospital are taking a patients own stem cells from bone marrow a few days after a heart attack and injecting those stem cells back into formerly blocked arteries. Dr. Roger Gammon is an Interventional Cardiologist who leads the research team at the hospital. He says, We think those stem cells in particular are most able to recover heart muscle and grow new blood vessels in an area which could save that heart muscle. This trial could be a critical next step in fighting the nations number one killer. Medication and surgery to open blocked arteries have dramatically improved survival rates for people with heart disease. But once

Category Headlines, Heart Attacks, Heart Disease, Heart Failure, Stem Cells, Texas, Texas Research, Videos Tags Austin's Heart Hospital, Bone Marrow, heart attack, Roger Gammon, stem cells

Posted by admin on June 19, 2013 Leave a Comment

Texas Heart Institute One of Many Hospitals Seeing Success in Organ Creation On average, 18 people die each day awaiting an organ donation one person is added to the waiting list for organ transplants every ten minutes. Although nearly 80 people receive an organ transplant per day according to OrganDonor.gov, the gap between donations made and those awaiting organs is devastating for those on the waiting list. There is good news on the horizon for the 100,000-plus people awaiting a transplant, however. Researchers in Texas and across the globe are working on a way to create organs from the patients own body. While 3D printed versions of large organs such as kidneys are

Category Headlines, Heart Disease, Stem Cells, Technology, Texas, Texas Research, Videos, World News Tags 3D printed, Doris Taylor, OrganDonor.gov, Stanford, stem cells, Texas Heart Institute

Posted by admin on May 30, 2013 Leave a Comment

Doctors at the Texas Heart Institute (THI) at St. Lukes Episcopal Hospital (SLEH) announced that they have performed an investigational procedure on six patients in a new FDA-approved clinical trial to evaluate therapy that uses regenerative cells derived from a patients own adipose (body fat) tissue to treat a severe form of heart failure. The trial, known as ATHENA, marks the first such study in the United States using adipose-derived regenerative cells, known as ADRCs, which are harvested using a technology developed by Cytori Therapeutics, a biotechnology company that specializes in cell therapies. Previous studies in Europe have shown the safety and feasibility of the therapy. We have found that body fat tissue is a

Category Adipose, Headlines, Heart Disease, Heart Failure, Stem Cells, Technology, Texas, Texas Research Tags adipose, ADRC, Cytori Therapeutics, Fat-Derived Regenerative Cells, heart failure, James T. Willerson, Texas Heart Institute

Posted by admin on April 30, 2013 Leave a Comment

Texas Heart Institute not concerned about changes at St. Lukes A spokesman for Texas Heart Institute said the center does not have any ongoing research that would be in direct conflict with the faith-based medical care of Denver-based Catholic Health Initiatives. The St. Lukes Episcopal Health System said April 19 it decided to sell to CHI, the nations second-largest faith-based health system. Shortly after, concerns arose about whether the Catholic provider would eliminate any procedures currently offered at St. Lukes. The Texas Heart Institute is affiliated with but not owned or governed by St. Lukes, though it is housed within St. Lukes Episcopal Hospital in the Texas Medical Center. CHI issued a statement April 26

Category Headlines, Heart Disease, Heart Failure, Stem Cells, Technology, Texas, Texas Research, Vascular Disease, World News Tags Catholic Health Initiatives, CHI, Denton Cooley, St. Luke's Episcopal Hospital, Texas Heart Institute

Posted by admin on April 25, 2013 Leave a Comment

Latest advances in treatment for Alzheimers,traumatic brain injury and stroke to be presented at symposium AUSTIN, Texas (April 24, 2012) Some of the countrys leading practitioners will discuss the cutting-edge treatments and imaging techniques being developed to treat Alzheimers, traumatic brain injury and stroke at a symposium on May 1 in Austin. Collaborating for Cures: Research, Rehabilitation & Treatment for Alzheimers, Brain Injury & Stroke will feature presentations on The Promise of Stem Cells; Current treatment of closed head injury, Disorders of consciousness, Imaging in dementia, Drug screening for degeneration, Pain syndrome after stoke, Emerging therapeutics in ischemic stroke and Neurorecovery vs neurorehabilitation as well as provide a forum for leading scientists in the

Category Alzheimer's, Headlines, Preclinical, Stroke, Texas, Texas Research Tags Alzheimers, brain injury, CORE Health Care, Core Health Foundation, Moss Rehabilitation & Research Institute, Nantz National Alzheimers Center, NeuroTexas Institute, Reliant Austin Rehabilitation Hospital, Seton Brain & Spine Institute, St. Davids HealthCare, Stroke, Texans for Stem Cell Research, Texas Cures Education Foundation, TIRR Memorial Hermann, UT Southwestern

Posted by admin on March 1, 2013 Leave a Comment

Reprogramming Adult Cells to Stem Cells Works Better with One Gene Turned Off The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell. The discovery six years ago that scientists can convert adult cells into inducible pluripotent stem cells, or iPSCs, bolstered the dream that a patients own cells might be reprogrammed to make patient-specific iPSCs for regenerative medicine, modeling human diseases in petri dishes, and drug screening, said Rongfu Wang, Ph.D., Principal Investigator and Director of the Center for Inflammation and Epigenetics. But reprogramming

Category Drug Discovery, Headlines, Regenerative Medicine, Stem Cells, Texas, Texas Research Tags Center for Inflammation and Epigenetics, drug screening, epigenetic, inducible pluripotent stem cells, Regenerative Medicine, Rongfu Wang, The Methodist Hospital Research Institute

Posted by admin on February 22, 2013 Leave a Comment

A University of Texas spinoff company has pulled in $2 million to test a new technique for culturing non-embryonic stem cells. According to a regulatory filing, StemBioSys raised at least $2 million of a $3.5 million equity offering. A company representative was not available to elaborate, but CEO Dr. Steven Davis told the San Antonio Business Journal last year when the company began raising the round that it would fund research projects to validate the quality of the stem cells generated by the companys technology. StemBioSys is developing XC-marrow ECM, a propriety three-dimensional culture for growing mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord blood. These immature cells have multiple potential uses

Posted by admin on February 7, 2013 Leave a Comment

Every week, it seems, theres a new breakthrough in 3-D printing that promises us the ability to (eventually) fabricate some new thing in one of those glass-walled wonder boxes. Such things have included everything from spare parts for the International Space Station above to the beef on our dinner plates to the organs inside our bodies. Although this last idea of fabricating body parts may seem the most fanciful, a team of scientists is reporting a breakthrough in 3-D printing using human embryonic stem cells that could purportedly lead to life-like bioengineered tissue and, eventually, artificial organs tailor-made for specific patients. Researchers have been able to engineer tissue samples in then past by combining artificial

Posted by admin on January 27, 2013 Leave a Comment

Doris Taylor and her team are building new organs, hoping to reverse disease, maybe even the aging process By Maggie Galehouse | January 23, 2013 It sounds like science fiction, but it is isnt. On the ninth floor of the Texas Heart Institutes Denton Cooley building, Doris Taylor and her team are building human hearts, with help from pigs and stem cells. We think a pig heart is a perfect scaffold for a human heart, based on its structure and size, says Taylor, a passionate scientist with a Ph.D. in pharmacology. One recent morning, a pig heart hung suspended in a clear homemade tank in the lab built for Taylor and her team. Filled with

Category Headlines, Heart Disease, Heart Failure, Regenerative Medicine, Stem Cells, Texas, Texas Research Tags Doris Taylor, Houston Chronicle, Jame T. Willerson, Maggie Galehouse, Regenerative Medicine, stem cells, Texas Heart Insitute

Posted by admin on January 21, 2013 Leave a Comment

After a nationwide competition, Texas Heart Institute at St. Lukes Episcopal Hospital has been chosen as the Biorepository Core Lab for the National Heart, Lung and Blood Institutes network of cardiac stem cell research centers. The seven centers, collectively known as the Cardiovascular Cell Therapy Research Network, are home to a network of physicians, scientists and support staff who work together to study stem-cell therapy for treating heart disease. The goals of the network are to complete research studies that will potentially lead to more effective treatments for patients with cardiovascular disease, and to share knowledge quickly with the health care community. Read Full Story Recommend on FacebookTell a friend

Posted by admin on January 8, 2013 Leave a Comment

Scar Tissue In Damaged Hearts Reprogrammed By Gene Therapy Into Healthy Heart Muscle A cocktail of three specific genes can reprogram cells in the scars caused by heart attacks into functioning muscle cells, and the addition of a gene that stimulates the growth of blood vessels enhances that effect, said researchers from Weill Cornell Medical College, Baylor College of Medicine and Stony Brook University Medical Center in a report that appears online in the Journal of the American Heart Association. The idea of reprogramming scar tissue in the heart into functioning heart muscle was exciting, said Dr. Todd K. Rosengart, chair of the Michael E. DeBakey Department of Surgery at BCM and the reports corresponding

Posted by admin on January 4, 2013 Leave a Comment

The Alliance for Regenerative Medicine (ARM), the international organization representing the interests of the regenerative medicine community, today announced that 18 ARM members will be presenting at the Biotech Showcase 2013 meeting in San Francisco next week. Featuring company presentations by leading organizations in the industry, Biotech Showcase, produced by EBD Group and Demy-Colton Life Science Advisors, has emerged as a high profile forum for mid-, small- and micro-cap and private companies seeking access to the investor community and potential collaborators. Collectively, the ARM members presenting will showcase the wide scope of progress that is taking place in the regenerative medicine and cell therapy field. (Press Release) Recommend on FacebookTell a friend

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Texas Research : Stem Cell Cite

Welcome

The Stem Cell Center Texas Heart Institute is dedicated to the study of adult stem cells and their role in treating diseases of the heart and the circulatory system. Through numerous clinical and preclinical studies, we have come to realize the potential of stem cells to help patients suffering from cardiovascular disease.We are actively enrolling patients in studies using stem cells for the treatment of heart failure, heart attacks, and peripheral vascular disease.

Whether you are a patient looking for information regarding our research, or a doctor hoping to learn more about stem cell therapy, we welcome you to the Stem Cell Center. Please visit our Clinical Trials page for more information about our current trials.

Emerson C. Perin, MD, PhD, FACC Director, Clinical Research for Cardiovascular Medicine Medical Director, Stem Cell Center McNair Scholar

You may contact us at:

E-mail: stemcell@texasheart.org Toll free: 1-866-924-STEM (7836) Phone: 832-355-9405 Fax: 832-355-9440

We are a network of physicians, scientists, and support staff dedicatedto studying stem cell therapy for treating heart disease. Thegoals of the Network are to complete research studies that will potentially lead to more effective treatments for patients with cardiovasculardisease, and to share knowledge quickly with the healthcare community.

Websitein Spanish (En espaol)

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The Stem Cell Center at Texas Heart Institute

OMICS International Conferences invites all the participants from all over the world to attend '6th World Congress on Cell & Stem Cell Research during February 29-March 02, 2016 in Philadelphia, USA which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions

Track01:Stem Cell

The most well-established and widely used stem cell treatment is thetransplantationof blood stem cells to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers. Since the 1970s,skin stem cellshave been used to grow skin grafts for patients with severe burns on very large areas of the body. Only a few clinical centers are able to carry out this treatment and it is usually reserved for patients with life-threatening burns. It is also not a perfect solution: the new skin has no hair follicles or sweat glands. Research aimed at improving the technique is ongoing.

Related Conferences:

International Conference on Pancreatic andColorectal Cancer, March 29-30, 2016, Atlanta, USA; International Conference onProstate Cancerand Treatment, May 5-7, 2016, Chicago, USA;Cancer DiagnosticsConference & Expo, June 13-15, 2016, Rome, Italy; International Conference onTissue Scienceand Regenerative Medicine, Sept 12-14, 2016, Berlin Germany;Gene Regulatory Networks and the Encoded Causality of Development, May 16-18, 2016, California, USA; Stem Cell Models of Neural Degeneration and Disease, February 1-3, 2016 Dresden, Germany;Stem Cellsand Cancer, March 6-10, 2016, Colorado, USA; Transdifferentiation and Tissue Plasticity inCardiovascular Rejuvenation; February 7-10, 2016, West Sussex, UKTrack 01:Cell Differentiation:

Cellular differentiation is the progression, whereas a cell changes from one cell type to another. Variation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.

Related Conferences:

5th International Conference and Exhibition on Cell & Gene Therapy, May 19-21, 2016,San Antonio, USAInternational Conference on Melanoma and Carcinoma, July 14-15, 2016,Brisbane, Australia,Annual Conference Stem Cell and Regenerative on Medicine, Aug 4-6, 2016, Frankfurt, Germany; 9th International Conference on Molecular & Cellular Cardiology, Aug 22-24, 2016, Sao Paulo, Brazil;4th International Conference on Blood Malignancies and Treatment,April 18-20, 2016,Dubai, UAE; 2ndInternational Congress onNeuroimmunology& Therapeutics, March 31-Apr 2, 2016, Atlanta, USA; Molecular and Cellular Basis of Growth and Regeneration, January 10-14, 2016 , Colorado, USA; Phacilitate Cell & Gene Therapy World, January 25-27, Washington D.C., USA; ISSCR Stem Cell Models of Neural Degeneration and Disease, 1-3 February 2016, Dresden, Germany; Craniofacial Morphogenesis & Tissue Regeneration, March 13-18, 2016, California, USA; Keystone Stem Cells and Cancer, March 6-10, 2016 Colorado, USA

Track02:Cell Metabolism:

Metabolism is the set of life-nourishing chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids.

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International Conference on Tissue Science and Regenerative Medicine, Sept 12-14, 2016, Berlin Germany; International Conference on Pancreatic and Colorectal Cancer, March 29-30, 2016, Atlanta, USA; International Conference on Prostate Cancer and Treatment, May 5-7, 2016, Chicago, USA; Cancer Diagnostics Conference & Expo, June 13-15, 2016, Rome, Italy; International Conference Bimolecular Engineering, January 5-7, 2016, Singapore; Molecular and Cellular Basis of Growth and Regeneration, January 10-14, 2016, Colorado, USA; Metabolism, Transcription and Disease, January 10-14, 2016, Iquitos, Peru; Gordon Research Conference & Seminar "Origins of Life", January 17-22, 2016, Galveston, USA; Small RNA Silencing Little Guides, Big Biology, January 24-28, 2016, Colorado, USA

Track03:Tissue Engineering:

Tissue Engineering is the study of the growth of new connective tissues, or organs, from cells and a collagenous scaffold to produce a fully functional organ for implantation back into the donor host. Powerful developments in the multidisciplinary field of tissue engineering have produced a novel set of tissue replacement parts and implementation approaches. Scientific advances in biomaterials, stem cells, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabricate tissues in the laboratory from combinations of engineered extracellular matrices cells, and biologically active molecules.

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Experts Meeting on Gynecologic Oncology, May 19-21, 2016 San Antonio, USA; Annual Plant Genomics Conference, July 14-15, 2016, Brisbane, Australia; International Conference on Integrative Biology, July 18-20, 2016, Berlin, Germany; Industrial Biotechnology Congress, July 28-29, 2016, Berlin, Germany; Asia Pacific Biotech Congress, July 25-27, 2016, Bangkok, Thailand; International Conference on Tissue Engineering and Regenerative Medicine, June 9-10, 2016, San Francisco, USA; Keystone Stem Cells and Regeneration in the Digestive Organs, March 13-17, 2016 Colorado, USA; ISSCR Pluripotency: From basic science to therapeutic applications, 22-24, March 2016 Kyoto, Japan; Keystone Cardiac Development, Regeneration and Repair, April 3-7, 2016 Utah, USA; The Stem Cell NicheDevelopment & Disease, 22-26, May 2016, Hillerd, Denmark

Track04:Epigenetics:

Epigenetics is the study of genetics, cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence. Epigenetic change in eukaryotic biology is the process of cellular differentiation. During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells.

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International Conference on Cancer Genomics, Aug 8-9, 2016, Las Vegas, USA; International Conference on Genetics Counseling and Genomics Medicine, Aug 11-12, 2016, Birmingham, UK; Biotechnology World Convention, Aug 15-17, 2016, Sao Paulo, Brazil; International Conference on Synthetic Biology, Aug 18-19, 2016, London, UK, Annual Conference on Bio Science, Sept 12-13, 2016, Berlin, Germany; Noncoding RNAs in Health and Disease, February 21-24, 2016, Santa Fe, USA; Maintenance of Genome Stability March 7- 10, 2016, Panama, South America; Chromatin and Epigenetics, March 20-24, 2016 Whistler, Canada; Chromatin, Non-Coding RNAs and RNAP II Regulation in Development and Disease, March 29, 2016, Austin, USA; Chromatin Structure & Function, May 22-27, 2016, Les Diablerets, Switzerland

Track05:Gene Therapy:

Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.

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5thWorld Congress on Hemophilia, June 6-8, 2016, London, UK; 2nd World Bio Summit & Expo, Oct 13-15, 2016, Dubai, UAE; 4th International Conference on Genomics & Pharmacogenomics, Sept 12-14, 2016, Berlin Germany; International Conference on Molecular Biology, Oct 13-15, 2016, Dubai, UAE; World Congress on Human Genetics, Oct 31 - Nov 2, 2016, Valencia, Spain; International Conference on Cell and Gene Therapy, March 3-4, 2016, Singapore; Molecular and Cellular Basis of Growth and Regeneration, January 10-14, 2016, Colorado, USA; Axons: from cell biology to pathology, January 24-27, 2016, New Mexico; Craniofacial Morphogenesis & Tissue Regeneration, March 13-18, 2016, California, USA

Track07:Cell Biology of Aging:

Aging process is the result of the inability of various types of stem cells to continue to replenish the tissues of an organism with functional differentiated cells capable of maintaining that tissues (or organ's) original function.

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International Conference on Cancer Genomics, Aug 8-9, 2016, Las Vegas, USA; International Conference on Genetics Counseling and Genomics Medicine, Aug 11-12, 2016, Birmingham, UK; Biotechnology World Convention, Aug 15-17, 2016, Sao Paulo, Brazil;International Conference on Medical Ethics and Health Policies, June 9-11, 2016, London, UK, Annual Conference on Bio Science, Sept 12-13, 2016, Berlin, Germany; International Aging and Disease Conference, October 01-02, 2016, Stanford, USA; 4th World Parkinson Congress, September 5-6, 2016 Portland, USA; Disasters in an Ageing World-Readiness, Resilience and Recovery, June 21-23, 2016, Brisbane, Australia; American Geriatrics Society Annual Scientific Meeting, May 19-21, 2016, Long Beach, USA; American Society on Aging (ASA) 2016 Aging in America Conference, March 20-24, 2016, Washington, USA

Track08:Computational Biology:

Computational Biology, sometimes referred to as bioinformatics, is the science of using biological data to develop algorithms and relations among various biological systems. Bioinformatics groups use computational methods to explore the molecular mechanisms underpinning stem cells. To accomplish this bioinformatics develop and apply advanced analysis techniques that make it possible to dissect complex collections of data from a wide range of technologies and sources.

The fields of stem cell biology and regenerative medicine research are fundamentally about understanding dynamic cellular processes such as development, reprogramming, repair, differentiation and the loss, acquisition or maintenance of pluripotency. In order to precisely decipher these processes at a molecular level, it is critical to identify and study key regulatory genes and transcriptional circuits. Modern high-throughput molecular profiling technologies provide a powerful approach to addressing these questions as they allow the profiling of tens of thousands of gene products in a single experiment. Whereas bioinformatics is used to interpret the information produced by such technologies.

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6thInternational Conference on Bioinformatics, March 29-30, 2016 Valencia, Spain;6th International Conference and Expo on Proteomics, March 29-31, 2016, Atlanta, USA; 4th International Conference on Integrative Biology, July 18-20, 2016, Berlin, Germany; Industrial Biotechnology Congress, July 28-29, 2016, Berlin, Germany; Asia Pacific Biotech Congress, July 25-27, 2016, Bangkok, Thailand; International Conference on Computational Biology, Paris, France; February 22-23, 2016 Systems Immunology: From Molecular Networks to Human Biology, January 10-14, 2016 Montana, United States; Whole-Cell Modeling Summer School, April 3-8, 2016 Barcelona, Spain; From Functional Genomics to Systems Biology, November 12-15, 2016, Heidelberg, Germany

Track09:Genetic Engineering:

Genetic engineering is the direct manipulation of an organism's genome using biotechnology. Whereas set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism.

Embryonic stem cells have a major potential for studying early steps of development and for use in cell therapy. In many situations, however, it will be necessary to genetically engineer these cells. A novel generation of lentivectors which permit easy genetic engineering of mouse and human embryonic stem cells.

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Annual Plant Genomics Conference, July 14-15, 2016, Brisbane, Australia; 4th International Conference on Integrative Biology, July 18-20, 2016, Berlin, Germany; Industrial Biotechnology Congress, July 28-29, 2016, Berlin, Germany; Asia Pacific Biotech Congress, July 25-27, 2016, Bangkok, Thailand; 5thInternational Conference and Exhibition on Cell andGene Therapy, May 19-21, 2016 San Antonio, USA; International Conference Biomolecular Engineering, Singapore; Cell Culture 2016, London, UK; 4thBiotechnology World Congress, Dubai, UAE; Genome Editing and Gene Modulation Congress 2016, Oxford, UK; European Symposium on Biochemical Engineering Sciences 2016, Dublin, Ireland

Track10:Apoptosis:

Apoptosis is the process of programmed cell death (PCD) that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Most cytotoxic anticancer agents induce apoptosis, raising the intriguing possibility that defects in apoptotic programs contribute to treatment failure. Because the same mutations that suppress apoptosis during tumor development also reduce treatment sensitivity, apoptosis provides a conceptual framework to link cancer genetics with cancer therapy.

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14th World Congress on Cancer Therapy, Dec 8-10, 2016, Dallas, USA; 13th Global Oncologists Summit and Cancer Therapy, Oct 17-19, 2016, Dubai, UAE; 12th Euro Global Summit on Cancer Therapy, Sept 26-28, 2016, London, UK; International Conference on Cervical Cancer, Sept 22-23, 2016, Vienna, Austria; 2nd World Congress on Breast Cancer, Sept 19-21, 2016, Pheonix, USA; Cell Death, July 3-8, 2016 Girona, Spain; A Matter of Life or Death: Cell Death in Cancer, January 28 -30, 2016 Amsterdam, Netherlands; Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, March 6-10, 2016 Whistler, Canada; Symposium on Signalling Pathways in Cancer 2016: Focusing on the HER/EGFR family signalling, March 04-05, 2016, Barcelona, Spain

Track11:Somatic Cell Therapy:

Somatic cell therapy is the administration to humans of autologous, allogeneic, or xenogeneic living cells which have been manipulated or processed ex vivo. Manufacture of products for somatic cell therapy involves the ex vivo propagation, expansion, selection. Somatic cell therapy is viewed as a more conservative, safer approach because it affects only the targeted cells in the patient, and is not passed on to future generations. Somatic gene therapy represents mainstream basic and clinical research, in which therapeutic DNA (either integrated in the genome or as an external episome or plasmid) is used to treat disease. Most focus on severe genetic disorders, including immunodeficiencies, haemophilia, thalassaemia and cystic fibrosis. Such single gene disorders are good candidates for somatic cell therapy.

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2nd International Conference on Antimicrobial Agents and Chemotherapy, June 6-7, 2016 Dallas, USA;9th Global Diabetelogists Annual Meeting and Medicare Expo, June 6-8, 2016, Dallas, USA; 4th International Conference on Integrative Biology, July 18-20, 2016, Berlin, Germany; Industrial Biotechnology Congress, July 28-29, 2016, Berlin, Germany; Asia Pacific Biotech Congress, July 25-27, 2016, Bangkok, Thailand; International Conference Biomolecular Engineering, Singapore; Cell Culture 2016, London, UK; Reprogramming Cell Fate, March 04-05, 2016, Texas, USA; International Conference on Cell and Gene Therapy, July 25-26, 2016 Paris, France; Derivation and Culture of Human Induced Pluripotent Stem Cells, Hinxton, UK; Axons: from cell biology to pathology, New Mexico; Annual Meeting of the Japan Society of Gene Therapy (JSGT), October 18 -21, 2016, Japan

Track12:Histology of Cell biology:

Histology is the scientific study of biological tissues. It is the microscopic study of the structure of biological tissues using special staining techniques combined with light and electron microscopy. Histology is the study of the microscopic structures of cells and tissues of plants and animals. Histological studies may be conducted using tissue culture, where live human or animal cells are isolated and maintained in an artificial environment for various research projects. The ability to visualize microscopic structures is frequently enhanced through the use of histological stains. Histology is an essential tool of biology and medicine.

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Annual Plant Genomics Conference, July 14-15, 2016, Brisbane, Australia; 4th International Conference on Integrative Biology, July 18-20, 2016, Berlin, Germany; Industrial Biotechnology Congress, July 28-29, 2016, Berlin, Germany; Asia Pacific Biotech Congress, July 25-27, 2016, Bangkok, Thailand; 5thInternational Conference and Exhibition on Cell andGene Therapy, May 19-21, 2016 San Antonio, USA; International Conference Biomolecular Engineering, Singapore; Cell Culture 2016, London, UK; United States & Canadian Academy of Pathology Annual Meeting, March 12-18, 2016, Seattle, USA; ISSCR Stem Cell Models of Neural Degeneration and Disease, February 1-3, 2016, Dresden, Germany; Craniofacial Morphogenesis & Tissue Regeneration, March 13-18, 2016, California, USA; Keystone Stem Cells and Cancer, March 6-10, 2016, Colorado, USA

Track13:Human Embryology:

Human embryogenesis is the process of cell division and cellular differentiation of the embryo that occurs during the early stages of development. Whereas human development entails growth from a stage celled zygote to an adult human being stage. Fertilization occurs when the sperm cell successfully enters and fuses with an egg cell (ovum). The genetic material of the sperm and egg then combine to form a single cell called a zygote and the germinal stage of prenatal development commences.

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Annual Conference Stem Cell and Regenerative on Medicine, Aug 4-6, 2016, Frankfurt, Germany; 9th International Conference on Molecular & Cellular Cardiology, Aug 22-24, 2016, Sao Paulo, Brazil; 2nd International Conference and Exhibition on Tissue preservation and Bio-banking, Aug 18-19, 2016, Portland, Oregon; International Conference on Human Reproduction and Embryology, May 23-24, 2016, London, UK; Conference on Embryology and Developmental Biology, June 1-3, 2016, Nanjing, China; European Society of Human Reproduction and Embryology, July 3-6, 2016, Helsinki, Finland

Track14:Tumour Cell Science:

An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant. Tomour usually reflect the kind of tissue they arise in. Treatment is also specific to the location and type of the tumor. Benign tumors can sometimes simply be ignored, cancerous tumors; options include chemotherapy, radiation, and surgery.

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International Conference onCancer Genomics, Aug 8-9, 2016, Las Vegas, USA; International Conference on Genetics Counseling andGenomics Medicine, Aug 11-12, 2016, Birmingham, UK; Biotechnology World Convention, Aug 15-17, 2016, Sao Paulo, Brazil; International Conference onSynthetic Biology, Aug 18-19, 2016, London, UK, Annual Conference onBio Science, Sept 12-13, 2016, Berlin, Germany; Pediatric Oncology Conference, January 20-21, 2016, Brussels, Belgium; Progress and Controversies in Gynecologic Oncology Conference, January 22-23, 2016, Barcelona, Spain; Cancer Immunotherapy Immunity and Immunosuppression Meet Targeted Therapies, January 24-28, 2016, British Columbia, Canada; The Cancer Genome, February 7-11, 2016 Banff, Canada

Track15:Stem Cell Biomarkers:

Molecular biomarkers serve as valuable tools to classify and isolate embryonic stem cells (ESCs) and to monitor their differentiation state by antibody-based techniques. ESCs can give rise to any adult cell type and thus offer enormous potential for regenerative medicine and drug discovery. A number of biomarkers, such as certain cell surface antigens, are used to assign pluripotent ESCs; however, accumulating evidence suggests that ESCs are heterogeneous in morphology, phenotype and function, thereby classified into subpopulations characterized by multiple sets of molecular biomarkers.

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International Conference and Exhibition on Cell & Gene Therapy, May 19-21, 2016, San Antonio, USA; Annual Conference Stem Cell and Regenerative on Medicine, Aug 4-6, 2016, Frankfurt, Germany; 9th International Conference on Molecular & Cellular Cardiology, Aug 22-24, 2016, Sao Paulo, Brazil; 2nd International Conference and Exhibition on Tissue preservation and Bio-banking, Aug 18-19, 2016, Portland, Oregon; Stem Cell Research & Regenerative Medicine Conference, April 25-26, 2016, Boston, USA; International Conference on Cell and Stem Cell Engineering, September 15 - 16, 2016, Rome, Italy; International Conference on Stem Cells & Regenerative Medicine, December 17-18, 2016, Bangkok, Thailand; Molecular and Cellular Basis of Growth and Regeneration Breckenridge, January 10-14, 2016, Colorado, USA; Tissue Niches & Resident Stem Cells in Adult Epithelia, August 7-12, Hong Kong, China

Track16:Stem Cell Therapy:

Autologous cells are obtained from one's own body, just as one may bank his or her own blood for elective surgical procedures. Adult stem cells are frequently used in medical therapies, for example in bone marrow transplantation. Human embryonic stem cells may be grown in vivo and stimulated to produce pancreatic -cells and later transplanted to the patient. Its success depends on response of the patients immune system and ability of the transplanted cells to proliferate, differentiate and integrate with the target tissue.

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9thInternational Conference on Molecular & CellularCardiology, Aug 22-24, 2016, Sao Paulo, Brazil;International Conference and Exhibition on Cell & Gene Therapy, May 19-21, 2016, San Antonio, USA; Annual Conference Stem Cell and Regenerative on Medicine, Aug 4-6, 2016, Frankfurt, Germany;2nd International Conference and Exhibition on Tissue preservation and Bio-banking, Aug 18-19, 2016, Portland, Oregon; Phacilitate Cell & Gene Therapy World, January 25-27, 2016, Washington D.C, USA; International Conference on Nucleic Acids, January 7-8, 2016, Singapore; 5th Zing Nucleic Acids Conference, December 2-5, 2016 Tampa, Florida; Germline Stem Cells Conference, , June 19-21, 2016, San Francisco, USA; Notch Signaling in Development, Regeneration & Disease Gordon Research Conference, July 31-August 5, 2016, Lewiston, USA

Track17:Novel Stem Cell Technologies:

Stem cell technology is a rapidly developing field that combines the efforts of cell biologists, geneticists, and clinicians and offers hope of effective treatment for a variety of malignant and non-malignant diseases. Stem cells are defined as totipotent progenitor cells capable of self-renewal and multilineage differentiation. Stem cells survive well and show stable division in culture, making them ideal targets for in vitro manipulation. Although early research has focused on haematopoietic stem cells, stem cells have also been recognised in other sites. Research into solid tissue stem cells has not made the same progress as that on haematopoietic stem cells.

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Cancer Diagnostics Conference & Expo, June 13-15, 2016, Rome, Italy; 9th International Conference on Molecular & Cellular Cardiology, Aug 22-24, 2016, Sao Paulo, Brazil; 2nd International Conference and Exhibition on Tissue preservation and Bio-banking, Aug 18-19, 2016, Portland, Oregon; Molecular and Cellular Basis of Growth and Regeneration Breckenridge, January 10-14, 2016, Colorado, USA; Derivation and Culture of Human Induced Pluripotent Stem Cells, Hinxton, UK; Challenges, Solutions and Progress in Stem Cell Medicine, 18-21 February, 2017 San Diego, USA; EMBL Hematopoietic Stem Cells: From the Embryo to the Aging Organism, June 3-5, 2016, Heidelberg, Germany

Track 18:Cancer Biology:

Cancer can be defined as a disease in which a group of abnormal cells grow uncontrollably by disregarding the normal rules of cell division. Normal cells are constantly subject to signals that dictate whether the cells should divide, differentiate into another cell or die. Cancer cells develop a degree of anatomy from these signals, resulting in uncontrolled growth and proliferation. If this proliferation is allowed to continue and spread, it can be fatal.

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14th World Congress on Cancer Therapy, Dec 8-10, 2016, Dallas, USA; 13th Global Oncologists Summit and Cancer Therapy, Oct 17-19, 2016, Dubai, UAE; 12th Euro Global Summit on Cancer Therapy, Sept 26-28, 2016, London, UK; International Conference on Cervical Cancer, Sept 22-23, 2016, Vienna, Austria; 2nd World Congress on Breast Cancer, Sept 19-21, 2016, Pheonix, USA; ESMO Sarcoma & GIST Conference 2016, 16-17 February, 2016 Milan, Italy; ESMO Symposium on Signalling Pathways in Cancer 2016: Focusing on the HER/EGFR family signalling, March 4-5, 2016, Barcelona, Spain; European Lung Cancer Conference, April 13-16, 2016, Geneva, IMPAKT 2016 Breast Cancer Conference, May 12-14, 2016, Brussels, Belgium; World Congress on Gastrointestinal Cancer 2016, 29-02 July, 2016, Barcelona, Spain

Stem Cell Research is an international forum to present and discuss current perspectives in cell and stem cell research. Stem Cell Research is the unified study of the properties of cells and living organisms and all aspects of their interactions. Stem Cell Research has the goal to fulfill the prevailing gaps in the transformation of this science of hope, to serve promptly with solutions to all in the need.

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5th International Conference and Exhibition on Cell & Gene Therapy, May 19-21, 2016, San Antonio, USA; Annual Conference Stem Cell and Regenerative on Medicine, Aug 4-6, 2016, Frankfurt, Germany; 9th International Conference on Molecular & Cellular Cardiology, Aug 22-24, 2016, Sao Paulo, Brazil; 2nd International Conference and Exhibition on Tissue preservation and Bio-banking, Aug 18-19, 2016, Portland, Oregon; Molecular and Cellular Basis of Growth and Regeneration, January 10-14, 2016 , Colorado, USA; Phacilitate Cell & Gene Therapy World, January 25-27, Washington D.C., USA; ISSCR Stem Cell Models of Neural Degeneration and Disease, 1-3 February 2016, Dresden, Germany; Craniofacial Morphogenesis & Tissue Regeneration, March 13-18, 2016, California, USA; Keystone Stem Cells and Cancer, March 6-10, 2016 Colorado, USA

6th World Congress on Cell & Stem Cell Research

The success of the 5thCell Science conference series has given us the prospect to bring the gathering one more time for our 6thWorld Congress 2016 meet in Philadelphia, USA. Since its commencement in 2011 cell science series has perceived around 500 researchers of great potentials and outstanding research presentations around the globe. The awareness of stem cells and its application is increasing among the general population that also in parallel offers hope and add woes to the researchers of cell science due to the potential limitations experienced in the real-time.

Stem Cell Research-2016has the goal to fill the prevailing gaps in the transformation of this science of hope to promptly serve solutions to all in the need.World Congress 2016 will have an anticipated participation of 150-200 delegates from around the world to discuss the conference goal.

History of Stem cells Research

Stem cells have an interesting history, in the mid-1800s it was revealed that cells were basically the building blocks of life and that some cells had the ability to produce other cells. Efforts were made to fertilize mammalian eggs outside of the human body and in the early 1900s, it was discovered that some cells had the capacity to generate blood cells. In 1968, the first bone marrow transplant was achieved successfully to treat two siblings with severe combined immunodeficiency. Other significant events in stem cell research include:

1978: Stem cells were discovered in human cord blood 1981: First in vitro stem cell line developed from mice 1988: Embryonic stem cell lines created from a hamster 1995: First embryonic stem cell line derived from a primate 1997: Cloned lamb from stem cells 1997: Leukaemia origin found as haematopoietic stem cell, indicating possible proof of cancer stem cells

Funding in USA:

No federal law forever did embargo stem cell research in the United States, but only placed restrictions on funding and use, under Congress's power to spend. By executive order on March 9, 2009, President Barack Obama removed certain restrictions on federal funding for research involving new lines of humanembryonic stem cells. Prior to President Obama's executive order, federal funding was limited to non-embryonic stem cell research and embryonic stem cell research based uponembryonic stem celllines in existence prior to August 9, 2001. In 2011, a United States District Court "threw out a lawsuit that challenged the use of federal funds for embryonic stem cell research.

Members Associated with Stem Cell Research:

Discussion on Development, Regeneration, and Stem Cell Biology takes an interdisciplinary approach to understanding the fundamental question of how a single cell, the fertilized egg, ultimately produces a complex fully patterned adult organism, as well as the intimately related question of how adult structures regenerate. Stem cells play critical roles both during embryonic development and in later renewal and repair. More than 65 faculties in Philadelphia from both basic science and clinical departments in the Division of Biological Sciences belong to Development, Regeneration, and Stem Cell Biology. Their research uses traditional model species including nematode worms, fruit-flies, Arabidopsis, zebrafish, amphibians, chick and mouse as well as non-traditional model systems such as lampreys and cephalopods. Areas of research focus include stem cell biology, regeneration, developmental genetics, and cellular basis of development, developmental neurobiology, and evo-devo (Evolutionary developmental biology).

Stem Cell Market Value:

Worldwide many companies are developing and marketing specialized cell culture media, cell separation products, instruments and other reagents for life sciences research. We are providing a unique platform for the discussions between academia and business.

Global Tissue Engineering & Cell Therapy Market, By Region, 2009 2018

$Million

Figure 1:Market by Geography

Why to attend???

Stem Cell Research-2016 could be an outstanding event that brings along a novel and International mixture of researchers, doctors, leading universities and stem cell analysis establishments creating the conference an ideal platform to share knowledge, adoptive collaborations across trade and world, and assess rising technologies across the world. World-renowned speakers, the most recent techniques, tactics, and the newest updates in cell science fields are assurances of this conference.

A Unique Opportunity for Advertisers and Sponsors at this International event:

http://stemcell.omicsgroup.com/sponsors.php

UAS Major Universities which deals with Stem Cell Research

University of Washington/Hutchinson Cancer Center

Original post:
Cell and Stem Cell Conferences | Exhibitions | Worldwide ...

This is the amount we raised due all of you!

Thank you to all of our sponsors, musicians golfers, cooks, volunteers, and everyone else that helped make our "Swingin' n' Singin' for Cures" an incredible event.

We have a goal of raising another $78,000 by October 31st, 2014.

So please help spread the word and tell your friends to please hit the Donate button here on our home page and let's get to this goal!

These funds will go directly to the groundbreaking research of Dr. Will Decker and Ratan Bhardwaj, two members of our Medical Advisory Committee. Please read their executive summary link on this page to learn how their t-cell immunology to treat tumors may make chemo and radiation treatments a thing of the past!

Also TSCR will be represented at this year's World Stem Cell Summit in San Antonio, December 3-5th. TSCR's Chairman, David L. Bales has been asked to speak on grass roots stem cell advocacy.

We are honored to be able to speak on behalf of all Texans that support stem cell research and regenerative medicine.

The rest is here:
Texans for Stem Cell Research

The following locations are currently performing research or trials in Texas.

Texas A&M University Mesenchymal Stem Cell Distribution Prepares and distributes well-characterized marrow stromal cells (MSCs) derived from adult human and rodent bone marrow using standardized protocols.

Texas Heart Institute Stem Cell Center Dedicated to the study of adult stem cells and their role in treating cardiovascular disease, including clinical trials (in human patients), as well as many preclinical studies (in the laboratory) using stem cells.

ClinicalTrial.gov A registry of federally and privately supported clinical trials conducted in the United States and around the world. ClinicalTrials.gov gives you information about a trial's purpose, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals.

ClinicalTrials at MDAndersonCancer Center The Houston, Texas based Cancer Center is involved in many exiciting trials.

Institute for RegenerativeMedicine The goal of the IRM is to bridge the gap between basic science and clinical translation in the field of regenerative medicine and experimental cell therapeutics. Through active collaboration between basic scientists and clinicians in Central Texas, the IRM hopes to tackle the ambitious task of discovering novel therapies for intractable diseases to relieve human suffering.

Read more:
Does Texas Have Research Now? | Texans for Stem Cell Research