Category Archives: Stem Cell Therapy

(Image: Charles Vacanti and Koji Kojima, Harvard Medical School)

Talk about speedy work. Hot on the heels of the news that simply dipping adult mouse cells in acid could turn them into cells with the potential to turn into any cell in the body, it appears that the same thing may have been done using human cells.

The picture above, given to New Scientist by Charles Vacanti at Harvard Medical School, is said to be images of the first human "STAP cell" experiments.

Last week, the scientific world was bowled over by a study in Nature showing that an acidic environment turned adult mouse cells into "totipotent" stem cells which can turn into any cell in the body or placenta. The researchers called these new totipotent cells stimulus-triggered acquisition of pluripotency (STAP) cells.

"If they can do this in human cells, it changes everything," Rob Lanza of Advanced Cell Technologies in Marlborough, Massachusetts, said at the time. The technique promises cheaper, quicker and potentially more flexible cells for regenerative medicine, cancer therapy and cloning.

Now, Vacanti and his colleagues say they have taken human fibroblast cells and tested several environmental stressors on them in an attempt to recreate human STAP cells. He won't reveal what type of stressors were applied but he says the resulting cells appears similar in form to the mouse STAP cells. His team is in the process of testing to see just how stem-cell-like these cells are.

Vacanti says that the human cells took about a week to resemble STAP cells, and formed spherical clusters just like their mouse counterparts. Using a similar experimental set-up with green monkey (Chlorocebus sabaeus) cells, Vacanti says the resulting cells are behaving slightly differently. He says that may be due to the fact that the researchers used slightly different techniques. Both Vacanti and his Harvard colleague Koji Kojima emphasise that these results are only preliminary and much further analysis and validation is required.

"Even if these are STAP cells they may not necessarily have the same potential as mouse ones they may not have the totipotency which is one of the most interesting features of the mouse cells," says Sally Cowley, head of the James Martin Stem Cell Facility at the University of Oxford.

Pluripotent cells, such as embryonic stem cells, can form any cell in an embryo but not a placenta. Totipotent cells, however, can form any cell in an embryo and a placenta meaning they have the potential to create life. The only cells known to be naturally totipotent are in embryos that have only undergone the first couple of cell divisions immediately after fertilisation.

Research using totipotent cells would have to be under very strict regulatory surveillance, says Cowley. "It would actually be ideal if the human cells could be pluripotent and not totipotent it would make everyone's life a lot easier."

Continued here:
Extraordinary stem cell method tested in human tissue

Las Vegas, NV (PRWEB) February 05, 2014

Global Stem Cells Group, Inc. and affiliate Stem Cell Training, Inc. were represented by Josepth Purita, M.D. at the 21st Annual World Congress on Anti-Aging, Regenerative and Aesthetic Medicine in Las Vegas, Dec. 15, 2013. Purita, a lead trainer for Stem Cell Training, Inc. and a pioneer in the use of stem cell therapies in orthopedics, addressed more than 5,000 conference attendees with his presentation titled, Cutting Edge Concepts for the Regenerative Medicine Physician in the Use of Stem Cell & PRP Injections.

The record number of attendees gathered from around the world at the Venetian/Palazzo Resort in Las Vegas for three days to attend the prestigious conference hosted by the American Academy of Anti-aging Medicine. The conference featured physicians and medical personnel who practice and manage stem cell technology, certification, and pellet therapy to discuss brain health and offer case studies. Workshops on personalized lifestyle medicine and aesthetic medicine were also held.

Purita was joined by an illustrious group of speakers including: Author Judith Reichman, M.D., womens health care expert and specialist in gynecology, infertility and menopause; Travis Stork, M.D., ER physician and host of the Emmy Award-winning talk show, The Doctors; and Actress and Author Suzanne Somers, a dedicated health advocate and proponent of alternative and integrative medicine.

Former California Gov. Arnold Schwarzenegger accepted the 2013 A4M Infinity Award at Saturday afternoons general session for his progressive leadership role in early funding and support of stem cell research and healthcare reform. Somers presentation Our Time Has Come, discussing the medical needs of the rapidly aging baby-boom population. Stork, host of the Emmy-Award-winning medical talk show The Doctors, discussed long-term health in a speech called Your Best Life. Reichmans presentation titled Slow Your Clock Down: On- Label, Off- Label, Gray- Label, discussed the importance on maintain balance and living a healthy lifestyle.

For more information on the World Congress on Anti-Aging, Regenerative and Aesthetic Medicine, plus upcoming conferences and training programs around the world, visit the A4M website, email, bnovas(at)regenestem(dot)com or call 849.943.2988.

About the Global Stem Cell Group:

Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.

Global Stem Cells Groups corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCGs six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.

The Global Stem Cell Foundation was formed as a nonprofit charitable organization that aims to fund research on the expanding need for stem cell solutions for patients, and identify best practices between physicians engaged in stem cell treatments in the U.S. and around the world.

Excerpt from:
Joseph Purita, M.D. of Global Stem Cells Group, Inc. Featured Speaker at 21st Annual World Congress on Anti-Aging ...

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Stem cell research is on the rise, giving hope to patients and providing treatment for many diseases and disorders. While stem cell treatments are a fairly new science, they can have life-saving effects.

Stem cell treatments consist of removing healthy regenerative cells from the patient and transplanting them into the affected area. This treatment helps repair and reverse a variety of conditions and diseases.

Regenerative cells can be harvested from the patient's bone marrow, fat or peripheral blood. This is done to eliminate the risk of cell rejection in the patient.

Typically, four to six treatments are administered depending on how the condition reacts to the stem cell treatment. Treatments are given over a period of seven to 12 days.

Stem cell treatments are effective at treating autoimmune diseases, cerebral palsy, degenerative joint disease, multiple sclerosis, osteoarthritis, rheumatoid arthritis, spinal injuries and type 2 diabetes. It is thought that in the future, stem cell treatment can be used to treat Alzheimer's disease.

Stem cell therapy can reduce pain and discomfort; it can help patients suffering from arthritis regain mobility. In serious cases, such as cerebral palsy and multiple sclerosis, stem cell treatments can be life-saving.

Because stem cell treatment is a new science, little is known about its long term effects. According to Cell Medicine, no side effects have been reported by patients other than pain at the injection site.

See the article here:
What Is Stem Cell Treatment? | eHow - eHow | How to Videos ...

REGULATED INFORMATION FEBRUARY 4, 2014

TiGenix reaches major cell therapy milestone with 1000th implant of ChondroCelect

Leuven (BELGIUM) - February 4, 2014 - TiGenix (NYSE Euronext: TIG), a leader in the field of cell therapy, announced today that it reached a major milestone with the performance of the 1000th ChondroCelect implantation for cartilage repair in the knee. ChondroCelect is the first cell therapy that was granted approval by the European Medicines Agency (EMA) as an Advanced Therapy Medicinal Product (ATMP). Today it is routinely used in orthopedic centers of excellence across several European countries.

"A 1000 patients have already benefited from this innovative therapy, further supporting its efficacy and safety profile," said Eduardo Bravo, CEO of TiGenix. "A milestone such as today's is a clear demonstration of how far the cell therapy field has progressed over recent years, and I have no doubt that it is on its way to become a mainstay in clinical practice. We will continue to work towards turning our ChondroCelect franchise into a cash flow positive asset, and to push the clinical development of our pipeline of stem cell programs to a successful conclusion."

About ChondroCelect An innovative treatment, ChondroCelect has been shown to result in long-term durable clinical benefits in patients with recent cartilage lesions. Five-year follow-up data confirm that the therapeutic effect and the clinical benefit of ChondroCelect gained over baseline is maintained up to at least five years after the cartilage repair intervention. In addition, the data confirm that early treatment with ChondroCelect results in a superior clinical benefit over microfracture, and a lower failure rate.

Cartilage lesions of the knee are a frequent cause of disability in the active population. Caused by repetitive microtraumata, or due to sports or traffic accidents, cartilage lesions rarely heal spontaneously. When untreated, they predispose to osteoarthritis, which causes disability and represents a major socioeconomic burden. A treatment that allows symptom relief and functional recovery is key. To meet this important medical need, TiGenix developed ChondroCelect, the first cell therapy that was granted approval by the EMA as an ATMP.

ChondroCelect is administered to patients in an autologous chondrocyte implantation procedure known as Characterized Chondrocyte Implantation. TiGenix has designed a sophisticated manufacturing process to preserve the cells' characteristics and biological activity, and to maintain their ability to produce high quality cartilage. This process meets the highest quality standards and has been approved by the EMA.

For more information: Eduardo Bravo Chief Executive Officer eduardo.bravo@tigenix.com

Claudia D'Augusta Chief Financial Officer claudia.daugusta@tigenix.com

About TiGenix

See more here:
TiGenix : reaches major cell therapy milestone with 1000th.

A new method of producing stem cells is being described as a "game-changing" scientific breakthrough.

It is said that the research, carried out by scientists in Japan, could hail a new era of personalised medicine, offering hope to sufferers of diseases such as stroke, heart disease and spinal cord injuries.

The scientists bathed blood cells in a weak acidic solution for half an hour, which made the adult cells shrink and go back to their embryonic stem cell state. Using this process, a patient's own specially created stem cells could then be re-injected back into the body to help mend damaged organs.

The scientists in Japan used mice in this experiment but believe the approach may also work on human cells too.

The new method - much cheaper and faster than before - is being heralded as revolutionary, and could bring stem cell therapy a step closer, and all without the controversy linked to the use of human embryos.

But there is still research that some find ethically questionable.

On Inside Story: Is the controversy over using human embryos over? And how should ethics determine medical progress?

Presenter: Shiulie Ghosh

Guests:

Dusko Ilic, a reader in Stem Cell Science at King's College London School ofMedicine

Original post:
The ethics of medical progress

Purtier Placenta Stem Cell Therapy Presented By Dr. Chen
Presentasi Purtier Placenta oleh Dr. Chen Nikmati hidup bebas rasa sakit dan selalu awet muda bersama Purtier Placenta: http://www.stemcellworld.net.

By: Yohanes Wasono

The rest is here:
Purtier Placenta Stem Cell Therapy Presented By Dr. Chen - Video