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Category Archives: Stem Cell Therapy
Stem Cell Board Members Lubin and Sheehy Honored
Posted: December 2, 2012 at 7:58 am
A couple of members of the governing
board of the $3 billion California stem cell agency were honored for
their work this month.
Jeff Sheehy UCSF Photo |
One is Jeff Sheehy, a UCSF
communications manager and nationally known HIV/AIDS advocate, who
has served on the CIRM board since its inception. He was named by POZ
magazine as one of the top 100 “soldiers” in the fight against
HIV/AIDS.
communications manager and nationally known HIV/AIDS advocate, who
has served on the CIRM board since its inception. He was named by POZ
magazine as one of the top 100 “soldiers” in the fight against
HIV/AIDS.
CIRM's Amy Adams filed an item on
Sheehy on the agency's blog yesterday. She said,
Sheehy on the agency's blog yesterday. She said,
“Jeff once told me
that when he joined CIRM’s board eight years ago, he didn’t see a
role for stem cells in an HIV/AIDS treatment. Now, CIRM has committed
$40 million toward HIV/AIDS projects and two teams of researchers
from City
of Hope and UCLA are
working toward clinical trials.”
Sheehy was also invited to the White
House to commemorate World AIDs day Dec. 1.
House to commemorate World AIDs day Dec. 1.
Bert Lubin Childrens Hospital Photo |
Also honored was Bert Lubin, CEO of
Childrens Hospital in Oakland, where he has worked since 1973, a
remarkable achievement in today's world of transitory employment. The
San Francisco Business Times named Lubin as the “most admiredCEO” in the San Francisco Bay Area. The newspaper said that since
he took charge at Childrens in 2009,
Childrens Hospital in Oakland, where he has worked since 1973, a
remarkable achievement in today's world of transitory employment. The
San Francisco Business Times named Lubin as the “most admiredCEO” in the San Francisco Bay Area. The newspaper said that since
he took charge at Childrens in 2009,
“He recruited a new senior management
team, chopped away at the pediatric hospital’s operating deficit
and worked to heal relationships with the local community and
governmental and political leaders that were deeply frayed...”
On a personal note, a friend who has
long volunteered at Childrens gives him high marks as well, citing
several encounters where he exceeded the usual CEO effort.
long volunteered at Childrens gives him high marks as well, citing
several encounters where he exceeded the usual CEO effort.
Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/9b9s3mW2ebM/stem-cell-board-members-lubin-and.html
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Diane Winokur, Veteran ALS Patient Advocate, Named to California Stem Cell Agency Board
Posted: December 2, 2012 at 7:58 am
Longtime ALS patient advocate Diane
Winokur of San Francisco, who has lost two sons to the disease, has
been appointed to the governing board of the $3 billion California
stem cell agency.
She fills the vacancy left by David
Serrano Sewell, who resigned from the 29-member panel earlier this
year after serving since the agency's inception. CIRM has 10 patient advocates
on its board.
Serrano Sewell, who resigned from the 29-member panel earlier this
year after serving since the agency's inception. CIRM has 10 patient advocates
on its board.
Diane Winokur Photo -- Legal Momentum |
Winokur is well-known in ALS circles.
She sat for five years on the governing board of the national ALS
advocacy group and currently serves on the board for the California
state group, the Golden West chapter. She also served for six years on the board of
trustees for the Sanford- Burnham Institute in La Jolla, which has received $37 million from the stem cell agency. She left Sanford in 2011.
She sat for five years on the governing board of the national ALS
advocacy group and currently serves on the board for the California
state group, the Golden West chapter. She also served for six years on the board of
trustees for the Sanford- Burnham Institute in La Jolla, which has received $37 million from the stem cell agency. She left Sanford in 2011.
Last summer Winokur appeared before the
CIRM board to successfully seek approval of an $18 million ALS grant
that was rejected by the agency's reviewers. Researcher Clive
Svendsen of Cedars-Sinai in Los Angeles appealed the denial to the
full board and was supported in emotional testimony by other patient
advocates as well, including persons with the affliction.(See here for video of some of the testimony.)
CIRM board to successfully seek approval of an $18 million ALS grant
that was rejected by the agency's reviewers. Researcher Clive
Svendsen of Cedars-Sinai in Los Angeles appealed the denial to the
full board and was supported in emotional testimony by other patient
advocates as well, including persons with the affliction.(See here for video of some of the testimony.)
The agency has awarded about $30.6
million, including the Svendsen grant, for research directly related
to ALS.
million, including the Svendsen grant, for research directly related
to ALS.
Golden
West issued a press release Nov. 21, lauding the Winokur appointment
by California Lt. Gov. Gavin Newsom. The release quoted Lucie Bruijn,
chief scientist of The ALS Association, as saying,
West issued a press release Nov. 21, lauding the Winokur appointment
by California Lt. Gov. Gavin Newsom. The release quoted Lucie Bruijn,
chief scientist of The ALS Association, as saying,
"Her
contributions have been invaluable and she will be a tremendous asset
in moving the ALS research field forward through CIRM
funding."
The stem cell agency posted a blog item
on Winokur's appointment in addition to a press release. CIRM
Chairman J.T. Thomas said,
on Winokur's appointment in addition to a press release. CIRM
Chairman J.T. Thomas said,
“Her knowledge, expertise and
leadership will be a tremendous addition to the ICOC (the stem cell
agency governing board) and help guide us in our work.”
Patient advocate Don Reed of Fremont,
Ca., described Winokur in a 2008 blog item as “small, elegant, full
of energy, an exclamation point of a person.”
Ca., described Winokur in a 2008 blog item as “small, elegant, full
of energy, an exclamation point of a person.”
(Editor's note: Based on information from CIRM and Golden West, an earlier version of this item incorrectly stated that Winokur is a current member of the Sanford-Burnham board.
Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/dITcyP7WJbs/diane-winokur-veteran-als-patient.html
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Knoepfler Award Update: More than a Baker's Dozen Nominated
Posted: December 2, 2012 at 7:58 am
As of this week, 14 persons have been
recommended for the Knoepfler “Stem Cell Person of the Year”
Award.
The total was reported by Paul
Knoepfler, the UC Davis stem cell scientist and blogger, who is
putting up $1,000 for the winner of the honor.
Knoepfler, the UC Davis stem cell scientist and blogger, who is
putting up $1,000 for the winner of the honor.
Knoepfler announced his award plans earlier this month, declaring that he wanted to recognize scientists or others who “truly made a difference” in the stem
field. Risk-taking is one important criteria.
field. Risk-taking is one important criteria.
Knoepfler said,
“It’s something that I’m hoping I
can do every year. It would also be a reward for risk taking,
creativity and be breaking with tradition and be something new in
that regard.”
The award has drawn some modest
attention outside of Knoepfler's blog. A few days after he introduced
the award on his blog, UC Davis decided to put out a press release and video on it. The California Stem Cell Report followed with an item. Then CIRM blogged it as well.
attention outside of Knoepfler's blog. A few days after he introduced
the award on his blog, UC Davis decided to put out a press release and video on it. The California Stem Cell Report followed with an item. Then CIRM blogged it as well.
So far we have not detected any stories
about the award in the mainstream media, but things could change.
about the award in the mainstream media, but things could change.
Deadline for entries is Dec. 17.
Posted in Stem Cells, Stem Cell Therapy
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QualityStocks News – International Stem Cell Corp. Advances Groundbreaking Stem Cell Therapy with Distinct Advantages …
Posted: December 2, 2012 at 6:44 am
Company's ability to do something nobody has done before confirms world-leader status.
Scottsdale, AZ (PRWEB) November 30, 2012
In the companys news yesterday,
International Stem Cell Corp. has achieved a critical milestone towards the clinical development of its non-embryonic stem cell therapy.
Through much dedication and hard work, the companys research and development team has created the worlds first human clinical-grade stem cell lines that can be immune-match to millions of individuals. ISCOs existing research-grade parthenogenetic stem cell lines, one of which may be an immune-match to approximately 70 million people, are being used in pre-clinical development. ISCO is now in a position to conduct clinical trials in the United States.
Weve been working diligently for three years to perfect this technology, which was first developed by our scientific founder, Dr. Elena Revazova in Moscow, and Im excited to report that we have been able to derive new stem cell lines in the United States under the US and California regulatory frameworks. Im optimistic that the new parthenogenetic stem cell lines, by providing a potentially unlimited supply of cells and tissue for transplantation, will be of great benefit to the medical community and patients world-wide, stated Dr. Semechkin, CEO and Co-Chairman of the Board.
Created using ISCOs proprietary technology, the new stem cell lines represent the first of a new generation of clinical-grade human parthenogenetic stem cell (hpSC) lines created in the United States under US regulatory oversight and designed to meet FDA regulations. The US Food and Drug Administration developed Good Tissue Practice (GTP) and Good Manufacturing Practice (GMP) standards to ensure the safety of products developed for clinical use. Conforming to GMP is necessary to conduct clinical development programs.
Independent third-party testing has confirmed the new lines to be homozygous in the HLA coding regions. This means that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection; a distinct clinical advantage over embryonic stem cells. The company anticipates the new lines to immune-match millions of individuals. They will be added to ISCOs existing bank and provide a platform from which to develop cells and tissue for clinical use.
The importance of this breakthrough cannot be overstated, emphasized Dr. Craw, Executive Vice President of ISCO. Expanding our collection is not only important for our therapeutic programs, but also further establishes our leadership position in human stem cell technology. Achieving this critical milestone moves us along the path to make the transition into a clinical stage company.
About QualityStocks
Posted in Cell Therapy, Stem Cell Therapy
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Nobel Prize Nominee Plastic Surgeon Joins Patients Medical’s Stem Cell Research Team
Posted: November 30, 2012 at 7:40 am
Dr. Paul A. Dreschnack Offers New Options for Those With Hair Loss.
New York City, NY (PRWEB) November 29, 2012
Baldness can cause social anxiety, depression and many other emotional and psychological conditions. The solutions currently being offered such as transplants and pharmaceuticals can be uncomfortable or may compromise other aspects of the patients health, explains Dr. Dreschnack. In my work around the world, I strive to find ways for people to look good and feel well so that they are able to enjoy their lives fully. Stem Cell Therapy seems to be a new frontier that may be a way for patients to improve their quality of life.
Dr. Dreschnack is a four-time Nobel Prize Nominee for his work with The India Project. He has traveled internationally, helping patients who need plastic, cosmetic and reconstructive surgery. He is now working with Dr. Kamau Kokayi, Medical Director of the New York Stem Cell Treatment Center (NYSCTC) at Patients Medical.
We are excited that Dr. Dreschnack is joining our Stem Cell Research Team, says Dr. Kokayi.
Dr. Dreschnack has been the recipient of numerous awards including the Distinguished Surgeon Award from the Association of Operating Room Nurses, a 2002 Rose Model Award from the Young Leadership Council. He has been nominated for the The Raoul Wallenberg Medal, celebrating people who embody humanitarian ideals. He has also established himself as an academician, reviewing articles for the American Journal of Cosmetic Surgery, serving as Clinical Instructor at LSU School of Medicine/Department of Surgery and SUNY Health Science Center in Brooklyn. Dr. Dreschnack has also given presentations for the American Society for Surgery of the Hand and has been published in Medforum.com, Plastic and Reconstructive Surgery and the Proceedings of the American Association for Hand Surgery.
People interested in receiving plastic, cosmetic and reconstructive surgery at Patients Medical with Dr. Paul A. Dreschnack can inquire directly with Patients Medical for rates, a complete list of services and fees. Those interested in participating in the Stem Cell Therapy Clinical Trial may apply online at http://www.patientsmedical.com/stem-cell-therapy/registration-form.aspx
About Patients Medical
Patients Medical (http://www.patientsmedical.com) is a unique integrative medicine center in Manhattan that combines the best of traditional and holistic medicine with modern technology to provide comprehensive care. Established in 1974, the center employs a multi-specialty staff using leading-edge treatment protocols such as Stem Cell Therapy, Ultraviolet Blood Irradiation, Nutrient IV Therapy, Hyperbaric Oxygen Therapy and more. The practice specializes in diagnosing the root cause of an ailment, then healing the whole person with personalized protocols that draw upon both Eastern and Western medicine.
Megan Franzen Patients Medical 212-679-9667 111 Email Information
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Nobel Prize Nominee Plastic Surgeon Joins Patients Medical’s Stem Cell Research Team
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Stemlogix Reports Idaho Veterinarians Perform First in U.S. Combination Regenerative Medicine Treatment on Injured Horse
Posted: November 30, 2012 at 7:40 am
Procedure Combines Point-of-Care Stem Cell Therapy and Enriched Mesenchymal Stem Cell Injection
NAMPA, ID--(Marketwire - Nov 29, 2012) - Veterinarians from Idaho Equine Hospital, including Dr. William Maupin and Dr. Stuart Shoemaker, performed the first-ever combination regenerative medicine treatment on a six-year-old Quarter Reined Cow horse that suffered a significant injury to its distal straight sesamoidean ligament.
This injury can be challenging for veterinarians to successfully treat and return the horse to athletic competition.
The veterinary team and the scientific team at Stemlogix, LLC determined that the best treatment protocol would be to treat him with point-of-care stem cell therapy using the Stemlogix In-Clinic Regenerative Medicine System and then perform a follow up treatment a few weeks later using culture expanded mesenchymal stem cells. He received a dose of the point-of-care stem cell therapy three weeks ago and three weeks later received an injection of culture expanded mesenchymal stem cells.
Stemlogix, LLC pioneered the landmark stem cell therapy treatment regimen and this is the first time this combination stem cell therapy treatment has ever been performed on a horse. The team that treated the horse believes this revolutionary treatment protocol will give him the best chance for an improved quality of life and provides the best opportunity for restoring the injured tissue back to its normal structure instead of healing with scar tissue.
"Due to the severity of the injury and the poor circulation present in the sesamoidean ligament we elected to perform a two-step therapeutic approach," said Dr. Maupin. "We first injected adipose derived stem cell therapy produced patient-side to initiate an environment of healing.
"In addition, we injected culture expanded mesenchymal stem cells. This secondary expanded and enriched mesenchymal stem cell therapy treatment may further restore normal tissue structure or actual ligament tissue."
To provide him with this groundbreaking treatment, two small fat samples were taken from the base of his tail via a minimally invasive lipoaspirate procedure. Fat tissue is the richest source of stem cells for both human patients and animal patients. One of the tissue samples was processed on-site to provide a same-day, point-of-care stem cell treatment while the other tissue sample was sent to the Stemlogix state-of-the-art cGMP laboratory where the mesenchymal stem cells were isolated and expanded for three weeks. A portion of his stem cells were also cryopreserved for future use.
The Stemlogix In-Clinic Regenerative Medicine System rapidly produces a composition of stem cells at the point-of-care containing an abundance of mesenchymal stem cells, endothelial progenitor cells, among other cell types. This assortment of stem cells provides additional growth factors and therapeutic proteins to stimulate healing. This system offers veterinarians an optimal treatment tool that is convenient and effective in treating debilitating equine diseases and injuries.
On the other hand, the culture expanded stem cell therapy contains a high number of purified mesenchymal stem cells which makes this therapy better suited for treating specific indications such as orthopedic injuries, autoimmune diseases and other degenerative diseases. Mesenchymal stem cells are multi-potent or have the ability to form into a variety of new tissues such as bone, cartilage, ligaments, and tendons.
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Stemlogix Reports Idaho Veterinarians Perform First in U.S. Combination Regenerative Medicine Treatment on Injured Horse
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Stem Cell 101: Mayo Clinic Expert Answers Commonly Asked Questions
Posted: November 30, 2012 at 7:40 am
Released: 11/28/2012 3:45 PM EST Source: Mayo Clinic Expert Available
Newswise ROCHESTER, Minn. -- Next week, more than 1,200 people from 25 countries are expected to attend the 8th Annual World Stem Cell Summit in West Palm Beach, Fla., a gathering co-sponsored by Mayo Clinic. As those close to the science explore potential stem cell applications, many patients have questions about what stem cells are and how they are being used. Timothy Nelson, M.D., Ph.D., director of Mayo Clinics Regenerative Medicine Consult Service, answers some of the most commonly asked questions about stem cells:
MULTIMEDIA ALERT: Multimedia resources, including a Medical Edge package, are available for journalists to download on the Mayo Clinic News Network.
What are stem cells? Stem cells are the bodys raw materials. These cells have the ability to renew themselves or change to become specialized cells with a more specific function, such as blood cells, brain cells, heart muscle or bone.
Where do stem cells come from? Adult stem cells are found in tissues of the body, such as bone marrow. Emerging evidence suggests that adult stem cells may be more versatile than previously thought and have the ability to create other types of cells. Amniotic fluid stem cells come from the liquid that surrounds a developing fetus in the amniotic sac. More study of amniotic fluid stem cells is needed to understand their potential. Embryonic stem cells are a general stem cell found in embryos. Use of this type of stem cell has significantly declined due to the discovery of induced pluripotent stem cells. Induced pluripotent stem cells, commonly known as iPS cells, are derived from an adult stem cell that behaves like an embryonic stem cell. This new technique may help researchers avoid the controversy that comes with embryonic stem cells and prevent immune system rejection of the new stem cells. Mesenchymal stem cells are adult stem cells found in tissues such as bone marrow, blood and the fallopian tube. They can become bone, cartilage, fat and possibly other cells.
How are stem cells being used to treat diseases? Stem cell transplants, also known as bone marrow transplants, have been performed in the United States since the late 1960s. These transplants use adult stem cells.
Thanks to new technology, researchers are exploring the use of stem cells to treat a range of conditions. For example, teams at Mayo Clinic are investigating the use of adult stem cells to delay or eliminate the need for some hip replacements.
Adult stem cells are being tested to treat degenerative diseases such as heart failure. Stem cells from umbilical cord blood have been successfully used in clinical trials to treat cancer and blood-related diseases.
What does the future hold for stem cell therapy? The use of adult stem cells continues to be refined and improved. Researchers are discovering that these cells may be more versatile than originally thought, which means they may be able to treat a wider variety of diseases, such as diabetes; heart, liver and lung diseases; neurological and bone disorders; hand, face and other injuries; and congenital anomalies.
Dr. Nelson and other Mayo Clinic experts are available to discuss current research and the development of new stem cell therapies.
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Stem Cell 101: Mayo Clinic Expert Answers Commonly Asked Questions
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Professors Critique Stem Cell Medical Tourism
Posted: November 30, 2012 at 7:40 am
A panel at the Harvard Law School Wednesday discussed the ethical debate over the use of embryonic stem cells in the United States, focusing on the burgeoning controversy surrounding the role of stem cell therapy in medical tourism.
Medical tourism, in which patients travel internationally to gain access to specific health care services, has become increasingly common, panelists said. They said that reasons for medical tourism range from basic hip replacement surgery to black market organ sales. As most stem cell therapies are not approved in the United States, numerous patients are going abroad to countries like China and Russia where treatment is legal.
Panelist I. Glenn Cohen, an assistant professor at the Law School, said that it was probable that a Chinese stem cell facility performs several hundred thousand of these treatments yearly. He said that numerous celebrities, including football quarterback Peyton Manning, have reportedly traveled abroad to receive stem cell treatment not approved by the FDA.
A number of facilities claim to use stem cells to cure a wide array of diseases. University of Alberta law professor Timothy Caulfield, another panelist, pointed out that a simple Google search leads potential patients to a plethora of websites which claim that diseases such as autism and cancer can be cured through stem cell therapy.
Its being offered as routine, its being offered as safe, its being offered as effective, Caulfield said, citing his own 2008 study on the subject, Of course, none of them being offered matched what the scientific literature said.
According to American history professor Jill Lepore, the hyper-acceleration of enthusiasm for stem cell therapy is reminiscent of a century ago when science journalism and government funding for science research began to blossom. Lepore pointed out how public excitement over scientific procedures has affected society in the past, popularizing cryonics research and the work of Eugene Steinach, who claimed his vasectomy operation reversed the aging process.
Panelists said that one issue with stem cell tourism is the number of health risks associated with such procedures, citing a number of instances where stem cell therapy caused serious harm.
They also noted that public discussion about stem cell therapy has been markedly positive, lending an air of legitimacy to stem cell therapy that hasnt been validated by research.
Articles criticizing stem cell tourism, on the other hand, have generally received a less favorable response. Caulfield told the audience that when he co-wrote an article in The Atlantic criticizing stem cell therapy, he was accused as being a nutball Canadian socialist bioethicist.
The panelists emphasized that more accurate information should be provided to the public regarding stem cell treatments.
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Professors Critique Stem Cell Medical Tourism
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International Stem Cell Corporation Announces Significant Progress Towards Clinical Development
Posted: November 30, 2012 at 7:40 am
CARLSBAD, CA--(Marketwire - Nov 29, 2012) - International Stem Cell Corporation ( OTCQB : ISCO ) (www.internationalstemcell.com) ("ISCO" or "the Company"), a California-based biotechnology company focused on the development of therapeutic products, today announced the achievement of a critical milestone towards the clinical development of its stem cell therapy.
The Company's research and development team has created the world's first human clinical-grade stem cell lines with the ability to immune-match millions of individuals. ISCO's existing research-grade parthenogenetic stem cell lines, one of which contains the most common immune type in the Caucasian population and may be an immune-match to approximately 70 million people, are used in pre-clinical development. These new clinical-grade stem cell lines position ISCO to be able to conduct clinical trials in the United States.
Dr. Semechkin, CEO and Co-Chairman of the Board, comments, "We've been working diligently for three years to perfect this technology, which was first developed by our scientific founder, Dr. Elena Revazova in Moscow, and I'm excited to report that we have been able to derive new stem cell lines in the United States under the US and California regulatory frameworks. I'm optimistic that the new parthenogenetic stem cell lines, by providing a potentially unlimited supply of cells and tissue for transplantation, will be of great benefit to the medical community and patients world-wide."
The new stem cell lines, created using ISCO's proprietary technology, are the first of a new generation of clinical-grade human parthenogenetic stem cell (hpSC) lines created in the United States under US regulatory oversight and designed to meet FDA regulations. The US Food and Drug Administration developed Good Tissue Practice (GTP) and Good Manufacturing Practice (GMP) standards to ensure the safety of products developed for clinical use. Conforming to GMP is extremely important as it means that the cells can be used in clinical development programs.
The new lines have been confirmed by independent third-party testing to be "homozygous" in the HLA coding regions meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection. This feature is one of the most important differences of hpSC when compared with embryonic stem cells and a distinct clinical advantage because of their ability to be immune-matched to the patient. We expect the new lines to immune-match millions of individuals, and will be added to ISCO's existing bank providing a platform from which to develop cells and tissue for clinical use.
"The importance of this breakthrough cannot be overstated," commented Dr. Craw, Executive Vice President of ISCO. "Expanding our collection is not only important for our therapeutic programs, but also further establishes our leadership position in human stem cell technology. Achieving this critical milestone moves us along the path to make the transition into a clinical stage company."
About International Stem Cell Corporation
International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells (hpSCs) and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs) hence avoiding ethical issues associated with the use or destruction of viable human embryos. ISCO scientists have created the first parthenogenetic, homozygous stem cell line that can be a source of therapeutic cells for hundreds of millions of individuals of differing genders, ages and racial background with minimal immune rejection after transplantation. hpSCs offer the potential to create the first true stem cell bank, UniStemCell. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology (www.lifelinecelltech.com), and stem cell-based skin care products through its subsidiary Lifeline Skin Care (www.lifelineskincare.com). More information is available at http://www.internationalstemcell.com.
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International Stem Cell Corporation Announces Significant Progress Towards Clinical Development
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Stem Cell 101: Mayo Clinic Expert Answers Commonly Asked Questions
Posted: November 29, 2012 at 6:40 pm
Released: 11/28/2012 3:45 PM EST Source: Mayo Clinic Expert Available
Newswise ROCHESTER, Minn. -- Next week, more than 1,200 people from 25 countries are expected to attend the 8th Annual World Stem Cell Summit in West Palm Beach, Fla., a gathering co-sponsored by Mayo Clinic. As those close to the science explore potential stem cell applications, many patients have questions about what stem cells are and how they are being used. Timothy Nelson, M.D., Ph.D., director of Mayo Clinics Regenerative Medicine Consult Service, answers some of the most commonly asked questions about stem cells:
MULTIMEDIA ALERT: Multimedia resources, including a Medical Edge package, are available for journalists to download on the Mayo Clinic News Network.
What are stem cells? Stem cells are the bodys raw materials. These cells have the ability to renew themselves or change to become specialized cells with a more specific function, such as blood cells, brain cells, heart muscle or bone.
Where do stem cells come from? Adult stem cells are found in tissues of the body, such as bone marrow. Emerging evidence suggests that adult stem cells may be more versatile than previously thought and have the ability to create other types of cells. Amniotic fluid stem cells come from the liquid that surrounds a developing fetus in the amniotic sac. More study of amniotic fluid stem cells is needed to understand their potential. Embryonic stem cells are a general stem cell found in embryos. Use of this type of stem cell has significantly declined due to the discovery of induced pluripotent stem cells. Induced pluripotent stem cells, commonly known as iPS cells, are derived from an adult stem cell that behaves like an embryonic stem cell. This new technique may help researchers avoid the controversy that comes with embryonic stem cells and prevent immune system rejection of the new stem cells. Mesenchymal stem cells are adult stem cells found in tissues such as bone marrow, blood and the fallopian tube. They can become bone, cartilage, fat and possibly other cells.
How are stem cells being used to treat diseases? Stem cell transplants, also known as bone marrow transplants, have been performed in the United States since the late 1960s. These transplants use adult stem cells.
Thanks to new technology, researchers are exploring the use of stem cells to treat a range of conditions. For example, teams at Mayo Clinic are investigating the use of adult stem cells to delay or eliminate the need for some hip replacements.
Adult stem cells are being tested to treat degenerative diseases such as heart failure. Stem cells from umbilical cord blood have been successfully used in clinical trials to treat cancer and blood-related diseases.
What does the future hold for stem cell therapy? The use of adult stem cells continues to be refined and improved. Researchers are discovering that these cells may be more versatile than originally thought, which means they may be able to treat a wider variety of diseases, such as diabetes; heart, liver and lung diseases; neurological and bone disorders; hand, face and other injuries; and congenital anomalies.
Dr. Nelson and other Mayo Clinic experts are available to discuss current research and the development of new stem cell therapies.
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Stem Cell 101: Mayo Clinic Expert Answers Commonly Asked Questions
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