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Category Archives: Stem Cell Therapy
Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna Present at the Mid …
Posted: October 30, 2014 at 1:40 pm
Chicago, Illinois (PRWEB) October 30, 2014
On October 26th at the Mid American Regenerative and Cellular Medicine Showcase in Chicago, leading applied stem cell research scientist Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna presented talks on New Techniques for Enhancing Stem Cell Therapy Effectiveness and Orthopedic Surgical Applications For Stem Cells.
Dr. Riordan focused on historical medical uses of amniotic membrane and the properties of AlphaGEMS that include: wound healing; inflammation and pain reduction; fibrosis risk reduction; growth factor source; adhesion reduction; regeneration support and stem cell enhancement, specifically regarding the mesenchymal stem cells contained within BMAC.
Dr. McKenna discussed the latest applications of BMAC stem cells in orthopedic surgeries like anterior cruciate ligament (ACL) reconstruction and how BMAC injections can virtually eliminate infection risk, reduce complications, increase graft strength, reduce post-surgical inflammation and significantly reduce recovery time. Dr. McKenna also talked about how bone marrow can now be safely and relatively painlessly harvested using his patented BioMAC catheter under local, not general anesthesia.
Dr. Riordan and Dr. McKenna are co-founders of the Riordan-McKenna Institute (RMI), which will be opening soon in Southlake, Texas. RMI will specialize in regenerative orthopedics including non-surgical stem cell therapy and stem cell-enhanced surgery using bone marrow aspirate concentrate (BMAC) and AlphaGEMS amniotic tissue product.
Other noteworthy speakers in attendance included: Paolo Macchiarini, MD-PhD, Arnold Caplan, PhD and Mark Holterman, MD-PhD. Dr. Macchiarini and Dr. Holterman are well known for their work on the first stem cell trachea transplant. Dr. Caplan discovered the mesenchymal stem cell and is commonly referred to as the father of the mesenchymal stem cell.
About Neil Riordan PhD
Dr. Riordan is the co-founder of the Riordan-McKenna Institute (RMI), which will be opening soon in Southlake, Texas. RMI will specialize in regenerative orthopedics including non-surgical stem cell therapy and stem cell-enhanced surgery using bone marrow aspirate concentrate (BMAC) and AlphaGEMS amniotic tissue product.
Dr. Riordan is founder and chief scientific officer of Amniotic Therapies Inc. (ATI). ATI specializes in amniotic tissue research and development. Its current product line includes AlphaGEMS and AlphaPATCH amniotic tissue-based products.
Dr. Riordan is the founder and chairman of Medistem Panama, Inc., (MPI) a leading stem cell laboratory and research facility located in the Technology Park at the prestigious City of Knowledge in Panama City, Panama. Founded in 2007, MPI stands at the forefront of applied research on adult stem cells for several chronic diseases. MPI's stem cell laboratory is ISO 9001 certified and fully licensed by the Panamanian Ministry of Health. Dr. Riordan is the founder of Stem Cell Institute (SCI) in Panama City, Panama (est. 2007).
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The Miracle of Stem Cell Therapy at Adler Footcare Regenerates Cells, Heals Foot Pain
Posted: October 29, 2014 at 7:40 pm
New York, New York (PRWEB) October 29, 2014
Stem cell therapy is the future of foot pain treatment. New York podiatrists at Adler Footcare are using ethical stem cell treatments for foot problems to help speed healing, minimize pain, and reduce swelling.
Stem cells are cells that havent quite yet determined their role in the body. This gives them the ability to turn into anything. The treatment is being used for problems causing foot pain, such as Achilles tendonitis, plantar fasciitis, and arthritis of the first toe joint. Stem cells help regenerate new cartilage and helps tissue heal much quicker.
"Stem cells turn into everything," said Dr. Jeffrey Adler, Medical/Surgical Director & Owner of Adler Footcare. "So basically, if the damage is due to cartilage, they turn into cartilage. If the damage is due to soft tissue, they turn into soft tissue. Its the Swiss army knife of treatments."
The stem cells are not live embryos, but instead are generated from the placenta and ethically obtained during the C-sections of live births. The women who the cells are taken from are screened and tested for any communicable diseases beforehand.
Stem cell therapy uses a minimally invasive technique to inject the cells directly into the area where the patient is feeling the foot pain. Fluoroscopy is used to determine the exact position for injection. When stem cell therapy is used healing occurs twice as fast. As the tissues are regenerated and the swelling is minimized, the patient is able to experience more range of motion, less post-operative pain, and less inflammation.
The New York podiatrists at Adler Footcare have been using stem cell therapy for 2 years. They continue to stay up-to-date on the process and have seen only positive results.
To learn more about stem cell treatment for foot pain, contact a New York podiatrist at Adler Footcare.
About Dr. Jeffrey L. Adler
Dr. Jeffrey L. Adler, Medical/Surgical Director and Owner of Adler Footcare of Greater New York has been practicing podiatric medicine since 1979 and has performed thousands of foot and ankle surgeries. Dr. Adler is board certified in Podiatric Surgery and Primary Podiatric Medicine by the American Board of Multiple Specialties in Podiatry. Dr. Adler is also a Professor of Minimally Invasive Foot Surgery for the Academy of Ambulatory Foot and Ankle Surgeons. As one of only several in the country who perform minimally invasive podiatric surgery, Dr. Adlers patients enjoy significantly reduced recovery times.
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The Miracle of Stem Cell Therapy at Adler Footcare Regenerates Cells, Heals Foot Pain
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Gene therapy, stem cell therapy trials underway
Posted: October 29, 2014 at 7:40 pm
Stem cells and gene hold promising treatment options for Parkinson's, mandate doctors across the globe, including from Mumbai. Eleven trials to test stem cell and gene therapy for treating Parkinson's are underway currently of which the one in Mumbai had to be put on hold due to regulatory hurdles.
Currently, neuro-augmentative therapies such as usage of drugs or deep brain stimulation (DBS) are being used to treat Parkinson's disorder. "The future holds hope for neuro-restorative therapies like that of stem cells or gene infusion in the Parkinson's disorder treatment. It involves restoration of brain function to normal. In the next five to seven years, this may pave the way for future," said Dr Paresh Doshi, neurologist at Jaslok Hospital, Peddar Road in Mumbai.
Regulatory hurdles and resource constraints though have led to these trials being held up in Mumbai. Dr Doshi said that trials of Duodopa therapy which involves infusion of an active ingredient gel called Levodopa in the intestines has been kept on hold at the moment at privately-run Jaslok Hospital due to regulatory hurdles. The hospital was the only centre in entire South East Asia to have been running the trial.
"Levodopa gets converted into dopamine in the body. Normal levels of dopamine control Parkinsons disorder," said Dr Doshi.
Trials to infuse stem cells from the patient's body in the patient itself had been underway in small group of patients in India, but due to inability to recruit more patients, the trial was stopped. "We could only recruit four patients for two years. However, a similar trial is underway in China and another trial which explores adipose tissue stem cells in treating Parkinson's disease is underway in South Africa," said Dr Doshi.
In January this year, medical journal The Lancet reported that after sixteen years of trials, gene therapy is showing promising results in humans. "Three genes that promote the formation of dopamine generating cells in the brain were injected in the brain bound with a viral vector in fifteen patients. The genes are intended to boost the production of dopamine, a chemical that becomes deficient in patients withParkinson's," said The Lancet report.
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Gene therapy, stem cell therapy trials underway
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My Pet World: Stem cell treatments show promise for some feline health issues
Posted: October 29, 2014 at 2:43 am
Q: You recently wrote about stem cell research, and I understand that stem cell therapy is being used to treat inflammatory bowel disease in cats. Do you have more details?
A: The Winn Feline Foundation has funded the research of Dr. Craig Webb and Dr. Tracy Webb of Colorado State University College of Veterinary Medicine to study the use of stem cells to treat inflammatory bowel disease in cats. Early results are promising.
Stem cell research in cats doesn't stop there. Dr. Glenn Olah, president of the Winn Feline Foundation, notes that Winn also funded stem cell studies to treat feline asthma and kidney disease. Results are hopeful, but it's simply too early to offer definitive answers.
"In some ways, stem cell studies in pets are ahead of (those in) people."
Q: About a month ago, I adopted a beautiful Burmese after she romanced me at the shelter. Once we got home, she wanted nothing to do with me. It's not that she isn't friendly. She loves my son and even sleeps with him. When I get up early to feed her, she stays away until I've left the room. My son suggested that the cat harbors resentment toward me because I took her from her cat friends. What can do to improve the situation?
A: "The good news is that it's very unlikely the cat harbors any resentment," said Winn Feline board member and feline veterinarian Dr. Drew Weigner, of Atlanta. "The bad news for you -- but good news for the cat and your son -- is that they developed a fast friendship.
Here are tips that might help the cat warm up to you:
Sit on the floor in an empty room with her. Close the door, but provide an empty box or two for the cat to hop into. Then, simply watch TV, or read a children's story out loud. Cats sometimes like that soft sing-song voice we tend to use when reading children's stories.
Wait until the cat comes to you. It may take several days, but eventually curiosity will out.
Next, take over feeding the cat, even if she waits for you to leave the room to eat.
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My Pet World: Stem cell treatments show promise for some feline health issues
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Stem Cell Therapies – Healing and Stem Cell Therapy …
Posted: October 27, 2014 at 7:43 pm
Health is life, and life is the promise of hopehope for today, hope for tomorrow, and hope for a better future. When illness strikes doubt is cast across that life. You can think of nothing else. You wonder, Why me? Why now? What can I do? Where can I turn for help? You ask questions to which there seem to be no answer. What you want more than anything is to have your health backto have your life back. How can you have life if you have a degenerative illness?
Exciting innovations in medical science can answer that question today in a way that weve never been able to answer it before: stem cell therapies.
Health deteriorates over time resulting in illness. Degenerative illnesses require regenerative cures. In stem cell therapies we find the regenerative treatments were looking for, opening new doors to health and happiness once thought closed due to a serious illness. Most of us have no idea that these stem cell therapies have been performed every day in foreign countries for years. They are not some far-off and distant dream; theyre happening now.
If you are experiencing the effects of living with a serious illness, I want you to know that you are not alone. I hope to be the helping hand youre looking for. I have seen people regain the lives they lost to a degenerative illness when they found a cure, and if youre suffering with serious illness, I can bring you the therapies that will achieve the same results for you: a new life. J. Cohan & Associates works with hospitals and doctors that perform stem cell therapies for your specific condition. All of the facilities are modern, state-of-the-art clinics and hospitals staffed by highly trained doctors who are experienced in the field of stem cell therapy. Again, these therapies are not simply theoretical cures for an imaginary future; they have been proven and used successfully for years.
For anyone who has spent years of their life or the majority of their savings on treatments while seeing few, if any, results, or those who are watching their friends and loved ones die because all of the known treatment options have been exhausted, know that there is hope. Anyone who is still willing to explore these amazing treatments can find the promise of a better tomorrow. Life is hope, but, for there to be life, there must be health, and creating the healthiest life possible for you or someone you love requires that you keep moving forward as long as there is still breath to draw from. Stem cell therapies have brought healing where all hope of healing had been lost. Let us begin today to build a better future, together.
For more information on how stem cell therapies can help you in recovering from a serious degenerative condition, please contact Jim Cohan & Associates at 818-504-2318.
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Cancer-Killing Stem Cells Engineered In Lab
Posted: October 27, 2014 at 7:43 pm
Scientists from Harvard Medical School have discovered a way of turning stem cells into killing machines to fight brain cancer.
In experiments on mice, the stem cells were genetically engineered to produce and secrete toxins which kill brain tumours, without killing normal cells or themselves.
Researchers said the next stage was to test the procedure in humans.
A stem cell expert said this was "the future" of cancer treatment.
The study, published in the journal Stem Cells, was the work of scientists from Massachusetts General Hospital and the Harvard Stem Cell Institute.
For many years, they had been researching a stem-cell-based therapy for cancer, which would kill only tumour cells and no others.
They used genetic engineering to make stem cells that spewed out cancer-killing toxins, but, crucially, were also able to resist the effects of the poison they were producing.
They also posed no risk to normal, healthy cells.
In animal tests, the stem cells were surrounded in gel and placed at the site of the brain tumour after it had been removed.
Their cancer cells then died as they had no defence against the toxins.
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Stem Cell Therapy Help Buddy the Beagle – Video
Posted: October 25, 2014 at 4:49 am
Stem Cell Therapy Help Buddy the Beagle
Buddy the beagle wasn #39;t able to walk when he first arrived at the University of Minnesota Veterinary Medical Center. With the help of the Veterinary Medical ...
By: UMN Health
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Tuffy stem cell therapy patient – Video
Posted: October 24, 2014 at 10:46 pm
Tuffy stem cell therapy patient
Tuffy 2 months after he received Stem Cell Therapy here. He is running around now like nothing happened. I can not believe he was hit by a car and broke his back in 2 places just 2 months ago.
By: Noel Berger
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Tuffy stem cell therapy patient - Video
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UCLA and UCI Awarded $8M Grant to Launch Collaborative Stem Cell Clinic "Center of Excellence"
Posted: October 24, 2014 at 8:40 am
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Newswise In a first-of-its-kind collaboration, the University of California, Los Angeles, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and University of California, Irvine Sue & Bill Gross Stem Cell Research Center received a five year $8M grant from the California Institute of Regenerative Medicine (CIRM), the states stem cell agency, to establish a CIRM Alpha Stem Cell Clinic center of excellence to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research.
The $8M grant was one of three awarded today by CIRM as part of the CIRM Alpha Stem Cell Clinics (CASC) Network Initiative. The joint UCLA/UCI award under the direction of Dr. John Adams, a member of the UCLA Broad Stem Cell Research Center and professor in the department of orthopaedic surgery, will accelerate the implementation of clinical trials and delivery of stem cell therapies by providing world-class, state-of-the-art infrastructure to support clinical research.
CIRM grant reviewers lauded the UCLA/UCI Consortiums impressive and multidimensional team of experienced personnel that will expand access to patients, attracting national and international clinical trials and accelerating future trials in the pipeline.
The initial stem cell trials supported by the UCLA/UCI Alpha Stem Cell Clinic will be two UCLA projects using blood forming stem cells. The first trial will test a stem cell-based gene therapy for patients with bubble baby disease, also called severe combined immune deficiency (SCID), in which babies are born without an immune system. Under the direction of Dr. Donald Kohn, the clinical trial will use the babys own stem cells with an inserted gene modification to correct the defect and promote the creation of an immune system. The second clinical trial, under the direction of Dr. Antoni Ribas, will use patients own genetically modified blood-forming stem cells to engineer and promote an immune response to melanoma and sarcomas.
This CIRM Alpha Stem Cell Clinic grant is an important acknowledgement of our cutting-edge research and will help us to advance the design, testing and delivery of effective and safe stem cell-based therapies, said Dr. Owen Witte, professor and director of the Broad Stem Cell Research Center. The implementation of a standard of excellence in clinical research will improve healthcare and the lives of patients far beyond the longevity of individual trials.
Operating as part of the larger state-wide CIRM supported network, Alpha Stem Cell Clinics provide critical operational support to conduct clinical trials, with focused resources and expertise in stem cell-based clinical research including clinical operations support and patient care coordination personnel.
UCI has established a strong preclinical stem cell research program, and its vital to move ahead to the clinical testing phase, said Sidney Golub, director of UCIs Sue & Bill Gross Stem Cell Research Center. To advance treatments in this field, we all have to work together, and thats what the UCLA-UCI Alpha Stem Cell Clinic program represents.
About the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
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UCLA and UCI Awarded $8M Grant to Launch Collaborative Stem Cell Clinic "Center of Excellence"
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NYSCF Research Institute announces largest-ever stem cell repository
Posted: October 23, 2014 at 7:40 am
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The New York Stem Cell Foundation (NYSCF) Research Institute, through the launch of its repository in 2015, will provide for the first time the largest-ever number of stem cell lines available to the scientific research community. Initially, over 600 induced pluripotent stem (iPS) cell lines and 1,000 cultured fibroblasts from over 1,000 unique human subjects will be made available, with an increasing number available in the first year. To collect these samples, NYSCF set up a rigorous human subjects system that protects patients and allows for the safe and anonymous collection of samples from people interested in participating in research.
A pilot of over 200 of NYSCF's iPS cell lines is already searchable on an online database. The pilot includes panels of iPS cell lines generated from donors affected by specific diseases such as type 1 diabetes, Parkinson's disease, and multiple sclerosis, as well as a diversity panel of presumed healthy donors from a wide range of genetic backgrounds representing the United States Census. These panels, curated to provide ideal initial cohorts for studying each area, include subjects ranging in age of disease onset, and are gender matched. Other panels that will be available in 2015 include Alzheimer's disease, schizophrenia, Juvenile Batten disease, and Charcot-Marie-Tooth disease.
"NYSCF's mission is to develop new treatments for patients. Building the necessary infrastructure and making resources available to scientists around the world to further everyone's research are critical steps in accomplishing this goal," said Susan L. Solomon, CEO of The New York Stem Cell Foundation.
NYSCF has developed the technology needed to create a large collection of stem cell lines representing the world's population. This platform, known as the NYSCF Global Stem Cell ArrayTM, is an automated robotic system for stem cell production and is capable of generating 200 iPS cell lines a month from patients with various diseases and conditions and from all genetic backgrounds. The NYSCF Global Stem Cell ArrayTM is also used for stem cell differentiation and drug screening.
Currently available in the online database that was developed in collaboration with eagle-i Network, of the Harvard Catalyst, is a pilot set of approximately 200 iPS cell lines and related information about the patients. This open source, open access resource discovery platform makes the cell lines and related information available to the public on a user-friendly, web-based, searchable system. This is one example of NYSCF's efforts to reduce duplicative research and enable even broader collaborative research efforts via data sharing and analysis. NYSCF continues to play a key role in connecting the dots between patients, scientists, funders, and outside researchers that all need access to biological samples.
"The NYSCF repository will be a critical complement to other existing efforts which are limited in their ability to distribute on a global scale. I believe that this NYSCF effort wholly supported by philanthropy will help accelerate the use of iPS cell based technology," said Dr. Mahendra Rao, NYSCF Vice President of Regenerative Medicine.
To develop these resources, NYSCF has partnered with over 50 disease foundations, academic institutions, pharmaceutical companies, and government entities, including the Parkinson's Progression Markers Initiative (PPMI), PersonalGenomes.org, the Beyond Batten Disease Foundation, among several others. NYSCF also participates in and drives a number of large-scale multi stakeholder initiatives including government and international efforts. One such example is the Cure Alzheimer's Fund Stem Cell Consortium, a group consisting of six institutions, including NYSCF, directly investigating, for the first time, brain cells in petri dishes from individual patients who have the common sporadic form of Alzheimer's disease.
"We are entering this next important phase of using stem cells to understand disease and discover new drugs. Having collaborated with NYSCF extensively over the last five years on the automation of stem cell production and differentiation, it's really an exciting moment to see these new technologies that NYSCF has developed now being made available to the entire academic and commercial research communities," said Dr. Kevin Eggan, Professor of Stem Cell and Regenerative Biology at Harvard University and Principal Investigator of the Harvard Stem Cell Institute.
NYSCF's unique technological resources have resulted in partnerships with companies to develop both stem cell lines and also collaborative research programs. Over the past year, NYSCF has established collaborations with four pharmaceutical companies to accelerate the translation of basic scientific discoveries into the clinic. Federal and state governments are also working with NYSCF to further stem cell research in the pursuit of cures. In 2013, NYSCF partnered with the National Institutes of Health (NIH) Undiagnosed Disease Program (UDP) to generate stem cell lines from 100 patients in the UDP and also collaborate with UDP researchers to better understand and potentially treat select rare diseases.
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NYSCF Research Institute announces largest-ever stem cell repository
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