Category Archives: Stem Cells

What are, and how we use Stem Cells
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What are, and how we use Stem Cells - Video

Tuesday, May 14th, 2013 Issue 20, Volume 17.

RIVERSIDE - A UC Riverside professor will give a free lecture about stem cells at UCR's Extension Center later this month, a campus spokesman said today.

The May 30 lecture, "Promise of Stem Cells: Hope or Hype?" will be given by Nicole zur Nieden, an assistant professor of cell biology and neuroscience at UCR.

Zur Nieden will discuss whether stem cells -- which can become specialized cells with specific functions and can be used to regenerate and repair diseased or damaged tissues -- are a "miracle cure," Advertisement [ Pala Mesa Resort ] according to UCR spokesman Iqbal Pittalwala.

Zur Nieden, a biologist and expert in stem cell biology, toxicology and bioengineering, is a member of UCR's Stem Cell Center. Her research group is working to understand how embryonic stem cells develop into bone tissue, Pittalwala said.

The 5:30 p.m. lecture is the fourth and last talk in the annual Science Lecture Series hosted by the College of Natural and Agricultural Sciences. This year's theme is "The Science of Disease."

Seating for the lecture is open, and parking is free.

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Free lecture on regeneration of damaged tissues with stem cells offered at UC Riverside

GOLDEN, Colo. (CBS4) In an effort to live a long and healthy life, some adults are now taking out a different kind of insurance policy. They are banking their stem cells for future use.

CBS4 Health Specialist Kathy Walsh watched one man go through the process. Its relatively simple but it can set a person back several thousand dollars. Still, one retired engineer believes it is worth the investment.

I am just a 54-year-old whos trying to figure out how to get the most out of life, Matt Rockwell said. Were told that we can live, at least machinery wise, we can live to 120. Id like my 120.

In fact, Rockwell is banking on that. In his doctors office in Golden, he is saving cells. Five vials of blood were collected. Then, Dr. Terry Grossman took a small sample of Rockwells skin cells.

Grossman practices nutritional and anti-aging medicine and has written three books about longevity.

Right now, stem cell therapies are in their infancy, Grossman said.

But Grossman believes the possibilities are endless.

Whats going to be available in 10 to 20 years, it boggles the imagination, he said.

So Grossman collects stem cells for patients and sends them away to be grown and cryopreserved. The belief is they may later be used to treat various diseases or conditions.

Animals are having wonderful results and we are able to create, for instance, rat hearts and mouse hearts; and we are able to grow new cartilage for race horses, Grossman said.

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Some People Banking Stem Cells For Future Use To Stay Healthy

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/3724fc/mesenchymal_stem) has announced the addition of the "Mesenchymal Stem Cells - Advances & Applications 2013" report to their offering.

Understand and profit from the mesenchymal stem cell (MSC) product market - the fastest growing area of stem cell research.

Updated to reflect the most current trends and including five year market projections, this report focuses on the advances in MSC research. In 125 pages you'll explore research priorities by market segment, highlight individual labs and end-users of MSC products, understand the competitive environment for such products and discover market-leading trend analysis.

Revealing Unique Strategic Opportunities & Unknown Competitive Advantages

MSCs are advantageous over other stem cells types for several reasons. First, they avoid the ethical issues that surround embryonic stem cell research. Second, repeated studies have found that human MSCs are immuno-privileged, and therefore, represent an advantageous cell type for allogenic transplantation, reducing the risks of rejection and complications of transplantation. Recently, there have also been significant advances in the use of autologous MSCs to regenerate human tissues, including cartilage and meniscus, tendons, and bone fractures.

This market research report focuses on recent advances in MSC research applications, explores research priorities by market segment, highlights individual labs and end-users of MSC research products, explores the competitive environment for MSC research products, and provides 5-year growth and trend analysis. The report advantageously positions companies that wish to offer competitive stem cells products to this rapidly growing, well-funded research community.

Expanded and Updated Market Intelligence

This is an expanded and updated market intelligence report that includes:

- Updated Charts, Timelines, Metrics and Financials

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Research and Markets: Mesenchymal Stem Cells - Advances & Applications 2013

In free public lecture on May 30 at UC Riverside stem-cell expert Nicole zur Nieden will discuss the enthusiasm and caveats surrounding stem cell therapy

By Iqbal Pittalwala on May 14, 2013

Nicole zur Nieden is an assistant professor of cell biology and neuroscience at UC Riverside. Photo credit: Zur Nieden Lab, UC Riverside.

RIVERSIDE, Calif. Stem cells are mother cells that can become specialized cells with a more specific function, such as brain cells, blood cells, heart muscle or bone. Because they can be used to regenerate and repair diseased or damaged tissues in people, they have, at times, been portrayed as a miracle cure for a variety of conditions and disabilities.

But are they the miracle cure? Or is that an exaggeration? How do we separate fact from fiction and hope from hype when it comes to stem cell therapy?

Nicole zur Nieden, an assistant professor of cell biology and neuroscience at the University of California, Riverside, will give a free public lecture at UC Riverside on May 30 in which she will discuss whether the claims for stem cells can be justified.

Her hour-long talk is titled The promise of stem cells: Hope or hype? It will begin at 5:30 p.m. in Rooms C, D and E, University Extension Center (UNEX). Seating is open. Parking at UNEX is free for lecture attendees.

The lecture is the fourth and final talk in the annual Science Lecture Series hosted by the College of Natural and Agricultural Sciences (CNAS). This year the theme is The Science of Disease. The series aims to boost the publics awareness and understanding of science and of how scientists work.

Zur Nieden, a biologist by training with expertise in stem cell biology, toxicology and bioengineering, joined UCR in 2008. She is a member of UCRs Stem Cell Center. Her research group has established that functioning skeletal cell types are generated from embryonic stem cells, and has developed a comprehensive analysis of the expression of bone marker genes and enzymatic activity specific to bones.

Currently, her group is working to understand how embryonic stem cells develop into bone tissue. Her lab also is attempting to understand molecular regulators of normal bone development, and to deduce new therapeutic targets, which could be pinpointed during disease intervention in the clinic.

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Stem Cells: Hope or Hype?

May 14, 2013 In new research published online May 13, 2013 in Advanced Materials, researchers from Brigham and Women's Hospital (BWH) are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce stem cells to become bone cells without the need of additional bone-inducing factors. Synthetic silicates are made up of simple or complex salts of silicic acids, and have been used extensively for various commercial and industrial applications, such as food additives, glass and ceramic filler materials, and anti-caking agents.

"With an aging population in the US, injuries and degenerative conditions are subsequently on the rise," said Ali Khademhosseini, PhD, BWH Division of Biomedical Engineering, senior study author. "As a result, there is an increased demand for therapies that can repair damaged tissues. In particular, there is a great need for new materials that can direct stem cell differentiation and facilitate functional tissue formation. Silicate nanoplatelets have the potential to address this need in medicine and biotechnology."

"Based on the strong preliminary studies, we believe that these highly bioactive nanoplatelets may be utilized to develop devices such as injectable tissue repair matrixes, bioactive fillers, or therapeutic agents for stimulating specific cellular responses in bone-related tissue engineering," said Akhilesh Gaharwar, PhD, BWH Division of Biomedical Engineering, first study author. "Future mechanistic studies will be performed to better understand underlying pathways that govern favorable responses, leading to a better understanding of how materials strategies can be leveraged to further improve construct performance and ultimately shorten patient recovery time."

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The above story is reprinted from materials provided by Brigham and Women's Hospital, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Using clay to grow bone: Researchers use synthetic silicate to stimulate stem cells into bone cells

Dallas, Texas (PRWEB) May 12, 2013

Analysis of global grant activity, scientific publication rates, and patent applications reveal that research activity involving mesenchymal stem cells increased 58% year-over-year from 2008 to 2009, and 112% from 2009 to 2010. Of most interest is that this rate of growth accelerated in 2011, making mesenchymal stem cells the fastest growing area of stem cell research.

Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, beta-pancreatic islets cells, and potentially, neuronal cells. MSCs are of intense therapeutic interest because they represent a population of cells with the potential to treat a wide range of acute and degenerative diseases.

Revealing Unique Strategic Opportunities & Unknown Competitive Advantages MSCs are advantageous over other stem cells types for several reasons. First, they avoid the ethical issues that surround embryonic stem cell research. Second, repeated studies have found that human MSCs are immuno-privileged, and therefore, represent an advantageous cell type for allogenic transplantation, reducing the risks of rejection and complications of transplantation. Recently, there have also been significant advances in the use of autologous MSCs to regenerate human tissues, including cartilage and meniscus, tendons, and bone fractures.

This market research report focuses on recent advances in Mesenchymal stem cells research applications, explores research priorities by market segment, highlights individual labs and end-users of MSC research products, explores the competitive environment for MSC research products, and provides 5-year growth and trend analysis. The report advantageously positions companies that wish to offer competitive stem cells products to this rapidly growing, well-funded research community.

Expanded and Updated Market Intelligence This is an expanded and updated market intelligence report that includes:

Highlights of this report http://www.reportsnreports.com/reports/10598-mesenchymal-stem-cells-advances-applications.html include:

These sources were used to identify recent advances in MSC research applications, explore research priorities by market segment, highlight individual labs and end-users of MSC research products, explore the competitive environment for MSC research products, and provide 5-year growth and trend analysis. As such, this market intelligence report will advantageously position ones company to offer competitive MSC products to this rapidly growing, well-funded research community.

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In summary, literature and data concerning the biology and differentiation potential of mesenchymal stem cells (MSCs) has become huge in less than 10 years, now totaling nearly 13,000 publications, although some data does present as contradictory, suggesting a heterogenic nature for MSC populations depending on source tissue, species, and donor characteristics. MSCs appear to be an exceptionally promising tool for cell therapy because of their unusual characteristics, which partially mimic those of embryonic stem cells, but have advantages in terms of availability, expandability, transplantability, and ethical implications.

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Mesenchymal Stem Cells Market- MSC Product is Stem Cells Fastest Growing Area Says New Research Report at ...

May 13, 2013 12:15pm

(Image Credit:Francois Lenoir/Reuters)

A Dutch scientist hopes hell change minds about the viability of test tube meat when his first genetically engineered hamburger, made from billions of stem cells, is served hot off the grill.

Mark Post, the head of physiology at Maastricht University in the Netherlands, has spent years growing the synthetic hamburger from bovine stem cells, which his teamturned into thin strips of muscle tissue before mincing them into a patty.

RELATED: Lab-Grown Meat: Food of the Future?

While the process has taken time and run upconsiderable expense the project received $325,000 from an anonymous donor Post told the New York Times he hoped the cost of cultured meat could come down in the future, making it a viable food source.

After conducting an informal tasting, Post gave the synthetic tissue his seal of approval, telling the Times, it tastes reasonably good and that he planned to add just salt and pepper before serving it, perhaps at an event in London this summer.

Post told ABC News in 2011 that he expected meat consumption to double in the next 40 years.

In my mind, meat consumption is here to stay, and if you want to do that at a higher efficiency than what is currently done by cows and pigs, you have to explore the possibility of doing that in the lab, he said.

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Hot off the Grill: Burgers Made From Billions of Stem Cells

A new study that's based in Baltimore is exploring the use of stem cells and fat grafting for cosmetic and reconstructive procedures.

As people age, the fat in their face decreases, and that can often make people look older.

A woman in her 60s who 11 News did not identify said she wanted to freshen her look but didn't want to go through a face-lift operation like she did several years before. Instead, Mercy Medical Center's Dr. Craig Vander Kolk used her own fat stem cells.

"By using fat, we can reshape all of that and build it up," Vander Kolk said, pointing to areas upon which the woman wanted to improve.

He is currently conducting a fat-grafting study at Mercy in which he takes the fat stem cells from a patient's abdomen. They are then used cosmetically and for breast reconstruction, among other things.

"If we use them in areas where there's been an injury, they help heal the injury. If we take fat and stem cells, we can make the skin more healthy, improve scars and improve diseases that can cause the skin to thin," Vander Kolk said.

He said fat is better for cosmetic procedures because, while fillers need to be repeated every six months or year, the stem cells and fat stay, leaving a longer-lasting result.

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Study uses stem cells, fat to repair skin