What is CAR T-cell Therapy? | BMT Infonet – BMT Infonet |

Posted: August 22, 2022 at 3:01 am

Chimeric Antigen Receptor T-cell (CAR T-cell) therapy is a new approach to fighting cancer using the patients own immune system.

Certain immune system cells, called T-cells or T-lymphocytes, are normally able to identify abnormal cells, like cancer cells, and destroy them before they multiply and cause disease. Sometimes, however, T-cells have trouble detecting cancer cells.

CAR T-cell therapy removes T-cells from the blood and inserts a new gene into them to make it easier for the T-cells to fight cancer. The new cells are called CAR T-cells.These CAR T-cells arethen infused into the patient to fight cancer.

As of August, 2022 the FDA has approved the following CART-cell therapies for patients who relapsed, or did not respond totreatment, after several rounds of chemotherapy:

The specific CAR T-therapy available to you will vary dependingon the medical center where you are receiving treatment. Your insurance plan may limit coverage to specific CAR T-therapies.

Your treatment center mayoffer you an opportunity to participate in a clinical trial testing anew type of CAR T-cell therapy.Research is underway to determine if patients with other typesof cancer such as chronic lymphocytic leukemia (CLL), acutemyeloid leukemia (AML), Hodgkin lymphoma andsome solidtumors can also benefit from CAR T-cell therapy.

NEXT: Steps Involved in CAR T-cell Therapy

Updated August, 2022

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What is CAR T-cell Therapy? | BMT Infonet - BMT Infonet |

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