Diabetes both type 1, which is an incurable autoimmune disorder, and type 2 which is a lifestyle disease that can be reversed or cured are among the fastest-growing diagnoses in the world. Left untreated, they can cause life-threatening conditions and death. So its not surprising that the medical establishment is pumping resources into new methods of management.
What makes them worthy of talking about here on Geek is that technology is playing a major role. Todays diabetic is often wired up with Bluetooth sensors and custom software that turn them into virtual cyborgs with an awareness of their body chemistry that normal people cant match.
Heres a quick rundown of diabetes if youre not familiar with the condition. When you eat food, its split into three basic categories: carbohydrates, fats, and proteins. Carbohydrates, which are found primarily in plant products, break down into a sugar called glucose in your digestive system. That glucose is turned into fuel to power your mind and muscles.
The body does that conversion with a hormone called insulin, which is produced by beta cells in the pancreas. Type 1 diabetics dont make it at all their immune system destroys those beta cells for an as yet unknown reason. Type 2 diabetics make it, but for some reason its less efficient at breaking down glucose into energy.
When the body cant break down glucose, it has to get energy from other places mostly fat, but nothing is safe. That leads to a state of ketosis, where acids released from fats build up. Those acids can cause a wide variety of nerve and tissue damage.
So the life of a diabetic is basically monitoring their carbohydrate intake and then injecting an appropriate amount of insulin, based on a series of complex mathematical formulas, to match it. Too little and they go into ketosis. Too much insulin can drop their blood sugar dangerously low, which can lead to comas and death. Its a delicate tightrope that they walk every day.
The last few decades have seen advances in diabetes treatment that will blow your mind. To put them into context, lets rewind 50 years or so to look at what treatment was like.
Back in the day, a diabetic would wake up every morning and pee into a test tube. Theyd then drop a tablet into it that would change color to tell them what range their blood sugar was in high, normal or low. Theyd then take a single injection of long-lasting time-release insulin that would do for the entire day and hope for the best. When they were done, theyd take the syringe, boil it on the stove to sterilize it and put it back for tomorrow.
Needless to say, the life expectancy for diabetics was pretty short. Without a way to detect highs or lows, their bodies were at the mercy of a variety of factors and many died.
So there were two problems facing diabetics: being able to monitor blood sugar and being able to deliver the appropriate amount of insulin, no more, no less.
Monitoring got easier with the invention of the fingerprick blood glucose monitor in 1981. A drop of blood is introduced to an enzyme, and then an electrical current is passed through it. The number of electrons the sample loses correlates to the amount of glucose present in the sample. This allowed for significantly more precision, delivering a numerical representation of the patients current blood sugar.
That was coupled with the development of faster-acting insulin, so diabetics could treat highs as they happened. The next wave of diabetes care required them to be a more active participant in their management, checking glucose throughout the day and making adjustments as needed. As cool as this was, technology was about to get involved in a big way.
Fingerprick glucose is accurate but requires the diabetic to go through a process every time they want to check (and only works when theyre awake). The threat of low blood sugars at night is a very real one, as glucose levels can drop quickly. An accidental scientific discovery in the mid-1990s helped change the lives of diabetics around the world.
Researchers were experimenting with the bodys cell fluid in the skin and discovered that it basically mirrors the blood glucose level with about a 15-minute delay. In 1999, MiniMed got FDA approval for the first continuous glucose monitor an electrode thats inserted into a diabetics skin that transmits a reading every five minutes without the need to draw blood. Now patients could get real-time feedback on their blood sugar throughout the day. Those early sensors were good for about three days before the bodys immune system rejected them, but modern ones can go for a week or more before theyre changed.
Monitoring that accurate is all well and good, but a diabetic would still need to give themselves an injection to bring high blood sugar down. However, an earlier invention made that process significantly easier. In 1973, Dean Kamen (inventor of the Segway) debuted the worlds first wearable insulin pump, a device that could dose any amount of insulin to a diabetic through a cannula, or small tube, that attached to the body. This gave diabetics even more control over their treatment, enabling them to microdose and control exactly how much of the hormone they receive.
Pumps have advanced significantly over the last decade, with one the Omnipod not needing a tube at all, but affixing directly to the skin and communicating wirelessly with a control device. Patients who manage diabetes with these devices are uniformly in better condition, and even though only one in a thousand diabetics currently uses a pump, that number is rising.
The next step is the artificial pancreas, a device that combines the two into one. These have passed clinical trials and are being rolled out slowly by endocrinologists around the country. Using complex algorithms, they monitor blood glucose and treat it at the same time in a closed-loop system, also administering glucose when blood sugars are too low. Early results are incredibly positive. Like existing pumps and CGMs, they still have to be changed out regularly, but the system marks a significant advance in treatment.
The future of diabetes is even more exciting. Companies are working on insulin that doesnt have to be injected, but rather is absorbed through the skin with a sound-activated patch. Another brand can be inhaled before a meal. Google is collaborating with contact lens manufacturer Alcon on a lens that measures blood sugar through the eye.
So if you see somebody walking around with some little gray boxes attached to their arms or stomach, its highly possible that theyre toting around a cyborg pancreas, wired into the cloud and keeping them healthy.
See the original post here:
How Diabetes Is Transforming People Into Real-Life Cyborgs - Geek
- TRANSPLANT VIEWS: Stem cell therapy used for diabetic patients [Last Updated On: June 23rd, 2011] [Originally Added On: June 23rd, 2011]
- Diabetes - Video [Last Updated On: November 29th, 2011] [Originally Added On: November 29th, 2011]
- Stem Cell Treatment vs Diet For Diabetes - Video [Last Updated On: January 12th, 2012] [Originally Added On: January 12th, 2012]
- Orgenesis' Sarah Ferber, Ph.D on Using a Diabetes Patient's Own Liver Cells as a Novel Source of Insulin [Last Updated On: June 15th, 2012] [Originally Added On: June 15th, 2012]
- Diabetes drug may kill cancer stem cells, study says [Last Updated On: June 20th, 2012] [Originally Added On: June 20th, 2012]
- Diabetes reversed in mice using stem cells [Last Updated On: June 28th, 2012] [Originally Added On: June 28th, 2012]
- Diabetes Reversed In Mice Thanks To Stem Cell Transplant [Last Updated On: June 28th, 2012] [Originally Added On: June 28th, 2012]
- Diabetes Reversal In Mice Via Stem Cells [Last Updated On: June 28th, 2012] [Originally Added On: June 28th, 2012]
- Diabetes drug makes brain cells grow [Last Updated On: July 6th, 2012] [Originally Added On: July 6th, 2012]
- Diabetes drug helps brain growth, makes mice smarter [Last Updated On: July 6th, 2012] [Originally Added On: July 6th, 2012]
- Diabetes study hit by lack of funds [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Stem Cells Lupus Testimony Stem Alive - Video [Last Updated On: November 20th, 2012] [Originally Added On: November 20th, 2012]
- Common diabetes drug could fight ovarian cancer [Last Updated On: December 4th, 2012] [Originally Added On: December 4th, 2012]
- Diabetes distresses bone marrow stem cells by damaging their microenvironment [Last Updated On: February 1st, 2013] [Originally Added On: February 1st, 2013]
- Mike Maldonado uses exercise to fight Diabetes and Cancer - Video [Last Updated On: February 22nd, 2013] [Originally Added On: February 22nd, 2013]
- Diabetes : Deep-sea diving tank combined with stem cells to treat condition [Last Updated On: March 12th, 2013] [Originally Added On: March 12th, 2013]
- Diabetes team finds new hormone that could transform care [Last Updated On: April 25th, 2013] [Originally Added On: April 25th, 2013]
- Hormone Shows Potential as Diabetes Treatment in Mice [Last Updated On: April 27th, 2013] [Originally Added On: April 27th, 2013]
- Potential Diabetes Breakthrough - Video [Last Updated On: April 28th, 2013] [Originally Added On: April 28th, 2013]
- Stem Cell Therapy Cures Type 1 Diabetes in Mice [Last Updated On: June 7th, 2013] [Originally Added On: June 7th, 2013]
- John Chick: Giving diabetes the boot [Last Updated On: August 22nd, 2013] [Originally Added On: August 22nd, 2013]
- Scientists Create Personalized Stem Cells, Raising Hopes for Diabetes Cure [Last Updated On: April 28th, 2014] [Originally Added On: April 28th, 2014]
- Stem Cells from a Diabetes Patient [Last Updated On: April 28th, 2014] [Originally Added On: April 28th, 2014]
- Gut Cells May Be Coaxed to Make Insulin for People With Type 1 Diabetes [Last Updated On: July 1st, 2014] [Originally Added On: July 1st, 2014]
- Diabetes tipo 2 Podra ser reversible? [Last Updated On: July 31st, 2014] [Originally Added On: July 31st, 2014]
- James Shapiro: "Cutting Edge Islet and Stem Cell Transplant Therapies in the Clinic for Diabetes" - Video [Last Updated On: August 4th, 2014] [Originally Added On: August 4th, 2014]
- Cure for Type 1 diabetes imminent after Harvard stem-cell breakthrough [Last Updated On: October 9th, 2014] [Originally Added On: October 9th, 2014]
- New diabetes breakthrough 'bigger than the discovery of insulin' [Last Updated On: October 11th, 2014] [Originally Added On: October 11th, 2014]
- A cure for diabetes and awful jokes [Last Updated On: October 12th, 2014] [Originally Added On: October 12th, 2014]
- Stem Cell Success Raises Hopes of Type 1 Diabetes Cure [Last Updated On: October 12th, 2014] [Originally Added On: October 12th, 2014]
- Major step toward diabetes cure - Video [Last Updated On: October 12th, 2014] [Originally Added On: October 12th, 2014]
- Did Scientists Just Cure Type 1 Diabetes? - Video [Last Updated On: October 15th, 2014] [Originally Added On: October 15th, 2014]
- Muscle relaxant may treat rare form of diabetes, scientists find [Last Updated On: November 26th, 2014] [Originally Added On: November 26th, 2014]
- TESTIMONI LAMININE - Ginjal Diabetes dan Komplikasi - Video [Last Updated On: December 3rd, 2014] [Originally Added On: December 3rd, 2014]
- Laminine - Seminar Diabetes - Video [Last Updated On: December 5th, 2014] [Originally Added On: December 5th, 2014]
- Stem cells show promise for reversing type 2 diabetes [Last Updated On: March 19th, 2015] [Originally Added On: March 19th, 2015]
- Vitamin D prevents diabetes and clogged arteries in mice [Last Updated On: March 19th, 2015] [Originally Added On: March 19th, 2015]
- stemtech testimonial diabetes www afastemcell com - Video [Last Updated On: April 29th, 2015] [Originally Added On: April 29th, 2015]
- Afastemcell - testimoni penderita diabetes - Video [Last Updated On: April 29th, 2015] [Originally Added On: April 29th, 2015]
- Diabetes.net Welcome to the Original Diabetes Network [Last Updated On: May 9th, 2015] [Originally Added On: May 9th, 2015]
- Diabetes mellitus [Last Updated On: May 30th, 2015] [Originally Added On: May 30th, 2015]
- Type 2 Diabetes: Everything You Need to Know [Last Updated On: August 6th, 2015] [Originally Added On: August 6th, 2015]
- Diabetes Mellitus Center - Washington, DC - MedicineNet [Last Updated On: August 21st, 2015] [Originally Added On: August 21st, 2015]
- Washington, DC - American Diabetes Association [Last Updated On: August 21st, 2015] [Originally Added On: August 21st, 2015]
- Type 1 Diabetes: Causes, Tests, Symptoms and Treatments [Last Updated On: August 23rd, 2015] [Originally Added On: August 23rd, 2015]
- Type 2 Diabetes: Causes, Symptoms, Prevention, and More [Last Updated On: August 26th, 2015] [Originally Added On: August 26th, 2015]
- Diabetes mellitus - Wikipedia, the free encyclopedia [Last Updated On: August 27th, 2015] [Originally Added On: August 27th, 2015]
- Diabetes | Overview [Last Updated On: August 31st, 2015] [Originally Added On: August 31st, 2015]
- Virginia Diabetes and Endocrinology [Last Updated On: September 7th, 2015] [Originally Added On: September 7th, 2015]
- About Diabetes - American Heart Association [Last Updated On: September 8th, 2015] [Originally Added On: September 8th, 2015]
- Diabetes [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- NIHSeniorHealth: Diabetes - What is Diabetes? [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- Diabetes Symptoms: Common Symptoms of Diabetes [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- Type 2 Diabetes Condition Center - Health.com [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- Diabetes - Symptoms, Diagnosis, Treatment of Diabetes - NY ... [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- Raleigh North Carolina Office of the American Diabetes ... [Last Updated On: September 12th, 2015] [Originally Added On: September 12th, 2015]
- Louisiana Office of the American Diabetes Association [Last Updated On: September 21st, 2015] [Originally Added On: September 21st, 2015]
- Diabetes Basics - What is Diabetes? - Lifeclinic [Last Updated On: October 3rd, 2015] [Originally Added On: October 3rd, 2015]
- Kentucky: Cabinet for Health and Family Services - Diabetes [Last Updated On: October 3rd, 2015] [Originally Added On: October 3rd, 2015]
- Albuquerque-Santa Fe, New Mexico American Diabetes [Last Updated On: October 7th, 2015] [Originally Added On: October 7th, 2015]
- Chicago Illinois Office of the American Diabetes Association [Last Updated On: October 16th, 2015] [Originally Added On: October 16th, 2015]
- Wisconsin Diabetes Prevention and Control Program | Wisconsin ... [Last Updated On: October 25th, 2015] [Originally Added On: October 25th, 2015]
- Diabetes Basics [Last Updated On: July 25th, 2016] [Originally Added On: July 25th, 2016]
- Diabetes: Symptoms, Causes and Treatments - Health News [Last Updated On: July 25th, 2016] [Originally Added On: July 25th, 2016]
- What Can I Eat If I Have Diabetes [Last Updated On: August 1st, 2016] [Originally Added On: August 1st, 2016]
- JDRF Type 1 Diabetes Research Funding and Advocacy [Last Updated On: August 5th, 2016] [Originally Added On: August 5th, 2016]
- children with DIABETES Online Community [Last Updated On: August 5th, 2016] [Originally Added On: August 5th, 2016]
- WHO | Diabetes programme [Last Updated On: August 5th, 2016] [Originally Added On: August 5th, 2016]
- Bridgewater, New Jersey - American Diabetes Association [Last Updated On: August 14th, 2016] [Originally Added On: August 14th, 2016]
- Diabetes Prevention and Control - New Jersey [Last Updated On: August 17th, 2016] [Originally Added On: August 17th, 2016]
- NJDOH - Family Health services - New Jersey [Last Updated On: August 17th, 2016] [Originally Added On: August 17th, 2016]
- Diabetes Australia [Last Updated On: August 18th, 2016] [Originally Added On: August 18th, 2016]
- Diabetes Facts & Information | Joslin Diabetes Center [Last Updated On: August 23rd, 2016] [Originally Added On: August 23rd, 2016]
- Diabetes mellitus type 2 - Wikipedia, the free encyclopedia [Last Updated On: August 23rd, 2016] [Originally Added On: August 23rd, 2016]
- Diabetes - Better Health Channel [Last Updated On: August 23rd, 2016] [Originally Added On: August 23rd, 2016]
- Diabetes Symptoms: American Diabetes Association [Last Updated On: September 1st, 2016] [Originally Added On: September 1st, 2016]
- Types of Diabetes | NIDDK [Last Updated On: September 7th, 2016] [Originally Added On: September 7th, 2016]
- Diabetes mellitus - Wikipedia [Last Updated On: October 26th, 2016] [Originally Added On: October 26th, 2016]
- Diabetes May Be Warning Sign of Pancreatic Cancer - WebMD [Last Updated On: February 6th, 2017] [Originally Added On: February 6th, 2017]
- Roche won't sell diabetes businessit's looking for deals to boost it instead - FierceBiotech [Last Updated On: February 6th, 2017] [Originally Added On: February 6th, 2017]