SIOUX FALLS, S.D.--(BUSINESS WIRE)--SAB Biotherapeutics (SAB), a clinical-stage biopharmaceutical development company advancing a new class of immunotherapies, today announced that it has entered into multiple collaboration and option agreements with global biotherapeutics leader CSL Behring. The collaborations will explore the possibility and the potential of new therapies to treat challenging autoimmune, infectious and idiopathic diseases by leveraging SABs DiversitAb platform.
SAB has developed a unique platform, through advanced genetic engineering, to naturally and rapidly produce large amounts of human antibodies without using human donors.
The agreement includes a research program which will investigate a potential new source for human immunoglobulin G (IgG). Human IgG is currently used for a number of immunological and neurological diseases including Primary Immunodeficiency, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Guillain-Barre Syndrome (GBS), Immune Thrombocytopenic Purpura (ITP), and Multifocal Motor Neuropathy (MMN).
CSL Behring is a leader in the global immunoglobulins market, which has grown substantially over the last five years. Key factors fueling market growth include an aging population, increased emphasis on the diagnosis and treatment of immune diseases, and its increased use in new indications.
SAB Biotherapeutics has developed a very interesting and novel platform for the production of human immunoglobulins, said Dr. Andrew Nash, Senior Vice President, Research for CSL Behring. CSL Behring is committed to the continuous development of innovative therapies that address unmet needs for patients with rare and serious diseases. This collaboration will provide both companies an opportunity to explore the potential of these new approaches to positively impact areas of need.
CSL Behrings R&D footprint includes more than 1,700 scientists across the globe with an R&D investment exceeding $800 million in 2018 - 2019.
We are excited that CSL Behring has chosen to work with SAB Biotherapeutics to explore new immunotherapies leveraging our technology platform, said Dr. Eddie J. Sullivan, president, CEO and co-founder of SAB Biotherapeutics. We believe combining our unique human antibody development and production capabilities with CSL Behrings established immunoglobulin franchise and vast expertise in biopharmaceutical development will broaden therapeutic possibilities.
CSL Behring and SAB will share research program and related costs and plan to complete the initial phase in 2020. The collaboration may lead to subsequent development and commercialization agreements.
About SAB Biotherapeutics, Inc.
SAB Biotherapeutics, Inc. (SAB), headquartered in Sioux Falls, S.D. is a clinical-stage, biopharmaceutical development company advancing a new class of immunotherapies leveraging fully human polyclonal antibodies. Utilizing some of the most complex genetic engineering and antibody science in the world, SAB has developed the only platform that can rapidly produce natural, highly targeted, high-potency, immunotherapies at commercial scale. The company is advancing programs in autoimmunity, infectious diseases, inflammation and exploratory oncology.
Read the original post:
SAB Biotherapeutics Announces Research Collaboration With CSL Behring - Business Wire
- Genetic Engineering (excerpt) - Video [Last Updated On: January 9th, 2012] [Originally Added On: January 9th, 2012]
- Promising early results with therapeutic cancer vaccines [Last Updated On: February 16th, 2012] [Originally Added On: February 16th, 2012]
- Genetic Risk and Stressful Early Infancy Join to Increase Risk for Schizophrenia [Last Updated On: March 27th, 2012] [Originally Added On: March 27th, 2012]
- Innovative cell printing technologies hold promise for tissue engineering R&D [Last Updated On: March 28th, 2012] [Originally Added On: March 28th, 2012]
- SAGE® Labs Creates The First Tissue-Specific Gene Deletion In Rats [Last Updated On: April 21st, 2012] [Originally Added On: April 21st, 2012]
- Devangshu Datta: Towards an HIV cure [Last Updated On: May 5th, 2012] [Originally Added On: May 5th, 2012]
- Now *This* Is a Cell Phone: Using Radio Waves to Control Specific Genes in Mice | 80beats [Last Updated On: May 11th, 2012] [Originally Added On: May 11th, 2012]
- Genetic packing: Successful stem cell differentiation requires DNA compaction, study finds [Last Updated On: May 11th, 2012] [Originally Added On: May 11th, 2012]
- Premier issue of BioResearch Open Access launched by Mary Ann Liebert Inc. publishers [Last Updated On: May 17th, 2012] [Originally Added On: May 17th, 2012]
- GEN reports on growth of tissue engineering revenues [Last Updated On: July 11th, 2012] [Originally Added On: July 11th, 2012]
- New therapeutic target for prostate cancer identified [Last Updated On: July 18th, 2012] [Originally Added On: July 18th, 2012]
- Novel pig model may be useful for human cancer studies [Last Updated On: July 24th, 2012] [Originally Added On: July 24th, 2012]
- New gene therapy strategy boosts levels of deficient protein in Friedreich's ataxia [Last Updated On: July 25th, 2012] [Originally Added On: July 25th, 2012]
- Should high-dose interleukin-2 continue to be the treatment of choice for metastatic melanoma? [Last Updated On: July 26th, 2012] [Originally Added On: July 26th, 2012]
- New marker for identifying precursors to insulin-producing cells in pancreas [Last Updated On: August 22nd, 2012] [Originally Added On: August 22nd, 2012]
- 3D Biomatrix’s Perfecta3D® Hanging Drop Plates Featured in Prominent Life Science Journals [Last Updated On: October 1st, 2012] [Originally Added On: October 1st, 2012]
- Progress in Cell-SELEX compound screening technology reviewed in BioResearch Open Access [Last Updated On: October 18th, 2012] [Originally Added On: October 18th, 2012]
- Can the addition of radiolabeled treatments improve outcomes in advanced metastatic disease? [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]
- Is the detection of early markers of Epstein Barr virus of diagnostic value? [Last Updated On: November 18th, 2012] [Originally Added On: November 18th, 2012]
- Genetic Engineering Of Mesenchymal Stem Cells - Video [Last Updated On: November 18th, 2012] [Originally Added On: November 18th, 2012]
- Ramble: Simelweis Taboo - Video [Last Updated On: December 12th, 2012] [Originally Added On: December 12th, 2012]
- The Super Protein That Can Cut DNA and Revolutionize Genetic Engineering [Last Updated On: March 22nd, 2013] [Originally Added On: March 22nd, 2013]
- Cellular Dynamics International Expands MyCell Products Line with Disease Models, Genetic Engineering Patents [Last Updated On: June 5th, 2013] [Originally Added On: June 5th, 2013]
- World Stem Cell Summit to be presented by Genetics Policy Institute, Mary Ann Liebert, Inc., and Genetic Engineering ... [Last Updated On: June 11th, 2013] [Originally Added On: June 11th, 2013]
- Genetic engineering - Wikipedia, the free encyclopedia [Last Updated On: November 1st, 2013] [Originally Added On: November 1st, 2013]
- Genetic Engineering: What is Genetic Engineering? [Last Updated On: November 1st, 2013] [Originally Added On: November 1st, 2013]
- Critical factor (BRG1) identified for maintaining stem cell pluripotency [Last Updated On: February 7th, 2014] [Originally Added On: February 7th, 2014]
- Genome Surgery [Last Updated On: February 11th, 2014] [Originally Added On: February 11th, 2014]
- Engineering The Human Genome One Letter At A Time [Last Updated On: February 11th, 2014] [Originally Added On: February 11th, 2014]
- CRISPR is the technology that could allow researchers to perform microsurgery on genes [Last Updated On: February 15th, 2014] [Originally Added On: February 15th, 2014]
- Joseph Glorioso, Ph.D., receives Pioneer Award [Last Updated On: February 19th, 2014] [Originally Added On: February 19th, 2014]
- Commentary: field of tissue engineering is progressing at remarkable pace [Last Updated On: March 5th, 2014] [Originally Added On: March 5th, 2014]
- Pioneer Award recipients Marina Cavazzana and Adrian Thrasher recognized for advancing gene therapy to the clinic for ... [Last Updated On: March 24th, 2014] [Originally Added On: March 24th, 2014]
- New method yields potent, renewable human stem cells with promising therapeutic properties [Last Updated On: March 25th, 2014] [Originally Added On: March 25th, 2014]
- First evidence that very small embryonic-like stem cells [Last Updated On: April 2nd, 2014] [Originally Added On: April 2nd, 2014]
- Scarless wound healing -- applying lessons learned from fetal stem cells [Last Updated On: April 11th, 2014] [Originally Added On: April 11th, 2014]
- Novel marker discovered for stem cells derived from human umbilical cord blood [Last Updated On: April 18th, 2014] [Originally Added On: April 18th, 2014]
- GENs Top 10 Session Picks for the 2014 BIO International Convention [Last Updated On: May 2nd, 2014] [Originally Added On: May 2nd, 2014]
- A Vaccine for Heart Disease Could Mean No Pills, Lettuce or a Gym [Last Updated On: June 14th, 2014] [Originally Added On: June 14th, 2014]
- Gene editing tool can write HIV out of the picture [Last Updated On: June 22nd, 2014] [Originally Added On: June 22nd, 2014]
- Inner ear stem cells hold promise for restoring hearing [Last Updated On: June 24th, 2014] [Originally Added On: June 24th, 2014]
- New method to grow zebrafish embryonic stem cells can regenerate whole fish [Last Updated On: June 30th, 2014] [Originally Added On: June 30th, 2014]
- Novel methods may help stem cells survive transplantation into damaged tissues [Last Updated On: July 22nd, 2014] [Originally Added On: July 22nd, 2014]
- New method for reducing tumorigenicity in induced pluripotent stem-cell based therapies [Last Updated On: July 24th, 2014] [Originally Added On: July 24th, 2014]
- Malcolm K. Brenner receives Pioneer Award for advances in gene-modified T cells targeting cancer [Last Updated On: July 26th, 2014] [Originally Added On: July 26th, 2014]
- Conclusive evidence on role of circulating mesenchymal stem cells in organ injury [Last Updated On: August 22nd, 2014] [Originally Added On: August 22nd, 2014]
- New genomic editing methods produce better disease models from patient-derived iPSCs [Last Updated On: September 8th, 2014] [Originally Added On: September 8th, 2014]
- Tory Williams combats controversy surrounding stem cell therapy with new book [Last Updated On: September 11th, 2014] [Originally Added On: September 11th, 2014]
- NYIT Expert Predicts Growth in Demand for 3D Kidneys, Livers and Hearts [Last Updated On: December 9th, 2014] [Originally Added On: December 9th, 2014]
- The 'Berlin patient,' first and only person cured of HIV, speaks out [Last Updated On: January 6th, 2015] [Originally Added On: January 6th, 2015]
- Integrins are essential in stem cell binding to defective cartilage for joint regeneration [Last Updated On: January 27th, 2015] [Originally Added On: January 27th, 2015]
- Scientists urge caution in using new CRISPR technology to treat human genetic disease [Last Updated On: March 20th, 2015] [Originally Added On: March 20th, 2015]
- Scientists call for caution in using DNA-editing technology [Last Updated On: March 23rd, 2015] [Originally Added On: March 23rd, 2015]
- 'Ban DNA Editing Of Sperm And Eggs' [Last Updated On: March 23rd, 2015] [Originally Added On: March 23rd, 2015]
- Mount Sinai Researchers Discover Genetic Origins of Myelodysplastic Syndrome Using Stem Cells [Last Updated On: March 26th, 2015] [Originally Added On: March 26th, 2015]
- Researchers discover genetic origins of myelodysplastic syndrome using stem cells [Last Updated On: March 26th, 2015] [Originally Added On: March 26th, 2015]
- Pulling the strings of our genetic puppetmasters [Last Updated On: April 6th, 2015] [Originally Added On: April 6th, 2015]
- Going deep on life extension investments and human genetic engineering (Morning Read) [Last Updated On: April 6th, 2015] [Originally Added On: April 6th, 2015]
- Genetic engineering: a guide for kids by Tiki the Penguin [Last Updated On: July 8th, 2015] [Originally Added On: July 8th, 2015]
- genetic engineering | Britannica.com [Last Updated On: July 20th, 2015] [Originally Added On: July 20th, 2015]
- Interactives . DNA . Genetic Engineering [Last Updated On: August 3rd, 2015] [Originally Added On: August 3rd, 2015]
- Genetic engineering - Memory Alpha, the Star Trek Wiki [Last Updated On: September 10th, 2015] [Originally Added On: September 10th, 2015]
- Genetic Engineering Careers in India : How to become a ... [Last Updated On: September 10th, 2015] [Originally Added On: September 10th, 2015]
- Genetic Engineering (song) - Wikipedia, the free encyclopedia [Last Updated On: August 8th, 2016] [Originally Added On: August 8th, 2016]
- Genetic Engineering - BiologyMad [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- UNL's AgBiosafety for Educators [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- Recent Articles | Genetic Engineering | The Scientist ... [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- Human Genetic Engineering - Popular Issues [Last Updated On: October 29th, 2016] [Originally Added On: October 29th, 2016]
- Explore More: Genetic Engineering - iptv.org [Last Updated On: October 29th, 2016] [Originally Added On: October 29th, 2016]
- Genetic Engineering and GM Crops - Pocket K | ISAAA.org [Last Updated On: November 10th, 2016] [Originally Added On: November 10th, 2016]
- Pros and Cons of Genetic Engineering | HRFnd [Last Updated On: November 10th, 2016] [Originally Added On: November 10th, 2016]
- Genetic Engineering - The New York Times [Last Updated On: November 10th, 2016] [Originally Added On: November 10th, 2016]
- Genetic Engineering | MSPCA-Angell [Last Updated On: November 10th, 2016] [Originally Added On: November 10th, 2016]
- What is genetic engineering? - Definition from WhatIs.com [Last Updated On: November 10th, 2016] [Originally Added On: November 10th, 2016]
- Genetic Engineering in Agriculture | Union of Concerned ... [Last Updated On: November 16th, 2016] [Originally Added On: November 16th, 2016]
- Free genetic engineering Essays and Papers - 123helpme [Last Updated On: November 20th, 2016] [Originally Added On: November 20th, 2016]
- Gene therapy - Wikipedia [Last Updated On: November 20th, 2016] [Originally Added On: November 20th, 2016]
- Writing the human genome - The Biological SCENE [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- America's First Free-Roaming Genetically Engineered Insects Are ... - Gizmodo [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Stanford's Final Exams Pose Question About the Ethics of Genetic Engineering - Futurism [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]