Scarless wound healing — applying lessons learned from fetal stem cells

PUBLIC RELEASE DATE:

10-Apr-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, April 10, 2014In early fetal development, skin wounds undergo regeneration and healing without scar formation. This mechanism of wound healing later disappears, but by studying the fetal stem cells capable of this scarless wound healing, researchers may be able to apply these mechanisms to develop cell-based approaches able to minimize scarring in adult wounds, as described in a Critical Review article published in Advances in Wound Care, a monthly publication from Mary Ann Liebert, Inc., publishers and an Official Journal of the Wound Healing Society. The article is available free on the Advances in Wound Care website.

Michael Longaker, Peter Lorenz, and co-authors from Stanford University School of Medicine and John A. Burns School of Medicine, University of Hawaii, Honolulu, describe a new stem cell that has been identified in fetal skin and blood that may have a role in scarless wound healing. In the article "The Role of Stem Cells During Scarless Skin Wound Healing", the authors propose future directions for research to characterize the differences in wound healing mechanisms between fetal and adult skin-specific stem cells.

"This work comes from the pioneers in the field and delineates the opportunities towards scarless healing in adults," says Editor-in-Chief Chandan K. Sen, PhD, Professor of Surgery and Director of the Comprehensive Wound Center and the Center for Regenerative Medicine and Cell-Based Therapies at The Ohio State University Wexner Medical Center, Columbus, OH.

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About the Journal

Advances in Wound Care is a monthly journal published online and in print that reports the latest scientific discoveries, translational research, and clinical developments in acute and chronic wound care. Each issue provides a digest of the latest research findings, innovative wound care strategies, industry product pipeline, and developments in biomaterials and skin and tissue regeneration to optimize patient outcomes. The broad scope of applications covered includes limb salvage, chronic ulcers, burns, trauma, blast injuries, surgical repair, skin bioengineering, dressings, anti-scar strategies, diabetic ulcers, ostomy, bedsores, biofilms, and military wound care. Complete tables of content and a sample issue may be viewed on the Advances in Wound Care website.

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Scarless wound healing -- applying lessons learned from fetal stem cells