Bionano Genomics Announces Participation at the European Society of Human Genetics Conference (ESHG) 2022 Featuring OGM Across a Broad Range of…

Bionano Genomics

The Long String VANTAGE for DNA isolation, a collaborative development between Bionano and Hamilton, and the worlds first automation solution for Ultra High Molecular Weight (UHMW) extraction used in optical genome mapping (OGM), will be on display at the conference

A corporate satellite presentation by Dr. Detlef Trost, Laboratoire CERBA, and Dr. Alexander Hoischen, Radboud UMC, will cover the latest research on OGM for rare undiagnosed genetic disease (RUGD) discovery

Three featured scientific presentations, one each by Dr. Claudia Carvalho, Pacific Northwest Research Institute, Dr. LalaEl Khattabi, Hpital Cochin, and Dr. Kornelia Neveling, Radboud UMC, will cover the use of OGM in research on complex genomic rearrangement structures, characterization of structural variations (SVs), and on repeat expansion disorder testing, respectively

9 scientific poster presentations and e-posters will illustrate the application of Bionanos OGM solutions in constitutional disorders and RUGD diagnosis

SAN DIEGO, June 10, 2022 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (Nasdaq: BNGO) today announced its participation at theEuropean Society of Human Genetics (ESHG) 2022 Conference, with 13 scientific and poster presentations highlighting the application of OGM across rare undiagnosed genetic disease and genetic disorders. Additionally, Bionano and Hamilton will present the Long String VANTAGE, the worlds first automation solution for UHMW extraction used in OGM.

ESHG is an annual conference that brings together industry and academic professionals to discuss new technologies and advances in the field of human genetics. ESHG sessions will take placeJune 11-14, 2022 virtually and in Vienna, Austria.

Bionano and Hamilton jointly announced the Long String VANTAGE, which is the first Assay Ready Workstation solution in Hamiltons Long String Genomics product program which supports extraction of UHMW DNA at increased scale. Attendees at ESHG will be able to learn more about the Long String VANTAGE at both companies booths and can experience a demonstration of the workflow at Hamiltons booth throughout the conference.

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As part of a corporate satellite presentation, Dr. Detlef Trost from Laboratoire CERBA, and Dr. Alexander Hoischen from Radboud UMC, will share their latest research on OGM for RUGD.

Three genomics researchers will participate in separate featured scientific presentations, highlighting use of OGM in genetic disorder testing. Dr. Claudia Carvalho of the Pacific Northwest Research Institute will present on complex genomic rearrangement structures (CGRs) in neurodevelopmental disorders. Dr. LalaEl Khattabi will present on a recent study highlighting the OGM in the characterization of complex SVs. Dr. Kornelia Neveling from Radboud UMC will present on repeat expansion disorder testing using OGM.

Scientific presentations and poster sessions from Bionano and customers include:

Room

Title

Presenter

Presented

ACV, Room G, Level-2

See More, Know More: How OGM Provides Answers for Rare Undiagnosed Genetic Disease

Trost D., Hoischen A., Delpu Y.

June 11, 202210:00-11:30 CEST

Hall E-2, Concurrent Symposia S05

S05.2: Identification of Complex Genomic Rearrangement Structures in Disease

Carvalho C.

June 12, 20228:30-10:00 CEST

Hall E2-Workshop: Whats New in Cytogenomics?

W12: Optical Genome Mapping Enables Next-Generation Cytogenetics

El Khattabi L.

June 13, 202214:00-15:30 CEST

Hall E2- Concurrent Sessions C27

C27.3: Optical Genome Mapping for Repeat Expansion Disorder Testing

Neveling K.

June 14, 202211:00-12:30 CEST

Poster

Title

Author

Presented

P15.004.A

Structural and copy number variant detection, filtering, annotation, and classification by optical genome mapping in constitutional disorders

Delpu Y.

Poster Session June 12, 202213:00-14:00 CEST

P11.010.A

FSHD analysis pipeline by Bionano optical genome mapping: A field report

Heinrich U.

Poster Session June 12, 202213:00-14:00 CEST

P13.107.A

An insertion in the MSH2 gene detected by Bionano optical mapping and confirmed by Nanopore sequencing in a family with suspected Lynch Syndrome

Aalkken R.

Poster Session June 12, 202213:00-14:00 CEST

P09.027.C

Optical genome mapping analysis of FMR1 expansions in fragile X syndrome and multi-site validation

Venier A.

Poster Session June 13, 202212:45-13:45 CEST

P15.003.D

Comparative benchmarking of optical genome mapping and chromosomal microarray reveals high technological concordance in CNV identification and structural variant refinement

Jaber D.

Poster Session June 13, 202215:45-16:45 CEST

P16.020.D

Optical genome mapping in routine human genetic diagnostics: Lessons learned

Dremsek P.

Poster Session June 13, 202215:45-16:45 CEST

P16.032.D

Optical Genome Mapping as a diagnostic tool in cases of unresolved rare diseases

Trost D.

Poster Session June 13, 202215:45-16:45 CEST

EP15.018

A paracentric inversion that disrupts the SHANK2 gene resolved using cytogenomics

Huyghebaert J.

E-Poster

EP15.002

Recurrent constitutional chromosome five inversion revisited

Doco-Fenzy M.

E-Poster

More details on the conference can be found here.

We are thrilled to see the broad range of presentations featuring OGM at ESHG this year. These institutions and their research teams have conducted innovative research to help demonstrate the potential utility of OGM as a more sensitive, faster and less expensive alternative to traditional cytogenetics methods, commented Erik Holmlin, president and chief executive officer of Bionano. We are also excited for attendees to learn more about our collaboration with Hamilton and the Long String VANTAGE automation system. We believe this innovation can significantly reduce time to results, reduce hands on time and improve OGM performance by standardizing the process of UHMW DNA isolation, and we look forward to sharing more at ESHG.

About Bionano Genomics

Bionano Genomics is a provider of genome analysis solutions that can enable researchers and clinicians to reveal answers to challenging questions in biology and medicine. The Companys mission is to transform the way the world seesthe genome through OGM solutions, diagnostic services and software. The Company offers OGM solutions for applications across basic, translational and clinical research. Through its Lineagen business, the Company also provides diagnostic testing forpatients with clinical presentations consistent with autism spectrum disorder and other neurodevelopmental disabilities. Through its BioDiscovery business, the Companyalso offers an industry-leading, platform-agnostic software solution, which integratesnext-generation sequencing and microarray data designed to provide analysis, visualization, interpretation and reporting of copy number variants, single-nucleotide variants and absence of heterozygosity across the genome in one consolidated view.For more information, visit http://www.bionanogenomics.com, http://www.lineagen.comor http://www.biodiscovery.com

Forward-Looking Statements of Bionano Genomics

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as believe, potential, can, will, and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, the potential contribution of our OGM solutions to offer the anticipated benefits for and contributions to the areas reported in the presentations given and posters made available at the ESHG Annual Meeting; anticipated benefits and improvements resulting from the use of Long String VANTAGE to reliably and consistently isolate high quality and sufficient quantity of UHMW DNA for use with OGM . Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape and the introduction of competitive technologies or improvements to existing technologies; the ability of our OGM solutions to offer the anticipated benefits for and contributions to the areas of research reported in the presentations given and posters made available at the ESHG Annual Meeting; future study results contradicting the results reported in the presentations given and posters made available at the ESHG Annual Meeting; the ability of Long String VANTAGE system to reliably and consistently isolate high quality and sufficient quantity of UHMW DNA for use with OGM; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the Securities and Exchange Commission, including, without limitation, our Annual Report on Form 10-K for the year ended December 31, 2021 and in other filings subsequently made by us with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on managements assumptions and estimates as of such date. We do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

CONTACTSCompany Contact:Erik Holmlin, CEOBionano Genomics, Inc.+1 (858) 888-7610eholmlin@bionanogenomics.com

Investor Relations:Amy ConradJuniper Point+1 (858) 366-3243amy@juniper-point.com

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Bionano Genomics Announces Participation at the European Society of Human Genetics Conference (ESHG) 2022 Featuring OGM Across a Broad Range of...