TUMXUK, China In a dusty city in the Xinjiang region on Chinas western frontier, the authorities are testing the rules of science.
With a million or more ethnic Uighurs and others from predominantly Muslim minority groups swept up in detentions across Xinjiang, officials in Tumxuk have gathered blood samples from hundreds of Uighurs part of a mass DNA collection effort dogged by questions about consent and how the data will be used.
In Tumxuk, at least, there is a partial answer: Chinese scientists are trying to find a way to use a DNA sample to create an image of a persons face.
The technology, which is also being developed in the United States and elsewhere, is in the early stages of development and can produce rough pictures good enough only to narrow a manhunt or perhaps eliminate suspects. But given the crackdown in Xinjiang, experts on ethics in science worry that China is building a tool that could be used to justify and intensify racial profiling and other state discrimination against Uighurs.
In the long term, experts say, it may even be possible for the Communist government to feed images produced from a DNA sample into the mass surveillance and facial recognition systems that it is building, tightening its grip on society by improving its ability to track dissidents and protesters as well as criminals.
Some of this research is taking place in labs run by Chinas Ministry of Public Security, and at least two Chinese scientists working with the ministry on the technology have received funding from respected institutions in Europe. International scientific journals have published their findings without examining the origin of the DNA used in the studies or vetting the ethical questions raised by collecting such samples in Xinjiang.
In papers, the Chinese scientists said they followed norms set by international associations of scientists, which would require that the men in Tumxuk (pronounced TUM-shook) gave their blood willingly. But in Xinjiang, many people have no choice. The government collects samples under the veneer of a mandatory health checkup program, according to Uighurs who have fled the country. Those placed in internment camps two of which are in Tumxuk also have little choice.
The police prevented reporters from The New York Times from interviewing Tumxuk residents, making verifying consent impossible. Many residents had vanished in any case. On the road to one of the internment camps, an entire neighborhood had been bulldozed into rubble.
Growing numbers of scientists and human rights activists say the Chinese government is exploiting the openness of the international scientific community to harness research into the human genome for questionable purposes.
Already, China is exploring using facial recognition technology to sort people by ethnicity. It is also researching how to use DNA to tell if a person is a Uighur. Research on the genetics behind the faces of Tumxuks men could help bridge the two.
The Chinese government is building essentially technologies used for hunting people, said Mark Munsterhjelm, an assistant professor at the University of Windsor in Ontario who tracks Chinese interest in the technology.
In the world of science, Dr. Munsterhjelm said, theres a kind of culture of complacency that has now given way to complicity.
Sketching someones face based solely on a DNA sample sounds like science fiction. It isnt.
The process is called DNA phenotyping. Scientists use it to analyze genes for traits like skin color, eye color and ancestry. A handful of companies and scientists are trying to perfect the science to create facial images sharp and accurate enough to identify criminals and victims.
The Maryland police used it last year to identify a murder victim. In 2015, the police in North Carolina arrested a man on two counts of murder after crime-scene DNA indicated the killer had fair skin, brown or hazel eyes, dark hair, and little evidence of freckling. The man pleaded guilty.
Despite such examples, experts widely question phenotypings effectiveness. Currently, it often produces facial images that are too smooth or indistinct to look like the face being replicated. DNA cannot indicate other factors that determine how people look, such as age or weight. DNA can reveal gender and ancestry, but the technology can be hit or miss when it comes to generating an image as specific as a face.
Phenotyping also raises ethical issues, said Pilar Ossorio, a professor of law and bioethics at the University of Wisconsin-Madison. The police could use it to round up large numbers of people who resemble a suspect, or use it to target ethnic groups. And the technology raises fundamental issues of consent from those who never wanted to be in a database to begin with.
What the Chinese government is doing should be a warning to everybody who kind of goes along happily thinking, How could anyone be worried about these technologies? Dr. Ossorio said.
With the ability to reconstruct faces, the Chinese police would have yet another genetic tool for social control. The authorities have already gathered millions of DNA samples in Xinjiang. They have also collected data from the hundreds of thousands of Uighurs and members of other minority groups locked up in detention camps in Xinjiang as part of a campaign to stop terrorism. Chinese officials have depicted the camps as benign facilities that offer vocational training, though documents describe prisonlike conditions, while testimonies from many who have been inside cite overcrowding and torture.
Even beyond the Uighurs, China has the worlds largest DNA database, with more than 80 million profiles as of July, according to Chinese news reports.
If I were to find DNA at a crime scene, the first thing I would do is to find a match in the 80 million data set, said Peter Claes, an imaging specialist at the Catholic University of Leuven in Belgium, who has studied DNA-based facial reconstruction for a decade. But what do you do if you dont find a match?
Though the technology is far from accurate, he said, DNA phenotyping can bring a solution.
To unlock the genetic mysteries behind the human face, the police in China turned to Chinese scientists with connections to leading institutions in Europe.
One of them was Tang Kun, a specialist in human genetic diversity at the Shanghai-based Partner Institute for Computational Biology, which was founded in part by the Max Planck Society, a top research group in Germany.
The German organization also provided $22,000 a year in funding to Dr. Tang because he conducted research at an institute affiliated with it, said Christina Beck, a spokeswoman for the Max Planck Society. Dr. Tang said the grant had run out before he began working with the police, according to Dr. Beck.
Another expert involved in the research was Liu Fan, a professor at the Beijing Institute of Genomics who is also an adjunct assistant professor at Erasmus University Medical Center in the Netherlands.
Both were named as authors of a 2018 study on Uighur faces in the journal Hereditas (Beijing), published by the government-backed Chinese Academy of Sciences. They were also listed as authors of a study examining DNA samples taken last year from 612 Uighurs in Tumxuk that appeared in April in Human Genetics, a journal published by Springer Nature, which also publishes the influential journal Nature.
Both papers named numerous other authors, including Li Caixia, chief forensic scientist at the Ministry of Public Security.
In an interview, Dr. Tang said he did not know why he was named as an author of the April paper, though he said it might have been because his graduate students worked on it. He said he had ended his affiliation with the Chinese police in 2017 because he felt their biological samples and research were subpar.
To be frank, you overestimate how genius the Chinese police is, said Dr. Tang, who had recently shut down a business focused on DNA testing and ancestry.
Like other geneticists, Dr. Tang has long been fascinated by Uighurs because their mix of European and East Asian features can help scientists identify genetic variants associated with physical traits. In his earlier studies, he said, he collected blood samples himself from willing subjects.
Dr. Tang said the police approached him in 2016, offering access to DNA samples and funding. At the time, he was a professor at the Partner Institute for Computational Biology, which is run by the Chinese Academy of Sciences but was founded in 2005 in part with funding from the Max Planck Society and still receives some grants and recommendations for researchers from the German group.
Dr. Beck, the Max Planck spokeswoman, said Dr. Tang had told the organization that he began working with the police in 2017, after it had stopped funding his research a year earlier.
But an employment ad on a government website suggests the relationship began earlier. The Ministry of Public Security placed the ad in 2016 seeking a researcher to help explore the DNA of physical appearance traits. It said the person would report to Dr. Tang and to Dr. Li, the ministrys chief forensic scientist.
Dr. Tang did not respond to additional requests for comment. The Max Planck Society said Dr. Tang had not reported his work with the police as required while holding a position at the Partner Institute, which he did not leave until last year.
The Max Planck Society takes this issue very seriously said will ask its ethics council to review the matter, Dr. Beck said.
It is not clear when Dr. Liu, the assistant professor at Erasmus University Medical Center, began working with the Chinese police. Dr. Liu says in his online rsum that he is a visiting professor at the Ministry of Public Security at a lab for on-site traceability technology.
In 2015, while holding a position with Erasmus, he also took a post at the Beijing Institute of Genomics. Two months later, the Beijing institute signed an agreement with the Chinese police to establish an innovation center to study cutting-edge technologies urgently needed by the public security forces, according to the institutes website.
Dr. Liu did not respond to requests for comment.
Erasmus said that Dr. Liu remained employed by the university as a part-time researcher and that his position in China was totally independent of the one in the Netherlands. It added that Dr. Liu had not received any funding from the university for the research papers, though he listed his affiliation with Erasmus on the studies. Erasmus made inquiries about his research and determined there was no need for further action, according to a spokeswoman.
Erasmus added that it could not be held responsible for any research that has not taken place under the auspices of Erasmus by Dr. Liu, even though it continued to employ him.
Still, Dr. Lius work suggests that sources of funding could be mingled.
In September, he was one of seven authors of a paper on height in Europeans published in the journal Forensic Science International. The paper said it was backed by a grant from the European Union and by a grant from Chinas Ministry of Public Security.
Dr. Tang said he was unaware of the origins of the DNA samples examined in the two papers, the 2018 paper in Hereditas (Beijing) and the Human Genetics paper published in April. The publishers of the papers said they were unaware, too.
Hereditas (Beijing) did not respond to a request for comment. Human Genetics said it had to trust scientists who said they had received informed consent from donors. Local ethics committees are generally responsible for verifying that the rules were followed, it said.
Springer Nature said on Monday that it had strengthened its guidelines on papers involving vulnerable groups of people and that it would add notes of concern to previously published papers.
In the papers, the authors said their methods had been approved by the ethics committee of the Institute of Forensic Science of China. That organization is part of the Ministry of Public Security, Chinas police.
With 161,000 residents, most of them Uighurs, the agricultural settlement of Tumxuk is governed by the powerful Xinjiang Production and Construction Corps, a quasi-military organization formed by decommissioned soldiers sent to Xinjiang in the 1950s to develop the region.
The state news media described Tumxuk, which is dotted with police checkpoints, as one of the gateways and major battlefields for Xinjiangs security work.
In January 2018, the town got a high-tech addition: a forensic DNA lab run by the Institute of Forensic Science of China, the same police research group responsible for the work on DNA phenotyping.
Procurement documents showed the lab relied on software systems made by Thermo Fisher Scientific, a Massachusetts company, to work with genetic sequencers that analyze DNA fragments. Thermo Fisher announced in February that it would suspend sales to the region, saying in a statement that it had decided to do so after undertaking fact-specific assessments.
For the Human Genetics study, samples were processed by a higher-end sequencer made by an American firm, Illumina, according to the authors. It is not clear who owned the sequencer. Illumina did not respond to requests for comment.
The police sought to prevent two Times reporters from conducting interviews in Tumxuk, stopping them upon arrival at the airport for interrogation. Government minders then tailed the reporters and later forced them to delete all photos, audio and video recordings taken on their phones in Tumxuk.
Uighurs and human rights groups have said the authorities collected DNA samples, images of irises and other personal data during mandatory health checks.
In an interview, Zhou Fang, the head of the health commission in Tumxuk, said residents voluntarily accepted free health checks under a public health program known as Physicals for All and denied that DNA samples were collected.
Ive never heard of such a thing, he said.
The questions angered Zhao Hai, the deputy head of Tumxuks foreign affairs office. He called a Times reporter shameless for asking a question linking the health checks with the collection of DNA samples.
Do you think America has the ability to do these free health checks? he asked. Only the Communist Party can do that!
Visit link:
China Uses DNA to Map Faces, With Help From the West - The New York Times
- Seattle Genetics Reports Fourth Quarter and Year 2011 Financial Results [Last Updated On: February 13th, 2012] [Originally Added On: February 13th, 2012]
- Seattle Genetics Loss Narrows; But Stock Down - Update [Last Updated On: February 14th, 2012] [Originally Added On: February 14th, 2012]
- Seattle Genetics Highlights Updated Survival Data from ADCETRIS® Pivotal Trial in Patients with Relapsed or Refractory ... [Last Updated On: June 15th, 2012] [Originally Added On: June 15th, 2012]
- A Growth-Free Quarter -- and That's OK [Last Updated On: August 11th, 2012] [Originally Added On: August 11th, 2012]
- Seattle Genetics and Millennium Complete Enrollment in Phase III AETHERA Trial of ADCETRIS® for Post-Transplant ... [Last Updated On: September 25th, 2012] [Originally Added On: September 25th, 2012]
- ORF Genetics to Offer endotoxin- and Animal-free FGFb and mLIF for Stem Cell Research [Last Updated On: October 4th, 2012] [Originally Added On: October 4th, 2012]
- FAQ-4 of 19: What Chance That Stem Cells Will Help Me When I Get Stem Cell Therapy - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- FAQ-4 of 19: What Is My Chance of Success With Stem Cells in Stem Cell Therapy - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- FAQ-3 of 19 -How Do Stem Cells Work in Stem Cell Therapy? - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- Stem Cell Therapy for osteoarthritis Cosmetic Surgery Thailand Review - Urban Beauty Thailand - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- [RMS] C-Class Stem Cell Processing Center (SPC) - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- FAQ-4 19- What Chances for Stem Cell Success When I Get Stem Cell Therapy? - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- FAQ-4 19- What Chance Stem Cells Can Help Me After Stem Cell Therapy? - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- Is stem cell therapy really effective? - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- STEM CELL THERAPY cure HIV patient - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- Seattle Genetics Announces ADCETRIS® Receives European Commission Conditional Marketing Authorization [Last Updated On: November 6th, 2012] [Originally Added On: November 6th, 2012]
- Seattle Genetics Highlights ADCETRIS® (Brentuximab Vedotin) Data in Relapsed Hodgkin Lymphoma and Other CD30-Positive ... [Last Updated On: December 13th, 2012] [Originally Added On: December 13th, 2012]
- Seattle Genetics Highlights Data Presentations from Genentech ADC Collaborator Programs at ASH Annual Meeting [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Seattle Genetics Highlights Next Generation Antibody-Drug Conjugate SGN-CD33A at ASH Annual Meeting [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Clinical Data from NewLink Genetics' HyperAcute Prostate Cancer Immunotherapy Published in Journal of Immunotherapy [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Seattle Genetics Announces Data from Investigator-Sponsored Trials of ADCETRIS® (Brentuximab Vedotin) in Cutaneous T ... [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Seattle Genetics Reports Data from Phase I Trial of ADCETRIS® (Brentuximab Vedotin) in Front-line Hodgkin Lymphoma at ... [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Seattle Genetics to test possible new Adcetris use [Last Updated On: December 16th, 2012] [Originally Added On: December 16th, 2012]
- Myriad Genetics to Present at the 2013 J.P. Morgan Annual Healthcare Conference [Last Updated On: December 18th, 2012] [Originally Added On: December 18th, 2012]
- Data From SGEN on Cancer Candidate [Last Updated On: January 30th, 2013] [Originally Added On: January 30th, 2013]
- Health Canada Approves ADCETRIS® (Brentuximab Vedotin) for the Treatment of Relapsed or Refractory Hodgkin Lymphoma ... [Last Updated On: February 2nd, 2013] [Originally Added On: February 2nd, 2013]
- Canada Approves Seattle Genetics' Adcetris [Last Updated On: February 5th, 2013] [Originally Added On: February 5th, 2013]
- Canada Approves Seattle Genetics' Adcetris - Analyst Blog [Last Updated On: February 5th, 2013] [Originally Added On: February 5th, 2013]
- ADC Data from Seattle Genetics [Last Updated On: April 11th, 2013] [Originally Added On: April 11th, 2013]
- Genetics of alcoholism research [Last Updated On: April 16th, 2013] [Originally Added On: April 16th, 2013]
- Genetics Policy Institute and univerCELLmarket to co-publish 360 – the Free Newsletter Covering Stem Cells and ... [Last Updated On: April 29th, 2013] [Originally Added On: April 29th, 2013]
- Genetics Policy Institute and univerCELLmarket to co-publish 360 – the Free Newsletter Covering Stem Cells and ... [Last Updated On: May 2nd, 2013] [Originally Added On: May 2nd, 2013]
- Genetics Policy Institute Opens Washington, D.C. Office [Last Updated On: May 7th, 2013] [Originally Added On: May 7th, 2013]
- Seattle Genetics Announces Initiation of Phase 1/2 Trial of ADCETRIS® (Brentuximab Vedotin) in Combination with ... [Last Updated On: June 11th, 2013] [Originally Added On: June 11th, 2013]
- Seattle Genetics Announces Initiation of Phase 1/2 Trial of ADCETRIS® (Brentuximab Vedotin) in Combination with ... [Last Updated On: June 17th, 2013] [Originally Added On: June 17th, 2013]
- Takeda and Seattle Genetics Highlight Post-Hoc Analysis Examining Progression-free Survival with ADCETRIS® ... [Last Updated On: June 19th, 2013] [Originally Added On: June 19th, 2013]
- Seattle Genetics Highlights ADCETRIS® (Brentuximab Vedotin) Clinical Data at International Conference on Malignant ... [Last Updated On: June 22nd, 2013] [Originally Added On: June 22nd, 2013]
- SGEN/Astellas to Co-Develop Another ADC [Last Updated On: June 30th, 2013] [Originally Added On: June 30th, 2013]
- Life Stem Genetics is Pleased to Announce That It Has Completed the First $500,000 Private Placement of the Recently ... [Last Updated On: October 22nd, 2013] [Originally Added On: October 22nd, 2013]
- Life Stem Genetics Strengthens Its Executive Advisory Board by Adding MBAs Matthew Sullivan and Shahab Bakhtyar [Last Updated On: October 29th, 2013] [Originally Added On: October 29th, 2013]
- Seattle Genetics, Inc. Posts Record Adcetris Sales [Last Updated On: October 31st, 2014] [Originally Added On: October 31st, 2014]
- Inbreeding - Wikipedia, the free encyclopedia [Last Updated On: May 9th, 2015] [Originally Added On: May 9th, 2015]
- Genetics of Colorectal Cancer - National Cancer Institute [Last Updated On: July 16th, 2015] [Originally Added On: July 16th, 2015]
- Seattle Genetics: Advancing Antibody-Drug Conjugates for ... [Last Updated On: August 18th, 2015] [Originally Added On: August 18th, 2015]
- genetics | Britannica.com [Last Updated On: August 25th, 2015] [Originally Added On: August 25th, 2015]
- Genetics and Genetic Disorders and Diseases - WebMD [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Genetics - Biology [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Genetics: MedlinePlus Medical Encyclopedia [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Genetics of Skin Cancer - National Cancer Institute [Last Updated On: September 13th, 2015] [Originally Added On: September 13th, 2015]
- Genetics in Georgia | New Georgia Encyclopedia [Last Updated On: September 15th, 2015] [Originally Added On: September 15th, 2015]
- Faculty & Staff | Directory | Medical Partnership [Last Updated On: October 5th, 2015] [Originally Added On: October 5th, 2015]
- Genetics | Learn Science at Scitable [Last Updated On: October 12th, 2015] [Originally Added On: October 12th, 2015]
- Genetics - Wikipedia, the free encyclopedia [Last Updated On: October 15th, 2015] [Originally Added On: October 15th, 2015]
- Department of Genetics || University of Pennsylvania [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Genetics News - Genetics Science, Genetics Technology, Genetics [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Home > Genetics | Yale School of Medicine [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Ology Genetics - AMNH [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- About Genetics | Understanding Genetics [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Genetics | Article about genetics by The Free Dictionary [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Genetics - Simple English Wikipedia, the free encyclopedia [Last Updated On: October 21st, 2015] [Originally Added On: October 21st, 2015]
- Cell Size and Scale - Learn Genetics [Last Updated On: September 24th, 2016] [Originally Added On: September 24th, 2016]
- Genetics of Prostate Cancer (PDQ)Health Professional ... [Last Updated On: September 24th, 2016] [Originally Added On: September 24th, 2016]
- Genetics of Skin Cancer (PDQ)Health Professional Version ... [Last Updated On: September 24th, 2016] [Originally Added On: September 24th, 2016]
- Basic Genetics [Last Updated On: September 26th, 2016] [Originally Added On: September 26th, 2016]
- genetics facts, information, pictures | Encyclopedia.com ... [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- Genetics - Wikipedia [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- How culture, passion and genetics are fueling a Nigerian takeover of US sports - CBS sports.com (blog) [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- After vote, Accelerated Genetics slated to merge - La Crosse Tribune [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Autism genetics, explained | Spectrum | Autism Research News - Spectrum [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- The problematics of genetics and the Aryan issue - The Hindu [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- North American genetics take centre stage in Wicklow - Agriland [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Genetics may lie at the heart of crop yield limitation - Phys.org - Phys.Org [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Research in genetics promises a long-term cure to diseases : Tony Mira, CEO at Ajuba International LLC - ETHealthworld.com [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- NewLink Genetics to Host Its Second Quarter 2017 Financial Results Conference Call on July 28, 2017 - GlobeNewswire (press release) [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Immunotherapy drug targets tumor's genetics instead of body part - Monroe Evening News [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Getting tumors tested for genetics is the latest theory to help drugs target cancer - The Denver Post [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Konica Minolta, With Eye on Health Care, Nears Deal for US Genetics Firm - New York Times [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Memphis Researchers Planning Big Upgrades to Online Genetics Database - Memphis Daily News [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Mosaic (genetics) - Simple English Wikipedia, the free ... [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Is There a Genetic Limit to Milk Production? - Dairy Herd Management [Last Updated On: July 11th, 2017] [Originally Added On: July 11th, 2017]