In the last century, the Western world has increased its emphasis on effort, talent, and achievement. This opened up opportunities for more people to climb the social ladder in search of a better life. A wider accessibility to an improved educational system in the last century has increased social mobility and has advanced the freedom of many to choose how and where to live. Yet, social inequalities are now growing and social mobility has reportedly been stalling since the 1990s in the richer countries of the world.
An unintended side effect of merit-based social mobility is that it stimulates selective migration; people with a higher education are more likely to move to regions that offer better living conditions and professional opportunities. This brain drain may be increasing inequalities between regions. There are large regional inequalities in wealth and health within Great Britain, and in the last 30 years, regional educational inequalities have reportedly grown.
A study from one of us (A.A.) published in Nature Human Behaviourtoday (October 21) shows that these regional inequalities have a genetic component that is becoming stronger over time. Data on about 450,000 British people of European descent illustrate that people who have more genetic variants linked to higher levels of education are on average more likely to live in wealthier areas of Great Britain, whereas people who have fewer of these variants are on average more likely to live in regions that have faced economic challenges, such as coal mining regions.
Regional differences in genes linked to education are just as much in line with some political differences, the study revealed, as with health and economic outcomes.
The study reveals that these regional genetic differences have been increasing due to migration: people are more likely to leave the poorer regions of the country if they are born with a genetic predisposition for higher educational attainment.
It is not exactly clear yet why these genes are linked to educational attainment; possibly through biological processes that influence traits such as intelligence, perseverance, and industriousness, but also partly because genes that are linked to a higher education are more common in children born to parents with a higher education. These parents tend to have more resources to provide better learning environments for their children, and environmental influences matter for educational outcomes.
Health outcomes such as obesity or diabetes show similar differences between richer and poorer regions. Our study found that these regional health differences could be better explained by environmental influences, such as the amount of fast food restaurants, than by regional differences in genetics. In other words, our chances of living a healthy life are not only influenced by our genes, but are also by where we live.
An unequal distribution of opportunities, benefits, and living circumstances across the country are a potent source for collective frustrations. The five poorest regions in Northern Europe are reportedly all in Great Britain, while the richest region is in London. It is not hard to imagine how the growing regional gap in wealth and health can be fertile ground for growing political differences. People increasingly live in different worlds. Regional differences in genes linked to education are just as much in line with some political differences, the study revealed, as with health and economic outcomes.
Our analyses also looked at regional differences in past and recent general election outcomes and the Brexit referendum. The regional clustering of genes linked to lower education was most strongly in line with votes for parties opposed to the political status quo, namely votes for the UK Independent Party and Brexit Leave votes, similar to previously reported educationally based voting patterns. People who did not vote in 2015 and 2016 were also more likely to come from regions with a higher prevalence of variants linked to lower education than people who did not vote in 1970.
The reward system of our society is based on the ideal that we can improve our lives by climbing the social ladder through our achievements. This type of merit-based social mobility is a good catalyst for societal progress in societies that are fair, as it can motivate people from all social strata to maximize their potential. When social class is regionally bound, however, this meritocratic system can result in migration flows that can exacerbate regional inequalities at a deeper level and lead to a decrease in social mobility.
In search of a solution to this complex problem, we think a good place to start is improving the living conditions of the poorer regions. The current conditions stimulate outwards migration, worse health outcomes, and likely worse educational outcomes as well. If these regional differences in living circumstances remain, the brain drain will continue and regional inequality will deepen. The economic and political unrest that follows will probably be felt across the entire country and beyond.
Abdel Abdellaouiis a population geneticist & behavioral geneticist at the Amsterdam University Medical Centers, whereJudy Luigjesis a neuroscientist.
Original post:
Opinion: The Nature of Social Inequalities in Great Britain - The Scientist
- Multiple neurodevelopmental disorders have a common molecular cause [Last Updated On: October 9th, 2014] [Originally Added On: October 9th, 2014]
- Human Longevity, Inc. Hires Industry Experts Barry Merriman, Ph.D., and Paul Mola, M.S. to Lead New Global Solutions ... [Last Updated On: October 31st, 2014] [Originally Added On: October 31st, 2014]
- Scientists create artificial human eggs and sperm [Last Updated On: December 27th, 2014] [Originally Added On: December 27th, 2014]
- What if the severity of our seasonal influenza were related to our genetic background? [Last Updated On: March 27th, 2015] [Originally Added On: March 27th, 2015]
- UCLA Human Genetics [Last Updated On: October 1st, 2015] [Originally Added On: October 1st, 2015]
- Human Genetics - Estrella Mountain Community College [Last Updated On: October 1st, 2015] [Originally Added On: October 1st, 2015]
- Human genetics - Wikipedia, the free encyclopedia [Last Updated On: October 29th, 2015] [Originally Added On: October 29th, 2015]
- Human genetics - An Introduction to Genetic Analysis ... [Last Updated On: November 2nd, 2015] [Originally Added On: November 2nd, 2015]
- Home Institute for Human Genetics at UCSF [Last Updated On: November 3rd, 2015] [Originally Added On: November 3rd, 2015]
- National Human Genome Research Institute [Last Updated On: August 8th, 2016] [Originally Added On: August 8th, 2016]
- Genetics - Smithsonian's Human Origins Program [Last Updated On: November 23rd, 2016] [Originally Added On: November 23rd, 2016]
- Toddler's Hair Stands Up Like Troll Doll Thanks To Rare Genetic Condition - HuffPost [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Can genetics play a role in education and well-being? - USC News [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Genetic variant linked to osteoarthritis favored in cold climates - Scope (blog) [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Human Evolution: Africa Exodus Made Homo Sapiens Shorter and Gave Them Arthritis - Newsweek [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Dispute Over British Baby's Fate Draws In Pope and US President - New York Times [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Human mitochondrial genetics - Wikipedia [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Using Big Data to Hack Autism - Scientific American [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- This Study Could Help Extend the Human Lifespan - Futurism [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Evolution and war: The 'deep roots' theory of human violence - Genetic Literacy Project [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Human Genetics | Pitt Public Health | University of Pittsburgh [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- human genetics | biology | Britannica.com [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- The Era of Human Gene Editing Is HereWhat Happens Next Is Critical - Singularity Hub [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- In US first, scientists edit genes of human embryos - Indiana Gazette [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- A protein involved in Alzheimer's disease may also be implicated in cognitive abilities in children - Medical Xpress [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Genome Sequencing Shows Spiders, Scorpions Share Ancestor - R & D Magazine [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Mindful of eugenics' dark history, researchers are reexamining the genetics of social mobility - Quartz [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Shrinking Bat DNA and Elastic Genomes - Quanta Magazine [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Bacteria May Rig Their DNA to Speed Up Evolution - WIRED [Last Updated On: August 19th, 2017] [Originally Added On: August 19th, 2017]
- Will Gene Editing Allow Us to Rid the World of Diseases? - Healthline [Last Updated On: August 19th, 2017] [Originally Added On: August 19th, 2017]
- Genes causing intellectual disabilities identified - The Indian Express [Last Updated On: September 3rd, 2017] [Originally Added On: September 3rd, 2017]
- Split-brain fruit fly research gives insight into autism - Nevada Today [Last Updated On: September 3rd, 2017] [Originally Added On: September 3rd, 2017]
- Human Genetics - McGill University [Last Updated On: August 18th, 2018] [Originally Added On: August 18th, 2018]
- Human Genetics - medschool.ucla.edu [Last Updated On: October 6th, 2018] [Originally Added On: October 6th, 2018]
- Department of Human Genetics | The University of Chicago [Last Updated On: October 6th, 2018] [Originally Added On: October 6th, 2018]
- Human genetic clustering - Wikipedia [Last Updated On: November 3rd, 2018] [Originally Added On: November 3rd, 2018]
- Mitochondrial Eve - Wikipedia [Last Updated On: November 18th, 2018] [Originally Added On: November 18th, 2018]
- Human Genetics - McGraw-Hill Education [Last Updated On: November 18th, 2018] [Originally Added On: November 18th, 2018]
- Human Genetics | Biomedical Sciences Graduate Program [Last Updated On: December 1st, 2018] [Originally Added On: December 1st, 2018]
- Human Genetics | Michigan Medicine | University of Michigan [Last Updated On: December 24th, 2018] [Originally Added On: December 24th, 2018]
- Human behaviour genetics - Wikipedia [Last Updated On: February 11th, 2019] [Originally Added On: February 11th, 2019]
- Human Genetics and Embryology - Open Access Journals [Last Updated On: February 11th, 2019] [Originally Added On: February 11th, 2019]
- Marshfield Clinic Research Institute - Welcome to The ... [Last Updated On: March 9th, 2019] [Originally Added On: March 9th, 2019]
- Human Genetic Modification | Center for Genetics and Society [Last Updated On: April 25th, 2019] [Originally Added On: April 25th, 2019]
- Humanized Liver Mice Model Market Emerging Niche Segments and Regional Markets - Commerce Gazette [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Short Sleeper Syndrome: When You Can Get By on Just a Few Hours of Sleep - The Crux - Discover Magazine [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Ceremony honors 2019 GASD hall inductees - The Recorder [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Genes, the social environment and adolescent smoking - Princeton University [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- LSU researcher looking at 'miracle drug' metformin as potential weapon against breast cancer - NOLA.com [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- The next omics? Tracking a lifetime of exposures to better understand disease - Knowable Magazine [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- 'Rejuvenation treatment can delay onset of heart diseases, cancer' - Down To Earth Magazine [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Global Human Genetics Market Report, History and Forecast 2014-2025, Breakdown Data by Companies, Key Regions, Types and Application - Market Industry... [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- DNA Found in 70000-Year-Old Pinky Bone Gives 1st Glimpse of Ancient Human Relative - Inside Edition [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Scientists release genetically altered mosquitoes to fight malaria - Global News [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Scientists Release Sterile Mosquitoes in Burkina to Fight Malaria - News18 [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Genes implicated in bipolar disorder identified - The Hindu [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Genetics and Justice: DNA Identification Technologies in Post-Dictatorial Argentina - KCPW [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- When Did Humans Reach North America? The Question Keeps Growing More Complex - The Crux - Discover Magazine [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Early postnatal overnutrition sets the body on a fast-track to aging - Baylor College of Medicine News [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Oxford Nanopore signs CRISPR licence - Life Sciences Intellectual Property Review [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Medical student with rare disease finds possible cure from studying his own blood samples - Fox News [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Study Gives the Green Light to the Fruit Fly's Color Preference - Nature World News [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Genetics CRISPR enters its first human trials - Science News for Students [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Lakin Named Finalist In Global Science Video Contest - My veronanj [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- The Genetic Origins of Sex Differences in Disease - Yale News [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- Human Genetics Market 2019 Growing with Major Key Player QIAGEN, Agilent Technologies, Thermo Fisher Scientific, Illumina, Promega, LabCorp, GE, etc -... [Last Updated On: September 22nd, 2019] [Originally Added On: September 22nd, 2019]
- The Complicated Truth About That Controversial 'Gay Gene' Study - Out Magazine [Last Updated On: September 27th, 2019] [Originally Added On: September 27th, 2019]
- Government launches 'UMMID' initiative to tackle inherited genetic diseases of new born ba - 5 Dariya News [Last Updated On: September 27th, 2019] [Originally Added On: September 27th, 2019]
- 1400-year-old Pictish Remains Finally Unearthed in Scotland - Ancient Origins [Last Updated On: September 27th, 2019] [Originally Added On: September 27th, 2019]
- GSK and AstraZeneca's PARP Inhibitors Will Flex Their Muscles at ESMO - BioSpace [Last Updated On: September 27th, 2019] [Originally Added On: September 27th, 2019]
- What Do Dairy Cows' Y Chromosomes Have to Do with Young Earth Creationism? Plenty. - Patheos [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- New books explore why dogs and humans have such a special bond - Science News [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- We need to understand the culture of whales so we can save them - Dal News [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- New Research on Climate Change and the Brain, the Relationship Between Stroke and Dementia, Advances in Epilepsy and MS Among the Brain Health... [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- This is Why Gene Editing of Plants and Animals Needs to be Regulated - In These Times [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- What's Behind Rise Of STDS Among Young People?: Epidemic Alarms Health Officials As Prevention Funding Drops - Kaiser Health News [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- Hacking Darwin: How the coming genetics revolution will play out - New Atlas [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- New research on climate change and the brain among the brain health initiatives unveiled at 24th World Congress of Neurology - WFN News [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- Overthinking Can Shorten Your Life, Says New Study - International Business Times [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]
- DNA research holds the keys to human history but it's being weaponized by politicians - Haaretz [Last Updated On: October 22nd, 2019] [Originally Added On: October 22nd, 2019]