What is a Stem Cell? What are autologous adult stem cells? How do adult stem cells work? What conditions are most helped by Stem Cell Therapy? Are there any known side effects to Adult Stem Cell Therapy? How long is the procedure? How long will it be before I see results? Is the procedure FDA approved? Are there any moral issues associated with Adult Stem Cell Therapy? Where is the best source of stem cells for therapy and treatment? Do you offer Bone Marrow Harvesting? What is Regenerative Medicine? Can Stem Cells Cause Cancer? Can Stem Cells Be Used in Patients that have or have had Cancer? How are Stem Cells Administered to the Patient? What claims are you currently making about what stem cell therapy can do for you? Is anything added to the stem cells? Does a patient have to participate in an IRB study and does a patient have to qualify for the IRB study to get treatment? What is a Stem Cell?
Stem cells are unspecialized cells but can give rise to almost any type of specialized cell in the human body. The environment in which the stem cell finds itself determines what kind of specialized cell the stem cell will become. In the example of placing the stem cells inside of a disc, they turn into cells that will rebuild the disc. PM&R Associates uses adult stem cells that only have the ability to turn into tissues such as cartilage and connective tissue as is found in spinal discs and joints, tendons, muscle, and ligaments. All of these tissues can be repaired with stem cells and to a lesser extent platelets. The cells are taken from your own body and used for treatment the same day, so there is no risk of rejection or disease transmission. These procedures are performed in our clinic, under conscious sedation and local anesthesia. This procedure is not currently covered by any insurance company. Most patients are helped by injecting a chondroitin and glucosamine mixture into the disc. This procedure is covered if an insurance company covers a discogram procedure. The results are dependent on there being live disc cells inside the disc
Autologous adult stem cells are derived from the same individuals body. Adult stem cells are undifferentiated cells, found throughout the body after development and do not have many of the properties of embryonic stem cells that, as the name implies, come from the embryo. Although adult stem cells can form other cells, they cannot form a new person and are not associated with the kind of cancers associated with embryonic stem cells. Stem cells are the fundamental elements of life that can be found in all tissues of the body: connective tissues, muscle tissues, nervous tissues, and epithelial tissues. In living tissue, adipose (fat) tissue has the highest concentration of stem cells and can produce billions of cells that will repair, replenish, and rejuvenate ones body immediately.
Adult stem cells are undifferentiated cells, found throughout the human body, that form after growth & development. The main purpose of adult stem cells is to use cell division to repair and replace dying cells in order to regenerate damaged tissue. Once adult stem cells are administered to the body, they respond to inflammatory signals secreted by damaged cells.
Although many clinics use stem cells to treat a wide variety of systemic conditions, at PM&R Associates we only treat musculoskeletal (MSK) conditions. These are primarily degenerative disc disease and osteoarthritis. Other MSK conditions would also respond, but usually less costly alternatives exist.
Side effects from stem cell therapy are related to the harvesting of the tissues that provide the stem cells and the procedure itself, not the stem cells. This is true as long as all of the blood cells are removed from the stem cells because the blood cells produce the pain associated with stem cell therapy. All of the cells can be removed from adipose derived stem cells but not from bone marrow derived stem cells.
Both the liposuction and bone marrow aspiration take about 30 minutes. Processing the adipose tissue takes about 40 minutes and the disc injection procedure takes between 30 and 45 minutes. A joint injection takes only a few minutes. You will be in the clinic about 2 hours, but we ask you to plan 3 hours in case there are unforeseen problems.
Stem cells are a biologic treatment. It takes time for the biologic response to take effect, so the longer you wait, the better the result. We do not expect to see significant results before two months.
No stem cell therapy is FDA approved, even the use of stem cells to treat certain forms of cancer. The FDA has decided that they will not interfere as long as the stem cells are not altered and are used the same day. Not altered means the stem cells cannot be cultured to increase their numbers. By using adipose (fat) tissue as the source, enough stem cells are obtained so that culturing is not necessary.
The controversies associated with stem cell therapy are associated with embryonic stem cells. Stem Cells used during treatment come from your own body. PM&R Associates does not harvest embryonic stem cells and is therefore not related to any controversial debates.
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