CAMBRIDGE, Mass.--(BUSINESS WIRE)--GV20 Therapeutics, a biopharmaceutical company using cutting-edge genomics and artificial intelligence approaches to discover next-generation cancer therapeutics, announced three key executive appointments to accelerate its growth and transition into a clinical-stage company. Pioneering cancer researcher and co-founder Shirley Liu, Ph.D. was named the Chief Executive Officer; former executive at Shape Pharmaceuticals and Tensha Therapeutics, Steven Landau, M.D., became the Chief Medical Officer; and Genentech veteran Ying Gong, Ph.D. was appointed Chief Business Officer.
Shirley Liu is an innovative and prolific computational cancer biologist. Having been on the faculty at the Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health for almost 20 years, she has made significant contributions to the understanding of gene regulation and drug response in cancer. Dr. Liu and Ted Xiao, Ph.D., a former postdoctoral fellow at Dana-Farber Cancer Institute and Harvard Medical School, co-founded GV20 Therapeutics in 2016 with the goal of applying high-throughput genomics and computational approaches to the discovery and development of novel cancer drugs. The companys efforts have led to the identification of novel targets and drug candidates including its first candidate, XBH25, a novel NK checkpoint inhibitor targeting solid tumors. GV20 expects to file an IND for XBH25 in the second half of 2022.
We are excited to welcome Steve and Ying and their expertise to the GV20 team, said CEO Shirley Liu. Ying and Steve both bring a wealth of experience advancing innovative oncology pipelines and building high-performing teams. That Ying and Steve have chosen to help lead GV20 at this crucial inflection point speaks to the power of our drug discovery capabilities and the potential of our pipeline. With their leadership, we are excited to advance XBH25 toward the clinic, and to discover more promising candidates at speed and scale with our integrated STEAD genomics and AI platform. We are well-positioned to bring next-generation immunotherapies to cancer patients.
ABOUT SHIRLEY LIU, PH.D.
Shirley Liu, Ph.D., co-founded GV20 Therapeutics in 2016 and joined the company full-time as the CEO in 2022. A highly cited cancer researcher, Dr. Liu was previously a Professor of Biostatistics and Computational Biology at Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health, and the co-director of the Center for Functional Cancer Epigenetics at Dana-Farber. With more than 250 peer-reviewed publications, her research has refined the understanding of hormone receptor therapies, epigenetic inhibitors, gamma-secretase inhibitors, receptor tyrosine kinase inhibitors, and immune checkpoint inhibitors in different cancers. She is a fellow of the International Society of Computational Biology (ISCB), American Institute for Medical and Biological Engineering (AIMBE), and was a Breast Cancer Research Foundation Investigator (2017-2021). Liu is a recipient of the Sloan Research Fellowship (2008), Weitzman Outstanding Early Career Investigator Award from the Endocrine Society (2016), ISCB Innovator Award (2020), and the Benjamin Franklin Award for Open Access in the Life Sciences (2020). Dr. Liu received her Ph.D. in Biomedical Informatics and Ph.D. minor in Computer Science from Stanford.
ABOUT STEVEN LANDAU, M.D.
Steven Landau, M.D., has more than 25 years of experience developing products for the treatment of cancers and inflammatory diseases, including the FDA-approved monoclonal antibody Entyvio. He has previously served as Chief Medical Officer at oncology-focused companies including Shape Pharmaceuticals and Tensha Therapeutics. Dr. Landau has also supported product development at OraVax, LeukoSite, Millennium Pharmaceuticals, and Praecis Pharmaceuticals. Dr. Landau earned his M.D. from Case Western Reserve University, and completed his post-graduate training at the Beth Israel Hospital and the Brigham and Women's Hospital in Boston.
ABOUT YING GONG, PH.D.
Ying Gong, Ph.D., is an experienced strategist, drug developer and team leader. Most recently, she served as Project Team Leader for oncology at Genentech, where she led drug development programs and business development projects from late-stage research to clinical proof-of-concept. Dr. Gong also served as Senior Director of Portfolio Strategy and Planning, shaping Genentech's industry-leading R&D strategy. Prior to that, she held roles in medical affairs, market access, global product strategy, and market planning at Genentech and Roche, and worked on a broad range of projects including new indication launches of Perjeta and Avastin. She began her career as a management consultant at Bain & Company. Dr. Gong earned a Ph.D. in Biochemistry and Molecular Biophysics from the California Institute of Technology, and an M.A. in Molecular Genetics from Smith College.
ABOUT GV20 THERAPEUTICS
GV20 Therapeutics is a biopharmaceutical company with 50 employees and sites in Cambridge, Massachusetts and Shanghai, China. The company closed a series B financing led by Coatue Management in October 2021. GV20 uses high-throughput functional genomics and artificial intelligence to identify novel cancer immunology drug targets and antibody therapeutics. The companys pipeline includes XBH25, a novel NK checkpoint inhibitor targeting solid tumors, which is currently progressing toward the clinic. GV20 references one of the most important acupoints for the human body, symbolizing the companys mission to find and exploit vulnerabilities in cancer biology.
To learn more about GV20, please visit https://gv20tx.com/ and follow the company on LinkedIn and Twitter.
- Silicon Biosystems to Present Single-Circulating Tumor Cell Molecular Characterization at the Fourth World CTC Summit [Last Updated On: April 26th, 2012] [Originally Added On: April 26th, 2012]
- Protein could be key for drugs that promote bone growth [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- Study sheds light on genetic 'clock' in embryonic cells [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]
- Study involving twin sisters provides clues for battling aggressive cancers [Last Updated On: February 9th, 2014] [Originally Added On: February 9th, 2014]
- Clues for battling aggressive cancers from twin sisters study [Last Updated On: February 11th, 2014] [Originally Added On: February 11th, 2014]
- Genetic cause found for premature ovarian failure [Last Updated On: March 6th, 2014] [Originally Added On: March 6th, 2014]
- Rutgers' Human Genetics Institute Wins $19 Million Federal Contract [Last Updated On: May 15th, 2014] [Originally Added On: May 15th, 2014]
- Elsevier Publishes Four New Books in Microbiology Portfolio [Last Updated On: November 13th, 2014] [Originally Added On: November 13th, 2014]
- Disease, Evolution, Neurology, and Drugs: Fruit Fly Research Continues to Teach Us About Human Biology [Last Updated On: February 28th, 2015] [Originally Added On: February 28th, 2015]
- "Big Brain" Gene Allowed for Evolutionary Expansion of Human Neocortex [Last Updated On: March 8th, 2015] [Originally Added On: March 8th, 2015]
- Director Molecular Genetics jobs in Rtp at LabCorp [Last Updated On: June 1st, 2015] [Originally Added On: June 1st, 2015]
- Molecular Genetics definition of Molecular Genetics in the ... [Last Updated On: June 4th, 2015] [Originally Added On: June 4th, 2015]
- molecular and human genetics | Momentum - The Baylor ... [Last Updated On: June 19th, 2015] [Originally Added On: June 19th, 2015]
- Molecular evolution - Wikipedia, the free encyclopedia [Last Updated On: July 16th, 2015] [Originally Added On: July 16th, 2015]
- The Rockefeller University Laboratory of Molecular Genetics [Last Updated On: July 21st, 2015] [Originally Added On: July 21st, 2015]
- Microbiology & Molecular Genetics - Rutgers New Jersey ... [Last Updated On: September 5th, 2015] [Originally Added On: September 5th, 2015]
- Clinical Genetics Congress | Clinical Genetics 2016 ... [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- Molecular genetics - Wikipedia, the free encyclopedia [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- Molecular Genetics - DNA, RNA, & Protein [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- MCW: Microbiology and Molecular Genetics Department [Last Updated On: October 21st, 2016] [Originally Added On: October 21st, 2016]
- Newcastle Hospitals - Molecular Genetics [Last Updated On: October 21st, 2016] [Originally Added On: October 21st, 2016]
- Molecular evolution - Wikipedia [Last Updated On: October 23rd, 2016] [Originally Added On: October 23rd, 2016]
- Molecular Genetics (Stanford Encyclopedia of Philosophy) [Last Updated On: October 30th, 2016] [Originally Added On: October 30th, 2016]
- Molecular Genetics - mmrl.edu [Last Updated On: November 12th, 2016] [Originally Added On: November 12th, 2016]
- Molecular biology - Wikipedia [Last Updated On: November 12th, 2016] [Originally Added On: November 12th, 2016]
- Human Molecular Genetics - amazon.com [Last Updated On: November 12th, 2016] [Originally Added On: November 12th, 2016]
- Molecular Genetics Service - Great Ormond Street Hospital ... [Last Updated On: November 16th, 2016] [Originally Added On: November 16th, 2016]
- The Passions of Nazneen Rahman - San Francisco Classical Voice [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- Genetic Testing for the Healthy - Harvard Medical School (registration) [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- Fundraising page set up in memory of Nottingham's Maid Marian - Nottingham Post [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- Dogs have their day at conference - Otago Daily Times [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- GGC Graduates Two from Medical Genetics Training Program - Index-Journal [Last Updated On: July 2nd, 2017] [Originally Added On: July 2nd, 2017]
- Irvine-based CombiMatrix in $33 million merger deal with Bay Area genetics firm - OCRegister [Last Updated On: August 7th, 2017] [Originally Added On: August 7th, 2017]
- First of 10 expected BJC Investigators named - Washington University School of Medicine in St. Louis [Last Updated On: August 7th, 2017] [Originally Added On: August 7th, 2017]
- Madhuri Hegde, PhD is Elected to the Board of the ACMG Foundation for Genetic and Genomic Medicine - Markets Insider [Last Updated On: August 7th, 2017] [Originally Added On: August 7th, 2017]
- Getting the word out: Seminar, walk put spotlight on Sickle Cell disease - Dothan Eagle [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- Out of a fish gut study, researchers open new doors in intestinal health - Durham Herald Sun [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- Gene-Silencing Finding May Lead to Better Understanding of Some ... - Genetic Engineering & Biotechnology News [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- Molecular Genetics and Genomics Program - Wake Forest ... [Last Updated On: October 1st, 2017] [Originally Added On: October 1st, 2017]
- Genetics and Molecular Biology | Peer Reviewed Journal [Last Updated On: June 30th, 2018] [Originally Added On: June 30th, 2018]
- Leeds Genetics Laboratory - Leeds Teaching Hospitals NHS Trust [Last Updated On: July 17th, 2018] [Originally Added On: July 17th, 2018]
- Genetics and Molecular Biology Research - iMedPub [Last Updated On: August 2nd, 2018] [Originally Added On: August 2nd, 2018]
- Molecular Genetics | ARUP Laboratories [Last Updated On: August 7th, 2018] [Originally Added On: August 7th, 2018]
- Molecular Genetics - The Ohio State University [Last Updated On: August 21st, 2018] [Originally Added On: August 21st, 2018]
- Peer Reviewed Genetics and Molecular Biology Journals ... [Last Updated On: September 5th, 2018] [Originally Added On: September 5th, 2018]
- Department of Microbiology and Molecular Genetics [Last Updated On: October 7th, 2018] [Originally Added On: October 7th, 2018]
- Molecular Genetics Jobs, Employment | Indeed.com [Last Updated On: October 10th, 2018] [Originally Added On: October 10th, 2018]
- Genomic Career: Molecular Geneticist ($35,620-$101,030) [Last Updated On: October 10th, 2018] [Originally Added On: October 10th, 2018]
- Molecular Genetics, Biochemistry & Microbiology [Last Updated On: October 10th, 2018] [Originally Added On: October 10th, 2018]
- Molecular Genetics | Department of Pediatrics [Last Updated On: December 1st, 2018] [Originally Added On: December 1st, 2018]
- Graduate Molecular Genetics - University of Toronto [Last Updated On: January 25th, 2019] [Originally Added On: January 25th, 2019]
- Molecular Genetics - OCME - nyc.gov [Last Updated On: February 19th, 2019] [Originally Added On: February 19th, 2019]
- Molecular Genetics - University of Toronto [Last Updated On: March 6th, 2019] [Originally Added On: March 6th, 2019]
- Department of Microbiology, Immunology and Molecular Genetics [Last Updated On: March 13th, 2019] [Originally Added On: March 13th, 2019]
- Molecular Genetics and Cell Biology [Last Updated On: May 4th, 2019] [Originally Added On: May 4th, 2019]
- Molecular Reproduction, Development and Genetics at IISc [Last Updated On: May 18th, 2019] [Originally Added On: May 18th, 2019]
- Molecular genetics | biology | Britannica.com [Last Updated On: September 7th, 2019] [Originally Added On: September 7th, 2019]
- BCH N of 1 Trial Yields Approved Therapy for Single Rare Disease Patient - Clinical OMICs News [Last Updated On: October 13th, 2019] [Originally Added On: October 13th, 2019]
- 5 habits of highly successful entrepreneurs revealed - GrowthBusiness.co.uk [Last Updated On: October 13th, 2019] [Originally Added On: October 13th, 2019]
- Leading by example: how AquaBounty, Oxford Biomedica, and Berkeley Lights have successfully brought products to market - SynBioBeta [Last Updated On: October 13th, 2019] [Originally Added On: October 13th, 2019]
- Blue Devil of the Week: Searching for Answers in the Genetic Code - Duke Today [Last Updated On: October 13th, 2019] [Originally Added On: October 13th, 2019]
- New Viruses Found in Farmed and Wild Salmon - Hakai Magazine [Last Updated On: October 13th, 2019] [Originally Added On: October 13th, 2019]
- Veterinary Molecular Diagnostics Market to Reach at a CAGR of 8.48% by 2026 With NEOGEN CORPORATION , Thermo Fisher Scientific, Inc., Virbac, General... [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Quantabio to Showcase Industry's Fastest qPCR-based NGS Library Quantification Kit and HiFi PCR Mix at American Society of Human Genetics Annual... [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Top Researchers to Present Discoveries Made Possible by Bionanos Saphyr System for Genome Imaging Technology at the ASHG 2019 Annual Meeting - Yahoo... [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Bionano Genomics Announces Adoption of Its Saphyr System by Clinical Cytogenetics Groups in Academia and Industry to Replace Traditional Methods for... [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Racial Disparities In NIH R01 Funding May Be Partly Caused By Topic Choice : Shots - Health News - NPR [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Denison presents: 'Christianity, Race, and the Haunting of the Biomedical Sciences' - The Newark Advocate [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- This image shows the aftermath of two galaxies colliding - CTV News [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Meet The Cast of Charmed Season 2 - TVOvermind [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Inherited Learning? It Happens, but How Is Uncertain - Quanta Magazine [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Where do Canada's federal parties stand on research funding? - Varsity [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- The double bind faced by black research applicants - University World News [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Excessive Brain Activity Linked to Shorter Life Span - PsychCentral.com [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- World Renowned Experts Appointed to Skyhawk Therapeutics Scientific Advisory Board - PRNewswire [Last Updated On: October 21st, 2019] [Originally Added On: October 21st, 2019]
- Lupus Study Illustrates the Importance of Diversity in Genetic Research - Nature World News [Last Updated On: October 30th, 2019] [Originally Added On: October 30th, 2019]
- Interpace to Present Data at the ATA Annual Meeting - GlobeNewswire [Last Updated On: October 30th, 2019] [Originally Added On: October 30th, 2019]
- Pacific subspecies of fin whales has been revealed by new genetic study - Oceanographic - Oceanographic Magazine [Last Updated On: October 30th, 2019] [Originally Added On: October 30th, 2019]
- Genetic Study: Shared Molecular Pathway Might Influence Susceptibility to Lack of Oxygen Caused by Sleep-disordered Breathing and Other Lung Illnesses... [Last Updated On: October 30th, 2019] [Originally Added On: October 30th, 2019]
- ERT to Treat Pompe May Work Better in Combo with Blood Pressure Medication, Study Says - Pompe Disease News [Last Updated On: October 30th, 2019] [Originally Added On: October 30th, 2019]