Licorice root and black licorice candy. A licorice-derived substance may have anti-inflammatory and anti-cancer effects.
Licorice is more than a candy people either love or hate it may play a role in preventing or treating certain types of cancer, according to researchers at the University of Illinois Chicago.
Gnanasekar Munirathinam and his research team are studying substances derived from the licorice plant Glycyrrhiza glabra to determine if they could be used to prevent or stop the growth of prostate cancer. Munirathinam is an associate professor in the department of biomedical sciences at the College of Medicine Rockford.
A research review into molecular insights of a licorice-derived substance called glycyrrhizin for preventing or treating cancer conducted by Dr. Munirathinam and student researchers suggests further research could lead to specific agents for clinical use.
The journal Pharmacological Research recently published the study titled Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights.
When we look at the research out there and our own data, it appears that glycyrrhizin and its derivative glycyrrhetinic acid have great potential as anti-inflammatory and anti-cancer agents, Munirathinam said. More research is needed into exactly how these could best be used to develop therapies, but this appears to be a promising area of cancer research.
Should everyone go out and eat a bunch of licorice? Probably not, because it may affect blood pressure, interact with certain medications, and cause serious adverse effects, including death, when used excessively. An occasional sweet treat of licorice candy or tea may be better options until more studies can show how to best harness the plants benefits.
Very few clinical trials in humans have been conducted, Munirathinam said. We hope our research on prostate cancer cells advances the science to the point where therapies can be translated to help prevent or even cure prostate and other types of cancer.
Reference: Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights by Rifika Jain, Mohamed Ali Hussein, Shannon Pierce, Chad Martens, Preksha Shahagadkar and Gnanasekar Munirathinam, 19 February 2022, Pharmacological Research.DOI: 10.1016/j.phrs.2022.106138
College of Medicine Rockford students Rifika Jain, Mohamed Ali Hussein, Preksha Shahagadkar, Shannon Pierce and Chad Martens are co-authors of the review, which was partly supported by the National Institutes of Health (R0CA227218) and Brovember Inc.
Originally posted here:
Substance Derived From Licorice May Have Anti-Inflammatory and Anti-Cancer Effects - SciTechDaily
- Living with Lupus: Hematopoietic Stem Cell Therapy for Lupus [Last Updated On: September 24th, 2011] [Originally Added On: September 24th, 2011]
- Unlocking the Secrets of Blod Cell Therapy - Video [Last Updated On: October 14th, 2011] [Originally Added On: October 14th, 2011]
- Alzheimers Neurons Created from Pluripotent Stem Cells [Last Updated On: January 28th, 2012] [Originally Added On: January 28th, 2012]
- Verastem to Present at Molecular Medicine Tri-Conference Symposium “Targeting Cancer Stem Cells in Oncology” [Last Updated On: February 16th, 2012] [Originally Added On: February 16th, 2012]
- Plethora of New Products to be Showcased at 2012 Molecular Medicine Tri-Conference [Last Updated On: February 18th, 2012] [Originally Added On: February 18th, 2012]
- Leukaemia cells have a remembrance of things past [Last Updated On: April 26th, 2012] [Originally Added On: April 26th, 2012]
- Science Translational Medicine and the DMM Global Foundation Announce Days of Molecular Medicine 2012 "The ... [Last Updated On: July 13th, 2012] [Originally Added On: July 13th, 2012]
- Common RNA pathway found in ALS and dementia [Last Updated On: October 1st, 2012] [Originally Added On: October 1st, 2012]
- Culprits behind ALS and dementia share common pathway [Last Updated On: October 2nd, 2012] [Originally Added On: October 2nd, 2012]
- 22 Molecular Medicine—Cloning and Stem Cells - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- Stem Cells and the Future of Medicine - Larry Goldstein, Ph.D. at TEDxAmericasFinestCity - Video [Last Updated On: November 1st, 2012] [Originally Added On: November 1st, 2012]
- Program in Molecular Medicine - UMass Medical School ... [Last Updated On: September 26th, 2016] [Originally Added On: September 26th, 2016]
- Molecular medicine - Wikipedia, the free encyclopedia [Last Updated On: September 26th, 2016] [Originally Added On: September 26th, 2016]
- Department of Molecular Medicine - College of Veterinary ... [Last Updated On: September 26th, 2016] [Originally Added On: September 26th, 2016]
- Molecular Medicine - Graduate School of Biomedical ... [Last Updated On: September 26th, 2016] [Originally Added On: September 26th, 2016]
- Home - Weatherall Institute of Molecular Medicine [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- Molecular Medicine - Wake Forest Baptist Health [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- Cellular and Molecular Medicine Graduate Program [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- International Masters Program Molecular Medicine ... [Last Updated On: October 20th, 2016] [Originally Added On: October 20th, 2016]
- LSUHSC School of Medicine - Biochemistry and Molecular Biology [Last Updated On: November 20th, 2016] [Originally Added On: November 20th, 2016]
- Molecular Medicine | Molecular Medicine Reports ... [Last Updated On: November 20th, 2016] [Originally Added On: November 20th, 2016]
- Precision medicine opens the door to scientific wellness preventive approaches to suicide - Medical Xpress [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- New Hampshire biologist reacts to gene-editing discovery - The Union Leader [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- The Human Heart May Have a Natural 'Backup Battery' - Healthline [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- Georgia colleges gear up for new semester - AJC.com - Atlanta Journal Constitution [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- Change in protein production essential to muscle function - Baylor College of Medicine News (press release) [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- Clinical trial uses a genetically engineered virus to fight cancer - Medical Xpress [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- A New Gene Editing Technique Could Finally Allow Us to Treat ALS - Futurism [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]
- New Version of CRISPR Corrects RNA Defects Linked to ... - Technology Networks [Last Updated On: August 16th, 2017] [Originally Added On: August 16th, 2017]
- Circular RNA Linked to Brain Function - Technology Networks [Last Updated On: August 16th, 2017] [Originally Added On: August 16th, 2017]
- Yenepoya University to offer biotech skill enhancement programme - Hindu Business Line [Last Updated On: August 16th, 2017] [Originally Added On: August 16th, 2017]
- Spotlight Innovation Enters into Sponsored Research Agreement with Indiana University to Develop New Therapies for ... - PR Newswire (press release) [Last Updated On: August 16th, 2017] [Originally Added On: August 16th, 2017]
- Using barcodes to trace cell development - Medical Xpress [Last Updated On: August 16th, 2017] [Originally Added On: August 16th, 2017]
- What can genetic testing really tell you? - Popular Science [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- Cancer Treatment Centers of America and Foundation Medicine Join Forces to Advance Precision Cancer Treatment - Markets Insider [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- A New Method of 3D Printing Living Tissues - Technology Networks [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- Spotlight Innovation Enters into Sponsored Research Agreement with Indiana University to Develop New Therapies for ... - Markets Insider [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- MS in Molecular Medicine - Drexel University College of ... [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- Master of Science (MSc) in Molecular Medicine - NTNU [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- Molecular Medicine Research - Wake Forest School of Medicine [Last Updated On: August 17th, 2017] [Originally Added On: August 17th, 2017]
- New method for the 3D printing of living tissues - Scientist Live [Last Updated On: August 22nd, 2017] [Originally Added On: August 22nd, 2017]
- Bio-inspired Materials Give Boost to Regenerative Medicine - Bioscience Technology [Last Updated On: August 22nd, 2017] [Originally Added On: August 22nd, 2017]
- MSU Expanding Medical Research In Grand Rapids | WKAR - WKAR [Last Updated On: August 30th, 2017] [Originally Added On: August 30th, 2017]
- Stabilizing TREM2 a potential strategy to combat Alzheimer's disease - Medical Xpress [Last Updated On: August 30th, 2017] [Originally Added On: August 30th, 2017]
- TCI woman fell 31 floors, due to work in molecular medicine in Malaysia - Magnetic Media (press release) [Last Updated On: August 30th, 2017] [Originally Added On: August 30th, 2017]
- Molecular Medicine | University of Maryland School of Medicine [Last Updated On: August 30th, 2017] [Originally Added On: August 30th, 2017]
- Reconstructing life at its beginning, cell by cell - Phys.Org [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- Dr. Pawel Muranski to Head New Cellular Immunotherapy Laboratory at NewYork-Presbyterian/Columbia University ... - Newswise (press release) [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- Hofstra and Northwell rename medical school following $61 million donation - The Island Now [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- TREM2 Cleavage Site Pinpointed: A Gateway to New Therapies? - Alzforum [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- The Secret Ingredient That Stops Honeybees From Becoming Queens - New York Times [Last Updated On: August 31st, 2017] [Originally Added On: August 31st, 2017]
- What happened to precision medicine? - Phoenix Business Journal [Last Updated On: September 4th, 2017] [Originally Added On: September 4th, 2017]
- Fetal genes can increase the risk of illness during pregnancy - Medical Xpress [Last Updated On: September 4th, 2017] [Originally Added On: September 4th, 2017]
- Society of Nuclear Medicine and Molecular Imaging (SNMMI) [Last Updated On: October 1st, 2017] [Originally Added On: October 1st, 2017]
- For Authors - Molecular Medicine [Last Updated On: October 1st, 2017] [Originally Added On: October 1st, 2017]
- Center for Applied Proteomics and Molecular Medicine [Last Updated On: October 15th, 2017] [Originally Added On: October 15th, 2017]
- Nuclear Medicine - Molecular Imaging - Nuclear Medicine ... [Last Updated On: August 3rd, 2018] [Originally Added On: August 3rd, 2018]
- Proteomics Conferences 2018 | Molecular Medicine Congress ... [Last Updated On: August 21st, 2018] [Originally Added On: August 21st, 2018]
- Section of Molecular Medicine | Wake Forest School of Medicine [Last Updated On: November 9th, 2018] [Originally Added On: November 9th, 2018]
- Faculty Research - Department of Molecular Medicine ... [Last Updated On: February 14th, 2019] [Originally Added On: February 14th, 2019]
- Goethe-Universitt Molecular Medicine (Master of Science) [Last Updated On: March 5th, 2019] [Originally Added On: March 5th, 2019]
- Biochemistry and Molecular Biology at Miller School of ... [Last Updated On: March 30th, 2019] [Originally Added On: March 30th, 2019]
- Molecular Medicine Research - Mayo Clinic Research [Last Updated On: April 27th, 2019] [Originally Added On: April 27th, 2019]
- Molecular Medicine (MolMed) | Duke School of Medicine [Last Updated On: April 27th, 2019] [Originally Added On: April 27th, 2019]
- Molecular Medicine | Molecular, Cellular and Developmental ... [Last Updated On: April 27th, 2019] [Originally Added On: April 27th, 2019]
- Home | EMBO Molecular Medicine [Last Updated On: May 5th, 2019] [Originally Added On: May 5th, 2019]
- Molecular Medicine (formerly Molecular & Cellular Biology) [Last Updated On: June 3rd, 2019] [Originally Added On: June 3rd, 2019]
- The world's first psilocybin research center is opening in Jamaica - Big Think [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Synthetic networks with tunable responsiveness, biodegradation, and molecular recognition for precision medicine applications - Science Advances [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- No place for racism: an open letter from University of Auckland staff - The Spinoff [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality - Beyond the Abstract - UroToday [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Tulane researcher is editor of journal issue honoring 40th anniversary of key cancer discovery - News from Tulane [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- New insights into heart's healing capacity - Baylor College of Medicine News [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Giving a Speed Boost to Nerve Regrowth - Technology Networks [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Exploring the stress-mood-appetite connection - Baylor College of Medicine News [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- What's in the cards for this year's Nobel Prizes? - STAT [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Treatment for Incurable Breast Cancer, Melanoma Improved by Adding Local Anesthetics - Newswise [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- DNA Nanomachines Are Opening Medicine to the World of Physics - Singularity Hub [Last Updated On: October 3rd, 2019] [Originally Added On: October 3rd, 2019]
- Institute of Human Virology Hosts 21st Annual International Meeting of Top Scientists on Ending the HIV/AIDS Epidemic in America and the Intersection... [Last Updated On: October 5th, 2019] [Originally Added On: October 5th, 2019]
- Digital Biopsies: Radiomics and Pathomics Are Important Stops on the Path to Precision Medicine - Cancer Therapy Advisor [Last Updated On: October 5th, 2019] [Originally Added On: October 5th, 2019]