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Kallyope Inc. Appoints Peter Hecht to Board of Directors – BioSpace

Posted: February 24, 2020 at 10:49 am

NEW YORK, Feb. 20, 2020 /PRNewswire/ -- Kallyope Inc., a leading biotechnology company focused on identifying and pursuing therapeutic opportunities involving the gut-brain axis, today announced that Peter Hecht, Ph.D., CEO of Cyclerion Therapeutics, has been appointed to the company's Board of Directors.

Prior to joining Cyclerion in 2019, Peter was co-founder and CEO of Ironwood Pharmaceuticals from 1998 to 2019. Under his leadership, Ironwood grew into a fully integrated research, development and commercial organization with more than 700 employees. During his tenure the company discovered, developed and commercialized LINZESS (linaclotide) globally for irritable bowel syndrome with constipation and chronic constipation. In 2019, Peter led the tax-free separation of Ironwood's non-gastrointestinal (GI) assets and R&D team into Cyclerion, enabling Ironwood to be a profitable GI therapeutics-focused leader. After completion of the spin-off, Hecht joined Cyclerion as its first CEO. He holds a Ph.D. in molecular biology from the University of California at Berkeley and was a post-doctoral research fellow at the Whitehead Institute.

"It is an exciting time to join Kallyope," said Hecht. "Their unique platform of integrated technologies has led to a new understanding of gut-brain circuits that has, in turn, resulted in the discovery of novel approaches to diseases of high unmet need in multiple therapeutic areas. I look forward to working with the team as the company begins to advance its portfolio of programs towards the clinic."

"We are delighted to welcome Peter to our Board of Directors at this pivotal time," said Nancy Thornberry, CEO of Kallyope. "As we progress our lead programs and expand our pipeline and novel platform, Peter's experience in building innovation-driven biotech startups into mature biopharmaceutical companies will be invaluable for us."

About Kallyope Inc.

Kallyope, headquartered at the Alexandria Centerfor Life Science in New York City, is a biotechnology company dedicated to unlocking the therapeutic potential of the gut-brain axis. The company's cross-disciplinary team integrates advanced technologies in sequencing, bioinformatics, neural imaging, cellular and molecular biology, and human genetics to provide an understanding of gut-brain biology that leads to transformational therapeutics to improve human health. The company's founders are Charles Zuker, Ph.D., Lasker Award winner Tom Maniatis, Ph.D., and Nobel laureate Richard Axel, M.D. For more information visitwww.kallyope.com.

Contact

Danielle Cantey(202) 337-0808dcantey@gpg.com

Morgan Warners(202) 337-0808mwarners@gpg.com

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New coronavirus, a map to tell the story of the infection – NJ MMA News

Posted: February 24, 2020 at 10:48 am

A map , built to tell the spread of the infection from new coronavirus in Italy . As the case count grows and the first two victims are registered, one 78 enne Paduan and a 75 enne lodigiana, Wired has decided to launch this tool to map the progress of the disease now arrived in Italy (NB: the map is not updated in real time, it takes time to verify the data).

As the virologist Giovanni Maga , director of the Cnr Institute of Molecular Genetics, comments in a press release, we are facing to an outbreak of virus Sars-Cov-2 infection. The numbers do not yet allow to speak of an epidemic. Of course, he adds, the picture could obviously change in the coming days, but our health system is in a state of maximum alert and capable of managing effectively also the possible appearance of other small outbreaks such as the current one .

To avoid excessive alarmism , continues Maga, is good to remember first that 19 cases [alla mattina del 22 febbraio, ndr] out of a population of 60 millions of inhabitants, however, make the risk of infection very low. Only in the areas currently affected by traffic is the risk higher and citizens must follow the indications of the health authorities. Outside of these, the situation remains as in the past weeks .

Here is what the information collected so far in the world tell : The infection, from epidemiological data available today on tens of thousands of cases, causes mild / moderate symptoms (a kind of flu) in the 80 90% of cases. In 10-15% pneumonia can develop, the course of which is however benign in the absolute majority. It is estimated that only 4% of patients require ICU admission. The risk of serious complications increases with age, and people over 65 years and / or with pre-existing or immunosuppressed diseases are obviously more at risk, as they would be for the flu .

Don't panic , in short. And precisely in an attempt to make an informative contribution to map the outbreaks of Covid 19 in Italy, Wired has created a dataset that everyone can update. Anyone with information to provide, can do so by filling out this form. Once verified by the editorial staff, the information will be entered and published.

The dataset feeds the map that opens this piece, but obviously anyone can use it to build their own. The goal, in fact, is to help provide information as accurate as possible about the spread of coronavirus in Italy.

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Well-known agricultural sector consultants and coverage makers are sharing their expertise within the Outlook Agriculture Conclave – Sahiwal Tv

Posted: February 24, 2020 at 10:48 am

Famous celebrities, coverage makers and consultants from the nation's agriculture sector are collaborating within the Outlook Agriculture Conclave to be held in New Delhi on Monday and professional periods to be held underneath it. In addition to the farmers within the Conclave, awards shall be given in varied classes to different organizations and establishments lively in agriculture. The winners who made particular contributions have been chosen by a jury of consultants in agriculture. The awards shall be offered by Union Agriculture Minister Narendra Singh Tomar on the concluding ceremony of the Conclave. Meghalaya Deputy Chief Minister Prestone Tiansoong, Agriculture Minister of Haryana, Jai Prakash Dalal will inaugurate the Conclave.

->Madhya Pradesh Agriculture Minister Sachin Yadav, Telangana Agriculture Minister S. Niranjan Reddy will deal with. The consultants and jury members becoming a member of the Conclave are as follows.

Haryana Agriculture Minister Jai Prakash Dalal

Haryana Agriculture Minister Jai Prakash Dalal would be the particular visitor. Brokers are very lively in fixing the present issues of farmers and enhancing their financial situation. He made nice efforts to implement the suggestions of the Swaminathan Commission.

Madhya Pradesh Agriculture Minister Sachin Yadav

Madhya Pradesh Agriculture Minister Sachin Yadav is working for the betterment of farmers. He is working to supply reduction to the farmers dealing with many issues within the state and to take ahead on the financial progress.

Meghalaya Deputy Chief Minister Prestone Tiansong

Meghalaya Deputy Chief Minister Meghalaya Prestone Tiansoong would be the particular visitor. 80 % of the inhabitants in Meghalaya depends on the agricultural sector. Due to this, agriculture sector is essential within the financial improvement of the state. The position of chief Tiansoong as deputy chief minister is essential.

Harish Chavan

Harish Chavan Mahindra & Mahindra Ltd. Okay. Swaraj is the Chief Executive Officer of the Division. He has 28 years of expertise in varied fields together with manufacturing, administration, technique planning, abroad business in India and overseas. Prior to taking cost of the Swaraj division, he held varied different vital positions within the Mahindra Group.

Vasudha Mishra

Vasudha Mishra, a 1987 batch IAS officer of Telangana cadre, is Special Secretary within the Ministry of Agriculture and Farmers Welfare. Prior to this she was Additional Secretary within the Department of Administrative Reforms and Public Grievances. She additionally held the place of Managing Director of National Cooperative Development Corporation. Prior to that, she has additionally dealt with a number of departments in Andhra Pradesh.

Dr. Trilochan Mohapatra

Dr. Trilochan Mohapatra is the Director General of the Indian Council of Agricultural Research (ICAR). Dr. Mahapatra, identified for his particular contribution within the area of molecular genetics and genomics, was awarded the National Biosciences Award by the federal government, one of many highest awards of Indian scientists for his contribution within the area of biosciences.

Vijay Sardana

Vijay Sardana, convener of the Food Security and Sustainable Agriculture Foundation, is the Vice President and Head of Food Security and Agribusiness, Policy and Program at UPL Group. They are related in several roles in lots of organizations of the nation. Sardana has additionally been concerned within the actions of the World Economic Forum, World Business Council for Sustainable Development, Initiative for Global Development and International Food Policy Research Institute.

Rajeev Rallan

Rajeev Rallan is the top of gross sales and advertising and marketing of Mahindra & Mahindra's Swaraj division. Rallan has been instrumental in popularizing Swaraj tractors and connecting farmers. He has taken initiative to attach farmers by taking initiative like cellular app to beat the issues of the day.

Sanjay gakhar

BTech Gakhar is the Vice President of MCX in Agriculture Engineering. He focuses on fields resembling commodity futures, provide chains and buying and selling. Prior to becoming a member of MCX in August 2005, he labored in establishments resembling Nafed and Britannia.

Sanjay Chhabra

Mr. Sanjay Chhabra is the President and Business Head of Shriram Farm Solutions of DCM Shriram. He has 27 years of in depth expertise within the area of Agri Input and Rural Market. Chhabra was instrumental within the improvement of greenery by DCS Shriram, the primary rural retail initiative within the nation.

Dan elf

Counselor Dan Elf of the International Development Cooperation, Science and Agriculture on the Israeli Embassy has held managerial positions within the agricultural sector. Dan Elph, who focuses on agriculture, has intensive expertise in gardening and crops administration. He obtained an MBA diploma after learning agriculture in Hebrew University from Hebrew University.

Anoop Vikal

Anoop Vikal is the Chief Financial Officer of Naira Energy. When he joined Naira Energy, the corporate was going via a transition. He performed a key position in management, threat administration and planning. He additionally oversees authorized and CSR actions within the firm. He has held senior positions at Snapdeal and Bharti Airtel.

Vineet Durani

Vineet Durani is the director of Microsoft and is accountable for buyer and partnership engagements. He has 24 years of expertise within the area of business administration. Durani has efficiently held a number of different tasks at Microsoft. Prior to Microsoft, he additionally served at Samsung and Modi Enterprises.

Sanjay agarwal

Sanjay Aggarwal, Secretary, Union Ministry of Agriculture and Farmers Welfare is a 1984 batch UP cadre IAS. He earned BTech and MTech levels from IIT Kanpur. Sanjay Agarwal, who held a number of posts within the Government of Uttar Pradesh, was additionally the Principal Secretary of the Department of Electricity. He additionally grew to become the Additional Chief Secretary of the state. Being on the post of Secretary within the Ministry of Agriculture, he has an vital position in figuring out the insurance policies of this sector. The most important accountability of doubling the revenue of farmers and implementing vital schemes of Modi authorities like Kisan Samman Nidhi is his personal ministry.

Dr. T. Haque

Dr. T. Haque has been the Chairman of the Commission for Agricultural Costs and Prices CACP and the top of Land Policy Cell of NITI Aayog. Eminent agricultural economist Dr. Haque is an professional within the area of agricultural improvement and insurance policies. He has been a senior marketing consultant in a number of organizations together with International Labor Organization, Food and Agriculture Organization and World Bank. Apart from the central authorities, he additionally served on a number of professional committees of the governments of Punjab and Andhra Pradesh. Dr. Haque has written a couple of dozen books and greater than 100 analysis papers. The most important emphasis of his books and articles was on matters like rural improvement, total coverage formulation for growing international locations, land reforms, agrarian reforms.

Sandeep Nayak

Sandeep Nayak, Managing Director of National Cooperative Development Corporation-NCDC has a variety of expertise within the cooperative sector. He has seen intently the position of cooperative sector in agriculture and upliftment of farmers. National Cooperative Development Corporation is doing important work on this space. Shri Nayak, an IAS from Jammu and Kashmir batch, has held a number of different posts apart from principal secretary of the agriculture division in Jammu and Kashmir. An International Cooperative Trade Fair was organized underneath his supervision.

Saurabh Kumar

Mr. Saurabh Kumar is the Chief Executive Officer of ICICI Foundation. He contributed considerably to the event of ICICI Digital Village. This expanded the market in rural areas and benefited the villages.

Dr. DN Nobleman

Dr. DN Thakur Sahkar is the nationwide vp of Bharti. Prior to this, Dr. Thakur served within the Ministry of Agriculture and Cooperation for a few years and gained intensive expertise within the area of cooperatives. He has additionally been the deputy MD of the National Cooperative Development Corporation (NCDC).

Vm Lion

Shri VM Singh is a outstanding farmer chief. Former MLA Mr. Singh can also be the National Convener of the All India Kisan Sangharsh Coordination Committee. They have been elevating the difficulty of entitlement of farmers from varied boards.

Dr. Ron Malka

Dr. Ron Malka is the Israeli Ambassador to India. After serving in economics and business administration, he served within the Israeli military. He then held senior positions within the Financial Advisory Unit of the IDF Intelligence Corporation and Chief of Staff. Having a eager understanding of financial and monetary issues, Dr. Malka can also be related to financial and monetary organizations in Israel and has instructing expertise.

R .s. Sodhi

RS Sodhi, managing director of Gujarat Cooperative Milk Marketing Federation Limited (Amul), has a big presence within the jury. Sodhi has performed an vital position in giving new route to the White Revolution. Such a mannequin of Amul developed in Gujarat that the milk farming business obtained a brand new route by adopting it everywhere in the nation. Sodhi focuses on market analysis, meals processing, FMCG and business improvement.

Dr . A.okay. Lion

Dr. A.Okay. Singh is the deputy director normal of the Indian Council of Agricultural Research-ICAR and is in control of the agricultural extension sector. Their presence within the jury is vital as a result of theyve been related to agricultural analysis for a very long time. Due to the vital position of agricultural analysis in doubling the revenue of farmers, their expertise and contribution is essential.

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Penn announces seven 2020 Thouron Award winners – Penn: Office of University Communications

Posted: February 24, 2020 at 10:46 am

Four University of Pennsylvania seniors and three recent alumni have won a Thouron Award to pursue graduate studies in the United Kingdom. Each scholarship winner receives tuition for as long as two years, as well as travel and living stipends, to earn a graduate degree there.

Established in 1960 and supported with gifts by the late John Thouron and his wife, Esther du Pont Thouron, the Thouron Award is a graduate exchange program between Penn and U.K. universities that aims to improve understanding and relations between the two countries.

Penns seven 2020 Thouron Scholars are:

Daniel Brennan

Senior Daniel Brennan, of Miami, is a varsity oarsmen for Penns lightweight crew team majoring in history and political science, with concentrations in military history and political theory in the School of Arts and Sciences. As a United States Marine and past moderator of the Universitys Philomathean Society, he is an advocate for greater civil-military awareness. Brennan works on national security policy as a Student Fellow at the Perry World House and is writing his honors thesis on the development of counterinsurgency strategy during the Cuban War of Independence. He is a Benjamin Franklin Scholar and has worked on anti-hunger issues both as a Fox Leadership Fellow with the Catholic Archdiocese of Philadelphia and by organizing his crew teams meal-packing events. In the U.K., he plans to pursue a masters degree in military history.

Braden Cordivari

Braden Cordivari, of Elverson, Pennsylvania, is a 2018 graduate of the College of Arts and Sciences. He received his bachelors degree in classical studies and anthropology with a minor in archaeological science. Since 2015, he has continued to work at Penns excavations at the ancient Iron Age city of Gordion in Turkey. He spent the 2018-19 academic year as a John Williams White Fellow at the American School of Classical Studies at Athens completing a program of intensive study of Greek archaeology and history. His research interests include human/environment relationships in the past and the study of craft production through science-based methods. Cordivari plans to pursue a masters degree in archaeological science at the University of Cambridge.

Gregory Forkin

Gregory Forkin, of Philadelphia, is a 2019 graduate with a bachelors degree in mathematics, physics, and biology and a minor in chemistry. He was a University Scholar and a member of Phi Beta Kappa. Currently, he is conducting research in neuroscience under Professor Vijay Balasubramanian and is a teaching assistant in the Math Department in the School of Arts and Sciences. Forkin plans to pursue a masters degree in pure mathematics at the University of Cambridge.

Natasha Menon

Senior Natasha Menon, of Scottsdale, Arizona, is pursuing a major in philosophy, politics, and economics with a concentration in distributive justice and a minor in legal studies and history in the School of Arts and Sciences. Menon serves as president of the Undergraduate Assembly, through which she works to elevate the voices of marginalized communities on campus to effect change. She is also a Civic Scholar, and has volunteered at Moder Patshala, a Bangladeshi immigrant services center in Philadelphia, for three years. Menon plans to pursue a masters degree in international migration and public policy at the London School of Economics. Upon returning to the U.S., she hopes to pursue a law degree and engage in public service in Arizona.

Robert Subtirelu

Senior Robert Subtirelu, from Ronkonkoma, New York, is majoring in the biological basis of behavior and minoring in chemistry in the School of Arts and Sciences. A recipient of the 2019 Clinical and Translational Research Award, he has conducted research with the Perelman School of Medicines Department of Neurosurgery to investigate post-traumatic epilepsy. He works as a teaching assistant, volunteers with Wissahickon Hospice, and remains an active member of Penns Medical Emergency Response Team. He also founded and coordinated the activities of a not-for-profit organization that has established educational and nutritional programs internationally. Subtirelu plans to pursue a masters degree in clinical and therapeutic neuroscience at the University of Oxford.

Zachary Whitlock

Senior Zachary Whitlock, of Washington, D.C., is in the Vagelos Integrated Program in Energy Researchjoint-degree program, majoring in materials science and engineering in the School of Engineering and Applied Science and in earth science in the School of Arts and Sciences. Whitlock has workedon biomimetic functional materialswith Penn Engineerings Shu Yang Laboratory and internationally at the French Alternative Energies and Atomic Energy Commission. More recently, he worked at the intersection of industrial materials and environmental impact on the Kleinman Center for Energy Policy-funded project Fossil Fuels, the Building Industry, and Human Health. He is a 2020 Kleinman Undergraduate Fellow and Supported Student at the Water Center at Penn. He is planning to pursue a masters degree in environmental systems engineering at University College London and ultimately hopes to contribute to the sustainability and impact mitigation of projects reliant on ecosystem services.

Maia Yoshida

Maia Yoshida, of Madison, New Jersey, received her bachelors degree in 2018 in molecular and cell biology with a minor in fine arts. She is now a researcher in a bioengineering lab, engineering immune cells to better fight cancers. While at Penn, she researched the molecular mechanisms involved in neurodegenerative diseases and was a teaching assistant for a fine arts course on biological design. She also taught elementary school science at the Penn Alexander School in West Philadelphia. As the president of Global Brigades at Penn, she led fundraising efforts for sustainable development projects in Honduras. Yoshida plans to pursue a masters degree in STEM Education at Kings College London.

TheCenter for Undergraduate Research and Fellowshipsserves as Penns primary information hub and support office for students and alumni applying for major grants and fellowships, including the Thouron Award.

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What is reason for deaths of nine children in Udhampur? – TheDispatch

Posted: February 23, 2020 at 7:46 am

Jammu: The initial probe has found that poisonous compound in a cough syrup cause the death of nine children in district Udhampur in the month of January.

The cough syrup is manufactured by Digital Vision- Himachal Pradesh-based pharmaceutical company and other states have also been asked to stop its sale and distribution.

Prima facie, presence of Diethylene Glycol, a poisonous compound, in Coldbest-PC syrup caused the death of children from Udhampur district, PGIMER, Chandigarh, officials have told us, said Surinder Mohan, the assistant drugs controller, Drug and Food Control Organisation, J&K.

Mohan also said that the samples of the syrup, manufactured by the Himachal Pradesh-based pharmaceutical company, have been sent to the Indian Institute of Integrative Medicine, Jammu, and Regional Drugs Testing Laboratory, Chandigarh, for further tests.

Konic Goyal, the managing director of Digital Vision, told the Indian Express that they would not like to say anything on the issue at the moment. The general manager (marketing), Sushil Yadav said, Production of the medicine has been stopped and we have provided all information to the state drugs control authorities.

The Jammu and Kashmir Drug Controller Latika Khajuria said that the final report from the Regional Drugs Testing Lab was awaited even though the PGIMER report had located the presence of Diethylene Glycol in the syrup. Once we receive that report, we will find what actually led to the deaths. The syrup has already been recalled, she said.

In January, almost ten children died of a mysterious disease while six others were taken ill in J&Ks Udhampur district following which the Centre deployed a team of medical experts to probe the cause of deaths.

The Director Health Services (DHS), Jammu, Renu Sharma said that the deaths took place between December-end and January 17 in Udhampurs Ramnagar block. The patients were hospitalised with acute renal failure. The common factor found in all the deaths was that they took Coldbest-PC, she said.

Sharma also said that of the 17 children who had been affected, nine had died.

The presence of an impurity, diethylene glycol, was detected in the cough syrup and found to be present in the solvent propylene glycol (PG), used in the syrup. Its origin has been traced to Chennai-based Manali Petrochemicals. The solvent was sold to two Delhi-based traders, who then sold it to a trader in Ambala, from where it found its way to the Kala Amb-based Digital Vision pharmaceutical unit.

The firms manufacturing licence has since been withdrawn.

Close to 5,500 units of the drug are being recalled from eight states and the Himachal Pradesh health safety and regulation authorities have suspended all production at Digital Visions unit at Kala Amb in Sirmaur district, where Coldbest-PC Syrup was manufactured.

In a letter to the Himachal Pradesh drugs controller, Jammus drugs controller said that after a team of doctors from PGIMER, Chandigarh visited Ramnagar last month to probe the probable cause of the deaths, Diethylene Glycol was found in below pharmaceutical preparation. The letter has also been copied to all state and UT Drug Controllers across India.

The team of doctors from PGIMER comprised of experts from the departments of Paediatrics, Community Medicine and Virology. A senior PGIMER doctor, who was a part of the visiting team said that samples of the syrup contained Diethylene Glycol.

The batch of the syrup believed to be containing the poisonous compound was produced in September 2019. As a precautionary measure, the entire stock is being recalled and production at the factory was stopped on February 17. We are also trying to reach users who bought it, a Himachal official said.

The Himachal Pradesh drugs controller said that apart from those in Udhampur, no other case related to the cough syrups effects had been reported so far.

Haryana DGHS Suraj Bhan Kamboj said the state had banned the cough syrup and the departments teams were conducting raids at chemist shops to check availability.

TheDispatch | An Indian media startup, looking at the country and the world from Jammu and Kashmir

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Nine dead, five injured in Kathua mishap – The Kashmir Monitor

Posted: February 23, 2020 at 7:46 am

New Delhi, Feb 22: In a bid to address the concerns of the local populace after the revoking of Jammu and Kashmirs special status last year, Union Minister Jitendra Singh on Saturday assured the people of the Union Territory that the domicile law is coming very soon which would be followed by the Land Act.He also announced that more than the promised jobs will be provided to the youth after the notification of the rules is worked out.The domicile act is coming very soon, which will be immediately followed by the Land Act, the minister of state in the Prime Ministers Office said.Many parties have been demanding enactment of a domicile law for Jammu and Kashmir to protect the interests of landowners and the unemployed youth after the erstwhile state lost its special status following nullification of Article 370 by the Centre.Singh was addressing a function after signing of a major scientific collaboration agreement between CSIR-Indian Institute of Integrative Medicine, Jammu, and IndusScan, a Canadian pharmaceutical company, here.Describing the signing of the MoU as a historic moment, the minister said Jammu and Kashmirs journey to become a part of Indias five trillion global economy has started from the four walls of IIIM.Prime Minister Narendra Modi is saying again and again that we would have the same kind of focus on Jammu and Kashmir and Ladakh as we did for North-East which saw major transformation over the last five years. Those who have doubts about it would see all this happening in a short while of time, he said.The minister said this is possible because the earlier embargoes have been removed and the Union Territory is directly reporting to the Centre.Many of the politicians have become unemployedheard yesterday one of them raising the issue of jobs to the local youth. I want to tell that more than the promised jobs will be advertised but as per the rules and in an impartial manner. We are waiting for a notification of the rules to come out, he said.Alleging brazen disregard for the concerns of the educated unemployed and underemployed youth by the incumbent government, National Panthers Party Chairman and former minister Harsh Dev Singh had said not a single post, out of the promised 50,000 jobs, had been advertised for filling up in the new UT after the abrogation of Article 370 provisions.Everything will be done. It will not be like when your government was in power and ruined the future of the youths by backdoor appointments and corrupt practices. The youth who were provided jobs have turned 35 years but are still waiting for their regularisation, the Union minister said.He said the jobs will be provided under rules which will be in the best interest of the youth and those who have been deprived of it.Asserting that India is going through one of the best phases under the leadership of Modi, he said a lot of development had taken place over the last five years and the country is looking forward to become a part of the global economy.On the one hand India is eyeing five trillion economy, dont you want that Jammu and Kashmir should also be part of that. It is possible only when our youth reaches such a stage to live up to the parameters which are followed globally and therefore, even if some of us have any doubts, confusion and skepticism or still unconvinced, ask themselves that dont you want your children to be part of five trillion economy.If you understand it, I think all the murmuring and whispering which is generated from thoughtless minds will vanish away, Singh said.The minister said Jammu and Kashmir is also under the process of a new industrial policy and a new scientific policy.The greatest disadvantage that has happened from Jammu and kashmir remaining in isolation because of Article 370 is that we become lazy and lethargic. We learnt to live on easy freebies, he said.

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POTUS India visit: Trump expected to talk Kashmir,says US Officials – The Kashmir Monitor

Posted: February 23, 2020 at 7:46 am

New Delhi, Feb 22: In a bid to address the concerns of the local populace after the revoking of Jammu and Kashmirs special status last year, Union Minister Jitendra Singh on Saturday assured the people of the Union Territory that the domicile law is coming very soon which would be followed by the Land Act.He also announced that more than the promised jobs will be provided to the youth after the notification of the rules is worked out.The domicile act is coming very soon, which will be immediately followed by the Land Act, the minister of state in the Prime Ministers Office said.Many parties have been demanding enactment of a domicile law for Jammu and Kashmir to protect the interests of landowners and the unemployed youth after the erstwhile state lost its special status following nullification of Article 370 by the Centre.Singh was addressing a function after signing of a major scientific collaboration agreement between CSIR-Indian Institute of Integrative Medicine, Jammu, and IndusScan, a Canadian pharmaceutical company, here.Describing the signing of the MoU as a historic moment, the minister said Jammu and Kashmirs journey to become a part of Indias five trillion global economy has started from the four walls of IIIM.Prime Minister Narendra Modi is saying again and again that we would have the same kind of focus on Jammu and Kashmir and Ladakh as we did for North-East which saw major transformation over the last five years. Those who have doubts about it would see all this happening in a short while of time, he said.The minister said this is possible because the earlier embargoes have been removed and the Union Territory is directly reporting to the Centre.Many of the politicians have become unemployedheard yesterday one of them raising the issue of jobs to the local youth. I want to tell that more than the promised jobs will be advertised but as per the rules and in an impartial manner. We are waiting for a notification of the rules to come out, he said.Alleging brazen disregard for the concerns of the educated unemployed and underemployed youth by the incumbent government, National Panthers Party Chairman and former minister Harsh Dev Singh had said not a single post, out of the promised 50,000 jobs, had been advertised for filling up in the new UT after the abrogation of Article 370 provisions.Everything will be done. It will not be like when your government was in power and ruined the future of the youths by backdoor appointments and corrupt practices. The youth who were provided jobs have turned 35 years but are still waiting for their regularisation, the Union minister said.He said the jobs will be provided under rules which will be in the best interest of the youth and those who have been deprived of it.Asserting that India is going through one of the best phases under the leadership of Modi, he said a lot of development had taken place over the last five years and the country is looking forward to become a part of the global economy.On the one hand India is eyeing five trillion economy, dont you want that Jammu and Kashmir should also be part of that. It is possible only when our youth reaches such a stage to live up to the parameters which are followed globally and therefore, even if some of us have any doubts, confusion and skepticism or still unconvinced, ask themselves that dont you want your children to be part of five trillion economy.If you understand it, I think all the murmuring and whispering which is generated from thoughtless minds will vanish away, Singh said.The minister said Jammu and Kashmir is also under the process of a new industrial policy and a new scientific policy.The greatest disadvantage that has happened from Jammu and kashmir remaining in isolation because of Article 370 is that we become lazy and lethargic. We learnt to live on easy freebies, he said.

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Man Accused Of Running Illegal Long Island Health Clinic – Daily Voice

Posted: February 23, 2020 at 7:45 am

A Long Island man is facing a host of charges for allegedly posing as a medical professional and running an illegal health clinic, where he treated patients.

Brian Michael Kaufman, 45, of Smithtown, allegedly ran Mens Health Solution of Smithtown on Middle Country Road, despite not having a medical license, Suffolk County DA Tim Sini announced.

He allegedly treated patients, including testosterone and steroid injections.

The investigation into Kaufmans practice determined that he allegedly has been operating the medical practice since at least August last year.

When he was arrested, Kaufman admitted to investigators that he was not licensed to practice any medical profession and had no training to provide medical services or provide testosterone replacement therapy, the DA said.

Mens Health Solution of Smithtown has since shuttered its doors.

"This individual put lives in danger and posed a clear threat to public health by masquerading as a medical practitioner," Sini said in a statement. "He did not have patients; he had victims. We are asking those victims to please contact the District Attorney's Office with any information they may have about Kaufman's alleged scam."

Kaufman has been charged with:

"This case is significant because it unearthed a convicted felon playing doctor who jeopardized his 'patients' lives," DEA agent Ray Donovan said. "In order to safeguard our communities, law enforcement has to act fast when they see someone threatening public health and safety.

"In this case, Brian Kaufman's alleged testosterone trafficking ring put people in harm's way while committing several crimes."

If convicted, Kaufman faces up to seven years in prison on the top count. He was arraigned this week and released with a GPS monitoring device. He will also be subjected to drug testing and is under travel restrictions.

Anyone who has received medical services from Kaufman or at Mens Health of Smithtown has been asked to contact the Suffolk County District Attorneys Office by calling (631) 853-8087.

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Man Accused Of Running Illegal Long Island Health Clinic - Daily Voice

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In the Wrong Body – Teen Girl to Teen Boy – Deutsche Welle

Posted: February 23, 2020 at 7:45 am

What do parents do when they learn their daughter suddenly wants to be a boy? When Rene entered puberty, she began to change, her hair becoming shorter and shorter, her dress more androgynous. Parents Birgid and Michael initially thought she was just trying things out, until one day Rene outed herself as transgender during a family walk. Her parents were relieved, but also very worried about what it could mean for the future. They found an experienced youth psychotherapist to accompany Rene closely for the next few years as she became Ren. After a year of psychotherapy, the therapist recommended hormone replacement therapy. The testosterone quickly changed Rens body: his voice broke, his hair became thicker and his whole posture more male. For him it was a liberation, but Birgid has to struggle with the loss of a daughter for good. How will Ren develop now? What other changes will hormone therapy bring, and what will it do to him? Its the start of a long journey for Ren and his parents.

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In the Wrong Body - Teen Girl to Teen Boy - Deutsche Welle

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FDA Authorizes Marketing of the First Genetic Test to Aid in the Diagnosis of Fragile X Syndrome – FDA.gov

Posted: February 23, 2020 at 7:44 am

For Immediate Release: February 21, 2020

The U.S. Food and Drug Administration today authorized marketing of the first test to detect a genetic condition known as Fragile X Syndrome (FXS), the most common known cause of inherited developmental delay and intellectual disability. The test is intended as an aid in diagnosing FXS and is to be used along with the evaluation of a patients family history and clinical signs and symptoms of FXS. Additionally, this test is intended for use in adults who may be carriers of genetic alterations in the gene associated with FXS, called the FMR1 gene.

This novel diagnostic provides doctors and their patients the first FDA authorized genetic test to aid in diagnosing Fragile X Syndrome, as well as helping parents know their risk of having a child with Fragile X Syndrome, said Wendy Rubinstein, M.D., Ph.D., director of personalized medicine in the Office of In Vitro Diagnostics and Radiological Health at the FDAs Center for Devices and Radiological Health. Early diagnosis is key to helping children affected with Fragile X Syndrome through early intervention.

According to the Centers for Disease Control and Prevention, approximately 1 in 4,000 males and 1 in 8,000 females in the U.S. have FXS, which is a genetic disorder caused by changes in the FMR1 gene located on the X chromosome. A segment of the DNA in the gene, known as a CGG trinucleotide repeat, is repeated in excess on the X chromosome in individuals with this disorder. While some repetition of the CGG repeat is normal, a high number of repeats may indicate potential health risks. The AmplideX Fragile X Dx and Carrier Screen Kit uses blood specimens from patients to measure the number of repeats of the CGG segment in the FMR1 gene. The test can determine whether a patient has a number of CGG repeats that is considered either normal, intermediate, premutation or full mutation.

Individuals with a full mutation typically have FXS, which is associated with developmental delays, learning disabilities, social and behavioral issues, intellectual disabilities and autism spectrum disorder. Women with a premutation have an increased risk of having a child with FXS as compared to women without a premutation. The number of women who have the Fragile X premutation is believed to be approximately 1 in 150 women. Men with a premutation will pass the premutation to their daughters only. Individuals with normal or intermediate levels of repeated CGG segments are currently thought to be asymptomatic for FXS or other fragile X-associated disorders.

In addition to aiding in the diagnosis of FXS and for carrier testing, this test can be used as an aid in the diagnosis of fragile X-associated disorders, including fragile X-associated tremor/ataxia syndrome, which is a movement and cognitive disorder that typically occurs in adults over age 50, and fragile X-associated primary ovarian insufficiency, a condition that is characterized by reduced function of the ovaries. The AmplideX Fragile X Dx and Carrier Screen Kit is not intended for use in fetal diagnostic testing, the screening of eggs obtained for in-vitro fertilization prior to implantation, or standalone diagnoses of FXS.

The FDA reviewed data for this test through the de novo classification process, a regulatory pathway for low- to moderate-risk devices of a new type. During this process, the FDA evaluated data from specimens collected at three clinical sites to assess the accuracy of the test. The data demonstrated that the diagnostic accuracy of the test is greater than 95%.

Along with this authorization, the FDA is establishing criteria, called special controls, that test developers must meet for tests of this type, including requirements relating to labeling and performance testing. These special controls, when met along with general controls, provide a reasonable assurance of safety and effectiveness for tests of this type. This action also creates a new regulatory classification, which means that subsequent devices of the same type with the same intended use may go through the FDAs 510(k) pathway, whereby devices can obtain clearance by demonstrating substantial equivalence to a predicate device.

The FDA granted marketing authorization of the AmplideX Fragile X Dx and Carrier Screen Kit to Asuragen Inc.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nations food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

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FDA Authorizes Marketing of the First Genetic Test to Aid in the Diagnosis of Fragile X Syndrome - FDA.gov

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