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Genetic Engineering | Talking Glossary of Genetic Terms …

Posted: September 7, 2019 at 4:32 pm

Genetic engineering is a term that was first introduced into our language in the 1970s to describe the emerging field of recombinant DNA technology and some of the things that were going on. As most people who read textbooks and things know, recombinant DNA technology started with pretty simple things--cloning very small pieces of DNA and growing them in bacteria--and has evolved to an enormous field where whole genomes can be cloned and moved from cell to cell, to cell using variations of techniques that all would come under genetic engineering as a very broad definition. To me, genetic engineering, broadly defined, means that you are taking pieces of DNA and combining them with other pieces of DNA. [This] doesn't really happen in nature, but is something that you engineer in your own laboratory and test tubes. And then taking what you have engineered and propagating that in any number of different organisms that range from bacterial cells to yeast cells, to plants and animals. So while there isn't a precise definition of genetic engineering, I think it more defines an entire field of recombinant DNA technology, genomics, and genetics in the 2000s.

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Goodie Mob – Cell Therapy (Official Video)

Posted: September 7, 2019 at 4:32 pm

Goodie Mob's official music video for 'Cell Therapy'. Click to listen to Goodie Mob on Spotify: http://smarturl.it/GMobSpotify?IQid=G...

As featured on Dirty South Classics. Click to buy the track or album via iTunes: http://smarturl.it/GMobDSCiTunes?IQid...Google Play: http://smarturl.it/GMobCTplay?IQid=GM...Amazon: http://smarturl.it/GMobDSCAmz?IQid=GM...

More from Goodie MobThey Don't Dance No Mo': https://youtu.be/vDmGnGueik8Black Ice (Sky High): https://youtu.be/F9ULbmCvmxYSoul Food: https://youtu.be/nKO43xG66OI

More great Classic Hip Hop videos here: http://smarturl.it/ClassicHipHop?IQid...

Follow Goodie MobWebsite: http://goodiemobmusic.com/Facebook: https://www.facebook.com/GoodieMobMusicTwitter: https://twitter.com/GoodieMobMusicInstagram: https://instagram.com/goodiemob/

Subscribe to Goodie Mob on YouTube: http://smarturl.it/GMobSub?IQid=GMobCT

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Lyrics:

When the scene unfoldsYoung girls thirteen years oldExpose themselves to any Tom, Dick, and HankGot mo' stretch marks than these hoesHollin they got rankSee Sega ain't in this new world order Dem experimenting in Atlanta, GeorgiaUnited Nations, overseasthey trained assassins to do search and seizeAin't knocking or askingDem coming for niggas like mePo' white trash, like theyTricks like her back in slaveryConcentration camps lace with gas pipes linesInferno's outdoors like they had backWhen Adolf Hitler was living in 1945Listen to me now, believe meLater on in the future look it upWhere they say it? Aint no more ConstitutionIn the event of a race warPlaces like operation heartbreak hotelMoments tear until air tight vents seat off despairDem say expect no mercyFoot you should be my least worries got to deal withWhere my W-2's, 1099'sUnmarked black helicopters swoop downAnd try to put missiles in mines

Who's that peeking in my window POW nobody now

#GoodieMob #CellTherapy #Vevo

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Goodie Mob - Cell Therapy (Official Video)

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Stem Cell Baton Rouge Louisiana 70833

Posted: September 7, 2019 at 4:28 pm

Stem cell therapy has actually ended up being a popular dispute in the global medical scene. This extremely questionable therapy has received combined viewpoints from numerous stakeholders in the healthcare market and has also brought in the interest of political leaders, religious leaders and the general population at large. Stem cell treatment is considered a revolutionary treatment for people suffering from a large range of degenerative conditions. Some common questions concerning this therapy are addressed listed below.

Are you a stem cell therapy provider in Baton Rouge LA 70833? Contact us for more information about joining our website.

Stem cells can be referred to as blank state or non-specialized cells that have the ability to become customized cells in the body such as bone, muscle, nerve or organ cells. This suggests that these unique cells can be used to restore or establish a wide variety of broken cells and tissues in the body. Stem cell treatment is for that reason a treatment that focuses on achieving tissue regeneration and can be utilized to treat health conditions and illnesses such as osteoarthritis, degenerative disc disease, spinal cord injury, muscular degeneration, motor nerve cell illness, ALS, Parkinsons, heart problem and much more.

Being a treatment that is still under research, stem cell therapy has not been totally accepted as a viable treatment alternative for the above discussed health conditions and diseases. A great deal of studio is currently being carried out by scientists and medical experts in numerous parts of the world to make this treatment sensible and efficient. There are nevertheless numerous constraints enforced by governments on studio including embryonic stem cells.

Currently, there havent been many case studies performed for this form of treatment. Nevertheless, with the few case studies that have been performed, among the significant issues that has actually been raised is the increase in a clients threat of establishing cancer. Cancer is triggered by the quick reproduction of cells that tend not to pass away so easily. Stem cells have actually been connected with comparable growth aspects that might result in formation of tumors and other malignant cells in clients.

Contact us for more information about stem cell therapy in Baton Rouge LA 70833

Stem cells can be drawn out from a young embryo after conception. These stem cells are commonly referred to as embryonic stem cells. After the stem cells are extracted from the embryo, the embryo is terminated. This is basically one of the significant causes of debate in the field of stem cell research study. Lots of people suggest that termination of an embryo is dishonest and undesirable.

Stem cells can still be gotten through other methods as they can be discovered in the blood, bone marrow and umbilical cords of adult humans. Typical body cells can likewise be reverse-engineered to become stem cells that have actually limited capabilities.

New studio has nevertheless revealed promise as scientists aim at developing stem cells that do not form into tumors in later treatment phases. These stem cells can for that reason successfully transform into other kinds of specialized cells. This therapy is for that reason worth investigating into as numerous clients can gain from this innovative treatment.

Need a stem cell provider close to Baton Rouge LA 70833

4.96

Main address:Baton Rouge, Louisiana, 70833

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Stem Cell Baton Rouge Louisiana 70833

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Biocellular Regenerative Medicine – About Us

Posted: September 7, 2019 at 4:27 pm

We are a very experienced professional medicalpractice, and leaders in the field of adult stem cells in Cellular (IV) & Biocellular Regenerative Therapies for a variety of issues from systemic disorder to arthritis, low back pain,orthopedic problems, chronic pain or wounds, bone and joint damage or degeneration. PLUS , we offer full aesthetic-cosmetic surgery(using your own adult tissues) to promote skin and body health, as well as a rewarding appearance for our patients. Our entire team is committed to meeting those needs. As a result, a high percentage of ourpractice is from direct person-person referral,internet,and by word of mouth. We are proud of our reputation and experience. I suggest that you review the physician credential selection on the right side of page to better understand ourexperienceas leaders in this area of Medicine &Surgeryincluding medical publications, Board certification, and experience.We offer appointments in our Western Montana offices.Use the contact form to send usspecific questions or information about your problems, but be certain to include your email or phone contact. If not included, we will be unable to respond as we do not capture visitor information without that contact form completion. We are here tohelpprovide you detailed information of how use of cellular and biologic therapies can help you heal yourself and return tomore normal daily work and recreational activities.

CELLULAR THERAPY now rapidly evolving, helping patients with systemic disease that are poorly or not responsive to current medications or invasive surgeries. This is completed on an outpatient, same day time frame with no alterations of the adult stem/stromal cells within your own body. Ask about whether you are a candidate, or have troubling systemic disease or degenerative changes.

Learn how you can help heal yourself.......Often without use of prescription drugs or surgery!

We would welcome the opportunity to earn your trust and deliver you the highest service we are able.

Northwestern United States Location:

Robert W. Alexander, MD, FICS

715 Main Street

Suite B

Stevensville, MT 59870 (Conveniently located South of Missoula, MT

(406) 777-4477 FAX (406) 866-766-5458

Hours:

Mon - Fri: 9AM - 5PMBy Appointment Only

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Biocellular Regenerative Medicine - About Us

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Stem Cell Treatment Rhode Island – Boston Stem Cell Center

Posted: September 7, 2019 at 4:26 pm

Stem cell treatment can treat a wide array of medical conditions. Learn more about what we can treat by reading the information below:

Constant knee problems can make it challenging to move from one part of your house to another. Some doctors may recommend knee surgery, knee joint replacement or a knee athroplasty to treat the pain in your knees.

However, choosing to undergo surgery may entail a long recovery time. After your operation, you may need to stay in the hospital for a few days. Moreover, you might not be allowed to drive or carry heavy things for the next 3 months.

Stem cell treatment is one method to help heal our body naturally. Found throughout our body, stem cells can developed into different cells, such as cartilage cells that can help joints. We use your stem cells for this procedure that we extract from the bone marrow in your hip bone. After that, we inject the cells together with platelet-rich plasma back into your knee.

Injuries, arthritis, and bursitis are some causes of hip pain. Without proper treatment, this can impair your movement and even cause difficulty in sleeping.

Hip surgery or hip joint replacement are common procedures for hip pain, mobility problems, and more. However, they may not have lasting effects. For example, you may need another hip replacement surgery after about 10 to 15 years.

At the Boston Stem Cell Center, we offer stem cell treatments as an alternative for patients experiencing hip pain. We use your own stem cells to help heal hip joints and help other local repair processes. Our stem cell treatment can help reduce inflammation, provide pain relief, and improve function.

Osteoarthritis and rotator cuff tendon tear are some reasons why you may experience shoulder pain. Sometimes, nonsurgical treatment such as medications may not be enough to alleviate the pain. Your doctor may recommend surgery if you are experiencing chronic pain.

If you are looking for alternatives to surgery, choosestem cell treatment. Stem cells can help with the natural healing process of the body. They can also keep your painful shoulder condition from progressing and suppress inflammation that can make injuries more painful.

Injuries and medical conditions can cause various ankle and foot pains. For example, you can get injured while running in an uneven plane in Providence, R.I. Severe foot pain can hamper your mobility and interfere with your daily activities.

Sometimes, nonsurgical treatments are not enough to treat severe ankle or foot pain. A doctor may subsequently recommend surgery as treatment. However, surgical procedures may cause complications, such as blood clots, infections, or muscle loss. Stem cell treatment is a viable alternative if you want to avoid surgery.

Elbow pain can limit your movement. Additionally, living in pain may require you to make drastic lifestyle changes. Surgeries can cure various elbow pain issues. However, you need to go through physical rehabilitation for up to 6 months as part of the recovery process.

Stem cell treatment is a reliable alternative in treating elbow pain naturally. We aspirate stem cells from bone marrow. After that, we can inject stem cells and platelet-rich plasma into the affected area. Normally, one stem cell treatment can address various elbow problems.

Medications and drug injections are some common ways of treating spine or back pain. Surgery is another viable procedure as well. However, if you are not comfortable with undergoing surgery, then consider some alternatives. Stem cell treatment can help heal affected joints, generate new tissue, and prevent further inflammation.

Strains, tears, and contusions may cause various skeletal muscle injuries. Nonsurgical procedures can treat muscle pain. Doctors may also recommend surgery in case nonsurgical procedures dont work.

In case you dont want to get surgery, there are other options available. Stem cell treatment can help cure tendon or muscle pain. This treatment can also promote muscle repair and speed up your recovery.

Medical conditions, injuries, or accidents may cause pain in your hands or wrists. Sometimes, doctors may recommend surgery to treat various conditions. If you are not comfortable with surgery, then you can opt for stem cell treatment. Improve mobility, speed up recovery, and minimize pain with the help of stem cell treatment.

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Stem Cell Treatment Rhode Island - Boston Stem Cell Center

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Rhode Island Stem Cells | Stem Cell TV | Page 3

Posted: September 7, 2019 at 4:26 pm

Posted: September 27, 2014 at 8:55 am

As we age, many of us experience the formation of deep lines and wrinkles in the face and a loss of volume in facial features that can give us a hollowed or sunken appearance in a number of areas including the lips and jaw-line folds between the cheeks and lips.

These very common aesthetic issues can be significantly improved with fat and stem cell injections, available from our Providence, Rhode Island plastic surgeon. Read on for more details on this effective procedure, and please contact Dr. Patrick K. Sullivan to schedule a consultation.

Fat and adipose derived stem cells are harvested from one part of the body (usually through a tiny incision in the belly button) and are injected in areas of the face where fat has been lost over time. It can be used to fill in the deep lines between the nose and cheek (nasolabial folds), the corners of the mouth (where the mouth may have a down-turned or frowning appearance), and/or deep creases in the forehead. Fat and stem cells can be used to augment the cheeks, lips, jaw-line, chin and other areas of the face. Fat and stem cell injections can be particularity beneficial in areas where there has been facial deflation that comes with the passage of time and from a host of other reasons.

Fat and stem cell injections are done under intravenous sedation without general anesthesia on an outpatient basis. The areas may be swollen for several weeks after surgery and it will take a number of weeks to see the final outcome.

I cannot express how delighted I am with the results from my surgery. It has made such a wonderful impact in my life and gave me a new outlook that was long overdue. I commend Dr. Sullivan for performing such a superb job. He is the best. Not only am I impressed with Dr. Sullivan but I am especially pleased with his staff. You all have been so kind to me. It is a breath of fresh air to see happy and professional people in one place. I am forever grateful. I will never forget this pleasurable experience. Name omitted for patient privacy

Dr. Patrick K. Sullivan can give you effective facial rejuvenation with results that bring out your natural beauty. With fat and stem cell injections, you can attain significant aesthetic enhancement in a variety of facial areas with results that are known to be long-lasting, as Dr. Patrick Sullivan has proven with his clinical research. He has followed hundreds of his patients over more than a ten year period and has proven that the transfer of fat maintains results for very long periods of time. Additionally, he has lectured to many of his peers about the latest techniques and the many benefits of utilizing fat and stem cell injections. Please contact us if you would like to learn more about this cutting-edge procedure and to schedule your private consultation with Dr. Sullivan.

View post:Fat Injections Transfer Contouring Rhode Island RI

Posted: at 8:55 am

An Advanced Solution

Why Stem Cells?

Stem cells are tiny progenitor cells found in our body that can divide (through mitosis) and change (differentiate) into various cell types. All cells in our body are constantly dividing where new cells are formed, then cells age and die. It is a natural physiologic process of programmed cell death and is known as Apoptosis. Your stem cells are your bodys natural healing cells and can act as your repair system in your body by replenishing adult tissues. They are the source of all these cells that have died.

There are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocyst (early stage of embryo), and non-embryonic or adult stem cells. It is also referred to as mesenchymal stem cells MSCs and is found in various tissues. There are three accessible sources of autologous adult stem cells in humans:

Stem cells can also be taken from umbilical cord blood just after birth. Of all stem cell types, autologous harvesting (cells are obtained from one's own body) from Adipose tissue (Fat cells) involves the least risk. Adipose tissue (fat cells) is one of the richest sources of MSCs. When compared to bone marrow, there are more than 500 times more stem cells in 1 gram of fat when compared to 1 gram of aspirated bone marrow.

New England Stem Cell Treatment Center NESCTC has the technology to extract stem cells from your fat cells. Under investigational protocols, these cells can be deployed to treat a number of degenerative conditions and diseases. NESCTC in collaboration with New England Center for Hair Restoration is pioneering deploying stem cells to treat thinning hair and hair loss.

Baldness

Hair follicles also contain stem cells, and some researchers predict research on these follicle stem cells may lead to successes in treating baldness through an activation of the stem cells progenitor cells. This therapy is expected to work by activating already existing stem cells on the scalp. Later therapy may be able to simply signal follicle stem cells to give off chemical signals to nearby follicle cells which have shrunk during the aging process, which in turn respond to these signals by regenerating and once again making healthy hair. Most recently, Dr. Aeron Potter of the University of California has claimed that stem-cell therapy led to a significant and visible improvement in follicular hair growth.

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Posted: September 6, 2014 at 4:56 am

There is no Rhode Island law that specifically restricts the use of human adult or embryonic stem cells for research purposes. The Rhode Island law that does restrict some uses of human cells explicitly permits research as long as the research is not for the purposes of cloning an entire human beingwhich is not part of stem cell research.

Starting in 2003 and continuing every year thereafter, bills were introduced that would have explicitly allowed all forms of stem cell research and created a procedure for unused embryos as a result of in vitro fertilization treatments to be donated for the purpose of stem cell research. These bills were sponsored in the House by Representative Edith Ajello, and in the Senate by Senator Rhoda Perry. A 2007 version of the bill, 2007 H-6082, was introduced again but failed to pass.

In 2006, a resolution sponsored by Representative Eileen Naughton was passed, creating a special House commission to promote and develop a nationally recognized cord blood program for the future of disease management in Rhode Island. That commission began meeting in February of 2007. In 2007, a resolution sponsored by Representative Naughton was passed creating the Rhode Island House of Representatives Regenerative Medicine and Research Advisory Study Commission.

In 2007, Lt. Governor Elizabeth Roberts released a report entitled Discovering Rhode Islands Stem Cell Future: Charting the Course Toward Health and Prosperity, outlining the potential that stem cell research holds for reducing human suffering and supporting economic growth in Rhode Island.

Contacts for IASCR: Adriana Thomas, Policy Analyst, Rhode Island House of Representatives, and Eli Zupnick, Policy Analyst, Office of the Lt. Governor

Excerpt from:Rhode Island | Interstate Alliance on Stem Cell Research

Posted: August 22, 2014 at 6:02 am

Rhode Island Stem Cell Therapy Worldstemcells.com is one of the leading stem cell therapy and treatment providers for residents of Rhode Island and across the nation. Our cutting edge technology and compassionate staff truly set us apart from the competition. We are a US based company that understands your needs and concerns when looking for a stem cell treatment center. Our treatment center is located in Cancun, Mexico.

Conditions we treat include but not limited to:

Getting Started With Your Stem Cell Therapy and Treatments Here at World Stem Cells LLC we try to make the process of receiving stem cell transplants as easy as possible. We will help you figure out what your needs are and help you reach your goals as fast as possible. Follow the steps below on what to do.

Option 1 1.) Go to any page on our website and fill out the contact form. 2.) Fill in the required information and select the condition you would like to treat with stem cell therapy. 3.) Be sure to include any special information in the comments section. 4.) Click the submit button and we will contact you in a timely manner. 5.) Thats it, youre done!!!

REQUEST INFORMATION NOW!

Option 2

Call 800-234-1693 and speak with a representative regarding your stem cell therapy needs and requirements.

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Rhode Island Stem Cell Therapy | Stem Cell Treatments

Posted: at 6:02 am

Thousands of people suffer from diseases treatable with marrow or blood stem cell transplants. The National Marrow Donor Program finds donors for patients who don't have a match in their family.

First, volunteer. Join the Registry if you are 18-44 years old, in good health, and willing to give a swab of cheek cells.

Next, if you are a match, give blood samples to confirm it.

Then, you make a decision to give after an information session and a physical exam.

A Marrow Donation is donated in a hospital. After anesthesia is given, doctors remove a small amount of marrow from the back of the hip bones with a needle and syringe. Recovery is quick, though most donors have some bone pain and aches for several days or a few weeks. The marrow given naturally replenishes itself in four to six weeks. This method is selected 25 percent of the time.

A Peripheral Blood Stem Cell Donation is a special type of blood donation given at the Rhode Island Blood Center. Five daily injections of a stem cell growth factor are given to donors to increase the number of stem cells released from the marrow into the blood stream. Then an apheresis blood donation is made. Donors can experience bone pain as a result of receiving the growth factor. Recovery is quick, however, just one or two days after the donation is made. This method is selected 75 percent of the time.

For more information on joining the Be The Match Registry or to sponsor a marrow registration drive, please call 401-248-5720 or email marrow@ribc.org. Additional information is also available on http://www.marrow.org.

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Marrow Donor Program - Rhode Island Blood Center

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Orthopedic Stem Cell Therapy in Utah for Painful Joints

Posted: September 7, 2019 at 4:26 pm

John D. Sonnenberg, M.D.

Stem Cell Therapy is a one of the most exciting areas in all of modern medicine. The treatment of joint pain andinjuries appears to be on the verge of a revolution. Leading this revolution arethe continued discoveries and development of Orthopedic Stem Cell Therapys healing capabilities. At South Valley OrthoMed, we offer the latest technology in orthopedic stem cell treatments to the entire Salt Lake Valley. With more than 35 years of orthopedic experience, our patients receive treatment by the most qualified and capable hands around, namely, experienced, board-certified orthopedic surgeons.

Stem cells are, in short, natures original construction crew. Naturally produced by the human body, stem cells possess the incredible ability to change and adapt into more specializedcell types.Think of them as growth, or developmental cells, still in their infancy. In Stem Cell Therapy these multi-talented cells are injected into a specific, damaged area of the body. The cells are then able to grow and reproduce themselves. They mature and contribute to their surrounding environment, particularly in repairing damaged tissue. When stem cells enter damaged tissue, they receive signals that instruct them to differentiate. Damaged tendons, ligaments, bones, cartilage, muscle andeven damaged skin, are all treatable with stem cells.

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Orthopedic Stem Cell Therapy in Utah for Painful Joints

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Molecular genetics | biology | Britannica.com

Posted: September 7, 2019 at 4:25 pm

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biology

THIS IS A DIRECTORY PAGE. Britannica does not currently have an article on this topic.

The data accumulated by scientists of the early 20th century provided compelling evidence that chromosomes are the carriers of genes. But the nature of the genes themselves remained a mystery, as did the mechanism by which they exert their influence. Molecular geneticsthe study

the early 20th century when molecular geneticists began conducting research using model organisms such as Drosophila melanogaster (also called the vinegar fly or fruit fly) that provided a more comprehensive view of the complexities of genetic transmission. For example, molecular genetics studies demonstrated that two alleles can be codominant (characteristics

Although overlapping with biochemical techniques, molecular genetics techniques are deeply involved with the direct study of DNA. This field has been revolutionized by the invention of recombinant DNA technology. The DNA of any gene of interest from a donor organism (such as a

Molecular genetics is the study of the molecular structure of DNA, its cellular activities (including its replication), and its influence in determining the overall makeup of an organism. Molecular genetics relies heavily on genetic engineering (recombinant DNA technology), which can be used to

comparative embryology, and molecular genetics. Studies of the molecular structure of genes and of the geographic distribution of flora and fauna are also useful. The fossil record is often used to determine the phylogeny of groups containing hard body parts; it is also used to date divergence times of

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Molecular genetics | biology | Britannica.com

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New Hampshire Stem Cells | Stem Cell TV

Posted: September 7, 2019 at 4:23 pm

In 2014, during a speech in Manchester, Amanda Grappone Osmer made a startling admission.

I know why you hate me, she began, when it came her time to speak at TEDx Amoskeag Millyard. You all have memories of someone like me that takes you back to a time and place that you wish you didnt have to think about.

Your palms start to sweat. Your stomach is in a knot. Like me, your heart races. You just have an overall feeling of dread.

Mentally, you start to make a tally when you see me coming of all the ways you might get ripped off.

She describes further this experience with her at its center.

When you see me, you load up for bear. Because you know you need to, just to get through our conversation, she says.

You hate me because I am a car salesman. A fourth-generation car salesman.

And with a deep breath, she adds, I understand.

Osmers speech spoke to a stereotypical experience someone might have purchasing a car, an experience that she likened to being under the ether and one that her companys philosophy seeks to counter. Her personal mission and that of Grappone Automotive Group in Bow, for which she is CEO, moves well past the showroom to all aspects of the business, employee relationships and the manner in which she leads an engaged community life.

The business mission: Dedication to building lifelong relationships with our team members, guests and community by serving with integrity, kindness and respect.

And ingrained among her personal objectives is being a little bit better than the day before.

Osmer, the keynote speaker for The Keene Sentinels Extraordinary Women Awards on Aug. 24, graduated from the University of New Hampshire with a degree in humanities. In her teens, she worked at her familys dealership, which was started by her great-grandparents in Concord in 1924 as a Gulf service station. It is now five dealerships. But, despite her early work at the dealership, Osmer didnt envision a future for herself in the cars.

In 2001, after school and marriage, she moved to the West Coast, to the North Bay region of San Francisco. Her marriage ended after a short time, leaving her uncertain what to do next. She applied for all sorts of jobs with no luck, she says. Needing something and knowing something about cars, she found herself selling for Lexus of Marin.

I had never sold anything in my life, she says from her second-floor office at Grappones Toyota franchise, not far from the end of Interstate 89. Her notion of sales, she says, was all wrong, and she learned, You have to be nice to people and honest, and you will earn their business.

Three years later, she was back at her family dealership, in charge of fixed operations service, paint and collision. She described this as the hardest job of my life.

It was difficult to find technicians who met company standards, and there were myriad other workforce challenges, not the least of which is that few women run collision and service centers.

I knew nothing about that world, she recalls. It was constant stress.

But it was in this role that she discovered new ways of doing things that would change her and the company she would come to run. She found a mentor in Jeffrey Liker, the author of The Toyota Way, a best-seller at more than 650,000 copies and translated into 27 languages.

Liker, with whom Osmer corresponds, is professor of industrial and operations engineering at the University of Michigan and has written extensively about how Toyotas manufacturing processes employed principles to reduce waste, boost efficiency and create collaborative workforces to solve problems. He has also profiled other companies using these strategies and measurements, first pioneered by W. Edwards Deming in post-World War II Japan.

I fell in love with lean manufacturing, says Osmer, referring to the umbrella term under which these principles exist.

She opens Likers book frequently; her copy is dog-eared, heavily highlighted and fingerprinted and never far from reach. There are, in the lean world, seven categories of waste transport, inventory, motion, waiting, overproduction, over-processing and defects.

Osmer considers it one of her lifes highlights being invited to speak at the headquarters of Dupont in Delaware at a gathering of collision center specialists a conference at which Liker was speaking, too.

Shes asked if Grappone is an efficient operation.

Its a goal, she says candidly, referring to a never-ending focus on continuous improvement.

From the service operation, Osmer was promoted to COO and director of sales. The sales process was going through a similar evolution, she says.

We had peeled away from the current (traditional) way of doing things, she says, referring to the industry standard of commission-based selling. We had to figure out what is our way I really started to notice that we didnt have anyone recognizing the human experience.

The company hired a director of corporate potential a key decision and embarked on strategic planning that led to an unusual, if not dramatically different approach to business. Its primary commitment, she says, is to Grappones 340 employees. They come first in the mission statement by design. Second, the company seeks lifelong relationships with customers and believes this is best achievable if the sales and service experience is not one of negotiation. This, she says, creates integrity and expectations of consistent treatment. Theres a set price for everything, including financing terms. Everyone pays the same, removing the ether to which she referred in her TEDx speech.

Her sales team does not operate on commissions.

It didnt make sense to race to the bottom on pricing, she says.

Having Toyota as a flagship franchise was helpful; expectations of franchises are reasonable, she says, allowing room for Grappones way.

Always trying to be less wasteful as a company, Osmer said an eighth measure of waste also became a Grappone focus the waste of human creativity. Maybe more than any of the other principles, Osmer emphasizes a workplace that allows innovation to occur. As she describes ways this has been manifested, Ron Malachi, the companys inventory pricing specialist, walks by her office.

He ducks in when asked and rattles off several recent problems a team of folks has solved, including storing extra car inventory at a nearby indoor sports facility.

They get some income, and we get a place (to keep the cars), he says.

Osmer is one of five children born to Robert and Beverly Grappone. Her younger brother, Greg, was her only sibling to be part of the business, eventually becoming the groups chief information officer.

Greg, who had health challenges early in his life, developed cutaneous T-cell lymphoma in his 30s. He found he needed a blood stem cell transplant when the disease turned aggressive.

Osmer was a match for the transplant. Treatment involved eradicating Gregs immune system and injecting new stem cells through a transfusion of Osmers blood. The cancer was killed, but a gruesome side effect graft versus host disease took hold. Osmer described the horrific condition that transpired as one that literally hardened his tissues.

Greg died in 2015, leaving behind a wife and a two-year-old daughter.

In his name, Osmer works on a project that would develop a six-mile abandoned rail line into a new bike and walking path that connects to the Northern Rail trail and would link Concord to Lebanon. It is but one page in her deep portfolio of community work.

She says this involvement in social causes is informed by her familys work.

We were always taught its not about us, she says. Dad just didnt get hung up on material things. I dont get upset when I dont have more things. Its better to express me through how much I help people.

She sees herself as dedicated to serving a lot of people, and it starts with the employees, as the mission suggests.

People need to feel safe; psychological safety, physical safety and having flexibility, she says, describing how the company culture is modeled.

In such an environment, creativity is unleashed, efficiencies are found and people are retained. That environment includes an immaculate, welcoming Toyota dealership building that features a grand piano on its second floor a gift to Osmer from her grandfather.

So, its not a surprise that her team of six directors has more than 140 years of collective service to Grappone.

Away from the dealership, Osmers list of community-service positions is extensive and includes: board member, New Hampshire Public Broadcasting System; corporator, Canterbury Shaker Village; board member, The Endowment for Health; member, Partners for Community Wellness; member, New Hampshire Lemon Law Board; advisory member, Spark New Hampshire; advisory member, Stay Work Play New Hampshire; and advisory member, New Hampshire Charitable Foundations New Hampshire Tomorrow Initiative.

Recently, she became involved in President Donald Birx move to reorganize Plymouth State University into seven educational clusters, beginning this fall. They are: arts and technology; education, democracy and social change; exploration and discovery; health and human enrichment; innovation and entrepreneurship; justice and security; and tourism, environment and sustainable development.

I try to go where I can be most useful, she says, adding she prefers, in many cases, serving one term on a board rather than more to allow broader service.

Osmer lives with her husband, Tom, and three children (two girls and a boy) in a log home in Canterbury. The community, known for its Shaker history, suits her in many ways, from the caring she can expect from the Canterbury Library staff if she drops her son off some afternoon, to the wooded setting that allows her to indulge in trail running, to the neighborly warmth of the Canterbury Fair, recently held.

And, its just the right setting to play her banjo, her instrument of choice.

Osmers is a life being well lived and one seemingly grounded in the words she used to finish her TEDx speech.

So, this is not just about car sales. Its not just about a fourth-generation family business in Bow Junction, New Hampshire, she says. Ask yourselves. Do integrity, kindness and respect form the foundation of all of your relationships, with the people you love the most, with the people you work with, with the people you meet every day? Do they?

If they dont, dont worry about it, she says. Just know that you are under the ether with all of the rest of us. And its time to wake up.

See more here:Amanda Grappone Osmer breaks down car sales stereotypes with focus on kindness, integrity - The Keene Sentinel

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New Hampshire Stem Cells | Stem Cell TV

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Molecular Medicine (formerly Molecular & Cellular Biology)

Posted: June 3, 2019 at 12:45 am

Welcome!

The Interdisciplinary Graduate Program in Molecular Medicineis one of the first cross-departmental graduate programs at The University of Iowa. It was founded by John Menninger in 1974, and funded by a National Research Service Award Training Program in Molecular Medicine from 1975-1992. This initial Program did not admit students or grant degrees. Instead, after their first year of graduate study, students from various departments were chosen and awarded stipends based on merit. Similarly to today, the students and faculty met for a weekly seminar, designed to inform trainees about the variety of research that was of interest to cell and molecular biologists, to give trainees practice in presenting their research to a critical audience, and to provide a social connection for trainees who were working in various departments. In 1992, the Molecular Biology Graduate Program was formalized into a degree-granting PhD program, and in 2005, the program came full circle with a name change and a new NIH training grant in Molecular and Cellular Biology.

Today, the Interdisciplinary Graduate Program in Molecular and Cellular Biology still fosters the interdisciplinary efforts of a diverse group of investigatorsboth faculty and studentswith common interests in molecular and cellular biology. Currently the program faculty represent the departments of Anatomy and Cell Biology, Biochemistry, Biological Sciences, Chemistry, Dows Institute for Dental Research,Internal Medicine, Microbiology, Molecular Physiology & Biophysics, Neurology, Obstetrics and Gynecology, Ophthalmology & Visual Sciences, Otolaryngology, Pathology, Pediatrics, Pharmacology, Psychiatry,Radiation Oncology, and Surgery.The program actively recruits new students with diverse research interests.

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Molecular Medicine (formerly Molecular & Cellular Biology)

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