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Diabetes mellitus type 1 – Wikipedia

Posted: January 5, 2019 at 7:43 am

Diabetes type1SynonymsT1D, insulin-dependent diabetes,[1] juvenile diabetes[2]A blue circle, the symbol for diabetes.[3]PronunciationSpecialtyEndocrinologySymptomsFrequent urination, increased thirst, increased hunger, weight loss[4]ComplicationsDiabetic ketoacidosis, nonketotic hyperosmolar coma, poor healing, cardiovascular disease, damage to the eyes[2][4][5]Usual onsetRelatively short period of time[1]DurationLong term[4]CausesNot enough insulin[4]Risk factorsFamily history, celiac disease[5][6]Diagnostic methodBlood sugar, A1C[5][7]PreventionUnknown[4]TreatmentInsulin, diabetic diet, exercise[1][2]Frequency~7.5% of diabetes cases[8]

Diabetes mellitus type1, also known as type 1 diabetes, is a form of diabetes mellitus in which very little or no insulin is produced by the pancreas.[4] Before treatment this results in high blood sugar levels in the body.[1] The classic symptoms are frequent urination, increased thirst, increased hunger, and weight loss.[4] Additional symptoms may include blurry vision, feeling tired, and poor wound healing.[2] Symptoms typically develop over a short period of time.[1]

The cause of type 1 diabetes is unknown.[4] However, it is believed to involve a combination of genetic and environmental factors.[1] Risk factors include having a family member with the condition.[5] The underlying mechanism involves an autoimmune destruction of the insulin-producing beta cells in the pancreas.[2] Diabetes is diagnosed by testing the level of sugar or glycated hemoglobin (HbA1C) in the blood.[5][7] Type 1 diabetes can be distinguished from type 2 by testing for the presence of autoantibodies.[5]

There is no known way to prevent type 1 diabetes.[4] Treatment with insulin is required for survival.[1] Insulin therapy is usually given by injection just under the skin but can also be delivered by an insulin pump.[9] A diabetic diet and exercise are important parts of management.[2] If left untreated, diabetes can cause many complications.[4] Complications of relatively rapid onset include diabetic ketoacidosis and nonketotic hyperosmolar coma.[5] Long-term complications include heart disease, stroke, kidney failure, foot ulcers and damage to the eyes.[4] Furthermore, complications may arise from low blood sugar caused by excessive dosing of insulin.[5]

Type1 diabetes makes up an estimated 510% of all diabetes cases.[8] The number of people affected globally is unknown, although it is estimated that about 80,000 children develop the disease each year.[5] Within the United States the number of people affected is estimated at one to three million.[5][10] Rates of disease vary widely with approximately 1 new case per 100,000 per year in East Asia and Latin America and around 30 new cases per 100,000 per year in Scandinavia and Kuwait.[11][12] It typically begins in children and young adults.[1]

The classical symptoms of type 1 diabetes include: polyuria (increased urination), polydipsia (increased thirst), dry mouth, polyphagia (increased hunger), fatigue, and weight loss.[4]

Many type 1 diabetics are diagnosed when they present with diabetic ketoacidosis. The signs and symptoms of diabetic ketoacidosis include dry skin, rapid deep breathing, drowsiness, increased thirst, frequent urination, abdominal pain, and vomiting.[14]

About 12 percent of people with type 1 diabetes have clinical depression.[15]

About 6 percent of people with type 1 diabetes have celiac disease, but in most cases there are no digestive symptoms[6][16] or are mistakenly attributed to poor control of diabetes, gastroparesis or diabetic neuropathy.[16] In most cases, celiac disease is diagnosed after onset of type 1 diabetes. The association of celiac disease with type 1 diabetes increases the risk of complications, such as retinopathy and mortality. This association can be explained by shared genetic factors, and inflammation or nutritional deficiencies caused by untreated celiac disease, even if type 1 diabetes is diagnosed first.[6]

Some people with type 1 diabetes experience dramatic and recurrent swings in glucose levels, often occurring for no apparent reason; this is called "unstable diabetes","labile diabetes" or "brittle diabetes".[17] The results of such swings can be irregular and unpredictable hyperglycemias, sometimes involving ketoacidosis, and sometimes serious hypoglycemias. Brittle diabetes occurs no more frequently than in 1% to 2% of diabetics.[17]

Type 1 diabetes is associated with alopecia areata (AA).[18] Type 1 diabetes is also more common in the family members of people with AA.[19]

The cause of type 1 diabetes is unknown.[4] A number of explanatory theories have been put forward, and the cause may be one or more of the following: genetic susceptibility, a diabetogenic trigger, and exposure to an antigen.[20]

Type1 diabetes is a disease that involves many genes. The risk of a child developing type 1 diabetes is about 5% if the father has it, about 8% if a sibling has it, and about 3% if the mother has it.[21] If one identical twin is affected there is about a 40% chance the other will be too.[22][23] Some studies of heritability have estimated it at 80 to 86%.[24][25]

More than 50 genes are associated with type 1 diabetes. Depending on locus or combination of loci, they can be dominant, recessive, or somewhere in between. The strongest gene, IDDM1, is located in the MHC Class II region on chromosome 6, at staining region 6p21. Certain variants of this gene increase the risk for decreased histocompatibility characteristic of type1. Such variants include DRB1 0401, DRB1 0402, DRB1 0405, DQA 0301, DQB1 0302 and DQB1 0201, which are common in North Americans of European ancestry and in Europeans.[26] Some variants also appear to be protective.[26]

There is on the order of a 10-fold difference in occurrence among Caucasians living in different areas of Europe, and people tend to acquire the disease at the rate of their particular country.[20] Environmental triggers and protective factors under research include dietary agents such as proteins in gluten,[27] time of weaning, gut microbiota,[28] viral infections,[29] and bacterial infections like paratuberculosis.[30]

Some chemicals and drugs selectively destroy pancreatic cells.Pyrinuron (Vacor), a rodenticide introduced in the United States in 1976, selectively destroys pancreatic beta cells, resulting in type 1 diabetes after accidental poisoning.[31] Pyrinuron was withdrawn from the U.S. market in 1979 and it is not approved by the Environmental Protection Agency for use in the U.S.[32] Streptozotocin (Zanosar), an antineoplastic agent, is selectively toxic to the beta cells of the pancreatic islets. It is used in research for inducing type 1 diabetes on rodents[33] and for treating metastatic cancer of the pancreatic islet cells in patients whose cancer cannot be removed by surgery.[34] Other pancreatic problems, including trauma, pancreatitis, or tumors (either malignant or benign) can also lead to loss of insulin production.

The pathophysiology in diabetes type 1 is a destruction of beta cells in the pancreas, regardless of which risk factors or causative entities have been present.

Individual risk factors can have separate pathophysiological processes to, in turn, cause this beta cell destruction. Still, a process that appears to be common to most risk factors is an autoimmune response towards beta cells, involving an expansion of autoreactive CD4+ T helper cells and CD8+ T cells, autoantibody-producing B cells and activation of the innate immune system.[26][35]

After starting treatment with insulin a person's own insulin levels may temporarily improve.[36] This is believed to be due to altered immunity and is known as the "honeymoon phase".[36]

Diabetes mellitus is characterized by recurrent or persistent hyperglycemia, and is diagnosed by demonstrating any one of the following:[39]

About a quarter of people with new type1 diabetes have developed some degree of diabetic ketoacidosis (a type of metabolic acidosis which is caused by high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids) by the time the diabetes is recognized. The diagnosis of other types of diabetes is usually made in other ways. These include ordinary health screening, detection of hyperglycemia during other medical investigations, and secondary symptoms such as vision changes or unexplained fatigue. Diabetes is often detected when a person suffers a problem that may be caused by diabetes, such as a heart attack, stroke, neuropathy, poor wound healing or a foot ulcer, certain eye problems, certain fungal infections, or delivering a baby with macrosomia or hypoglycemia (low blood sugar).[citation needed]

A positive result, in the absence of unequivocal hyperglycemia, should be confirmed by a repeat of any of the above-listed methods on a different day. Most physicians prefer to measure a fasting glucose level because of the ease of measurement and the considerable time commitment of formal glucose tolerance testing, which takes two hours to complete and offers no prognostic advantage over the fasting test.[41] According to the current definition, two fasting glucose measurements above 126mg/dl (7.0mmol/l) is considered diagnostic for diabetes mellitus.[citation needed]

In type1, pancreatic beta cells in the islets of Langerhans are destroyed, decreasing endogenous insulin production. This distinguishes type1's origin from type2. Type 2 diabetes is characterized by insulin resistance, while type 1 diabetes is characterized by insulin deficiency, generally without insulin resistance. Another hallmark of type 1 diabetes is islet autoreactivity, which is generally measured by the presence of autoantibodies directed towards the beta cells.[citation needed]

The appearance of diabetes-related autoantibodies has been shown to be able to predict the appearance of diabetes type 1 before any hyperglycemia arises, the main ones being islet cell autoantibodies, insulin autoantibodies, autoantibodies targeting the 65-kDa isoform of glutamic acid decarboxylase (GAD), autoantibodies targeting the phosphatase-related IA-2 molecule, and zinc transporter autoantibodies (ZnT8).[20] By definition, the diagnosis of diabetes type 1 can be made first at the appearance of clinical symptoms and/or signs, but the emergence of autoantibodies may itself be termed "latent autoimmune diabetes". Not everyone with autoantibodies progresses to diabetes type 1, but the risk increases with the number of antibody types, with three to four antibody types giving a risk of progressing to diabetes type 1 of 60100%.[20] The time interval from emergence of autoantibodies to clinically diagnosable diabetes can be a few months in infants and young children, but in some people it may take years in some cases more than 10 years.[20] Islet cell autoantibodies are detected by conventional immunofluorescence, while the rest are measured with specific radiobinding assays.[20]

Type1 diabetes is not currently preventable.[42] Some researchers believe it might be prevented at the latent autoimmune stage, before it starts destroying beta cells.[26]

Cyclosporine A, an immunosuppressive agent, has apparently halted destruction of beta cells (on the basis of reduced insulin usage), but its kidney toxicity and other side effects make it highly inappropriate for long-term use.[26]

Anti-CD3 antibodies, including teplizumab and otelixizumab, had suggested evidence of preserving insulin production (as evidenced by sustained C-peptide production) in newly diagnosed type 1 diabetes patients.[26] A probable mechanism of this effect was believed to be preservation of regulatory T cells that suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self-antigens.[26] The duration of the effect is still unknown, however.[26] In 2011, Phase III studies with otelixizumab and teplizumab both failed to show clinical efficacy, potentially due to an insufficient dosing schedule.[43][44]

An anti-CD20 antibody, rituximab, inhibits B cells and has been shown to provoke C-peptide responses three months after diagnosis of type 1 diabetes, but long-term effects of this have not been reported.[26]

Some research has suggested breastfeeding decreases the risk in later life[45][46] and early introduction of gluten-containing cereals in the diet increases the risk of developing islet cell autoantibodies;[47] various other nutritional risk factors are being studied, but no firm evidence has been found.[48]Giving children 2000IU of vitamin D daily during their first year of life is associated with reduced risk of type1 diabetes, though the causal relationship is obscure.[49]

Children with antibodies to beta cell proteins (i.e. at early stages of an immune reaction to them) but no overt diabetes, and treated with niacinamide (vitamin B3), had less than half the diabetes onset incidence in a seven-year time span than did the general population, and an even lower incidence relative to those with antibodies as above, but who received no niacinamide.[50]

People with type 1 diabetes and undiagnosed celiac disease have worse glycaemic control and a higher prevalence of nephropathy and retinopathy. Gluten-free diet, when performed strictly, improves diabetes symptoms and appears to have a protective effect against developing long-term complications. Nevertheless, dietary management of both these diseases is challenging and these patients have poor compliance of the diet.[51]

Diabetes is often managed by a number of health care providers including a dietitian, nurse educator, eye doctor, endocrinologist, and podiatrist.[52]

A low-carbohydrate diet, exercise, and medications are useful in type 1 DM.[53] There are camps for children to teach them how and when to use or monitor their insulin without parental help.[54] As psychological stress may have a negative effect on diabetes, a number of measures have been recommended including: exercising, taking up a new hobby, or joining a charity, among others.[55]

Injections of insulin either via subcutaneous injection or insulin pump are necessary for those living with type 1 diabetes because it cannot be treated by diet and exercise alone.[56] Insulin dosage is adjusted taking into account food intake, blood glucose levels and physical activity.

Untreated type1 diabetes can commonly lead to diabetic ketoacidosis which is a diabetic coma which can be fatal if untreated.[57] Diabetic ketoacidosis can cause cerebral edema (accumulation of liquid in the brain). This is a life-threatening issue and children are at a higher risk for cerebral edema than adults, causing ketoacidosis to be the most common cause of death in pediatric diabetes.[58]

Treatment of diabetes focuses on lowering blood sugar or glucose (BG) to the near normal range, approximately 80140mg/dl (4.47.8mmol/l).[59] The ultimate goal of normalizing BG is to avoid long-term complications that affect the nervous system (e.g. peripheral neuropathy leading to pain and/or loss of feeling in the extremities), and the cardiovascular system (e.g. heart attacks, vision loss). This level of control over a prolonged period of time can be varied by a target HbA1c level of less than 7.5%.[5]

There are four main types of insulin: rapid acting insulin, short-acting insulin, intermediate-acting insulin, and long-acting insulin. The rapid acting insulin is used as a bolus dosage. The action onsets in 15 minutes with peak actions in 30 to 90 minutes. Short acting insulin action onsets within 30 minutes with the peak action around 2 to 4 hours. Intermediate acting insulin action onsets within one to two hours with peak action of four to 10 hours. Long-acting insulin is usually given once per day. The action onset is roughly 1 to 2 hours with a sustained action of up to 24 hours. Some insulins are biosynthetic products produced using genetic recombination techniques; formerly, cattle or pig insulins were used, and even sometimes insulin from fish.[60]

People with type 1 diabetes always need to use insulin, but treatment can lead to low BG (hypoglycemia), i.e. BG less than 70mg/dl (3.9mmol/l). Hypoglycemia is a very common occurrence in people with diabetes, usually the result of a mismatch in the balance among insulin, food and physical activity. Symptoms include excess sweating, excessive hunger, fainting, fatigue, lightheadedness and shakiness.[61] Mild cases are self-treated by eating or drinking something high in sugar. Severe cases can lead to unconsciousness and are treated with intravenous glucose or injections with glucagon. Continuous glucose monitors can alert patients to the presence of dangerously high or low blood sugar levels, but technical issues have limited the effect these devices have had on clinical practice.[citation needed]

As of 2016 an artificial pancreas looks promising with safety issues still being studied.[62] In 2018 they were deemed to be relatively safe.[63]

In some cases, a pancreas transplant can restore proper glucose regulation. However, the surgery and accompanying immunosuppression required may be more dangerous than continued insulin replacement therapy, so is generally only used with or some time after a kidney transplant. One reason for this is that introducing a new kidney requires taking immunosuppressive drugs such as cyclosporine, which allows the introduction of a new pancreas to a person with diabetes without any additional immunosuppressive therapy. However, pancreas transplants alone may be beneficial in people with extremely labile type1 diabetes mellitus.[64]

Islet cell transplantation may be an option for some people with type 1 diabetes that are not well controlled with insulin.[65] Difficulties include finding donors that are compatible, getting the new islets to survive, and the side effects from the medications used to prevent rejection.[65][66] Success rates, defined as not needing insulin at 3 years following the procedure occurred in 44% of people on registry from 2010.[65] In the United States, as of 2016, it is considered an experimental treatment.[66]

Complications of poorly managed type 1 diabetes mellitus may include cardiovascular disease, diabetic neuropathy, and diabetic retinopathy, among others. However, cardiovascular disease[67] as well as neuropathy[68] may have an autoimmune basis, as well. Women with type 1 DM have a 40% higher risk of death as compared to men with type 1 DM.[69] The life expectancy of an individual with type 1 diabetes is 11 years less for men and 13 years less for women.[70]

People with diabetes show an increased rate of urinary tract infection.[71] The reason is bladder dysfunction that is more common in diabetics than in non-diabetics due to diabetic nephropathy. When present, nephropathy can cause a decrease in bladder sensation, which in turn, can cause increased residual urine, a risk factor for urinary tract infections.[72]

Sexual dysfunction in diabetics is often a result of physical factors such as nerve damage and poor circulation, and psychological factors such as stress and/or depression caused by the demands of the disease.[73]

The most common sexual issues in diabetic males are problems with erections and ejaculation: "With diabetes, blood vessels supplying the peniss erectile tissue can get hard and narrow, preventing the adequate blood supply needed for a firm erection. The nerve damage caused by poor blood glucose control can also cause ejaculate to go into the bladder instead of through the penis during ejaculation, called retrograde ejaculation. When this happens, semen leaves the body in the urine." Another cause of erectile dysfunction is reactive oxygen species created as a result of the disease. Antioxidants can be used to help combat this.[74]

Studies find a significant prevalence of sexual problems in diabetic women,[73] including reduced sensation in the genitals, dryness, difficulty/inability to orgasm, pain during sex, and decreased libido. Diabetes sometimes decreases estrogen levels in females, which can affect vaginal lubrication. Less is known about the correlation between diabetes and sexual dysfunction in females than in males.[73]

Oral contraceptive pills can cause blood sugar imbalances in diabetic women. Dosage changes can help address that, at the risk of side effects and complications.[73]

Women with type 1 diabetes show a higher than normal rate of polycystic ovarian syndrome (PCOS).[75] The reason may be that the ovaries are exposed to high insulin concentrations since women with type 1 diabetes can have frequent hyperglycemia.[76]

Women with type 1 diabetes are higher risk for other autoimmune diseases, such as autoimmune thyroid disease, rheumatoid arthritis and lupus.[77][78]

Type1 diabetes makes up an estimated 510% of all diabetes cases[8] or 1122million worldwide.[42] In 2006 it affected 440,000 children under 14 years of age and was the primary cause of diabetes in those less than 10 years of age.[79] The incidence of type 1 diabetes has been increasing by about 3% per year.[79]

Rates vary widely by country. In Finland, the incidence is a high of 57 per 100,000 per year, in Japan and China a low of 1 to 3 per 100,000 per year, and in Northern Europe and the U.S., an intermediate of 8 to 17 per 100,000 per year.[80][81]

In the United States, type 1 diabetes affected about 208,000 youths under the age of 20 in 2015. Over 18,000 youths are diagnosed with Type 1 diabetes every year. Every year about 234,051 Americans die due to diabetes (type I or II) or diabetes-related complications, with 69,071 having it as the primary cause of death.[82]

In Australia, about one million people have been diagnosed with diabetes and of this figure 130,000 people have been diagnosed with type 1 diabetes. Australia ranks 6th-highest in the world with children under 14 years of age. Between 2000 and 2013, 31,895 new cases were established, with 2,323 in 2013, a rate of 1013 cases per 100,00 people each year. Aboriginals and Torres Strait Islander people are less affected.[83][84]

Type 1 diabetes was described as an autoimmune disease in the 1970s, based on observations that autoantibodies against islets were discovered in diabetics with other autoimmune deficiencies.[85] It was also shown in the 1980s that immunosuppressive therapies could slow disease progression, further supporting the idea that type 1 diabetes is an autoimmune disorder.[86] The name juvenile diabetes was used earlier as it often first is diagnosed in childhood.

The disease was estimated to cause $10.5 billion in annual medical costs ($875 per month per diabetic) and an additional $4.4 billion in indirect costs ($366 per month per person with diabetes) in the U.S.[87] In the United States $245 billion every year is attributed to diabetes. Individuals diagnosed with diabetes have 2.3 times the health care costs as individuals who do not have diabetes. One in 10 health care dollars are spent on individuals with diabetes.[82]

Funding for research into type 1 diabetes originates from government, industry (e.g., pharmaceutical companies), and charitable organizations. Government funding in the United States is distributed via the National Institute of Health, and in the UK via the National Institute for Health Research or the Medical Research Council. The Juvenile Diabetes Research Foundation (JDRF), founded by parents of children with type 1 diabetes, is the world's largest provider of charity-based funding for type 1 diabetes research.[citation needed] Other charities include the American Diabetes Association, Diabetes UK, Diabetes Research and Wellness Foundation,[88] Diabetes Australia, the Canadian Diabetes Association.

A number of approaches have been explored to understand causes and provide treatments for type 1.

Data suggest that gliadin (a protein present in gluten) might play a role in the development of type 1 diabetes, but the mechanism is not fully understood.[27][47] Increased intestinal permeability caused by gluten and the subsequent loss of intestinal barrier function, which allows the passage of pro-inflammatory substances into the blood, may induce the autoimmune response in genetically predisposed individuals to type 1 diabetes.[6][47] There is evidence from experiments conducted in animal models that removal of gluten from the diet may prevent the onset of type 1 diabetes[27][89] but there has been conflicting research in humans.[89]

One theory proposes that type1 diabetes is a virus-triggered autoimmune response in which the immune system attacks virus-infected cells along with the beta cells in the pancreas.[29][90] Several viruses have been implicated, including enteroviruses (especially coxsackievirus B), cytomegalovirus, EpsteinBarr virus, mumps virus, rubella virus and rotavirus, but to date there is no stringent evidence to support this hypothesis in humans.[91] A 2011 systematic review and meta-analysis showed an association between enterovirus infections and type 1 diabetes, but other studies have shown that, rather than triggering an autoimmune process, enterovirus infections, as coxsackievirus B, could protect against onset and development of type 1 diabetes.[92]

Gene therapy has also been proposed as a possible cure for type 1 diabetes.[93]

Pluripotent stem cells can be used to generate beta cells but previously these cells did not function as well as normal beta cells.[94] In 2014 more mature beta cells were produced which released insulin in response to blood sugar when transplanted into mice.[95][96] Before these techniques can be used in humans more evidence of safety and effectiveness is needed.[94]

Vaccines to treat or prevent Type 1 diabetes are designed to induce immune tolerance to insulin or pancreatic beta cells.[97] While Phase II clinical trials of a vaccine containing alum and recombinant GAD65, an autoantigen involved in type1 diabetes, were promising, as of 2014 Phase III had failed.[97] As of 2014, other approaches, such as a DNA vaccine encoding proinsulin and a peptide fragment of insulin, were in early clinical development.[97]

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Diabetes mellitus type 1 - Wikipedia

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Stem Cell Mobile Alabama 36607

Posted: January 4, 2019 at 5:50 pm

Stem cell therapy has actually become a popular debate in the worldwide medical scene. This highly controversial treatment has received mixed viewpoints from various stakeholders in the healthcare market and has likewise attracted the attention of politicians, religious leaders and the general population at large. Stem cell treatment is thought about a revolutionary treatment for people experiencing a large range of degenerative conditions. Some typical concerns regarding this therapy are responded to listed below.

Stem cells can be described as blank state or non-specialized cells that have the ability to become specialized cells in the body such as bone, muscle, nerve or organ cells. This suggests that these unique cells can be used to regrow or establish a vast array of broken cells and tissues in the body. Stem cell therapy is therefore a treatment that targets at accomplishing tissue regrowth and can be utilized to treat health conditions and health problems such as osteoarthritis, degenerative disc illness, spine injury, muscular degeneration, motor nerve cell illness, ALS, Parkinsons, cardiovascular disease and much more.

Stem cells can be extracted from a young embryo after conception. These stem cells are commonly described as embryonic stem cells. After the stem cells are extracted from the embryo, the embryo is terminated. This is generally one of the significant causes of controversy in the field of stem cell research study. Many individuals suggest that termination of an embryo is dishonest and unacceptable.

Stem cells can still be gotten through other ways as they can be found in the blood, bone marrow and umbilical cables of adult people. Normal body cells can also be reverse-engineered to become stem cells that have actually restricted abilities.

Being a treatment that is still under studio, stem cell therapy has actually not been totally accepted as a feasible treatment choice for the above discussed health conditions and illnesses. A lot of research is currently being carried out by scientists and medical specialists in numerous parts of the world to make this treatment sensible and effective. There are however different restrictions imposed by federal governments on research including embryonic stem cells.

Presently, there havent been lots of case studies carried out for this type of treatment. However, with the few case studies that have actually been carried out, among the major concerns that has been raised is the increase in a clients risk of establishing cancer. Cancer is caused by the quick multiplication of cells that tend not to die so easily. Stem cells have actually been connected with comparable growth elements that may result in formation of tumors and other cancerous cells in clients.

New research study has actually nevertheless shown promise as researchers target at developing stem cells that do not form into tumors in later treatment stages. These stem cells can therefore effectively transform into other types of specialized cells. This treatment is for that reason worth investigating into as numerous clients can gain from this innovative treatment.

Find a stem cell doctor in Mobile AL 36607

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Stem Cell Mobile Alabama 36607

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Utah Stem Cells – Salt Lake City, UT – Yelp

Posted: January 4, 2019 at 5:46 pm

Specialties

We focus entirely on treatments that will help you feel stronger, with pain free joints, better mood, and a more beautiful appearance. You will look great and feel even better.

Established in 2015.

Utah Stem Cells was founded for the purpose of developing a new and exciting concept in a medical wellness center. Utilizing the latest advancements in stem cell technology, all of our services are specifically designed to enhance the quality of your life. We focus entirely on treatments that will help you feel stronger, with pain free joints, better mood, and a more beautiful appearance. You will look great and feel even better.

Dr. Bill Cimikoski, Medical Director of Utah Stem Cells, is a Medical Toxicologist that specializes in Stem Cell Joint Regeneration-a foremost authority featured on HealthLine TV and ABC's Good 4 Utah. Assisted by experienced and trained nurses and physician assistants, Dr Bill offers the treatments that can benefit you the most, while making sure that from a toxicology perspective won't hurt in the long term.

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Utah Stem Cells - Salt Lake City, UT - Yelp

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Stem Cell Hair Treatment for Hair Loss | Stem Cell Hair Growth

Posted: January 3, 2019 at 2:46 am

Stem Cell Therapy as a Treatment for Hair Loss

Adipose-Derived Stem Cells have shown to be an effective regenerative treatment for hair loss. Stem Cell Hair Therapy is a non-surgical, therapeutic hair restoration procedure that offers a more natural alternative to surgical hair transplants. Tampa Bay Hair Restoration uses adipose-derived stem cells to stimulate follicular hair growth and reverse the effects of hair loss.

Dr. Michael Markou is a board-certified Doctor of Osteopathy (D.O.) and the leading regenerative surgeon at Tampa Bay Hair Restoration. As an internationally renowned leader in cell regeneration, Dr. Markou was the first physician in Florida to utilize Platelet-Rich Plasma (PRP) and Stem Cells for hair regrowth. In addition to hair restoration, Dr. Markou also uses Stem Cell Therapy to treat orthopedic injuries, sports injuries, osteoarthritis, and chronic pain at his medical center in Clearwater and Tarpon Springs, Florida.

Its important to note that hair loss occurs differently in each person, so individual results vary. Stem Cell Hair Restoration offers a variety of advantages to the average hereditary hair loss patient, including:

The primary purpose of a stem cell is to help repair and replace tissues within the body. Stem cells are undifferentiated cells that have the ability to divide (multiply) into many different cell types. When the cells divide, theyre given the option to continue on as a stem cell or become a specialized cell, such as a red or white blood cell. This is dependent on the adjacent tissues that are in need of repairing. Since these cells are ultimately healers, they pick up where other cells and tissues are lacking.

The two main types of stem cells are embryonic stem cells and somatic stem cells. The embryonic stem cells are derived from embryos, while the somatic stem cells (aka adult stem cells) are derived from adult fat tissue. The adult stem cells are found in bone marrow and fat cells, which is also known as adipose tissue. Here at Tampa Bay Hair Restoration, we only use adipose-derived stem cells for our Stem Cell Hair Treatments. The adipose tissue is easily extracted from the patients own body, and can offer a number of remarkable benefits when used as a treatment for hair loss.

The Adipose Stem Cell Hair Treatment is a non-surgical and minimally invasive procedure that lasts approximately an hour. The hair treatment stimulates and regenerates dormant / damaged hair follicles, allowing for natural hair regrowth and follicle rejuvenation. Stem cells can even protect thinning hair from the further effects of DHT a major influencer of male and female pattern baldness.

Similar to PRP Hair Restoration, Stem Cell Hair Therapyalso extracts rejuvenating cells that have a positive influence on the healing process. However, these growth factors are extracted from the patients fat tissue instead of their blood plasma. Once the adipose tissue has been extracted, the desired stem cells will need to be separated from the fat cells and concentrated using a centrifuge system. These stem cells will be rich in mesenchymal cells and growth factors to enhance cellular healing and tissue repair. The stem cells will then be reintroduced back into the patients recipient site using a very thin syringe. The recipient site is the area that has been affected by hair loss or pattern baldness.

Stem Cell Hair Restoration is very safe due to the fact that the only tissues used in the procedure come directly from the patients own cells. This autologous procedure eliminates the potential of negative side effects commonly associated with transplantations such as rejection, diseases, blood transfusions or immunogenic reactions.

Stem cell injections for hair loss may leave behind a very tiny mark where injections were made, but will be completely healed and undetectable within the next 1 to 5 days.The minimally invasive technique used in Stem Cell Hair Treatment does not require stitches or suturing, which completely removes the potential of any scars caused from the procedure. In fact, Dr. Markou uses stem cell injections during and after more invasive hair transplant procedures to speed up the healing process and assist with any scarring concerns.

Using adipose stem cells as a treatment for hair loss has shown prominent hair regrowth results in both men and women. Its highly recommended for those who are too young for hair transplant surgeryand for those within the earlier stages of the hair loss cycle. Stem Cell Hair Treatment can begin promoting natural hair growth in as little as two to three months. New hair growth can continue over the course of a year, with the most noticeable results usually being seen six months after treatment has been administered. The new hair growth can provide patients with natural, thicker, and fuller results.PRP and Stem Cell Hair Treatment can often be used together to gain even further hair growth results.

Dr. Markou offers Stem Cell Therapy for hair regrowth in Tampa, Florida. As a leader in hair regeneration, Dr. Markou continues to dedicate his time to stem cell research and regenerative medical advancements in order to continue offering only the best hair growth results for his patients. Whether youre looking for Stem Cell Therapy or a combination of hair loss treatments, you can be assured that Dr. Markou will develop a hair restoration plan that ensures the largest amount of new growth with the most natural and undetectable results.

REVITALIZE YOUR HAIR WITH STEM CELLS!

Tampa Bay Hair Restoration helps patients all throughout Florida and the United States find the ideal solution for their hair loss concerns. We are currently offering FREE consultations at our location in Clearwater (Tampa area), Florida. Schedule your consultation today to learn more about our regenerative hair growth treatments, and how they can help revitalize the look and feel of your hair. Make sure to let us know if youre located outside the local Tampa and Orlando area! We can provide you with the most affordable and convenient accommodation information for your travels.

For more information on any of our hair restoration options or if you would like to schedule an appointment, simply fill out the contact form below or give us a call at (727) 446-0608. Dr. Markou will personally respond as soon as possible.

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Epigenetics – Alex Jones

Posted: January 2, 2019 at 9:43 am

What Is Epigenetics?

Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA sequence. Epigenetics: The Death of the Genetic Theory of Disease Transmission (paperback, 592 pages) is the result of decades of research, and its findings could be as critical to our understanding of human health as Pasteur's research in bacteriology. Reading this book will change how you view the relationships between nutrition, genetics and disease. Take control of your health and learn how you can break free from the profit driven modern medical industry.

Dr. Joel "Doc" Wallach has dedicated his life work to identifying connections between nutritional deficiencies and a range of maladies generally thought to be hereditary, including cystic fibrosis and muscular dystrophy. This nexus between nutrition and the genetics of disease and birth defects has been observed in both human and animal pathology and is the central theme of Epigenetics. Wallach has teamed with noted scholars and researchers Dr. Ma Lan and Dr. Gerhard N. Schrauzer to present their far-reaching and enlightening perspectives on disease prevention and cures.

Epigenetics dispels misinformation from the dogma propagated by our current medical institutions and explains why many established doctors are resistant to change. This book is of vital importance to anyone who wants real knowledge about how the human body functions and how to apply that knowledge to our nutritional needs. Epigenetics lays the foundation to healthier, happier lives; for ourselves and for generations to come.

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Is Stem Cell Therapy Covered by Medicare?

Posted: January 1, 2019 at 11:47 am

Stem cell therapy has been a hot topic in the press lately. With more and more medical providers offering stem cell treatments, patients around the country have been wondering, Is Stem Cell Therapy covered by Medicare.

Stem Cell research has shown that its an effective treatment for chronic joint pain and arthritis sufferers and more recent studies are starting to show the benefit for treatment of neurological disorders as well. (M.S., Parkinsons, and Stroke)

So the team at Stem Cell: The Magazine, have put together some information to answer this question of insurance coverage for potential medical enrollees seeking stem cell and regenerative treatments.

So what is the answer to Does Medicare cover Stem Cell therapy?

From the research that we have pulled up regarding Medicare Insurance Coverage for stem cell therapy; medicare does cover stem cell treatments, but not for some of the chronic degenerative conditions that regenerative treatments (stem cell therapy) can help them with.

You can see in this publication from BCBS that stem cell therapy is covered for the following conditions:

INDICATIONS FOR COVERAGE

Section 2.aAllogeneic Hematopoietic Stem Cell Transplantation (HSCT) eligible for coverage in the following:a) The treatment of leukemiab) The treatment of severe combined immunodeficiency disease (SCID) and for the treatment of Wiskott-Aldrich syndrome.ORc) The treatment of Myelodysplastic Syndromes (MDS) pursuant to Coverage with Evidence Development (CED) in the context of a Medicare-approved, prospective clinical study.3. Autologous Stem Cell Transplantation(AuSCT) is eligible for coverage in the following:a) Acute leukemia in remission who have a high probability of relapse and whohave no human leucocyte antigens (HLA)-matched;ORb) Resistant non-Hodgkins lymphomas or those presenting with poor prognosticfeatures following an initial response;ORc) Recurrent or refractory neuroblastoma;ORd) Advanced Hodgkins disease who have failed conventional therapy and have no HLA-matched donor.

You can see that outside of the listed conditions above, Medicare does not cover stem cell therapy for treatments joint conditions or neurological conditions that patients are more commonly seeking treatment for.

In this article, it clearly states that stem cell therapy for the coverage of orthopedic conditions is not covered:

The orthopedic application of stem-cell therapy is not addressed within the stem cell transplantation NCD. (NCD = National Care Determinations)

What this means for any patient that is looking to receive regenerative and stem cell treatments for orthopedic conditions such as:

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Medicare will not cover treatment for these conditions. In fact, most major medical carriers will not provide coverage for these treatments either.

Many chronic joint pain sufferers wonder why Medicare and most major carriers dont provide coverage for these treatments if they are so effective, but there is a simple answer for why this is.

Medicare and most major health insurance are for emergency conditions. Regenerative medicine is still considered an elective treatment, close to wellness care. Insurance carriers are not in the business of providing wellness for coverage for their participants.

We found a great video that explains more about this by John R Hoffman at Arcadia University. In it he describes the challenges of Medicare coverage for Stem Cell Therapy.

Our hope at Stem Cell: The Magazine is that as more and more patients continue to seek out treatment of their orthopedic and neurological conditions using stem cell and regenerative treatments, that Mediare and major health insurances will accept stem cell as the first treatment for these chronic conditions.

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Is Stem Cell Therapy Covered by Medicare? was last modified: October 3rd, 2018 by Stem Cell The Magazine

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Stem Cell Therapy, Amniotic Fluid Injections, Pain Relief

Posted: January 1, 2019 at 11:47 am

Orthopaedic surgeon Dr. Stacie Grossfeld discussing Stem Cell Therapy.

Stem Cell Recruitment Therapy is a safe and effective treatment to helpyour body heal itself. It is typically administered during a normal office visit, through asingle injection. Patients have reported improved pain relief and repair for the following conditions:

Stem Cell injections are conveniently administered through a single injection during a normal office visit. Following the injection, patients are typically able to return to everyday, non-high impact activities within 24 to 48 hours.

What benefits does Stem Cell Recruitment Therapy offer?

For more information about stem cell recruitment therapy, or to make an appointment, callOrthopaedic Specialists at a (502)212-2663. Follow along for more information about stem cell recruitment therapy.

Stem cells for stem cell recruitment therapy are obtained through amniotic fluid. Amniotic fluid contains a multitude of proteins and growth factors. Together they create an extra-cellular matrix to recruit the bodys stem cells to reconstruct and regenerate the injured tissue that is causing pain. Amniotic fluid can repair tissue damage, giving patients with arthritis, joint injuries and soft tissue injuries a treatment option that does not involve pain masking medications or surgery.

The amniotic fluid is obtained during full-term cesarean births from healthy donors who have volunteered their placenta and amniotic fluid. All amniotic fluid is collected aseptically and tested prior to processing and determined to be eligible for transplantation by Donors Suitability Standards established by the AATB and the FDA. The products we use are FDA regulated under the 21 CFR Part 1271 and Section 361 of the Public Health and Service Act.

Stem cells take advantage of the bodys ability to repair itself. With a stem cell injection, your physician injects the amniotic fluid containing stem cells into your body. The amniotic fluid has anti-inflammatory properties, similar to cortisone and steroid shots. However, amniotic fluid goes far beyond the benefits of standard injection therapy.

While cortisone and other drugs only provide temporary pain relief, amniotic fluid actually restores degenerated tissue while providing pain relief. The growth factors in the amniotic fluid may recruit your bodys own stem cells, directly mitigating the repair and the regeneration of healthy tissue. Additionally, amniotic fluid injections contain hyaluronic acid, which lubricates joints and tendons, easing the pain and helping restore mobility.

Stem cells have over 200 growth factors. A growth factor is a proteins or enzyme that can grow cartilage, repair scars, reduce inflammation, take away pain, and grow bone. Astem cell can turn into any type of cell. Basically, it doesnt know what it wants to be when it grows up If you put it into the knee, it turns into the cells in the knee joint, it is an imitator so to speak, adapting to the environment where it is placed.

As we get older our stem cells get older. The amniotic stem cells are much more potent. The other advantage of the amniotic stem cells is that you do not have to have the painful procedure where stem cells are harvested out of your pelvis bone.

Typically it can take three to six weeks for a patient to feel the full effect of stem cell recruitment therapy. This is because the treatment utilizes the bodys own healing process.

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Stem Cell Therapy in Richmond Start Healing Chronic Pain …

Posted: January 1, 2019 at 11:47 am

Stem cell therapy is a targeted treatment that activates your bodys own natural ability to heal and regenerate. With a simple in-office procedure you will improve your quality of life and potentially avoid surgery.

Research continues to show an increasing number of potential benefits from the anti inflammatory, immunomodulatory, and regenerative actions of stem cells. Stem cell therapy treats pain and chronic conditions at their source, returning you to the things you enjoy.

Our stem cell therapy treatment utilizes umbilical cord derived Mesenchymal Stem Cells from FDA regulated cord banks. Mesenchymal Stem Cells are specialized cells that are able to receive signals from the other cells in your body. Stem cells then seek out inflammation and degeneration and go to that location to begin repairing tissue.

Stem cells have been shown to help repair muscle, bone, cartilage and tendons. Research has indicated that stem cells can benefit a wide variety of health complications and may assist in individuals living stronger, healthier lives.

Our mission is simple: Change the lives of our patients by providing an integrative, holistic approach to healing.

We help people suffering from chronic health conditions, chronic pain, autoimmune issues, and many other undiagnosed syndromes and health problems.

We are passionate about caring for our patients who, until now, were not able to find answers and treatments for their underlying health issues.

Regenerative medicine through stem cell therapy is the future of health care and, for our patients, THE FUTURE IS NOW!

Are you a candidate for regenerative stem cell therapy? The answer is YES if you suffer from any of the following:

Were here to help you heal and restore your health today! Please contact us now using the form below to explore how stem cell therapy can help you find relief and embrace your life again!

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Stem Cell Therapy for Knee Injuries and Arthritis

Posted: January 1, 2019 at 11:47 am

Utilizing your own stem cells to help the healing process of injured or degenerated jointsThe human body is made of billions of specialized cells that form specific organs like the brain, skin, muscles, tendons, ligaments, joints, and bone. Each day these cells go through a degenerative and regenerative process. As older cells die, new cells are born from stem cells with the unique capability of being able to create multiple types of other cells. However, when tissues are injured, the degenerative process exceeds this regenerative process, resulting in structures that become weaker, painful and less functional. While there are several types of stem cells, those that are best at promoting musculoskeletal healing (tendon, ligament, cartilage and bone) are found in bone marrow. These mesenchymal stem cells, or MSCs, are essential to successful patient outcomes and at Stem Cell ARTS we utilize the patented Regenexx Stem Cell Protocol, which iscapable of yielding much higher concentrations of these important cells.Most Commonly Treated Knee Conditions and InjuriesBelow is a list of the most common knee injuries and conditions that we treat with stem cells or platelet procedures. This is not an all-inclusive list.Knee Patient Outcome Data

This Regenexx bone marrow derived stem cell treatment outcome data analysis is part of the Regenexx data download of patients who were tracked in the Regenexx advanced patient registry.

Regenexx has published more data on stem cell safety in peer reviewed medical research for orthopedic applications than any other group world-wide. This is a report of 1,591 patients and 1,949 procedures treated with the Regenexx Stem Cell Procedure. Based on our analysis of this treatment registry data, the Regenexx Stem Cell Procedure is about as safe as any typical injection procedure, which is consistent with what we see every day in the clinic.

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These non-surgical stem cell injection procedures happen within a single day and may offer a viable alternative for those who are facing surgery or even joint replacement. Patients are typically able to return to normal activity following the procedure and are able to avoid the painful and lengthy rehabilitation periods that are typically required to help restore strength, mobility and range-of-motion following invasive joint surgeries. Lastly, patients are far less vulnerable to the risks of surgeries, such as infection and blood clots.

Modern techniques in todays medicine allows us to withdraw stem cells from bone marrow, concentrate them through a lab process and then re-inject them precisely into the injured tissues in other areas of the body using advanced imaging guidance. Through Fluoroscopy and MSK Ultrasound, were able to ensure the cells are being introduced into the exact area of need. When the stem cells are re-injected, they enhance the natural repair process of degenerated and injured tendons, ligaments, and arthritic joints Turning the tables on the natural breakdown process that occurs from aging, overuse and injury.

If you are suffering from a joint injury or degenerative condition such as osteoarthritis, you may be a good candidate for a stem cell procedure. Please complete the form below and we will immediately send you an email with additional information and next steps in determining whether youre a candidate for these advanced stem cell procedures.

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Stem Cell Therapy for Knee Injuries and Arthritis

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Transhumanism – Ascension Glossary

Posted: December 31, 2018 at 1:46 am

Transhumanism is an international, cultural and intellectual movement with an eventual goal of fundamentally transforming the human condition, by making available technologies that greatly enhance human intellectual, physical, and psychological capacities. [1]Many transhumanists believe in the compatibility between the human mind and computer hardware, with the implication that human consciousness can be transferred to alternative media, known as mind uploading. Since the Science of the Soul and the Consciousness functions of the spiritual bodies, have not yet been discovered by scientists, this has potentially extremely destructive consequences to human consciousness and the electromagnetic functions of the Lightbody. Posthumans (the result of applied transhumanist technologies) could be completely synthetic artificial intelligences, or a symbiosis of human and artificial intelligence, or uploaded consciousness, or the result of making profound technological augmentations to a biological human.

Transhumanism is a school of thought that seeks to guide us towards a posthuman condition. Essentially, this is about creating artificially intelligent hybrids or cyborgs to replace the organic spiritual consciousness of humans. Some examples are redesigning the human organism using advanced nanotechnology or radical technological enhancements. Some of the proposed biological enhancements are using some combination of technologies such as genetic engineering, psychopharmacology, life extension therapies, neural interfaces, brain mapping, wearable or implanted computers, and entrainment of cognitive techniques. Most of these options are designed to disconnect the human soul from the human body, and prepare the body to be used as a shell for a new host. Effectively, this is integrating technological and pharmaceutical hybridization to damage human DNA, as preparation for body snatching.

The fundamental basis of the Transhumanism concept is the A.I. downloaded into the scientific human mind from the Negative Aliens and Satanic Forces, in their quest to survive and achieve immortality by hijacking human consciousness and ultimately possessing the human host body. They do not have flesh and bone bodies and covet ours. Most academics are filled with a variety of mind control and alien implants to be a cog in the wheel to steadily enforce alien control systems. Most early transhumanism concepts were developed by geneticists interested in eugenics and sustaining life forms in synthetic environments. (Like the eugenic experiments similar to those of the Black Sun Nazis). A common feature of promoting transhumanism is the future vision of creating a new intelligent species, into which humanity will evolve and eventually, either supplement it or supersede it. This distraction on the surface is a scheme, while the underlying motivation is intending species extinction of what we know as humans today. Transhumanism stresses the evolutionary perspective, yet it completely ignores the electromagnetic function of human DNA and the consciousness reality of the multidimensional human soul-spirit. They claim to want to stop human suffering but have no idea of the alien machinery and mind control implants used to imprison human consciousness. They know nothing about the afterlife, what happens during the death of the body or even how the human body or Universe really works, yet they want to control every aspect of the human body with artificial technology.

A primary goal of many transhumanists is to convince the public that embracing radical technology and science is in the human species best interest. With the False God Alien Religions used to spread the rhetoric of fear and mindless obedience on one end, and the primarily atheistic science used to mock all things religious without any comprehension of true spiritual understanding on the other, they have the bases covered. Consciousness and spiritual groups are quickly labeled Conspiracy theorists by scientists to intimidate, discredit and shut us up. Obviously, until people have personal consciousness experiences outside of their body, have the ability to communicate with assorted lifeforms, such as deceased humans and travel to other dimensions, they have zero information about consciousness and are totally uninformed and ignorant about the nature of reality. None of these transhumanist people, are remotely qualified to be put in charge of scientifically directing the future evolution of the human species. Propping up egomaniacs and Psychopaths, and giving them power and control over world affairs and influence over public perception is the game of the NAA Controllers.

The true knowledge of the Sacred Sciences of the Soul and mechanics of human multidimensional consciousness have been obliterated from record and conveniently mind controlled out from the majority of sciences. If scientists integrate theories of the soul or consciousness outside of the consensus of the mind control standard, they risk ridicule and losing their funding and careers. Unfortunately, the controlled mainstream sciences do not recognize multiple dimensions of consciousness inherent in the functions of activated human DNA, or know that biological life and multidimensional human consciousness does not end on this earth. The quest for biological immortality on a prison planet is ludicrous when experiencing the capability of human multidimensional consciousness. After the human body expires, if the undeveloped and disembodied consciousness is merged and assimilated into artificial intelligence, the remnants of that human soul will not have a human body to incarnate into any longer. Hence, that person will lose their connection to organic spiritual biology and cease to be human. Transhumanism is a Consciousness Trap. [2]

Since the persons Consciousness has not been prepared for the afterlife, whatever is left of his energetic quanta will be assimilated into a cyborg body or other types of synthetic life forms or EBEs. There are currently spiritually disconnected humans existing on the earth that will be assimilated into synthetic life forms that appear as Extraterrestrial Biological Entities, but were actually human souls in human bodies in past timelines. Most of the smaller EBE bodies assimilate nutrients from light similar to plants. They are unable to evolve, reproduce, ascend or move into higher dimensions of consciousness. Some of these EBEs have returned to the earth from the future to try to break into the human genetic code, in this earth timeline in order to save themselves. Many of these EBEs were once humans that were involved in the Orion Wars, and were captured in Orion and used in worker colonies. Some from the earth were enslaved on the astral plane by other races of creatures, such as Mantids, Grey Aliens and Reptilians that took them as workers to other planetary systems. Some are even used as minions for carrying out human abductions in MILABS soul transference projects. Many of them had their consciousness erased and they do not remember that they were once human.

This is one of the possible results of the Transhumanism movement underway in this earth timeline now, that leads to the potential future alien or dark force control over that Soul. Once the consciousness is assimilated into artificial intelligence and synthetic biology, that being can no longer incarnate into an organic human form. That person cannot incarnate again into human realms, such as planet earth. They become a displaced entity that cannot die and be reborn into another identity they are enslaved and merged with an AI hive mind. This is desired by many of these negative groups, such as the Alpha Draconis/Orion Group, as then they have full control over the life force of humans that can be made into worker slaves. This is the main purpose as to why Transhumanism is being marketed and pushed aggressively during this time, they want to create more human EBEs and cyborgs or host bodies. When that person drops their body while the Universal Gates are open, they can easily be transported to many different planetary systems for trading as a workforce commodity.[3]

The term directed evolution is used within the transhumanist community to refer to the idea of applying the principles of directed evolution and experimental evolution to the control of human evolution. This has its base in Eugenics theories.

When we look at the larger Galactic picture of consciousness enslavement, we see the NAA's many pronged agenda to target the Brain, CNS and thought forms of every person on earth. Through the agenda of Transhumanism, we see the promotion of hybridization and synthetic integration with artificial neural networks for control over the CNS and Brain. What is starting to surface with more clarity is that our human Neurobiology is wired for empathy, which connects us to higher consciousness and has a spiritual function. The NAA and their minions of soulless AI infected synthetic beings do not have the bio-circuitry for empathy. We are in essence, in a struggle between human EMPATHS, and alien hybridized humans and extra-dimensional aliens that are NON-EMPATHS. [4]

The traumatized are vulnerable to become pawns in further spreading Sexual Misery programing, especially into the younger generation. Transgender ideology is a specific psychological warfare tactic being run by the Controllers, in tandem with Transhumanism, to counter and prevent spiritual Ascension. These satanic agendas are designed to condition people to reject their own bodies, and to generate delusions that can have them mentally identify with anything else but actually being a human and unconditionally loving toward their own natural body.[5]

Mind Controlled Gene Expression

Genetic Engineering

Eugenics

CRISPR

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