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St Austell man with diabetes Chris Witt had leg amputated after blister on toe on Tenerife holiday – Cornwall Live

Posted: May 5, 2017 at 11:42 pm

A St Austell man had to have his leg amputated after a small blister on his toe that developed while he was on holiday in Tenerife turned into a serious infection which wouldn't heal.

Diabetes UK is sharing the story of 63-year-old Chris Witt in an attempt to warn men with diabetes of the importance of foot care.

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Mr Witt has type 2 diabetes and had his leg amputated in late 2016. The guest house owner developed a small blister on his toe after going for a walk in new sandals while on holiday in Tenerife.

This turned into an infection which wouldn't heal, leading first to the amputation of part of his foot and eventually to the loss of his leg below the knee.

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He said: "I didn't realise how dangerous it could be to have an infection and that it can come on so quickly. I wasn't vigilant enough. If you're a man with diabetes you need to check your feet every day and if you see anything wrong get in touch with your surgery. Push for quicker treatment if it's not going fast enough.

"If I'd realised the dangers, I might have saved my leg."

Diabetes UK south west regional head Phaedra Perry said: "Men with diabetes can protect their feet this May by ensuring they attend their annual foot check and that they come away knowing what their risk of developing foot problems is and whether further action is needed.

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"If your feet have not been checked by a healthcare professional in the past 12 months if you've not been invited in for your foot check or you missed your appointment do not put off booking or taking up the offer of a free check. Also, if you spot a problem or have any concerns do not wait for your 12-month check-up make sure you book an appointment as soon as possible as problems can escalate extremely quickly.

"Putting your feet first can prevent the devastating loss of your toes, feet or legs, which will have a huge impact on your life. Everyone with diabetes is entitled to an annual foot check or more frequent checks if you are deemed to be at medium or high risk.

"Checking regularly yourself and having an annual foot check with a health professional can keep you on your feet."

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A spokesman for Diabetes UK said: "Men with diabetes are at a higher risk of chronic foot and leg wounds which can lead to devastating toe, foot or leg amputations, Diabetes UK warns today. Nearly three out of four people who have diabetes-related foot ulcers are men.

"During Foot Health Awareness Month in May, the charity is urging people with diabetes and particularly men with diabetes, to take care of their feet and if they've not had them checked in the past 12 months to not delay in booking in for their free annual foot check with their doctor or nurse.

"Latest figures show there are 20 diabetes-related amputations a day, despite four out of five of these being preventable with good foot care."

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The charity warns that not all people with diabetes are getting the annual foot check they're entitled to on the NHS.

According to the National Diabetes Audit 2015/16, nearly one in six people with type 2 diabetes in Cornwall (16.3%) are missing out on this essential check-up, compared to one in ten across England.

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This rises to more in one in four people with type 1 diabetes in Cornwall (27.6%), in line with the England average.

They said having an amputation has a devastating impact on a person's life through loss of work, immobility and the inability to drive. But if a foot problem is treated quickly it can prevent serious problems in the future.

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Check your feet daily for any signs of redness, breaks in the skin, pain, build-up of hard skin or changes in the shape of your feet. These could be warning signs of early foot problems, so tell your doctor straight away.

Wash and dry your feet every day especially between the toes. Don't soak them in water as this can increase the risk of damage.

Moisturise every day, but not in between the toes (this can make infections more likely).

Check your shoes daily for anything that may rub.

Cut your nails carefully and don't cut down the side of your nails.

Don't use corn removing plasters or blades as these can damage healthy skin.

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The 'touch the toes test' can help you find out if you are losing sensation in your feet. Go to http://www.diabetes.org.uk/feet-care.

Alternatively, you can call the Diabetes UK helpline on 0345 123 2399.

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Fundraiser, program shine light on diabetes – Mountain View Journal

Posted: May 5, 2017 at 11:42 pm

This Saturdays Notorious Nick Memorial Shotgun Match sponsored by the Single Action Shooting Society and the Founders Ranch Shotgun Sports Club will raise funds for the Juvenile Diabetes Research Foundation.

Sign up starts at 8:30 a.m. and shooting begins at 10 a.m. for the event at Founders Ranch at 74 Barton Road. Cost is $50 for 100 target sporting clays, $25 for 50 target 5 stand sporting and $12.50 for 25 target cowboy clays.

The event in its fifth year also brings attention to the causes of juvenile diabetes and diabetes in general, which is a health concern for the area and statewide. According to advocates, more than 12 percent of the states adult population is living with diabetes, which is more than 248,000. Another 615,000 are estimated to have prediabetes, which means their blood sugar levels are higher than normal but not yet high enough to be type 2 diabetes.

Prediabetic is now the new term for people who will likely get diabetes in the future without making changes now to their diet and sedentary lifestyles, said Dr. Linda Stogner, medical director of the Esperanza Family Health Center. Doctors used to call the condition borderline diabetic, but people didnt take the diagnosis serious enough to make significant lifestyle changes.

Brenda Richter, who has been attending a weekly diabetes self-management workshop in Moriarty, said she had been diagnosed as borderline diabetic, which quickly blew up into full diabetes, changing her life. Participants in the workshops held Monday afternoons at Bethel Community Storehouse say the classes have helped them get focused on what they can do to successfully change their lifestyles and diet to better manage the disease.

Danielle Berrien of the Cooperative Extension Service, which sponsored the workshops with the state Department of Health and state Aging and Long Term Services Department, said there is a lot of misunderstanding about the disease, which can lead to kidney failure, blindness, loss of limbs and heart disease. The workshop aims to teach participants about what they can do to better manage the disease by coming up with an action plan with measurable goals to successfully make better food choices and work in more exercising into their daily lives.

You pretty much have to say good bye to processed food, Richter said.

Jennifer White said the workshops have helped her feel less isolated and Effie Zirnheld said the workshops were able to go into more detail than advice given at a doctors office. Participants said it helped that the workshop has Margie Snare as facilitator as she is a person living with diabetes. Berrien said she wants to hold the diabetes workshop twice a year.

Stogner, who has been treating patients in the East Mountains for 30 years, said the disease is one that cuts across all walks of life from mountains residents to flatland farmers. But Stogner said she has patients she has been working with since coming to the area who have been successful in making the necessary lifestyle changes to manage the disease.

I have patients in their 80s who I first saw in their 50s, Stogner said. Im happy to say that none of them have lost their vision, no amputations and no one on dialysis.

Stogner acknowledges that it can be hard for people in rural areas to get good access to unprocessed food. On the exercise side, even taking short walks daily can do a lot to prevent the disease, she said.

Berrien said there are good online resources, such as the websites for the American Diabetes Association, the International Diabetes Center, the Joslin Diabetic Foundation and the National Diabetes Education Program.

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Selig talks diabetes advocacy – Stuttgart Daily Leader

Posted: May 5, 2017 at 11:42 pm

According to Selig, 30 million Americans have diabetes right now and about every 23 seconds someone else is diagnosed with the disease.

Rick Selig, director of the Arkansas Chapter of the American Diabetes Association (ADA), spoke to Stuttgart Lions Club members and guests Wednesday about diabetes and the ways the ADA works to educate the public about it.

According to Selig, 30 million Americans have diabetes right now and about every 23 seconds someone else is diagnosed with the disease.

Thats epidemic proportions, people, and we realize that it affects a lot more than that, that theres people out there that dont even realize that they have it or have what we call pre-diabetes, Selig explained.

The goal of the ADA regarding diabetes is ultimately to find a cure, Selig said, but until then the organization focuses on education, advocacy, research and services to help those living with diabetes.

Selig said the ADA will educate through lunch and learns with different companies and attend health fairs. People can also get information about diabetes through their website at http://www.diabetes.org or by calling (800) 342-2383. According to Selig, the ADA is one of the leading organizations that funds diabetes research, however, several other organizations get involved in funding.

One of the ADAs major services is the diabetes camp for children 8 to 13 years old with diabetes, which is held in Little Rock. He said they have approximately 55 children from around the state who attend the camp each year.

Donations from people like the Lions Club and other organizations is what puts this on, Selig said. It costs us $650 per child to send a kid to camp for one week.

The camp allows children to participate in many fun activities, such as zip lining and canoeing, however, the children are also able to learn about diabetes, including learning how to use pumps and give themselves insulin shots, as well as counting carbs and exercise. Selig said this is sometimes the only time some of the children with diabetes get away from home.

For one week, they get to be just like everybody else, Selig explained. Some of these kids are in rural schools and smaller schools where they may be the only one with diabetes.

When advocating for people with diabetes, Selig said its hard to make everyone happy, but the ADAs goal is to help those with the disease no matter what.

He said recently the Arkansas Legislature passed a law called the Safe At School Law that the ADA advocated for, which allows someone trained in the school, other than the school nurse, to administer insulin to a child in need in an emergency situation. He said this is important, because some school districts have only one school nurse who covers several buildings and may not always be available.

Selig explained that the ADA recently petitioned Congress to look into price gouging for the pharmaceutical companies and medical supply companies in regards to diabetes medications and supplies. He said the investigation is not taking place yet, but they have been assured the issue will be looked into in the future. He explained people across the U.S. often have to make the decision between eating, paying bills and buying insulin or supplies.

Thats a decision nobody should have to make, Selig said.

Another way the ADA is advocating for people with diabetes is showing opposition against the reform of the Affordable Care Act, because if its reformed right now, insurance companies could charge people with pre-existing conditions more for their insurance, according to Selig.

Were standing up for the people with diabetes whether its local or on the national scale, Selig explained.

Selig added, Were actually trying to work ourselves out of a job, because we want to see an end to diabetes.

Lions club member Dave Strauss explained that the club promotes sight and that diabetes is regularly linked to eyesight, stating that eyesight is often one of the things that gets compromised if the disease gets too bad. The club presented Selig with a $1,000 donation to the ADA after his presentation. The Stuttgart Lions Club meets at noon each Wednesday at the Stuttgart Country Club.

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Smart Contact Lens Detects Diabetes and Glaucoma – IEEE Spectrum

Posted: May 5, 2017 at 11:42 pm

While tech giant Google continues to struggle to make a contact lens for monitoring diabetes,researchers at Ulsan National Institute of Science and Technology (UNIST) in South Korea have offered up at least one part of the puzzle: better wearability. Through the use of a hybrid film made from graphene and silver nanowires, the UNIST researchers have made contact lenses for detecting multiple biomarkers that are clear and flexible.

In research described in the journal Nature Communications, the UNIST researchers used graphene-nanowire hybrid films to serve as conducting, transparent, and stretchable electrodes. While the hybrid film alone does not perform any detection, the electrodes do ensure that the electrodes in the contact lenses dont obscure vision and that theyre flexible enough to make wearingthe lenses comfortable.

In addition to offering better transparency and comfort, the contact lenses developed by the UNIST researchers depart from previous contact lens sensors in that theyreable to detect multiple biomarkers. This contact lens should be able to pick up indictorsfor intraocular pressure, diabetes mellitus, and other health conditions, according to the researchers.

To detect intraocular pressure, a dielectric layer is sandwiched between two hybrid films. In this arrangement, the films now become a capacitor that responds to intraocular pressure. At high intraocular pressure, the thickness of the dielectric layer decreases, resulting in the increased capacitance. High intraocular pressure also increases the inductance of the antenna coil by bi-axial lateral expansion.

For detecting glucose, the top hybrid film layeris exposed to tears and detects glucose. In a selected region of the film, the researchers removed the nanowires so only graphene remained. The surface of graphene was then coated with an enzyme that binds selectively to glucose.Thisbinding changes the resistance of the graphene.

The changes of resistance, inductance and capacitance in these two detection modes can be monitored wirelesslyin real-time.

One of the challenging aspects of the research was the glucose sensor, according to the researchers. In tears, there are many interfering ions and molecules that potentially cause false positive responses, explained Chang Young Lee, an assistant professor at UNIST and co-author of the study, in an email interview with IEEE Spectrum. We need to test the selectivity and long-term reliability of the glucose sensor. The effort includes designing and finding a molecule that selectively binds to glucose, which is another large research area.

Lee envisions this research as a novel platform that will enableintegration of glucose sensor onto a soft contact lens. Measuring the glucose accurately and reliably is another large research area, Lee added. A good glucose sensor developed by another researcher, for example, can easily be integrated onto our platform.

In this novel platform, both the graphene and the silver nanowires contribute indispensible properties. The silver nanowires offer a one-dimensional (1D) conducting material, and by creating a network (mesh) of it, its possible to make a transparent, conducting, and flexible film. However, the film made of silver nanowires alone has limitations, such as high contact resistance at the nanowire-nanowire junctions, low breakdown voltages, poor adhesion to flexible substrates, and oxidation in harsh environments.

This is where the two-dimensional (2D) graphene comes in, with its properties of being highly transparent, conducting and flexible. By creating a hybrid structure of graphene and nanowires, the limitations of the nanowires are overcome. The key is in the hybrid of 1D and 2D structures, added Lee.

IEEE Spectrums nanotechnology blog, featuring news and analysis about the development, applications, and future of science and technology at the nanoscale.

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Technique opens up potential of tailoring material properties nearly atom-by-atom 2May

Discovery could be the answer to the demands for increasing information storage density as device feature sizes decrease 26Apr

Technique could reduce costs for compound semiconductor circuits and lead to new devices 24Apr

The new molybdenum disulfide microprocessor has 115 transistors 11Apr

A graphene photodetector can pinpoint the position of light that falls far from it 10Apr

Researchers at SLAC are leveraging X-rays to enable the next generation of batteries and photovoltaics 5Apr

Diamondoids are showing promise in applications as divergent as electron guns and quantum computing 31Mar

The electronic skin is touch-sensitive and could be inexpensively manufactured 30Mar

Stanford researchers are getting a lot of mileage from nanomaterials by analyzing market needs 29Mar

The elliptical shape makes the lasing process easier 20Mar

Japanese materials company prototypes a 26.3 percent efficient silicon cell, steps away from the 29 percent theoretical maximum 20Mar

Otherlabs self-fluffing fabric changes its insulation in response to temperature 18Mar

Development is incremental in molecular nanotechnology, but it is coming along slowly 14Mar

New encoding method makes it possible to come close to the theoretical maximum for DNA data storage 2Mar

Replacing high-voltage power source with nanogenerators increases sensitivity to new records 27Feb

First borophene-based heterostructure should guide future work with borophene in nanoelectronic applications 23Feb

Five teams, four rockets, and 380,000 kilometers togo 22Feb

Current can literally blow copper interconnects away, but graphene could keep them intact 17Feb

Biocompatibile inks open up medical devices for inkjet-printed devices 2Feb

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Bob Marley’s nephew to launch reality TV show on diabetes – KING5.com

Posted: May 5, 2017 at 11:42 pm

KING 7:00 AM. PDT May 05, 2017

Bob Marley's nephew, Charles Mattocks, is launching a reality show on Discovery.

Just like his uncle, Bob Marley, Charles Mattocks is on a mission to motivate, inspire and educate people but this time with diabetes.

After being diagnosed with Type 2 diabetes eight years ago, Mattocks was forced to be his own advocate. His doctor prescribed medication but didn't specify a plan to help him control the disease.

"He didn't give me any information as far as what to look for, follow up with, what to eat, what to do next. He just gave me medication," explained Mattocks.

The celebrity chef turned TV producer lost weight, is now off medication and his diabetes is under control. But he knows there are many people living with diabetes who are still struggling with their health because of a lack of education.

That's why he became passionate about leading the fight against diabetes and wrote a cookbook and produced a documentary.

Now, he's about to launch the first ever diabetes reality TV show called "Reversed" on Discovery Life Channel.

"I thought if we brought people in a house, and bring in all the experts that they would need to see over a year's time, like endocrinologists, nutritionists, dieticians, and bring them in one house and be able to inspire them and also educate them, what would we have?" Mattocks said.

Mattocks brought five contestants into one house in Jamaica to help them reverse their unhealthy habits.

After spending time with experts, they went home and began making changes.

Mattocks lights up when he talks about the life-changing results for two of the contestants, including one named Margie.

"When I first met her, she said she didn't like green leafy vegetables. She said she was allergic to green leafy vegetables," said Mattocks. "Now she's sending me pictures of her eating salads and green leafy vegetables and juicing and exercising."

Mattocks hopes the show reaches thousands of people and inspires them to make changes in their own lives.

" When I think of what we really did, and I think of where they might have been over the next couple of years, it moves me," said Mattocks.

"Reversed" airs in July on the Discovery Life Channel.

2017 KING-TV

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Popular TED Talks explore future of agricultural innovation, biotechnology – Genetic Literacy Project

Posted: May 4, 2017 at 3:42 pm

The well-known TED Talks is a clearinghouse of big thinkers and big ideas, and quite a few of them have focused on agriculture and food production over the years.

Engineering Drought Resistance Jill Farrant, a Professor of molecular and cell biology at University of Cape Town, South Africa, is studying how ancient DNA can be turned on to help important food crops fight off drought. She and colleagues have been studying resurrection plants to achieve this goal. Resurrection plants are those that can undergo extreme drought without water for months or even years. Then when the next rain comes along within 12 to 48 hours the plants green up and start growing again.

Farrants How We Can Make Plants Survive Without Water TED Talk featured her research into how resurrection plants work and if those special characteristics could be transferred into other plants, especially food crops.

Robot Swarms Vijay Kumar, Dean of the University of Pennsylvanias School of Engineering and Applied Science, wowed his TED Talk audience with his presentation titled The Future of Flying Robots. His lab is developing autonomous flying robots that use onboard sensors, cameras, and laser scanners to map the environment it is in and avoid obstacles while navigating.

All agriculture-related TED Talks can be found at ted.com/topics/agriculture.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post:TED Talks Take on Agriculture Innovation

For more background on the Genetic Literacy Project, read GLP on Wikipedia

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Plandai Biotechnology Expanding Footprint of Phytofare into U.S. with Continued Sales – Yahoo Finance

Posted: May 4, 2017 at 3:42 pm

NEW YORK, NY--(Marketwired - May 04, 2017) - Planda Biotechnology (PLPL) announced last week that its highly bioavailable Phytofare Catechin Complex would be the active ingredient in Capital Brand's reformulated and soon-to-be released SuperFood Fat Burning Boost, which is used with the well-known brand NutriBullet. This week we learned that thanks to a deal with Coyne Healthcare -- Planda's signature brand Phytofare will make its way to the U.S. and Europe as the star ingredient in Coyne Healthcare's product Origine 8.

Coyne Healthcare placed an order for 1.2 million of Planda's Origine 8 capsules, which is a product that not only uses the highly bioavailable green tea extract, Phytofare Catechin Complex, but further enhances the bioavailability of the extract by using an advanced liposome technology developed and clinically validated to improve the delivery of nutritional substances.

Origine 8 is a product that entraps all 8 of the catechins of the tea plant, and according to Planda, it is the only catechin-based capsule on the market backed by human clinical studies that prove it has superior bioavailability.

Coyne Healthcare has already been selling Planda's unique product in South Africa, but it now expects to launch Origine 8 this month in both the U.S. and Europe. The good news for Planda is that Coyne Healthcare has forecasted sales of 10.6 million Origine 8 capsules in 2017, and Coyne expects sales to further increase to 24 million Origine 8 capsules in 2018.

Coyne makes its products (http://coynehealthcare.co.za/#products) available through pharmacies, health food stores and medical practitioners, so for both NutriBullet and Coyne Healthcare to bring Planda's signature brand to the U.S., investors will have a great opportunity to physically see their investment up close and personal.

Sales at Planda and the recognition that the company is gaining globally, is clearly a response to the efforts made by the new COO, Callum Cottrell-Duffield, well before now. He led the company's sales and marketing team in its effort to grow the brand and expand the company's footprint worldwide after Planda's signature product was available for mass production and ready to market on a much broader scale last year. His work to increase sales and marketing throughout Africa, the United States, Europe, Asia and South America by telling the Planda story, is starting to pay off now in 2017.

And, with brands like NutriBullet and Coyne Healthcare, who both use and market only the highest quality ingredients in their products, advertising the Phytofare name, it shouldn't take long for Planda to grow quite an impressive sales footprint worldwide.

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We are not a registered broker, dealer, analyst, or adviser. We hold no investment licenses and may not sell, offer to sell or offer to buy any security. Our publications are not a recommendation to buy or sell a security.

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Section 17(b) of the 1933 Securities and Exchange Act requires publishers who distribute information about publicly traded securities for compensation, to disclose who paid them, the amount, and the type of payment. In order to be in full compliance with the Securities Act of 1933, Section 17(b), we are disclosing that SMMG is compensated $5,000 per month by Plandai Biotechnology for content development. Neither SMMG nor anyone associated with it owns shares in PLPL.

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Puma Biotechnology, Inc. (PBYI) held by 19 SEC 13F Filers | Post … – Post Analyst

Posted: May 4, 2017 at 3:42 pm


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Potential predictor of glaucoma damage identified – Washington University School of Medicine in St. Louis

Posted: May 4, 2017 at 3:42 pm

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Research in mice and patients suggests biomarker could predict vision loss

At the center of the image is an optic nerve with glaucoma damage, signified by loss of color and a round rim of pink tissue within the nerve. Researchers at Washington University School of Medicine in St. Louis have identified a biomarker that appears linked to damage to cells in the retina of the eye. The marker may make it possible to better monitor the progression of glaucoma, as well as the effectiveness of treatment for the blinding disease.

Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, theres no way to accurately predict which patients might lose vision most rapidly.

Now, studying mice, rats and fluid removed from the eyes of patients with glaucoma, researchers at Washington University School of Medicine in St. Louis have identified a marker of damage to cells in the eye that potentially could be used to monitor progression of the disease and the effectiveness of treatment.

The findings are published online May 4 in the journal JCI Insight.

There hasnt been a reliable way to predict which patients with glaucoma have a high risk of rapid vision loss, said principal investigator Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences. But weve identified a biomarker that seems to correlate with disease severity in patients, and what that marker is measuring is stress to the cells rather than cell death. Other glaucoma tests are measuring cell death, which is not reversible, but if we can identify when cells are under stress, then theres the potential to save those cells to preserve vision.

Glaucoma is the second-leading cause of blindness in the world, affecting more than 60 million people. The disease often begins silently, with peripheral vision loss that occurs so gradually that it can go unnoticed. Over time, central vision becomes affected, which can mean substantial damage already has occurred before any aggressive therapy begins.

Manypatients start receiving treatment when their doctors discover they have elevated pressure in the eye. Those treatments, such as eye drops, are aimed at lowering pressure in the eye, but such therapies may not always protect ganglion cells in the retina, which are the cells destroyed in glaucoma, leading to vision loss.

Apte, also a professor of developmental biology, of medicine and of neuroscience, said that all current treatments for glaucoma are aimed at lowering pressure in the eye to reduce ganglion cell loss and not necessarily at directly preserving ganglion cells.

Glaucoma specialists attempt to track the vision loss caused by ganglion cell death with visual field testing. Thats when a patient pushes a button when they see a blinking light. As vision is lost, patients see fewer lights blinking in the periphery of the visual field, but such testing is not always completely reliable, according to the papers first author, Norimitsu Ban, MD, an ophthalmologist and a postdoctoral research associate in Aptes laboratory.

Some older people dont do as well on the visual field test for reasons that may not be related to whats going on in their eyes, Ban explained. He said that finding a marker of cell damage in the eye would be a much more reliable way to track the progression of glaucoma.

We were lucky to be able to identify a gene and are very excited that the same gene seems to be a marker of stress to ganglion cells in the retinas of mice, rats and humans, Ban said.

Studying mouse models of glaucoma, Ban, Apte and their colleagues identified a molecule in the eye called growth differentiation factor 15 (GDF15), noting that the levels of the molecule increased as the animals aged and developed optic nerve damage.

When they repeated the experiments in rats, they replicated their results. Further, in patients undergoing eye surgery to treat glaucoma, cataracts and other issues, the researchers found that those with glaucoma also had elevated GDF15 in the fluid of their eyes.

That was exciting because comparing the fluid from patients without glaucoma to those with glaucoma, the GDF15 biomarker was significantly elevated in the glaucoma patients, Apte said. We also found that higher levels of the molecule were associated with worse functional outcomes, so this biomarker seems to correlate with disease severity.

Apte and Ban dont believe that the molecule causes cells in the retina to die; rather, that it is a marker of stress in retinal cells.

It seems to be a harbinger of future cell death rather than a molecule thats actually damaging the cells, Apte said.

A potential limitation of this study is that the fluid samples were taken from the eyes of patients only once, so it was not possible to monitor levels of GDF15 over time. In future studies, it will be important to measure the biomarker at several time points to determine whether levels of the biomarker increase as the disease progresses, Apte said.

He also would like to learn whether GDF15 levels eventually decline in those who have significant vision loss from glaucoma. In theory, Apte said, when most of the ganglion cells in the retina already have died, fewer cells would be under stress, and that could mean lower levels.

So we are interested in doing a prospective study and sampling fluid from the eye over several months or years to correlate glaucoma progression with levels of this marker, he said. Wed also like to learn whether levels of GDF15 change after treatment, a particularly important question as we try to develop therapies that preserve vision more effectively in these patients.

Ban N, Siegfried CJ, Lin JB, Shiu YB, Sein J, Pita-Thomas W, Sene A, Santeford A, Gordon M, Lamb R, Dong Z, Kelly SC, Cavalli V, Yoshino J, Apte RS. GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients. JCI Insight. May 4, 2017.

This work was supported by the National Eye Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke and the National Institute of General Medical Sciences, of the National Institutes of Health (NIH), grant numbers R01 EY019287, UL1 KL2TR000450, P30 DK56341, P30 DK02057, DK104995, R01 EY021515, R01 DE0220000, R01 NS0824446, P30 EY02687, T32 GM007200, UL1 TR000448 and TL1 TR000449. Additional funding provided by the Schulak Family Gift Fund for Retinal Research, the Jeffrey Fort Innovation Fund, the Kuzma Family Gift Fund, the Central Society for Clinical and Translational Research, a Research to Prevent Blindness Physician Scientist Award, the Washington University Institute of Clinical and Translational Sciences, the American Federation for Aging Research, the Vitreoretinal Surgery Foundation and an unrestricted grant from Research to Prevent Blindness Inc.

Washington Universitys Office of Technology Management has filed intellectual property applications based on these studies in which the authors Rajendra S. Apte and Jun Yoshino are listed as inventors.

Washington University School of Medicines 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is one of the leading medical research, teaching and patient-care institutions in the nation, currently ranked seventh in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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Potential predictor of glaucoma damage identified - Washington University School of Medicine in St. Louis

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Diabetes Health | Investigate.Inform. Inspire

Posted: May 4, 2017 at 3:41 pm

Its not the everyday worries that normal people stress about. Diabetes makes you worry about it every day, all day. My husband is quick to ask Can you change what youre worrying about? and when I confirm that I cant,

DAs of 2016, the United States has one of the lowest labor-participation rates among prime working-aged men living in developed countries, trailing only Italy. About 89% of men aged 25-54 are currently working or looking for work, compared to over

For a former college athlete, Ephraim Smiley doesnt really care for exercise.

The 6-foot-3 defensive end loved playing football for Butler University in the 1970s, enough so that he tried out for the Canadian Football League. But he didnt

Dear Nadia:

I am a type 2 who was diagnosed 10 years ago. I have a lot of urinary tract infections and they are painful. Any advice on why this keeps happening?

Margaret

Dear Margaret:

One of the most dramatic

I had the opportunity, recently, to be in Washington DC. I love Washington DC and it is one of the most exciting places on earth. So much happens there and whether you love or hate whoever is in office does

This crosswordpuzzle was inspired by this weeks news and podcast reports. Play along with us to test your knowledge and comprehension on topics we post Monday-Friday.

Please click the link below to download this weeks Diabetes Health CrosswordPuzzle

This crosswordpuzzle was inspired by this weeks news and podcast reports. Play along with us to test your knowledge and comprehension on topics we post Monday-Friday.

Please click the link below to download this weeks Diabetes

With so much going on, you may have missed the latest in diabetes news this week. Not to worry! Weve got you covered with the Diabetes Health Weekly Roundup to share the latest news, podcasts and stories from this week.

Current American Diabetes Association guidelines recommend that youth with diabetes receive diabetic retinopathy screenings. Type 2 diabetes patients should receive their screening at the time of their initial diagnosis, while type 1 patients should receive their screening within 3-5 years.

I once had an Endo tell me that with syringes, I would probably not be able to get my A1C down much lower than the 7 that I had long been hovering at. He also lived with Type 1 diabetes

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Diabetes Health | Investigate.Inform. Inspire

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