by: Marty Toohey, American-Statesman Staff Updated: Apr 24, 2017 - 9:52 PM

SAN ANTONIO, Tx. - Years of testing remain, but UT Health San Antonio researchers say theyve cured Type 1 diabetes in mice.

In peer-reviewed paper, they say a gene transfer can wake up cells in the pancreas to produce insulin.

>> Read more trending news

Health researchers at the University of Texas think they have found a way to trick the body into curing Type 1 diabetes.

The immune system of a person with diabetes kills off useful beta cells, but the UT researchers say they have found a way to make other cells in the pancreas perform the necessary work. Their approach, announced earlier this month in the academic journalCurrent Pharmaceutical Biotechnology, not only would have implications for Type 1, formerly called juvenile diabetes, but also could help treat the far more common Type 2 variety, also known as adult-onset diabetes.

The researchers have cured mice, which are genetically similar to people but different enough that new rounds of animal testing and millions of dollars more are needed before human trials can begin. The researchers approach is sure to garner skeptics, at least in part because it is a significant departure from the many other attempts at curing diabetes, which typically involve transplanting new cells and/or suppressing the immune systems attempts to kill off useful ones.

By contrast, were taking a cell that is already present in the body its there, and its happy and programming it to secrete insulin, without changing it otherwise, said Ralph DeFronzo, chief of the diabetes research at the UT Health Science Center at San Antonio.

Diabetes is a disease characterized by a persons inability to process carbohydrates, a condition that if untreated can lead to often-catastrophic health consequences: lethargy, diminished eyesight, heart attacks, strokes, blindness and a loss of circulation in the feet that could lead to amputation. The Centers for Disease Control and Preventionestimate that in 2014, about 29 million Americans almost 1 in 10 had diabetes.

The core problem is insulin. Most people naturally secrete that substance when they eat something with carbohydrates, such as bread, potatoes and candy bars. Insulin acts like a concierge that escorts the sugar from the bloodstream into the cells, providing the cells with the energy to function. In most people, the body is continually monitoring blood sugar and producing insulin as needed.

In Type 2 diabetes which makes up 9 out of 10 diabetes cases and is generally associated with older people and weight gain the cells reject the insulin, causing sugar to build up in the bloodstream even as cells are starved for energy. Type 2 is often treated with pills that tell the cells to let in the insulin. But in Type 2 diabetes, the body also often gradually loses the ability to produce insulin, requiring insulin injections.

In Type 1 the type the researchers studied the body has simply stopped producing insulin. This type often manifests in children, though it can sometimes develop in adults as well.

The reason the body stops producing insulin is that it kills off the pancreas beta cells, which produce insulin. People with Type 1 diabetes must get their insulin from injections or ingestion, a cumbersome and often imprecise task. Too little insulin and blood sugar levels stay high for extended periods, potentially damaging the body; too much and blood sugar levels crash, possibly causing a person with diabetes to faint or experience an even worse problems, such as a stroke.

DeFronzos partner, Bruno Doiron, decided to see whether the body could reliably produce insulin without transplanting new cells. He used a gene transfer technique on mice, delivered via a virus, that activated insulin production in cells already in the pancreas for instance, those that produced certain enzymes.

Were not fundamentally changing the cell, DeFronzo said. Were just giving it one additional task.

The mice immune systems did not attack the new insulin-producing cells. Most important, according to the findings: The cells produced the right amount of insulin: not so much that they sent a mouse into a blood sugar free fall, not so little that blood sugar levels stayed high. The mice have shown no sign of diabetes for more than a year, according to the findings.

Quite a bit of work remains before testing will start on people. If they can raise enough money they estimate $5 million to $10 million they can proceed to testing on larger animals, such as pigs, dogs or primates, a next step that would be planned in conjunction with the U.S. Food and Drug Administration.

They hope to start human trials in three years.

DeFronzo and Doiron said they expect skepticism but said much of it will be driven by how unconventional their work is. Doiron added that, although the technique is unconventional in the context of diabetes, using a virus to deliver a gene transfer is an established technique, having been approved dozens of times by the FDA to treat diseases.

We can use the cells the body has naturally, Doiron said. This will simply wake up the cells to produce insulin.

Type 1 and Type 2 diabetes

The work of Bruno Doiron and Ralph DeFronzo focuses on Type 1 diabetes, not Type 2.

Both diseases involve a problem with insulin, the substance that healthy bodies produce to take sugar from the bloodstream into the cells and power the body.

Type 2 is far more common. The main issue is that the cells reject insulin, causing sugar to build up in the bloodstream. The common treatment is a pill that makes the cells accept the insulin (and sugar it carries into the cell). But over time, people with Type 2 diabetes often lose the ability to produce insulin.

With Type 1 diabetes, people simply stop producing insulin. Their bodies kill off the cells in the pancreas that produce it.

Those with Type 1 diabetes must inject or ingest insulin. People with Type 2 often grow increasingly dependent on insulin injections, though Type 2 can sometimes be cured or controlled through diet and exercise.

2017 Cox Media Group.

The rest is here:
Scientists in Texas closer to diabetes cure with unconventional treatment - icFlorida

TRAVERSE CITY His father had it. His maternal grandfather had it. So Ross Sussman assumed his Type 2 diabetes day of reckoning would come.

"It was just a question of when," said Sussman, 83.

But prepping for the diagnosis does not make living with it any easier, Sussman said, after "when" became official 20 years ago.

"Like many people, I enjoy sweets. I had to cut way back, and I lost weight in maybe the first couple years, but then it kind of stopped," Sussman said.

It took a toll on his wife, Evy, too. She tried not to police her husband's eating habits, but cherished social routines like post-movie-or-concert dining changed unpleasantly, she said.

"Socially, it just felt funny when you're ordering a salad when everybody else ordered strawberry pie," said Evy, 75.

But Ross' diabetes class last summer empowered them both, they said, as it combined clinical, group and follow-up approaches to positive behavior.

"It really encouraged me in the way that nobody else can make me do what I'm supposed to screw up my mind or unscrew it to do," Ross said. "It's different from making promises to myself, where I'd probably keep half of them."

The couple lives part time in Minneapolis, Minnesota, and part time in Northport, where the Area Agency on Aging of Northwest Michigan offered a pilot version of LIFE with Diabetes last summer.

The agency will offer the program to Grand Traverse area diabetics over 50 this spring.

The program kicks off with a consultation with a nurse diabetes educator and registered dietitian, and spouses and caretakers are encouraged to attend.

"I liked being included, " Evy said. "As many conditions are, it's a family issue."

The program continues with six weekly group sessions, then wraps up with a three-month post-program follow-up session.

It's geared to promote self management and encouragement for those who need it, said Darcia Brewer, AAANM's registered dietitian and program manager.

"Once you're diagnosed, you get the initial education session. But life changes, conditions change and we face so much more than diabetes," Brewer said. "No one ever can be perfect 100 percent of the time. Even people who know all the information get busy with life, and lax with what we're doing at different stages of the process."

Munson Healthcare's Community Dashboard shows almost a quarter of the 5-county area's Medicare population (over 65) has diabetes a trend that shows no signs of slowing, Brewer said.

"Statistically, with increases in obesity and the number of diabetics who go undiagnosed, it's unfortunate, but that will continue to grow," Brewer said.

They hope to offer the program in low-income housing and apply to Medicare for future funding, she said. The agency currently is offering initial consultations May 8-10 with group sessions May 23 to June 27 from 10 a.m. to 12:30 p.m. at the Area Agency on Aging of Northwest Michigan, at no cost.

Ross compared living with Type 2 to living on a stagecoach.

"It's moving, and some people are driving, some are running behind it, and others are just being pulled along," Ross said.

For more information or to register please call 1-800-442-1713 by April 28.

Session dates/times: Individual consultations will be offered May 8-10. Group sessions on Tuesdays, May 23 to June 27 from 10 a.m. to 12:30 p.m., at the Area Agency on Aging of Northwest Michigan, 1609 Park Drive.

Requirements: 50 or older who have Type 2 diabetes (and family caregivers) living in the greater Grand Traverse region. Registration is required by April 28.

Cost: No cost to attend but need a primary care physician referral.

View original post here:
Diabetes program combines clinical, group and caregiver approach ... - Traverse City Record Eagle

Four times as many deaths may be caused by diabetes, according to a recent study by Boston University School of Public Health published in the online journal PLOS One.

The study argued that diabetes caused 12 percent of deaths in the U.S. Currently, death certificates indicate that 3.3 percent of deaths in the U.S. are caused by diabetes. If the studys findings prove to be accurate, diabetes would become the third-leading cause of death in the United States, up from the seventh.

According to the Kentucky Behavioral Risk Factor Surveillance Survey, diagnosed diabetes among adults nearly doubled in Kentucky from 6.5 percent to 12.5 percent from 2000 to 2014. Now, one in eight Kentucky adults, or 424,670 people in Kentucky are estimated to have diagnosed diabetes.

In 2015, the rate of diabetes increased again to 13.4 percent. Nationally, nearly 10 percent of people have diabetes.

The Centers for Disease Control estimates 138,000 Kentuckians are living with undiagnosed diabetes.

The Pennyrile region of Kentucky has a comparatively average rate of diabetes, at 12.1 percent. Regions along the eastern part of Kentucky have rates as high as 17.8 percent.

It was surprising to me that they would put it at 3 percent, said Christian County Health Department Nurse Jennifer Boone. Diabetes is just so hard on the entire body. It effects the entire body. All the organ systems, everything.

Diabetes is a group of diseases in which high levels of blood sugar are found in the body for extended periods of time.

Type 1 Diabetes comes from the pancreas failing to produce enough insulin. Type 2 Diabetes is usually caused by obesity and inactivity, when the body does not respond to insulin properly. Type 2 Diabetes usually occurs in later stages in life and is considered a result of lifestyle choices.

Its a lifelong thing. A lot of people think that if they eat healthy, if they exercise, if they are able to come off their medication then they dont have diabetes, Boone said. Its not like its ever really cured. Its just managed well.

Diabetes can cause kidney failure. It can also cause blindness, as the blood vessels in the eye can become damaged by the high amount of blood sugar caused by diabetes.

Gums can also become infected and inflamed by diabetes.

Any open wounds take longer to heal with diabetes, leading to many festering sores for those who suffer from the disease.

Kentucky has the 12th highest mortality rate in America. Exercise and a good diet are considered to be good forms of diabetes prevention.

People with higher than average blood sugar levels are considered to have prediabetes. Those with that condition can prevent diabetes with exercise and a good diet.

The Christian County Health Department advocated for the expansion of the Hopkinsville Greenway System during the debate over H-CC WINS, because the organization believed that the system would promote walking in the community, which would lead to better health.

Read more:
Diabetes may cause more deaths than previously thought - The Messenger (subscription)

By Dr. Allan Frankel, M.D. Greenbridge Medical

March 28, 2017 On Diabetes AlertDay it is fitting to discuss not only attempts at managing the disease, but also contributing factors and other conditions related to the disease.

For some time I have been recommending whole plant cannabis CBD for patients with Diabetes. We have seen a substantial lowering of their glucose levels in those with Type II Diabetes including several patients Hemoglobin A1C levels normalize so they are able to stop their Type II Diabetes medications.

The first time I saw this with a Diabetic, he called me after having some hypoglycemic episodes while taking CBD in addition to his Metformin. I told him to stop his Metformin and continue his CBD. His glucose levels normalized and he remained off Metformin. This is a good demonstration of blood sugar control over a three-month period. With any patient with Type II Diabetes, I warn them about this.

With regard to cholesterol, Diabetes can raise bad cholesterol levels and lower good cholesterol levels. Once a patients blood sugar levels are stable, if they are on a statin I will often discuss with the patient and their primary care doc, the idea of stopping the statin and monitoring their cholesterol levels. The drop in cholesterol is not overnight. It can take some months for reasons we dont yet understand. However, we are seeing improvements in cholesterol levels and many patients remain off their statins.

We have also seen improvements ranging from apparent stabilization of macular degeneration and help with neuropathic pain. Sometimes combined with THC, CBD is a vascular and renal protectant.

Finally with regard to weight and Diabetes, there is certainly a connection to being overweight and the onset of Diabetes. I have written about the effect of CBD on curbing appetite before. The ability to achieve weight loss with CBD is real.

So, when discussing CBD and Diabetes, it is a multi-pronged approach. Helping patients with weight, cholesterol and glucose issues. I believe this is all happening on a number of metabolic levels, such as bringingthe sensitivity of insulin back to normal.

So, help with many major issues resulting from, and associated with diabetes can be achieved with CBD. For certain, it is worth a try.

2017 Greenbridge Medical. All rights reserved. Posted by special permission. Original article appeared here.

Read more here:
Diabetes-More Than Blood Sugar - Oregon Cannabis Connection

Crain's Detroit Business

Michigan tests 'pay- for-success' model for diabetes prevention Crain's Detroit Business The model is set to get another early test drive in Michigan, expanding a proven diabetes prevention program offered by the National Kidney Foundation of Michigan in six Metro Detroit and West Michigan counties. For nonprofits, the model promises a new ...

Follow this link:
Michigan tests 'pay- for-success' model for diabetes prevention - Crain's Detroit Business

According to researchers, the results of their study illustrate the importance of intestinal bacteria's contribution to the operation of diet, metabolism and health interface.

Results were published in Scientific Reports magazine. The study was conducted at the University of Eastern Finland LC-MS-metabolomiikkakeskuksessa. The partners had a large number of Finnish and Swedish experts.

The study compared two groups who took part in a wider Diabetes Prevention study (DPS). Everyone had at the beginning of the study excess weight and impaired glucose tolerance. During 15 years of follow-up part of the ill with type 2 diabetes, some not. Differences between these two groups studied the unallocated metabolomics analysis. It can be studied to determine the metabolic profile of a concentration of a large number of metabolites rather than examining only a few of the predetermined marker.

The main differences with type 2 diabetes affected and unaffected metabolism profiles was observed at concentrations of the indole propionic acids and certain lipid metabolism products.

High serum concentration of the indole propionic acids were protected with diabetes illness. Indole propionic acids are intestinal bacteria metabolite. A generous use of whole grains, dietary fiber boosted its content. Indolipropionohapon a greater amount of the pancreatic beta-cell insulin secretion appeared to remain preferred, which may explain the protective effect.

Indole propionic contacting the risk of diabetes explained DPS material in addition to the two population-based study file, the file METSIM Finnish and Swedish VIP material. Also, there it turned out to be diabetes protective factor.

The study identified several new lipid metabolism products, with a high concentration was associated with improved insulin sensitivity and reduced the risk of diabetes. These metabolites content of the higher, the less of saturated fat diet. They, as well as the indole propionic acids, showed a high concentration of the protective body in low-grade inflammation of the farm.

- intestinal bacteria have been found in other studies to affect the risk of developing excess weight. In light of these results, the indole propionic acids may be one factor that mediates diet and intestinal bacteria a protective effect, academy researcher Kati Hanhineva says.

Direct determination of intestinal bacteria is difficult, so produced by the metabolism of intestinal bacteria intermediates assay may be useful in methods to examine the role of intestinal bacteria such as diabetes pathogenesis.

The DPS is the first randomized controlled lifestyle intervention study, which demonstrated that type 2 diabetes is preventable lifestyle changes in subjects with impaired glucose tolerance. Major lifestyle changes were weight loss, increased physical activity and a change in diet more in line with the recommendations of, for example, whole grain cereals, fruit and vegetables with respect to the use.

This article has been republished frommaterialsprovided byUniversity of Eastern Finland. Note: material may have been edited for length and content. For further information, please contact the cited source.

Reference

de Mello, V. D., Paananen, J., Lindstrm, J., Lankinen, M. A., Shi, L., Kuusisto, J., ... & Bergdahl, I. A. (2017). Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Scientific Reports, 7.

Visit link:
Gut Bacteria Offers Protection from Type 2 Diabetes - Technology Networks

I wish I could say I was a friend of Mary Tyler Moores, she surely made you feel that way. There was a time when she, or her beloved husband Robert, and I would pass and a hello was stated. We knew of each other in the same battle. Shewrote a wonderful inscriptionin her book when she sent it to me to thank me on a specific project we worked on together and I will cherish it forever.

She THANKED me. Really? Like I could ever be on par with what she had done over the years. We worked together on fundraising, Washington DC advocating, and when it came to ANYTHING diabetes..rest assured Mary was there in full forcehow lucky was I to have just a little piece of life with this incredible woman.

Its not often one gets to work with an icon, with a person who has her character-genetic pool somewhere in almost every comedic character to appear on TVshe was not the bestshe was thebest of the best and she did it-while battling diabetes.

I have stated it before, and will always feel the same, no one in the celebrity world came close to do for the world of diabetes than what Mary Tyler Moore accomplished with JDRF. Her efforts were tireless over the years. She would attend events, meet with elected officials, testify before congress and yet, it was when she met those who lived like her.with diabetes, that I will remember most. The time she took to speak to them and relate to them, to tell them they would be okay..that is theMary I will remember most.

Every organization under the sun wishes they had a spokesperson the caliber of Mary Tyler Moore. Her connection with JDRF (and what was then JDF) was, and is, legendary. She loved the JDRF and thepeople involved with the organization. How fortunate they are, and were, to have Mary as part of their family. My heart goes out to the manywho worked with her at theJDRF, especially Karen Brownlee, who worked with Mary foryears as the Liaison between theJDRF and Marys people.

Mary had but one goal when it came to diabetes.to bring to the attention of the world the battle of diabetes and how important it is to one day cure it. How important it is to handle it. Perhaps if she meant something to you, you can give a donation to JDRF in her memory. Mary would want it done that way. I did. Its the least I could do for the woman who taught me to fight diabetes with as much fierceness as possible and at the same time; tryto turn the world on with a smile..which no one did better than Mary Tyler Moore

Rest in Peace friend, and thank you. Iam a DiabetesDad.

See original here:
Diabetes Dad: No One was Better for Diabetes Causes than Mary.RIP - Diabetes Health (press release)

Dr. Gabe Mirkin

Recent studies show that the high blood sugar of diabetes is caused by excess fat in: the liver (JAMA, February 14, 2017), the muscles (J Cardiovascular Pharmacology and Therapeutics, April 2017) and the pancreas ((Diabetes Care, December 2015). Diabetes can be treated and often cured with: exercise that removes fat from muscles (Scandinavian Journal of Medicine & Science in Sports, March 13, 2017;27(5)) and diets that remove fat from the liver and other organs (Diabetologia, 2011 Oct; 54(10): 25062514).

The Studies A study from Finland shows that high-intensity interval training rapidly lowers blood sugar levels and increases a Type II diabetics cell response to insulin (Scan J Med & Sci in Sprts, March 13, 2017;27(5)). Both healthy and diabetic patients, 40-50 years old, performed either continuous exercise or 4-6 repetitions of 30 seconds of all-out cycling with four- minute recoveries between each interval, three times a week for two weeks. At the end of just six workouts in two weeks, the thigh muscles of diabetics were able to remove the same amount of sugar from the bloodstream as the thigh muscles of non-diabetics. This means that the muscles of diabetics were able to clear sugar from the bloodstream in a normal manner.

In another study, researchers at the Mayo Clinic showed that both weightlifting and cycling reversed some of the effects of aging on muscles (Cell Metabolism, March 2017;25(3):581592). Both types of exercise increased: endurance, fitness level, and insulin-stimulated glucose uptake in both leg and arm muscles to lower high blood sugar levels.

The cycling groups in the Mayo Clinic study either pedaled at a moderate pace for 30 minutes or did interval training consisting of pedaling intensely for four minutes, resting for three minutes and then repeating each interval three more times. Just three interval workouts a week for 12 weeks reversed some of the effects of aging on muscles. The bicycle-interval riders had the greatest gains in the number and function of their muscle mitochondria, a marker of the ability to turn food into energy. The mitochondria in muscles of the interval-exercising people over 65 were able to convert food to energy as efficiently as those in people under 30 years of age.

The weightlifting groups of the Mayo Clinic study either lifted heavy weights intensely or light weights slowly. Those who lifted weights more intensely had greater gains in muscle size and strength. However, those who did bicycle interval training had the greatest gains in endurance.

Other studies have shown that resistance and interval training both help to control blood sugar levels and can cure some people who already have diabetes (Ann Intern Med, Sept. 18, 2007;147(6):357-69). HBA1c blood tests that measure cell damage from diabetes can return to normal. The greatest improvement occurred in those who both lifted weights and performed aerobic training (Sports Med, April 2014;44(4):487-99). Furthermore, diabetics who can tolerate intense interval cycling gain superior improvement in blood sugar and insulin levels and drops in HBA1c, a measure of cell damage (Cardiovasc Diabetol, May 14, 2017;16(1):37).

Lowering High Blood Sugar Levels When blood sugar levels rise, the pancreas releases insulin that lowers blood sugar by driving sugar from the bloodstream into the liver. If the liver is full of fat, the liver does not accept the sugar and blood sugar levels remain high to damage every cell in your body, so people with high blood sugar levels must get fat out of their liver.

Resting muscles draw no sugar from the bloodstream and the little that they can draw needs insulin to do so. However, contracting muscles draw tremendous amounts of sugar from the bloodstream and do not even need insulin to do so. Having extra fat in muscles also limits the amount of sugar that can enter a muscle, so getting fat out of the muscles makes muscles more efficient in lowering high blood sugar levels.

If You Have High Blood Sugar Levels Having a normal fasting blood sugar level does not rule out diabetes. A high rise in blood sugar after meals can damage every cell in your body. If your blood sugar level one-hour-after-eating is greater than 140, your cells are being damaged and your life is being shortened. Other clues that your blood sugar is rising too high after you eat include: having more than two inches of fat under the skin when you pinch next to your belly button having a protruding belly having small buttocks being overweight having high triglycerides (>150), low good HDL cholesterol (<40), a sonogram that shows excess fat in your liver, or high systolic blood pressure at bedtime (>120).

My Recommendations If your blood sugar is greater than 140 one hour after a meal, Lose weight if overweight. Ask your doctor to help you try intermittent fasting (Surg Obes Relat Dis, Nov-Dec 2015;11(6):1315-22). Severely restrict refined carbohydrates (Clin Nutr, Oct 8, 2016). Most liver fat comes from sugar and other refined carbohydrates (J Clin Invest, May 2005;115(5):1343-51). Severely restrict all sugared drinks including fruit juices (J Clin Endocrinol Metab, Jun 2015;100(6):2434-42). Restrict red meat, processed meat and fried foods that block insulin receptors (JAMA Intern Med, 2013;173(14):1328-1335). Eat plenty of vegetables, seeds and nuts which are rich sources of soluble fiber (Clin Transl Gastroenterol, Jun 2016;7(6):e176). Try to exercise every day (Diabetologia, Jan 2016;59(1):56-66).

Caution:Intense exercise can cause heart attacks in people who already have blocked arteries. Check with your doctor before starting an exercise program or increasing the intensity of your existing program.

Dr. Gabe Mirkin is a Villager. Learn more at http://www.drmirkin.com

Visit link:
Treat diabetes with diet and exercise | Villages-News.com - Villages-News

Gordon Bell/Shutterstock

A huge study has revealed what we need to be eating every day to lower our risk of diabetes and related vascular complications. Unfortunately, its not ice cream or friesbut it is a simple dietary addition that most of us can easily make: fresh fruit.

Huaidong Du, MD, PhD, of Oxford University, England, led the Chinese epidemiological study, which included half a million people and was reported online in PLOS Medicine. According to the research team, each daily portion of fruit consumed linked to a 12 percent reduction in diabetes risk, an association not significantly modified by sex, age, region, survey season, or a range of other factors including smoking, alcohol consumption, physical activity, body mass index, and family history of the disease. (Find out the difference between type 1 and type 2 diabetes.)

To our knowledge, this is the first large prospective study demonstrating similar inverse associations of fruit consumption with both incident diabetes and diabetic complications, writes Du and colleagues. In lay language, this means that the more fruit you eat, the lower your risk of diabetes and diabetes complications. These findings suggest that a higher intake of fresh fruit is potentially beneficial for primary and secondary prevention of diabetes (Here are more foods that should be in a diabetic diet.)

Previous research on how to prevent diabetes with fruit consumption has focused mainly on Western populations and typically included processed fruitinstead of only fresh fruit in the Chinese study. Because Chinese people with the disease are likely to cut fresh fruit from their diets due to a mistaken belief that any sweet-tasting food will raise their blood sugar, this may explain the very strong association in this study. Nonetheless, clinicians and nutritionists the world over are likely to be celebrating the findings.

And the good fruit news doesnt end there: A separate study, carried out by the University of Eastern Finland and published online in Scientific Reports, found that the healthy bacteria that form in the gut when we eat fiber can be protective against the disease. Guess what has a ton of fiber? Yes, thats rightfruit.

Be aware, however, that you can get too much of a good thingeven fruit. The World Health Organization recommends 400 grams of fruit and vegetables per day for diabetes prevention (as well other chronic diseases such as heart disease, cancer, and obesity), and theres no need to go way over that amount. Nutritionist Abby Langer, RD, told Self that eating too much fruit can actually cause health issues like bloating, fatigue, weight gain, or trouble losing weight, and over time can result in heightened triglycerides (fat in the blood associated with how much sugar you eat) and high blood sugar levels.

So how many pieces of fruit is the ideal per day? Shoot for five servings of different fruits (in addition to vegetables) daily. If possible, choose from these superfood fruits.

Originally posted here:
If Diabetes Runs in Your Family, You NEED to Read the Latest Study on Fruit - Reader's Digest