By Dr. Allan Frankel, M.D. Greenbridge Medical

March 28, 2017 On Diabetes AlertDay it is fitting to discuss not only attempts at managing the disease, but also contributing factors and other conditions related to the disease.

For some time I have been recommending whole plant cannabis CBD for patients with Diabetes. We have seen a substantial lowering of their glucose levels in those with Type II Diabetes including several patients Hemoglobin A1C levels normalize so they are able to stop their Type II Diabetes medications.

The first time I saw this with a Diabetic, he called me after having some hypoglycemic episodes while taking CBD in addition to his Metformin. I told him to stop his Metformin and continue his CBD. His glucose levels normalized and he remained off Metformin. This is a good demonstration of blood sugar control over a three-month period. With any patient with Type II Diabetes, I warn them about this.

With regard to cholesterol, Diabetes can raise bad cholesterol levels and lower good cholesterol levels. Once a patients blood sugar levels are stable, if they are on a statin I will often discuss with the patient and their primary care doc, the idea of stopping the statin and monitoring their cholesterol levels. The drop in cholesterol is not overnight. It can take some months for reasons we dont yet understand. However, we are seeing improvements in cholesterol levels and many patients remain off their statins.

We have also seen improvements ranging from apparent stabilization of macular degeneration and help with neuropathic pain. Sometimes combined with THC, CBD is a vascular and renal protectant.

Finally with regard to weight and Diabetes, there is certainly a connection to being overweight and the onset of Diabetes. I have written about the effect of CBD on curbing appetite before. The ability to achieve weight loss with CBD is real.

So, when discussing CBD and Diabetes, it is a multi-pronged approach. Helping patients with weight, cholesterol and glucose issues. I believe this is all happening on a number of metabolic levels, such as bringingthe sensitivity of insulin back to normal.

So, help with many major issues resulting from, and associated with diabetes can be achieved with CBD. For certain, it is worth a try.

2017 Greenbridge Medical. All rights reserved. Posted by special permission. Original article appeared here.

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Crain's Detroit Business

Michigan tests 'pay- for-success' model for diabetes prevention Crain's Detroit Business The model is set to get another early test drive in Michigan, expanding a proven diabetes prevention program offered by the National Kidney Foundation of Michigan in six Metro Detroit and West Michigan counties. For nonprofits, the model promises a new ...

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Michigan tests 'pay- for-success' model for diabetes prevention - Crain's Detroit Business

According to researchers, the results of their study illustrate the importance of intestinal bacteria's contribution to the operation of diet, metabolism and health interface.

Results were published in Scientific Reports magazine. The study was conducted at the University of Eastern Finland LC-MS-metabolomiikkakeskuksessa. The partners had a large number of Finnish and Swedish experts.

The study compared two groups who took part in a wider Diabetes Prevention study (DPS). Everyone had at the beginning of the study excess weight and impaired glucose tolerance. During 15 years of follow-up part of the ill with type 2 diabetes, some not. Differences between these two groups studied the unallocated metabolomics analysis. It can be studied to determine the metabolic profile of a concentration of a large number of metabolites rather than examining only a few of the predetermined marker.

The main differences with type 2 diabetes affected and unaffected metabolism profiles was observed at concentrations of the indole propionic acids and certain lipid metabolism products.

High serum concentration of the indole propionic acids were protected with diabetes illness. Indole propionic acids are intestinal bacteria metabolite. A generous use of whole grains, dietary fiber boosted its content. Indolipropionohapon a greater amount of the pancreatic beta-cell insulin secretion appeared to remain preferred, which may explain the protective effect.

Indole propionic contacting the risk of diabetes explained DPS material in addition to the two population-based study file, the file METSIM Finnish and Swedish VIP material. Also, there it turned out to be diabetes protective factor.

The study identified several new lipid metabolism products, with a high concentration was associated with improved insulin sensitivity and reduced the risk of diabetes. These metabolites content of the higher, the less of saturated fat diet. They, as well as the indole propionic acids, showed a high concentration of the protective body in low-grade inflammation of the farm.

- intestinal bacteria have been found in other studies to affect the risk of developing excess weight. In light of these results, the indole propionic acids may be one factor that mediates diet and intestinal bacteria a protective effect, academy researcher Kati Hanhineva says.

Direct determination of intestinal bacteria is difficult, so produced by the metabolism of intestinal bacteria intermediates assay may be useful in methods to examine the role of intestinal bacteria such as diabetes pathogenesis.

The DPS is the first randomized controlled lifestyle intervention study, which demonstrated that type 2 diabetes is preventable lifestyle changes in subjects with impaired glucose tolerance. Major lifestyle changes were weight loss, increased physical activity and a change in diet more in line with the recommendations of, for example, whole grain cereals, fruit and vegetables with respect to the use.

This article has been republished frommaterialsprovided byUniversity of Eastern Finland. Note: material may have been edited for length and content. For further information, please contact the cited source.

Reference

de Mello, V. D., Paananen, J., Lindstrm, J., Lankinen, M. A., Shi, L., Kuusisto, J., ... & Bergdahl, I. A. (2017). Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Scientific Reports, 7.

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I wish I could say I was a friend of Mary Tyler Moores, she surely made you feel that way. There was a time when she, or her beloved husband Robert, and I would pass and a hello was stated. We knew of each other in the same battle. Shewrote a wonderful inscriptionin her book when she sent it to me to thank me on a specific project we worked on together and I will cherish it forever.

She THANKED me. Really? Like I could ever be on par with what she had done over the years. We worked together on fundraising, Washington DC advocating, and when it came to ANYTHING diabetes..rest assured Mary was there in full forcehow lucky was I to have just a little piece of life with this incredible woman.

Its not often one gets to work with an icon, with a person who has her character-genetic pool somewhere in almost every comedic character to appear on TVshe was not the bestshe was thebest of the best and she did it-while battling diabetes.

I have stated it before, and will always feel the same, no one in the celebrity world came close to do for the world of diabetes than what Mary Tyler Moore accomplished with JDRF. Her efforts were tireless over the years. She would attend events, meet with elected officials, testify before congress and yet, it was when she met those who lived like her.with diabetes, that I will remember most. The time she took to speak to them and relate to them, to tell them they would be okay..that is theMary I will remember most.

Every organization under the sun wishes they had a spokesperson the caliber of Mary Tyler Moore. Her connection with JDRF (and what was then JDF) was, and is, legendary. She loved the JDRF and thepeople involved with the organization. How fortunate they are, and were, to have Mary as part of their family. My heart goes out to the manywho worked with her at theJDRF, especially Karen Brownlee, who worked with Mary foryears as the Liaison between theJDRF and Marys people.

Mary had but one goal when it came to diabetes.to bring to the attention of the world the battle of diabetes and how important it is to one day cure it. How important it is to handle it. Perhaps if she meant something to you, you can give a donation to JDRF in her memory. Mary would want it done that way. I did. Its the least I could do for the woman who taught me to fight diabetes with as much fierceness as possible and at the same time; tryto turn the world on with a smile..which no one did better than Mary Tyler Moore

Rest in Peace friend, and thank you. Iam a DiabetesDad.

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Diabetes Dad: No One was Better for Diabetes Causes than Mary.RIP - Diabetes Health (press release)

Dr. Gabe Mirkin

Recent studies show that the high blood sugar of diabetes is caused by excess fat in: the liver (JAMA, February 14, 2017), the muscles (J Cardiovascular Pharmacology and Therapeutics, April 2017) and the pancreas ((Diabetes Care, December 2015). Diabetes can be treated and often cured with: exercise that removes fat from muscles (Scandinavian Journal of Medicine & Science in Sports, March 13, 2017;27(5)) and diets that remove fat from the liver and other organs (Diabetologia, 2011 Oct; 54(10): 25062514).

The Studies A study from Finland shows that high-intensity interval training rapidly lowers blood sugar levels and increases a Type II diabetics cell response to insulin (Scan J Med & Sci in Sprts, March 13, 2017;27(5)). Both healthy and diabetic patients, 40-50 years old, performed either continuous exercise or 4-6 repetitions of 30 seconds of all-out cycling with four- minute recoveries between each interval, three times a week for two weeks. At the end of just six workouts in two weeks, the thigh muscles of diabetics were able to remove the same amount of sugar from the bloodstream as the thigh muscles of non-diabetics. This means that the muscles of diabetics were able to clear sugar from the bloodstream in a normal manner.

In another study, researchers at the Mayo Clinic showed that both weightlifting and cycling reversed some of the effects of aging on muscles (Cell Metabolism, March 2017;25(3):581592). Both types of exercise increased: endurance, fitness level, and insulin-stimulated glucose uptake in both leg and arm muscles to lower high blood sugar levels.

The cycling groups in the Mayo Clinic study either pedaled at a moderate pace for 30 minutes or did interval training consisting of pedaling intensely for four minutes, resting for three minutes and then repeating each interval three more times. Just three interval workouts a week for 12 weeks reversed some of the effects of aging on muscles. The bicycle-interval riders had the greatest gains in the number and function of their muscle mitochondria, a marker of the ability to turn food into energy. The mitochondria in muscles of the interval-exercising people over 65 were able to convert food to energy as efficiently as those in people under 30 years of age.

The weightlifting groups of the Mayo Clinic study either lifted heavy weights intensely or light weights slowly. Those who lifted weights more intensely had greater gains in muscle size and strength. However, those who did bicycle interval training had the greatest gains in endurance.

Other studies have shown that resistance and interval training both help to control blood sugar levels and can cure some people who already have diabetes (Ann Intern Med, Sept. 18, 2007;147(6):357-69). HBA1c blood tests that measure cell damage from diabetes can return to normal. The greatest improvement occurred in those who both lifted weights and performed aerobic training (Sports Med, April 2014;44(4):487-99). Furthermore, diabetics who can tolerate intense interval cycling gain superior improvement in blood sugar and insulin levels and drops in HBA1c, a measure of cell damage (Cardiovasc Diabetol, May 14, 2017;16(1):37).

Lowering High Blood Sugar Levels When blood sugar levels rise, the pancreas releases insulin that lowers blood sugar by driving sugar from the bloodstream into the liver. If the liver is full of fat, the liver does not accept the sugar and blood sugar levels remain high to damage every cell in your body, so people with high blood sugar levels must get fat out of their liver.

Resting muscles draw no sugar from the bloodstream and the little that they can draw needs insulin to do so. However, contracting muscles draw tremendous amounts of sugar from the bloodstream and do not even need insulin to do so. Having extra fat in muscles also limits the amount of sugar that can enter a muscle, so getting fat out of the muscles makes muscles more efficient in lowering high blood sugar levels.

If You Have High Blood Sugar Levels Having a normal fasting blood sugar level does not rule out diabetes. A high rise in blood sugar after meals can damage every cell in your body. If your blood sugar level one-hour-after-eating is greater than 140, your cells are being damaged and your life is being shortened. Other clues that your blood sugar is rising too high after you eat include: having more than two inches of fat under the skin when you pinch next to your belly button having a protruding belly having small buttocks being overweight having high triglycerides (>150), low good HDL cholesterol (<40), a sonogram that shows excess fat in your liver, or high systolic blood pressure at bedtime (>120).

My Recommendations If your blood sugar is greater than 140 one hour after a meal, Lose weight if overweight. Ask your doctor to help you try intermittent fasting (Surg Obes Relat Dis, Nov-Dec 2015;11(6):1315-22). Severely restrict refined carbohydrates (Clin Nutr, Oct 8, 2016). Most liver fat comes from sugar and other refined carbohydrates (J Clin Invest, May 2005;115(5):1343-51). Severely restrict all sugared drinks including fruit juices (J Clin Endocrinol Metab, Jun 2015;100(6):2434-42). Restrict red meat, processed meat and fried foods that block insulin receptors (JAMA Intern Med, 2013;173(14):1328-1335). Eat plenty of vegetables, seeds and nuts which are rich sources of soluble fiber (Clin Transl Gastroenterol, Jun 2016;7(6):e176). Try to exercise every day (Diabetologia, Jan 2016;59(1):56-66).

Caution:Intense exercise can cause heart attacks in people who already have blocked arteries. Check with your doctor before starting an exercise program or increasing the intensity of your existing program.

Dr. Gabe Mirkin is a Villager. Learn more at http://www.drmirkin.com

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A huge study has revealed what we need to be eating every day to lower our risk of diabetes and related vascular complications. Unfortunately, its not ice cream or friesbut it is a simple dietary addition that most of us can easily make: fresh fruit.

Huaidong Du, MD, PhD, of Oxford University, England, led the Chinese epidemiological study, which included half a million people and was reported online in PLOS Medicine. According to the research team, each daily portion of fruit consumed linked to a 12 percent reduction in diabetes risk, an association not significantly modified by sex, age, region, survey season, or a range of other factors including smoking, alcohol consumption, physical activity, body mass index, and family history of the disease. (Find out the difference between type 1 and type 2 diabetes.)

To our knowledge, this is the first large prospective study demonstrating similar inverse associations of fruit consumption with both incident diabetes and diabetic complications, writes Du and colleagues. In lay language, this means that the more fruit you eat, the lower your risk of diabetes and diabetes complications. These findings suggest that a higher intake of fresh fruit is potentially beneficial for primary and secondary prevention of diabetes (Here are more foods that should be in a diabetic diet.)

Previous research on how to prevent diabetes with fruit consumption has focused mainly on Western populations and typically included processed fruitinstead of only fresh fruit in the Chinese study. Because Chinese people with the disease are likely to cut fresh fruit from their diets due to a mistaken belief that any sweet-tasting food will raise their blood sugar, this may explain the very strong association in this study. Nonetheless, clinicians and nutritionists the world over are likely to be celebrating the findings.

And the good fruit news doesnt end there: A separate study, carried out by the University of Eastern Finland and published online in Scientific Reports, found that the healthy bacteria that form in the gut when we eat fiber can be protective against the disease. Guess what has a ton of fiber? Yes, thats rightfruit.

Be aware, however, that you can get too much of a good thingeven fruit. The World Health Organization recommends 400 grams of fruit and vegetables per day for diabetes prevention (as well other chronic diseases such as heart disease, cancer, and obesity), and theres no need to go way over that amount. Nutritionist Abby Langer, RD, told Self that eating too much fruit can actually cause health issues like bloating, fatigue, weight gain, or trouble losing weight, and over time can result in heightened triglycerides (fat in the blood associated with how much sugar you eat) and high blood sugar levels.

So how many pieces of fruit is the ideal per day? Shoot for five servings of different fruits (in addition to vegetables) daily. If possible, choose from these superfood fruits.

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If Diabetes Runs in Your Family, You NEED to Read the Latest Study on Fruit - Reader's Digest