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Sanford School of Medicine | USD – University of South Dakota

Posted: October 19, 2015 at 5:51 pm

Presenter: Michael Leon, PhD, Professor and Associate Dean, Department of Neurobiology and Behavior, Center for Autism Research and Translation, Center for the Neurobiology of Learning and Memory, The University of California, Irvine, California. Location: Sanford USD Medical Center Schroeder Auditorium Avera Education Center Classroom 2 (Avera sites dial in to 8103502) The VA Hospital Room 351, and registered video conferencing sites

Presenter: Sam Milanovich, MD, Assistant Professor, Department of Pediatrics, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. Location: Health Science Center Room 106 Sioux Falls, SD Avera Education Center Classroom 2 (Avera sites dial in to 8103502) The VA Hospital Room 351, and registered video conferencing sites

Presenter: Jenny Miller, DC, Chiropractor/Acupuncture, Sioux Falls VA Hospital Location: VA Education Center, Building One, Room #123, Sioux Falls, South Dakota

Presenter: Jerome Freeman, MD, FACP, Professor and Chair, Department of Neurosciences, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota Location: Sanford USD Medical Center Schroeder Auditorium, Avera Education Center Classroom 3 (Avera sites dial in to 8103502) The VA Hospital Room 351, and registered video conferencing sites

Presenter: Anthony Sierra, MD, Clinical Professor, Department of Obstetrics and Gynecology, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota Location: Schroeder Auditorium, Sanford USD Medical Center Sioux Falls, South Dakota

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Sanford School of Medicine | USD - University of South Dakota

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Health Sciences South Carolina

Posted: October 19, 2015 at 5:51 pm

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Cryopreservation of Hematopoietic Stem Cells

Posted: October 19, 2015 at 5:51 pm

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Chapter 3: On the Job: Cellular Specialties: Inside the …

Posted: October 19, 2015 at 5:51 pm

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OHSU research team successfully converts human skin cells …

Posted: October 19, 2015 at 5:50 pm

05/15/13Portland, Ore.

The breakthrough marks the first time human stem cells have been produced via nuclear transfer and follows several unsuccessful attempts by research groups worldwide

Update 05/23/2013: OHSU releases statement on questions about photos in stem cell paper. Read the statement.

Scientists at Oregon Health & Science University and the Oregon National Primate Research Center (ONPRC) have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body. It is believed that stem cell therapies hold the promise of replacing cells damaged through injury or illness. Diseases or conditions that might be treated through stem cell therapy include Parkinsons disease, multiple sclerosis, cardiac disease and spinal cord injuries.

The research breakthrough, led by Shoukhrat Mitalipov, Ph.D., a senior scientist at ONPRC, follows previous success in transforming monkey skin cells into embryonic stem cells in 2007. This latest research will be published in the journal Cell online May 15 and in print June 6.

The technique used by Drs. Mitalipov, Paula Amato, M.D., and their colleagues in OHSUs Division of Reproductive Endocrinology and Infertility, Department of Obstetrics & Gynecology, is a variation of a commonly used method called somatic cell nuclear transfer, or SCNT. It involves transplanting the nucleus of one cell, containing an individuals DNA, into an egg cell that has had its genetic material removed. The unfertilized egg cell then develops and eventually produces stem cells.

A thorough examination of the stem cells derived through this technique demonstrated their ability to convert just like normal embryonic stem cells, into several different cell types, including nerve cells, liver cells and heart cells. Furthermore, because these reprogrammed cells can be generated with nuclear genetic material from a patient, there is no concern of transplant rejection, explained Dr. Mitalipov. While there is much work to be done in developing safe and effective stem cell treatments, we believe this is a significant step forward in developing the cells that could be used in regenerative medicine.

Another noteworthy aspect of this research is that it does not involve the use of fertilized embryos, a topic that has been the source of a significant ethical debate.

The Mitalipov teams success in reprogramming human skin cells came through a series of studies in both human and monkey cells. Previous unsuccessful attempts by several labs showed that human egg cells appear to be more fragile than eggs from other species. Therefore, known reprogramming methods stalled before stem cells were produced.

To solve this problem, the OHSU group studied various alternative approaches first developed in monkey cells and then applied to human cells. Through moving findings between monkey cells and human cells, the researchers were able to develop a successful method.

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OHSU research team successfully converts human skin cells ...

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Endothelial stem cell – Wikipedia, the free encyclopedia

Posted: October 19, 2015 at 5:50 pm

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Stem-cell niche – Wikipedia, the free encyclopedia

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JCI – Type 2 alveolar cells are stem cells in adult lung

Posted: October 19, 2015 at 5:49 pm

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New Mexico (Stem Cell) – what-when-how

Posted: October 19, 2015 at 5:49 pm

On July 18, 2006, the U.S. Senate convened to vote on a proposed bill (H.R. 810) that would amend the Public Health Service Act and provide federal funding for research on human embryonic stem cells. This bill was passed by the Senate but was later vetoed by President George W. Bush. In the vote, the two New Mexico Senators voted against each other: Democrat Jeff Bingaman was in favor of the bill and Republican Pete Domenici opposed it.

Also in 2006, New Mexico Governor Bill Richardson proposed a budget of $10 million of state funds to be dedicated to supporting stem cell research. The money would build a new research center at the Health Sciences Center of the University of New Mexico campus at Albuquerque (with an allocated $4 million), as well as hire research faculty (using another $4 million) and train graduate students for future careers in stem cell research (with the remaining $2 million). The purpose of using state funds to build the research center as well as to support faculty and students is to circumvent the federal law prohibiting stem cell research with federal funds. States, however, are free to choose their own stances on stem cell research. Governor Richardson was approached by New Mexicos Roman Catholic Bishops, who urged him to reconsider his proposal to use embryonic stem cells.

In January 2008, the U.S. Senate again passed a bill in favor of allowing federal funds to support stem cell research while forbidding human cloning. This bill, 2008 Senate Bill 23, or the Biomedi-cal Research Act, was sponsored by New Mexico Senator John C. Ryan and was supported by Governor Bill Richardson.

At present, within the University of New Mexico Health Sciences Center (UNM HSC), there is a graduate training program in development and stem cell biology. Stem cell-related research focuses on embryonic stem cells in terms of their cell cycle and its regulation and how these regulatory schemes are related to those schemes of cancer cells, as well as neural stem cells and the harnessing of such cells to treat disorders such as Parkinsons disease, Alzheimers disease, and numerous other degenerative disorders. In addition, neural stem cells could be used to treat spinal cord injury patients, and further understanding of these stem cells could shed light on the molecular biology of brain tumors.

Another focus of the research at UNM HSC is on adult human renal stem cells. These cells can be harvested from the adult kidney and studied. Such investigations might lead to customized treatment of chronic kidney failure or other renal diseases. Scientists at UNM HSC also study human blood and bone marrow stem cells.

Another university in New Mexico, the New Mexico State University (NMSU), also recognizes the importance of stem cell research. Although little research that is directly related to stem cells is carried out at NMSU, scientists there are encouraged to stay abreast of the biological science regarding stem cells. In fact, the main Web page of the office of the vice president for research highlights stem cell research breakthroughs in its Global Research News Section. Smaller universities such as the Eastern University of New Mexico and the Western

University of New Mexico do not have the facilities to conduct stem cell research, yet they keep their students and faculty informed through classes and seminars that address stem cell biology.

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New Mexico (Stem Cell) - what-when-how

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The New Jersey Cord Blood Bank (NJCBB)

Posted: October 19, 2015 at 5:49 pm

Our state-designated public bank allows you to donate your baby's umbilical cord blood at participating hospitals in New Jersey so his or her stem cells can be used by a child or adult suffering from cancer or another life-threatening disease anywhere in the world.

Stem cell transplants are being used in the treatment of leukemia, lymphoma, Hodgkin's disease, sickle cell anemia, cerebral palsy, aplastic anemia and various other cancers, blood diseases, hereditary conditions and immune system disorders. In the future, stem cells may be used to fight heart disease, breast cancer, diabetes, Parkinsons disease, Alzheimers disease, multiple sclerosis, diabetes, Parkinsons disease, AIDS, and a score of other genetic diseases.

What are Stem Cells?

Stem cells are found concentrated in bone marrow and umbilical cord blood. Stem cells make the three types of blood cells that we need to survive: red cells to carry oxygen throughout our bodies, platelets to prevent bleeding and white cells to form our immune systems and guard us against infection. When stem cells are damaged or destroyed during aggressive treatment for cancer or other diseases, they can be replaced through bone marrow or cord blood transplants.

How Are Stem Cells Collected and Stored?

Why are More Ethnically and Racially Diverse Donors Needed?

Tissue types are inherited, so patients are more likely to match someone who shares their racial or ethnic heritage. As the need for transplants in diverse communities continues to grow, more ethnically and racially diverse donors are also needed from African American and Black, Hispanic, Latino, Asian and Native American communities to increase the chances of finding lifesaving matches for patients in need in those communities. A key goal of the NJCBB is to increase education and recruitment efforts within the State of New Jerseys diverse communities in an effort to save more lives.

What is the NJCBB?

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The New Jersey Cord Blood Bank (NJCBB)

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