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American Spine offers experimental fix for pain

Posted: January 28, 2015 at 1:57 pm

Doctors at American Spine in Germantown and throughout the State of Maryland have rolled out a new experimental set of regenerative treatments for injuries ranging from torn muscles to serious back pain and patients are starting to take notice.

Frank Chilcoat received his first platelet rich plasma injection on Dec. 2 for what he described as, Two tears on the outer part of my shoulder in the muscle.

Ive actually seen some difference already, Chilcoat said. My range of motion was very bad. I was limited and I would get pain.

Platelet rich plasma injections and stem cell therapies are under American Spines umbrella term of Regenerative Medicine Therapy, which the practice describes as the application of biological therapies that enhance the bodys ability to heal itself.

American Spine has several different locations, including one in Olney and another in a brand new building in Germantown, which will be a fully functioning surgical facility. As of now, any of the surgical locations can offer the regenerative treatments on site.

Dr. Mike Yuan has been spearheading the procedures at American Spine.

The [platelet rich plasma] procedure is a very simple process. Draw blood, like a blood test, then centrifuge the blood, Yuan said, explaining that the centrifuge separates the components of the blood isolating the plasma that helps bodies heal.

Next, doctors inject the patients own plasma back into the problem area, focusing their healing functions directly on site.

Instead of waiting for your body to take it to the site, we are injecting there, Dr. Sandeep Sherlekar, a co-owner of American Spine, said.

This procedure uses the bodys natural method of healing in a more effective way, giving the body the green light to send more healing cells to help out.

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American Spine offers experimental fix for pain

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American Spine offers experimental fix for pain — Gazette.Net

Posted: January 28, 2015 at 1:57 pm

Doctors at American Spine in Germantown and throughout the State of Maryland have rolled out a new experimental set of regenerative treatments for injuries ranging from torn muscles to serious back pain and patients are starting to take notice.

Frank Chilcoat received his first platelet rich plasma injection on Dec. 2 for what he described as, Two tears on the outer part of my shoulder in the muscle.

Ive actually seen some difference already, Chilcoat said. My range of motion was very bad. I was limited and I would get pain.

Platelet rich plasma injections and stem cell therapies are under American Spines umbrella term of Regenerative Medicine Therapy, which the practice describes as the application of biological therapies that enhance the bodys ability to heal itself.

American Spine has several different locations, including one in Olney and another in a brand new building in Germantown, which will be a fully functioning surgical facility. As of now, any of the surgical locations can offer the regenerative treatments on site.

Dr. Mike Yuan has been spearheading the procedures at American Spine.

The [platelet rich plasma] procedure is a very simple process. Draw blood, like a blood test, then centrifuge the blood, Yuan said, explaining that the centrifuge separates the components of the blood isolating the plasma that helps bodies heal.

Next, doctors inject the patients own plasma back into the problem area, focusing their healing functions directly on site.

Instead of waiting for your body to take it to the site, we are injecting there, Dr. Sandeep Sherlekar, a co-owner of American Spine, said.

This procedure uses the bodys natural method of healing in a more effective way, giving the body the green light to send more healing cells to help out.

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American Spine offers experimental fix for pain -- Gazette.Net

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Researchers advance the science behind treating patients with corneal blindness

Posted: January 28, 2015 at 1:47 pm

LOS ANGELES (Jan. 27, 2015) - Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness.

Scientists used human corneal cells to generate pluripotent stem cells that have a capacity to become virtually any body cell. Then, putting these cells on natural scaffolds, researcher's facilitated differentiation of these stem cells back to corneal cells.

"Our research shows that cells derived from corneal stem cells are attractive candidates for generating corneal cells in the laboratory," said Alexander Ljubimov, PhD, director of the Eye Program at the Board of Governors Regenerative Medicine Institute and principal investigator on this research study.

This research, published in the journal Stem Cells Translational Medicine, marks an important first step toward creating a bank of corneal stem cells that may potentially benefit patients who suffer from many forms of corneal blindness. The group is now working to optimize the process with National Institutes of Health funding.

Corneal deficiencies may have genetic or inflammatory roots or be caused by injuries, like burns to the skin in occupational accidents. They result in damage or death of stem cells that renew the outermost part of the cornea. If left untreated, they often cause compromised vision or blindness.

Over 150,000 Americans and more than 3 million individuals worldwide are affected by corneal blindness.

###

Study collaborators include Clive Svendsen, PhD, director of the Board of Governors Regenerative Medicine Institute and professor of biomedical sciences and medicine; Dhruv Sareen, PhD, director of the Induced Pluripotent Stem Cell Core and assistant professor of biomedical sciences; Mehrnoosh Saghizadeh, PhD, assistant professor of biomedical sciences; Yaron Rabinowitz, MD, director of the Division of Ophthalmology Research; and Vincent A. Funari, PhD, director of the Genomics Core and assistant professor of pediatrics.

Citation: Sareen D, Saghizadeh M, Ornelas L, et al. Differentiation of human limbal-derived induced pluripotent stem cells into limbal-like epithelium. Stem Cells Transl Med. 2014; 3(9):1002-12.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Researchers advance the science behind treating patients with corneal blindness

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Functional Medicine Minute – Vitamin D Stops Breast Cancer Stem Cells In Their Tracks – Video

Posted: January 28, 2015 at 6:46 am


Functional Medicine Minute - Vitamin D Stops Breast Cancer Stem Cells In Their Tracks
Do you fear breast cancer? Does breast cancer run in your family? Would you be interested in a evidence-based way to prevent breast cancer? Dr. John Bartemus...

By: Dr. John Bartemus

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Functional Medicine Minute - Vitamin D Stops Breast Cancer Stem Cells In Their Tracks - Video

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20150124 , Success in skin cells cultured neural stem cells. – Video

Posted: January 28, 2015 at 6:46 am


20150124 , Success in skin cells cultured neural stem cells.
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By: byung jue Kim

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20150124 , Success in skin cells cultured neural stem cells. - Video

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Patient Testimonial 20 – Video

Posted: January 28, 2015 at 6:46 am


Patient Testimonial 20

By: Plexus Neuro and Stem Cell Research Centre

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Patient Testimonial 20 - Video

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Patient Testimonial 19 – Video

Posted: January 28, 2015 at 6:46 am


Patient Testimonial 19

By: Plexus Neuro and Stem Cell Research Centre

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Patient Testimonial 19 - Video

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Patient Testimonial 21 – Video

Posted: January 28, 2015 at 6:46 am


Patient Testimonial 21

By: Plexus Neuro and Stem Cell Research Centre

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Patient Testimonial 21 - Video

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Patient Testimonial 22 – Video

Posted: January 28, 2015 at 6:46 am


Patient Testimonial 22

By: Plexus Neuro and Stem Cell Research Centre

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Patient Testimonial 22 - Video

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Using stem cells to grow new hair

Posted: January 28, 2015 at 5:50 am

In a new study from Sanford-Burnham Medical Research Institute (Sanford-Burnham), researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss. The research was published online in PLOS One yesterday.

"We have developed a method using human pluripotent stem cells to create new cells capable of initiating human hair growth. The method is a marked improvement over current methods that rely on transplanting existing hair follicles from one part of the head to another," said Alexey Terskikh, Ph.D., associate professor in the Development, Aging, and Regeneration Program at Sanford-Burnham. "Our stem cell method provides an unlimited source of cells from the patient for transplantation and isn't limited by the availability of existing hair follicles."

The research team developed a protocol that coaxed human pluripotent stem cells to become dermal papilla cells. They are a unique population of cells that regulate hair-follicle formation and growth cycle. Human dermal papilla cells on their own are not suitable for hair transplants because they cannot be obtained in necessary amounts and rapidly lose their ability to induce hair-follicle formation in culture.

"In adults, dermal papilla cells cannot be readily amplified outside of the body and they quickly lose their hair-inducing properties," said Terskikh. "We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice."

"Our next step is to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects," said Terskikh. "We are currently seeking partnerships to implement this final step."

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The above story is based on materials provided by Sanford-Burnham Medical Research Institute. Note: Materials may be edited for content and length.

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