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Unlocking the secrets of stem cell generation – Video

Posted: December 14, 2014 at 12:44 am


Unlocking the secrets of stem cell generation
International scientists have carried out the most detailed study of how specialised body cells can be reprogrammed to be like cells from the early embryo. The findings are a major advance...

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Dr. Uta Grieshammer Nov 2014 – Video

Posted: December 14, 2014 at 12:44 am


Dr. Uta Grieshammer Nov 2014
Dr. Uta Grieshammer CIRM ugrieshammer@cirm.ca.gov Nov 2014 berkeley, calif East Bay Atheists vid capture with permission Did you know that without stem cells you would not be able to absorb...

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Will Jadeveon Clowney Return To Form After Microfracture Surgery? Timetable, Recovery Hard To Predict, Expert Says

Posted: December 13, 2014 at 2:00 pm

Houston Texans officials gave outside linebacker Jadeveon Clowney a projected recovery time of nine months after microfracture surgery Monday on his balky right knee. But its too soon to say if Clowney can meet that projection or regain the explosiveness that made him the No. 1 pick in the 2014 NFL Draft, according to one expert.

The great part of this operation is, its really safe, said Dr. Brian Cole, section head of the Cartilage Research and Restoration Center at Rush University Medical Center in Chicago and team physician for the Chicago Bulls and White Sox. The bad part of this operation is it doesnt always work.

Clowney has had two operations on his right knee during his rookie season in the NFL a concerning development for pass rusher who relies on his legs to generate the speed and power needed to reach the quarterback. The 21-year-old missed six games earlier this year after surgery to repair a torn meniscus in his right knee in September. During that operation, team doctors discovered damage to the knees articular cartilage the covering that protects the bone, sources told ESPN.

The University of South Carolina product attempted to play through the pain until it became clear that the injury was significantly limiting his effectiveness. The answer was microfracture surgery, a procedure sports fans have learned to dread since its development by Dr. Richard Steadman in the late 1980s. Texans general manager Rick Smith said the team expects a full recovery for Clowney.

The human body cannot naturally regrow or repair cartilage. Without adequate coverage from cartilage, the bones in the knee become overloaded. In the past, players who suffered from degenerative conditions in their knees were forced to either play through their pain or retire. Microfracture surgery offers an alternative, by drilling small holes into the area around the knee. This allows blood and stem cells to rush to area, protecting the knee and helping to promote healing in the affected area. But the resulting cartilage is not as strong as the real thing.

Once considered experimental, it is now the most commonly performed cartilage repair procedure, with some 130,000 to 160,000 microfracture surgeries performed each year, Cole said. And its largely effective Coles team conducted a study which found 83 percent of NBA players were able to return to the court six to 12 months after undergoing the procedure.

But basketball and football make different physical demands on the human body, and every patient has a different response to the operation. While the numbers suggest Clowney will return to the gridiron at some point in the future, theres no way to guarantee that it will happen in nine months or that Clowney will be the same player when he does return, Cole said.

Even under ideal conditions, the recovery window varies wildly from patient to patient, depending on the injurys location within the knee, as well as the knees overall condition. Some athletes may return to physical activity in four to six months, while others can delay for up to a year. Some microfracture patients do not regain full strength until approximately 15 months after the procedure.

You try to make projections and offer this linear thinking, if this, then that. But the honest answer is that you cant do it. Its very hard to predict, Cole said.

And a successful surgery would not necessarily prevent Clowney from experiencing future knee discomfort. At times, patients experience incomplete pain relief or a return of knee pain after a few years each of which would hinder an athletes ability to perform at the highest level of professional football.

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Will Jadeveon Clowney Return To Form After Microfracture Surgery? Timetable, Recovery Hard To Predict, Expert Says

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Royan using stem cells to treat kidney diseases

Posted: December 13, 2014 at 7:47 am

Source: Islamic Republic News Agency

Iranian researchers at Royan Institute are conducting clinical trials to treat chronic and acute kidney disease by using mesenchymal stem cells, an official said.

Royan Institute

Speaking on the sidelines of the 12th Asian Congress of Urology (ACU), Dr. Reza Moqaddas-Ali, the head of Kidney Group of Stem Cells Research Center affiliated to Royan Institute, added that the researchers have conducted animal trials successfully.

"Results of animal trials showed that mesenchymal stem cell treatment has been found to be a good treatment for acute kidney injury," he said.

"The treatment was not very effective in treating chronic kidney disease, but helps prevent progression of acute kidney injury to advanced chronic kidney disease."

Chronic kidney disease, also known as chronic renal disease, is a progressive loss in renal function over a period of months or years.

Acute kidney injury (AKI) is an abrupt loss of kidney function that develops within seven days.

Kidney Diseases

The ACU took place on Kish Island in southern Iran from December 5 to 9.

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Omnigen S.A – Biotechnology – Video

Posted: December 13, 2014 at 7:42 am


Omnigen S.A - Biotechnology
MUST WATCH VIDEO: This is how a living, beating heart is grown from stem cells.

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Dallas, Tx | SVF Stem Cell Therapy Testimonial (Knee Replacement Alternative) – Video

Posted: December 13, 2014 at 7:40 am


Dallas, Tx | SVF Stem Cell Therapy Testimonial (Knee Replacement Alternative)
http://www.innovationsStemCellCenter.com Call: 214.420.7970 Facebook: https://www.facebook.com/innovationsmedical Twitter: https://twitter.com/dallasdrj Inst...

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Dallas, Tx | SVF Stem Cell Therapy Testimonial (Knee Replacement Alternative) - Video

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Progress, challenges, and potential applications of oral stem cells – video abstract 51009 – Video

Posted: December 12, 2014 at 4:41 pm


Progress, challenges, and potential applications of oral stem cells - video abstract 51009
Video abstract of review paper From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells pu...

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What are stem cells? – Craig A. Kohn | TED-Ed

Posted: December 12, 2014 at 1:09 pm

Stem cells are a rapidly advancing field of biological research. Since Dr. James Thomson first cultivated human embryonic stem cells at the University of Wisconsin - Madison in the late 1990s, this field of researched has exploded with potential. The links below provide access to a curriculum developed under the supervision of Dr. Thomson as well as the co-directors and staff of the UW Stem Cell & Regenerative Medicine Center. The material has been reviewed for accuracy by the scientists actually conducting the research and was compiled and formatted by Craig Kohn, a high school teacher with research experience, for a high school audience. The PowerPoint presentation works in conjunction with the notesheet, allowing for students to work independently if preferred. More information about specific instructional practices can be found below in Teacher Notes.

PowerPoint: http://bit.ly/ted-stemcells

Notesheet: http://bit.ly/ted-stemcellsnotesheet

Quiz: http://bit.ly/ted-stemcellsquiz

Additional resources about stem cells can be found at:

http://www.stemcells.wisc.edu/node/386

http://stemcells.nih.gov/Pages/Default.aspxhttp://www.stemcellschool.org/http://www.nursingdegree.net/blog/750/25-best-blogs-for-following-stem-cell-research/

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Regenocyte is leading the medical industry in adult stem …

Posted: December 12, 2014 at 1:06 pm

2014 Stem Cell Pioneer Awards Stem Cell Awards Ceremony recognizing those pioneers in the field of Regenerative Therapy. Highlights of a few of the patients treated from 2006 to present. Treatments for heart, lung, neurologic and other diseases. Watch and see how some of the treated patients are doing -Awards Ceremony-Click here to watch the highlights

If you or a loved one suffer from severe heart, lung, or circulatory problems, it is possible that the latest therapies using adult stem cells can restore your quality of life to an unexpected level.

Because adult stem cell therapies are safe, simple, and minimally-invasive, they particularly help those who have exhausted the possibilities of other treatments.

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Irving Weissman, MD – Ludwig Center for Cancer Stem Cell …

Posted: December 12, 2014 at 1:06 pm

Dr. Weissmans laboratory is working on identifying and characterizing the progression of discrete changes, genetic and epigenetic, that leads to the generation of cancer stem cells (CSCs) from a variety of blood and solid tissue cancers. They have found a single molecular event present in all cancers studied to date that protects them from macrophages of the innate immune system.

Myelodysplastic Syndrome Investigators: Wendy Pang, Ravindra Majeti, Beverly Mitchell, Peter Greenberg, Jason Gotlib, Tena Cherry, and Irving Weissman

This group has proceeded with their work on myelodysplastic syndrome (MDS), a group of hematopoietic disorders characterized by ineffective and dysplastic myelopoiesis. Clinically, patients with MDS suffer from cytopenias and an increased risk for progression to acute myelogenous leukemia (AML).

Multiple Myeloma Investigators: Dongkyoon Kim, Bruno Medeiros, and Irving Weissman

In collaboration with Bruno Medeiros, MD, assistant professor of medicine (hematology), the laboratory is extending their work in multiple myeloma (MM), an incurable B-cell cancer. They have also investigated the coexistence of two tumor-initiating cell populations and their evolutionary hierarchy in a human myeloma cell line, RPMI 8226.

Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, and Lymphoma Investigators: Mark Chao, Max Jan, Ravindra Majeti, Ash Alizadeh, Sidd Jaiswal, and Irving Weissman

With a focus on the expression of CD47 on leukemia stem cells from AML and B-cell non-Hodgkin lymphoma (NHL) and its prognostic value, this group has made additional progress in the investigation of human AML and NHL in three major areas.

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