Page 2,013«..1020..2,0122,0132,0142,015..2,0202,030..»

Could stem cells from your hip repair your heart after an attack?

Posted: September 10, 2014 at 8:47 am

Father-of-two James Cross, 55, suffered a heart attack in February Surgeons at the London Chest Hospital offered him a unique chance Experimental therapy involved injecting stem cells from Mr Cross's hip into his heart in the hope they would encourage the organ to repair itself It appears to have worked as Mr Cross's heart muscle function has increased from 21% after the attack to 37% and it is still improving Experts hope the new technique will increase survival rates by a quarter

By John Naish

Published: 20:38 EST, 8 September 2014 | Updated: 07:12 EST, 9 September 2014

James Cross, 55,was offered experimental treatment after suffering a heart attack in February

After James Cross had a heart attack in February, he was given a unique chance for a new life.

Surgeons at the London Chest Hospital offered the 55-year-old experimental therapy that involved injecting his own stem cells into the damaged organ.

This was done in the hope that it would encourage his heart to repair itself.

The injected stem cells should prevent the hearts muscle tissue from becoming increasingly damaged after suffering a lack of oxygen during the heart attack.

And it seems to have worked.

After the heart attack, I had 21 per cent of my heart muscle functioning, as opposed to the normal 61 per cent, says James.

View post:
Could stem cells from your hip repair your heart after an attack?

Posted in Stem Cells | Comments Off on Could stem cells from your hip repair your heart after an attack?

Combining Antibodies, Iron Nanoparticles and Magnets Steers Stem Cells to Injured Organs

Posted: September 10, 2014 at 8:47 am

Contact Information

Available for logged-in reporters only

Newswise LOS ANGELES (STRICTLY EMBARGOED UNTIL SEPT. 10, 2014 at 5 A.M. EDT) Researchers at the Cedars-Sinai Heart Institute infused antibody-studded iron nanoparticles into the bloodstream to treat heart attack damage. The combined nanoparticle enabled precise localization of the bodys own stem cells to the injured heart muscle.

The study, which focused on laboratory rats, was published today in the online peer reviewed journal Nature Communications. The study addresses a central challenge in stem cell therapeutics: how to achieve targeted interactions between stem cells and injured cells.

Although stem cells can be a potent weapon in the fight against certain diseases, simply infusing a patient with stem cells is no guarantee the stem cells will be able to travel to the injured area and work collaboratively with the cells already there.

Infusing stem cells into arteries in order to regenerate injured heart muscle can be inefficient, said Eduardo Marbn, MD, PhD, director of the Cedars-Sinai Heart Institute, who led the research team. Because the heart is continuously pumping, the stem cells can be pushed out of the heart chamber before they even get a chance to begin to heal the injury.

In an attempt to target healing stem cells to the site of the injury, researchers coated iron nanoparticles with two kinds of antibodies, proteins that recognize and bind specifically to stem cells and to injured cells in the body. After the nanoparticles were infused into the bloodstream, they successfully tracked to the injured area and initiated healing.

The result is a kind of molecular matchmaking, Marbn said. Through magnetic resonance imaging, we were able to see the iron-tagged cells traveling to the site of injury where the healing could begin. Furthermore, targeting was enhanced even further by placing a magnet above the injured heart.

The Cedars-Sinai Heart Institute has been at the forefront of developing investigational stem cell treatments for heart attack patients. In 2009, Marbn and his team completed the world's first procedure in which a patient's own heart tissue was used to grow specialized heart stem cells. The specialized cells were then injected back into the patient's heart in an effort to repair and regrow healthy muscle in a heart that had been injured by a heart attack. Results, published in The Lancet in 2012, showed that one year after receiving the stem cell treatment, heart attack patients demonstrated a significant reduction in the size of the scar left on the heart muscle.

Earlier this year, Heart Institute researchers began a new study, called ALLSTAR, in which heart attack patients are being infused with allogeneic stem cells, which are derived from donor-quality hearts.

See the article here:
Combining Antibodies, Iron Nanoparticles and Magnets Steers Stem Cells to Injured Organs

Posted in Stem Cells | Comments Off on Combining Antibodies, Iron Nanoparticles and Magnets Steers Stem Cells to Injured Organs

MS stem-cell breakthrough led by Italians

Posted: September 10, 2014 at 8:41 am

'So far appears safe, without side effects'

(ANSA) - Boston, September 9 - Mesenchymal stem cell therapy to treat multiple sclerosis so far appears safe and without side effects, according to data released Tuesday and obtained through clinical trials on patients as part of the international Mesems project coordinated by University of Genoa neurologist Antonio Uccelli. The results were announced ahead of the World Congress on Treatment and Research in Multiple Sclerosis opening in Boston Wednesday through Saturday. The Mesems project involves researchers from nine countries - Italy, Spain, France, Britain, Sweden, Denmark, Switzerland, Canada and Australia. It is the first large phase II international multicentre clinical trial to determine the safety of a consensus treatment protocol established by the International Mesenchymal Stem Cells Transplantation Study Group to obtain information on its effectiveness on multiple sclerosis patients. So far, 81 patients have been involved in the project - half of the 160 needed for the whole clinical trial. About 73 - or 90% of those involved in blind testing - were given at least one injection with mesenchymal therapy or got a placebo while 51 - or 63% - were given both injections and 27 - 33% - completed the study. "The promising result is that so far none of these 27 people have suffered significant adverse events, which means that, so far, the treatment appears to be safe", said Uccelli. The neurologist warned that "caution is necessary" and that the effectiveness of the therapy can only be determined once the study is completed in 2016. Uccelli however added that preliminary studies on animals have persuaded researchers that mesenchymal stem cells "can halt inflammation on the central nervous system and probably succeed in protecting nervous tissue, even repairing it where damage is minor". Out of the 81 patients recruited so far, "28 are Italian and 10 of them have completed the study", Uccelli said, adding that all patients over the past year did relatively well except for one who was treated with placebo. The neurologist expressed the hope that "data in 2016 will give final confirmation that the therapy is effective so we can take the subsequent step with a larger phase III study aimed at demonstrating the role of stem cells as neurorepairers". Meanwhile Genoa's bioethics committee has approved a two-year extension of the project, which will be called Mesems Plus, "to verify, beyond the year of observation provided for by Mesems, the long-term safety of treatments in the study and the potential insurgence of adverse events in all those treated", said Uccelli.

See the original post:
MS stem-cell breakthrough led by Italians

Posted in Cell Therapy, Stem Cell Therapy | Comments Off on MS stem-cell breakthrough led by Italians

Barrett Foot & Ankle Institute Stem Cells – Video

Posted: September 9, 2014 at 10:44 pm


Barrett Foot Ankle Institute Stem Cells

By: Barrett Foot Ankle Institute

Link:
Barrett Foot & Ankle Institute Stem Cells - Video

Posted in Stem Cell Videos | Comments Off on Barrett Foot & Ankle Institute Stem Cells – Video

Delaware Stem Cell Treatment | Stem Cell Treatments

Posted: September 9, 2014 at 2:50 pm

Delaware Stem Cell Treatment Worldstemcells.com is one of the leading stem cell therapy and treatment providers for residents of Delaware and across the nation. Our cutting edge technology and compassionate staff truly set us apart from the competition. We are a US based company that understands your needs and concerns when looking for a stem cell treatment center. Our treatment center is located in Cancun, Mexico.

Conditions we treat include but not limited to:

Getting Started With Your Stem Cell Therapy and Treatments Here at World Stem Cells LLC we try to make the process of receiving stem cell transplants as easy as possible. We will help you figure out what your needs are and help you reach your goals as fast as possible. Follow the steps below on what to do.

Option 1 1.) Go to any page on our website and fill out the contact form. 2.) Fill in the required information and select the condition you would like to treat with stem cell therapy. 3.) Be sure to include any special information in the comments section. 4.) Click the submit button and we will contact you in a timely manner. 5.) Thats it, youre done!!!

REQUEST INFORMATION NOW!

Option 2

Call 800-234-1693 and speak with a representative regarding your stem cell therapy needs and requirements.

See the original post here:
Delaware Stem Cell Treatment | Stem Cell Treatments

Posted in Delaware Stem Cells | Comments Off on Delaware Stem Cell Treatment | Stem Cell Treatments

Kiessling lab finds impact of surface conditions on stem cell growth

Posted: September 9, 2014 at 2:48 pm

University of Wisconsin-Madison chemistry professor Laura Kiessling and her lab published new findings regarding stem cell differentiation Monday, according to a university press release.

Kiesslings study, which was published in the Proceedings of the National Academy of Sciences, describes how the qualities of surfaces on which pluripotent stem cells are grown affect the fate of these cells.

Kiesslings lab conducted research by placing pluripotent stem cells on brain tissue-like surfaces and observing their differentiation. Among other conclusions, the researchers found surface quality alone could influence cells to become neurons, according to the release.

Pluripotent stem cells are those that have yet to be assigned a specific role, thus they have potential to develop into any adult cell in the body.

The lab, directed by Kiessling and led by UW-Madison chemistry graduate student Samira Musah, created three types of gels to mimic liver, muscle and brain tissue.

The researchers found the cells on stiffer surfaces maintained a stem cell state, whereas those moved to a softer surface started to become neurons.

It was stunning to me that the surface had such a profound effect, Kiessling said in the release.

According to the release, the researchers believe the brain tissue-like surface quality affects the yes-associated protein 1, a potent oncogene, inside the cell.

YAP can be found either in the cytoplasm or nucleus of a cell. When located in the nucleus, YAP regulates gene expression.

Kiesslings study reports YAP is excluded from the nucleus when on soft surfaces, which helps direct the stem cells into brain cell development.

View original post here:
Kiessling lab finds impact of surface conditions on stem cell growth

Posted in Wisconsin Stem Cells | Comments Off on Kiessling lab finds impact of surface conditions on stem cell growth

Okyanos Cardiac Cell Therapy Clinic Scheduled to Open

Posted: September 9, 2014 at 2:40 pm

Freeport, Grand Bahama (PRWEB) September 08, 2014

Adult stem cell therapy for heart disease has emerged as a new treatment alternative for those living with a poor quality of life as a result of severe coronary artery disease. Okyanos is slated to begin delivering this innovative new treatment in the next several weeks, and is now screening qualified heart disease candidates. The procedure will be performed in their newly constructed state-of-the-art Phillips catheterization lab, as announced last month.

Just 50 miles from US shore, Okyanos cardiac cell therapy is available to qualified patients with advanced stages of coronary artery disease (CAD) and congestive heart failure (CHF). The screening process consists of a thorough review of your medical history by the Okyanos Chief Medical Officer and Cardiologist, Dr. Howard Walpole, as well as consultation done in conjunction with your cardiologist. You must be able to travel as the protocol is delivered in Freeport on Grand Bahama Island.

"As a leader in cardiac cell therapy, Okyanos is very excited to bring this innovative treatment and new standard of care to patients in a near-shore, regulated jurisdiction, said Matt Feshbach, CEO and co-founder of Okyanos. Our innovative treatment will restore blood flow to the heart helping it begin the process of healing itself, thereby improving the quality of life for heart disease patients who have exhausted all other options.

Over 12 million Americans suffer from some form of heart disease costing $108.9 billion dollars annually in the US alone. Several million patients have now exhausted the currently available methods of treatment but continue to suffer daily from chronic heart disease symptoms such as shortness of breath, fatigue and chest discomfort that can make simple activities challenging. Cardiac cell therapy stimulates the growth of new blood vessels which can lead to reduced angina and reduced re-hospitalizations resulting in an improvement in quality of life.

The Okyanos procedure is performed by prestigious US-licensed chief cardiologist, Dr. Howard Walpole. It is the first cardiac cell therapy procedure for heart failure and disease available outside of clinical trials in which the bodys own adult stem cells, derived from fat tissue, are injected directly into the damaged part of the heart via a catheter to restore blood flow and repair tissue damaged by a heart attack or disease.

The procedure begins with the extraction of a small amount of your body fat, a process done using advanced water-assisted liposuction technology. After separating the fat tissue using a European Union-approved cell processing device the Okyanos cardiologist immediately injects these cells into and around the low blood flow regions of the heart via a cathetera protocol which allows for better targeting of the cells to repair damaged heart tissue. Because the treatment is minimally invasive it requires that patients be under only moderate sedation. Post-procedural recovery consists of rest in a private suite for several hours that comfortably accommodates up to 3 family members.

Okyanos Heart Institute is scheduled to begin delivery in the next several weeks. Patients can contact Okyanos at http://www.Okyanos.com or by calling toll free at 1-855-659-2667.

About Okyanos Heart Institute: (Oh key AH nos) Based in Freeport, Grand Bahama, Okyanos Heart Institutes mission is to bring a new standard of care and a better quality of life to patients with coronary artery disease using cardiac stem cell therapy. Okyanos adheres to U.S. surgical center standards and is led by CEO Matt Feshbach and Chief Medical Officer Howard T. Walpole Jr., M.D., M.B.A., F.A.C.C., F.A.C.A.I. Okyanos Treatment utilizes a unique blend of stem and regenerative cells derived from ones own adipose (fat) tissue. The cells, when placed into the heart via a minimally-invasive catheterization, stimulate the growth of new blood vessels, a process known as angiogenesis. Angiogenesis facilitates blood flow in the heart and supports intake and use of oxygen (as demonstrated in rigorous clinical trials such as the PRECISE trial). The literary name Okyanos, the Greek god of the river Okeanos, symbolizes restoration of blood flow.

Read this article:
Okyanos Cardiac Cell Therapy Clinic Scheduled to Open

Posted in Stem Cell Therapy | Comments Off on Okyanos Cardiac Cell Therapy Clinic Scheduled to Open

Study sheds light on how stem cells can be used to treat lung disease

Posted: September 9, 2014 at 4:49 am

PUBLIC RELEASE DATE:

9-Sep-2014

Contact: Lauren Anderson lauren.anderson@europeanlung.org 1-142-672-876 European Lung Foundation http://www.twitter.com/EuropeanLung

Munich, Germany: A new study has revealed how stem cells work to improve lung function in acute respiratory distress syndrome (ARDS).

Previous studies have shown that stem cells can reduce lung inflammation and restore some function in ARDS, but experts are not sure how this occurs. The new study, which was presented at the European Respiratory Society's International Congress today (09 September 2014), brings us a step closer to understanding the mechanisms that occur within an injured lung.

ARDS is a life-threatening condition in which the efficiency of the lungs is severely reduced. It is caused by damage to the capillary wall either from illness or a physical injury, such as major trauma. ARDS is characterised by excessive and dysregulated inflammation in the lung and patients require mechanical ventilation in order to breathe.

Although inflammation is usually a method by which the body heals and copes with an infection, when the inflammation is dysregulated it can lead to severe damage. Immune cells known as macrophages can coordinate the inflammatory response by driving or suppressing inflammation, depending on the stimulation.

The researchers investigated whether stem cells can affect the stimulation of the macrophages and promote the state in which they will suppress the inflammation.

They tested this in an animal model using human bone marrow-derived stem cells. Mice were infected with live bacteria to induce acute pneumonia and model the condition of ARDS. The results showed that treatment with stem cells led to significant reductions in lung injury, inflammation and improved bacterial clearance. Importantly, when stem cells were given to animals that had their macrophages artificially removed, the protective effect was gone. This suggests that the macrophages are an important part of the beneficial effects of stem cells seen in this model of ARDS.

These results were further supported by experiments where stem cells were applied to human macrophages in samples of fluid taken from lungs of patients with ARDS. Again, the stem cells were able to promote the anti-inflammatory state in the human macrophage cells. The authors have identified several proteins, secreted by the stem cells, that would be responsible for this effect.

See the article here:
Study sheds light on how stem cells can be used to treat lung disease

Posted in Stem Cells | Comments Off on Study sheds light on how stem cells can be used to treat lung disease

Coming Together For A Cures 6th Annual Benefit for Duchennes Muscular Dystrophy in Wichita, Kansas On Saturday …

Posted: September 9, 2014 at 4:44 am

Wichita, KS (PRWEB) September 09, 2014

Twenty-eight year-old Ryan Benton has lived with Duchenne Muscular Dystrophy his entire life. In 2009, he was fortunate enough to begin receiving adult stem cell treatments at the Stem Cell Institute in Panama City, Panama. These treatments have had a dramatic impact on Ryan by increasing his muscle strength, enhancing his sense of well being and improving his overall outlook on life.

After receiving his first stem cell treatments, Ryan, along with his siblings Lauren and Blake, recognized that very few people knew much about adult stem cell therapy. So together, they founded Coming Together for a Cure (CTFAC) as a means to raise awareness and funds. Their ultimate goal is to afford others the same opportunity that Ryan has been fortunate enough to receive.

Our family has been extremely blessed by having the opportunity for Ryan to receive adult stem cell treatments. The treatments have given him more strength, balance, endurance and an overall better physical wellbeing. By having this opportunity we hope to share awareness of adult stem cell therapy so that other families can benefit from this advancement in medicine as we have, said Sandra Renard, Ryans mother.

The annual Coming Together for a Cure benefit has grown tremendously over the years. At this years 6th annual event on Saturday September 13th, CTFAC is anticipating its largest crowd ever, of up to 1,000 attendees.

The venue, known as The Farm, is located at 5820 N. Ridge Rd. Wichita, KS 67205. Doors open to the general public at 6:00pm. Starting at 6:30, guests will be treated to live music and entertainment from classic rock, bluegrass and country music bands. Music from Kansas native and current Nashville recording artists, Jared Daniels Band starts at 8:30. Refreshments, concessions, adult beverages and food trucks will also be on hand.

Over the past five years the annual Coming Together for a Cure benefit has raised nearly $60,000. Money raised at each CTFAC event is donated to the Aidan Foundation, a 501(c)(3) non-profit organization founded by renowned stem cell scientist, Neil Riordan, PhD. The Aidan Foundation has funded Ryans treatments since 2009 and continues to provide ongoing funding.

Ryans father George Benton said, Ryan's stem cell treatment has truly become a dream come true. This dream was made possible by our wonderful friends and family who have generously given their talents, their love, and their financial support to Ryan in his quest for a cure. This effort proves that together, we can do anything.

CTFAC Contact Information:

Email: comingtogetherforacure(at)gmail(dot)com Website: comingtogetherforacure.org Facebook: http://www.facebook.com/comingtogetherforacure Twitter: @CTFACbenefit

Continue reading here:
Coming Together For A Cures 6th Annual Benefit for Duchennes Muscular Dystrophy in Wichita, Kansas On Saturday ...

Posted in Stem Cell Therapy | Comments Off on Coming Together For A Cures 6th Annual Benefit for Duchennes Muscular Dystrophy in Wichita, Kansas On Saturday …

Stem Cells | How Do Stem Cells Know Where To Go? – Video

Posted: September 8, 2014 at 3:44 pm


Stem Cells | How Do Stem Cells Know Where To Go?
Patients will often ask how stem cells know where to go? How do they know what they #39;re supposed to? This video provides a brief explanation answering those q...

By: Nathan Wei

See the article here:
Stem Cells | How Do Stem Cells Know Where To Go? - Video

Posted in Stem Cells | Comments Off on Stem Cells | How Do Stem Cells Know Where To Go? – Video

Page 2,013«..1020..2,0122,0132,0142,015..2,0202,030..»