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International Stem Cell Corporation to Present at Two Upcoming Investment Conferences

Posted: August 29, 2014 at 5:48 am

CARLSBAD, CA--(Marketwired - August 28, 2014) - International Stem Cell Corporation (OTCQB: ISCO) (www.internationalstemcell.com), a California-based biotechnology company developing novel stem cell based therapies and biomedical products, today announced that Executive Vice President Dr. Simon Craw will present a corporate overview of ISCO and its subsidiaries at two upcoming investment conferences.

Rodman and Renshaw 16th Annual Global Investment Conference:

Date:Wednesday, September 10, 2014 Time:11:40 a.m. ET Location:New York Palace Hotel, New York, NY Room:Kennedy I

Conference details:http://www.meetmax.com//sched/event_23003/~public/conference_home.html?event_id=23003

AEGIS CAPITAL Corp. 2014 Healthcare and Technology Conference:Date:Thursday, September 11, 2014 Time:10:45 a.m. PT Location:The Encore at Wynn, Las Vegas, NV

Conference details:http://www.meetmax.com/sched/event_25932/~public/conference_home.html?event_id=25932

Please contact the conference organizers if you have an interest in attending the conference or if you would like to arrange a meeting with International Stem Cell Corporation's management team.

About International Stem Cell Corporation

International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells (hpSCs) and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs) hence avoiding ethical issues associated with the use or destruction of viable human embryos. ISCO scientists have created the first parthenogenetic, homozygous stem cell line that can be a source of therapeutic cells for hundreds of millions of individuals of differing genders, ages and racial background with minimal immune rejection after transplantation. hpSCs offer the potential to create the first true stem cell bank, UniStemCell. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology (www.lifelinecelltech.com), and stem cell-based skin care products through its subsidiary Lifeline Skin Care (www.lifelineskincare.com). More information is available atwww.internationalstemcell.com.

To receive ongoing corporate communications via email, visit: http://www.b2i.us/irpass.asp?BzID=1468&to=ea&s=0.

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International Stem Cell Corporation to Present at Two Upcoming Investment Conferences

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BloodCenter of Wisconsin Launches Erythroid Chimerism Test for Monitoring Transplanted Sickle Cell Disease Patients

Posted: August 29, 2014 at 5:47 am

MILWAUKEE, Aug. 28, 2014 /PRNewswire-USNewswire/ -- BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of an innovative Erythroid Chimerism test to monitor erythroid lineage chimerism in patients with sickle cell disease (SCD) following allogeneic bone marrow transplantation. This allows the physician to directly gauge the success of the transplant in these patients and provides physicians with actionable information to guide patient care.

Sickle cell disease is a common and severe autosomal recessive disorder caused by a mutation in the hemoglobin gene. SCD affects approximately 100,000 people in the United States, one in every 300-500 African Americans. In SCD patients with severe clinical symptoms, allogeneic bone marrow transplantation can be used to replace the blood cell producing capacity, potentially curing them of the disease.1

In patients with SCD, several studies have demonstrated that standard chimerism assays do not always reflect chimerism in the erythroid lineage.2,3 Since red cells do not contain DNA, chimerism of the erythroid compartment can be monitored using HbA and HbS transcripts produced from the hemoglobin gene and expressed in red cell progenitors.

"Efficient and accurate monitoring for post-transplant therapy is critical in order to properly manage patient care," said Daniel Bellissimo, Ph.D., director of BloodCenter's Molecular Diagnostic Laboratory. "The addition of BloodCenter's Erythroid Chimerism test reflects its ongoing commitment to advancing patient care by providing physicians worldwide with leading-edge testing in the area of molecular testing."

BloodCenter's Diagnostic Laboratories help physicians provide clinical care to patients worldwide, fostering better understanding and treatment options for patients with difficult-to-diagnose diseases. In addition, the laboratories collaborate with other institutions and industry partners to bring new diagnostic testing and treatment options to patient care.

About BloodCenter of Wisconsin BloodCenter of Wisconsin is a not-for-profit organization that specializes in blood services, organ, tissue and marrow donation, diagnostic testing, medical services and leading-edge research. BloodCenter of Wisconsin is the only provider of blood to 56 hospitals in 29 Wisconsin counties as well as providing support to hospitals and patients across the country. BloodCenter of Wisconsin advances patient care by delivering life-saving solutions grounded in unparalleled medical and scientific expertise. For more information,visit http://www.bcw.edu.

References:

1) Bernaudin F., Socie G., Kuentz M., Chevret S., Duval M., Bertrand Y., et al. (2007) Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease. Blood 110: 27492756

2) Wu, Catherine, et al. Molecular assessment of erythroid lineage chimerism following nonmyeloablative allogeneic stem cell transplantation. Experimental Hematology (2003) 31: 924-933.

3) Andreanni, Marco et al. Quantitatively different red cell/ nucleated cell chimerism in patient with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease. Haematologica (2011) 96:128-133.

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BloodCenter of Wisconsin Launches Erythroid Chimerism Test for Monitoring Transplanted Sickle Cell Disease Patients

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Stem Cell Therapy for Chondromalacia Patella in Alta Wyoming

Posted: August 29, 2014 at 5:46 am

Looking for help with Chondromalacia Patella in Alta? Listed below are doctors and medical centers in and near Alta Wyoming.

If you are not looking for help with Chondromalacia Patella, check out the popular Chondromalacia Patella info on the right navigation area of the page. On the Chondromalacia Patella pages we include website links so you can check out Chondromalacia Patella online.

Are you searching for information about Chondromalacia Patella? Have you or someone you know been diagnosed with Chondromalacia Patella? Have you considered Stem Cell treatments for Chondromalacia Patella? Welcome to the stem cell center service for the state of KY! Many diseases and illnesses don't have to be as treacherous as once thought. There are potential cures and treatments available that are quite effective and very hopeful for Chondromalacia Patella If you are ready to consider adult stem cell treatment and adult stem cell therapy as an alternative for your medical disorder Chondromalacia Patella, then you are at the right place. Here at alternativetreatmentsfor.com we specialize in providing effective stem cells for Chondromalacia Patella in or near Alta, KY 51002. For immediate, free, and confidential assistance, download or .pdf file and call our helpline NOW!

Are you searching for a stem cell? Have you or someone you know been diagnosed with Chondromalacia Patella ? Welcome to the stem cell center service for the state of Wyoming! Many diseases and illnesses are more treatable than most people once thought. There are many potential cures - stem cells and treatments available that have proven to be quite effective and very hopeful for Chondromalacia Patella

If you are open to the idea of adult stem cell treatment and adult stem cell therapy as an alternative method of treatment for your medical disorder Chondromalacia Patella, then you have found the right place. Here at naturalcurefor.com we specialize in helping people heal by providing effective and stem cells for Chondromalacia Patella in or near Alta, Wyoming 51002. For immediate, free, and confidential assistance, download our .pdf file and call our helpline NOW!

We have successfully helped many people in Wyoming. We can help you attain real, effective, stem cells and alternative treatments for Chondromalacia Patella. Health improvements after our natural method of treatments have been used have shown terrific results in a very high percentage of cases. Every human being deserves to have good health and that is our desire to sincerely provide a network of resources available to help you or your loved one achieve better health. Don't let another day or week go by. Don't think that the pain or the Chondromalacia Patella you or a loved one have endured cannot be ended or put on a better more natural healing path to good health. Don't give up hope. We can help you recover, but you have to take the first step by contacting us now!

Alta, Wyoming - Stem cell for Chondromalacia Patella - We Can Provide Some Tremendous Hope if You Are Willing to Consider Adult Stem Cell Therapy and Treatments as Your Path Back To Good Health

Treating Chondromalacia Patella in a traditional medical manner is sometimes a long and grueling process that can offer less hope than you deserve. Additionally, many traditional medical treatments are riddled with drugs and medications that can sometimes cause even more harm to other parts of the body. Further risks of medication mixups, allergies, destruction of the immune system and the constant level of additional medical treatments that may be required, can sometimes weigh heavily on a patient and their chances of regaining a healthful way of life. Recovery can become difficult or almost impossible in some cases.

We offer an alternative treatment or a more stem cell process that centers around the idea of using your own adult stem cells as the basis of this natural treatment. In some areas of the country, traditional medicine and medical practices may not have acknowledged the benefits that stem cell treatments can bring to the healing process. Stem cell treatments may not be a standard course of medical treatment quite yet, but that may be a result of other political and/or profit motives. But rest assured that is all changing and changing quite rapidly as more and more success and overwhelming evidence indicates that adult stem cell therapy is a very successful and viable treatment process for Chondromalacia Patella.

Stem cell treatment is extremely effective and very safe. It is also very natural, ethical and a very effective way in assisting the body to heal naturally and wholesomely. It embodies the very idea of "healing" rather than simply medicating a symptom. The main idea of how adult stem cell treatments work are as follows...

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Stem Cell Therapy for Chondromalacia Patella in Alta Wyoming

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Epigenetics – Definition and More from the Free Merriam …

Posted: August 29, 2014 at 5:44 am

epigenetics noun e-p-j-ne-tiks

: the study of heritable changes in gene function that do not involve changes in DNA sequence

1942

: the study of how genes produce their effect on the phenotype of the organism

The study of the chemical modification of specific genes or gene-associated proteins of an organism. Epigenetic modifications define how genetic information is read and used by cells. Epigenetic modifications can be inherited and are influenced by environmental factors, some of which can induce epigenetic signaling that may contribute to biological processes such as aging. Methylation is the principal epigenetic modification of deoxyribonucleic acid (DNA) and of proteins called histones that package DNA into chromatin inside a cell. Epigenetic modifications influence gene expression and enable the differentiation of pluripotent stem cells (cells with the potential to become any of many different kinds of cells) into distinct cell types early in embryological development. The ability to control and alter stem cell differentiation through the manipulation of epigenetic modifications has profound implications for the treatment of conditions such as neurodegenerative disease.

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Epigenetics - Definition and More from the Free Merriam ...

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New tool aids stem cell engineering for medical research

Posted: August 29, 2014 at 5:43 am

PUBLIC RELEASE DATE:

28-Aug-2014

Contact: Robert Nellis newsbureau@mayo.edu 507-284-5005 Mayo Clinic

ROCHESTER, Minn. A Mayo Clinic researcher and his collaborators have developed an online analytic tool that will speed up and enhance the process of re-engineering cells for biomedical investigation. CellNet is a free-use Internet platform that uses network biology methods to aid stem cell engineering. Details of CellNet and its application to stem cell engineering are described in two back-to-back papers in the journal Cell.

"This free platform has a broad range of uses for all types of cell-based investigations and can potentially offer help to people working on all types of cancer," says Hu Li, Ph.D., investigator in the Mayo Clinic Center for Individualized Medicine and Department of Molecular Pharmacology & Experimental Therapeutics, and co-lead investigator in the two works. "CellNet will indicate how closely an engineered cell resembles the real counterpart and even suggests ways to adjust the engineering."

The network biology platform contains data on a wide range of cells and details on what is known about those cell types. Researchers say the platform can be applied to almost any study and allows users to refine the engineering process. In the long term, it should provide a reliable short cut to the early phases of drug development, individualized cancer therapies, and pharmacogenetics.

CellNet uses 21 cell types and tissues and data from 56 published human and mouse engineering studies as a basis for analyzing and predicting cell fate and corresponding engineering strategies. The platform also offers classification scores to determine differentiation and conversion of induced pluripotent stem cells. It reveals incomplete conversion of engineered microphages and hepatocytes. CellNet can be used for interrogation of cell fate following expression profiling, by classifying input by cell type, quantifying gene regulatory network status, and identifying aberrant regulators affecting the engineering process. All this is valuable in predicting success of engraftment of cancer tumors in mouse avatars for cancer and drug development research. CellNet can be accessed at cellnet.hms.harvard.edu.

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Co-lead authors with Dr. Li are Patrick Cahan, Ph.D., and Samantha Morris, Ph.D., of Boston Children's Hospital. The senior investigators are George Q. Daley, M.D., Ph.D., Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies and James Collins, Ph.D., Core Faculty member at the Wyss Institute and the William F. Warren Distinguished Professor at Boston University, co-senior investigator on one of the studies.

Investigators are supported in part by the National Institutes of Health, specifically, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Heart, Lung, and Blood Institute; the Children's Hospital Stem Cell Program; the Howard Hughes Medical Institute; Alex's Lemonade Stand Foundation; the Ellison Medical Foundation; the Doris Duke Medical Foundation; the Mayo Clinic Center for Individualized Medicine and the Mayo Clinic Center for Regenerative Medicine.

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New tool aids stem cell engineering for medical research

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Adult Stem Cell Public Lecture New York Manhattan Regenerative Medicine Medical Group

Posted: August 29, 2014 at 5:42 am

New York, California (PRWEB) August 28, 2014

The Manhattan Regenerative Medicine Medical Group announces a series of free public seminars on the use of adult stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief, and, Dr. Nia M. Smyrniotis, Medical Director.

The seminars will be held on Wednesday, September 3, 2014, at 2pm and 4pm at the City Limits Diner, at 135 Harvard Avenue, Stamford, CT 06902. Please RSVP at (917) 410-7391.

The Manhattan Regenerative Medicine Medical Group is an affiliate of the Miami Stem Cell Treatment Center, which abide by investigational protocols using adult adipose derived stem cells (ADSCs) which can be deployed to improve patients quality of life for a number of degenerative and chronic inflammatory conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (found within a cellular mixture called stromal vascular fraction (SVF). ADSCs are exceptionally abundant in adipose tissue. The adipose tissue is obtained from the patient during a 15 minute mini-liposuction performed under local anesthesia in the doctors office. SVF is a protein-rich solution containing mononuclear cell lines (predominantly adult autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important Growth Factors that facilitate the stem cell process and promote their activity.

ADSCs are the body's natural healing cells - they are recruited by chemical signals emitted by damaged tissues to repair and regenerate the bodys injured cells. The Manhattan Regenerative Medicine Medical Group and the Miami Stem Cell Treatment Center only use Adult Autologous Stem Cells from a person's own fat No embryonic stem cells are used. Current areas of study include: Emphysema, COPD, Asthma, Heart Failure, Parkinsons Disease, Stroke, Multiple Sclerosis, Lupus, Rheumatoid Arthritis, Crohns Disease, and degenerative orthopedic joint conditions. For more information, or if someone thinks they may be a candidate for one of the adult stem cell protocols offered by the Manhattan Regenerative Medicine Medical Group or Miami Stem Cell Treatment Center, they may contact Dr. Gionis or Dr. Nia directly at (917) 410-7391, or see a complete list of the Centers study areas at: http://www.MiamiStemCellsUSA.com or http://www.NYStemCellsUSA.com.

About Manhattan Regenerative Medicine Medical Group and the Miami Stem Cell Treatment Center: The Manhattan Regenerative Medicine Medical Group and The Miami Stem Cell Treatment Center is an affiliate of the Cell Surgical Network (CSN); they are located in Manhattan, NY; Miami, Boca Raton, and Orlando, Florida. We provide care for people suffering from diseases that may be alleviated by access to adult stem cell based regenerative treatment. We utilize a fat transfer surgical technology to isolate and implant the patients own stem cells from a small quantity of fat harvested by a mini-liposuction on the same day. The investigational protocols utilized by the Manhattan Regenerative Medicine Medical Group and the Miami Stem Cell Treatment Center have been reviewed and approved by an IRB (Institutional Review Board) which is registered with the U.S. Department of Health, Office of Human Research Protection; and the study is registered with Clinicaltrials.gov, a service of the U.S. National Institutes of Health (NIH). For more information visit our website: http://www.MiamiStemCellsUSA.com or http://www.NYStemCellsUSA.com.

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Adult Stem Cell Public Lecture New York Manhattan Regenerative Medicine Medical Group

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SVF Stem Cell Therapy For Neuropathy, MS, ALS, Knee Replacement, Shoulder Replacement – Video

Posted: August 29, 2014 at 5:41 am

SVF Stem Cell Therapy For Neuropathy, MS, ALS, Knee Replacement, Shoulder Replacement
http://www.innovationsmedical.com Call: 214.420.7970 Facebook: https://www.facebook.com/innovationsmedical Twitter: https://twitter.com/dallasdrj Instagram: ...

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Boy Scout Troop 286 Icebucket Challenge for the Scoutmaster – Video

Posted: August 29, 2014 at 5:41 am

Boy Scout Troop 286 Icebucket Challenge for the Scoutmaster
Ice Bucket Challenge Completed! With a whole lot of help from my Scouts! Donation went to the Midwest Stem Cell Therapy Center at KU Med in Kansas City. They do some terrific work there and...

By: Scott Medlock

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Boy Scout Troop 286 Icebucket Challenge for the Scoutmaster - Video

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ALS/Stem Cell Research Ice Bucket Challenge – Video

Posted: August 29, 2014 at 1:42 am

ALS/Stem Cell Research Ice Bucket Challenge
I tried to stay away from this but the religious right has forced me into it.

By: Graham Todd

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ALS/Stem Cell Research Ice Bucket Challenge - Video

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Stem Cell Research with Professor Francisco Figueiredo (Newcastle University) Q&A – Video

Posted: August 29, 2014 at 1:42 am

Stem Cell Research with Professor Francisco Figueiredo (Newcastle University) Q A
Durham CELLS (Centre for Ethics and Law in the Life Sciences) with the support of the Wellcome Trust organised a lecture with Professor Francisco Figueiredo ...

By: DurhamUniversity

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Stem Cell Research with Professor Francisco Figueiredo (Newcastle University) Q&A - Video