Page 2,033«..1020..2,0322,0332,0342,035..2,0402,050..»

'Holy grail' of organs grown in labs can end transplants

Posted: August 26, 2014 at 2:45 am

Scientists at Edinburgh University have for the first time been able to build a complete and functional organ in a living animal using cells created in a laboratory.

The breakthrough has been described as an important first step in developing a substitute for organ transplants which could eventually overcome problems with donor supplies and the use of immunosuppressive therapy.

Professor Clare Blackburn, from the Medical Research Council Centre for Regenerative Medicine at Edinburgh University, who led the team of scientists, said: "The ability to grow replacement organs from cells in the lab is one of the 'holy grails' in regenerative medicine.

"But the size and complexity of lab-grown organs has so far been limited.

"By directly reprogramming cells we've managed to produce an artificial cell type that, when transplanted, can form a fully organised and functional organ."

The technique, which produces a thymus, a vital immune system "nerve centre", has so far only been tested on mice.

It may be another 10 years before the treatment is proven to be effective and safe enough for human patients.

However, Professor Blackburn said: "This is an important first step towards the goal of generating a clinically useful artificial thymus in the lab."

The research is published in the journal Nature Cell Biology.

It reports that, while fragments of organs, including hearts, livers and even brains, have been grown from stem cells, no-one before has succeeded in producing a fully intact organ from cells created outside the body.

See the rest here:
'Holy grail' of organs grown in labs can end transplants

Posted in Regenerative Medicine | Comments Off on 'Holy grail' of organs grown in labs can end transplants

Rogue stem cell therapy operators charging thousands for ineffective treatments, researchers say

Posted: August 26, 2014 at 2:40 am

ABC Kellie van Meurs (3rd from R) died of a heart attack last month while receiving stem cell treatment in Moscow.

Rogue operators in Australia and overseas are charging thousands of dollars for ineffectual stem cell treatments, a leading stem cell research group has warned.

And Stem Cells Australia says there is a growing number of patients going overseas for stem cell treatments which are limited in Australia.

A loophole in the therapeutic goods legislation means that doctors are legally allowed to treat patients, both here and overseas, with their own stem cells even if that treatment is unsafe or has not been proven effective through clinical trials.

Stem Cells Australia believes that dozens of doctors in Australia offer the questionable treatments.

"They're selling treatment without any proof of benefit, and without any proof of safety," Associate Professor Megan Munsie, a stem cell biologist at the University of Melbourne, told 7.30.

Annie Leverington was diagnosed with multiple sclerosis in 2007.

She was once a talented flamenco dancer and worked as a court stenographer.

But in 2002 she noticed something was wrong when her fingers started to "drop" during long trials.

Then her feet started to go.

View post:
Rogue stem cell therapy operators charging thousands for ineffective treatments, researchers say

Posted in Stem Cell Therapy | Comments Off on Rogue stem cell therapy operators charging thousands for ineffective treatments, researchers say

New gene editing method corrects muscular dystrophy in mice

Posted: August 25, 2014 at 1:57 pm

Researchers at the University of Texas (UT) Southwestern Medical Center have developed a technique that corrects a mutation leading to Duchenne muscular dystrophy (DMD). The technique, called CRISPR/Cas9-mediated genome editing, removes the mutation entirely in mice, and could have far-reaching consequences in the treatment of muscular dystrophy in people.

According to the Centers for Disease Control, DMD appears in approximately one out of every 3,500 male births in the US (but rarely appears in girls). It usually strikes before the age of six, often confining patients to a wheelchair before adolescence, with death generally before age 25.

It is a severe form of muscular dystrophy caused by a mutation in a gene called dystrophin that leads to loss of function and strength, not only in voluntary muscles such as those in the arms and legs, but also (later) in the cardiovascular system. It has no cure and existing treatments focus on improving quality of life more so than on halting the progression of the disease.

Using CRISPR/Cas9-mediated genome editing to precisely remove the mutation in DNA responsible for DMD, the UT team found that the mouse's DNA repair mechanisms replace it with a normal copy of the gene. Unlike other approaches, such as exon skipping (causing cells to "skip" the mutation) and gene therapy (which delivers functional dystrophin via a harmless virus but retains the original dysfunctional copy of the gene), this new technique could potentially correct the problem at the source. In other words, it could permanently fix genetic defects, thereby promising completely functional DNA protein. This, in turn, could have a big impact on muscle regeneration over time.

"At the moment, we still need to overcome technical challenges, in particular to find better ways to deliver CRISPR/Cas9 to the target tissue and to scale up," says Dr. Eric Olson, director of the Hamon Center for Regenerative Science and Medicine at UT Southwestern. "But in the future we might be able to use this technique therapeutically, for example to directly target and correct the mutation in muscle stem cells and muscle fibers."

Mice injected with even just a subset of corrected cells showed progressive, widespread improvement over time, the research found. The hope is that the technique can one day be adapted for human treatment of muscular dystrophy.

"This is very important for possible clinical application of this approach in the future," Dr. Olson explains. "Skeletal muscle is the largest tissue in the human body and current gene therapy methods are only able to affect a portion of the muscle. If the corrected tissue can replace the diseased muscle, patients may get greater clinical benefit."

The research is described in a paper published in the journal Science.

Source: UT Southwestern

Go here to read the rest:

New gene editing method corrects muscular dystrophy in mice

Posted in Texas Stem Cells | Comments Off on New gene editing method corrects muscular dystrophy in mice

Stem Cells in GA – Georgia Bio

Posted: August 25, 2014 at 1:50 pm

During the 2006 Georgia General Assembly Session, Georgia Bio (GaBio) opposed passage of Senate Bill 596 that would have banned embyronic stem cell research and therapeutic cloning. The legislation was not approved. Subsequently Georgia Bio commissioned a poll of Georgia voters to assess their opinions on the issues. Results of the poll and other information related to the 2006 Legislative session are below.

During the 2007 General Assembly Session, GaBio opposed passage Senate Bill 148 as written. GaBio supported the efforts of SB 148 to establish a newborn umbilical cord blood bank and provide access to this tissue and blood for research and medical treatment; but opposed references in the bill to embryonic stem cell research as unnecessary to the bills purpose and in some cases unscientific. GaBio's press release on SB 148 is below.

During the 2009 General Assembly Session, GaBio opposed passage of Senate Bill 169. It would criminalize embryonic stem cell research and therapeutic cloning by defining an in vitro embryo as a human being, and prohibiting the creation of an embryo by therapeutic cloning or somatic cell nuclear transfer.

There are numerous scientific and medical organizations that fully support embryonic stem cell research. The area of stem cell research holds incredible promise for the developing treatments and cures for a host disease. GaBio has urged that all forms of stem cell research be pursued including adult stem cells, stem cells derived from post natal tissues and embryonic stem cells.

Georgia Bio, Stem Cell Research Position Statement, Adopted May 11, 2006, by the Board of Directors

Georgia Bio, Position Statement on SB 169, Adopted March 5, 2009

SB 169

Substitute SB 169

4/10/2007: GBP Urges Amending SB 148 To Remove Language Hostile to Stem Cell Research 9/30/2006: Poll: Significant Majority of Georgians Back Embryonic Stem Cell Research and Therapeutic Cloning 7/20/2006: Chambliss, Isakson Vote No on HR 810 7/14/2006: Governor Appoints Umbilical Cord Blood Research Commission 4/12/2006: GBP President Responds to Governor Perdues Order Creating a Cord Blood Research Commission 2/28/2006: Georgia Biomedical Partnership Responds To Georgia Senate Bills 596 and 537

Complete Press Packet (Includes Survey of Georgia Registered Voters Regarding Stem Cell Research issued by Ayres, McHenry & Associates, Inc.)

Read the original post:

Stem Cells in GA - Georgia Bio

Posted in Georgia Stem Cells | Comments Off on Stem Cells in GA – Georgia Bio

Core mechanism for root growth identified

Posted: August 25, 2014 at 1:50 pm

6 hours ago PLETHORA in root cells

PLETHORA proteins and plant hormone auxin orchestrate root growth together.

During plant growth, dividing cells in meristems must coordinate transitions from division to expansion and differentiation. Three distinct developmental zones are generated: the meristem, where the cell division takes place, and elongation and differentiation zones. At the same time, plants can rapidly adjust their direction of growth to adapt to environmental conditions.

In Arabidopsis thaliana roots, many aspects of zonation are controlled by the plant hormone auxin and auxin-induced PLETHORA transcription factors. Both show a graded distribution with a maximum near the root tip. In addition, auxin is also pivotal for tropic responses of the roots.

Ari Pekka Mhnen from the University of Helsinki, Finland, with his group and Dutch colleagues has found out with the help of experimentation and mathematical modelling how the two factors together regulate root growth.

"Cell division in the meristem is maintained by PLETHORA transcription factors. These proteins are solely transcribed in the stem cells, in a narrow region within the meristematic cells located in the tip of the root. So PLETHORA proteins are most abundant in the stem cells," Ari Pekka Mhnen, Research Fellow financed by the Academy of Finland says.

Outside the stem cells the amount of PLETHORA protein in the cells halves each time the cells divide. In the end there is so little PLETHORA left in the cells that they cannot stay in the dividing mode. This is when the cells start to elongate and differentiate.

Auxin is the factor taking care of many aspects of root growth. If there is enough PLETHORA in the root cells, auxin affects the rate of root cell division. If there is little or no PLETHORA in the cells, auxin regulates cell differentiation and elongation. In addition to this direct, rapid regulation, auxin also regulates cell division, expansion and differentiation indirectly and slowly by promoting PLETHORA transcription. This dual action of auxin keeps the structure and growth of the root very stable.

When PLETHORA levels gradually diminish starting from the root tip upwards, the cell division, elongation and differentiation zones are created. And this inner organisation stays even if the growth direction of the root changes.

"The gravity and other environmental factors can change the auxin content of the cells, and quite rapidly. This all affects the growth direction of the root. And of course it is important for the plant to maintain the organization while directing their roots there where water and nutrients most likely are to be found."

See original here:

Core mechanism for root growth identified

Posted in Delaware Stem Cells | Comments Off on Core mechanism for root growth identified

Our Physicians – Colorado Cell Surgical Network

Posted: August 25, 2014 at 1:50 pm

THE COLORADO CELL SURGICAL NETWORK TEAM KEN OLESZEK, M.D.

Dr. Ken Oleszek, MD is a Board Certified Physician and Owner/Medical Director of La Fontaine Aesthetics in Denver, Colorado. He dedicates his practice to utilizing high-tech medicine and laser procedures to optimize the health and appearance of his patients. In addition to stem cell research, Dr. Oleszek specializes in Phlebology (vein disease and the treatment of varicose veins), cutaneous laser treatments and minimally invasive aesthetic treatments including Fat transfer and office-based liposuction.

Dr. Oleszek is affiliated with the California Cell Surgical Network and the exciting ground breaking clinical research that may revolutionize the treatment of many medical diseases. He feels the accessibility of adipose tissue and the recent advances in extracting the stem cells from adipose tissue offers new and exciting potentials of stem cell treatment. At his Denver office, he will focus on studying stem cell treatments for degenerative orthopedic issues, such as knee,

Dr. Oleszek is on staff at Exempla Lutheran Medical Center, is a Fellow of The American Society of Lasers in Medicine and Surgery, and a member of The American College of Physicians, American College of Phlebology, American Venous Forum and the American Academy of Cosmetic Surgeons. After attending University of Colorado Medical School, he completed internship and residency in Internal Medicine at The University of New Mexico. Dr. Oleszek was born in upstate New York and moved to Colorado in his school years. With his training in Internal Medicine and degenerative diseases and experience with adipose tissue, Dr. Oleszek is excited to bridge these two areas of medicine with Stem Cell Treatments.

Being Medical Director at Sandhill Scientific Inc./Meditech International Inc., Dr. Oleszek was involved in the use of Low Level Laser Therapy as treatment for acute and chronic musculoskeletal diseases.

Dr. Greta McLaren graduated in the top of her class from the University of Colorado at Boulder with a B.A. in Biology and then earned her Medical Degree from and continues her affiliation as an Assistant Clinical Professor for the prestigious University of Colorado School of Medicine in Denver. She received her Board Certification in 1991 specializing in primary care, with a focus on Sports Medicine, Orthopedic injuries, and Dermatology. In addition, she was one of the first physicians in Colorado to train in the field of aesthetic laser surgery. As an expert in her field of Cosmetic Laser Procedures, Dr. McLaren has taught her fellow physicians throughout the United States for many years and continues to train resident physicians. She has also authored a book chapter on the subject of photodynamic therapies for treatment of precancerous lesions and various skin conditions. With her diverse and extensive training in dermatologic, orthopedic and degenerative diseases and her advanced training in liposculpting and fat transfer procedures, Dr. McLaren is privileged and excited to be involved with cutting edge fat derived stem cell therapies and applications in all of these fields.

Dr McLaren has been a teaching instructor in laser physics and aesthetic laser courses for physicians She has a particular interest in the research and development of regenerative medicine involving Stem cell harvesting from fat, and is honored to be an affiliate of the California Cell Surgical Network investigating the treatment of multiple medical disorders affecting the joints, lungs, heart, and nervous system.

Dr. McLarens practice is devoted exclusively to the health, vitality and well being of her patients Her sole commitment to anti-aging procedures, liposculpting, fat transfer and fat derived stem cell therapies gives her the ability to focus her energy and expertise on how best to lessen the effects of aging for men and women, and to give her patients an exceptional experience and outcome. She is committed to forging partnerships with her patients that focus on optimal, long-term health through education, empowerment, and personal responsibility

Dr. McLaren is the founder and medical director of a large anti-aging and laser practice in the Denver area. Her state of the art clinic offers the latest and most innovative techniques using platelet rich plasma and stem cells, in addition to Hi Definition liposculpting and all of the latest facets of anti-aging. In addition to her Stem Cell Practice, Dr. McLaren also hosts an extensive Laser procedure oriented website at http://www.skinsecretsmedspa.com.

CALIFORNIA

The rest is here:

Our Physicians - Colorado Cell Surgical Network

Posted in Colorado Stem Cells | Comments Off on Our Physicians – Colorado Cell Surgical Network

Stem Cell Therapy for Herpetic Whitlow in Indian Alaska

Posted: August 25, 2014 at 1:49 pm

Looking for help with Herpetic Whitlow in Indian? Listed below are doctors and medical centers in and near Indian Alaska.

If you are not looking for help with Herpetic Whitlow, check out the popular Herpetic Whitlow info on the right navigation area of the page. On the Herpetic Whitlow pages we include website links so you can check out Herpetic Whitlow online.

Are you searching for information about Herpetic Whitlow? Have you or someone you know been diagnosed with Herpetic Whitlow? Have you considered Stem Cell treatments for Herpetic Whitlow? Welcome to the stem cell center service for the state of KY! Many diseases and illnesses don't have to be as treacherous as once thought. There are potential cures and treatments available that are quite effective and very hopeful for Herpetic Whitlow If you are ready to consider adult stem cell treatment and adult stem cell therapy as an alternative for your medical disorder Herpetic Whitlow, then you are at the right place. Here at alternativetreatmentsfor.com we specialize in providing effective stem cells for Herpetic Whitlow in or near Indian, KY 99540. For immediate, free, and confidential assistance, download or .pdf file and call our helpline NOW!

Are you searching for a stem cell? Have you or someone you know been diagnosed with Herpetic Whitlow ? Welcome to the stem cell center service for the state of Alaska! Many diseases and illnesses are more treatable than most people once thought. There are many potential cures - stem cells and treatments available that have proven to be quite effective and very hopeful for Herpetic Whitlow

If you are open to the idea of adult stem cell treatment and adult stem cell therapy as an alternative method of treatment for your medical disorder Herpetic Whitlow, then you have found the right place. Here at naturalcurefor.com we specialize in helping people heal by providing effective and stem cells for Herpetic Whitlow in or near Indian, Alaska 99540. For immediate, free, and confidential assistance, download our .pdf file and call our helpline NOW!

We have successfully helped many people in Alaska. We can help you attain real, effective, stem cells and alternative treatments for Herpetic Whitlow. Health improvements after our natural method of treatments have been used have shown terrific results in a very high percentage of cases. Every human being deserves to have good health and that is our desire to sincerely provide a network of resources available to help you or your loved one achieve better health. Don't let another day or week go by. Don't think that the pain or the Herpetic Whitlow you or a loved one have endured cannot be ended or put on a better more natural healing path to good health. Don't give up hope. We can help you recover, but you have to take the first step by contacting us now!

Indian, Alaska - Stem cell for Herpetic Whitlow - We Can Provide Some Tremendous Hope if You Are Willing to Consider Adult Stem Cell Therapy and Treatments as Your Path Back To Good Health

Treating Herpetic Whitlow in a traditional medical manner is sometimes a long and grueling process that can offer less hope than you deserve. Additionally, many traditional medical treatments are riddled with drugs and medications that can sometimes cause even more harm to other parts of the body. Further risks of medication mixups, allergies, destruction of the immune system and the constant level of additional medical treatments that may be required, can sometimes weigh heavily on a patient and their chances of regaining a healthful way of life. Recovery can become difficult or almost impossible in some cases.

We offer an alternative treatment or a more stem cell process that centers around the idea of using your own adult stem cells as the basis of this natural treatment. In some areas of the country, traditional medicine and medical practices may not have acknowledged the benefits that stem cell treatments can bring to the healing process. Stem cell treatments may not be a standard course of medical treatment quite yet, but that may be a result of other political and/or profit motives. But rest assured that is all changing and changing quite rapidly as more and more success and overwhelming evidence indicates that adult stem cell therapy is a very successful and viable treatment process for Herpetic Whitlow.

Stem cell treatment is extremely effective and very safe. It is also very natural, ethical and a very effective way in assisting the body to heal naturally and wholesomely. It embodies the very idea of "healing" rather than simply medicating a symptom. The main idea of how adult stem cell treatments work are as follows...

Visit link:

Stem Cell Therapy for Herpetic Whitlow in Indian Alaska

Posted in Alaska Stem Cells | Comments Off on Stem Cell Therapy for Herpetic Whitlow in Indian Alaska

Catholic Leaders Put A Chill On ALS Ice Bucket Challenge – Video

Posted: August 25, 2014 at 11:40 am


Catholic Leaders Put A Chill On ALS Ice Bucket Challenge
Leaders are worried about embryonic stem cell research using aborted human fetuses. CBS 2 #39;s Lou Young reports. Official Site: http://newyork.cbslocal.com/ YouTube: http://www.youtube.com/user/CBS...

By: CBS New York

More:
Catholic Leaders Put A Chill On ALS Ice Bucket Challenge - Video

Posted in Stem Cell Research | Comments Off on Catholic Leaders Put A Chill On ALS Ice Bucket Challenge – Video

ALS Ice Bucket Challenge – Mallory Ranem – Video

Posted: August 25, 2014 at 11:40 am


ALS Ice Bucket Challenge - Mallory Ranem
I was nominated by Carley Biniek and Jim Ranem; I nominate Tori Conners, Jessie Conners, and Brianna Sundgaard. In light of the ALSA #39;s policy on Embryonic Stem Cell research, I #39;ll be making...

By: Dustin Ranem

Follow this link:
ALS Ice Bucket Challenge - Mallory Ranem - Video

Posted in Stem Cell Research | Comments Off on ALS Ice Bucket Challenge – Mallory Ranem – Video

Amazing pensioner helps save 264 lives in 30 countries on four continents

Posted: August 24, 2014 at 2:45 pm

At the age of 70, many people are retired but Glenn Abbassi is still dashing round the world doing one of the most important jobs ever.

As a volunteer courier for bone marrow register Anthony Nolan, its her mission to travel thousands of miles transporting vital stem cells for seriously ill transplant patients.

So far, during seven years in her role, she has helped to save the lives of 264 people. She has travelled to four continents and more than 30 countries. She even spent last Christmas away from her family in China.

Speaking yesterday in support of a new Anthony Nolan campaign, she said: I wouldnt change it for the world. Every trip I embark on is as important as the next one.

Glenn, a former NHS complaints manager, explained how donated cells have to be with the recipient within 72 hours.

Getting back in time is a matter of life or death, she said.

The cells are used to treat a range of conditions, including cancer and blood disorders.

Glenns role is particularly poignant as her first husband Peter Davies was diagnosed with the blood disorder aplastic anaemia in 1977. He died three years later aged just 43.

She met her current husband Eddie, 68, a retired air conditioning engineer, a few years later when he flew to Britain from his homeland in Iran to donate his bone marrow to his brother.

They fell in love when Eddie lodged with her while his brother recovered.

More:
Amazing pensioner helps save 264 lives in 30 countries on four continents

Posted in Stem Cells | Comments Off on Amazing pensioner helps save 264 lives in 30 countries on four continents

Page 2,033«..1020..2,0322,0332,0342,035..2,0402,050..»