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Special birthday present: Stem cell donor returns to Goltry

Posted: June 27, 2014 at 7:51 am

GOLTRY, Okla. A Goltry-area woman is back on Oklahoma soil after traveling to Milwaukee to give her brother a special birthday present.

Jeni Sumner was the only match among family members tested to donate stem cells to her younger brother, who was diagnosed with acute myelogenous leukemia last year.

Ed Dees cancer went into remission last October but returned earlier this year. Sumner said Dees doctors felt a stem cell transplant would be the best treatment.

Sumner spoke by phone about the events of the past week, as she prepared to return to Oklahoma on Thursday morning.

The transplant began at 2:07 p.m. Tuesday Dees birthday and took about an hour, she said.

We had a little birthday party for him and then he got my present, Sumner said.

Prior to the transplant, Dee went through chemotherapy and had a conditioning treatment, which Sumner said entailed the doctors wiping out his immune system and blood levels.

Sumner had to give herself injections over four days to make her bone marrow produce more stem cells and push them into her blood.

Those went really well, she said.

The stem cell retrieval process was on Monday.

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My Regeneration

Posted: June 27, 2014 at 7:50 am

What cantodaysgenerationhope for fromregenerativemedicine?

Its a frontier for business, the medical profession and society. Regenerative medicine aims to shift the focus from palliative care to the development of treatments that address diabetes, Parkinsons disease, stroke and heart disease. The hope is that well live longer, healthier lives and have greater independence in old age, thereby reducing the burden on healthcare systems. Given global population demographics, this is essential: according to the World Health Organisation by 2050 there will two billion people aged 60 years and over.

Regenerative medicine already has a rich history of achievement, as illustrated in the timeline. Today, researchers and doctors are making inroads via the use of cell therapies, tissue scaffolds and growth factors; and new technologies, such as 4D bioprinting, all promising to dramatically increase the speed of progress. A number of companies present at BIO 2014, including AntiCancer Inc., RegenLab, Sanford Health, Merck, Lilly and Janssen Pharmaceutical Companies of Johnson & Johnson are pioneering regenerative medicine projects.

To get a better grasp of the achievements, challenges and potential of regenerative medicine, we talked to four of the worlds leading experts in the field. Heres what they told us.

Aubrey de Grey is the biomedical gerontologist who founded SENS (Strategies for Engineered Negligible Senescence) Research Foundation. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.

What do you think are the greatest achievements in regenerative medicine so far?

I think it would be difficult to argue against two breakthroughs published in 2006 and 2008 respectively: induced pluripotent stem cells (Shinya Yamanaka) and decellularisation of organs (Doris Taylor). Both these techniques proved to be quite easy to reproduce in other laboratories, so their potential is moving towards the clinic far more quickly than usual.

What are the biggest challenges in this research and development space? It remains highly challenging to generate sufficiently pure stem cells of a desired type to ensure safety and efficacy. Also, while the decellularisation approach is a great breakthrough, we still need to get better at reseeding a scaffold with desired cells. As a solution to the vascularisation issue that has stalled solid-organ tissue engineering for so long, a promising alternative to decellularisation is organ printing, but it still faces daunting obstacles in terms of creating sufficiently tough blood vessels.

Where do you think the field will be in 10 years? I think regenerative medicine will be at the heart of medicine for the elderly by 2024, having reached a level of sophistication that allows the genuine cure of relatively simple age-related conditions such as Parkinsons Disease and the alleviation of a wide range of aspects of age-related ill-health.

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My Regeneration

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AKC Canine Health Foundation Funds Landmark Clinical Trial on Regenerative Medicine Treatment for Dogs

Posted: June 27, 2014 at 7:50 am

Raleigh, NC (PRWEB) June 26, 2014

The AKC Canine Health Foundation (CHF) is pleased to announce the funding of a landmark clinical trial to establish the evidence-based use of regenerative medicine to treat tendon injury in dogs.

Funded as part of CHFs Canine Athlete Initiative which seeks to fund research and provide education for dog owners in the rapidly expanding field of canine sports, this newly funded collaborative grant will inform the veterinary community in the use of safe and effective regenerative medicine techniques.

According to Dr. Shila Nordone, CHF Chief Scientific Officer, Regenerative medicine is a rapidly developing field with the potential to transform the treatment of canine and possibly human disease. Nordone goes on to say, Because current regenerative medicine products and techniques vary widely and success stories are anecdotal at best, CHF is committed to funding independent studies that support the evidence-based practice of regenerative medicine.

Principal Investigators Dr. Jennifer Barrett, MS, PhD, DVM, DACVS, DACVSMR; Dr. Sherman Canapp, DVM, MS, CCRT, DACVS, DACVSMR; and Dr. Victor M. Ibrahim, MD, FAAPMR, will conduct the first blinded, placebo-controlled clinical trial evaluating the effectiveness of platelet-rich plasma and stem cells on the most common sporting injury in dogs: supraspinatus tendonopathy, a shoulder injury that is similar to rotator cuff injury in humans.

In dogs, tendon injuries often progress undiagnosed and result in chronic lameness and pain. If left untreated, scar tissue may form, reducing the function of the joint and surrounding muscle tissue. Through this grant, a collaborative group of veterinary sports medicine specialists across multiple disciplines will determine if regenerative mediScine therapies promote healing through tissue regeneration and reduced scarring.

As dogs are living longer and participating in more sporting events, CHF is committed to being on the leading-edge of novel therapies that will help all dogs stay Fit For Sport, Fit For Life.

CHF is a non-profit organization dedicated to funding research to prevent, treat, and cure canine disease. Visit CHF online at http://www.akcchf.org for more information about the Foundation. Like CHF on Facebook, follow CHF on Twitter @CanineHealthFnd, or connect with CHF on LinkedIn.

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AKC Canine Health Foundation Funds Landmark Clinical Trial on Regenerative Medicine Treatment for Dogs

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2014 World Stem Cell Summit presented by GPI, Mary Ann Liebert, Inc, and GEN

Posted: June 27, 2014 at 7:46 am

PUBLIC RELEASE DATE:

25-Jun-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, June 25, 2014Mary Ann Liebert, Inc., publishers website and Genetic Engineering & Biotechnology News (GEN) are proud to announce that they will again serve as joint platinum media sponsors of the Genetics Policy Institute 2014 World Stem Cell Summit that will take place at the Marriott River Center, December 4-6, 2014 in San Antonio, Texas.

In a new collaborative effort in 2014, Mary Ann Liebert, Inc. will also organize a World Stem Cell Summit panel, comprised of leading editors from their peer-reviewed journals intersecting the field to predict the most innovative translational research that will impact regenerative medicine in the next five years.

Mary Ann Liebert, Inc. will also publish the 2014 World Stem Cell Report as a special supplement to the peer-reviewed journal Stem Cells and Development. Dr. Graham Parker, Editor-in-Chief of Stem Cells and Development, and Bernard Siegel, Executive Director of Genetics Policy Institute (GPI), will serve as Co-Editors-in-Chief of the Report, joined by Rosario Isasi (McGill University) as Managing Editor. The World Stem Cell Report will be made available to all subscribers of Stem Cells and Development and attendees of the World Stem Cell Summit. It will also be available free online in 106 developing countries, courtesy of the Publisher, to facilitate global stem cell research.

"We are very pleased to expand our collaboration with Mary Ann Liebert, Inc., and GEN," says Bernard Siegel, Founder and Co-chair of the Summit. "The commitment by those prestigious publishers to journalistic integrity and scientific knowledge and education matches our enthusiasm to advance the field of stem cells and regenerative medicine for the betterment of humanity. We look forward to working with Graham Parker and the skilled editorial team at Stem Cells and Development to publish our annual Report. We are especially excited to have the expertise of the Liebert editors engaged on the program at the World Stem Cell Summit."

"The World Stem Cell Summit is unequivocally a paramount meeting that brings together the leaders in the field from academia, industry, and business, thereby ensuring the advancement of collaborative opportunities," says Mary Ann Liebert, publisher & CEO of both Stem Cells and Development and GEN. "Bernie Siegel and GPI also recognize the importance of public advocacy at this most important international conference. Mary Ann Liebert, Inc. is delighted to expand our own collaboration with Bernie Siegel and GPI and to publish the 2014 Report.

GEN Editor-in-Chief John Sterling stated, "The World Stem Cell Summit is the critical global meeting, providing the best opportunity for the GEN community to participate in the world of regenerative medicine. Our platinum media sponsorship allows GEN readers and advertisers to have a front row seat to listen and learn from the top experts on the very dynamic and expertly conceptualized Summit platform."

The Summit program delivers on the "big picture," featuring over 200 prominent scientists, business leaders, regulators, policy-makers, advocates, economic development officers, experts in law and ethics, and visionary gurus who will discuss the latest scientific discoveries, business models, legal and regulatory solutions, and best practices. The Summit is expected to attract attendees from more than 40 nations.

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South Reno Veterinary Hospital is Prolonging Pet Quality of Life with Stem Cell Therapy and the Ability to Bank Cells …

Posted: June 27, 2014 at 7:45 am

Poway, CA (PRWEB) June 27, 2014

South Reno Veterinary Hospital and Mathew Schmitt, VMD have recently discovered the secret to prolonging a pets quality of life with the use of stem cell therapy, and the ability to bank stem cells for the future care of a pet. Dr. Schmitt and South Reno Veterinary Hospital offer stem cell therapy and stem cell banking through Vet-Stem, Inc. for small animal osteoarthritis and partial ligament tears.

As many as 65% of dogs between the ages of 7 and 11 years old will be inflicted with some degree of arthritis. For certain specific breeds the percentage is as high as 70, such as Labrador Retrievers. Barley, a Labrador mix, was treated using cells from a sample of his own fat, and some stem cells are also stored (or banked) with Vet-Stem just in case he needs future treatment with Dr. Schmitt. Those banked stem cells do not have to be used for the same use as they were originally used for either. For example, if a pet has stem cell therapy initially for osteoarthritis pain and inflammation, the banked stem cells can be used years later for an acute injury.

After rupturing the canine cruciate ligaments in both of his stifles, or hind knees, Barleys pain was managed by medication but then medication was finally not enough and he was facing the possibility of surgery. Dr. Schmitt reported shifting lameness in Barleys hind end, which was a sign of severe discomfort. Barleys owner did not want to put him through surgery on both knees. Instead, Barleys owner elected for stem cell therapy.

I fully believe stem cell therapy has significantly prolonged Barleys quality of life and I am so glad I found out about the therapy when he was injured at six years old. He just turned 13 and his legs are still doing well. It truly is a miracle of science and I tell all my friends about it, said Barleys mom.

Vet-Stem, along with countless research and academic institutions, is working to support additional uses for stem cells which may include treatment for liver disease, kidney disease, auto-immune disorders, and inflammatory bowel disease in animals. These uses for stem cells are in the early stages of development and may provide additional value to the ability to bank stem cells to ensure a pets quality of life into the future.

About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine, visit http://www.vet-stem.com/ or call 858-748-2004.

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South Reno Veterinary Hospital is Prolonging Pet Quality of Life with Stem Cell Therapy and the Ability to Bank Cells ...

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Scripps Research Institute Scientists Find Potential New Use for Cancer Drug in Gene Therapy for Blood Disorders

Posted: June 27, 2014 at 7:45 am

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Newswise LA JOLLA, CA June 26, 2014 Scientists working to make gene therapy a reality have solved a major hurdle: how to bypass a blood stem cells natural defenses and efficiently insert disease-fighting genes into the cells genome.

In a new study led by Associate Professor Bruce Torbett at The Scripps Research Institute (TSRI), a team of researchers report that the drug rapamycin, which is commonly used to slow cancer growth and prevent organ rejection, enables delivery of a therapeutic dose of genes to blood stem cells while preserving stem cell function.

These findings, published recently online ahead of print by the journal Blood, could lead to more effective and affordable long-term treatments for blood cell disorders in which mutations in the DNA cause abnormal cell functions, such as in leukemia and sickle cell anemia.

Improving Gene Delivery to Blood Stem Cells

Viruses infect the body by inserting their own genetic material into human cells. In gene therapy, however, scientists have developed gutted viruses, such as the human immunodeficiency virus (HIV), to produce what are called viral vectors. Viral vectors carry therapeutic genes into cells without causing viral disease. Torbett and other scientists have shown that HIV vectors can deliver genes to blood stem cells.

For a disease such as leukemia or leukodystrophy, where mutations in the DNA cause abnormal cell function, efficiently targeting the stem cells that produce these blood cells could be a successful approach to halting the disease and prompting the body to produce healthy blood cells.

If you produce a genetic modification in your blood stem cells when you are five years old, these changes are lifelong, said Torbett. Furthermore, the gene-modified stem cells can develop into many types of cells that travel throughout the body to provide therapeutic effects.

However, because cells have adapted defense mechanisms to overcome disease-causing viruses, engineered viral vectors can be prevented from efficiently delivering genes. Torbett said that when scientists extract blood stem cells from the body for gene therapy, HIV viral vectors are usually able to deliver genes to only 30 to 40 percent of them. For leukemia, leukodystrophy or genetic diseases where treatment requires a reasonable number of healthy cells coming from stem cells, this number may be too low for therapeutic purposes.

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Easecox Marvel Anti-Aging Skin Care Program – Video

Posted: June 26, 2014 at 8:47 pm


Easecox Marvel Anti-Aging Skin Care Program
Anti-Aging Program The anti-aging program is a combination of plant stem cells derived via state-of-the-art bio-chemical technology and a high mountain mineral formula from German homeopathy...

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Stem cells used in promising MS study – Video

Posted: June 26, 2014 at 8:47 pm


Stem cells used in promising MS study
There is a promising study for people with a progressive form of multiple sclerosis.

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Dr. Nathan Newman + Stem Cells = Jeunesse – Video

Posted: June 26, 2014 at 8:47 pm


Dr. Nathan Newman + Stem Cells = Jeunesse
Dr. Nathan Newman has innovated the Stem Cell Lift to restore your youth naturally using stem cells from your own body. Be successful with Jeunesse... Learn more: http://bit.ly/1l1DvBU.

By: Le Marshe

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PRP and Stem Cell Treatments For Hair Regrowth : TV5 News – Video

Posted: June 26, 2014 at 8:47 pm


PRP and Stem Cell Treatments For Hair Regrowth : TV5 News
Subscribe to TV5 News Channel: http://goo.gl/NHJD9 Like us on Facebook: http://www.facebook.com/tv5newschannel Follow us on Twitter: https://twitter.co...

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