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Dr. Omar Gonzalez presents Best Stem Cell Therapy in Mexico: Integrative Medicine Clinic – Video

Posted: June 23, 2014 at 5:43 pm


Dr. Omar Gonzalez presents Best Stem Cell Therapy in Mexico: Integrative Medicine Clinic
http://www.placidway.com/profile/705/ - Watch this Video as Dr.Omar Gonzalez, MD, specialist in Stem Cell Therapy, Integrative Medicine and Chronic Diseases, presents his new clinic located...

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Dr. Omar Gonzalez presents Best Stem Cell Therapy in Mexico: Integrative Medicine Clinic - Video

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Dr Sharad Kapoor explaining the Advances of Stem Cells – Video

Posted: June 23, 2014 at 9:46 am


Dr Sharad Kapoor explaining the Advances of Stem Cells
Dr Sharad Kapoor #39;s detailed explanation on the Advances of Stem Cells Stemade Biotech.

By: StemadeBiotech

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Dr Sharad Kapoor explaining the Advances of Stem Cells - Video

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Supported For Stem Cell Research – Video

Posted: June 23, 2014 at 9:46 am


Supported For Stem Cell Research

By: chia mun hong

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Supported For Stem Cell Research - Video

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Dr Bharat Chetal on Stem Cell Research – Video

Posted: June 23, 2014 at 9:43 am


Dr Bharat Chetal on Stem Cell Research
Dr Bharat Chetal providing details on Stem Cell Research.

By: StemadeBiotech

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Dr Bharat Chetal on Stem Cell Research - Video

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Windows bug-testing software cracks stem cell programs

Posted: June 22, 2014 at 5:08 pm

SOFTWARE used to keep bugs out of Microsoft Windows programs has begun shedding light on one of the big questions in modern science: how stem cells decide what type of tissue to become.

Not only do the results reveal that cellular decision-making is nowhere near as complicated as expected, they also raise hopes that the software could become a key tool in regenerative medicine.

"It is a sign of the convergence between carbon and silicon-based life," says Chris Mason, a regenerative medicine specialist at University College London. "World-class stem cell scientists and a world-class computer company have found common ground. It is work at such interfaces that brings the big breakthroughs."

Stem cells are the putty from which all tissues of the body are made. That means they have the potential to repair damaged tissue and even grow into new organs.

Embryonic stem cells hold particular promise as they can either renew themselves indefinitely or differentiate into any kind of cell in the body a property known as pluripotency.

The process that sets a stem cell on the path to either self-renewal or differentiation was thought to be a highly complex web of genetic and environmental interactions. That web is known as the interactome.

Embryonic stem cells are currently being trialled as a way to restore vision and treat spinal injury. But these trials, and others in the pipeline, are hampered by the fact that no one really knows what determines the fate of any particular stem cell. Today's techniques for making a stem cell differentiate into a certain tissues are hit-and-miss, says Mason.

What's needed is a more deterministic, reliable method, says Sara-Jane Dunn, a computational biologist at Microsoft Research in Cambridge. One approach is to frame the problem in the language of computation. The genetic and environmental cues that determine the cell's fate can be thought of as inputs, with the cell itself as the processor, Dunn says.

Stem cells' capacity to renew themselves is the simplest of the two possible paths out of the pluripotent state. To find the program behind this, Dunn, along with stem cell scientists Graziano Martello at the University of Padua in Italy, and Austin Smith at the University of Cambridge, tried to isolate the genetic and environmental processes at work in mouse embryonic stem cells.

They used a technique pioneered at Smith's lab that uses cultures of various inhibitory proteins to keep embryonic stem cells continually renewing themselves rather than differentiating into other cells. The team immersed the stem cells in four different types of these cultures and analysed which genes they expressed in which environment, and to what extent.

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Windows bug-testing software cracks stem cell programs

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Lasers and Stem Cells Regrowing Teeth

Posted: June 22, 2014 at 5:08 pm

Stem cells are the future of healthcare for the human race, as we've studied them more we've found out all the different ways that they could be used to take care of many of the problems facing people today, from baldness to Alzheimer's research, they've become the miracle cure that society has wanted to badly for so many years. (christianitytoday) The biggest problem people have had with stem cell treatment is that when it began the primary source of stem cells was via embryonic stem cells, this put the majority of people off the process as they weren't willing to support aborted embryos in order to progress medically. (frc) With the advancement in the process and the ability to generate stem cells from adult tissue the battle over the ethics of using said cells to treat the many illnesses and injuries that have embattled the human race for ages, making it more palatable for those who were once torn over the research. (childrenshospital) As the debate rages on over the benefits and risks of stem cell treatment the benefits keep growing and the negatives seem to be slowly passing by the wayside, as a result using stem cells to take care of our ailments is gaining steam and with any luck it'll change everything for the better. (nih)

One of the most common medical problems that has faced people since the begging of time is dental work, while we've made progress in this field we're still somewhat archaic in it as well, relying on drills and pliers to repair damage that has accrued over time. (acedentalresource) There have been tests in order to regrow teeth and surrounding tissue using stem cells for some time now, with positive results it's seemed that stem cell treatment would be the next step in taking care of our teeth and we would finally get past the need for dentures or implants, although the question is how long that may take. (reuters) Last year the move to regrow teeth saw an advancement through the use of stem cells that were derived from urine, not quite the process people want to envision the process happening but it seemed like the most likely way to avoid painful implants or terrible fitting dentures. (nydailynews) A new evolution seems to be on the horizon now using low level lasers and stem cells to regenerate teeth instead of having to replace them, this is a huge development and as someone with dental concerns myself and a severe phobia of dentists, I'm looking forward to the future on this one. (iflscience)

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Lasers and Stem Cells Regrowing Teeth

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From stem cells to physics fraudulent science results are plenty but hard to find

Posted: June 22, 2014 at 5:08 pm

Haruko Obokata at the Riken Center for Developmental Biology in Kobe, Japan, claimed to have discovered an easy and straightforward way to reprogramme adult cells to become stem cells.

Soon after publication in "Nature" in January, problems and accusations arose with fellow scientists saying they could not replicate the results. Obokata was accused of having plagiarized passages of text and of having used duplicated images.

The Riken Research Center urged her to retract the papers. Obokata refused - until this week.

No surprise

"Couldn't we see that this news would follow when we first read the news of the discovery?" a reader writes in a forum at German news magazine "Spiegel Online."

Indeed: the results were too good to be true.

Especially where stem cells are concerned, sudden miracles tend to fall flat when they are checked rigorously by peers.

Cloning specialist Hwang Woo-suk fabricated results

The story of South Korean veterinarian Hwang Woo-suk is similar. In 2006 he claimed to have created human embryonic stem cells by cloning, but was later dismissed from Seoul National University when it was revealed that he had faked his results.

And in the field of physics, a German researcher called Jan Hendrik Schn became prominent with his groundbreaking experiments on semiconductors, until 2002 when it turned out his results were a fraud.

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From stem cells to physics fraudulent science results are plenty but hard to find

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Stem-cell advances may quell ethics debate

Posted: June 22, 2014 at 5:08 pm

LOUISVILLE, Ky. -- Robert Waddell says he's glad the stem cells that healed him came from "a guy who was 50 years old" and not a human embryo.

As a Catholic, Waddell opposes the destruction of embryos and didn't want to rely on embryonic stem cells to cure his kidney disease. But he avoided this moral dilemma by getting bone marrow stem cells from a friend who donated a kidney as part of a University of Louisville study.

"It has nothing to do with embryonic stem cells," said Waddell, a 47-year-old father of four. "That made it a lot easier."

Recent strides in stem-cell research show adult stem cells to be ever-more-promising, many scientists say, quelling the controversy steeped in faith and science that has long surrounded embryonic stem cells.

In fact, University of Louisville researcher Scott Whittemore said the debate is almost moot.

"Realistically, (many scientists don't use) the types of stem cells that are so problematic anymore," he said, adding that adult stem cells can now be reprogrammed to behave like embryonic stem cells. "The field has moved so fast."

In addition to these genetically reprogrammed adult cells - known as induced pluripotent stem cells or iPS cells - scientists are on the cusp of being able to turn one type of cell into another in the body without using stem cells at all. They shared some of the latest research last week at the annual International Society for Stem Cell Research in Vancouver.

"IPS cells overcame the main ethical issues," namely the use of embryos some Americans consider sacred human life, said Brett Spear, a professor of microbiology, immunology and molecular genetics at the University of Kentucky who uses iPS cells to model liver disease.

But other scientists argue that embryonic stem cell research remains important.

Dr. George Daley, director of the stem cell transplant program at Boston Children's Hospital and past president of the research society, said embryonic cells are a tool in the search for cures.

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Umbilical cord blood helps to save lives

Posted: June 22, 2014 at 5:08 pm

SOUTH BEND, Ind.--- In the 1970's, researchers discovered that a newborn's umbilical cord blood contained special stem cells that could help fight certain diseases.

More than 30 years later doctors are still experimenting and learning more about the use of cord blood.

Amanda Canale doesn't take time with her daughter and niece for granted.

She's just happy to feel good.

"I've been in the hospital, and I've been sick my whole life," said Amanda.

Amanda was born with a rare blood disorder that required daily shots.

"Basically, I have no white blood cells. I have no immune system at all," said Amanda

At 23 she developed Leukemia and was given two weeks to live.

She desperately needed a Bone Marrow Transplant, but family members weren't matches.

Her doctor suggested an Umbilical Cord Blood Transplant.

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Umbilical cord blood helps to save lives

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Gene editing tool can write HIV out of the picture

Posted: June 22, 2014 at 5:05 pm

Take a hot new method that's opened up a new era of genetic engineering, apply it to the wonder stem cells that in 2012 won their discoverer a Nobel prize, and you might just have a tool to cure HIV infection.

That's the hope of researchers led by Yuet Kan of the University of California, San Francisco and they have proved the basic principle, altering the genome of induced pluripotent stem cells (iPSCs) to give them a rare natural mutation that allows some people to resist HIV.

Kan's work relies on "genome editing" snipping out a particular DNA sequence and replacing it with another. It's much more precise than traditional forms of genetic engineering, in which sequences are added to the genome at random locations.

To alter the stem cells, Kan's team turned to the CRISPR-Cas9 system, a super-efficient method of genome editing based on an ancient bacterial "immune system". In bacteria, the system takes fragments of DNA from invading viruses and splices them into the cell's own DNA, where they act like "wanted" posters, allowing the viruses to be recognised and attacked in future.

About 1 per cent of people of European descent are resistant to HIV, because they carry two copies of a mutation in the gene for a protein called CCR5. The virus must lock onto this protein before it can invade white blood cells, and the mutations prevent it from doing so.

Using a bone marrow transplant from a naturally HIV-resistant person, Timothy Ray Brown was famously "cured" of HIV infection. Kan's goal is to achieve the same result without the need to find compatible HIV-resistant bone marrow donors who are in vanishingly short supply.

It's fairly easy to make iPSCs from a person's cells, which then have the potential to grow into any type of cell in the body. So if iPSCs could be given two copies of the protective mutation, it should be possible to make personalised versions of the therapy that cleared HIV from Brown's body. Kan's team has now shown that CRISPR-Cas9 can efficiently make the necessary genome edit. As expected, white blood cells grown from these altered stem cells were resistant to HIV upon testing.

"It's a really fantastic application of the tool," says Philip Gregory, chief scientific officer with Sangamo BioSciences of Richmond, California. However, he warns that there is a long way to go before it can be turned into a practical therapy.

Kan has not yet grown the iPSCs into the specific type of white blood cells called CD4+ T cells that are ravaged by HIV. What he instead plans to do is turn the iPSCs into blood-forming stem cells, which when transplanted into the body would give rise to all of the cell types found in the blood. "One of the problems is converting iPSCs into a type of cell that is transplantable," says Kan. "It is a big hurdle."

Regulators will also need to be convinced that cells that have been subjected to extensive genetic manipulation both to create the iPSCs, and to give them the protective mutation are safe.

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Gene editing tool can write HIV out of the picture

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