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Boy getting a chance for a better life

Posted: June 12, 2014 at 11:43 am

An Okotoks boy may not understand his community is helping to give him a better life this weekend, but there is a good chance he will be smiling anyway.

At four years old, Ryker Menzies communicates through a series of sounds, suffers from frequent muscle spasms, is in a wheelchair because hes unable to walk or sit on his own and is constantly on painkillers.

This has been Rykers reality since infancy due to a severe case of cerebral palsy, and his parents Tiffany Boyd and Jamie Menzies are hopeful stem cell therapy treatment in Panama City will improve his muscle movement, vision and speech.

Unfortunately, they havent been able to afford the procedure living on one income while Boyd cares for Ryker.

To help pay for the $15,600 treatment, the couple is organizing a mini-market at the Foothills Centennial Centre on June 14 from 11 a.m. to 4 p.m. and inviting the community to check out an abundance of second-hand items and products from home-based and privately-owned businesses for an entry fee of $2.

Money will also be raised through a food vendor, numerous raffle tickets for prizes including vacations and toys, and items donated by residents. Okotoks singer Emily Gryba will perform at the event.

Ive been getting a lot of calls from people donating stuff to the market to sell there, as well as a few online donations, said Boyd. We will just set up about five tables and have family run them. The proceeds will go to Ryker.

Boyd said she is ecstatic at the amount of community support for Rykers stem cell treatment. An online fund she established called Raise for Rykstar collected $1,300, with another $2,000 donated by family, friends and community members.

The feedback has been fantastic, she said. Were already at $3,500.

As the family gets closer to reaching their financial goal, Boyd is eager to book an appointment to give Ryker the best life possible. She said she was told they will have an appointment within a month or two of making the call.

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Boy getting a chance for a better life

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Beverly Hills Orthopedic Institute Now Offering Revolutionary Stem Cell Procedures for Hip Arthritis to Avoid Joint …

Posted: June 12, 2014 at 11:43 am

Beverly HIlls, California (PRWEB) June 09, 2014

The top stem cell doctor in Beverly Hills and Los Angeles at Beverly Hills Orthopedic Institute are now offering stem cell procedures for hip arthritis. The stem cell therapy typically provides pain relief along with being able to delay or avoid the need for joint replacement. Call (310) 438-5343 for more information and scheduling.

Dr. Raj, Medical Director at Beverly Hills Orthopedic Institute, is a Double Board Certified orthopedic doctor who has been a pioneer in stem cell therapy for musculoskeletal conditions. Several types of stem cell procedures are offered including bone marrow derived along with amniotic derived procedures.

For the bone marrow stem cell procedures, a short outpatient procedure involves harvesting bone marrow from the patient's iliac crest. The stem cells are immediately processed to concentrate the growth factors and cells, and then they are injected into the hip for pain relief and tissue regeneration.

For the amniotic derived procedures, the fluid is obtained from consenting donors after a scheduled c-section procedure. There is no fetal tissue utilized, and the fluid is processed at an FDA regulated laboratory. An immense amount of stem cells, growth factors and hyaluronic acid are present in the amniotic material.

Dr. Raj has performed a significant amount of stem cell procedures utilizing both methods for hip arthritis, with the results being stellar to date. Being Double Board Certified and a sports medicine expert, Dr. Raj also offers stem cell procedures for sports injuries such as tendonitis and ligament injuries. This includes rotator cuff tendonitis, knee injuries, elbow tendonitis and more.

Beverly Hills Orthopedic Institute is the premier stem cell clinic in Los Angeles and Beverly Hills. Dr. Raj is an ABC News Medical Correspondent and a WebMD Medical Expert. For information on how stem cell therapy can help, call Beverly Hills Orthopedic Institute at (310) 438-5343.

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The Rundown Live #276 Open Lines (Prisoner Exchange Psyop,Freemasons,Stem cells) – Video

Posted: June 12, 2014 at 10:49 am


The Rundown Live #276 Open Lines (Prisoner Exchange Psyop,Freemasons,Stem cells)
The Rundown Live #276 Open Lines (Prisoner Exchange Psyop,Freemasons,Stem cells) (6/5/14) On this Thursday edition of The Rundown Live, Kristan and I go over...

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The Rundown Live #276 Open Lines (Prisoner Exchange Psyop,Freemasons,Stem cells) - Video

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A deep dive analysis of erythropoietin market – Video

Posted: June 12, 2014 at 10:48 am


A deep dive analysis of erythropoietin market
Erythropoietin is a glycoprotein hormone produced in the kidney that stimulates the production of red blood cells by bone marrow stem cells. http://www.bigmarketresearch.com/erythropoietin-market.

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Cholesterol Controlled for Good by Gene Therapy in Mice

Posted: June 11, 2014 at 2:54 pm

By altering how a liver gene works, scientists say theyve developed a way to cut cholesterol permanently with a single injection, eliminating the need for daily pills to reduce the risk of heart attack.

In a test in mice, scientists at the Harvard Stem Cell Institute and the University of Pennsylvania disrupted the activity of a gene, called PCSK9, that regulates cholesterol, the fatty material that builds up in veins, hindering blood flow. The process permanently dropped levels of the lipid by 35 to 40 percent, said Kiran Musunuru, the lead researcher.

Thats the same amount of cholesterol youll get with a cholesterol drug, said Musunuru, who is a cardiologist and assistant professor at Harvard. The kicker is we were able to do that with a single injection, permanently changing the genome. Once that changes, its there forever.

Pfizer Inc. (PFE)s Lipitor and AstraZeneca Plc (AZN)s Crestor, both of which target so-called bad cholesterol, are pills that are designed to be taken daily. The prospect of replacing them with the newly tested procedure may be 5 to 10 years away, Musunuru said in a telephone interview.

The PCSK9 gene is the same one now being targeted by Amgen Inc., Sanofi (SAN) and Regeneron Pharmaceuticals Inc. (REGN) with experimental compounds designed to suppress the protein the gene produces. Certain rare PCSK9 mutations are found to cause high cholesterol and heart attacks. Good mutations also exist, and people with them have a heart attack risk that ranges from 47 to 88 percent below average, the researchers said.

Its not too much of a leap to think that if it works as well in mice, it will work as well in humans, said Musunuru, who works in the Cambridge, Massachusetts schools Department of Stem Cell and Regenerative Biology. With one shot, a patient would be like those people born with the good mutations.

The research was published yesterday in Circulation Research, a journal of the American Heart Association.

The approach used a two-part genome-engineering technique that first targets the DNA sequence where the gene sits, and then creates a break in the system. The therapy was carried to the liver using an injected adenovirus.

The genome-editing technique used in the experiment has only been around for about a year and a half, Musunuru said.

The next step is to see how effective the therapy is in human cells, by using mice whose liver cells are replaced with human-derived liver cells, he said. Assessing safety will be the primary concern.

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Cholesterol Controlled for Good by Gene Therapy in Mice

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Katja Schenke-Layland distinguished with TERMIS-EU 2014 Young Scientist Award

Posted: June 10, 2014 at 4:55 pm

10.06.2014 - (idw) Fraunhofer-Institut fr Grenzflchen- und Bioverfahrenstechnik IGB

For her outstanding research in tissue engineering and regenerative medicine Fraunhofer scientist Prof. Dr. Katja Schenke-Layland has been distinguished with the 2014 Young Scientist Award of the Tissue Engineering & Regenerative Medicine International Society European Chapter (TERMIS-EU). The Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and the University Women's Hospital Tbingen biologist Katja Schenke-Layland received the Young Scientist Award of the Tissue Engineering & Regenerative Medicine International Society European Chapter (TERMIS-EU) on 10 June in Genoa, Italy, during the annual conference of the TERMIS-EU. With the prize, the TERMIS-EU acknowledges outstanding achievements of young, promising scientists in the field of tissue engineering and regenerative medicine. Basis for the award were her high quality publications in highly cited journals, leadership activities, grant income from major funding bodies and external recognition amongst the wider international TERM community. Katja Schenke-Layland has published 73 articles, 23 as first and 27 as senior author, with an h-index of 23 and over 1600 total citations.

Scientific career in cardiovascular tissue engineering

Since the beginning of her Ph.D. studies, Katja Schenke-Layland has been developing regenerative strategies to restore the functionality of damaged hearts. She has identified extracellular proteins that are important for heart valve and cardiac muscle development and designed biological approach to incorporate this knowledge into potential therapies. A focus of her current work has been the production of synthetic, biocompatible carrier material to mimic the biological structure of the developing human heart. The scaffolds are designed to attract endothelial progenitor cells circulating in the blood that can repopulate the valve. These cells will begin to modify and rebuild the synthetic scaffolds while in the body, allowing for the potential growth of the scaffolds. The ambitious goal is to further develop this support material to a cell-free off-the-shelf heart valve.

History of a research talent

Katja Schenke-Layland studied biology, sociology and psychology at the University of Jena. She graduated in 2004 with a doctorate in biology, which focused on heart valve tissue engineering and non-invasive tissue analysis. Schenke-Layland was awarded the Family Klee award from the German Society for Biomedical Engineering. She then moved to the United States where she conducted research at the Saban Research Institute of Children's Hospital Los Angeles and the University of California in Los Angeles (UCLA), which was funded by a fellowship from the German Research Foundation (DFG). In 2010, she was promoted to Assistant Research Professor at UCLA and received the award for Morphological Sciences from the American Association of Anatomists for her work in cardiac stem cell research.

Schenke-Layland returned to Germany in 2010 after being awarded the Attract-program grant of the Fraunhofer-Gesellschaft to continue her work in cardiovascular tissue engineering. In 2011, she was appointed Professor for biomaterials in cardiovascular regenerative medicine" at the University Hospital Tbingen, where she leads a research group in parallel with her position at Fraunhofer IGB. Since mid-2013, she co-heads the Department of Cell and Tissue Engineering at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart and has held the appointment of Adjunct Associate Professor at UCLA. Weitere Informationen:http://www.igb.fraunhofer.de/en/press-media/press-releases/2014/katja-schenke-la...

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Katja Schenke-Layland distinguished with TERMIS-EU 2014 Young Scientist Award

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Ravi Jagasia – Modeling ASD using human pluripotent stem cells – Video

Posted: June 10, 2014 at 1:58 am


Ravi Jagasia - Modeling ASD using human pluripotent stem cells
Ravi Jagasia, Human Neural Stem Cell Lab, Roche, IMI EU-AIMS project.

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Cord blood donations a rarity in fertile, charitable Utah

Posted: June 10, 2014 at 1:47 am

(Rick Egan | The Salt Lake Tribune) Doug Schmid in the lab at Utah Cord Bank, Thursday, May 1, 2014. Utah Cord Bank is pushing to expand operations, giving parents more options for banking their babies' cord blood

In 2007, the University of Utah began collecting umbilical cord blood donations for the National Cord Blood Stem Cell bank.

Two years later, it expanded, adding Utahs major labor wards to its public banking effort giving more women in this most fertile of states the opportunity to save a life or contribute to research.

Treating disease with stem cells

Cell therapy

Cell therapies involve transplanting human cells to replace or repair damaged or diseased blood, tissue or organs. Bone marrow transplants of hematopoietic (blood-forming) stem cells are the most common.

How does it work?

Hematopoietic stem cells can form mature blood cells, such as red blood cells (which carry oxygen), platelets (to stop bleeding) and white blood cells (to fight infection). In addition to treating cancer and other blood diseases, they are being tested for use with autoimmune, genetic and a host of other disorders.

Why cord blood?

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BrainStorm launches efficacy study of stem cell therapy for ALS

Posted: June 10, 2014 at 1:47 am

US BrainStorm Cell Therapeutics (OTCBB:BCLI), a developer of adult stem cell technologies for neurodegenerative diseases, said Friday that the first participants had been recruited in a Phase II study of NurOwn in amyotrophic lateral sclerosis (ALS).

The randomised, double-blind, placebo-controlled, multi-centre trial aims to examine the safety and efficacy of transplantation of Autologous Mesenchymal Stem Cells Secreting Neurotrophic Factors (MSC-NTF or NurOwn) in 48 patients with ALS. The study is being carried out at Massachusetts General Hospital (MGH) in Boston, the University of Massachusetts Memorial (UMass) Hospital in Worcester and the Mayo Clinic in Rochester.

NurOwn is BrainStorm's autologous, adult stem cell therapy technology that differentiates bone marrow-derived mesenchymal stem cells (MSC) into MSC-NTF cells, which secrete neurotrophic, or nerve- growth, factors for protection of existing motor neurons, motor neuron growth promotion, and re-establishment of nerve-muscle interaction. BrainStorm holds the rights to develop and commercialise the technology through an exclusive, worldwide licensing deal with Israeli Tel Aviv University's technology transfer company Ramot.

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Scholarship to support student's embryonic stem cell research

Posted: June 9, 2014 at 6:17 am

University of Waikato Biological Sciences student Sarah Appleby has won a C. Alma Baker Postgraduate Scholarship for her agriculture-focused masters research project.

Bovine embryonic stem cell research

The Massey University scholarship, worth $13,000, will go towards Sarahs research into bovine embryonic stem cells.

"Im working with Dr Bjorn Oback at AgResearch on bovine embryonic stem cells and testing their functional potential. Embryonic stem cells have really only been fully isolated from mice and rats, however the group at AgResearch (Ruakura) have developed a method that isolates cells from cows that have very similar properties to the mice embryonic stem cells. Tests have already shown that the cells perform well in the lab, so my work will be focused on seeing if they improve cloning efficiency," says Sarah.

"The aim of this work is to improve our understanding of bovine embryonic stem cells for their use in accelerated animal breeding and biomedical applications. If we can effectively capture the best traits using embryonic stem cells we could develop better biotechnology-based breeding systems to have animals that are more efficient and sustainable to farm."

Hands-on work placements

The former Whangamata Area School student completed a Bachelor of Science (Technology) at Waikato University and is half way through a Master of Science majoring in Biological Sciences, with an emphasis on physiology and genetics.

This is not the first time that Sarah has worked with Dr Oback. During a BSc(Tech) work placement, she spent three months at AgResearch (Ruakura), on a bovine karyotyping project. During another placement, Sarah also spent seven months at AgResearch (Invermay), working under Dr Jenny Juengel on a number of projects related to sheep fertility and reproduction.

"I absolutely loved being part of those teams and getting some hands on lab experience, especially in the IVF field."

Sarah heard about the BSc(Tech) degree while at school. "Nowhere else offered a degree like it, so I chose to come to Waikato. I really liked the idea of the placements, which sounded like the perfect way to get real world experience while completing my degree."

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Scholarship to support student's embryonic stem cell research

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