Posted: May 23, 2014 at 7:41 pm
Personal Project: Stem Cell Research
My Personal Project on stem cell research, including the uses today and in the future. I do not own any videos and they have been cited.
By: marisjeee17
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Personal Project: Stem Cell Research - Video
Posted: May 23, 2014 at 5:53 pm
San Francisco, California (PRWEB) May 22, 2014
The global market for stem cells is expected to reach USD 170.15 billion by 2020, according to a new study by Grand View Research, Inc. Growing prevalence of chronic diseases such as cardiovascular and liver disease, diabetes and cancer coupled with the presence of high unmet medical needs in these disease segments is expected to drive market growth during the forecast period. Moreover, increasing government support pertaining to funding R&D initiatives and the growing demand for medical tourism and stem cell banking services is expected to boost the demand for stem cells over the next six years. The future of this market is expected to be driven by opportunities such as the growing global prevalence of neurodegenerative diseases, increasing demand for contract research outsourcing services and the substitution of animal tissues by stem cells in the
The stem cells technology market was valued at USD 12.88 billion in 2013 and is expected to grow at a CAGR of over 12.0% during the forecast period. This market was dominated by the cell acquisitions technology segment in terms of share in 2013 owing to the fact that this technology serves as the foremost step to process involving stem cells culture. The global stem cell acquisition technology market is expected to reach USD 10.88 billion by 2020, growing at a CAGR of over 14.0% over the next six years.
The report Stem Cells Market Analysis By Product (Adult Stem Cells, Human Embryonic Cells, Pluripotent Stem Cells), By Application (Regenerative Medicine, Drug Discovery and Development) And Segment Forecasts To 2020, is available now to Grand View Research customers at http://www.grandviewresearch.com/industry-analysis/stem-cells-market
Request Free Sample of this Report @ http://www.grandviewresearch.com/industry-analysis/stem-cells-market/request
Further key findings from the study suggest:
Browse All Biotechnology Market Reports @ http://www.grandviewresearch.com/industry/biotechnology
For the purpose of this study, Grand View Research has segmented the global stem cells market on the basis of product, application, technology and region:
Latest Reports Published By Grand View Research:
Global Polymethyl Methacrylate (PMMA) Market Expected to Reach USD 10.87 Billion by 2020 (https://www.grandviewresearch.com/industry-analysis/polymethyl-methacrylate-pmma-industry)
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Stem Cells Market By Application (Regenerative Medicine), By Technology (Acquisition, Sub-Culture), By Product (Adult ...
Posted: May 23, 2014 at 5:52 pm
PUBLIC RELEASE DATE:
22-May-2014
Contact: Luise Dirscherl presse@lmu.de 49-892-180-3243 Ludwig-Maximilians-Universitt Mnchen
Slight modifications in their genome sequences play a crucial role in the conversion of pluripotent stem cells into various differentiated cell types. A team at Ludwig-Maximilians-Universitaet (LMU) in Munich has now identified the factor responsible for one class of modification.
Every cell contains stored hereditary information, encoded in the sequence of nucleobases that make up its DNA. However, in any given cell type, only a fraction of this information is actually used. Which genes are activated and which are turned off is in part determined by a second tier of information which is superimposed on the nucleotide sequences that provide the blueprints for protein synthesis. This so-called epigenetic level of control is based on the localized, and in principle reversible, attachment of simple chemical tags to specific nucleotides in the genome. This system plays a major role in the regulation of gene activity, and enables the selective expression of different functions in differentiated cell types.
This explains why such DNA modifications play a major role in the differentiation of stem cells. "Several unusual nucleobases have been found in the genomes of stem cells, which are produced by targeted chemical modification of the known building blocks of DNA. These 'atypical' bases are thought to be important in determining what types of differentiated cells can be derived from a given stem cell line," says Professor Thomas Carell from the Department of Chemistry at LMU. All of the unconventional bases so far discovered are derived from the same standard base cytosine. Furthermore, Carell and his team have shown in earlier work that so-called Tet enzymes are always involved in their synthesis.
Base oxidation regulates gene activity
In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other than cytosine is also modified in embryonic stem cells of mice. Moreover, Tet is at work here too. "During the development of specialized tissues from stem cells, enzymes belonging to the Tet family also oxidize the thymidine base, as we have now shown with the aid of highly sensitive analytical methods based on mass spectrometry. The product of the reaction, hydroxymethyluracil, was previously and as it now turns out, erroneously thought to be synthesized by a different pathway," Carell explains.
The precise function of hydroxymethyluracil remains unclear. However, using an innovative method for the identification of factors capable of binding to and "reading" the chemical tags that characterize unconventional DNA bases, Carell and colleagues have shown that stem cells contain specific proteins that recognize hydroxymethyluracil, and could therefore contribute to the regulation of gene activity in these cells. "We hope that these new insights will make it possible to modulate the differentiation of stem cells causing them to generate cells of a particular type," says Carell. "It would be wonderful if we were one day able to generate whole organs starting from differentiated cells produced, on demand, by stem cell populations."
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Stem-cell research: A new genetic switching element
Posted: May 23, 2014 at 5:45 pm
May 22, 2014
The world has great expectations that stem cell research one day will revolutionize medicine. But in order to exploit the potential of stem cells, we need to understand how their development is regulated. Now researchers from University of Southern Denmark offer new insight.
Stem cells are cells that are able to develop into different specialized cell types with specific functions in the body. In adult humans these cells play an important role in tissue regeneration. The potential to act as repair cells can be exploited for disease control of e.g. Parkinson's or diabetes, which are diseases caused by the death of specialized cells. By manipulating the stem cells, they can be directed to develop into various specialized cell types. This however, requires knowledge of the processes that regulate their development.
Now Danish researchers from University of Southern Denmark report a new discovery that provides valuable insight into basic mechanisms of stem cell differentiation. The discovery could lead to new ways of making stem cells develop into exactly the type of cells that a physician may need for treating a disease.
"We have discovered that proteins called transcription factors work together in a new and complex way to reprogram the DNA strand when a stem cell develops into a specific cell type. Until now we thought that only a few transcription factors were responsible for this reprogramming, but that is not the case", explain postdoc Rasmus Siersbaek, Professor Susanne Mandrup and ph.d. Atefeh Rabiee from Department of Biochemistry and Molecular Biology at the University of Southern Denmark.
"An incredibly complex and previously unknown interplay between transcription factors takes place at specific locations in the cell's DNA, which we call 'hotspots'. This interplay at 'hotspots' appears to be of great importance for the development of stem cells. In the future it will therefore be very important to explore these 'hotspots' and the interplay between transcription factors in these regions in order to better understand the mechanisms that control the development of stem cells", explains Rasmus Siersbaek.
"When we understand these mechanisms, we have much better tools to make a stem cell develop in the direction we wish", he says.
Siersbaek, Mandrup and their colleagues made the discovery while studying how stem cells develop into fat cells. The Mandrup research group is interested in this differentiation process, because fundamental understanding of this will allow researchers to manipulate fat cell formation.
"We know that there are two types of fat cells; brown and white. The white fat cells store fat, while brown fat cells actually increase combustion of fat. Brown fat cells are found in especially infants, but adults also have varying amounts of these cells.
"If we manage to find ways to make stem cells develop into brown rather than white fat cells, it may be possible to reduce the development of obesity. Our findings open new possibilities to do this by focusing on the specific sites on the DNA where proteins work together", the researchers explain.
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New insight into stem cell development
Posted: May 23, 2014 at 5:44 pm
Whiplash headaches 11 months after stem cell therapy by Dr Harry Adelson
Neil discusses his outcome 11 months after his stem cell therapy by Dr Harry Adelson for the treatment of his post-whiplash headache syndrome http://www.docereclinics.com.
By: Harry Adelson, N.D.
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Whiplash headaches 11 months after stem cell therapy by Dr Harry Adelson - Video
Posted: May 23, 2014 at 5:44 pm
Poway, California (PRWEB) May 22, 2014
Zeke was in pain from arthritis caused by an old injury and was facing possible surgery on both knees. Christine Ponsness-Wetzel, DVM, at Pend Oreille Veterinary Service determined that Zeke was a good candidate for stem cell therapy by Vet-Stem, Inc. as an alternative, and just a few months later, he now has a bounce back in his step.
Zeke is a 125-pound Leonberger who lives in Idaho and enjoys going on back country ski trips. Zekes hobbies came to a halt two years ago when he was diagnosed with a partial cruciate ligament tear. He had gone lame and two weeks of rest was recommended, but his owners did not see improvement. After a month of rest, x-rays revealed arthritis had developed in one of Zekes knees.
After a year of pain medications to control the discomfort and pain, Zeke started having more difficulties. He had a delayed ability to comfortably bend his leg, often needed help getting up from a laying position, and would whimper in pain. This time, x-rays would reveal arthritis in both knees. After a few months of increased pain medications and only mild improvement, Zekes owners opted for stem cell therapy with Dr. Ponsness-Wetzel.
Zeke was still quite active and happy, so the thought of double knee surgery and the long recovery time was not in my books, so we opted for stem cell therapy, Zekes owner explains. It has been four months since the stem cell injections (both knees and an IV dose) and Zeke has definitely improved. He no longer needs help getting up. He does not whimper in pain. His delay in bending his knee is non-existent, and his pain medication has been reduced by about 80%. Hikes are no longer sheer drudgery and he has a bounce in his step that I forgot existed.
Pend Oreille Veterinary Services celebrates its 50th anniversary in the Bonner County, providing basic health care services to small animals and reptiles, as well as cutting edge therapies such as acupuncture, laser, and stem cells. Pend Oreille Veterinary Services also offers boarding and grooming to the cities around their two locations in Ponderay and Bonners Ferry. To find out more about Pend Oreille Veterinary Service and Vet-Stem Cell Therapy with Dr. Ponsness-Wetzel, visit http://www.sandpointvets.com.
About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine visit http://www.vet-stem.com or call 858-748-2004.
Posted: May 22, 2014 at 6:46 pm
Wrapping up the stem cells for transportation
At Anthony Nolan, we rely on a team of volunteer couriers to transport lifesaving stem cells around the world. They have just 72 hours to get the cells to their destination. The bag of lifesaving...
By: Anthony Nolan
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Wrapping up the stem cells for transportation - Video
Posted: May 22, 2014 at 6:46 pm
The journey of a stem cell courier
At Anthony Nolan, we arrange lifesaving stem cell transplants for people with blood cancer. And we rely on a team of volunteers to transport those stem cells around the world. Peter Hodes...
By: Anthony Nolan
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The journey of a stem cell courier - Video
Posted: May 22, 2014 at 6:46 pm
The Hope of Stem Cell Research at Riley HospitalScott Goebel, M D Riley Hospital for Children at IU
By: Martin Center
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The Hope of Stem Cell Research at Riley HospitalScott Goebel, M D Riley Hospital for Children at IU - Video
Posted: May 22, 2014 at 8:00 am
If the notion of biting into a hamburger made from lab-cultured stem cells doesn't make your mouth water, perhaps your brain can find it appetizing.
That's the view of two Dutch professors who argue that meat grown in enormous test tubes, or bioreactors, can provide an ever more prosperous world with a plentiful, environmentally friendly and humane source of protein.
Cultured meat, they say, is the food of the future.
"Rising global demand for meat will result in increased environmental pollution, energy consumption and animal suffering," the Wageningen University professors wrote Tuesday in the journal Trends in Biotechnology.
"As large parts of the world become more prosperous, the global consumption of meat is expected to rise enormously in the coming decades," they wrote.
This growing demand for meat necessitates a "protein transition," according to bioethicist Cor van der Weele and bioprocessing engineer Johannes Tramper. This transition will probably involve substituting some vegetable products for meat, keeping fewer animals on factory farms and possibly eating insects.
The authors envision a day when "every village" maintains a cultured meat facility in which muscle stem cells from pigs, cows, chicken, fish or any other animal are allowed to grow and reproduce in 5,200-gallon processing tanks.
The reproducing cells are suspended in a growth medium that provides them with nutrition, while mechanical paddles agitate the solution.
When the cell population reaches the desired density -- perhaps in a month, the authors say -- an enzyme and binding protein are added to the solution. At that point, the agitation stops and the tissue cells form small clumps and settle to the bottom of the tank.
Finally, the authors say, the tank is drained of the growing medium and the remaining "meat slurry" is pressed into a mincemeat-type cake and sold.
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Hungry for a helping of test tube meat? Maybe you should be
