Posted: May 8, 2014 at 4:45 pm
Stem Sport - Faster Recovery With Nutrition For Your Stem Cells
http://www.YourOwnStemCells.Info..........................Find out how a natural supplement will help you recover faster after exercise or an injury. Increase strength,...
By: Linn Fuller
Excerpt from:
Stem Sport - Faster Recovery With Nutrition For Your Stem Cells - Video
Posted: May 8, 2014 at 4:45 pm
Body Renewal with Luminesce Adult Stem Cells
FranchiseStemcell Body Renewal with Luminesce Adult Stem Cells from Jeunesse Global.
By: Franchise StemCell
View original post here:
Body Renewal with Luminesce Adult Stem Cells - Video
Posted: May 8, 2014 at 4:45 pm
Embryonic Stem Cell Research vs. Adult Stem Cell research f
Final Project by Thomas Kraft on embryonic and adult stem cell research.
By: Thomas Kraft
Read the original here:
Embryonic Stem Cell Research vs. Adult Stem Cell research f - Video
Posted: May 7, 2014 at 4:50 pm
Stem cell research pros
by Ashley, Braxton Maddy.
By: Ashley Parfait
Excerpt from:
Stem cell research pros - Video
Posted: May 7, 2014 at 12:02 pm
22 hours ago Cells with activated Wnt can no longer be reprogrammed (in green) are located on the periphery; cells that can be reprogrammed are aggregated anad can be seen in the center of the image (in red) Credit: CRG
In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar way to embryonic stem cells, and hence have enormous potential for regenerative medicine.
However, although there are many research groups around the world studying this process, it is still not completely understood, it is not totally efficient, and it is not safe enough to be used as the basis for a new cell therapy.
Now, researchers at the Centre for Genomic Regulation (CRG) in Barcelona have taken a very important step towards understanding cell reprogramming and its efficiency: they have discovered the key role of the Wnt signalling pathway in transforming adult cells into iPS cells.
"Generally, transcription factors are used to try to increase or decrease the cell reprogramming process. We have discovered that we can increase the efficiency of the process by inhibiting the Wnt route", explains Francesco Aulicino, a PhD student in the Reprogramming and Regeneration group, led by Maria Pia Cosma and co-author of the study that has just been published in Stem Cell Reports.
The Wnt signaling pathway is a series of biochemical reactions that are produced in cells. In frogs or lizards, for example, these reactions are those that allow their extremities to regenerate if the animal suffers an injury. Although in general, humans and mammals have lost this regenerative capacity, the Wnt pathway is involved in numerous processes during embryonic development and cell fusion.
As it is in reprogramming. The researchers have studied how the Wnt route behaves throughout the entire process of transforming cells into iPS cells, which usually lasts two weeks. It is a very dynamic process that produces oscillations from the pathway, which is not active all the time. "We have seen that there are two phases and that in each one of them, Wnt fulfils a different function. And we have shown that by inhibiting it at the beginning of the process and activating it at the end we can increase the efficiency of reprogramming and obtain a larger number of pluripotent cells", indicates Ilda Theka, also a PhD student in Pia Cosma's group and a co-author of the article.
To artificially control the pathway, the group has employed a chemical molecule, Iwp2, which is a Wnt secretion inhibitor that does not permanently alter the cells, something which other research into reprogramming using different factors has still has not been able to acheive.
They have also seen that the exact moment when the Wnt pathway is activated is crucial. Doing it too early, makes the the cells begin to differentiate, for example into neurones or endodermal cells, and they are not reprogrammed.
"It is a very important and an innovative advance in the field of cell reprogramming, because until now this was a very inefficient process. There are many groups trying to understand the mechanism by which adult cells become pluripotent, and what blocks that process and makes only a small percentage of cells end up being reprogrammed. We are providing information on why it happens", says Theka.
The rest is here:
One step closer to cell reprogramming
Posted: May 7, 2014 at 12:02 pm
Stem Sport - Faster Recovery with Your Own Stem Cells
http://www.YourOwnStemCells.Info.
By: Linn Fuller
Continue reading here:
Stem Sport - Faster Recovery with Your Own Stem Cells - Video
Posted: May 7, 2014 at 12:02 pm
Contact Information
Available for logged-in reporters only
Newswise LA JOLLABy carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cellsthose that can form breast tissuealive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.
What weve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor, says Peter C. Gray, a staff scientist in Salks Clayton Foundation Laboratories for Peptide Biology, who collaborated on the new work with Benjamin T. Spike, a senior research associate in the laboratory of Salk Professor Geoffrey M. Wahl.
The results of the study were published in the April 8th issue of the journal Stem Cell Reports.
Mammary stem cells can give rise to new breast cells during fetal development, adolescence or lactation and may also play a role in breast cancer, so they represent a highly promising avenue for breast cancer research. But isolating the stem cells and maintaining them in the lab to study has been difficult.
There was a lot of prior work demonstrating that mammary-specific stem cells exist, but it was virtually impossible to isolate them in numbers from an adult, says Spike. But we previously found we could turn to early development, when the stem cells are present in higher proportions.
When the researchers used fetal breast tissue rather than adult tissue from mice, they were able to pinpoint which cells were stem cells but the cells would rapidly change when grown in a dish. A defining property of all stem cells is that when they divide into two new cells, they can form both stem cells and differentiated cells (cells on their way to becoming a specific type of tissue).
Spike and Gray grew the mammary stem cells in culture dishes and stained them so that new stem cells appeared a different color from differentiated mammary cells. Then, they began testing the effects of two proteinsknown as CRIPTO and GRP78that play significant roles in both stem cell biology and embryonic development.
In normal conditions, we first see the cells as yellowthe combination of red and green within a single cellthen later see cells that are either red or green, showing that our cells had the capacity to make two different types of mature cells, says Spike. But then when we do the experiment again and start changing protein levels, the ratio of these cells becomes very different.
Read more from the original source:
Ability to Isolate and Grow Breast Tissue Stem Cells Could Speed Cancer Research
Posted: May 7, 2014 at 12:02 pm
PUBLIC RELEASE DATE:
5-May-2014
Contact: Katrina Norfleet knorfleet@arvo.org 240-221-2924 Association for Research in Vision and Ophthalmology
Orlando, Fla. In two separate studies, scientists have developed methods to convert non-embryonic stem cells into eye cells that could be used to restore sight. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando.
In the first method, researchers converted cells taken from the front of a patient's eye into stem cells, which were then programmed to become nerve cells found in the back of the eye. The second study involved introducing stem cells to a single growth factor, which caused them to develop into tissue resembling the developing eye.
Both outcomes will play important roles toward generating sources of transplantable cells to replace damaged tissue in patients with impaired vision.
Abstract Title: Derivation, Characterization and Retinal Neural Induction of Human Tenon's -Derived iPS Cells
Presentation Start/End Time: Monday, May 5, 8:30 10:15am Location: Exhibit/Poster Hall SA Session Number: 218
Abstract Title: The formation of primitive ocular structures and stratified neural retina from human pluripotent stem cells
Presentation Start/End Time: Monday, May 5, 8:30 10:15am Location: Exhibit/Poster Hall SA Session Number: 218
See the original post:
Scientists convert stem cells to eye tissue
Posted: May 7, 2014 at 12:01 pm
PUBLIC RELEASE DATE:
5-May-2014
Contact: Katrina Norfleet knorfleet@arvo.org 240-221-2924 Association for Research in Vision and Ophthalmology
Orlando, Fla. Scientists have developed a model that mimics the complex structure of the cornea to enable the transplant of healthy corneal stem cells. The research is being presented at the 2014 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Orlando Fla.
Used to restore sight, corneal stem cells live in a specific physical environment. Transplanting these stem cells requires accurate mimicry of their natural surroundings during transport. In this work, vision scientists have recreated the 3D architecture where corneal stem cells naturally reside.
The cornea is the transparent window at the front of the eye. When the outermost cell layer of the cornea is damaged, vision is severely impaired. Treatment can include a transplant of healthy corneal stem cells to replace the lost cells.
Abstract Title: Tissue engineering the human limbal crypts: further characterization of an in vitro model
Presentation Start/End Time: Monday, May 5, 3:45 4pm Location: S 331A-D Session Number: 271
###
The Association for Research in Vision and Ophthalmology (ARVO) is the largest eye and vision research organization in the world. Members include some 11,500 eye and vision researchers from over 70 countries. ARVO encourages and assists research, training, publication and knowledge-sharing in vision and ophthalmology.
See more here:
Simulated model of eye's 3D structure facilitates stem cells transplant
Posted: May 7, 2014 at 11:55 am
Charges of syndicated estafa, illegal medical practice and murder were filed on Tuesday against Dr. Zoharina Antonia Pedrera Carandang, also known as Dr. Antonia Carandang-Park, for practicing stem cell therapy on 23-year-old cancer patient Katherine Kate Tan. The treatment was alleged to have caused the Tan's death.
The charges were filed by Kate's father Bernard Tan before the Tagaytay Municipal Fiscal's Office. Aside from Carandang, owner and operator of Tagaytay-based Green & Young Health and Wellness Center, also charged were Joy Dimaranan, Estrella Maranan, Bebot Maranan and several other employees of the wellness center.
Tan also filed on Tuesday a separate administrative complaint against Park before Tagaytay's Office of the City Administrator, GMA News TV's Quick Response Team (QRT) reported.
According to the City Administrator's Office, Park had, in the past, applied for a permit to operate a medical clinic but was denied for failing to present the necessary documents, such as a Department of Health (DOH) certification.
Park, was, however, granted a permit to operate a massage clinic in 2012.
A caretaker at the wellness center, who received the copy of the criminal and administrative complaints, said Park had left the clinic Tuesday morning.
The Fiscal's Office also sent a letter to Park requiring her to respond to the complaint within two days, otherwise an investigation based only on the evidence presented by the Tans would be pursued.
The Office of the City Administrator also prohibited the wellness clinic from operating until a reply to the administrative complaint was filed.
Alternative treatment
In a separate complaint filed last month before the National Bureau of Investigation (NBI), Tan alleged that Park was not licensed by the Professional Regulation Commission (PRC) to practice medicine in the Philippines.
See the original post:
Unlicensed stem cell doctor slapped with charges over patient's death
